LOCUS       DAIGUC010000001        97863 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.001, whole genome shotgun sequence.
ACCESSION   DAIGUC010000001 DAIGUC010000000
VERSION     DAIGUC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 97863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.001"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(176..2347)
                     /gene="copB"
                     /locus_tag="NOB46_000001"
     CDS             complement(176..2347)
                     /gene="copB"
                     /locus_tag="NOB46_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HCI1056992.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2367..4553)
                     /locus_tag="NOB46_000002"
     CDS             complement(2367..4553)
                     /locus_tag="NOB46_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCI1056993.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="NOB46_000003"
     CDS             complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="NOB46_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HCI1056994.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4775..5215)
                     /locus_tag="NOB46_000004"
     CDS             complement(4775..5215)
                     /locus_tag="NOB46_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HCI1056995.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5289..5828)
                     /locus_tag="NOB46_000005"
     CDS             complement(5289..5828)
                     /locus_tag="NOB46_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HCI1056996.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6443..7909)
                     /locus_tag="NOB46_000006"
     CDS             complement(6443..7909)
                     /locus_tag="NOB46_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1056997.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="NOB46_000007"
     CDS             complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="NOB46_000007"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI1056998.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10825..11184)
                     /locus_tag="NOB46_000008"
     CDS             complement(10825..11184)
                     /locus_tag="NOB46_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCI1056999.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11214..11555)
                     /locus_tag="NOB46_000009"
     CDS             complement(11214..11555)
                     /locus_tag="NOB46_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057000.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11552..12226)
                     /locus_tag="NOB46_000010"
     CDS             complement(11552..12226)
                     /locus_tag="NOB46_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI1057001.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13279..14577)
                     /gene="asnS"
                     /locus_tag="NOB46_000011"
     CDS             complement(13279..14577)
                     /gene="asnS"
                     /locus_tag="NOB46_000011"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCI1057002.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14617..15807)
                     /locus_tag="NOB46_000012"
     CDS             complement(14617..15807)
                     /locus_tag="NOB46_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1057003.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15828..16355)
                     /locus_tag="NOB46_000013"
     CDS             complement(15828..16355)
                     /locus_tag="NOB46_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HCI1057004.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16402..19191)
                     /locus_tag="NOB46_000014"
     CDS             complement(16402..19191)
                     /locus_tag="NOB46_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI1057005.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(19338..19538)
                     /locus_tag="NOB46_000015"
     CDS             complement(19338..19538)
                     /locus_tag="NOB46_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1057006.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(19991..20311)
                     /locus_tag="NOB46_000016"
     CDS             complement(19991..20311)
                     /locus_tag="NOB46_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057007.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(20814..21932)
                     /locus_tag="NOB46_000017"
     CDS             complement(20814..21932)
                     /locus_tag="NOB46_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057008.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            22403..23710
                     /locus_tag="NOB46_000018"
     CDS             22403..23710
                     /locus_tag="NOB46_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCI1057009.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            23831..25030
                     /locus_tag="NOB46_000019"
     CDS             23831..25030
                     /locus_tag="NOB46_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI1057010.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(25057..26325)
                     /locus_tag="NOB46_000020"
     CDS             complement(25057..26325)
                     /locus_tag="NOB46_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HCI1057011.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLFYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPILQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(26489..27136)
                     /locus_tag="NOB46_000021"
     CDS             complement(26489..27136)
                     /locus_tag="NOB46_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HCI1057012.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(27545..28048)
                     /locus_tag="NOB46_000022"
     CDS             complement(27545..28048)
                     /locus_tag="NOB46_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1057013.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(28171..28935)
                     /locus_tag="NOB46_000023"
     CDS             complement(28171..28935)
                     /locus_tag="NOB46_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCI1057014.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            29043..29318
                     /locus_tag="NOB46_000024"
     CDS             29043..29318
                     /locus_tag="NOB46_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCI1057015.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            29983..30933
                     /gene="yidC"
                     /locus_tag="NOB46_000025"
     CDS             29983..30933
                     /gene="yidC"
                     /locus_tag="NOB46_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI1057016.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            31037..32353
                     /locus_tag="NOB46_000026"
                     /pseudo
     CDS             31037..32353
                     /locus_tag="NOB46_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(33054..33254)
                     /locus_tag="NOB46_000027"
     CDS             complement(33054..33254)
                     /locus_tag="NOB46_000027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057017.1"
                     /translation="MAEMHDHLLHSICERTGLSEEEVNQKLMEISEAMNKGVDFSMNQ
                     LDDFLAQHMKDALASDAADSVE"
     gene            complement(33604..33951)
                     /locus_tag="NOB46_000028"
     CDS             complement(33604..33951)
                     /locus_tag="NOB46_000028"
                     /inference="COORDINATES: protein motif:HMM:NF019886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI1057018.1"
                     /translation="MDHLHDHDAENRLESNYARYLGGIEQTIEDSYTQDCMMSYTPDI
                     VEKIAPTDFKKMERKRLQEEIQKLTFNQRKVIEHYYFLNKNQQQIARDLRMSHAEITK
                     TLKRAFAVMKEVY"
     gene            complement(34346..34723)
                     /locus_tag="NOB46_000029"
     CDS             complement(34346..34723)
                     /locus_tag="NOB46_000029"
                     /inference="COORDINATES: protein motif:HMM:NF025104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057019.1"
                     /translation="MFFLAFLYLYIANVKYFSKWPLLLFWIISCVLLLVKNAVFQFLL
                     KKIGSKSHTRVLVVENGNLAKEYGLAMLSDPDADANIIGYVKDRKKEDILLEEPGFAN
                     YGDGLAKLKYFGRISDVQDVIVK"
     gene            complement(34747..35070)
                     /locus_tag="NOB46_000030"
     CDS             complement(34747..35070)
                     /locus_tag="NOB46_000030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057020.1"
                     /translation="MIDRRDDSDRCWSIRYYYKGRINEIIKERFWNTVFDCIGDAASI
                     FVAYLLAMFICYHVLEAAPGINMLSVPYLMMAALYSILIADFLRIFRATNKTYFRKYQ
                     NGFLK"
     gene            complement(35132..35608)
                     /locus_tag="NOB46_000031"
     CDS             complement(35132..35608)
                     /locus_tag="NOB46_000031"
                     /inference="COORDINATES: protein motif:HMM:TIGR01670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057021.1"
                     /translation="MSQIKFLVMDVDGTLTDGKIYMGECGEIMKAFNIKDGCAIHDIV
                     RAHNIEPIIITGRRSKILENRCKELGINILYQGIDNKIEKLLEITSDLSTVAYIGDDI
                     NDLSCMHPVKSAGGIVACPHDAVKKVLEISDFIAEHDGGNGAVREFVEWLVDTQNN"
     gene            complement(35625..35990)
                     /locus_tag="NOB46_000032"
     CDS             complement(35625..35990)
                     /locus_tag="NOB46_000032"
                     /inference="COORDINATES: protein motif:HMM:TIGR00022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCI1057022.1"
                     /translation="MELEEGRYDLSNGIYLNVESYDIYRFEERMYESHLKYLDIQCIL
                     LGCEYIVVESISNLQIEVDYSADKDIVFYSNSIVGNCVLLEGGKLLLLTPEDAHMPCI
                     RVNESAKVKKAVFKISINY"
     gene            complement(36073..37038)
                     /locus_tag="NOB46_000033"
     CDS             complement(36073..37038)
                     /locus_tag="NOB46_000033"
                     /inference="COORDINATES: protein motif:HMM:TIGR00393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HCI1057023.1"
                     /translation="MDKIIEAKRVFDIEIEALKRTRDCLGKTFVRILDAIVNCEGKVI
                     ITGMGKPGHIAAKLAATFASLGTPAFRLHPAEAMHGDLGMVSEKDIVIAISYSGESDE
                     IVKILPNIKMIGATLIGITGNSKSTLATASDIVQILPEFEEACYLGLAPTSSATSVLC
                     YGDALAVVASGIYGFKDSDFGKFHPAGSLGKKLILKVSDLMSHGNEIPMVNSGTLLMD
                     AISVMSNKGLGIVSVIDQDGTLKGIITDGDLRRIIERKVDIYSVEIDDVMIANPKVFT
                     KDKLAVDALRFLKANSINILPIIDDEGMLVGTITWQQIVKAGIVA"
     gene            complement(37147..37923)
                     /gene="kdsA"
                     /locus_tag="NOB46_000034"
     CDS             complement(37147..37923)
                     /gene="kdsA"
                     /locus_tag="NOB46_000034"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010388312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HCI1057024.1"
                     /translation="MNRLMLIAGPCVIESEENVMLIAKTIKEITEKLDIDYYFKASFD
                     KANRTSITSYRGPGIEEGLKILKKVKETYGLKICTDIHEPWQAEKAAEVCDILQIPAF
                     LCRQTDLLVAAAKTGKIINVKKAQFLAPWDMKNVINKLVEAGNSNIMLCERGTSFGYN
                     TLVVDMTSIVEMKKFGYPVVMDATHSVQKPGGKGDVTGGNRNNVEPLAKAAVATGADA
                     LFFEVHPDPDNALSDGPNMVLLDEFEGLLERVLKVYNAVR"
     gene            complement(37925..38662)
                     /gene="kdsB"
                     /locus_tag="NOB46_000035"
     CDS             complement(37925..38662)
                     /gene="kdsB"
                     /locus_tag="NOB46_000035"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: protein motif:HMM:NF003952.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HCI1057025.1"
                     /translation="MKTIAIIPSRYGSSRFPGKPLAMISSKPMIQWVYENVSKAAMLD
                     AVYVATDDKRIFDCVESFGGMALMTSDKHTCGTDRLAECAEILQLRDEDLVLNIQGDE
                     PLIKAEMIADLYSCFDNDEVYMGTLKKHIEVQEELDNPNVVKVINDVNDYAIYFSRFC
                     VPYERDGKNSLHFKHIGVYGYKTWFLKKYSTMPKTPLEVSESLEQLRVLESGFKIRVK
                     ETKYQTVGVDTPEQIQQVEDELRKEGL"
     gene            complement(38659..40086)
                     /locus_tag="NOB46_000036"
     CDS             complement(38659..40086)
                     /locus_tag="NOB46_000036"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024832.1,HMM:NF026018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HCI1057026.1"
                     /translation="MNRLIKNYAYNLCYQILVMILPIITTPYVSRVLKAEGVGEFNYS
                     YAIVSVAVIIAQLGTNMYGQREIAYVQNDKIRRSGVFWSIFVIRIISSFIVFPVYILI
                     SATLHSYTVLLISMSVYLVANLFDVSWFFQGMEDFKKTAIRSMVVKLIGLVLIFLLVK
                     NENDVVLYSVILAGTELLGNALLCCHIPKYVRRISIHDISITPHIRPILGLFLPTAAV
                     YIYTYVNKIILGIFSTDVQVGLYSQPEKIVKLLMTVITSLGAVMLPHIAVAVKENNID
                     RIRKEVLNAVSFVFCIGAPMVVGAIIIANTFIPWFLGDGYAKSVSLFQLLSPLILIIG
                     FASVVGQAVLIPMKRQRVYTFSIMTGAVINLVVNLALIPHLEAIGAAIGTIFAELTVT
                     AIQFYEVRNCIELKMASIITNVKNYLIGALIMGGVGGYVSSKLPNSVISTFITVILCI
                     LLYSILLICMKDKLLMDYLKRRKNR"
     gene            complement(40088..41401)
                     /locus_tag="NOB46_000037"
     CDS             complement(40088..41401)
                     /locus_tag="NOB46_000037"
                     /inference="COORDINATES: protein motif:HMM:TIGR04370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HCI1057027.1"
                     /translation="MIYQLLIVEFILILIMYILSNRCFISPAFIAIALFFLATCCVVY
                     NIEFWNVQYSKKTLWFITTGFLAMCIPEMYILFLDYLSKKRVDNYHQNQYKIEYVQIY
                     PSRQLNLIFALLSVVFFGVLLVEILRKGDYSTLGLYAIGAAKSDETQNSVIARFGISL
                     ITGLNLAYLYVFINNVIRCKERVLSNIKYLFPTLMYILCMFISGNRVFLVKLFAIVFL
                     IYIVMKSDVSPRGRVPVMQVVRKTLFVAVAILAVFYALRGITKVNSTAATREFSDYIT
                     YYIGSPVYMLDKYLQRYSPELNWGAKSLTSLVEMFGIEPEFKNAYIHVGGDSNFAGNE
                     FSWFQRPYSDFGWLGMLVFTFIVFWIFSWNIHIRINKEKNRRRRKYYILITAYFFYIP
                     VMSFYYCQMCFAFSITNIFSVVVACLLVREFTKRQDEIIFKIKEE"
     gene            complement(41402..42547)
                     /locus_tag="NOB46_000038"
     CDS             complement(41402..42547)
                     /locus_tag="NOB46_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HCI1057028.1"
                     /translation="MKKARVLAFYLPQFHPVRENDIMWGKGFTEWTNVAKAKPLFKNH
                     YQPQIPADLGFYDLRISEVRKQQAEMAKKYGVEGFCYWHYWFGNGKRILELPFNEVLQ
                     SGEPDFPFCLGWANHSWSNKTWQKSKHFTKDVVFLEQTYPGDEDYILHFKSILPALKD
                     DRYIKVDGKPLFLVFAPDSIPDSAHFISLWNKLAKENGFEGIYFVARVTSVDNKFDLS
                     SMTDVAVHNRFQRFLDMGYDAINSDMQRYAELKISGYWKRGIKSIMRKTVGNFSANLY
                     PYDKIMENFYCEEEKRECVHPQLIPRLDRTPRSGKDARVYVDSTPEKFGNAIDRALSY
                     VQDKEPEHRILFLQAWNEWGEGNYMEPDLVFGCEYLEILRKKILGEE"
     gene            complement(42544..43350)
                     /locus_tag="NOB46_000039"
     CDS             complement(42544..43350)
                     /locus_tag="NOB46_000039"
                     /inference="COORDINATES: protein motif:HMM:NF014075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF115 domain-containing protein"
                     /protein_id="HCI1057029.1"
                     /translation="MVNIKIRKVIHRIPPILKLMRFVVDVQNKYFYDKFCKNTDNIQR
                     IEKLRNKFLGETCFIVGNGPSLTMEDLELIKDKDCFAANLIFKIFDKTQWRPKYYFIQ
                     DRYADTGNELDDIDLEYMFIGDYYWRVRGMHNPNAICIHSEQSVGGKNIKFSEDISKS
                     IVSHETVTYSMIQAAVYMGYKKIYLLGMDHSYALTYNADGTVSEDKTIRSHFFEDKNA
                     NEVIASIVGMNQAYIRAREFCESNNIKIYNATRGGKLNWFDRITLEEAVK"
     gene            complement(43409..43597)
                     /locus_tag="NOB46_000040"
     CDS             complement(43409..43597)
                     /locus_tag="NOB46_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016396235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HCI1057030.1"
                     /translation="MVVKGTSDDFYHANDEGGLAWNDPEIGIEWPQVLGEYKGNASAE
                     GYIFEDDTPLNISEKGQR"
     gene            complement(43945..44079)
                     /locus_tag="NOB46_000041"
     CDS             complement(43945..44079)
                     /locus_tag="NOB46_000041"
                     /inference="COORDINATES: protein motif:HMM:NF013621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HCI1057031.1"
                     /translation="MKEKVIEYTTGVYDMFHIGHLNVMRNAKAQCDFLIVGVSTDEPV
                     "
     gene            complement(44420..45553)
                     /locus_tag="NOB46_000042"
     CDS             complement(44420..45553)
                     /locus_tag="NOB46_000042"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI1057032.1"
                     /translation="MRQKIRVLHIAQAAGGVDCYIRMLLKYLDKEKFENILICSQDFC
                     ETDYANLVLSFKQIKLTREIDLNDLKAIVIIRKLIKKYNPDIVYAHSSKAGAITRVAK
                     IGLKNYCVYNPHGWAFNMRCSVKKKMLYTAIEKIAALFCDKIICISDAEKQSALKKRI
                     CCEDKLQVIFNGVDIEAYRNKAHGEVKRESLNIPQDAFVVGMVGRISPQKAPEIFIKM
                     ARLVKNKIPEAHFIIVGNGEQKALIEKYAAEHGFLESLHITGWVNNSISYIELFDVAC
                     LLSRWEGFGLALPEYMMVGKPIIATNIDAIPNLISNGKNGLLVPVDDETAACEAVFKI
                     FSDKAMAARLTSEATSVVLEKYNSKRVASEHAVLFEMLVKKRG"
     gene            complement(45465..46017)
                     /locus_tag="NOB46_000043"
                     /pseudo
     CDS             complement(45465..46017)
                     /locus_tag="NOB46_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
     gene            complement(46486..47175)
                     /locus_tag="NOB46_000044"
     CDS             complement(46486..47175)
                     /locus_tag="NOB46_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI1057033.1"
                     /translation="MESEDLLSRISKVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYAAYRIRKEEPGSPIFFSHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTQIGKIIRAKSIDELPQLWNVLKGDMSLVGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSGRNDVSFHAMVDLDLEYITNQSLLNDFKLIIKT
                     IWIVIKPNGAY"
     gene            complement(47229..47993)
                     /locus_tag="NOB46_000045"
     CDS             complement(47229..47993)
                     /locus_tag="NOB46_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HCI1057034.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIVMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIQRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(48021..48719)
                     /locus_tag="NOB46_000046"
     CDS             complement(48021..48719)
                     /locus_tag="NOB46_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HCI1057035.1"
                     /translation="MARTQKQKATPTHAVSLITLTNPSSPIAEQYRTIRTNIQFASTT
                     GQQIKTIVVTSSGPGEGKSTTASNIAVVFAKSGQRVLLVDADLRKPVIYKTFQLNNAS
                     GLSTALSSSGSVADVIQRAPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPIVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDDGYYYGN"
     gene            complement(48732..49511)
                     /locus_tag="NOB46_000047"
     CDS             complement(48732..49511)
                     /locus_tag="NOB46_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HCI1057036.1"
                     /translation="MEETISLEEIFETLRKHLITIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVQERLKTEDNVKMTP
                     EQIKDAISINQSENSQMFSIQAISTSAMTAQQIANTTSQVFQENAKDVMNVDKISIVS
                     GAVANTTPISPNNKLNLVIGLMLGMMVGVVLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSEKELKAGIRKKGLAPTRPKVTNDKTASSRRSRSRV"
     gene            complement(49527..50471)
                     /locus_tag="NOB46_000048"
     CDS             complement(49527..50471)
                     /locus_tag="NOB46_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI1057037.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLNKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGVQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSILNALESNMKTDMSFDEMKKIALDYREAFDTIKQD
                     QMQGEGFMQDDISYQKVNDNELDRVKKELKEQMNLENK"
     gene            complement(50508..51284)
                     /locus_tag="NOB46_000049"
     CDS             complement(50508..51284)
                     /locus_tag="NOB46_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057038.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKIRAAYATKAQTVAQQMGYSNIS"
     gene            complement(51669..53744)
                     /locus_tag="NOB46_000050"
     CDS             complement(51669..53744)
                     /locus_tag="NOB46_000050"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCI1057039.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(53746..54663)
                     /gene="glyQ"
                     /locus_tag="NOB46_000051"
     CDS             complement(53746..54663)
                     /gene="glyQ"
                     /locus_tag="NOB46_000051"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCI1057040.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(55049..55861)
                     /gene="recO"
                     /locus_tag="NOB46_000052"
     CDS             complement(55049..55861)
                     /gene="recO"
                     /locus_tag="NOB46_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCI1057041.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            complement(56004..56903)
                     /gene="era"
                     /locus_tag="NOB46_000053"
     CDS             complement(56004..56903)
                     /gene="era"
                     /locus_tag="NOB46_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCI1057042.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(56918..57313)
                     /locus_tag="NOB46_000054"
     CDS             complement(56918..57313)
                     /locus_tag="NOB46_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HCI1057043.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            complement(57297..57773)
                     /gene="ybeY"
                     /locus_tag="NOB46_000055"
     CDS             complement(57297..57773)
                     /gene="ybeY"
                     /locus_tag="NOB46_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCI1057044.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(57790..59982)
                     /locus_tag="NOB46_000056"
     CDS             complement(57790..59982)
                     /locus_tag="NOB46_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCI1057045.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(60006..60977)
                     /locus_tag="NOB46_000057"
     CDS             complement(60006..60977)
                     /locus_tag="NOB46_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCI1057046.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            61683..63062
                     /gene="brnQ"
                     /locus_tag="NOB46_000058"
     CDS             61683..63062
                     /gene="brnQ"
                     /locus_tag="NOB46_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI1057047.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(63218..63664)
                     /locus_tag="NOB46_000059"
     CDS             complement(63218..63664)
                     /locus_tag="NOB46_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCI1057048.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(63691..63867)
                     /locus_tag="NOB46_000060"
     CDS             complement(63691..63867)
                     /locus_tag="NOB46_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCI1057049.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(64029..64457)
                     /locus_tag="NOB46_000061"
     CDS             complement(64029..64457)
                     /locus_tag="NOB46_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI1057050.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            64549..65409
                     /locus_tag="NOB46_000062"
     CDS             64549..65409
                     /locus_tag="NOB46_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCI1057051.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(65503..65853)
                     /locus_tag="NOB46_000063"
     CDS             complement(65503..65853)
                     /locus_tag="NOB46_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI1057052.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(65869..67596)
                     /locus_tag="NOB46_000064"
     CDS             complement(65869..67596)
                     /locus_tag="NOB46_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCI1057053.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            complement(67810..68736)
                     /gene="trxB"
                     /locus_tag="NOB46_000065"
     CDS             complement(67810..68736)
                     /gene="trxB"
                     /locus_tag="NOB46_000065"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCI1057054.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(68881..70317)
                     /locus_tag="NOB46_000066"
     CDS             complement(68881..70317)
                     /locus_tag="NOB46_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI1057055.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     ENEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(70314..71717)
                     /locus_tag="NOB46_000067"
     CDS             complement(70314..71717)
                     /locus_tag="NOB46_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI1057056.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            71947..72849
                     /locus_tag="NOB46_000068"
     CDS             71947..72849
                     /locus_tag="NOB46_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1057057.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(72890..74776)
                     /locus_tag="NOB46_000069"
     CDS             complement(72890..74776)
                     /locus_tag="NOB46_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1057058.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(74873..75724)
                     /locus_tag="NOB46_000070"
     CDS             complement(74873..75724)
                     /locus_tag="NOB46_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1057059.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(76047..77831)
                     /locus_tag="NOB46_000071"
     CDS             complement(76047..77831)
                     /locus_tag="NOB46_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057060.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(77831..79582)
                     /locus_tag="NOB46_000072"
     CDS             complement(77831..79582)
                     /locus_tag="NOB46_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1057061.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            complement(79724..79948)
                     /locus_tag="NOB46_000073"
     CDS             complement(79724..79948)
                     /locus_tag="NOB46_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HCI1057062.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            80199..81785
                     /locus_tag="NOB46_000074"
     CDS             80199..81785
                     /locus_tag="NOB46_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCI1057063.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            complement(82094..83869)
                     /locus_tag="NOB46_000075"
     CDS             complement(82094..83869)
                     /locus_tag="NOB46_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCI1057064.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(84080..84982)
                     /locus_tag="NOB46_000076"
     CDS             complement(84080..84982)
                     /locus_tag="NOB46_000076"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCI1057065.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            85261..87606
                     /locus_tag="NOB46_000077"
     CDS             85261..87606
                     /locus_tag="NOB46_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI1057066.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            complement(87769..88035)
                     /locus_tag="NOB46_000078"
     CDS             complement(87769..88035)
                     /locus_tag="NOB46_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057067.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(88028..88351)
                     /locus_tag="NOB46_000079"
     CDS             complement(88028..88351)
                     /locus_tag="NOB46_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057068.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            complement(88363..89619)
                     /locus_tag="NOB46_000080"
     CDS             complement(88363..89619)
                     /locus_tag="NOB46_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HCI1057069.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            complement(89616..90011)
                     /locus_tag="NOB46_000081"
     CDS             complement(89616..90011)
                     /locus_tag="NOB46_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057070.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            complement(90365..91366)
                     /gene="ccpA"
                     /locus_tag="NOB46_000082"
     CDS             complement(90365..91366)
                     /gene="ccpA"
                     /locus_tag="NOB46_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HCI1057071.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            91576..92679
                     /locus_tag="NOB46_000083"
     CDS             91576..92679
                     /locus_tag="NOB46_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI1057072.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            complement(92742..93356)
                     /locus_tag="NOB46_000084"
     CDS             complement(92742..93356)
                     /locus_tag="NOB46_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI1057073.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(93349..93798)
                     /locus_tag="NOB46_000085"
     CDS             complement(93349..93798)
                     /locus_tag="NOB46_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCI1057074.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            complement(93923..94861)
                     /gene="galU"
                     /locus_tag="NOB46_000086"
     CDS             complement(93923..94861)
                     /gene="galU"
                     /locus_tag="NOB46_000086"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI1057075.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            complement(94876..95901)
                     /locus_tag="NOB46_000087"
     CDS             complement(94876..95901)
                     /locus_tag="NOB46_000087"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI1057076.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            complement(95945..96775)
                     /locus_tag="NOB46_000088"
     CDS             complement(95945..96775)
                     /locus_tag="NOB46_000088"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCI1057077.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            complement(96790..97728)
                     /locus_tag="NOB46_000089"
     CDS             complement(96790..97728)
                     /locus_tag="NOB46_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCI1057078.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
BASE COUNT        28049 a        20978 c        16898 g        31938 t
ORIGIN      
        1 gagtatccta cggatttaaa tcatttgaga acatgagaat tagaatcttt ttgatcaatc
       61 aattaatcaa agtaagataa caaaaaatct gagccagaat gaggttcatt ctgacccaga
      121 tttgattttg tacaacccat cagtccttat tgacaaagag cccctttttt cattattatt
      181 tgattttcaa tgtcaaagca tttagagcta caactaccgt acttaacgac atcaagacag
      241 caccaactgc tggacttaat atgataccaa ttggcgcaag aattccggct gctagcggaa
      301 ttgcaagaat attgtaacct gccccccacc agaggttctg gatcattttc tttcgcgttt
      361 gcttggctag atcaagaaaa tgcaaaatat cttttggatc gctgtttgtc aatacgacat
      421 ccgcagaatc gattgcgata tctgtccctg caccgattgc catcccgatt gaagcacggg
      481 ctaaacttgg cgcatcattg atcccatcac ccaccatgat tacttttttc ccttggtcaa
      541 ggtatttctg gacaacagct tctttatcat ctggtaataa accgccataa tattcttcga
      601 tccctaaata atctgctact gcttgggcag cgtttttatt gtcaccagta agcatgacag
      661 gagtgatttt tctttctttc aatgttcgga taaattcttt tgcttctgtt tttactacgt
      721 cacctaaagc aacgattgca gctagatgat tttctaaaat caggaagctg atggtatttc
      781 cttgttcttg gtaaggtttc aataatgctt gttctacgtt taatccgaga cgctcaactt
      841 ctttttcatt aactattttc acttgttgtt ttttgactgt tgcctctagc ccgactcctg
      901 aaagattttt tagattttca gcttgataag gcttgatttc atgttctttc aaataattca
      961 taatgccaac agccaatgga tgattggcat tcgcttccaa ggctcctaga tattgaagga
     1021 tttcattttt attgaacgca tcatcaagta cttcgacacc cgttacagta aattttcctt
     1081 ctgttagtgt tcctgttttg tccagcatga tcacatctag atcattggct tgctccagtg
     1141 cattgcggtt tttcaaaagt aatccgtttt tagctgctat tgatgtggag cgagcaacaa
     1201 ctaatgggat agctaaacct agagcatgag gacaggcgat gataaagact gttaccatac
     1261 gttctaatgc attaggaaga tctgtcaaga acaaccaggc gatgaatgcc aggataccca
     1321 caattaatgc gacataaaac agccattttg ccactttgtc agataatgac tctagcttgg
     1381 atttttctcc ttgtgctttt cgcaccattt ccataacctt cgctagataa ccattttcac
     1441 cagttccagt tacttcgatt tcgatcgttc catccccatt gatagaaccg ccaatcactt
     1501 tgtcattggc ttgttttttg attcctcttg attcgccagt cacagctgat tcgtcaacaa
     1561 ttgtttcacc tttcaagatt acaccatctg ttggcatttt atcaccagac cggacgatca
     1621 aacgatcacc ttcgtttact tctttcaatg aaactgtctc ttcttttcca tctttcgtca
     1681 agcgtttcac tgattctggc agtaattctg ctagtttttg taaagcattg ctggcattcg
     1741 acacagcatt catttcaatc cagtgaccta gtagcataat aacgatcaaa gtagccaatt
     1801 cccagaagaa atccatgacg tgtgtatgtg gattgagcag atttgcgata aacgaataga
     1861 cactataaat atatgcaact gtaatcccca tcgcgatcag tgtcatcata gcaggacttt
     1921 tttgtttcaa ttccatctta gctccactta aaaatggctg accgccatag ataaatagta
     1981 tagttgctaa gatcaatacg agccaatcag aaccaggaaa cgttacttga aatggaaatt
     2041 ccattcccat cattggtgaa aaaagaatga ttgggatagc taggataagc gatagccaaa
     2101 atttttgttt gaaattcccc atgtgcatgg aatgatccat gccgccgtgt tcgtgatcca
     2161 tgtgcatcga atggtccatt tgtttgctgt ttgctatatc tccatggtta tgtcccatgt
     2221 gcatggaatg atccatctga ctatggtcat gtttcatctc catctgtttt tcatgagatt
     2281 ctgtactttc tttgtttact acttcttttt tatgctcatg ttttttctcc atatcgttcc
     2341 cattcatttt tactccatcc cttctcttac tttttcatgt gtcgatttaa gctcagggag
     2401 ttcaacaata cactgacgga actaaacgcc atcgctcctc ctgcaatgat tggattcaaa
     2461 aagcctagtg cggcaaaagg aataccaatc gtattataga caaaagccca gaaaagattt
     2521 tgtttgattt ttctcaatgt caacctagac aactcgattg tttgtgcaat ggatgccaaa
     2581 ctgctattca tcagcgtcac atcggctgtt tccatcgcaa tgtccgttcc acttcccatt
     2641 gccataccga catcagctaa tgctaaggcc ggtgcatcat tgattccatc gcctgccata
     2701 ccgacttttt tgccatcttt ctgaagtttt tctacgtagg ctgctttatc ctctggaagt
     2761 acttcagcaa agatatgctt tggatcaata ccaacttgtt taccaatcgt ttcggctgcc
     2821 agtttgttgt ctcctgtcag cataaaaaca tctaatcctt tattctggag ctgcttgatt
     2881 gcttgtttgg cttctagttt gatttgatca gccacggcaa tccacccgat cacttgcttt
     2941 tcatcagcta aaaacatgac tgtttttccc tgctgttcta attctaacgc gtgttcttgg
     3001 tattcatcaa atgataggtt caattcaatt aatcgtttac gtgtacccgc aaaatagcgt
     3061 actccattaa tcgtaccgct gatcccagca cctgggtggg ctgtaaaatc aatcatatcg
     3121 tatgttgctg cttcttgcag ttttccgtat tccacgattg ctttacctag tggatgttca
     3181 gaagcttgtt ctaaagtata aaaaatagat aggacttctt ttgaaccgac tagatctgta
     3241 actttgggct ttccttctgt aatcgttcca gttttatcca aaacaatgct gtctaagtga
     3301 gcagctgctt ctaatgcttc tccgccttta attaaaattc catttcgtgc accaacaccc
     3361 gttcctacca taatagctgt tggggtcgct aaacctaatg cacatggaca cgcaatgact
     3421 aatacagaga cactatggat caatgcgagt tgccaatcac cagtgatcaa acctgtagct
     3481 atgagcgtga taaacgcgat gactaatacg atcggaacaa aaatccctga gatccgatct
     3541 gcgatttttt ggattggggc tttgctccct tgagcatctt ccaccatttg aatgatttgc
     3601 gctaatactg tctgcttgcc gacttgtgtg acttccatgt gtagcagacc attcgtattg
     3661 attgtcccgc caaaaagcgt gtcatccgga ttcttttcta caggaagatt ttcaccagta
     3721 agcatacttt catctatcgc actgcttcct gaaataattc gaccatctgc tggaatctgc
     3781 tcaccaggac ggatgactag ttgatcacca acgactactt cttcaatcgc taacgtttct
     3841 tctttcccgt ttcttatcac ttgggcggtt tttgtttgaa gagacatcaa ttgtttgatt
     3901 gcattacctg ttttcgtttt tgctgtatgt tccaaatatt tgccgagcaa aatcagcgtg
     3961 atgatcatac tgctgctttc aaaataaaga tcttgggggt gtccacggaa aaatccgttg
     4021 taaatgctca atgcaaaggc agccgatgtt ccaattgcta ccaatacatc catatttggt
     4081 gctttcgtct tgattgcatg gtacgcacct ttataaaaac gagcaccgac ataaaattgg
     4141 acaggagcag acagcactaa ctggacgatt ggaaaatgaa aaaagtgaac aatcgccgca
     4201 tggcttccta acatcatagc aatcattgac aacatcaacg gcaaagtcaa aaccgtactc
     4261 aatataagat cgaatagcat ttttttcaaa tacgcttgct tttcttctgc aattttttgt
     4321 ttgtgggctt catcgtacaa aattgcacca taaccgatgt tttctacgct ttggattaat
     4381 ttttcagtgg tcgtcccttc atatttgaca cttgcttttt cagtggccaa gttgactgtg
     4441 gcattgacca caccaggttg tccgttcagc tctttttcga tcctagcaga acaatttgca
     4501 caagtcatac ctgtaatgac gaacgtatcc attttggttt ctgctgttgc catcaaatca
     4561 cctctgcttt ataacccaat ccattgattg cttgacaaat cttttcggat tgaacttttg
     4621 tttcatcaaa cttgaccgta ccgtttgctt ttttcaaatt tactttcact ttttgcacgc
     4681 cgtcaagtgc gcttactgtt tcttctactc ttgctgcaca atgattgcag ctcatacctt
     4741 cgattgaaaa ttgttgtttc attttttctt cctcctattg atgttgttta cattcacatt
     4801 gacctgggat acagttacat tcgatcgtat ctactggttg cttttgttcc agttgtttca
     4861 aaatctcatt gatatcttct tgagtcaaag tggcttcttc tactagatcc gcaatcgtct
     4921 ctccaatcct ttttgcacag atatgggaaa aaagattttc cgtcgcactg cgaactgttt
     4981 ccatctccga gacagctgga tgataaatga atttttttcc ttcttgttct gtccagatca
     5041 cttctttttt taccaaacgt cccagcaaag ttttgatcgt tgctggtttc caatccatcg
     5101 aatcagctaa gatctgcgtg atttcttggg ctgtcgtctg tccaagtgtc caaataacac
     5161 gcatgatctc ccactctgaa tcactgatct ttactggcgt tttgactttt tccatttatt
     5221 tcacaccttt cgtttacaaa tgtaatcatt agcttatgaa tacagattac gcttgtaaac
     5281 aaaaactgtc aattattttt gctctctatt ttcaatttag ttaaaaattc ttgtttctct
     5341 cgtcttgttt taaggatgat cagtttattt cttgcattag ctacttggat cagctgctgt
     5401 attttcggtt cattgttttc ttcaaaatgc cagataaaag ataaaaattc taagtattcc
     5461 ctgtttagtt tctctgaaaa tgattcaggc atatctggcc gagatttttt gtttatcttt
     5521 ctttttagag aacgccaaac tactcggtag atggcgagat aacgcggcac tttaagccaa
     5581 atgatcttat ctgcttcttt aatcctttcc tctaatgtag aagtataatt tccttcaaca
     5641 atccatgacg gattagatac cataaacgat tgctgttctt gcaaaaacca cttttttgcc
     5701 tgaatactgt agtctgttgt atgccataaa aggtctagcg gcagtagcgg aaagtcggtg
     5761 atttctttga tcttccttgc gagggtcgat tttcccgacc cactttgtcc aatcacgatg
     5821 atcttcattc ttctccctca cttctctttg gaatttggtt cgatcatacc acttataacg
     5881 ccgcaaaaaa acaagggact gtgacaaaag tcgtgtcaaa gtcccttgtt tcgaataaat
     5941 ggtgttcaat cagctgacct tcagcattaa ctcaaaaaac ggcaaaatat gaggagctat
     6001 tttttcgttt gttcctctaa tactcaggtc aaatcgctga ttttacaacc tcttccttaa
     6061 acggtgttct cctgccaaca cctcggtcac aaggcacaat agtcaacaaa catgagaagt
     6121 tgttttttga aattgctcct tgtgactcgg agttaaacgg caggctcact acctctttct
     6181 taaacggtgt tcaaaagctt gcatctgcgg taataagccc agcaaaacga aaaatatgag
     6241 gggctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
     6301 gattcacggt gttccagaag tagcttctgc gaaaaacaag ccgaaacttc acaaaaattt
     6361 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
     6421 tcttgtaaca agtatttcta ttttaaggct gaaccactgt ttctggttca gtgatttctt
     6481 tgtttttgtc tcgacgagca attgctggca agatcatacc taataagatc aagacaattg
     6541 gtgtgatgat attcgtgaat aattggaacc accatgcttt aggatcagca gtataatcta
     6601 cttttggcac cattcctagg atacatgcaa acgcagtgaa ggcaaagcac caagcaccaa
     6661 agataaaacc gatttttgga tttttaacaa atttatattc agaattgaat ttcttataag
     6721 ctttattcaa catcatatat gccaagaaca cccataggta acgcattggc atgacaactg
     6781 agttcaagtt cgtcaaccat tttactaatt cattcatatc tttgatacca aagatcggca
     6841 acaaaataat gattcctact agtatacctg tcagaagata accattcacc aatgtacctt
     6901 tacgattacg tttacgtagc cagtttggta caaattctgg atccgcatct gctaacaaga
     6961 tttttagtgg tgcatcaatt gaaaaggcta atgcggagat ttgtccaatc atgtttgtca
     7021 atgcgtaaat gatcatcaat gagttaccga taccatagta attacctaaa atttgaaaag
     7081 cactgtatgc cccatttgcc atcaagtctt taggaatatt atcgctagca aacagcatac
     7141 ccattgcgac tgagcctaat acagcacaaa tccctaccat tgctgctaag aagatcatcc
     7201 ctttaggaaa ttcctttgca ggatttcttg tagagttgac ataaggggat attttttccg
     7261 ctcctccaac tgcaaatact agcatcgaaa cggttgtgaa ataactgaaa tcaaatgttg
     7321 gaatatatgt tttcacttga ttcatatgtg gtgtggcaaa ttccatcgtt ggattgatga
     7381 acggtgccgt tacagctaaa agaataaata agatcgacat gacgaacatc gctgttccgg
     7441 ccagtccgcc aatcactttc aaagtagaaa gtccttttgt tgataaatat aaaaaggcaa
     7501 gaaatataat aagtgaaata actgctacca tttgtactga catcgtattt acgatatttc
     7561 catttccttg gactgcccaa ccgccagcaa tcaggattgc ttgaggcttt tgtgccaaat
     7621 aaggaatatg gacgacccag taagtccaag cggcatagta tgccagtcgt ttattagatg
     7681 tcgtattttc gacccatgaa ctgacgcctc ctttactatc cttgaaggct gaccctaatt
     7741 gtccaacgat caatgcgtat ggaataaaat aaatggccaa aatcaatagc caagaggtga
     7801 caactgatac tccttgctga gcatagttat taactacatt ccccatgccc caaaccatgt
     7861 taaatgcaat taacgcaaca gtaaaccagc gtaattgttt gttgttcatt cgttctctcc
     7921 tttatgataa aaatttgtta tccagatgta atcatattca atttttaaca aacttacaag
     7981 acagtgttat tttatgtgtg tattctttta tttaatacac atcgtttttt catatttttt
     8041 ccatcaaaaa aataagttat tttcttttat ttcatttacc ttattgaatt tcaagctatt
     8101 ttgaattttc tgcaaaatta aaaacattag ttattttata atcctatcta ttttctttac
     8161 atttttcatt aagaaaagga tataaaaaaa agaggacgtt cattcgtcct cttcattgat
     8221 caacgtttat tttttacatg caagcttcgc atggcattca aaacagctaa tactgtcacc
     8281 ccaacatctg caaatactgc atctcccatt gatgcaaaac caaaagcacc taaggcaagt
     8341 accaaaattt ttatcccaat agcaaagaca atgttctgtt tgacgatttt caatgttttc
     8401 tttgctaaat ggattgcttc tgcaatcttc gatggttgat cattcatgat gactacatct
     8461 gctgcttcaa ttgcagcatc gcttcccaat ccacccattg cgattcctac atctgctctt
     8521 gctagcaccg gtgcatcgtt gattccatct ccgacaaatg cggtcttttt attgtttctt
     8581 tgtaagattt cctctaaccg ctgcacttta tcttctggaa gcaattcgct atatatcttg
     8641 tccacgccta cttgcttccc gatatgatca gcaatttttt tcgaatcgcc cgtcaacatg
     8701 actgtgttct tcacaccagc cttttttaat tgaaccaatg cgtctacggc atcttctttc
     8761 aaggtatctg caataacaag ataaccactg taactttgat cgatcgctag ataaagcaat
     8821 gtaccgattt cttgacttga aggaaaagag atttcaaatc tttccatcaa tttgtgatta
     8881 cctgctaata cttgtttgcc atcaacttca gctaagatcc cttcacctgc aaattcttgg
     8941 atattagctg ttggtaaaag cggacctgcg tagccttcta aaacagattg agcaatcgga
     9001 tgtgtagaaa actgttctgc actcgcaaca tattgcatga atatctttgg atcgattttt
     9061 gtatcgatcg tctggatcga aaagtcacct ttcgttaatg tgccggtttt atcgaatacc
     9121 actgtctcag tttgtgcaag caactccaag taatttgaac cttttactaa tacaccgatt
     9181 ttacttgctc ctccgatacc gccaaagaaa ctaaggggta cggagatcac taatgcacat
     9241 ggacatgaga tcactaaaaa tgtcaatgct cgatagatcc attcagaaaa cgccgctcca
     9301 gaaacaacaa gtggaggtaa aacagctaat aaaacggcca atcctacaac gactggtgtg
     9361 taatagcgcg cgaatttagt aatgaaattt tcagctggtg cttttttact gctggcattt
     9421 tctactaatt ctaataattt gctgatagta gaattttcat aagatttttc tacttgaact
     9481 aaaaatggtt tatttttatt gataaatcca cttaatactg tttcaccaac atatacagat
     9541 ttagggactg attctcctgt aagtgctgac gtatcgacta atgattctcc ttcgatgatc
     9601 gttccatcta acggtacacg ttcaccaggc ttcacaagta caaactgacc gatctgcacg
     9661 tcttcagggt tcacggtcat caatccttcc gtcgtctgca cgtgagctgt ttctggacgg
     9721 atcgccatca attcgcgaat cgattttctt gaatgactga ctgccaatcc ttggaaatac
     9781 tcgccgattt gataaaatag catcactgct acggcttctg gatattcacc gatcaacata
     9841 gcgccaatcg tagcaacaga cataagaaaa ttctcatcaa agatttttcc tttgacgata
     9901 ttcatcactg ccttcttcac tacatcatat cctatcagca gataaatcaa taaataccct
     9961 atcaagcgaa ttggttcatt aaaatcaaat aatagcaata aagcgatacc tgcaagggaa
    10021 aataaaatcc ggaacagcgt atttctctct ttttcatttc catgttcaga tactttttcc
    10081 ttatctattt ctgttacttt gacatctggt tctaattcct tcactacttt ttttatttct
    10141 tgttcaatcg tagccaaatg atcttcctct gcgtcaatcg ttagttttcc agaagtgaag
    10201 tttaccgttg cttccttgac tccattgatc ttctgaactc ctttttcgat tttcattgca
    10261 cagttcgcac aatctaaacc ttctaatctg taacttttca ttttaatgac ctcctcgcct
    10321 caacatatga atatctcttc ataactaatt ataaatgaac ggttattcat atgtcaaggt
    10381 atccgaaaga aaaaatgaaa aacatctgca tcggaaaatt tcttccatac agatgttttg
    10441 gcttattctt tctttttctt ttcgatcatt gccactgctc ttatccaacc cgcacttgcc
    10501 ttcttgatct tgacaggata gcaactaagt ttgaagcctg ttgctggcaa tttgtctaaa
    10561 ttcattaatt tttcgatagg acaatatctt ttttcaatcc ctgcaaaatg tccttcccag
    10621 atattcgaag ctccactacg ctttcaaaaa tatagaaaga gttctttaat gaaaattatt
    10681 tcaactttcc ataaacagta accccatata aataaaagac gtaaaagtca catggaagaa
    10741 cttatacagg agaacgcata gagtcaggtg aaatacatgt atcccacctg actctatgct
    10801 ttatctaacc tttattattc tcttttatac aatttctgca ccgaatggca tcaacgccaa
    10861 tcgagcaagt ttgaaagatt gcttggcaaa aggtatccct atgatcgtga tacatagaag
    10921 gatgccgctg acgacatgtg cgagagcaat tggtaggcct gaaacgatca gccagatgat
    10981 attaacaatc aatgacatgc cagactggtg ataaattact tctttgccaa aaggcgcaaa
    11041 agaaagggag gcgatcttaa aacattgcat accgattggg atacctatga tcgtgataca
    11101 ccaaagtatc cccgctgcta accagctaag accaccgatt agtccgccga atataaacca
    11161 gatgacattt cctaaacaac tcattgtatt tctccttcta ttactgtttt tgattaaaac
    11221 tgggcaaaaa atgattttat tcttcttttt ttagcttcca gtatcaaata ttctgcaaat
    11281 tttttttgga tttcttccgt attttctttt gttactaatg tgtgttggat tagttttcct
    11341 gatggtcgct gatccaatcg ttcttctgac tgttgcacgt ccgcttgcgc aaatccgata
    11401 atccgttttt cttttgttac agcaacgagc aatagtttat tcttatcatt taggtcagct
    11461 gccgtttttg cttttacgaa tgattctgga tgatcagtaa tcagctgatt gatttgaggt
    11521 agatcttctt ttactgccca ccgtatttcc atcatttctc acttttcttt cgctcatttt
    11581 tatctccact aaaaaaatcg actgcggcaa ttgcatctat ccagctttgt gcaatgatct
    11641 catgtccgcc aatcgttggg tggaccccat cttctcttgt atatttcgaa aaaccataaa
    11701 caatccctaa agcattgaat ataccatcta aaggaaccag caatgcgcca tattccttag
    11761 caagtttacg aacaatttgg attttagggt ctaagtcttt acgccagcca tgacggtcgt
    11821 cggttatagg aagtacaaac ggctccatca agatgatgtt gcagattccc actgtttgaa
    11881 gttcatttag taattttcga taaacggatt caaattgctg agcagatttc tcagttccga
    11941 atatagcctg atcgctagta ttatgccagg tatcattgat tccgatcaaa atcgatacat
    12001 agtcaggttg taaagctaaa caatcttctt gccagcgtac ttgcagatct gcaattttgt
    12061 ctcctcctat cccacggttc atgcattcaa attccatcgt tggatattgg gagattagtt
    12121 ttccggcaat caaaagtgga taacctttac ctagatcagt tgcttctgct cggtctcttc
    12181 ctgcgtctgt aatgctatca ccgataaata atatacgttt tttcatttgt caaaaactcc
    12241 tttttgaata aaacgatgat tttcttcctt atattatccc ataagcccta tcaagacgaa
    12301 agagaaaata tatgtataaa aaatgacacc agcctagtcc cttcaaacaa ttgaatgaac
    12361 gctcatcaag tgtctagttt tttatgctat ttttttctta acgtgccgga ttccccttga
    12421 ttccttcgtt gtttggtcca gagagatcga tcacacctaa gcttccgtca atcagaccac
    12481 tgatgacgcc atcagaacat atatttatag gctcatctaa gacttctagt aaatgtccct
    12541 ttactaatat ctcttctaga ttgcttggga tagattggtc ataactttat ctggtccgat
    12601 gatttcaagg gtgaattgaa cttacatatg gattattgca tgctgaaaat acggacctac
    12661 tccatcttcg aatgttacta ttagtttgtt ttcaggtgct agatgctgct ttatttcaac
    12721 agcagaagca tcatcaaatc agatttccat ttgaattacc ttctttgtaa atgtttgatt
    12781 gattgcgatt tcgttataga accttgtgaa tcaaatagca atttcttttg ctttcttctc
    12841 ttgtctgctg gaaacttcct ttatcccgta ttttaaaaaa agaactgcga gagttcgcag
    12901 ttctttttta gaataaacgg tgctctccgg ccaactcctc ggtcacaagt cacaatagtc
    12961 atcaaacatg aaaaactgtt ttttgaaatt actccttgtg actcggagct gaacggcagg
    13021 cgcacaacct cttccttaaa cggtgttcaa aagccagttt ctcggtatta agccaaattt
    13081 atgcaaaaat gtggaaagcc atttccacaa aatttttctt aatactcgaa actaaacagc
    13141 tttttcacaa cctctccact aaacggtatt caaaagctta catctgcggt aataagtccc
    13201 gccaattcaa aaacatgaac agctgttttt gcttggctgt tctaattact tgatgcagaa
    13261 cagctttttc atcacctctt atggataaat tcggttcaac aaacgtggga atggaatagc
    13321 ttcacgtaca tggtcgatac cagcaatcca agtgactgtt cgttcaagac ctagaccaaa
    13381 accagagtgc ggaacagaac cgtatttacg tagatcaaga taccatgaat attctttttc
    13441 atccaaaccg tgattacgga tttgttctag caagaaatca tagtctgttg cccgttcgct
    13501 tccgccaata atttcaccgt aaccttctgg tgcgatcata tctgcacaga tcaccacgtc
    13561 ttctcttgtt ggatgtggtt tcatgtagaa tggcttgatg gcttttggat agtttaggat
    13621 aaagacaggc tgttcgaatg aattcgcaat gaacgtttca tgaggtgaac caaagtcttc
    13681 gccccattcg atgtcatcaa atccattttt cttcagtaat tcgatcgcat catcataagt
    13741 aatacgaggg aatggcaatt ttgtataagt ttttaagact tctttgtctc gtcctagtac
    13801 atctaatgca tattcgcaat gatctaaaac attttgtact aagaatgcta catattgttc
    13861 ctgtacttct aaactttctt cttgatgagt gaaagccatt tctggttcga tcatccagaa
    13921 ttcgatcaaa tgacgtcgtg tttttgattt ttcagcacgg aaagtcggac cgaatgaaaa
    13981 gacttttccg aaagccatag cagcagcttc catgtataat tggccacttt gagataaata
    14041 agctttttga tcaaagtaat ttgtttcgaa tagatccgta gtgccttctg gtgcagaacc
    14101 agtcaagatc ggcggatcaa ttttgacaaa atgatgttga ttaaagaatt catacgttgc
    14161 acgaatgatt tcatttctga tctgcataat cgcatgttgt cttgaagaac gcagccataa
    14221 atgacgatga tccatcaaga agtctgttcc gtgttctttt ggtgtgatcg gataatcgtg
    14281 gctctcgctt accacttcca catttgtaat tccgatttca taaccaaatt ttgaacgact
    14341 gtcttcacgg atttctccag ttactaacac ggatgtttct tggtgtagat ttttagctgt
    14401 ttggaaaact tcttccgaca cttcgctttt tacaactaca ccttggaaaa aggctgttcc
    14461 gtctcttaat tgtaaaaatg cgatttttcc gcttgatcgc ttatttgcga cccaagcgcc
    14521 gattgttact gtttctccca catggttttt cgaatcgatg atttgaattt gttccacgta
    14581 tgactctcct tttatattcc ttgaatttct ttaggattaa ttttgacttt tactctcaat
    14641 aaattgcttg attctgcgta ccgcttcttc taacgtagcg cgatcagtag cataactcat
    14701 gcggacattt tctggtgccc caaagccttc gccagtcaca agcgctaccc ctgtttcttc
    14761 taaaagatct tctacccatt gtgtgacatt ttcatattta cacatgcgta gcgtttcttt
    14821 tacattagga aaaagataaa aagctccttg tggcttttca agagaaacac ccggcagttc
    14881 tgccacaagc gaatataacg tattcaggcg ttcttcaaag gcgttccgca tttcttccac
    14941 tgtatcttgc tcgcctttca atgcttcaac agctgcatat tgactgactg ctgtcggatt
    15001 actggttgac tgggaagcaa cagcgatcat tccattgatg atcacaggat ttcccaccgc
    15061 ataaccaatg cgccagcctg tcatcgcata tgttttagac acgccgttga tgatgatagt
    15121 ctgatttttg attgcttctg aaatcgttgc aattggagta aactcattgc cattataaac
    15181 taaacgacca taaatatcat cagcaactat caaaatatca ttttttactg cccattcacc
    15241 gattgcctgc agttcattct tgctataaat cattccagtc ggattcgatg gagaattgat
    15301 gattacggct tttgtttttt ctgaacgtgc ttgttctagc tgttcaacag taactttcca
    15361 gctattggat tcttcccctt tcacaaagac aggaagtcct tctgccagtt ttacttgctc
    15421 accgtaactg acccagtaag gcacaggaat gatgacttca tcttgcgggt caaggatcgt
    15481 ttggaaaagg gtatacaaag caaatttcgc tccgtctgtt acgactgttt gtgaaggttc
    15541 atagacaagt ccatagtttt tcttcagata atcaacgatt gcctgtcgaa gctctgggat
    15601 tcctgctgtt ggtgtataat agctagcttt cccattgcgg attgcttcga ttgctgcttc
    15661 ttggatgttt tctggtgtcg caaaatccgg ttctcccaca gtcaaactca gcacatctct
    15721 gccttttgct tttaatgcct tggcctttgc cgcagctgcc aaagtgacag acggttctaa
    15781 tcgttttgtt ctttttgata actccatccc attcattcct ttacctttta aattcccttg
    15841 attgtcttga cttcatctcc agattcaaag ccaatcaggt aataattcag tttcccattt
    15901 gtttcttttc ctactacttc ccacacaggc tgatcatcat acatccctaa agcagctttt
    15961 tcgatttgga tttcaggatg ggccgcagca attgtctgtt ttgcttcgtt ttcagtcagt
    16021 ccctttgttt gatccaatac ttttactttt tcaccagatt taggaatgat aacggcgatt
    16081 tcttttcctt tatcatttgt acctgtcagt gaaaagtatg tcttctttcg agtaaaccaa
    16141 taaaaatgat cggtttcctc aagatttgca tatttctttg cgatttctac tgcttctttc
    16201 ttcgcctgca ccgccggacg actggaacgc aagtaaaaaa tcgagctgat cacgatgacc
    16261 gctaataaaa atacgatcaa gccaagtaac acgcgattaa tcgttttttc ctttgtctgt
    16321 tttttcttca agggtcgtcg ctcctttatc ttcattcctt ttcattatag cagattttaa
    16381 ttatgaaaaa agacagctcc tctaacttcc ttcttcattt ttctttaaga attcatggat
    16441 atcctgatag atttcctcca tagctagctc tttgatcggt acttttttcg gtaatgcatg
    16501 gatgatccgt gcgccatatt ttgcagtgac tagtcttcga tccaaaataa gcaatacgcc
    16561 acgatctgtc tccgtcctta tcaagcgacc taatgcttgg cgtaacttca aagctgcttt
    16621 aggtacggat tcctggtaaa aaggattgat cccctctgat tctaaataag cgttcctagc
    16681 tttgaccatc gggcgaagcg gattatcgaa gggtaaacgt gtgactacaa cgatctgcaa
    16741 agcatctcca ggcaaatcta caccttccca aaagctgtca gcgccaaaca atacgctttt
    16801 ttctgacaaa atgaagcgtt tcaaaagctt ctcccggctt ccaccaaacc cttgagctag
    16861 tatttctcgt cctttttcta gcatagacag atgcattttc tgatagacct tctgcaaaac
    16921 atcatgagaa gtgaataaca caagtattgg ccgatcttct tgttcgatca gacctgtaag
    16981 tgctgtctct aaataatcga tatatgcttg attgctgact tgatggacgg caggtgcctc
    17041 ttttggcaca tagatccttg cctgtttctc ataatcataa ggagaggcaa tcactttaag
    17101 aggtgctgct tcaatgccaa gcctcttaga gagatagtgt cgattagggc cgatcttcag
    17161 cgttcctcca atataaagaa tacgatcata tcgaggatac caaacagtcg acggcaacat
    17221 agccgcttga aaatcatgga gatgaaaaat catctgctgc gctgtgttcc caggaacgaa
    17281 ccaatggatc aaatgatctc gccagtcttc cagccattga tccatcagca agtattgctt
    17341 gtctaattga tcaaataggc tatataaact tgctaaatcg atccgcatct ggtttgtcca
    17401 gctttcttgg ataatctcaa aagtcagacg catttgtgac tgtagctgct ggatctcctg
    17461 ataaaaaagc tgcaggtgat caatggctgt cccagattcc agtggcagct gatccaacat
    17521 ctcttttgtc atcatgactt cttctggata ctgtccgtta ggttgcttgc cgctcactaa
    17581 actcattaat ccttctgcca tacaaatctg tgcttcgcat agcgcagaaa gttcttctcg
    17641 ataaatcgat aaccagcgta aggcttcatg ttctttcggt aaatagcttt gtattcggtc
    17701 aaacagctga tttggttctt ctaattgctg gatttgttta tggaaatagt taatacttaa
    17761 tcgtttgtca tttacttttt cagcgatttc cggcaaatga tgtacttcat cgatcaacaa
    17821 aaatggacta gctggaagca atggttcttt tcgctgtgtt tcttgtacta aaaacgcatg
    17881 attgacaatc aaaaaattac tttgcctgat tttcttttgc aagaaacgaa caaagtcttg
    17941 ttcgtaaaat gactgatttc ttgctaaaaa tccaatacct ctgtgcgcga tatctgcaaa
    18001 gaatgaatgg ttcaaatttg ttaaatgtaa ttcatccaaa tcaccagtct tcgtttgcgt
    18061 cagccaaact aagaccgcca tttgatacaa agcatattgt ttttgttctg gcggttccac
    18121 aagtgtgcct ttaaaacgct gcaaatcaat atagtggcga tagcttttga taattacagg
    18181 ttgtatgggc tgatctagca attgattcag caatggaatg tctttttcta tgatctgctg
    18241 ctgcaaaact agcgaaacgg tactgatgac agcgggtttt tcaggtgtag ccaaataact
    18301 caatggcagc agataaccga ttgttttacc cattcctgta gctgcttcga tcatcaaatc
    18361 ttttgattca tcttttgtga aatggtcgta gaccgcattc atcagtctgt tctgttcttt
    18421 tcgatacatc agtgttttac caaacatttt ttcttttgct tgtttttttc ttggatatgt
    18481 ccgctcgcca taatggacgg atgtgaatag ttccacttct tttttctgca aagctagccc
    18541 atcgacgatt tctaatgagg gatcaagtgg ctctggtttt tctttcattt cttcaatcac
    18601 atgataaatg aaacgactcg tatccatacc tgtgtgtcta cttaatcgcg caatctgctc
    18661 taacgtgatg attggcaatt ttctcatccg ttcttcgatc agcaaaagaa gttgacctgt
    18721 cacttcggca tcactatctg cctgatgagg attctcatga ataaatccaa ggctttctga
    18781 caaatcagct aagcgaaagc ttggttccgt cggcaagaaa atttgtgcaa gttctactgt
    18841 atcgatgcct ggtatcttca aactaggaag tccgcatcgc atgagttcat ggttcaaaaa
    18901 attataatca aaataaatat tatgcgcgac aaatatggtg tctgccaaaa gattgtaaat
    18961 cgtttgggcg acatcttcga aataaggcgc tttttggacg cgttgattcg tgatccctgt
    19021 taaatgctgg atttgttttg aaatcttccg ccctggatga atatcgatcg aaaaacgtga
    19081 agtgatccga cctgattcaa tcatgacgca gccaaattgg atgatccgat cttcttttgg
    19141 attcgtccca gtcgtttcga tatcaacgac tgcataagtt cttggtttca aaatatcttc
    19201 ctcttctcct gcctctaatg ttcttttgaa attatactac aaagtgcaga aaaatactct
    19261 catcgctttt taaagaaaat agacaaaaac gcccagacac gcaaatgtct gggcgtttat
    19321 tttttagtat aggttaatta agctttagta acgtttgttg cttgaggtcc gcgttggcct
    19381 tcttcaacat cgaaagttac tgcttggcct tcttctaaag ttttgaatcc gtcgccttgg
    19441 atagctgaga aatgaacgaa tacatcgttt ccgttttctg cagtgatgaa tccaaatcct
    19501 ttttctgagt taaaccattt tactgtacct gtttccataa taaaaatcct ccttgtgtat
    19561 caacacatat tttgcaatta cttgaatggt gtatatctgg aagatgttta tttgaaacaa
    19621 gctaccacag attaccgaac aaaaactact cctatagtat atcataccgt ttacaaaaaa
    19681 gctagagttt ttcgactttt tttattaaaa aaagttttct cagcgattac ataaagtgaa
    19741 aaaccgaact tttttttaaa ataaacgaca tattgttcag ttggtgtttt tttgctctga
    19801 tgttcttttt taaactaaaa aaattattct ttctgactac ttatcggttc tgtttcaacg
    19861 gtcgaggctg gggaagattc tttagtaggt ctgatgttct catggtattt ctgatagcct
    19921 atgacagtta ccagaagaac aaggcaaacc aatacgacca acgagattag tttttctttt
    19981 ttgctcatat ctatacctca taaataacag gatgatgtcc atcatatttc tgagtatgag
    20041 taaaagcaaa agctgcagct gtagaatgta agaaatgcca gcaactttca taatcacagg
    20101 tcggacagta ccaaaagtaa ccaaatcttg gctgcaaaga ccgttcttct gtttcaggaa
    20161 tcgcagaatc aagatctggt gtctgtacat aaacattttt gtacagacgt gtgcctgtaa
    20221 taggaaaccg ctgtgtttct tcagcaaaaa ctggctgact tgttaaactt agggatagag
    20281 acagcaaaca ccataacagt ctttttttca taaagacctc cttatcgata agtttttccc
    20341 aattaaaatc atatctcaag aacgcccgtt attcacattt tgttcataaa tgatgttttt
    20401 tgtatcataa tcgtcaaaaa gaggtcgtga ccacgtcaca acctcttttt taaacggtgt
    20461 tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag aaataatttt
    20521 tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct tccttaaacg
    20581 gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat gaagagctat
    20641 ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct ctcatacacg
    20701 gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gcaaaatatg tgaaactatt
    20761 tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct cttttaataa
    20821 cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa aataaacact
    20881 tttccgccat taatgatcac atcatctgct aatgcattca acacttgacg ccgatcatat
    20941 tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat aaataaatgt
    21001 gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat gaatttctta
    21061 tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga cagcttcttc
    21121 gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat cgcaacgtct
    21181 gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc tggtagagca
    21241 aataaataaa tcggccattg ttctggattt tcgaaagaat ccttcaagta cgtatcaact
    21301 gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt tacgccatgg
    21361 aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa accgccacct
    21421 gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg tagagatact
    21481 tcttttactt gtttgttgct gacttcatac aatttcatgg agtcgcggtt caatcccaat
    21541 aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata aggaagatca
    21601 cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt ttggtcagca
    21661 gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc tcctaacaaa
    21721 ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt ctcaaaacgt
    21781 ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac atcttgatgg
    21841 gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc tgaagtcaat
    21901 tgtgacaata attctttatc cttttttgcc ataaacgtac ccctcctaaa aaaatcattc
    21961 ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa acgtatctaa
    22021 aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta tcttcataat
    22081 ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga taaactaaga
    22141 aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt attaagtatt
    22201 atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca gcctattcct
    22261 gtaaaagtac gtaaaaacga ccgctaacct tccataacgt gcgttcttat cctaaagttt
    22321 tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt agcgaaacaa
    22381 attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc tattattggc
    22441 tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag ctgaagatac
    22501 tttcaaagta aatgcaaaag cagcctttgc tgtagatgcg caaagcggta agattcttta
    22561 tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatta tcggtcttta
    22621 catcgtcctt gatcaagtaa aagaagggaa actatcatgg gatgataaag tttcaatttc
    22681 agattatgca gaaaatttga gtgtcacccc agatttatca aatgttcctt tgcataaaga
    22741 aaacacctac accgttaaag aattattcga ctctgcaatc atccagtcag ccaacgcttc
    22801 aatggttgcc ttggcagaaa aaatctctgg cagcgaagca aaattcactg aacgaatgaa
    22861 agaacaattg aaagattggg gtatcaaaga tgcaacgatc gttaatgcat caggactgaa
    22921 taactcttat cttggcgaaa accgaccaga aggtactgga gaaaacgacg aaaatcaaat
    22981 gtctgctcaa gatgtggcta tcgttgcccg tcatttgatc ttggattttc cagaaatact
    23041 ggatgtatct agcactacga cacaaatgtt tggcgaaaac acgcaatcac cagtagaaat
    23101 ggtcaactgg aactggatgc tcccaggatt cgtgaattat aaagaaggcg tggacggatt
    23161 aaaaactggt acgactgaac ttgcaggagc ctgtttcgtc ggtacgatca ctaaaaacga
    23221 tcaacgaatc atcactgtcg tattgaatgc agacggccat gcggaaaacc caagtgcccg
    23281 tttcaatgaa acagctcgct taatggatta ttgctacgac aattggtcag aaaaagagct
    23341 tggaaaagcc aatgcaagta tccctagtct aaaaaccatt gatgtaaaag acggaaaaga
    23401 atcaacagtg cccgttgtgc ttaaaagtcc tgtaaaagta tgggtacgga acgatatgga
    23461 tactggaaaa ttaacaatca caccaactct tgacaaaaaa caagtcactg acaatgagat
    23521 ccaagcacct atggataaag gaacaaaaat cggtaccgca acgatcacct tggcagaaga
    23581 taaattaggt tatctagaag acaacaacgc gccatccaca gaaatcatca cggataaaac
    23641 cgtagaaaaa gcaaatattt tcgttattgg ctggcgacgc gtcgcagaat ttttcggtaa
    23701 cttgttttaa ttgaacaaaa agaaaaaagc atctttccat gtggaagatg tttttttgct
    23761 ttttctagtt taaataacag cttttttcat ctattttcgt tatactgtat aagaaaaagg
    23821 agttgaattt atgaatctaa ccagagatct gatttttttg gttctctatc ttattggggt
    23881 attctccatc gtttattggc gaaaacagaa aaaggatcct tccttgttct tttacagcag
    23941 tacgtggaca tttgcggtaa tcttgactta ttttgtcgtg ttggaaattt tttattcgac
    24001 cttttatttt ttgattccct tagtgttttt cagtatcttt gccttttcct atttttcaga
    24061 aaagcgaagg ctgctgaatg gtcttttatt caatgttttc ctcattagtt ttggtatcta
    24121 cttgtttgtc ttgctatacg aaacacaaaa tatttttctt ggcggactga ttgccttgat
    24181 cacgatcccg ttactgcttg tctttctatt cggcatttat ggattgatcg tttttctttt
    24241 ttggaacggt gtcacagttt tacgtagaga gtcgcattca ttagctaatc ttttaacgtt
    24301 gatactagcc atttttctta cattgtttct tgtttttgac tttttcttgt taaaatattt
    24361 accacaatgg ataaatgctt tgtttttctg catcccattg atcttgatct atctatttat
    24421 cgtattctac aactttttga ctgtctcatt cttgtatcag ttcaaccgcc ctcgatacaa
    24481 ccaagacttc atcgttgtgt taggcgccgg gttgatcaat ggagaaacag tttctcctct
    24541 tcttgccaag cgaatcaata aggcgattgc tttttattgg gcacaaagcc gtgcgacatt
    24601 aaatccgcct atcctattaa tgtcgggtgg acagggagca gacgaaaaag taccagaagc
    24661 aatggcgatg aaacaatatg ccatggaaca aggaattcct gaaagagata ttcttgtcga
    24721 aaccaattcg acaaccactt tggagaatat gcgctattca aaggaaatca tggatcagca
    24781 aatgaaaggg ccctatcgcg cgatcttcag ttccaacaat taccacattt tcagagctgg
    24841 tctctatgca cgacaagcga aactgaaggc aaatggcatt ggggcaaaaa cagctttcta
    24901 ttacttgcct aacgcgtttt taagagaata catcgccatc ttgatgatga acaaaaaaag
    24961 acatatgatc atttgcggat tgcttttcgc aggttccgca ttcttatcac tgatcacttt
    25021 acttttctaa aaaaccaagg tgtgacaaaa catatgtcac accttgtttt tttcttttat
    25081 tctcttgacg attggcaaga atagtattcc ttttttgacg gctacttgct gtgcagaata
    25141 aataccgctg tttcctgaac acataaagct gatcaagcag atcataaaga agtaaacagc
    25201 agcttgtgaa ccaaataatt cgattcccat cacaaaacag gcaatcggtg tatttgtcgc
    25261 accagaaaat accccgataa aacctaatcc agcaagaaaa ggaacagaaa catggagcaa
    25321 aggcgctagt actgcgccaa gcgttgcacc aatctcaaat agtggtgtca cttctccccc
    25381 ttggtacccc gcacctaaag acaagaccgt gaagaataat ttcccaataa aatcataagc
    25441 atgtgcctgt ccattaaatg attcctgcag tatcggaaga ctcaacccaa ggtaacgttg
    25501 tgtttgcaaa atcaacgctg cggctacaac tactgctcca cctatcgtat ttcgccaaac
    25561 aggatgagga atccattgcg cataccgcgc ttttaaaaag acgatcgaac ggctgaatac
    25621 ccaaccaatc aaaccaaaag caatcccagc aacaaaaact ttgaagaaca gcaacatact
    25681 ccattcagga atcacaccca tttggtaatg tagatgagaa acaccatagc tttctgtcat
    25741 gaaatttgca aaaagcgcag caaagaagct aggaaagatt gcttctgttc ggactttacc
    25801 gattgccaac acttctaatc caaataatgt tccagctaaa ggtgtgccaa atacagaact
    25861 aaaacccgca ctgattccac tgataaccaa aatctcccgt tctgctttat ccaatcggaa
    25921 taaatgcgct atattatcag ctaatgctcc ccccatttga actgctgttc cttcacgacc
    25981 aacagatccc ccaaataaat gggtagtgat ggtcccaaac aaggtcaatg gaatgagccg
    26041 caaagggatc ttctcttctc ctccattccc ttgatcgatc actaagttat tcccacgact
    26101 agaaagaccg ccatgatacg cataaagata agcaaaaagc gcgccgctga ctggcaatag
    26161 ataaaatagc caaggatgtg ctagtcggat atctgtcacg aacgtcaggc tatttaagaa
    26221 aaaagcagac aagctcccca tgaatactcc gagaatcgct gtgaccacca gccacttcaa
    26281 catgtacatc aaaatacgca ctggactcgg taattgtttt tccataaaaa attcctcctc
    26341 aaataaaaaa acgcctacta aagaaagggg ctggccccag actttagtag gcgtcattag
    26401 ctatcttacg ttagcattta aaggcgaaca ccatcaccta ttcacttcca ttaaaagata
    26461 gcatattttt ctgtaaaaaa caataaaatt atcgttcttt ctttacacgt tcagcaaatt
    26521 catagaaagg agccaatttc gttaactgtt gattacattg atcactatca tgacaaatat
    26581 aattcccctt tttcgtatac gtgccatcag aaccggcttt cgttgtagaa agaaagagcg
    26641 agacattcga tgttttctga cagatcgcac agattccctt attaatcgtt ggtgataaag
    26701 taccgctgat cccttttaat tttccatctt cgtaataaac catgaatttt ttttgcgtcc
    26761 ctggatcatt ccaaccgatg tacgtatgtg cttgcaagtc gatttcattc caagcgggtt
    26821 gtttgagttt tttcactttt cggaataatt tctcgatttg tggtttgctc ggctgcataa
    26881 acggctggac gatttgcttc agctcctcca atgctcgttc tgcttgcgtt tttgtcagtt
    26941 ttacatctaa aactgtcgtt aaaaacgtat cgatttctga tggttcgtaa cctaatacat
    27001 cgcgaatctt ttcagctgct agagcctgaa ccgtttgtac cgtttttgag tcattgacag
    27061 atgagtacgc atttaataac tgctctactt ctctttttat aaaaaaatat tgatatggtt
    27121 tcattgtttg ttccatgatt ttaaagtcct ttcttctaac caaagtgcat actttgtaga
    27181 aaaaagtgat cttctgcaaa gtatgtgtta cctgaagatc ccggactctt ttaaataaga
    27241 tacgttttgc atcttatcat cacccccttt aatgttcatt cttctatgta catgattcat
    27301 tcgataaata aaagtaaacc gtatcttgag cagatagtca actgcaaaca gaaaaaggac
    27361 tgtgacaaaa gtcgtgtcaa agtccctttc tacaaacaaa cggtgttcca gaagtagctt
    27421 cttcaaaaaa taagccggaa tttcacaaaa atttgagaag caattttcgt aaattccttc
    27481 ttatttcttg aagctgaccc acttctgtca caacctcaat atggtctatt attggtttta
    27541 cctgttaaat cgaggattct tttccgaagt aacgttgcca tctcttacgc atacttgctg
    27601 acataggctg agcggcttct ttgactgcgc agtatttgtc tacgaatgtt acgatatatc
    27661 cttctttgta cttaggcggt gcaatcgttg cgccccacat gtgcttcaaa atgatatctc
    27721 gctcaagatc cgacaaatcg gtgatctttt ctgcattctt tacagcgatt cttggatgga
    27781 tatacgcatg tgtgccttca tcaaatttcg tcgtacgcca atcatagtag aacagatcat
    27841 gcaaaagtcc agcacgcgct gttgctttag cattgccacc ccattttttt gcgagcagat
    27901 aactatagta agaaacactg atggaatgct ccaaacgagt ggaatgaaca tgctgtgtgt
    27961 aattcgctaa ttttttcact gcttctgttt ctaaaagatc ttctacataa gacatatatt
    28021 cttcgtcttc acgccatttt tctgtcataa ttatcgatct gccacctttt tgaatttcat
    28081 tttcttctga aattgatcta agtataccac cagtgttcgg attattctag tcgccttgga
    28141 taaaatagcc aaagcttaat agttccttaa tcataaagaa aaatgataaa gaacaatccc
    28201 tgccgcaacc ccaacattca acgattccgc atttcctttc atcgggatat atacgttctg
    28261 atcagtcaaa gacaagattt cctgacttac cccctgacct tcgttcccca tgattattgc
    28321 gaagttatct gatttttcta ctttgtctaa tgcgtgtgct tcttcattta attctgtgcc
    28381 atacactgta aaccctttgt ctttcattaa aggaatcact tctgtcaaat ctttttgcaa
    28441 cacaggcaaa tgataattgc ttccctgcat gctgcgcagc acctttgtac tataaatatc
    28501 tgccgttcct ttgcctaata aaacaccagc catatcaaat gcatctgccg tacggatcat
    28561 cgtccctaca tttccaggat cttgtacatt atctaataac agccatcctc ctgaaaaatc
    28621 tggcgtgcct tcagccgtta acgccatcac tgctaagatt ccttgtggtg taggtagatc
    28681 cgatacagca tccatgacct catccgaaac tagaaaagta gaaatctctt tgtttgcggc
    28741 cagccagtct ccccattctt tcatgcctcg ctgtgtcaca aaaagttctt ttatttctgc
    28801 atcagacgac gcagcttctt cgatcagatg gaacccttcc aaaagatatt cttccttttc
    28861 ttcccgatat ttctttttat gtagtttttt taattctttg attcttggat tttttgctga
    28921 ttggatctct ttcacattcc tcacctcccc atgattatat catggaatag gtgcttgagc
    28981 ttgtttcatc ctaaaaaaat cggtatcatt aatttataaa ataggaaaga aaggtgacga
    29041 acatgcgcaa agttaaaatg aacgtccaag gacgcgtcca aggcgtagga tttcgctaca
    29101 tgaccaagat ggtcgctgat caactaggcg tgactggaac ggtaaaaaac gaagacgacg
    29161 gctcagtcac aatcgaagca atcggcaatg acgacatcat ccagaaattt attgaagaag
    29221 tcaagaaatc accgagccca agtggacgag tgcagtatgt ggatgtccaa gaagacccga
    29281 tgattgagga acgaaagaaa tttgatgtgg tgggataagg ttgtgaaaaa gctggtctgc
    29341 atcaagcatt aaggacaggt tgtgaaaaat agctctccat atttttcaac aggctggact
    29401 taatgccgta gatgcaagct tttgaacacc gtcaataagg ttgtgagaaa gtcgcttagt
    29461 tttgagtagt aaggagaatt ttgtgaaaat ggctttctac attttttcat aaaatttgac
    29521 ttaataccga gaaactgact tttgaacacc gtcgataagg ttgtttttga ggcgctttgc
    29581 ctcgagtatt aaggagaaac attttcaaaa tagcttctca tattttgtta ataccgagaa
    29641 actgactttt gaacaccgtc gataaggtta ttcttgaggc gctttgcctc aaaaattaag
    29701 gacagcagtg aaaaagctga tctatcactt gcagtgagtt catttgactc cgctttttcg
    29761 ggcagaaaaa aagtttttag tttattaaag taagaaagaa acacttggaa tcattctact
    29821 ttttcctagt atttctttct tgattttttg tctttttttc aaaatttttc gctacgtaaa
    29881 agaacgaata tttatatgaa atttctatga agttgattga attccatgcg cttttttagt
    29941 atagttaagt ttgtgtaaaa attatagaag aggaagtatt ctatgaataa atggaaaaac
    30001 tggttattgg gatccggact tgtcagtatc ctgctctttt tatctggctg tgtgcggatg
    30061 gattcaaacg gaaaccctga cacttcggga atcgtttatc gagtactcgt ccatcctatg
    30121 ggccaagcga ttacatatct agttgaaaat ttcaattggt cttatggctg ggcagttatt
    30181 gcaatgactg tgatcgtccg tatcatcatc ttgccactag gtattagtca atcgaaaaaa
    30241 acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac aagttgaagc agcccaacaa
    30301 aaattgaaag ctgcaacaac acgtgaagaa caaatggcag cacaagcaga aatgcagcaa
    30361 gtataccgcg aaaacggatt gagtatgacc ggcggaatcg gctgtctgcc tctattgatc
    30421 caaatgccga tcttctctgc cttgtacttt acggcacgtt atacagaagg tattcgggaa
    30481 tcatctttct acggcatcga tttaggctca ccaagtatgg tacttgttgt cattgcaggg
    30541 gtcgcttatc tgcttcaagg atacatctca acgatcggta ttcctgaaga acagaaaaag
    30601 acgatgcgta cgatgctgat cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg
    30661 ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc
    30721 atcacaaacg ttatgatgaa accacgtttg aaagcacaag tggcagaaga gttgaaacaa
    30781 aacccaccaa aacaagtcgt cactccaaga aaagatgtga cagaatcagc taaaccagct
    30841 gacagcaaac aagcaaccaa acaaatcaaa caaccaaaaa acagtacaaa caacaaaggc
    30901 cgcaacgcag gaaagcagca gaagcggaaa taaaaatata tgacaaaaaa ctgtagacaa
    30961 ataaaaaaat ttctttgttc tacagttttt ttgttacaat caaagaaaac gttcgctttt
    31021 cgaggaggga tgtataatga tgttcaaaca atcaatggat agtcgaatgg aagaagacaa
    31081 aatttcgcta gatgcacttg ttcctaaaaa tcatttagtc cgtaaaattg acaagttatt
    31141 gtcatttgat tttatttatc tcattgttga atcaacttat tcgaccatcg gtcgacctag
    31201 cgttgatcct gtcgtcttag taaaattagt attcattcaa tatttatttg ggattcgttc
    31261 gatgcgtcag accattaaat aagtttaaac aaacctagct tatcgttggt ttcttgggct
    31321 tagtttaatt gataaagttc ctcatttttc aacttttggt aaaaactatg cacggcgttt
    31381 cagagaaacc gatttgtttg aacagatatt tatcattatt ctggaacaag cagttgttgc
    31441 tagatttatt catgaagaaa ttttgtatat ggattcaact catattaaag agaatgcgaa
    31501 aaaacgtatt tttacaaaag atatggcaca taaagaagcc attttatacc aaaaacgatt
    31561 ggaagaagaa atcaatgagg caagaattgc cgaaggcaaa cgccattttg gttcaatcat
    31621 tcgtcaggag gtggtcgaaa ggaaatttag cgtcgcagat ccagaaattg gttattatgt
    31681 aaaaacagaa cgagaaaaac agtttgctta ttcttctcat actgtttgtg atgaaaatgg
    31741 ttttgtatta gatgtcatga ttacgcctag aaatctacat tacagccgaa tgctcgtgcc
    31801 acaaatcgaa cgtgttaaat cacgttatgg tgtagctgct gatgctgcgt acaaaacacc
    31861 ttggaacgcc aagtatttaa tcgaccgaaa actacgaccc acttttcctt atactcgacc
    31921 caaaggaaac aaagaacgtt ttaaaaagaa agattttgat tatgatccct attataactg
    31981 gtacctatgc ccgaatgatc aaacacttca gtttcgcaca actactcgag atggctataa
    32041 aaaatatgta tctaaatctt ttatttgtga aagttgtcca ttattgaaaa attatacaga
    32101 aagccagaaa caccaaaaag aaatacatcg acatatttgt gaagattact tagatgaagc
    32161 agaacattta cgccatacgg tgtacaatcg cgaaaaatat aaaaaaagaa acgattgaac
    32221 gcatttttgc agacgcaaag gaaaagcatg gagtgcgcta caccaagtat cgaggcttgg
    32281 aaaaaatcag gtgcatacga tgcttgtttt tgtcgcaatg aatctgaaaa aattagccac
    32341 ttggcagtgg gagcatatgt ctttatatct tttattatac aaaaatagac aaaagtatca
    32401 gtctacactc ttagtcaaga ggaaactgat gcttttatct acagtctgag agagtgggac
    32461 aatagtcctt tctccaaaag aaaacaagtc cgactttgat agttaatttt aaaatcggac
    32521 ttgttttttc ttctttacgt cttttcctct ccatgtattt ccctaatttt cttaaattta
    32581 acgccatgag tgccaagcca atgttaatct tggctccttg tttccctcgt aagtggaaat
    32641 ccgtttccga tagatcgaac cttctttttc ctctaaaaac tttttttaca ttctgctttg
    32701 aaataacgcc atgtattatt cactaaaatt tgtcggtttc gctcactttt tgctttcgta
    32761 cattgactac gaacagggca gcaccaccat aagccgcctg ccagttacct ctcactctta
    32821 ccgggtcttt cagaacaccc ggatgctcta acacatcact cggctaggct ccgttattga
    32881 agaagaaagc cccatatctt tccatggcat cctcggccag cttaagaagc tcctccatct
    32941 gttcggagac cttcctcaca tatatgggca aaggccatga agacctccac cagactgttc
    33001 atgaccttct tcagtgctgc gatcatctgc tctctcttct ccatggctta cacctactcg
    33061 acagaatcag cggcatcaga ggcaagagca tccttcatgt gctgtgccag gaagtcatcc
    33121 agctggttca tagaaaaatc gacacccttg ttcatggcct cgctgatttc catcagcttc
    33181 tggttcacct cttcctcaga caggccggtg cgctcacaga tggaatggag cagatgatcg
    33241 tgcatctctg ccatcttctg gtccatgtcg aatttttcgt ggcagcaatc tctgcgccat
    33301 gccttcggaa atacggcttc cccccctcat cagactgtgt gtttggttcc agctctttct
    33361 tccgggattc ttcgctctcg gaaatcggtc tgtacagtga acacacataa atattcttcc
    33421 tatgactggt atcactcatg gcttgtctcc tttatttgtt ttgtcgagtc ctacctcaaa
    33481 ggaggtctgg ccagcatata ggtgttcatc tgactgtccc tttcaaaatt agtgtcctca
    33541 tctatgattt cgggcgtttt ataactcctc cggacaaaat ttttgaaaaa atttgtcgag
    33601 ggcttaatac acctctttca taactgcaaa cgcacgcttc aaggtcttgg tgatttctgc
    33661 atgcgacatg cgcagatccc tcgcaatctg ctgctggttc ttgttcagga agtaataatg
    33721 ctcgatgacc tttctctgat taaaggttag cttctggatc tcttcttgca gacgcttacg
    33781 ctccatcttc ttaaaatcag tcggagcaat cttctccaca atgtcaggag tataggacat
    33841 catgcagtcc tgtgtgtagc tgtcctcgat ggtctgctct atgcctccga ggtatcttgc
    33901 atagttggat tccagacggt tctctgcatc atggtcatgt agatggtcca ctgatagtcc
    33961 atatactcct caaccaggat gaagctattc ttatcggcga accgatacaa cattccattc
    34021 atgcggtcag ctgtgaagat ggagtacata tcattgcgaa tatagaggat aaagtcgttg
    34081 cgatacacgg tcaacagaga atcgtccatc tagaactgag ccacactcac ttggcaccat
    34141 attatcactc agctaacgga agccgggctg ctttacgcct ttggtgctgt ccttgatttc
    34201 cttccatata ctgcttgccg agattgatga ttcttctgac atcgatcaaa gtaacaggta
    34261 atttagaatc ttccacaaac ctgattatct cctctactac tttcggctca atatcttcta
    34321 atgcgatcac gattttatat acctgctact tcacaataac atcctgaaca tcagatattc
    34381 gtccaaaata ctttaatttc gccaatccat ccccataatt agcaaatcct ggttcttcaa
    34441 gtagaatatc ctctttcttt cgatctttca catatccaat aatatttgca tctgcgtctg
    34501 gatctgataa catggccaaa ccatattctt tagccaggtt tccattttcc acaaccaaaa
    34561 ctcgagtatg ggacttgctg cctatctttt tcagtaaaaa ctgaaataca gcattcttga
    34621 cgagcaacaa aacgcacgat atgatccaaa ataaaagcaa tggccatttg gaaaagtatt
    34681 tcacattagc gatatataag tataagaaag caaggaagaa caaacttcca ataccggtta
    34741 acgatactat tttaaaaatc cgttttgata ctttctgaaa taggtcttat tcgttgcacg
    34801 aaaaatcctc aaaaaatctg caatcaaaat actatatagc gcagccatca tcaaatacgg
    34861 aactgacaac atattgatcc cgggagcagc ttctaaaacg tggtaacaaa taaacatggc
    34921 caatagatag gctacaaaaa tagatgctgc atctccaata cagtcaaaaa ctgtgttcca
    34981 aaatcgttcc ttgataattt cattgattct ccccttataa taatatcgaa tgctccaaca
    35041 tcggtcagaa tcatctcttc tgtctatcat tcgccacgta gaagttgttg gaaaagagtg
    35101 acaaccgttc aagacgaacg gctatattgt attaattatt ctgtgtatca actaaccact
    35161 caacaaattc acgcactgca ccattaccac catcatgttc agcgataaaa tctgaaattt
    35221 ctagaacctt tttaactgca tcgtgcggac aggccacaat accacctgca cttttaacag
    35281 gatgcataca agataaatcg tttatatcgt ctccaatata tgcaacagta cttagatcac
    35341 tagtaatctc aagcagtttc tctattttat tgtctattcc ctgataaaga atgttgatac
    35401 caagttcctt acatctattt tctaatattt tggaacgacg accagtgata ataataggct
    35461 caatattatg ggctcttaca atatcgtgaa tagcgcaacc atctttaata ttgaacgcct
    35521 tcataatttc cccacactca cccatatata tctttccgtc tgttagagta ccatcaacat
    35581 ccataaccag aaatttaatt tggctcatac actttccccc cctttcaata attgatagaa
    35641 atcttaaata cagctttctt tactttagct gattcattca ctcttatgca aggcatatga
    35701 gcatcctcag gagttagtag cagcagcttc cctccttcta agagtacaca attgccaact
    35761 attgaattac tgtaaaacac aatatccttg tcagctgaat aatctacttc aatctgtaaa
    35821 ttagatatag attctactac aatatactcg catcctaaga gaatacattg aatgtctaaa
    35881 tatttcaagt gagattcgta cattctttct tcaaatctat atatatcata ggactcaaca
    35941 ttcagataaa ttccattgga aagatcatat cgaccttctt ctaattccaa caaggaattt
    36001 tttataagaa aatatagact tctggaaatt caatttccat ttttttagac ttaacttttt
    36061 catttatctc ctttatgcaa caataccagc ttttacaatt tgctgccatg taatggtacc
    36121 aacaagcata ccttcatcat cgattatagg aagaatgtta atactattag cctttaaaaa
    36181 tctcaatgca tcgacagcta atttatcttt agtaaatact ttgggattag caatcatcac
    36241 atcatcaatt tctacagaat agatatctac ttttctctca ataattcgtc ttaaatctcc
    36301 atcagtaata atgcctttga gagttccatc ctgatcaatg actgaaacta tacccaaccc
    36361 tttattcgac ataacagaaa tagcatccat taacaatgtt cccgaattga ccattggaat
    36421 ctcattgccg tgggacatta gatcagacac tttaagtatt aattttttgc ccaatgaacc
    36481 tgcgggatga aactttccaa aatcagaatc tttaaatcca taaataccgc tagcaacaac
    36541 agctaatgca tcgccgtaac acaacacact tgtagcacta gaagttggag ccaatcccaa
    36601 atagcaagct tcctcaaact ccggtaatat ctggacaata tcagatgcgg tagcaagcgt
    36661 agattttgaa ttgcctgtta ttccaattaa agtagcccca atcattttaa tattaggaag
    36721 aattttaaca atttcatcgg attcgccgct atagctgata gcaattacaa tatccttttc
    36781 tgaaaccata cctaaatctc catgcatcgc ttcagcagga tgaagtctga atgctggtgt
    36841 tcctaagctt gcaaatgtcg ctgccagctt agcagcgata tgacctggct ttcccatacc
    36901 agtgataatg acttttcctt cgcaattaac aattgcatca agaatacgaa cgaaagtctt
    36961 cccaagacaa tctctcgttc tttttaaggc ctcaatttca atatcaaaaa ctcttttggc
    37021 ctctattatc ttatccattt tatttacctc ttcagttttt aatagcagct ggaggtcttt
    37081 cacatgttgt aacacagtac aaaatgtgaa agacttacca tacatttcta tgcaatgcaa
    37141 gaaaaattat ctaacggcat tgtatacttt tagtacacgc tctaataacc cctcaaattc
    37201 atccaagaga accatattcg gaccatcaga caaggcattg tcaggatcag gatgtacttc
    37261 aaagaacaaa gcatctgcgc ctgttgcaac agccgccttc gcaagaggct caacgttatt
    37321 tctattacct cctgtaacat ctccttttcc accaggcttc tgaacactat gcgtagcatc
    37381 cataacaaca gggtaaccaa acttcttcat ctcaacaata gatgtcatgt caacaaccaa
    37441 tgtattatat ccaaaagaag tgccacgttc gcaaagcata atgttactat tacctgcctc
    37501 cacaagttta ttaataacat ttttcatatc ccacggtgcg agaaactgtg ctttttttac
    37561 gttaattatt ttgcctgttt ttgctgctgc cactagtaaa tcagtctgtc tacacaggaa
    37621 tgcaggaatc tgaagtatat cgcatacctc tgcagccttt tctgcttgcc aaggttcatg
    37681 gatatctgta caaattttca atccataagt ttccttaact ttcttaagga ttttcaaacc
    37741 ctcttcaata ccaggacctc tgtaagaggt aatactagtt ctgttagctt tgtcgaaaga
    37801 agccttaaaa taataatcaa tatcgagctt ctccgtaatc tccttaatag tcttagctat
    37861 taacattaca ttttcttcgg actcaataac gcatggtcct gcaattaaca taagtctatt
    37921 catcttatag accttccttt cttaattcat cttctacctg ctgtatctgc tccggcgtat
    37981 ccacccccac ggtttgatat ttagtttcct ttactcgaat cttaaatcca ctctccaaaa
    38041 ctcgaagttg ttcgagagat tcagatactt caagaggcgt tttgggcatt gtactgtatt
    38101 tcttcaaaaa ccatgtttta tacccataaa caccaatatg tttaaaatgc agagaatttt
    38161 ttccatctct ttcgtatgga acacaaaaac gtgaaaaata tatcgcataa tcattgacgt
    38221 cattgattac tttaacaaca tttggattgt caagttcctc ctgaacttca atatgttttt
    38281 tcaaggttcc catataaact tcatcgttat caaagcaaga atacaaatct gctatcatct
    38341 ctgccttgat aaggggctcg tctccttgga tattaagaac taagtcttca tcccggagtt
    38401 gaaggatctc tgcgcactca gcaagacgat ctgtgccgca agtatgttta tcagaagtca
    38461 tcaaagccat tccaccaaag ctttcaacac agtcaaaaat tctcttatcg tctgttgcaa
    38521 catatactgc atctagcata gctgccttag aaacattttc ataaacccac tgaatcatgg
    38581 gtttactaga aatcatagca agcggcttcc ctggaaacct acttgatcca tatcgagatg
    38641 gaataatagc tattgtcttc atcggttctt tctcctttta agataatcca ttaacaactt
    38701 atctttcata catattagta aaatactata tagtaaaata cacaaaatta ctgtaatgaa
    38761 cgttgatatt actgaatttg ggagcttact actgacatat cctccgacgc ctcccataat
    38821 cagtgcacct atcaaatagt tttttacatt cgtaataatt gatgccattt ttaattctat
    38881 acagtttctt acttcataaa actgaattgc agtaactgta agttcagcaa atattgtacc
    38941 tattgcagcg cctatagctt ccaaatgtgg tattaaagcc aaattgacaa cgagattaat
    39001 cacagcgccc gtcataatag agaaggtata caccctttgt cttttcatgg gaatcaaaac
    39061 agcttgacca accacactag caaatccaat tatcaaaatc aatggtgata gtaactgaaa
    39121 taaggaaact gacttagcgt atccgtctcc aagaaaccac ggtataaaag tatttgcgat
    39181 tataatcgca ccaactacca ttggggcgcc tatgcaaaac acaaatgata ctgcattcaa
    39241 tacttctttt ctaattctat caatattgtt ttctttaacc gctactgcga tatgtggcaa
    39301 cataactgca ccaagagatg taatgactgt catcaacagc ttcactattt tttcaggctg
    39361 cgagtatagc ccaacttgga catccgtaga aaatattcct aatataatct tattaacata
    39421 cgtatagata tatactgccg ctgttggaag aaataatcct aatattggtc gaatatgggg
    39481 tgttatcgat atatcatgaa tacttattct tctaacatat tttggaatat gacaacataa
    39541 taatgcattc cccaacagct cagttccagc caatataact gagtacaata ctacatcatt
    39601 ttcatttttc accaataaga atatcaaaac aagaccaatt aacttaacca ccatacttct
    39661 gattgcagtt tttttgaaat cttccatccc ttggaaaaac caactgacat caaaaagatt
    39721 tgcaactaaa taaacagaca tacttattag taaaacagtg tatgaatgaa gagtagccga
    39781 aataagaata tatacaggaa aaacgataaa cgaagaaata atacggataa caaagatgct
    39841 ccaaaacact ccacttcttc tgatcttatc attctgaaca taagcaatct cacgttgtcc
    39901 atacatgttc gtacctaatt gagcaattat taccgctacc gatacaatgg cgtacgaata
    39961 attaaactcc ccaactccct ccgctttcaa tactctagat acgtatggag tcgtaataat
    40021 aggcagtatc ataaccaaaa tttggtaaca aagattatag gcataatttt tgatcaacct
    40081 attcatatta ctcctccttt atcttaaata taatttcatc ctgccttttc gtaaattctc
    40141 gtactaaaag gcaagcaacc acaacagaaa atatatttgt tatagaaaac gcgaaacaca
    40201 tctggcaata gtagaaactc atcactggta tgtaaaagaa gtatgccgta attagtatat
    40261 agtatttcct tcttcttctg tttttttcct tattaatgcg aatatgaata ttccaagaaa
    40321 aaatccaaaa aacaataaaa gtaaacacca gcatacctaa ccaaccaaaa tcagagtaag
    40381 gtcgttgaaa ccacgaaaat tcattccccg caaagttact atctccacca acatggatat
    40441 atgcgttttt aaattctggt tctataccaa acatctctac caatgaggta agactttttg
    40501 ccccccaatt caattctgga gaatatctct ggagatattt atccagcata tatactgggc
    40561 ttccgatata ataagtaata tagtctgaaa actctcttgt tgccgcagtc gagttaactt
    40621 ttgtaatacc tcttaatgca taaaatacag ccaaaatcgc tactgcaacg aataaagttt
    40681 ttcgcacaac ttgcataaca ggaactcgtc cacgaggcga tacatctgac ttcattacta
    40741 tgtatatcaa aaatactata gcaaaaagct taactaaaaa cacacggtta ccggatataa
    40801 acatacataa aatatacatt aatgttggaa acaagtattt tatatttgat aaaacacgtt
    40861 ctttgcatct aattacatta ttgataaata catacaaata tgcaaggttt aatcctgtaa
    40921 ttaaactgat gccaaatctt gcaataactg agttctgcgt ttcatctgac ttagctgctc
    40981 caattgcata taatcctaaa gtgctataat cgccttttct taatatttct accaaaagaa
    41041 caccaaagaa cacaacagat aatagtgcaa aaattaaatt taattgtctg ctagggtaaa
    41101 tttgtacata ttcaatctta tattgatttt gatggtaatt atccactctt ttttttgata
    41161 aatagtctaa gaataatata tacatttctg gtatacacat agctaagaac cccgtcgtaa
    41221 taaaccagag cgtcttcttg ctatattgca cattccaaaa ttcgatatta taaaccacac
    41281 agcatgtcgc caaaaaaaac aatgcaatcg cgataaatgc tggtgatata aaacatcgat
    41341 tagacaaaat atacattatt aaaattagta taaattcaac aatcaataat tgataaatca
    41401 tttattcttc tcctaatatt ttctttcgga gaatctccaa atattcgcat ccgaaaacca
    41461 aatctggctc catataattt ccttctcccc actcattcca agcctgaaga aatagtatcc
    41521 gatgctctgg ttccttgtct tgaacatacg aaagtgctcg gtctattgca tttccaaatt
    41581 tttctggagt actatcaaca tacactcttg catctttacc agatcgtggg gttcgatcta
    41641 atcttggaat caactgagga tgtacgcact ctctcttttc ttcttcacaa taaaaattct
    41701 ccattatctt atcatatgga tagagatttg ctgaaaaatt accaactgtc tttcgcatta
    41761 tgctcttaat acctcttttc cagtatcctg aaatttttaa ttcggcatat ctctgcatat
    41821 cagaatttat tgcgtcatat cccatatcaa ggaaacgctg aaatctatta tgcactgcta
    41881 catctgtcat agatgacaaa tcgaacttat tatcaacaga tgttactcta gccacaaaat
    41941 agataccttc aaatccattc tccttagcaa gtttattcca tagtgaaata aaatgagcag
    42001 aatctggaat agaatctgga gcaaaaacca agaataaagg tttaccatca acttttatat
    42061 atctatcatc cttcaatgcc ggaagaatag atttaaagtg aagtatatag tcttcatcac
    42121 caggatatgt ttgttccaaa aacacaacat cctttgtgaa atgctttgac ttttgccaag
    42181 ttttatttga ccatgaatga ttagcccaac cgagacaaaa aggaaagtca ggttctccgc
    42241 tctgtaacac ctcattaaat ggaagttcta gaattctctt accattgcca aaccaataat
    42301 gccaatagca aaaaccctca accccatatt tcttagccat ctcagcctgt tgttttctta
    42361 cttccgagat tcttaaatca tagaaaccta aatctgcagg aatctggggt tgataatgat
    42421 tcttgaatag aggtttagct ttagcaacat tagtccattc agtaaagcct tttccccaca
    42481 ttatatcgtt ttcacgaaca ggatgaaatt gtggcaaata aaatgccagt acccttgctt
    42541 ttttcattta actgcctcct ctaaagtaat acgatcaaac caattcagtt ttccgccacg
    42601 agttgcgtta tatattttta tgttattact ttcgcaaaac tctcttgctc ttatatatgc
    42661 ctgattcatt ccaacaatac ttgctattac ttcatttgca tttttgtctt caaaaaaatg
    42721 acttctaatg gtcttatctt cagacactgt tccatcagca ttataagtca gtgcataact
    42781 atgatccata ccaagaagat atattttttt atatcccata taaacagcag cttgaatcat
    42841 cgaataagta actgtttcat gcgatacaat ggatttactg atatcctcac taaacttaat
    42901 atttttgcca ccaacagatt gctctgagtg aatacatata gcatttggat tatgcattcc
    42961 tctaactctc caataataat ccccaatgaa catgtattct aagtcaatat catctaattc
    43021 gttaccagta tctgcatatc tatcctggat aaaataatat ttaggtctcc actgggtttt
    43081 atcaaaaatc ttaaaaataa gattagcagc aaaacaatcc ttatccttta ttaattccaa
    43141 atcctccatt gtgagacttg gaccattacc tacaataaaa caggtctcac ctaaaaattt
    43201 atttctcagt ttctcaattc tttgaatatt atctgtattc ttgcagaact tatcgtagaa
    43261 gtatttgttt tgaacatcaa ccacaaatct cattagcttt agaataggcg gaattctatg
    43321 aatcaccttt ctaattttta tatttaccat atttactcct tccgaattac aatatcaacc
    43381 aaaaattcgt tatctaatta aatgtttact atctctggcc tttctcacta atattcaatg
    43441 gagtgtcatc ttcgaagata tacccttcag ctgatgcatt acctttatat tcaccaagta
    43501 cctgtggcca ttcaatacca atctcaggat cattccaagc caagccgccc tcgtcatttg
    43561 cgtgatagaa atcatcacta gtacctttca caacgatatt cctttcttta ttaaactttt
    43621 atcaactacg ataattcaac ttttgatcga gtcctcatca atgatactct taattacatg
    43681 agtcaactga gtgctggaaa taccatctgt atggggaaga taaacaaatt caacaccggt
    43741 tcccataaac tgttcttcat atttttccta ctgaggattg cctttctaat cagaacccac
    43801 gaacattttg ttaaatttat atttctccca tgccgcatac ttatccttat cattttgagg
    43861 gacaaccata tcgacatact ttattgaatt tacaatttcg gctcgttcta catacggaat
    43921 aacaggtgtc ttatttttat cttactaaac cggttcatct gtactaacac cgacaatcaa
    43981 aaaatcacat tgtgcttttg catttcgcat aacattcaaa tgcccaatat gaaacatgtc
    44041 atatacaccc gtggtgtatt ctataacttt ttctttcata aatatctcct ttaactgtgt
    44101 atttcagagt aaaataggaa tctttctcat caatctgcat cacactctac atgtccaaat
    44161 aacatagacc gaaaagtcaa gaaagataat tttccagtct gtgatgaacc ttctctcttc
    44221 tacatacttc acatagagtt ccattcattc ttcgaaagat aaatcatttc gacgcgtaac
    44281 aatcattacc atcgaacaaa aacgttgaac cacatacaac aggcacattc ctgcggtaat
    44341 ttctttaatg ttttttctcc tgagtcttca cttaccccga tatagttaat gcgactcaaa
    44401 aaatttcttg ctttcatcgt taacctctct ttttaactaa catttcaaac aataccgcat
    44461 gttctgaagc tacccttttg gaattatact tttcaagcac taccgatgta gcttcggaag
    44521 ttagccttgc agccattgct ttatccgaaa aaatcttaaa aactgcttcg caagcagccg
    44581 tctcatcatc aacgggcacc aacaatccat tttttccatt gctaatcaaa ttgggaattg
    44641 catcaatatt ggtggcaatg ataggttttc ccaccatcat gtactcaggc agagccaaac
    44701 caaatccttc ccaacggctt aataaacatg caacatcaaa tagttcaata tagcttatcg
    44761 aattatttac ccagcctgta atatgcagac tttccaaaaa accatgttct gctgcatatt
    44821 tctcgataag tgctttttgc tctccattac caacaataat gaaatgggcc tctggtattt
    44881 tattttttac caatctagcc attttaatga atatttctgg agccttctgc ggactaattc
    44941 ttccaaccat acctacaaca aacgcatctt gtggtatatt caaactttct ctttttacct
    45001 ctccatgagc tttatttcta tatgcctcaa tgtctacgcc attaaaaatg acctgcaact
    45061 tatcttcgca acaaattctc tttttcagtg ctgattgttt ctcggcatct gatatacaga
    45121 taattttatc gcaaaacaga gcagctattt tttctatagc agtgtatagc attttcttct
    45181 taactgagca cctcatgttg aatgcccatc catgtggatt gtatacgcaa tagttcttca
    45241 aaccaatttt agcaacacgt gtaatggctc ctgctttact cgaatgtgca tacacaatat
    45301 ccggattata tttctttatc agctttctaa taattacgat tgcttttagg tcattgagat
    45361 caatttctct agtcaattta atttgcttaa atgagagcac aagatttgca taatccgtct
    45421 cgcaaaaatc ttgcgagcaa atcaatatgt tttcaaactt ttccttatcc aaatacttta
    45481 aaagcatgcg aatataacaa tctacgccac ctgcagcttg ggcaatgtgt aaaactctta
    45541 ttttttgacg catttctgtc ctccatttta cttatcataa caaacagtat atctcgaatt
    45601 accagaaaaa taatcttcca atcagcaaag aaaactctct tatactactt cacattgatc
    45661 tccatccatt ctttaaagga aagttcattt caattcagag caatctgcca ataatagcta
    45721 agatcaggct gtacatacaa ttgctgtctt tcatagcctc catactgctt catctttctc
    45781 agcaatccag atttgggacc cacgatattc atatcttcct tgaaaatatt ccaaatctga
    45841 ggagattcat catccacgaa cacgaaacga aacttataga acttgaacaa tttaccattt
    45901 cttccaactc tatcttgtgc gaaaacagga gtccgccgga tcatcaaaca caataactaa
    45961 cgctgtaatc agtatcacag gacacaaata gcaagtgtta aaatggaaaa tatgaatact
    46021 tctccaatat acccggacta gataactccc ttttgttcat aatccctcat actcatcaga
    46081 ttcaccaaac tttaccgttt atttttttca atagttcacc aaatgactcc atctaacaag
    46141 gtcaaatata aaaaattaac gcattttcat tatcttttag gcatttatta atggagatat
    46201 ttagtgtttt tataacataa taaatgctca atgagagcct atgttgggta catcaatatt
    46261 aaagtattca gcactaatat gtttaagatc gatattatat atttcataat tttgaaaatt
    46321 ttctttcata taggaaacat gatactgaat tgctttagtc acctttcttt ttttagattt
    46381 tctacaagtg attcaaaact tccataatta cagttattac ttttgaaacg ataatatgaa
    46441 catgtgtaat cttttttatc aacaatctat caattctatc ccttactaat atgccccatt
    46501 tggttttata acgatccaaa ttgtcttgat aattagttta aaatcattca atagactttg
    46561 attagttata tattctaaat ctaaatcaac cattgcatga aaactaacat catttctacc
    46621 actaacttgc cacaaacctg aacatccagg ttttacatac aagcgttgaa gatcatatct
    46681 cgtgtactca gctacttccc tttccaaagg tggacgtggg ccaactagac tcatatctcc
    46741 ttttaaaaca ttccatagct gtggcaattc atcaatgctt ttagcgcgga taattttacc
    46801 tatttgggtg acacggggat cttctttcat cttgaacatt gcgccttcta tttcattttg
    46861 atcaagtaac tcttccaatt tttcttcagc atctaaacac atcgaacgga atttatacat
    46921 tttgaatgtt tttccatttt taccaacacg tgtatggcta aaaaatatcg gactccctgg
    46981 ctcttctttt ctgattcgat aagctgcata gaacatcaaa ggagaagcta aaatcaaacc
    47041 aatgatgctt cctacaatat caatcattct tttaaaaaat aaatagatat atcgtttttc
    47101 aactttttct ttatccaacc aaacttgatt aggatgtact ttactaatac gagataataa
    47161 atcttcactt tccatacttt cagtcccttt cgctctctat tcatttcctt tttatctacg
    47221 aataaaaact aaaataaacc aaacttcttc ttttttacct cttcatatat tggataactg
    47281 atctcatccc cgttgatcag atcctttgcg acttgcttca tctgtactac tttttcctta
    47341 ccaaagtcct tggcaatctg ctcatagcac tcttttaagt aaaaggtgcg cttagagacc
    47401 ccatgggcat cagaagcagc catctgcacg agattatgtt tgaccatcgt tttggctgtt
    47461 ttctggatat ctttgccaaa taccccaaca taacttggcg cagtgagttg cgccaaacat
    47521 cccatatcta ggaacggaag caaatgattc gggtcttcgc gaaaatgcgc gttacgttct
    47581 ggatggacga tcactggtgt ctttcctagt tctaacaact caaaaaaaag ctgctctgca
    47641 tataacggca cttccagtgt cggaaattcg atcagaagat atgtatcatc taaatctgta
    47701 aataaaattt catctcgctg gatgtcttca atgagcgttc cggtaatacg tacttcttgt
    47761 ccttccaata acgtcaaagg caattgtctt ttctctaatt ctgcttgtaa cgaagcgact
    47821 agagaaatga cttgtgattt ttcattgctg tattttccat tattgtggtg tggcgtgcat
    47881 aaaatatgcg tgatgccttg ctgaatcgct ttttcagcca ttacgatact tgcctctagg
    47941 ttttccgccc catcatcgat tcctggtagg atatggcaat gtagatcgat catttctctt
    48001 gcctcctctc ttcttatttc ttaatttccg tagtaataac catcgtcttt gctgtgttct
    48061 gctccgttgt atacaacacc taggactcgt gcttgtacca tctccaacag ctcttttgct
    48121 ttagtcaagg attctttacg tgacgtattt tcacgtacca ccaataaggt gccatccgtt
    48181 tttgaagaca tgatctgtgc atctgttacg gctactattg gtggcatatc aaaaattacc
    48241 acgtcaaata actgtcttgc ttctgctagg atctgatcca ttcttggcga acttaacaat
    48301 tctgatggat tgggtggctt aggtccacta ggcaaaatcg acaagttctc gactggcgct
    48361 cgttggatca catctgctac acttcctgat gaactaagtg ctgtacttaa tccactggca
    48421 ttgttcagct gaaatgtctt atagatgacg ggtttacgta aatctgcatc gactagtaga
    48481 actcgttgac cagatttagc aaaaacgact gcaatgtttg atgcagtggt agattttcct
    48541 tctccaggac ctgatgatgt cacgacaatc gttttgattt gctgaccagt tgtggaggca
    48601 aattggatat tcgtccggat cgtacgatat tgttcggcga ttggtgaaga tgggtttgtt
    48661 aacgtgatca aactgactgc atgagttggt gttgcttttt gtttctgtgt tcgtgccatt
    48721 tttcttccct cctaaactct tgagcgactt ctgcgtgatg aggctgtttt atcgtttgta
    48781 acttttggtc gtgtaggagc cagtcctttt ttacggatac cagctttcaa ttctttctct
    48841 gacatttctg gaactgttcc taagattggg aaccctaatg tatccgtcac atatttttca
    48901 tctttcactg ttcgatcgag taattcaaat aagaatgcca gaactacacc taccatcatt
    48961 cctaacatta agccaatcac tagattcaat ttattatttg gcgaaatagg tgtcgtattg
    49021 gcaactgcac ctgaaacgat cgagatttta tcaacattca tcacgtcttt tgcattctct
    49081 tggaaaactt gtgaagttgt gttagcgatc tgttgagcag tcattgcact cgtgcttatt
    49141 gcttgaatcg agaacatttg tgaattttct gattgattga ttgagatggc atccttgatt
    49201 tgttcaggag tcattttcac gttgtcttct gttttcaaac gttcttggac ttcatttagc
    49261 actagatcac tgacgatcat atctttatac gtattgatca tttgcaagtt cgtattgaca
    49321 tcattgacat ttgcagtatc tgattgcggc agtgtcacaa tcaactgtgc ttgcgaactg
    49381 tattttggcg tcaaaatgaa aaacgttaca attcctgaga tagccaagcc agcaaacatc
    49441 gagatgatga ttgttatcaa gtgtttgcgt aatgtttcaa aaatttcttc caagctgatt
    49501 gtctcttcca ttttttctcc actttcctat ttattctcta aattcatttg ttcttttaat
    49561 tcttttttca cacgatcaag ttcattgtca ttaacttttt gatatgagat gtcatcttgc
    49621 atgaagcctt ctccttgcat ctgatcttgc ttgatcgtat caaatgcttc ccgataatct
    49681 aaagcaatct ttttcatttc atcaaagctc atgtctgttt tcatattcga ctctagagca
    49741 ttcaaaatgg attgatagtt gctgacacca tttagactca atactttttt tgctacgcct
    49801 tctacgatct ttctttggcg cccttgtcta ccgtaatcac catttgggtc ttcataacgc
    49861 atacgagaat aagataatgc ctgaaccccg ttcaatgtaa ttttaccgat tggaaagtca
    49921 tagccatctt gtgagaaagt gaggtcatta ttgacttcga taccaccaac tgcatcaacg
    49981 agttccttta gccctttcat attgatagag acatagtgat cgattgggat gtctacatat
    50041 ttttgtacgg tatccatcgc catggcagct ccgccgaatg cgtaagcgtg gttgatcttg
    50101 tcttttgtgt cacgacctac gatgtcgaca tacgtatctc gaggaatgct gacgatcgtt
    50161 gtctgtttgt cttcaggact gactgtggca accatcatcg tatctgatct tccttgatcg
    50221 acccgaccta aatctccagt atcaatcccc atcaatagaa cagagaaaga ttcttgtttg
    50281 ttcagatcaa ctggtttcgt tcgttctcct tgggttcgtt ccactgactc gtaagttttc
    50341 tcaatagaat gtgagagatc cagatataat tttgctccta ctcctacaat tgctaatact
    50401 aatacgataa gaactgctaa aataatcaga aatatttttt tccctcttga ttttcttctt
    50461 cgtcttgcca tagtttcctc cgtttgctag ctttgcttta attgttacta acttatattg
    50521 ctatagccca tttgctgagc aacagtttgt gcttttgttg cgtatgctgc gcgtattttt
    50581 tcattccgga tctgctctat ttgactgagc accgtcaaat attgatcgta agtagcggtg
    50641 gcagtcactt gaccatcctt caacatcgta tcgaataact gatctagttg cgtgacttgc
    50701 gcgatctgag tatcagcgaa tcctagatat tgcataacaa ccgttttcca aggactatct
    50761 ttaaaaaagc tcatattttc acgtacacga gcgacatctg cacttgtcac cttttctttg
    50821 atgacgacat cgtctacagc ttgctgccag tttgatacat ttttagtaaa taaatcgttg
    50881 acagctgtct ggatcttcag ttttgattct gcatcctcta actgcgttaa gactgctttc
    50941 ttttcttctt ggatcgcagc agcttcttta ggtaattctg attccttgat gtcataatca
    51001 tctgccgaaa gtttgataga agatagttta tgtgacaaat ttgaaactgt ttcttctgtt
    51061 atttcaggat ttaggaaaat tttttctttt gtactgtaca gcttatctac ttcttttgat
    51121 aaagaggtca cggtgtcttt ttgattggtg atggcagatt ctgcgtaatt gatccgttga
    51181 tgatgttgcc gctgattatt gaaatggtat ccaaacaagc aaatcacaat agcgcctgtg
    51241 cctaccgcca cagtagccaa taacttgacg aacggctttt ccatagattc actcctaaat
    51301 attgatgata gataaataaa gatgtgattc attcccatca gaatgagcgc tttttatttt
    51361 aaaagcataa ttaaactaat atattcatag aaatatttat aaacaggttt tccctatata
    51421 atcataccac aaaaagtttt cttgactagg gaaattccta atttaaaagt aaataaaaca
    51481 gtaacaagat catgattaat cgttttcatt tttatttcct ctcttttcat gagcattttg
    51541 aaaattcgaa caaagaataa aataacaaaa attattaaaa tagaattaat aacagctatt
    51601 tatatttata acaaaaaaac agagacacag cacgtttcgt gcatgctctc tgtttttcaa
    51661 acaaaagact attttgtgat gatttgatcc aagcttgcta atgacaaagc catggcagct
    51721 atttgactaa gttgtgttag tcggttctta cgtactgctg gttcatcagc catgaccatc
    51781 gtttgatcaa aataattttc gatcagtgga cgaagagcga caagctggtc gtagttttcg
    51841 tggatcgttt ggtcagcaaa acttgctttc attgcttcta ctgctttgtg taattctttc
    51901 tctgcgtcgt tttcgaacag ctcaggatct acttctgatt gtttttcaag ctgcgctttt
    51961 ttcgctaagt tcacgacacg tgtcaaagct tccattgaag gtttgaagtc ttcatctgca
    52021 agatgttgtt tgaacaattg tgctgctgca aatacttttg tcagatcttt ttgttccgca
    52081 ttcaaaacag catcgatgac atcatgacga atattcttcg ttgtcaataa ttggcgcaga
    52141 cggcctttga taaagtcgat cacttgttgt tgcccttctg ataaaccaat gccgaaacga
    52201 tccgtatctt tactgataac atcgctaatc gtttcttgca gaacagacaa aggaaaggcc
    52261 cattttttcg attcgatgat ccgaacgaca ccgtatgctt ggcgacgtaa ggcataagga
    52321 tcgtttgaac cgcttgggat catcccaaca gcaaagaaag aaaagatgct atctaattta
    52381 tctgcaatcg ctaaaacaga acctactgta gactgaggta gctctccttc actggatata
    52441 ggcatgtaat gctcacgaat cgctgtcgct acagcaggtt tctcgccttt cagcagagca
    52501 tatttttcgc ccatgatccc ttgcagttca ggaaattccc ctaccatgtt ggttactaga
    52561 tcaaatttat agatttcagc agctcgttgc agatccatca attcttcctc agatagtcct
    52621 acttgttcgc caatgatacg ggcaatgact tgtacccgtt gcattttctc atagatacta
    52681 ccgatttttt catggaaagt aacagttttt agtttttcaa cgtattggtc gattgaagct
    52741 ttcttgtctt cattataaaa gaattccgca tcttctaaac gagccgtcaa tactttttga
    52801 ttgcctcgaa ccacattttc caattttacc cgatcaccat tacgagcaga aataaaatga
    52861 ggaagcagca taccttgatc attccgtacc tcgaaataac gttgatgttc tttcatagaa
    52921 gtgactagta cttcttcagg aacagaaaga tatttttctt cgaagtcgcc agaaaagaca
    52981 gttggatatt cgactaaatt gttgacttct tctagtaaat cttcgtctag atcaataacc
    53041 caatgatttt tttcggctaa ttcattggct tgtgtaacga tcatttcttg tcttttttgc
    53101 ggagacgcaa tgacgaattg ttcattcaat ttttcttcat attcttttgc atgcgcaaat
    53161 gtcacatctt cgcctaagaa acgatgacct cgagaggctc tgcctgtttt gacatccaag
    53221 atttcgaatg ggattacttc gtcatctaac aatgccacga tccagtgaat agggcggata
    53281 tattcaaaat cgtattctgc ccaatgcatc gttacaggga aagtcaggct tttaatgaca
    53341 tctgctaaac ctgtcaatac ttctttggat tccttaccat gagtgtattt cgttacatag
    53401 acatattcca caccttttaa ttctctaaaa gtgatagcgt ctgtcgtcag accttgtccg
    53461 cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc aatttttttg
    53521 gctggtcctt tgacttcttc ttcactgtcc gcttgtcgtt ctggaatgtt tgttactttg
    53581 attgctaaac ggcgcggtgt ggaaaatgtt tcgatcgtat cataagtcaa ttggttttca
    53641 tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac aacatgagca
    53701 ggcatttctt ccagcccgat ttcaagtaat aagtcttttg ccatcttatt cagcctcctt
    53761 cacgttttct ggatttgctg tgtttttatt caacaaaggg aatcctaatt tttcgcgttc
    53821 tgccacaaag attttggcta cagcacgagc catgttgcgg atgcgagaaa gataaccggc
    53881 acgctctgtt acggatactg caccgcgggc gtctaataag ttgaatgtat ggctacattt
    53941 caagatataa tcatacgccg gatgaacaag attttcatcg atacagcgtt tagcttcttt
    54001 ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa aagaatattt
    54061 agaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat cagcccattc
    54121 taaatcatag acactttcaa cttcttggat ataagaagca agacgttcta atccataagt
    54181 gatctcagaa gttactggtt tacaaggcag tccaccaact tgttggaagt acgtgaattg
    54241 tgtgatttcc attccgtcaa gccatacttc ccaacccaca ccggcacagc ccatggatgg
    54301 gttctcccag ttgtcttcaa caaaacggat gtcgtgttct agtggatcga ttcctaaaag
    54361 gcgcaagctt tctaaataaa gctcttggat attctcaggt gaaggtttca tcacgacttg
    54421 gaattgatga tgctgataca aacggtttgg gttttcgcca taacgtccat cagctggtcg
    54481 gcgagatggc tctacgtaag cagcattcca tggttctggt ccgattgccc gtaaaaaggt
    54541 atatgggctc atcgtacctg ctcctttttc tgtgtcatac gcttgcatca gcatgcagcc
    54601 gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca attttttact
    54661 catctgtttt gcccctttca attttaaagc gttgctgtca aataagaata caggaaagaa
    54721 aacgacaaaa aatccctatg tctgattaca gacataggga cgaataattc gcggttccac
    54781 cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg cctcttcaaa
    54841 aatcgtttgg gtccggctcc cactctcccg aactcgctaa accacgtgtt ttttactgat
    54901 cttggtcaat gtacgtattc attttgcagt tttcttgttt ctataataga tcctctcagt
    54961 gaacgatcta tttgatctac ggttaataat agacggaact ccctgtgttt gtcaaatggt
    55021 tttgattttt tgttgtatgt ttcatttact attcttcttt tttaggtaga tctttttcag
    55081 acatgtcttt ctctgacgtc tttaatacgt gtgcccaaga cttcatttga tcaatgaact
    55141 ttttgctttt caaatggata ccgacatatt catcatacag ctggtcgatg agttcacgga
    55201 ttgcttgttt ggtttcttct ttcagatgga ttccactgat tttatcataa gaaatagctg
    55261 aaaacatccg aacgaaataa acagctcgag gatctgcatg ataacggtga tcatccatcg
    55321 accagtgtct ttcgcatatc acaccaccat atttggaaga atagtcaaat tttccttttg
    55381 tttccccaca tacgacgcag tgtgtccaga ttggtgcaat tccgaagcgt tgcagtattt
    55441 ggacttcaaa aatattcgtg atgatttctg catcatctcc ttggtccatc cgttgcagtg
    55501 cttgttgcgt aaactggaac aaatgcgggt cgtactgatg atcttcgatt gccgcatcta
    55561 ctagattcaa taaatatgtg ccatagccgc tcaaaaagat gtcttcttgg atgtgtcgaa
    55621 acgcgtggac atctttgaca ctgcttaaaa atgacaaacc ttcacttcga aaattcccga
    55681 tataaactgc ttcagtaaaa gggagcaaag ccggagctaa gggctgattt tgccgatgga
    55741 tccctttgat ataaaacatc attttgccag aagattccgt aaagattttg actaatttat
    55801 ctttttcttt gtaattacgg ctagataaaa tcaagccttt tgattctgca agctggctca
    55861 tattctccct cctaaaaaat aaatctggaa aagcagattc tgccgatcca gatcatttat
    55921 gttgcgatct tccgcagctt ttctcaacac gcggattttt atccagttta tttctatacc
    55981 taacttacaa gaagctcaga atatcaatat tcgtcttttc ggtagccgaa gtcttgcaga
    56041 tagacttttt tgtctcgcca gtctttttga actttgaccc aaagttctag aaagactttg
    56101 tctcctaaaa gattttcgat atcttttctc gctttcgttc ctacttgctt cagcattttt
    56161 ccgcctttgc cgataatgat ccctttttgg ctatctcttt cgacaataat cgtagcctgg
    56221 atatggattt tatcattctc gtttcgcttc atcgaatcaa caacgactgc gacagaatga
    56281 ggcacttcgt ctcgtgttaa aaacaagact ttctcacgga tcaattcaga aacgatgaag
    56341 tattcaggat gatcagtcac ttgatcatct ggaaaatatt gtgggccctc tggcatttca
    56401 ctgactaata catccatcaa acgttcgacg ttgtttcctt ctgtagcaga aattggaatc
    56461 acttgtgcaa acggcatctg cgttgaataa tcttcgatga ttcccaacaa ctcgtctgga
    56521 tggattttat cgattttatt gataatcaga taaacaggag aatgcacgtt ttttagacgt
    56581 tcaataataa aatcgtctcc ccgaccgcgt ttttgatcag cgctgatcat aaataagacc
    56641 gcgtccactt ctttcaacgc actgtaagct gcttctacca taaaatctcc taaacgatgc
    56701 tttggtttat ggattcctgg tgtgtcaata aaaatcaact gagcttctgg tgtagtatat
    56761 actccttgga ttttatttct agttgtctgc gccttatcac tcatgatggc aattttttga
    56821 cccacgattc gattcaataa tgtggatttt cctacattcg ggcggccgac gattgcgaca
    56881 aaccctgatt tatgttctgg catatacgtt ctccttttta attaaacaac aaatgatata
    56941 ttttagggac aaataaaatc aacccaacga tgacggaaaa acaagcggtc actaaaactg
    57001 ctccagctgc catatctttg atttttttcc caatcggatg aaaatgaaaa tccgtaaaca
    57061 tgtccacgac attttcaaaa acagtattga tgatctctac tatccatacg agaaaaacag
    57121 ctaaaagcag ccataaccat tctatccgat caagctggaa aatcacgccc ataaacaaag
    57181 cgaggattcc gaacgcaaca tgtttcctca tgttgcgttc ttcctcaaaa acggttttga
    57241 ctccttggac ggcaaattcc acggacatca ggaaatgttt gtttttctct acgtttttat
    57301 cttttaagtc cataggcatc taagatctct ttctgtaaac caaacatttc tttctcatcc
    57361 tctggtgtca tatggtcata cccgttgata tgcaagaatc catgaaccgc taaaaagcca
    57421 agttcccgat catacgaatg gccgtaagct tctgcttgct ctgcagcacg ttcagtagag
    57481 atcatgatgt ctcccagtac acgaggcaat ggattctctc catcttcaaa aatcactggg
    57541 atttcgtctt cgccctcttc ttccaaggca aaactgatga cgtctgtcgg tgcatctttt
    57601 ccacggtaat cacgattgat tacttggatc gctgcattgt ccatgaaagt aacagacatt
    57661 tctgtttctt ctggcaactc taaatatgat gctgcaaatt gcagcaagtc gtcgatttct
    57721 ttcattttct cttctgagac ttggtttgtt tcatccatga aagtaatatc cattatacat
    57781 cgcttctttc tattcttctt gttcttcttt tatcttctca acttccgatt tcattttagg
    57841 atatttgatc cgagaatgga aggtactgct taaaccgctg atcaatgatt tttctacttt
    57901 acggatttct tttaacgtca atccactgtc gtccaattgt ccatcggaaa tacgctcttc
    57961 aataagatta tggacaaaac tttcgatttt ttcgctcgtt ggatggtcca ttgctcgtac
    58021 tgccgcttca caactgtcag ctatattgac gattcctgct tcacggcttt gaggttttgg
    58081 tccaggataa cggaattgct cttccgtgac ttccgggttg cgttcctttg ccttaacgta
    58141 gaaataacgc atcagcgtgg ttccatgatg ctgtctgcaa atatcgatca ccatttgcgg
    58201 catattataa tcttccaata ttttggcacc atctgtcaca tgtccaaaga taatatgttt
    58261 actgtcttct ggcaataaga aattgtgcgg attttccgct cctgaaggca agttctcaac
    58321 gaaaaagctg gcgtgtttga tcttgccgat atcatgataa tagcaagcta ctcgagttag
    58381 taaagaacgt ccaccgattt ctgctacagc attagcactt agattggcta ccatcatgct
    58441 atggtgatac gtgcctggtg cttcttccag caactgtttc aataaaggat gattaggatt
    58501 gctgagttca tttaatacga tcacactatc atcattgacc atcaattcaa tataggggtg
    58561 cagacctatc gtcagcaaga atgagaacag tgcacctgtg aatccgcata ctagcgttaa
    58621 ccaagtcgtt gcatccccaa agctcattcc ttggtagata atcaaaatga catccatcat
    58681 cacaggaaaa ataatgaccc acatagcagc ggataaccct tgttctgaga tccgtttgcg
    58741 tctgacgatc gttgccatga gaccagaaaa tacataggac atcaaaataa ctgtcagaaa
    58801 gttcgtgcca atcgaatcat aaaaaatgaa aagtgcggat actgcttgaa aaataccagc
    58861 catgatccct gctcttcgat tcaagaaaaa gcttaaaaca agtggagcaa aagccgcggg
    58921 gtaaaacagc ggaatataag cagcttgttc tgtttggaag agttggaaaa atttcattag
    58981 tacgacgctt actgacattg ccgtcacgta gaaaagtacg tattttgttc tttctcctgc
    59041 attttggaat tgaagtgaat tataaatcag tacaccgatt tgaagcaaaa cagctaaaac
    59101 catggcaatg agtgggaaaa tagaagtcgt ttgattcgtc aatcctagta attccaattt
    59161 tttcatcgct gaagcatcaa tttgatttcc ttcgcgaaca ataatttctc cttggaagat
    59221 catcactggt tgtacagctt ctcgtgcaga ttgttttaat tcttctgtct ttttctcatt
    59281 caatacatca ttaactacaa tgccttgatc cactaagtag cgaatcattt gttgctgctc
    59341 tgttgtgaca ttcaaatatt gaatctgatc ttctgcttct tgtttaaaag cttccaattc
    59401 gctttcacga acttgtttac tcatctgttc gtcaatgagc ttcaaacttt catccctaac
    59461 cgtgtgaatt tccgtttcag tcatttcaaa tatcgtcgaa taaaaattgt tcggcagttt
    59521 ttggtaaaac gcaacgtttt ctgcattcac gttttcaaaa tttttcttca gtgtagcaat
    59581 ccgctcttct gtagtaggtt tcgggatatt ttcatcttcc ttcgccttat ctaccttgtc
    59641 attataagat ttgttgatgg tatcattcgt cttatcgatc aattcgaata attgcttgat
    59701 ccgattgttc tggtcatctg ccagatcttt ttgataagta tattctggag tcactgcttc
    59761 tgctgccagt tttcttcttt gttcggtttc ttccgtgttc tcaatcgttt tattcgcacg
    59821 gatactctct tctgctactt ggccttctct gaaatcattg gccttttgtt tgacactact
    59881 aaatgtaacg ccgcagacaa tgataaaaaa caagaacaga aggaaaggca atgctgcctt
    59941 tccgagtttt tcttgtagtt tctgcagtgt tttattcaac atgtgcttat cctcctaagc
    60001 aaagcttatt cttgatgaag atccgccttt tcataagctt tgatgatttc ggcaactaca
    60061 gggtgccgaa caacgtcact tgcttcaaaa ttaacaaaat cgattttttt gatttgcttt
    60121 aatgttcgtt ctgcatgaac aagaccactt gtcgtcccac gaggcaagtc tatctgactt
    60181 gtatccccat tgacaatcat ttttgattga taaccgagac gggtcaagaa cattttcatc
    60241 tgagcgactg tcgtgttttg tgcttcgtcc aagataacga atgcatcatc caatgtccgc
    60301 ccccgcatgt aagctaaagg tgcgatttcg atcacgcctc gttccatcaa tcggttcgta
    60361 tgatccaatc caaaaatttg gtataaagca tcataaacag gccgcagata aggatccact
    60421 ttttctttca gatccccggg tagaaagcct aggttttccc ctgcctccac agcgggccgc
    60481 gtcaaaatga ttttttgcac ttcgcctttt tttagggcag caattgctaa tactacggca
    60541 agaaacgttt tccctgttcc ggctggccct acaccaaata cgatgtcatg tttggctacc
    60601 gattcaacgt atttcttttg accgctgttt tttacccgta taggttttcc attacggtct
    60661 ttgacgatct cttcctcata catctcaaca aaataatcta atgtaccttt ttgccccatc
    60721 ttcaatgccg tcacaacatc tggcgtactt acgtggattc ctcgtttgat caattcctgt
    60781 aatgtccgaa tgactgaggc agccaaggaa atctgggatt gctcaccaat gatctgaatg
    60841 atttctccac gtgtatggat ggttgtttcc gttgtttcct cgatcagttt tatatgcttg
    60901 tcgtgtgcac ctaaaagcat gctgacatca tcagcagctg tcaatctaat ctctaaagaa
    60961 ctagactctt ccgtcaaaaa tagacatccc ctttttttcg attcattctt tcctatttta
    61021 ccatactcag aagaaactat atagcaaata agaaaaggtt gtaaaagagt cgtttaacca
    61081 tacgtaccaa gaaacgttaa aaaatagccg tttccattcg ctaaaggtct cgttttgata
    61141 aaaagaagct gagaatgtaa gttatatgaa agtggagaac aaaatattcc gtttcattca
    61201 gcaggtattc tctaggtatt tttcttgttt caaaaaaaga aaacaaaata gttaaaatat
    61261 tcttgcattt caaaaaaaac aggtgtatta ttacgtcaac aaataaacat acagcaaagc
    61321 gtcgaggaaa acagtaggct attcaacgat ttattcccag tgagtcatgt aagtgagaaa
    61381 tgacaataaa tcgaatagac gaacatcatt tccgagtcaa tgtcgaaaac gtagatcatt
    61441 gtggctgcct ccattatcag gctagcggat aactttatca aaaagcgtcc gtgaatgaag
    61501 aagctttttt aagcgaaaaa aggtggtacc gttctagaat ctagagccct tttcccaagt
    61561 ggaaaagggc tttttttata ttttaaggtg gtggttttca tggaatctga tattagtggc
    61621 attactaatt gctgcaacgt ttatatcgtc aatcaaaatg ataattattg gaggaaaaat
    61681 ttatggaaga aacaaaaact tattcatgga aacaactatt gatggtcagt tcacttatct
    61741 tcgggatgtt cttcgggtca ggtaatctaa tctttcctgt ccacttaggt caaatggctg
    61801 gcgcaaactg ggtcagtgct ggcgtaggat ttgccatctc gggcgctctt ttcccattac
    61861 tagctatctt agctgtagta gtgacaaaaa gtgatggtct gtatgactta gctaaacctg
    61921 tcggaaaatg gtatgctgcc ttgttcttaa tccttgttca tttgacgatc ggaccatttt
    61981 tcggtacacc acggacagct gctactgctt ttgaaatggc tgctaaacca tttttgcctg
    62041 aaaaatataa ttcattaggt atgtttttat tctctgctct tttcttttta cttgcttatt
    62101 tccttactgt ccatcccaca cggttggtca aatacgtcgg aaagtatcta aactccttgt
    62161 ttcttgcatt gttagcaatc atttttgtcg tttctttatt ccacccaatg ggaaatctaa
    62221 atcaatctgc tgcagatact taccaaacaa acgctttaac aaatggtgtc ctagaaggtt
    62281 ataacacggt tgatgcagta gccttgcttg ccttaagtgt cacttttgtc catgcagtcc
    62341 gtgaccttgg tttcaaagat aaaaaagtca cagaattaac agcaaaagct ggtagcctga
    62401 gcgttgcgct agaagtcatg atctattttg gtcttgttct tctcggtgcg atgagtttga
    62461 ataagatgtc tttatcagaa aatggcggaa ctgcactttc tcagatcact aatttttatt
    62521 taggtaactt cggcgctagc ttcttaggag tgatggtcac attaggtgtc ttcactaccg
    62581 ctatgggact cgttgtttct tttgcgcaag atttccataa actgttccct aaagtcagtt
    62641 atatgacatg gctgcggtta acgactttcg tctcttttgt cgttgcaaat gctggtttag
    62701 acaatatcat ccaatggtct ttaccagtat tgatgctttt gtatccattg tcgcttgcgt
    62761 tgatcttgct ttccttaaca gcaaaatttt tccaaaagac accatttgtc tatcaagtaa
    62821 cgatgttgtt tgctgctgtt cctgccgtat tggatatgct ggcaaattcg cctgctttag
    62881 tgagtcaaca aagagttgta gcaagcatgc tcgaatttta tcatcatcac gttccttttg
    62941 ctgcattagg acttggctgg atggtcccaa cgttacttgg ttacgctggc agcctactgt
    63001 tttattacgc ctatcgccta tcagggtata aacaagaagc aaatgaacta ccagaagaat
    63061 aaccaaatca aacacaattt aacataagaa atattaaaca ggaaaaaacc agctagatga
    63121 aagaatccta ttctttcgtc tagctatttt tttgttctct tttttacgcg cacaaaaaaa
    63181 ctgcggacaa tgattgtccg cagtttaaat gataaaatta agattgtaat agttctttca
    63241 caatggcatt tacttggttt ccatctgctt ttcctttgac tttaggcatg atcgcaccca
    63301 tgactttgcc aaattctttc attgatgaag caccagtttg tgtgattgct tcttgaacaa
    63361 gttgtcgaat ttcttcgtcg gaaagttgtt ccggcatgta tttttcgact atcacaattt
    63421 cactttttac tttttcagct aaatcgtcac gtcctgcttc ttcaaactca tgcaaagaat
    63481 cacgtcgctg tttcatttcg cgagacaaca ccgttaattc ttcttcttct gtcaagtcgt
    63541 gaccttcttt aatctgctcg ttttgtatag atgacttgat cattcggatg acttgtaaag
    63601 attccttatc tttcgctttc atcgctgttt tcatgtcatc gtttaatcta cttagtagtg
    63661 acacactacc aactccaatt catcacagaa ctagaatttt ttgcgttttc tagctgcttc
    63721 agattttttc ttgcgtctta cacttggttt ttcgtagaat tcacgtttac gagattcttg
    63781 taaagtaccc gcttttgaca cggaacgttt gaagcgacga agagcatcgt caagtgattc
    63841 gtttttgcga acgactgttt ttgacatgtt aattccctcc ctccgagctt aaaaagtaac
    63901 cgtaattgtt attgaaatat atctcaaaaa acaagactgt cctgtaaata ttatatctaa
    63961 tgctgttttg accgtcaagg aaatcttgct tttttttaaa attatcaaat gttattttat
    64021 ttaaatcctt attgacaatt ttcacatctt ccgaaaatct cgaatctatg cccttcgatc
    64081 gtacatccac cgagctgttc ttcgaaataa ttcattggac acatatggat ttctttcgtt
    64141 gttccgcaca ccgtacagat aaagtgatgg tgatggccga tttccccttg acagcaatga
    64201 aaacgaaact tcatctctcc atttaaatcg gtttcttcca gtaaatcgat ttctgcaaaa
    64261 tcatggagat ttcgataaat cgtatcgtaa cttactcctt tgaattcctg attcatatag
    64321 tcaaaaactt ctttagcgga tacgtagcga ttgcgcttca ctaaataagt taacaatgct
    64381 tctctttttt tagtatattt aaaaccgtta tttttcaatg tttctagtga ttgttcaatc
    64441 aatgtctgtt ttttcatgac ttattcctcc aaatcaaaat gattacgaag tacacattct
    64501 agagtatggt ataataaaca taaaaaaaat gcaagtgagg ttttatccat gtcttccgat
    64561 tctacagaaa tcgttacttt ttttgtcatc tctgactctg ctggagaaac tgcgacaaaa
    64621 ttagcgcaag ccactatggc ccaatatcct accgttgagt tcaatttatt ccgcagaaca
    64681 tttgtgacag atgagaaaac attgatgcag gcactgcaag atgcactaaa agaaaaagcc
    64741 cttgtcctgc acacattgat caatcaagaa ttgatcgaga tgacgcgttc tttttgtgaa
    64801 gaacatcaat tatttagttt tgatgtgatg actccgccga tatcagaaat cgagcgctta
    64861 actggtatca agcccattcg gcaacctggc gcccttcatt tattgaatga gaactatttc
    64921 aaacggatca aagcaatgga atttgctgta aaatacgatg acgggaaaga tcctcgtggg
    64981 tttctagaag cagatgtcgt tttgctaggc gtatccagaa cttccaaaac gcctttgagc
    65041 ttgtttttag ctaacaaaaa tttaaaggtt gccaatctac ctttgatccc acaagcacat
    65101 attcccaaac agctttggga gatcgatcct aaaaaaatcg tgggactgac gaataaccca
    65161 gatattttaa acaatatccg taaagaacgg atgcgctctt acggattaaa tcctgatact
    65221 gcttattccg atatcgaaaa aatacgagct gaactcgatt ttgcgaatga tctttatgaa
    65281 aaattgggct gcgtagtaat caatgtcgct tctttatcta tcgaagaaac agcttcactt
    65341 attttgaatg ctttagacct agaagatcat agttattatg gaactgaaac caccgaagaa
    65401 acagactaac agtttttctt gtctttttct taaaaaaact ggactgtgtc agcgaagaag
    65461 attcgttgat acagtccagt ttgtctctat ttgcacctat cgttattgat gttccacatg
    65521 tttgagcgtc tggttcaaaa tatccagtac gtgagaatca tcaagactat acaaaatcgc
    65581 ttttccctca cgatgggact tgacgacatg gttttctctt aataaacgca gttgatgcga
    65641 tacagcagat tgttccattt ctactgcttg ggtgattgct gtcacatttt gttccccgtc
    65701 tttcagatac agcagaattt tgagacgagt ggggtcactc aacattttga atagttggct
    65761 gactttctct acttttgttt tttgcgtgtc tggcaatcca ttcacctcca acttgaaaaa
    65821 agactgactt ctaaagttta ccactttttc catcagtctc aagttttttt attcttctgt
    65881 catttttttg ataatcgctt cataagcggc tactttttca gctgcgtctt ctgaagagtt
    65941 tccttttaca ccgatataaa atttgatttt cggctcagtt cctgaaggac ggatagcgat
    66001 ccagccattt tcttccagcg tatacttcaa tacgtcagat ggcggtgtcg ttagtttttc
    66061 tacgtttcct tcacggtctg ttctcgtcaa ctctttgaag tcttctgttt ggatgacttt
    66121 tgctccggca aattctgtcg gtgcttcttc acggaatttt tccatcaaag cagagatttt
    66181 tgcagaacct tcttgtccgc tcattgtcac agaaatcgtt ttttctgcgt agtagccata
    66241 tgtttcaaaa atcgtttgca agccgtcata caacgttttg ccttgttttt tatagtaagc
    66301 tgctacttct gctaataaga gcaatgcttg aatcgcgtct ttgtcgcgaa cgaaaggttt
    66361 aactaaataa ccgtaacttt cttcgaatcc gaacataaaa gtatgggaat gatcttcttc
    66421 aaattgttga attttttcag cgatgaattt gaatcctgtc aatacattga acatggtagc
    66481 cccatagtgt tccgcaattg ctgtaggcaa ttcgctagaa acgattgatt tcaataccgc
    66541 tgcattttca ggtaaagtgc ctcgcgattg gtgtgcttcc aaaatatatt gagcaaacag
    66601 ggctccgatt tggttccctg tcaatacttc ataggagcca tttggcaaac gaacggctgc
    66661 gcctaaacgg tctgcatcag gatctgttgc aatcagtaag tcagcgcctt ctttctcgcc
    66721 aagtcgcatc gcatactcga aagcagagtg ttcttctgga ttcggtgatt tgactgtagt
    66781 gaaatccggg tctgcgacag cttgttctgg aactagtacg aattgttcga atccagcttg
    66841 tttcaacgca cgttcgccca acatttttcc tgttccgtga agtggtgtgt acacaagttt
    66901 caaatcttta cccattgttt ccaccaattc atgatcaatc gttactgctt tgatttcttc
    66961 tagataagcg gcatccactt cttctccgat gatcgtgatc aatccgctat gttcagcttc
    67021 gtcgtcagat aatacttcaa cttttaacgg attgctgact tcacggacat atttcgtcaa
    67081 tgcatctgcg tctgcaggag gcatttgtcc cccatcttct ccgtagactt tatatccgtt
    67141 gtaagctgct ggattgtggg atgcagttac catgattccc gcaaacgtct tcaaatgacg
    67201 gactgcaaaa gaaagctctg gtgttggacg taaactttcg aatacataag aagggatatt
    67261 gtgatgtgct aatgttttgg ctgcttccat ggcaaattct ggtgattgat ggcgtgagtc
    67321 ataagcgata gcgacacctc ggcgttttgt ttcttcacct tgtgtatcca tgaaacgtgc
    67381 aagtccttct gttgcttgtc ttaccgtata gatgttcatt cgattgatcc caggtcctaa
    67441 gattccccgc atgcctgcag taccgaattc caacggtgca taaaaagcat cttcaagttt
    67501 ttcaggatct tcacccagat caattaattg tttttttaag ttttcttcta aattttcttc
    67561 atgtacccat tgttcataca cttgttccca agacatgaaa ataacacctc tttctgaaat
    67621 atggttctta ataagtatag cattcactta ttagatatga aagtacgagg tctaaaaaac
    67681 gcttaaatca agaaaggatt cttttatcaa gcacggttgc aagtattcgc ataaatcgga
    67741 ttcagtagat ttcacgcgaa aaaaaagagt aaaagaacaa ttgaaaccgt tcttccactc
    67801 tttttaaact tatgcagttg tttcttctaa agattccaag tatttataca cttgttgtcc
    67861 agcgatccca ccatcaccaa cagcagtagt gatttgtcgc aaatcttttt cacgaacatc
    67921 tccgatggca aaaacgcctg gtatattcgt cttcatttcg ttgtctgttg gaatccagcc
    67981 agcttcgttc gtcaaccctg cttctctaaa tggtgcagtt aatggatcca gtccaacata
    68041 gatgaatact ccgtctgctg ccaaatcaaa ctcattgccg gttttgacat tacgtgcttt
    68101 cacacctgtc actaccattt cattcccaac gatttcgtca acgactgtat cccacataaa
    68161 ggaaattttt tcattcgcaa atgcacggtc ttggatgatc ttttgtgcac gtaattcatc
    68221 tctacggtgg acgatgacta cttcagaagc aaattgtgtc aaatagatgg cttcttctac
    68281 tgctgagtct cctcctccga tcactactag acgtttgtta cggaaaaacg caccatcaca
    68341 aactgcacag taagaaacgc cacgtccagc aaattcttcc tcgccaggta cgcctaattt
    68401 acggtggata cagcctgttg cgataatgac tgtttttcct tcgtaagttt tatcttcaca
    68461 aataacttct ttgtggctgc cgtgatcctt gatatcttgc acgattccat aagcattttc
    68521 tgtcccaaat cttgaaacac cttcatacat cttataagct agatcaggac ccatgattga
    68581 atcgaaacca ggatagtttt cgatttctgc cgtattgttc atttggccgc caggggcgcc
    68641 ttgttcgatc atcaatacgg ataagtttga acgtgaagca tataaagcag cagtcatccc
    68701 agcaggacct gcgccaataa cgattacatc atacatatgt agattctcct ttacttaatc
    68761 aagtaagcat actttacagc caatgcgaaa aaaagtctat tgttctgctt gcgtttctcg
    68821 aatagcttta ttatactcga aaaatccgct gaaaaacaat agacttttac aaatcattga
    68881 tcaatcattc gaaagatttt ctccatttga atcaattact tttttatacc agttgaatga
    68941 tttcttcttc gaacgggcta atgtgccatt tccttcgttg tcacgatcga cataaatgaa
    69001 tccgtacctt ttcttcatct cacctgtacc agctgatact aaatcaatac atccccaagt
    69061 cgtatagcct aatagatcga ctccatctaa ttctactgta tctttcattg cctggatatg
    69121 tgctgccaga tagtcgattc gatagtcatc ttccacataa ccattctcat cgggcgtatc
    69181 gactgcacct aagccgtttt ctacaataaa tagtggtttt tgataacgat cataaatatc
    69241 attcatcgtt attctcaagc ctaatggatc aatttgccaa ccccattcac ttgcttccag
    69301 atatggattt ttgacagaag caaagatatt tcctgcagtc tgttccaaga gttcgttgtc
    69361 agtagtcgaa actcgagaag aataataaga aaaggagata aaatcaacag tatgttcttt
    69421 cagcaatgcg gcatccccag gttccatttt gatctgaatg ccatttcgtt ccatttcttt
    69481 caatgcataa gcgggatatt ctcctcgtga ctggacatca atgaagaaat aattttctcg
    69541 atctgatttt ctagaagccc aaacatcttc aggattgcaa gtgtatggat aatatgctcc
    69601 tgctgccagc atacagccta ctttgttctc cggatctact tcatgagcaa tcttcgttgc
    69661 gatggcactt gcaaccaact catgatgtgc cgcttgatat ttgatttgtt cttcattttc
    69721 tccttcttca aaatacagcc ctgcgcccat gaatggtgca tgaaggatca tattgatctc
    69781 attgaatgtc aaccaatatt tgacaagtcc tttatagcga ttgaagatga ctcggcacag
    69841 attttcataa aaaccaacga gttctctaga acgccacgca ccatattctt tgatcaaatg
    69901 catcggacaa tcaaaatgtg taatcgtcac aagcggctcg atcccgtact tttgacattc
    69961 tttaaagaca tcctcataaa atttcaaacc agattcattt ggctcatttt catcgcccat
    70021 tggaaaaata cgactccaag caatggacat ccgataagtc ttgaacccca tttctgcaaa
    70081 caaagcaata tcttccttat aatgatgata catatcgatc gcaatttttg ctggataaaa
    70141 atgatcttta tcaaattcaa acattttctt ttttccagta atgacaggaa aacggtcttc
    70201 tccgattggc acaacatcta cgttcgctaa cccacgtccg ccttcatcat aaccaccctc
    70261 gcattgattg gctgctgtag caccgcccca taaaaaatct tttctgaatc ccatcatact
    70321 tcctccatta catgtgtatt gcttgacaat tctcttgcca gttcatcttg gacttcgatt
    70381 ccttctgctt ttaaccggct gattgtttcc ttgaattgcg gtaaatactg ctgatgtgca
    70441 ataaacaact catccatgat ccgttttgct gtctttcctg atcgtataag cggattgatc
    70501 gtaaacgctt gtaaagctgt tccataatca ccagtcacgg ctgcttcgat cgtcagcaat
    70561 tccatattct tcattacttg caaccagcct ctttcagcag caggaaggga accaaacgct
    70621 acatttcgtg cgccttgtgc gccaacatag gcagtgactt ctactacaca atctgccggc
    70681 agatcaggaa cagctccatc attctttgta gacaccacga tctgtgtttc tttatttcca
    70741 tagatcgaag caatcgtttc acaggcagca tctgaataat aagcaccacc tcgtttttgc
    70801 aattgttcag gtttatgatc caattctgga tctttgtata attcaaacag ctctgcttct
    70861 gtttctttca cttgttgcgc tcttgtacca atcgtttgat attcttctaa agcatgttcc
    70921 aacatttctt cttcacggta gtaatagcgg tggtagccac aagggatcat gttcatttgt
    70981 tttaattgtt ctttgaaaaa cgggatgtca aagatatttt tcggcaatcc attgtcttca
    71041 tcgtataaac gatcaatcaa atctgctgtg cggtcatttc ctttattatc tgctactttg
    71101 tgccaatgga agtgatttag accggcaaac ttgtagatca gctcttcttt tttcttgcca
    71161 agcattgctg gttctgtcat cgtcgccatt actggcacat tgcataatcc gatcacttta
    71221 tcccatttgc catatctgat aactgcttct gtcaccatcc cgcttgggtt cgcgaaattg
    71281 atcagccaag catttggaca taaacgcttc atgtcttcaa cgattgccaa aaccactgga
    71341 acggtacgaa aagctttgaa tatcccgcca gcaccatttg tttcttgccc aatcatccca
    71401 taataactag ggatccgctc gtctttgatt cgtgcatcta attgaccgac acgaaactga
    71461 gtcgtaacaa aatccgcatc tttcaatgct tcttcccgat ccaaagttgc atagatcttg
    71521 acttcatacg gagaagcatc ccacatacgc tgagacatct gactgacgat ctcaagcttt
    71581 tcttttcctt cttctacatc tacgagccag atttctcgta tcggtaattc ctcatatctt
    71641 ttgataaatc cttccatcaa ctcgggggtg taactgctgc ctccaccaat cgtagcgatt
    71701 ttgattcctt ttgccatgtt ctcactcctt tgctttttac acttttatta tcttttttgt
    71761 aaacaaaaca aacaatagaa attcgtttct ttccagtaac atttacaaaa gttagtgttt
    71821 tctactggat ttttgtaaat atcttgtcaa aaaatgactt tattaagcta tataacataa
    71881 atccgtttac aaatcatttt caaaaaagtt ataatttacg taaaaaaact agaagaaggt
    71941 atctacatgt tattacgtga aaaaatcaaa gaaatctcct tttctccttc agaaaatgaa
    72001 gtgattcagt ttctcttaag cgattctcca gcacttggcg aaatgaccat ccaagagatt
    72061 gctgagcgat gttatgtcca cccgtccaca ctcatccgtg tagcaaaaaa aatgggtttt
    72121 gatggctggg tcagttttcg taatgctttt ttagctgaaa cagcctatct tgaagggaat
    72181 tttcaagacg tagatgcgaa tcttcctttt tccaccacag acggtattat gacgatcgca
    72241 aataaaatgg cttctttaga acagatgacg attcaagata cactttctct cattcatcat
    72301 gaccaactgc aaaaagccaa acaactaatg cttcaagcaa aaaaaatcgt gattttcgcc
    72361 agtaactcga atactttgat ttctcaagat ttcatgctga aaatgaagcg catcaaaatg
    72421 gatgtcacga ttgtcaccac ttttggtgaa tcgttctatg aagcgtacaa ttgcacgagt
    72481 gatatgtgcg ggattctgat ttcttatacg ggtgaaaaca atgtgatcct tcgtaccgca
    72541 gaaatattga aacaaaatca tgttccaatt ttagcgttga ccagtatcgg tgattcaacg
    72601 ctatcctcaa tgagtacagc cgctttgcga cttacgacac gcgaacgact gtattcaaaa
    72661 attggtaatt ttacgatcaa tacatcgatt tgttatcttc tagacgtgtt atatagttgt
    72721 gtttttgcag aaaattatca acagaattta gtccatctaa tttctgtagg acaaaaattt
    72781 gataaacgcc ctatcagctc agccatcatg aaagagcctt tcaattttga aaataaagaa
    72841 gtggactaaa aagaatagtt aagtctattc cattctttca cctaaccgtt caggtcagtg
    72901 cggtgataag tgcatcgtct ggcccgaccg tctccccttg attttccaaa atatccaaat
    72961 aatccatgta attggtgacg attacaggtg tttctaaact gtatccttcc ttttcgattt
    73021 tctttttgtc gaagcggagc aacagatcgc cttgtttcac tctttctcct tgctgcacca
    73081 agctttcaaa atatttccct tccaactgaa cagtatccaa tccgacatga atcagcaatt
    73141 ccagacctgt ttcagaaacc attccgattg catgtttcgt ggggaacagg gtcatgactg
    73201 ttccgtcaaa aggggcacgt acttctcctt tttcagggta gatcaagatt cctcgaccta
    73261 gtgttccttg tgcaaaagct gcatcctttg ctgctttcag tggagcgatt tgtccttgta
    73321 tcggtgtttt tacaatttct ttacctgatc ttttctgtct gtcatctgtt tcacctgctt
    73381 cctccttcca aaagaaaaaa gtcagcgcaa aggataccac catcgcaatg gcgatcccaa
    73441 tcaatacatt aatcacatct gttaaatcac catctggtct aatatagttg ggaattgtaa
    73501 agatgcctag tccaccttga ttccaagaag ttaaattcat taacccacta tacgcgcccc
    73561 ctaacgcacc accgacacaa gtaaaaataa atattttttt acgtggtaat gtaaacccat
    73621 aaatagctgg ctctgtaatc cccacaatac cagaaacaat ggctggtatt gcaattgctt
    73681 tgtcttttgg atttctaagc ttaaagtaga gtgcggtaag tgctgcagtt tgtccaaaag
    73741 acactactgc aacaggtgtc ataatatttt gccaaccatt cacagaaaat tgcatcaatc
    73801 ccattggtac gattgcccaa tggagaccaa acatcaccag aatttgccag aagaagccta
    73861 cgattgctcc ataaataact ggcgaaagtg ctaaaagtgt ttcaaatcca gccattaaaa
    73921 tatcagttgc gaatgtgaat actggtccaa cgagtaaaaa acctaaaggc attgtaataa
    73981 gaacggtgaa gaatggaacg aagaaattcg cgatcatctc aggtactaac tttttaattg
    74041 gtttctgaat ttggctagct aacaacacaa taaagataat gggaatgaca gaagaagcgt
    74101 agttacgcgc aatccaggga atgccgaata ctgtttgata aataggtgct tcaaaaatag
    74161 tgccagaaaa tatggtcgtt agtggtgctt ctgctgcacc actcaaagct tccagcgaca
    74221 agctaggatt cattaatgct gcgccaagca acatccctac gaattcattt actttaaatt
    74281 tacgggcagc tgttaaaccg ataataacag gcataaattg gaatacagaa tcaccgatat
    74341 tatcaaacat aacaaatgtg ccagaaccgc ggtcaaacgc gcctaagaag acaaggaatg
    74401 ctgtcagtcc acgaatcatc ccgccagcag ctaagatagc aaggaatggt tggaaacagc
    74461 ccgatattcc atcaataagc atatcaaacg gtctcatttt ttctgttgaa acagcctcat
    74521 caaaagtaag gtttcctgct tttataacct cttcaaacac gactggcaca tgattcccga
    74581 tgacaacttg atactgccct cccgctcgca ttaccgttac aataccgtcc atatttttca
    74641 agatctcatc atttgctttt tcttcgtttt ttaatttgaa acgaagcctt gtgatacaat
    74701 gtgtcaaacc attgatattt tccttcccac cgacattttc tacgattttt ctcgctaatt
    74761 cttggtattt tcccatttct attccctcca atatattagt ggaaggttta gccaactgaa
    74821 tgtcactacc cttatttcat acgttcttgt taatttatcc tccttttttt atttatttac
    74881 aacgattctc atgcactaaa cgcgcagtat ggatcgttaa atacattttt tcgtccgtgg
    74941 acatctggta gttgaacgtc tcggctaaaa agtctgctat tttctcaacg caaccaaacg
    75001 tatccttata ttttttttga ataacctgaa acaattcctc agaaacttct cccacttctg
    75061 atttttctcc atctaggacg cgtgtcagaa aaaaacgtaa gtgtgtgacg aatcgaaaaa
    75121 aatggactga atcttcatca aatgtaatct tatagtaata gcggacgata tttagaatat
    75181 cctgtattgt tatagtaaac aggtaggtat tgttttgttg gctttgaatg ccttgtgcat
    75241 tgactaaatg caatgcgata aatccggctt catcttctga taacttgatg tggtatttat
    75301 ccgagatttt cttcactgtt tttttcccga tggcatactc tttaggaaat agttgtttga
    75361 tatcatacag caatacattt ggtacaaata ttcccatttt gtgacgttcg atagccgtat
    75421 acaaatgatc cgtcaatgca atatacacag aatcattcaa ctggacttgt agagcctctt
    75481 ttgtatattc aatgatttca caagaaattt ctaagtactc aagaggaatc gcttgtgcca
    75541 attcttggaa ctgttgtgaa agcccgtcat ttgtcaactg aaattttttg tcgatgcatg
    75601 agtcaaaaat cgggtcaccc actttctttt tgaatgccaa accttttccc atcacgatca
    75661 tttcctgatt tctttcatcc ctggttatta cgacgttgtt attcagtact ttctcaatca
    75721 gcatgttttg ctcctttcca tgatatatag ggctgtattc aaaacaaaaa gaaaaaccca
    75781 aaaagccgtc catggaacca tgggagactc atcaggttta gcttgcatca ggcaatcact
    75841 atccaagttg tatcgttttc tttatattat cgaaagcaaa cgctttctta gtggctatta
    75901 ggcacttttg actagctgtc gtcgtctttt ttaaatcggg tgactacgcc actaacgctc
    75961 acagatgaag aatctgggaa gctctgtttt attttcactc tagcgcttag gacaaaatgc
    76021 tactatgcta ctgtcacaac ctctttttac acaccactgc tttgcagttt gtacatatct
    76081 gcatacaaac cattttgcgc tagaagtgtt tcatgattcc cacgctctac tatatgacct
    76141 ttgtctaaaa ctaaaatcaa ttctgcatcc cgaatcgtgg acagccgatg ggcaatcgca
    76201 atcgttgtcc gtccttgtcg catttttgcc aatccttctt ggatcaatcc ttcggtttca
    76261 gtatcgatat ttgctgttgc ttcatccaat actagtattt taggatctgt cacgattgtt
    76321 cgcgcaaaag tgatcagctg tcgttgtcca ctagaatagc tggcaccgtg ttcgatcact
    76381 tttgagtgat atccttttgg taattcatcg atgaacttgt ttgcttgaac aaactcagct
    76441 gcatggcgaa tctgttcgtc tgtgatagct ggattcatca tccggatatt tcctgcaata
    76501 tctccataaa acaagaaggc atcttgcaag accaatccca ttttcttacg taactcttcc
    76561 attggatatt ctcgaatgtc atgatcatca atcaagattt ggccttcata aaattcgtaa
    76621 aaccgcatca atacgttgat gatcgagctt tttccgcttc cggtgtgccc cactaatgca
    76681 acggtctcac ccggattagc gacaaaagag atattgttca atacattgtg ctctccatca
    76741 taagaaaagc ttacattgcg aaactcgatc ttacctgaag taatcgcttg atctgctcca
    76801 ggattttgtt gcggtgcata ttcttctgta tccatgattt tcaaaatacg actaccggca
    76861 accatcccat ctgtaaaggt gctcaaaaag tccatcattt gagacattgg attaaaaaat
    76921 ccctggacat aggtcgtaaa tgcatagatc agtccaactt ctacgggaga atgcaacgca
    76981 tcgatcccaa acaaagtcaa cgccaacgca atcgccaatg catagagaaa attgatgatc
    77041 ggacttaaca gaatcgaatt cgttttgatc atcgcatagc gcgtgtctaa atactcgttg
    77101 ttcacttgtt caaattcttt agctaaacga gcttcttggc gaaactgctg gataatacgc
    77161 atgccggaaa tcgattcatt caatttcgtg ttcagctgac ttaatttttc ccgcatattt
    77221 cggtaaatac gagaactgaa tttctggtaa taccagatga cgattcctaa aatcggcaag
    77281 aacaccaaag tccacaaggc aatttctcca ttgatttgaa acatggcaac gaaagaagaa
    77341 acgactgcaa agatcccagt caataccatc aaaaagacat accaaaattc aaatagcgtt
    77401 tctgtgtcat tcgtcactcg agaaacggtc gatcctgccg gtgtctggtc aaaataacgc
    77461 atacctagtg tatgcagctt ttcaaataat cttacccgaa catactgata ggtcttcaat
    77521 gaagccatgg aatacaaata ccattggaaa aaccaaatga tacttttgac tatgactcca
    77581 aacaagtaca caccagcaaa aaacaaaata acttgtgtcg tagctgactg tttagccaga
    77641 tgatcatcca taaaagtttg gatgatcctt ggcaatagga cattgatcac agacagggca
    77701 aacgcaaata agatagcaac gatgaacgtt cttctaaaag gtttggcgaa cttcatcagt
    77761 cgtttgatga tcttcttctg ttctttaagt ggaatcgatt ttgtccattc cgattgataa
    77821 ttttcatcca tcaggcctcg cctccttcta tcttcgcttc taattgctgt ttttcccaca
    77881 ttcgttcata ccagccacct aatgcaagca gctcgtggtg ggttcctcgt tcaatgattt
    77941 tcccttgatc gacaacaatg atttcttttg catgcatcac gctgcttaaa cggtgagctg
    78001 caatgatggt tgttttctct tttcttattt cttttaaatt atgcaagata gcttcttctg
    78061 ttttggcatc tactgcagaa agtgcatcat ctaagatcag caattcagga tttttgatca
    78121 atgctcgagc aatcgaaatc ctttgtttct gtccgccaga taaagagact ccacgttctc
    78181 caactaaggt atcataacct tttggcaatt ccttgatttc attgttgata aatgctaaag
    78241 aagccgcatg ctctacttct tcttctgaaa gttttggatt agaaaaacgg atattatctc
    78301 gaatggtcat cgaaaacagg aagtgatcct gaggcacata accgattgat cctaataaag
    78361 cattcaatga atattctttg atcgaacgtc cgccaaattg gattttccct tgataatcat
    78421 cgtattcacg catcagtaat ttgatgattg tcgtttttcc cgcaccagtt ttcccaacaa
    78481 tacctaatgt ttctccttct tggatcgcaa atttgatttg ttctaatgct ggtgattctt
    78541 ctttcggata gttaaaagag gaaatagcta cattcagctc gccttttgcc ggggtctgca
    78601 ctgcacccag ttgttccacg atatgcgtct tttcatgcaa aagttcatta acgcgatcat
    78661 aagaagcatt tcctctttcc aatacgttga acaatcggcc aatcgcaaac atcggccaaa
    78721 caagcatacc gatataacta ataaatgaga ccatctgccc aatcgagatc gtgccttcca
    78781 agacatactt tccacctaaa ataattgttg caacataaga cagaccgata atcaaggtaa
    78841 tgaatggatc aaataaggag tctaaaaaat tgactcgttt gtttttaata attgcatctt
    78901 caatcttttc ttcaaaatcc gcgagatctt ctttttcttg tccaaatgtt ttaatgactt
    78961 tgatcccagt gatactttct tgtgtcttat cattgatact agaaaaagct tcttgcgaat
    79021 cacgaaaagc atcgtggagt tttgacccca gcactcgtga agtaacggct agcaaaggca
    79081 gaggaatcag cgcaatcagt gttaagcgcc aatcaataaa caaaatcatc gcaatgatcg
    79141 ttgttccgcc cgtaatcact gaatctgcaa aggtcaagat tccagctcct gctacattct
    79201 ggattgcatt caaatcattc gttgcatgag ccatcaaatc tccagtccga tatttttggt
    79261 aaaagagatt gtccatttct gtaaaatgtt tgaatagctg ctgccgaagt tctttctcca
    79321 accgagctgc acttccccaa atattcgtcc gccagatata acgaaaaaga tattgtaaga
    79381 aagctgcaag gatcaatagt aagatccacc aagaaatgat ctttattgat aaattcttat
    79441 cggcgatctc atcaatgatg atcccaatca cttttggagg aactaactgt accaaggcca
    79501 ctgcgaatag ggagaaaatc ccaattaaat aatgtttctt ttcctgacga aaaaaccaac
    79561 ctaattttct aaaaatcgac attttactcc tcctttgtct ttatcaagag cataggattg
    79621 tctgtccttg tcttttttgc tgaatagtct gaatagtcta acaaattacg aaataaaaaa
    79681 cggactgaaa aaatcagccc gcaaaaagtc tttgggtcag aacctatttt ttcccttggt
    79741 tcttcatttg ctgcatcatc tggcgaattt tcttctcaga tggtttttgc cccattgaca
    79801 tcatcattga tcgcaacatg tcctcattaa cgggaggatt tttttctaaa tagtctttca
    79861 tatatttacg cgctaggaaa aagccaccta ctgcgccgat tagcaaagca ataatagcaa
    79921 taagtacgac aatacctgtt gataccatat aaatctctcc tttctatttc cgaattgctc
    79981 tcaatgattt attttactaa agtttattga aaaaagaaag gcgtattctt tagtttcatg
    80041 caaaaaatag tggttttttt agagaagaac aaaatttctt tcattaacca gcaagacacg
    80101 ccacgaaaaa aaattaggca taccgaatct ttttctttaa ttttttcttt ctgaggtgta
    80161 gaatgtaatc gtagataaat aggaaaggtg gttttttctt gaataatcaa tccaacaaac
    80221 aatttcataa gcatcgactt attgaacata caaatggttt atctttagct gaagtaaatg
    80281 gaacagtgga tgtaccaaag ggaaaaagtt tttttaaaac acttcttgct tactctggac
    80341 caggtgcatt agtagcagtt ggttatatgg atccaggtaa ctggtccact tcgatcactg
    80401 gtggacaaaa tttccaatat ttattgatgt cagttatttt gatgtctagt ctaattgcta
    80461 tgcttttaca gtatatggca gcaaaattag gaatcgtgac ccaaatggat ttggcccaag
    80521 caatccgagc acggacaagt aagacattgg gtgtcatttt atggatcttg actgaattag
    80581 ccattatggc aacagacatc gcagaagtca ttggtgcagc aatcgccctc tacttacttt
    80641 ttgatattcc attggtaatt gccgtattta tcactgtgtt agatgttttc gtccttttat
    80701 tgctgacaaa agtcgggttt cgtaaaatcg aagctttggt tgtctgcttg attttcgtca
    80761 ttttattcgt tttcgtctat caagttggct tgtctaaccc tgattggcac agtttatttg
    80821 ctggctttat ccctaacagt catacattct cagactcacc tgtcataggt ggtgaaactc
    80881 cgctgactgg agcgttaggg attattggtg caacagtcat gccgcataac ttatatcttc
    80941 attcagcagt ttctcaaact cggaagatcg atcaccaaga cgaagaagat gtagcacaag
    81001 cggtacgctt ttctacttgg gactctaata tccagttgtc aatggctttt ttagtcaatg
    81061 cactgctatt gatcatgggt gtcgctgtat tcaaaaccgg ttctgtccaa gatccttcct
    81121 tttttggtct gtatgaagct ttatctgatc catcagctat gagcaatggt atcttgattg
    81181 ctgtagcaaa atctggtatc ttgtctactt tatttgctgt agcacttctt gcttctggcc
    81241 agaactctac tattactggt acgttgaccg gtcaagtcat catggaagga ttcatccata
    81301 tgcgtatccc gatttggcta agaagactag tcacacgatt gctttctgtg attcctgtat
    81361 tgatttgtgt tttgtttaca agtacaaaag gaacgatcga agaacatacc gctttgaata
    81421 acttgatgaa tgaatcccaa gtttttctgg cttttgcatt gccattctcg atgattcctt
    81481 tactgatgat gaccaatagc caagcggaga tggggagccg attcaaaaat tcatttgttg
    81541 taaaacttct tggctggttc tctgtgatta gtctgactta cttgaactta cgaggattac
    81601 caggtcaaat cgaaagtttc ttcggcgagc aagccacctc agctcaacta gcattggctg
    81661 atcaaatcgc ctatgtaatc attgttcttg tccttctcct gttggcatgg acgattggtg
    81721 atttatataa aggaaacaaa aaatatgaac agcgtttgca agaaacgata gaagaaatcg
    81781 aatagaaact gattctttta cacaaaggag gttgtgacag aagtgggcag cttcaagaaa
    81841 taagaaggaa tttaagaaaa ttgcttttca aatttttgtg aaatttcggc ttatttccga
    81901 agaagttact tctggaacac cgtgtatcag aggttgtgaa aaagctgccc tgcatcaagt
    81961 aataagaaca gccaaacaaa aatagttcct catattttac gtttggttga gcttattacc
    82021 gcagatgcaa gcttttgagc accgtttatt cggaaaaagg aactgcgaca agacttttgt
    82081 cacagttccc tttttatttg gaagataaag cttttttcag attcaattta ctaaaaacta
    82141 gcatgcttgt tactgcgatg aattgcgtta atggcacgcc tgcgccagtg tagacactta
    82201 aaaaataatc ctttttttct ggcgcataag aacaaaacca cgagacaccg aaaagaaaaa
    82261 ccaattgtgt cagtattaat ccgatgacta caatcaaaga ggaactataa taggcacgat
    82321 cagcttttgc aaatacggtt cctagtatca taagtaatat ccctgctatt gaagcaatca
    82381 gcacgggaat ggccagaact tggtaaattt ttatcatgac attcgcgact tttgctgttt
    82441 ttgtcaactg gaaatcaggt gttctcggat cactgctatc gatccaatta tccattagtg
    82501 gaagattcaa taattcttgt gcctgttcga cttgttcttg cgtcccaaaa ctataattcc
    82561 ccccttgatg gaaatctttg tatcgccatg cataagcata tcctgatttc agaaaatcaa
    82621 atacgattgg cagatcattc atcgtctttc catcccctga tcccatcaga tagaattctt
    82681 ttttcttttt gatagttccc ttttgatagg cttcttctaa ttcttgattg acttttttcc
    82741 aaaaatcatt ggtttctttt gcattgtttt ggtaataacc agattcgctt accacatctc
    82801 gcaatgccca aaaaatgata tctcctggta attcttttac ttttccgcct tgggtccacg
    82861 catgagtcgt atacaattcg tcaatacgag tagaaacagt atgaaatgta ggagatgcgt
    82921 ctaaagcttt atttaatgca gcatgcgaga cccatatctc actgttttct ttatttaagt
    82981 ttgtttcgtc atctattcgg atcagctgtt tcatcaaacg tccaaattcg ccactcgaac
    83041 ggtcattgat ggctgcaata ccatatgttg tctcgttttt atattcgatc cactgataga
    83101 cgatggagaa accgactaga gggagtaaaa acaatgaaag tttcagccat tcttgtttcg
    83161 aaaggagaaa tggtcgttct tttaacttct ttgcttcttt gaaagaaaag tcttgtccta
    83221 gcaagatctg aacgaaactg atgcctaacg cgactacagt aaaaggaaga agccagatgg
    83281 aatcttcgcg aatgaaccaa aagaaaggaa aagaaacagc tagccctaaa aaccacggca
    83341 gcaatttttt gctggaatta tatttgcggt aataaatagc tagtaaacaa gcgataatga
    83401 tctcaacagt cgggatcacg agagcattac gatatgttcg agtggaatat tcatgtgtaa
    83461 aactaatcgg agaaaacaaa aaataaaaat agatacttaa aagaagatac ttgttcttca
    83521 cgattggttt aaacgctagt gcaaccaata tactggcaag aatactgaac atgccgaata
    83581 aaactgcata agaaagatgc agtttatgtg caagtactaa aaacaagctg taggaaatcc
    83641 cttttgaaag tgtcgtagtc gtgtactccc ctagccattt accatccaaa atattttgag
    83701 catagtgaat cagcagctga tcatcatagg tcgccgacat atctgttcca tagattgctt
    83761 tactatataa atacaaccga ataattgtaa ataatacggc tatgccaaga ataaagtatg
    83821 tatgtttctt ttttagttgg tcgatcaagg ggtttaaaat gttcagcatc ttttcgtcct
    83881 ttcaatcacg ttttgctact tgtttgtgaa acttttcgtt ttttactttt ctatcagtat
    83941 accctgtttg tctgaattta aaaagagggg gcaaaaggag catggcgaaa acgaatgcaa
    84001 aaagcactcc tttgtttctt aaacaaaaaa ggacaaggca gactgcccaa tccttttttg
    84061 ttgctgtcag gtagaaaact taaagtgtga cttcttctgc taataactca gggaacactt
    84121 cgggatcgaa tgcttgcgct ttgaacatgg aaatttcttt tccatatggt gcgtaagctt
    84181 tctttttatc tttaccgaca tatggggttt ctaatatttt cgaaatgttg tcaaacattg
    84241 gatcatggac gattttgttc aatgtgtcaa atccaattgt tccaaaaccg atattggcat
    84301 gccgatcttt atgagaacct tgaggatttt tagaatcatt gatatgcagt actttaagcc
    84361 gatctaatcc gatgacctta tcaaactctt ccattacacc tgaaaaatct tcttttatat
    84421 tatatccggc atcattcgta tgacatgtat caaaagtaac ggataatttt tcattcaatt
    84481 ttactccatc gatgatttgc gctaattcct caaatgttcg accgatttcc gtacctttcc
    84541 ctgccatcgt ctccaaagcg atctgtgccg tctgttcttt tgtcaaaact tcattcaacc
    84601 cctcaataat tctagcaatc ccagcttctg cccctgctcc tacatgagcg cctgggtgaa
    84661 gggtgatttg agtagcacct aaagcttccg cacggacaat ctcttctctc agaaattgta
    84721 cagcaaatgg aaacatttct ggtttgatcg tatttcccaa attaatgata taaggcgcat
    84781 gaacgacgat atttgttagt ccgttttctg ccataaatgc ttttccggca tcaatattca
    84841 tctcttcgat agcttttctt ctagtatttt gaggagcgcc tgtatagatc ataaaggtcg
    84901 aagatccgta actggctgct tcttctgccg cgcctaacag cattttcttt ccgctcatgc
    84961 tgacgtgtga gcctaataac atggatggat tcctccttga aaggcaattg tttcgaacaa
    85021 ttcctgtata ttgataagat gatgtacaaa gaaaatagtt tgtttttctt tgccctgttc
    85081 tccatagtaa ctgaaacttt ccctaaagaa aagcttaaga actctttcat aaaaaagatc
    85141 atttcctcac gttttatctc attcgaaaaa gaaattcctg tcaaaaacag ccttgtctgt
    85201 ttttttgtcc tattatttgc tataattagc gaaataaaac cattagttga ggtgaccctt
    85261 ttgccacgca aaaatactcg aaaaaaacag aatagaagaa aaaaagaaaa atggtttgtt
    85321 cctaagatta tttttagagt gtttcaatca ttgactgttt ttattactgt tcttcttttg
    85381 ttgttcgcag ctctaggtat cggaataggt gctggctact ttgcctatct tgtcgaagac
    85441 acacaattgc cgactaaaaa agaactgcag acagaactag gaaacattac ggaaacgtca
    85501 aagattgttt atgcagataa tacagagata tcaaaaatcc agacagatct gatgcggacg
    85561 actatttcat ctgataagat ttcgccttta ttgaaaaccg cgattatcag tacagaagat
    85621 gaatacttcg ataaacacca aggttatgtc cctaaagctg ttttacgagc actagtttca
    85681 gaagcgactg gcatcggctc gtctggagga tccactttga cacagcaatt agtcaaacaa
    85741 cagatcctaa ccgatgaaac aacattcaaa cgtaaagcaa acgagatcgt tctttctgca
    85801 caagtagaaa aacacttttc aaaagatgag atcattacta cgtatttgaa tgtctcacca
    85861 tttggtcgga ataataaggg gcaaaatatt gctggagtcc aggaagctgc tagaggaatc
    85921 tttggtgtag atgcaaagga tgtgactctg ccgcaagctg cttatatcgc tggtttgcct
    85981 caaagcccta tcacgtatag tccatacacg aatacaggcg cgctaaaaga agatctttct
    86041 gccggtcttg ccagaaaaga ttttgtttta ttcagtatgt accgtgaagg acaaattacg
    86101 aaagaacaat acgaagaagc gaaagcctat gatcttacaa aagactttct cccacaacaa
    86161 atcgcggaac agactgacag agaattcttg tattataccg tgatgaacga agcaacaagg
    86221 attattgcac aacaattggc agaaaaagat aatgctgata tgtcagattc atcggtcagt
    86281 gaagcttatt atcaaaaagc acagcaaacg atccaaaaca aaggatatac gatccattcg
    86341 acgattgata aagatatcta tgctgcattg caaaccggcg tagaaaatta tggctacatg
    86401 ttagatgatg gtgctggtag ccaagtggag actggaaatg tattgatgga taacagaacc
    86461 ggacgtatct atggcttcgt gggtggtcgg aattacagcc agaatcaaaa taaccacgcc
    86521 tttgatacag aacgtcaagc tggttcatcc atcaaaccgg ttcttgttta cggtcctgca
    86581 atcgatatgg gacttgtcgg atcagaatcc cgtgtatcag attatgcaac gacttggcaa
    86641 gaaggaaaaa atgctggtga gaaaatcgtc aatgcgacca atgaagggtc gaacaccttc
    86701 caaaccgtcc gtgagtcact ggaatggtcc aacaatatcc cagcttatca cttatatcaa
    86761 gatgtgttga attccggtgg atcgaaacaa tacgcttacg agcactactt ggcgaagatg
    86821 aactacccag caaatgataa ttggggcgtt gaatcggctc ctttagggac agtagatgta
    86881 acgacgcttc aacagacaaa tggattccag gccttagcaa atggtggagt ctacgaagaa
    86941 ggctatatca ttgattccat cacagataat gcaggtaatg tgatttataa acatgaaagt
    87001 aattctgtcc gtatttattc cgaagcaacg gcatcgatca tgaatgacat gatgcgtagt
    87061 gtgatcaatg aaaaaatcac tacaccattc aaagatgtca tctcaagctt aaacggaaat
    87121 ctaggaaatg cagattgggt cggaaaaact ggttctacca atgaataccg agattcatgg
    87181 ctgatcgtct caactccatc tatcactatc agtagttggg caggacacga tgacaatact
    87241 ggaatggaca gccaagcaag aatacgttcg gctaattatc ttgccaatct aatcaatcaa
    87301 gcttaccaag caaaccctga gattttcggc actgatgaga aatttgactt atcatccgat
    87361 gtgatgaaga aaaaagtatc tgggttcaca ggacaaacag ctggaaaagt tactgtcaat
    87421 aaaaaatcta tccaaacgcc aggaaaaaca gtggaatcac tttgggcaaa aaatggtccg
    87481 aagaaaagcg cctttaaatt cggcgttggc ggtactgatg aaaactatac agattactgg
    87541 aacaccgctt cagcttatgc tagagcgaat ccagagacca aagaatcaga cgataaagat
    87601 gattgatcta atagattaat cagaattaaa gggagctgcg acaaaaatct tgtcacagct
    87661 ccctttttcc gaataaatgg tgttcaaaag cttacatcta cgatattaag acaaatttat
    87721 gtaaaaatgt gaaaaaccat tttcacaaaa tttttctata taactttact aacgaaactg
    87781 ttttaatttc ttttcttgtc tttggaataa ttcggttagt ttttctgcaa attgcccttt
    87841 tactgattct tttaagtgtg catgtcggtt agaaaattct tgagtagctt cttctgcagt
    87901 catttggtgg ttttgatctg tcaatcgttt ttctgcccaa gtttgctgag atatccccat
    87961 accaactgaa cgtacatttg atcgatgtag atttttctct aattctttta gtaattgcat
    88021 taaaaattca ttcataagat gatttctcca tagttatttg tctgattttt tgacgatagg
    88081 aacgttctag ttcgtcttgc tgctgataga gttttcgtcg ttctacttgt agggcttgtt
    88141 gataatgctc ctgataattc gaataacttc gtcttgcttg aaacagaggc tcattatcta
    88201 aagctaagtt ctttaataca tgatgcagtc gctgctcctc ttgctccatc aatcgtaatc
    88261 cttgattctt aaagtggatc aattcatctt cttgagcttc taattgtctt cgttcacttc
    88321 gataatctct ttccaattct tctagtttca tctacttctc ctttaattga attgctgtgc
    88381 taattctcga tctcgtgcca cgatttcatt gattttgtct tggatctcct tcgccaatgt
    88441 atcaaaggcc tcccccatac gtcttgcctt attgattcgt agcagataga cttctttcgc
    88501 agaatcgact aagttctctt ttgtggcgcc cacactagct aatgcttcta tgatttcctg
    88561 ttcagtcaac gaaggggcga caacacgtgc ttgccgcaag ccttcttgcc attttttctc
    88621 tagctcaaaa attcctcttt ggttgatgcg gataacttct tccatagcgc ttttcatttt
    88681 taccgataac ttttccacca ctaacctagc ttgtgtgtca tctaagtaaa tttgttcatt
    88741 aactgtcagc cggccgccac ttaatcgtag ttttttacgt atgttgttca gttcttgcaa
    88801 ctgataggaa aacaactggg tcgcttggtt ttctttctgt tgttttcgag ctttaacatt
    88861 gttttcattt tcaggaataa tcagctttcc attttcatca aacttccaag aggttaaact
    88921 gtgggaagca agcagattca agtatgctgt ttccatactg atccgaactt cagcacctgt
    88981 gccattacca ccaaaattac cgataaaatc ggcgtgattt cggtaattgg tgagcatacc
    89041 gggattttct tccacccatt tttttgcttc tggtgataag agatcatacg ggtccggccc
    89101 gttgaagccg acatttttcc attgtttctc tgctgctaca tataatgcta agaatccacc
    89161 taatgaatgg ccggtagtag aaatagcagc ttctccatat tcctttttta cttcattagc
    89221 aaatgcaatc gctgaattga tttgccccgc tgttttcaat ccactaacgg ataaaatctt
    89281 gtttgttgtt gctttttcag aaaaacttgc tcctggtcta ttcccataga gattcataac
    89341 acttcttgca tccgtttcca aatctttcca atcgcttaag ttcgttcctg caaaagcaat
    89401 cactacttga gaaatatcca ctttaccgtt cttgattggc gctacagcca tcgcctgcat
    89461 gccgtcgaag gagtttttga tttttaggat ttggaatttt gtttctccaa agtttttaat
    89521 ggcgccttct ttgtaacttt tactatattg aggatgtttt ggatctagcc aatatacttt
    89581 attacttatt cctttatact gcttatcagt aattgtcata ctttttcctc actcccatct
    89641 gtatagataa ctataatctc atcaaccgta atcccttctt tttgtacttc ttcattttca
    89701 acaccatagc catctatctc attgctttct tttgtaaagc tataatcaaa ataaacggct
    89761 tttccttctg tattggtcat cgttatcaat gcttcataga ttcctgtcat gtcgtttttc
    89821 tcaaattgtt cgattttcac ttctttgata tccgcaaagg tatttttcag aactttgacg
    89881 gactgttttt ctactgcgag taaatcttgc tgtttttgcg cttctctttt gtccatgtaa
    89941 aattttcctc cgattcctat agtaagaatg gtcaaaatga tgactatggt ctttcgtctt
    90001 ttcttaggca aatagaagtc tcctttcggg ttatgtatga tggattgttt ctcctttaag
    90061 ataagtacgc aatcgagcct ggattttttt ggatttttta gagttacttt tctacttttc
    90121 tactttcttt tttatcacgt tttcatttta aagtaatttt gatagtagtg aacaaaatgt
    90181 agcatctacg cacagattgt gtcgtatacg atggacgtaa ggtttgtttc cgccattctc
    90241 tctttttttt aaagtcacaa aaaaaggggt tatgacaaaa ttttgtcata accccttttc
    90301 tcgtataaag gttgttccag aagttgacca ctttgggaac aacctttaaa tgattgatct
    90361 tttattattt agttgatcct ttttcttcga ttccataagg caagataatc gttttttctt
    90421 cgacttcttc tttattcatc attttcgtca ataggcgcat ggataccgct cctaaatcgt
    90481 ataatggttg tgtgatactt gtcaaacgag gacgagctac ttctgtcagt aaagaattgt
    90541 tgcttgtgat gatttcgaat tcttctggta cttttacgcc gcggtctaat aaaccatcca
    90601 agataccaat ggctaattca tcgtctgaaa catagacagc tgttgcaccg ctattatgga
    90661 tccggtcaac tagagacaga ccatctttaa agttgtattg tgcctcaaaa atcaatcctt
    90721 cgctatatgg tagattgttt tcgcttaatg cttctttata gccttttaga cggttttgac
    90781 cattgatagg atcaatcagc gcaccgctga caaaagcgat ttttttattg ccgctttttg
    90841 ctaatttatt tactgcatct tttgttgctg atacataatc aatgtttacg ctacctactt
    90901 gttcatctgg atcaatggaa ccagctagta caacaggcgt ttttgaacgt gaaaattctc
    90961 cacggatttc gtctgtgata tggtgaccca taaagatcac gccgtccact tgcttagcca
    91021 ataaattatt caatacattg acttcttttt gatcgttgcc atctgagttt gctaagatga
    91081 tattgtattt gtacattgtt gccacatcgt cgataccacg tgctaaagag gcaaagaaca
    91141 tattgctgac atcaggaatg attaccccaa ctgttgttgt tttcttactt gccaagccac
    91201 gtgcgactgc atttggacga taatccaagc gatcgataac ttccaagact ttttttcttg
    91261 ttgctggttt gacgtttgga ttgccattta cgacacgtga aacagtagcc atcgaaacat
    91321 ttgcctctct cgctacatca tagatagtga ttgtttgctt ttccatttgt gttctcctat
    91381 tcatatttta tatgttttct gaaaatacgt cttacatttc taaaatagga tatcaaataa
    91441 tctcaacaat tgcaaccgtt ttatctctgt tttcatgaaa atttttactt ttttcagttt
    91501 taagaacgtt ggtcttttaa tcaatcagtg gtacaattat tgaatacaaa attaatttag
    91561 aaagtaggtt gccaaatgaa taacgtaaaa atcaatgaac tacgtcaatg gatggcacaa
    91621 caccaattag aattggctta tatcagcgac cctggccaca tcgcttactt ttccggatat
    91681 gaaagtgatc ctcacgagcg tgtactagct ctttttatcc ctctggaaca agatcctttc
    91741 cttttcactc ctgctctgga agttgaagat gctcaaaaca gcagctgggc gtacgatgta
    91801 cgtggctact tagacagcga aaatccttgg gagatcatcg gaaaagagct tcgcgcacgc
    91861 tatgggcaac ctggtaatgt aggtattgaa aagaatgctc tgactgtcga tcgcttcgat
    91921 gctatctctg atatcttgac aggtacagat tcttacaccg atctaacttc tattatccag
    91981 cgtctgcaac tgatcaaaac ggtagaagaa aaagacaaac tgatcgaagc tggtaaatgg
    92041 gccgatgttg cctttgaaat tggcttcaaa acagtaaaag aaggcgtaac tgaacaagca
    92101 attatcgcag aaatcgaata ccaattaaaa aaacaaggtg tttcacaaat gtctttcgac
    92161 acattagtcc ttgcaggagc aaatgctgca agccctcatg gtacaccagg aagcacgaag
    92221 gtttcaccaa atgaactagt gttattcgat cttggcgtta tttggaatgg ctattgcagt
    92281 gatgctactc gtacagttgc ttatcaaaaa ccaactgaat tccaagaaaa aatctataac
    92341 atcactcttg aagcacagct tgccgcacaa gaggcagttc gcccaggtgt gacagcaggt
    92401 gaacttgatc aaatcgcacg aaacgtgatc aacagctatg gctacggcga atatttcaat
    92461 caccgtttag gtcacggaat cggaacaacc gtccacgaat tcccttctct tgtagaagga
    92521 aacgacttag tgattgaaga agggatgtgc ttctctcttg aaccaggaat ctatattcct
    92581 gaaaaagtag gggtacgtat cgaagattgt gtgtatgtga caagtgatgg ttgtgtgcca
    92641 ttcacgacta caccaaaaga attacttgtt ttagagtaat gaaaataaaa aaggtgagag
    92701 ctggtccgct ctcacctttt ttattctaga aatgagtaat cttagtgatt ggtagtcgaa
    92761 tctgtcattg tatctttcat ttctttttta gcttcttttg catcttcttt tgcatcttct
    92821 tttgccattt tcaacatttc ttttgtgtca tctgcaactg gttttgcttc tgacattcct
    92881 tcattgaccg tctctcctgc tttatctgca gcatctttta catcgatcat gatatcttct
    92941 gaagtatctt tagcaatact acctaattcg tctgctggct ttttcagatc ttctgctgtt
    93001 tttttgaaac gattagataa atcagctgat tgttctttga ggtttaacaa gatatcatct
    93061 gattcgcttc ctgcttcctc tgctgattca cttaccttct gcttaacatt gcctgctaga
    93121 tcccctgctt gttgagaaag atcttgcgct ttttcttttg caatacctgt taactcagat
    93181 gatttttctt ttgccatatc tgtgtaatct gaagccatgt ccatcaaatc atctgcttga
    93241 gcagccaatt catcccgaag ttctttacca gatttgggtg ctaacaataa tgcggcgatt
    93301 gctgcggctg tacctccaac tactgcacct aataaaaatc cacctttttt agccattctt
    93361 attttcctcc tgtcgtttca gtatgttttt tgtttttaaa aatttcatcg ctgttccacc
    93421 gacttttccg gcaacagtcg ctttagctgt cgtttttccg attccgccga ctttcgtcac
    93481 gatgttttta ctagaatgat taagttccga tacactttca cttaaatcag caactgctgt
    93541 gaacaatgga tcgatcgttg cgacttttcc attgatatcc aagagcagct cattactttt
    93601 gactagcaag ccttctactt gtctagataa aagatctacg tcttgtgtga cgatctcaat
    93661 tgtcgtattt gcttctgcga cagtctggtc tactttttct aaagttttgg aaacttgcaa
    93721 caatacgcga acgatgaaaa cgacaagtat cgcaaaggcg attgctgcga tcaatcctgc
    93781 aatttctcct cctgacatga tcaaactccc ttcttgtctc tcttttctat aaggatagca
    93841 ttttcgtgtt ttttaaacaa ataaaaacga gcttcaacta ctttttattc aattagcagc
    93901 tgaagctcgt tagaaaaaaa gattattttt tcttttcttc tttgatttct gttattcctt
    93961 ttggattatg attgatcttg cttccttctg cttctaatgt tttacctaaa gacatgatgt
    94021 attcacgcaa aggtgcccct acttctggat gtgtcagacc atattcaata cttgttttca
    94081 taaaaccaaa tttgtcacca acgtcataac gtttacctgt gaatttacgg gcaaatacgc
    94141 gttgtgtttt attcaacgta tcgattgcgt cagttagttg gatctcattt ccagcgcctg
    94201 gttgttgttc tgataataca tcaaagattt ctggagtcaa taagtaacgc ccaataatag
    94261 ctaaatcact tggtgctttg cttggatctg gtttttcaac aaagtttttg acattgtata
    94321 acccatcttc cagtacttcc cctgggttga tgattccgta ttttgaagtt tcatcgtgag
    94381 gaacttgcat aacggcaatc gtagaagcgt gtgtacgctc atagtcatcg atcaattgct
    94441 gtgtcaatgg tacttcgtct tccatgatat catcgcctag cataacgaca aacggttcat
    94501 ttccaataaa ggctcttgct tgaagaacgg cgtgtcctaa cccctttgga tgagattgac
    94561 ggatgaaatg caaattgaca tctgtcgttt cttctactaa tttcaataat tcggtttttc
    94621 ctttttcact taggtttgtt tctaattcga tatttgaatc aaagtgatct tcgattggtc
    94681 gtttagcttt tcctgtaacg atcaagatgt cttcgattcc tgatttcaac gcttcttcaa
    94741 cgatgaattg gatcgttggt ttgtccacga ttggcaacat ttcctttgcc atcgcctttg
    94801 ttgctggtaa aaatcttgtt cctaatcctg ctgctggaat aactgctttt tttactttca
    94861 tatacattcg ctccttcaaa aaattgttaa tgagaattca ttttcttttt tcccatcacg
    94921 taacatgatt tcttttgcgg ctgttttgat ttctttttgt tcatacagca cttcatagat
    94981 tgtttgagtg atgggcattt cgatttccat catttgggct agttccatcg ctgcttgagt
    95041 agtattcaca ccttcaacaa ccattcccat attggctagc acctcttcta gaggctgacc
    95101 ttgtcctaac aagttgcctg cgcgccagtt tctggaatga acacttgtgc aagtaacgac
    95161 tagatcacct actccgctta agccaataaa ggtcagcggg ttggcaccca ttgctacacc
    95221 taaacggctg atctcagcta atccgcgcgt catgattgcc gcttttgcat tatcgccaaa
    95281 ccctaagccg tgaatagcac cagctccaat ggcaataata tttttcaaag ctgctcccat
    95341 ctctacacca atcacatcag ggttggtata gattcgaaaa taatggttca tgaacagctc
    95401 ttgtacatat tttgctgctt ttacatttgt gcttgccgct gtgatcgtcg taatgtcatg
    95461 ctttgctact tcttccgcat ggcttggccc agaaagaaca gcaacagctt ttcttttttc
    95521 tgtcgggatt tcctctaaca agatttcaga gattctttta tgcgttccct gttctaatcc
    95581 cttacttgcg tggatgatca ctggcttcgt attcaatttg gcaactagtt cttttgcaac
    95641 agaacgtatc gctttcgtcg ggataacgaa tagtaccgca tctgcatctt ttactgcatc
    95701 ttccatatcg gtgaatgctc ggatggaatc gggtagatga tgatctggta aataacgttg
    95761 attggtgtgt tgggtgttga tttcttctac ttgtgaagca cgatgtcccc aaatccgaac
    95821 gtcatgtccg ttttcagcga ggacttgtgc taaagcagtc ccccaagagc ctggtcctaa
    95881 aaccgctact ctataattca ttttaccact cctgaaattt ttttcatttt taacgctctg
    95941 aaaatcaaat aatttgttga ttttttccta atgagcggtc ataatccggt aaacttcctt
    96001 tttttctacg ccaaataaac agaatcaatg tgccgacaaa taaaacagca gacaataatt
    96061 gagaaatgcg gatcacacct aaaaagtaaa ggctgtctgt gcgtaaccct tcgataaaga
    96121 aacgtccgaa actataccac attagataac ataaaaggac ttctcctttt ttcaaaagat
    96181 gtggtttctt ccgcaaaacc aaaagcagaa taaatccaat caaactccaa agtgattcat
    96241 aaagaaaggt tggttgtcga tagattcctt cgatatacat gttatcaatg atgaattgcg
    96301 gtaaatgcag actttctaag aaacttcgtg tcgtgtctgg accatacgct tcgtggttca
    96361 tgaaatttcc ccatcgtccg attgcctgcg ccaataatac gcttggtgca gcgatatcta
    96421 aaaaggtcca caaagaaata aaatgatatt tggtaaaaaa gtacagtgtg attgcacctg
    96481 caatcaatcc cccgtaaatc gctaatcctc ctgaacggat attgaatatc tggattggat
    96541 cagctatata ttggggaaga tcgaataaaa cataatacaa gcgggcacca ataatggaaa
    96601 tcggcaatcc ccacaacata aaatctgtca cgtcatctgc ttttaatcct acccgaacag
    96661 cttctctgct gctgagccac atggcaataa tgattcctga tacgataatc aatgcatacc
    96721 agtagatagg aattcctaca agctcaaaag caactcgatt gatttgtgct aacatattgt
    96781 cactccttgc tagtcattgc ctgagttttc ttcaatcaag cgacttaatc tttcttcaaa
    96841 tgttttcgtt gcgtcaaagc ccattgtacg tgcgcggaaa ttcattgcgg ctacttcaat
    96901 gatgattgca acgtttcgtc ctgttttgac agggattttt atttgtggaa tgcccacttc
    96961 cgcgatttca acggtcgtgt cttcagagcc cagacggtcg tatttcttat ctttcgccca
    97021 tgcttctaga taaacagcta actggacttg catagagcct cgtaccgcac tcgcaccgaa
    97081 aagattcatt acatctatga taccgatccc tcgaatctca atcagatgtt ccaggatttt
    97141 aggaggttct ccgattaccg tcagttcatc ttgctgatag acatctactc gatcgtctgc
    97201 gatcaatcga tgtccgcgct taatcagttc caacgccgtt tcacttttcc ctatcccact
    97261 gtccccttga attagtacac ctaatccgta gacatcgact aacacaccgt ggacacttgt
    97321 tcgaggggct aagcgtccat ctaaataact agataattca cctagcagcc gggacgttga
    97381 gataggcgaa cgcagcacag ctatcccatt ttcattggct gcttggatca tttcttccgg
    97441 agccggcaat cctcttgaaa taataaatgc gggcatatct tcactacata atcttctcat
    97501 aatgatcaaa cgctcttctg ggatcatccg ttccgcaaaa ctgatttctt tactgccaaa
    97561 tagctgtaaa cgattatggg aataataatt aaaataaccg gtcaactcta gtcctgggcg
    97621 tgagatgtcc ccagtcacga tgacgcggtc taaacttttc tcgtcgcctg tgacgatttc
    97681 caaagataat ttttttacta attggctaac ttttacaact tctgacattc atgctacctc
    97741 atttctatta gagtgttctc tatcatttta tcattgtcta gccaaaagta ctaccaatta
    97801 aaaaaaacgt ttttatttaa ttaccaatgt aatagaaaac gcattcttta ttctaaacaa
    97861 aaa
//
LOCUS       DAIGUC010000002        74204 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.002, whole genome shotgun sequence.
ACCESSION   DAIGUC010000002 DAIGUC010000000
VERSION     DAIGUC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.002"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(606..962)
                     /locus_tag="NOB46_000090"
     CDS             complement(606..962)
                     /locus_tag="NOB46_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HCI1057079.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /gene="spx"
                     /locus_tag="NOB46_000091"
     CDS             complement(976..1386)
                     /gene="spx"
                     /locus_tag="NOB46_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI1057080.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            complement(1732..3918)
                     /locus_tag="NOB46_000092"
     CDS             complement(1732..3918)
                     /locus_tag="NOB46_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI1057081.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            4136..4819
                     /locus_tag="NOB46_000093"
     CDS             4136..4819
                     /locus_tag="NOB46_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCI1057082.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(4900..5619)
                     /locus_tag="NOB46_000094"
     CDS             complement(4900..5619)
                     /locus_tag="NOB46_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI1057083.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(5931..6137)
                     /locus_tag="NOB46_000095"
     CDS             complement(5931..6137)
                     /locus_tag="NOB46_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057084.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            6382..6984
                     /locus_tag="NOB46_000096"
     CDS             6382..6984
                     /locus_tag="NOB46_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI1057085.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            7125..8405
                     /locus_tag="NOB46_000097"
     CDS             7125..8405
                     /locus_tag="NOB46_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI1057086.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            8418..9146
                     /locus_tag="NOB46_000098"
     CDS             8418..9146
                     /locus_tag="NOB46_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1057087.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(9215..10738)
                     /locus_tag="NOB46_000099"
     CDS             complement(9215..10738)
                     /locus_tag="NOB46_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI1057088.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            10990..12171
                     /locus_tag="NOB46_000100"
     CDS             10990..12171
                     /locus_tag="NOB46_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1057089.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(12231..13859)
                     /gene="treC"
                     /locus_tag="NOB46_000101"
     CDS             complement(12231..13859)
                     /gene="treC"
                     /locus_tag="NOB46_000101"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCI1057090.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(14310..17021)
                     /locus_tag="NOB46_000102"
     CDS             complement(14310..17021)
                     /locus_tag="NOB46_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057091.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(17031..17732)
                     /locus_tag="NOB46_000103"
     CDS             complement(17031..17732)
                     /locus_tag="NOB46_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057092.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            17918..18517
                     /locus_tag="NOB46_000104"
     CDS             17918..18517
                     /locus_tag="NOB46_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1057093.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            18598..19611
                     /locus_tag="NOB46_000105"
     CDS             18598..19611
                     /locus_tag="NOB46_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI1057094.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            19719..20636
                     /gene="rbsK"
                     /locus_tag="NOB46_000106"
     CDS             19719..20636
                     /gene="rbsK"
                     /locus_tag="NOB46_000106"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCI1057095.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDALDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            20664..21059
                     /gene="rbsD"
                     /locus_tag="NOB46_000107"
     CDS             20664..21059
                     /gene="rbsD"
                     /locus_tag="NOB46_000107"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCI1057096.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            21059..22432
                     /locus_tag="NOB46_000108"
     CDS             21059..22432
                     /locus_tag="NOB46_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1057097.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            22789..24933
                     /locus_tag="NOB46_000109"
     CDS             22789..24933
                     /locus_tag="NOB46_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI1057098.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(24985..26025)
                     /locus_tag="NOB46_000110"
     CDS             complement(24985..26025)
                     /locus_tag="NOB46_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI1057099.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26302..28104)
                     /locus_tag="NOB46_000111"
     CDS             complement(26302..28104)
                     /locus_tag="NOB46_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057100.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(28118..28870)
                     /locus_tag="NOB46_000112"
     CDS             complement(28118..28870)
                     /locus_tag="NOB46_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057101.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(28879..29241)
                     /locus_tag="NOB46_000113"
     CDS             complement(28879..29241)
                     /locus_tag="NOB46_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1057102.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(29417..30289)
                     /locus_tag="NOB46_000114"
     CDS             complement(29417..30289)
                     /locus_tag="NOB46_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI1057103.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(30340..30828)
                     /locus_tag="NOB46_000115"
     CDS             complement(30340..30828)
                     /locus_tag="NOB46_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HCI1057104.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(30966..31757)
                     /locus_tag="NOB46_000116"
     CDS             complement(30966..31757)
                     /locus_tag="NOB46_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCI1057105.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(31812..32420)
                     /locus_tag="NOB46_000117"
     CDS             complement(31812..32420)
                     /locus_tag="NOB46_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCI1057106.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(32413..32730)
                     /locus_tag="NOB46_000118"
     CDS             complement(32413..32730)
                     /locus_tag="NOB46_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1057107.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(32886..33614)
                     /locus_tag="NOB46_000119"
     CDS             complement(32886..33614)
                     /locus_tag="NOB46_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCI1057108.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            33773..34654
                     /locus_tag="NOB46_000120"
     CDS             33773..34654
                     /locus_tag="NOB46_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1057109.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(34891..35934)
                     /locus_tag="NOB46_000121"
     CDS             complement(34891..35934)
                     /locus_tag="NOB46_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1057110.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(35937..36605)
                     /locus_tag="NOB46_000122"
     CDS             complement(35937..36605)
                     /locus_tag="NOB46_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1057111.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            36747..39083
                     /locus_tag="NOB46_000123"
     CDS             36747..39083
                     /locus_tag="NOB46_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1057112.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(39198..39509)
                     /locus_tag="NOB46_000124"
     CDS             complement(39198..39509)
                     /locus_tag="NOB46_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057113.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            39690..41165
                     /locus_tag="NOB46_000125"
     CDS             39690..41165
                     /locus_tag="NOB46_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCI1057114.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            41212..41796
                     /locus_tag="NOB46_000126"
     CDS             41212..41796
                     /locus_tag="NOB46_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCI1057115.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            41798..42217
                     /locus_tag="NOB46_000127"
     CDS             41798..42217
                     /locus_tag="NOB46_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HCI1057116.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(42498..42782)
                     /locus_tag="NOB46_000128"
     CDS             complement(42498..42782)
                     /locus_tag="NOB46_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HCI1057117.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(43134..43844)
                     /locus_tag="NOB46_000129"
     CDS             complement(43134..43844)
                     /locus_tag="NOB46_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HCI1057118.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(43841..45313)
                     /locus_tag="NOB46_000130"
     CDS             complement(43841..45313)
                     /locus_tag="NOB46_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI1057119.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            45451..45924
                     /locus_tag="NOB46_000131"
     CDS             45451..45924
                     /locus_tag="NOB46_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1057120.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(46077..46628)
                     /locus_tag="NOB46_000132"
     CDS             complement(46077..46628)
                     /locus_tag="NOB46_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1057121.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            46733..47263
                     /locus_tag="NOB46_000133"
     CDS             46733..47263
                     /locus_tag="NOB46_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HCI1057122.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(47746..48189)
                     /locus_tag="NOB46_000134"
     CDS             complement(47746..48189)
                     /locus_tag="NOB46_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1057123.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(48205..49365)
                     /locus_tag="NOB46_000135"
     CDS             complement(48205..49365)
                     /locus_tag="NOB46_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1057124.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            49872..51572
                     /locus_tag="NOB46_000136"
     CDS             49872..51572
                     /locus_tag="NOB46_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057125.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(51674..52507)
                     /locus_tag="NOB46_000137"
     CDS             complement(51674..52507)
                     /locus_tag="NOB46_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCI1057126.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(52811..54976)
                     /locus_tag="NOB46_000138"
     CDS             complement(52811..54976)
                     /locus_tag="NOB46_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1057127.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            55236..57530
                     /locus_tag="NOB46_000139"
     CDS             55236..57530
                     /locus_tag="NOB46_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI1057128.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTTHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            57523..58188
                     /gene="pgmB"
                     /locus_tag="NOB46_000140"
     CDS             57523..58188
                     /gene="pgmB"
                     /locus_tag="NOB46_000140"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI1057129.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            58181..59188
                     /locus_tag="NOB46_000141"
     CDS             58181..59188
                     /locus_tag="NOB46_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI1057130.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            59210..60229
                     /locus_tag="NOB46_000142"
     CDS             59210..60229
                     /locus_tag="NOB46_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1057131.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(60510..61877)
                     /gene="nhaC"
                     /locus_tag="NOB46_000143"
     CDS             complement(60510..61877)
                     /gene="nhaC"
                     /locus_tag="NOB46_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI1057132.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(61986..63407)
                     /locus_tag="NOB46_000144"
     CDS             complement(61986..63407)
                     /locus_tag="NOB46_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1057133.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(63650..65527)
                     /gene="tdc"
                     /locus_tag="NOB46_000145"
     CDS             complement(63650..65527)
                     /gene="tdc"
                     /locus_tag="NOB46_000145"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI1057134.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(65818..67074)
                     /locus_tag="NOB46_000146"
     CDS             complement(65818..67074)
                     /locus_tag="NOB46_000146"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCI1057135.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(67186..67391)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            67654..68955
                     /locus_tag="NOB46_000147"
     CDS             67654..68955
                     /locus_tag="NOB46_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI1057136.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(69024..69623)
                     /locus_tag="NOB46_000148"
     CDS             complement(69024..69623)
                     /locus_tag="NOB46_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1057137.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            69877..70758
                     /locus_tag="NOB46_000149"
     CDS             69877..70758
                     /locus_tag="NOB46_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057138.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            70771..72381
                     /locus_tag="NOB46_000150"
     CDS             70771..72381
                     /locus_tag="NOB46_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI1057139.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(72458..73117)
                     /locus_tag="NOB46_000151"
     CDS             complement(72458..73117)
                     /locus_tag="NOB46_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI1057140.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(73400..74065)
                     /locus_tag="NOB46_000152"
     CDS             complement(73400..74065)
                     /locus_tag="NOB46_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HCI1057141.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT        22144 a        14963 c        13229 g        23868 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1621 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1681 attccttctt ctttcttgaa actgaccact tctgtcacac cctctcttct atcactttcc
     1741 ttttttcaca cgactcccgg tttctttgat aaatctcgat actttcaatt ttcttgaatt
     1801 tttcatttga ggtacacata gatacagacg atttcttgct ctagtcatcg caacataaaa
     1861 tagtcttcgt tcttcttcta tcgtcgttac tggttctgct tttatttcat taaagtcgat
     1921 tactttcttt tctgtcgctc cgttataagg caaacttcct tcgttacaac caatcaaaaa
     1981 gacatttcgg taactaagac ctttactttt gtgaatgctc tggatacata gtgcatcaag
     2041 ttttccttgt ctgtaagcaa tcaagcgggt ttttaattct ttagctgtcg cttgggtttc
     2101 ttgcgataag gcttggagtc ttctgaaagt agcatgctgc tttacttctt ctcgtatcca
     2161 ttcttgatca ctctggtcga tttccttagc tatacgtggc agatgaagat agctttgaac
     2221 aagcgaatag atttcttgat gctggtctgt tttacgcaac gcttcctcaa actctcggat
     2281 ttctgcagat ttcgatttta aattggggct tatcgacaaa atataatctg caacggctat
     2341 attttgatat ttaggagaaa agtattgatc gcattcactt tttttcaggt agcagtctgc
     2401 catcagctgc cggagcaatt gctggtaggc ctgatttttc ttttgcagat tcagtgctgt
     2461 ttgccaatga acaatttttt gatagaaatg ttggaaagac ttgataccaa agataccttc
     2521 atatggacta tctgcttcca gtacaaaagg aatattcgtt ttcagcagag attggacaag
     2581 ctgctgcgtt tgtgaagctg atcggtataa tatgattgat tccttatatt tcccattttt
     2641 ttgaataaat gtctgaattt gtttgattag ccactgactt tctgctttag tatcagaaaa
     2701 caaataggct tccataacac ctgcttcttt ttgtgctgga atcatcgcct ttggtatccg
     2761 atcattttta ttatagctga tcaatctatt tgctccttgg acaatagctg cccgagaacg
     2821 ataattagtt aataagaaaa gagttttggt aggatattct ttttcaaagt tcttgatgta
     2881 tgctggctct gatcctctga atccatagat actctgatca tcatctccaa caacaatcaa
     2941 cttgatcctg ttttcctttg tcatccgttt cacgatttcc cattgaagtg gattagtatc
     3001 ttgaaattca tcaatgaata gataatcata tttttggccg atataatgct ggatctcctc
     3061 attctccaaa gcgcttttca gattttggag tacatcattg aactctagca attgctggct
     3121 tcttttttgt tcttggagtt ccgtgagcaa tccatacagt cgttctgata tcggctgtcg
     3181 tgcattctta tcaatggaat catatttttc tttaactaac tgaaccattt cttctactga
     3241 aaggttcata ttctgccaat agtctaaccg agaagcaatc gttttttctc catattgatc
     3301 aaatatataa agattatatt tacgtatcag ctgttgcaaa acagcattca ctttttgtgc
     3361 agtatccttt gaaaagtctc cttgtattcc ttgcattgct acttcaggaa attttcgaca
     3421 aatttcattg tatatcctaa aaaagatact atggaatgtt ccgatatgga cagcggtttt
     3481 tctctggctg aaattatcta ctcgtttttt tagttcattt gcagcgttcc ttgtaaaagt
     3541 gatcattagt atgcgttctt cgtctacttg tttttgcgtc atcagataaa cagcttttgc
     3601 acagattgtt tgcgttttgc cgctcccagc tcctgctatg attcgaagat gtttcttcat
     3661 atcatatgtg atagctgctt tttgttcttg attgaagcga ttataggaac gtttctccat
     3721 cattttaaag aaagagctgt ttccttcact ttcttttact tgtacttctt cctcaataag
     3781 tccgggtgct tcgccataag ccgcttcata ggtagcaatg atttcttctt gtagccgaaa
     3841 gacttgttga agctttttat acttgttctc ccagcgtttc aattcttttt gtaatcggag
     3901 aatttctttt tcattcaact gattgatttc cttcccatct ttcttctttg aatttgttta
     3961 tttcaagttg gttatttaaa gtttcgttgt ctattttttc tttatactaa cagacctttc
     4021 taaaaatgaa aatgggaagc gatatgattt tagttttctg aaaatttttc ctttttttca
     4081 atcgtttatg ctaagataag gaagacaaaa atattcataa aaggtgatga aaaaaatgca
     4141 gacttccttt cacgaggggc gtacaatagg acttttgctg acatttatcg gaggagccat
     4201 ggacagttat acttatatcc aatatggtgc ttttgcctct gctcaaactg gcaatatcat
     4261 tctatcgatc atccaagcat ttgacggaga atggctaagt gttggtaaaa aagtattgtc
     4321 tacccttttc tttttcttag ggattcttct aacaaagtat ctaattgatt attttagaaa
     4381 aaaagaaaaa catttctggc gcttgtttgt tctatattat gaagcagtga tttttttctt
     4441 tgttagtttg acacccgtcc atgagcatcc cgcattagta acgattttga ttgcttttac
     4501 tgcatcgatc cagtgggtag cttttgataa aatcaacggg cgtgcctaca ctaatttatt
     4561 tacaactgga aatttaaaag gggtagcaac gaacttatat gattattgta tttctaaaga
     4621 aaaagcagat tttgatcgat ttttccacta tctaagtgtc gttcttgcct ttatcgcagg
     4681 agctattgtc cttgttttct gtcatcatct gtttggcgcc cattcgattt tgatcgtttc
     4741 cattttattt ttgatcatgg ccctcactca gacatttcat ttatggcaat tttatcatac
     4801 gaatcggttc actatttgat ctcaatgaat caaaaaaact aagcaagatg ctgctcacag
     4861 agaaatatct gcgagtgagc aatttgctta gtttttatat tatttagttg taaagattcc
     4921 ctttgctttc gggttatttg tagtgtagcg gatcgactgg gcatctgcct cttctgtcat
     4981 tttctttgcc cgcatcttga tttcttgtac gatttgttct ccacatgccg gatcggctac
     5041 gaaatcatat ttgtccccat cgatcactat tttgggacat atatcaaact gttcatacca
     5101 ctcttcgtat cgtcgattga gttctttata gtaggaatag agttcaggat cttgttctag
     5161 ctgttcatat tcccggcctc tttttttgat tctcgctaac atagtttcaa aggatacacg
     5221 aatataaacc agtagatctg gtttcttttg tggcgaaatt tcttctaact ccttcagcat
     5281 cgtttctaaa agaccttcat actgctttac ttctacttca gaaacacgcc ctaaatctgc
     5341 attcaaatga aacagcatac tatcttcgta gatggagcgg tctagtacgt tgtcatcatg
     5401 gctgaaagca tctttgattg ccaaaaagcg tttgttcaaa aagaaaatct gtaataaaaa
     5461 agtatacttt tctggattag aataaaatag cggcaatact tcattatctt ccacgttctc
     5521 ataaaaaggt tttgtttcta aatcttgggc aagcatttca gttagtgtgc ttttccctgc
     5581 accgatcgtt cctgcaacaa tgatcacaat tatcggcatc cttcctgtaa taaaatctgt
     5641 tcttcatttt actacttcat ttatagaaat aaaagccttg actttatctg ctccttaaaa
     5701 gctacttctc taaaagtagc caaaagtaac tcctattcat gaaaataaag gctgtgacaa
     5761 aagtcttgtc gcagcccttt tttcaaataa acagtattct cctgccaaca cctcggtcac
     5821 aaggcaatat tcataaaaca tgaaaagctg ttttttaaca ttattccttg taactcagag
     5881 ctaaacggga gactcacaac ctctttatgc tctcaacatt ttatctgttt ttattcttct
     5941 attgtacttg atttgcgtac aactaactgc cagtgcagat tatgagcggt atcattgtct
     6001 tctactgcgc atttcatgac acgtatcatc acactatttt catagatttt ttctattttt
     6061 ccttttattg gtgattcaaa taaatcagat ttaaatgcat atgtttcgcc gacttcaaac
     6121 aattgttcat tttccataag aatccctcca tcacctttta taaggtcagt aattttttaa
     6181 cataaatcac tcgaaaaagc acaaacttgt cataaaaagt acttttcgta tcaaaactgt
     6241 cacttttttt ggtaaggttc ttggaaaacg aagatttttt taggagatca tgacggtttt
     6301 gatgtcaaaa ccacttttta tgaaacaaaa gacgtttttt atttttttta gcataaaatt
     6361 tgtggtggag gtacgtatga gatgaaagat aaagttgtga acaaattatt agaagcctta
     6421 ttcagcggag acaaatcgga agaagatatg gtgtatgtcc aagtaaaatt tgtcttagaa
     6481 gttttattga ataatcttgg aaaactagcg gtcgttctag tcttttctct ggtgacaggc
     6541 tcatgggcgg aaacaggaat cacctttctt tcttatatct gcatccgcag atatgcttat
     6601 ggattgcatt ccgactctga attcgtttgt ctgctgtgga cactacttta tttatggggc
     6661 gttcccttgg tgatgaaaca tctgcaattg actatctcct tcccaatgat ggtctttttg
     6721 ttaatcagct gctttttgtt actgcttcgc tatggatcaa gaggtacagc aatcaatccc
     6781 attgaacccg agaaacgtcc cccattatta aagaaggcga tcagcatgtt tctaattttt
     6841 tctctcatta cgttattttt ctcagcttct tacttttcta cctatttgct acttgggatt
     6901 gttttagaaa tagctacgtt gcttcctatt acaaactact tgatgaattt tggaggaatc
     6961 tttcatgaaa aaaacaatca ttaaacaatt aactaactta tctgactttt ttgtatctgg
     7021 ctgctgcttt ggtatgagtt ctgaattcaa aatccctgaa aaattaaaaa aataatacgc
     7081 caattgtgct ataatttggt aaaaatcaat gggagctgta ctttatgttt ttatggtcca
     7141 tagcgttgca atatttgatt tacacaattt gtatcttatt gattgaccat cacatccgat
     7201 acaaatatct gtttgcggga gtcattctga tttcttgtat tttgattgga tgggtctatt
     7261 cgattttagg gatttttact gctctaattg ctataggaat gctgatgctt acttttttct
     7321 tcttttcgac ttcgcgtcaa caattggttt acgcgcttcc ttttgggtta ttgacgtcgc
     7381 ttttaggaga tcacttaaca agcatcggcg atttttttgt tttgaaatct tcggttattg
     7441 aaccaggaga ttcattgcag tattttcaca ttgtcttatc cgctttttta tctgctttat
     7501 tagctttttg tttaaaaaaa tcgttagaga cttggtttca cactgtggac cgccgtatga
     7561 tcggtacgat cgggacattg atattattta catactatat cattattttt tatacccgtt
     7621 tttctggtga aacacctgat gtcttagctt tgaatacgag ttttttcatt ctatatctgt
     7681 gtgttggcct gatcatcttg gtttattatt ggaaaatctc taataagaaa ttagctgatc
     7741 agttattaga gcaacaagtc aggatgcaac aggattatat caaagatcta gaaaaaaact
     7801 atcaagactt gagagaattc aaacatgatt accaaaatct gcttttttct cttcacagct
     7861 atatttcaga aggcgactta gaaggattac ggtcttatta tgatcaaacg atattaccta
     7921 cacgccagat gatgaacctt tttccggcca atctaagtat gttggataat atgaaagttc
     7981 ctgagatccg tagtttactg tcattaaaac tcatgatggc acaggaaaaa gggttgatcg
     8041 tccagcttca ttttcctgag ccaatcgaac tggatacgaa acatacggta aaccttgtac
     8101 gtatgcttgg tattatcttg gacaatgcga ttgaaggagc tagtgctgca aagaagaaaa
     8161 aaatcgaatt gaccatactc aagaagaatc attccgtgat gattcgtgtg atcaatacaa
     8221 caacaaatac attaccgtta aaccagttga aacaaaaagg gttctcaaca aaaacaaatc
     8281 caaaaaacga aggccttggc ttgtttatct tggatgaatt gacaaagacc aatccttatc
     8341 ttttccttga aacatcaatt gaaaaccagc gtttttctca aacgatttat atacaaataa
     8401 aataaaggag taatgatatg attcccattt atatttgtga agacgatcca aaacaattag
     8461 aagttttatc aacggtgatc aaaaatagaa tcatgattga aaacttagac agttatgtcc
     8521 atatttctac ctctgatccg gaagaacttc tcaatgcagc caagatcaga acttcttctt
     8581 ttggtattta ctttttagat atcgaactag aagacagtga aatggatggt gtagcgatcg
     8641 gtaaattgat ccgtgaatta gatcctttag gaaaaataat ctatgtgact tcccatacgg
     8701 aaatgtcgat gaaaatctta aaaagcaaca tcgaaccgac tgattatatc gtcaaagaag
     8761 atctttatga tttaaaagaa aatgtcgagc atatcctgag caaaattttc gaagattttc
     8821 aaatgtccca aatccaaaaa gatatcttca aaatagagtt taatgatgag atcaaatttt
     8881 taccgatcaa agacatccaa tatttttcta cttcgctagg agcgccacat aaactggaag
     8941 tccatttgac tcatgcccaa ttacaattct atgagaagat caaagaaatc gagaaaatgc
     9001 atcggaattt tatccgttgt cataaatcct atgttatcaa tacacaaaat gtgcggtcga
     9061 ttaataaaaa aaccagagaa gtcacgttgg caaacggcga gaccatccca gcctctatcc
     9121 gtggattaaa gaaattgatt tcataaaaag aaccgaatag tttggaccga ctaaatgacc
     9181 agccgatcca aacccttcgg ttcttttttg cctatcagtg caaaagcatt tcctgtgcaa
     9241 tttcacgtcc atccattgta tctggataaa atgttggcca attctccatt tctttcagca
     9301 atacttcttg actttcattt cctgcatata aatgaaaatg ttcggagtca gccggtgcaa
     9361 tcgtgtgatc actgaattga atatatctaa aagcgccact ttccttatct tctgcttcga
     9421 atagatacct tacgccacgg tttcctgcct cgtaggtcaa gatttctttc cctacataac
     9481 gataatttga acgtttcgtt gttccattct taaacgtaaa tgccatctct ttctcactga
     9541 tcttgattga agcaatatct gtttgatagc ccttcgtata atattcttta tattcttgtg
     9601 ctgtcttatc ctgattcaat ttttctttat attcaaaaac aggatcaaaa gtcccatctt
     9661 ctacatacgt atctactgtt tgccaagttc ctgcccaatc tgaaagagag cgatcttgta
     9721 catcctcgtc ttcaaaataa ccgttgtaga cgctcttttc ttttttgggg gtcaaagtat
     9781 cttctagcgg gttttctgtc tctgtcgttt ttttcaacgc ttcgaggttt gcttccatga
     9841 tagaaagata gttttctcca ttttctattt gttcattcgt caatccttcc aaaggattca
     9901 atacttctaa agatacacct gcttcgtttg ctaacgttct ggcaatacta tctttggcgt
     9961 tttcttcaaa ataaatatag ttgattccat gttctttaac aaagtgtttc agttcagcaa
    10021 ttctcgccgc agacggttct tcactagaag aaagaccagc aatcgatact tgattcaatc
    10081 catattctaa cgctagatag ttgaatgcag catgttgcgt gacaaaagat ctttgttttg
    10141 cttgcttaaa ggtttcttga taaagctgat ggagtgcttg aagtttctcg gtataggctg
    10201 ctgcattttt tgtccatact tcctgttttt ctgggtaagc ttcaatcagc tgatcacgta
    10261 tgtttgctac ctgcttgatt gctaaacttg gagctagcca tacatgtggg tctagctcat
    10321 gtgtatggcc ttcttccccg tgttcatggt catgatcatg tccttcttca cttcccggaa
    10381 gtaaaagcat accttctgtc gcttttatcg tatggacatt gccttcttgt aatgtttttt
    10441 ggattgcggg gacccatgtt tccatgtttt catcattata aacaaagata tctgtatctt
    10501 ggatctttgc catgtcttta gcagaaggtt cataatcgtg ggaatcagtc cctgctggaa
    10561 tcaataactc tacttctcct tcatccccga cgattgcttt tgtaaaatca tacatgggat
    10621 aaaaggtcgt catcacgctc aatttttctt tactgtcctc ggctttccca cttgccccgc
    10681 aagcagttaa catacctgct aaaaccagca tggccaatat acctatcaat cgtttcattt
    10741 atgacactcc tcttctcatc ttctttcatt tgaatgttcc gattcgcttt tcgcaaaccg
    10801 taatagttac gttttagcaa caggatttaa tttatcatat ggttaaaaga actgtcaagc
    10861 gttttcttat tttaattgat gagaaagttt atatgaatga ttgacgatat ttttgcaatc
    10921 aacctctatc attttccttt tatacccgct tttgtctata atgaagttat agataaagga
    10981 ggaaaaagag tgaaaaaaga aacagataca acgaatcgtt tgatccgctt tttaggagga
    11041 aaaacctctt actatgtttt aggaatagtt atcttacttg cgctgatcat ttattttttc
    11101 catcagatct cgtttatatt caagcctgtc ggaatcatta tcgctactat cttgccccca
    11161 ttattgtttg cactgatctt gtattatctt ttggaaccag tcatcaaacg tttgagcaag
    11221 cacctttcga ggaacttgtc agtcattatc gtttatgtga ttattttatt tttattgggg
    11281 cttggaagca tatggcttat tccttttctt gaagaacagg caaagacatt gatcagtagt
    11341 ttgccagatt tgtttcaaga ttttcaagag agtctccgac aatttttgga gaaaacacct
    11401 tttgccgatt catttaatca atttttcgct tctattgacg acgtgacgtc tgatatagct
    11461 ggatttattg gaaattattg ggaaagtggc gcacaacgga tcagcaacat tttttcaact
    11521 gttacagcta tttttattac tttatttact ggtccaattg tcgctttttt ccttttgaga
    11581 gatcctcaaa aattttatca gtcagtttta gcgattgtcc caccagcatt tcgtacagat
    11641 tttaaaaatt tgacaaagat tgctaatcaa caattgggtt catttctaaa ggggcaaatc
    11701 attgcttcat ttatccttgg agcagtctac tgggtttgtt tcttactgat cggattagaa
    11761 tttgctagtg ttttagctat ttctgctggg ttgttatgta tcattccata tattgggccg
    11821 tttatcgcct tctttccagg tttgatcatt gcattccaag actctacttt tatggctgtc
    11881 aaatttgtca ttgtctggtt tgccgtacaa cttctccacg gtgacttggt gattcctcga
    11941 gtaatgggtg atcgtttaca gatccatccg attacgatct taatcgtttt acttgtcatg
    12001 ggtgatctaa tgggaattgt gggcgttatt tttggtattc ctatctatac gttagtcaaa
    12061 ttactcgtta cttttatttt ccgtaaattc aaacaacgct acaataaatt ttatggcgat
    12121 aaaggagagt atgaaaactc ttcattttct gaagaagatt attttaaata aaacacaaaa
    12181 cgtcgatctt acgagaatag ctcgtaggaa cgacgttttg tgtttttgtt ttaatttttc
    12241 agcaaagcaa ttgcctggta tggttttagc tccagacttt gatgaagaac agtatcggaa
    12301 taattatcga taagaatatt ggcttctgtg aatccttctg ggatggcgat ccttgtatct
    12361 ttatcataga aatttgttaa tacaagcagc tgctgtcctt caaattggcg aagaaagcca
    12421 taaacttccg gatgatttgc ttcataagca tgataatctc cttgtgcaac gattggatat
    12481 gtttttctca gccgaatcaa tttcttgtaa taggacaaaa tagaatcttc agaagatagt
    12541 tctttttcta cattaatctc ttctagcttg cctccaactt ttaaccaagg tttccctgta
    12601 gtaaatcctg cttgttctgt gtctgaccat tgcatgggtg ttcgagagtt atcgcgagat
    12661 tttgctttga tccgacgaaa cgcttctttt tctgtgaatc cttgttcaag gagtaactta
    12721 taagcattca aactttctac gtcaatatag tcggaaatcg atgaatagtc tgggtcgatc
    12781 atgccgattt cttctcccat ataaatatag ggcgtcccac ggttcaaatg gatcatggtt
    12841 gctagcatct ctgctccttg ttttcgatac tgatcgatag ctacaaatcg attgagcgca
    12901 cgtggctgat catgattatt aaaaaataga gcattccagc cgttaccctc actcatcttt
    12961 tctccccatg tatgaaatag tcgctttaat tctgcaaaat caaatggagg agtagaccat
    13021 ttattcccat tttcataatc gactttcaaa tgatggaaat taaagaccat tgataattct
    13081 tctctactag gttctgtata caagatacaa ttttcgatcg tcgtagagct catttcaccg
    13141 actgtgatga tagtggaatc cgtcccaaac gttgcttggt tcaattcttt tagatacgta
    13201 tgggtgattg gtttgtccgt atattcaggt ttgccatcat tttctttatt atttttcaat
    13261 tgttcgtctt taccgataac attgataaca tcgaaacgga atccttttac ccctttttcc
    13321 atccaaaaac gaacaacttt gaatagttcc tctcttactg cttggttccg ccagttcaag
    13381 tcagcttgtg tccgatcata taagtgcaaa taatatttcc ccgtatctcc aaatggcgac
    13441 caagcacttc caccaaattt tgatacccaa tccgttggct cttctcttaa aatgaagaag
    13501 tcctgataat gctggtcccc tgctagtgct tttttgaacc attcatgttc tgtcgaaacg
    13561 tgattcagca ccatatcgag catgatttct atccggtatt tctttgcttc ggctattagc
    13621 tgttcgaatt cctccatcgt accaaagata ggatcgatgg ctgtgtaatc agagatatca
    13681 taaccgttgt ctttttgagg gcttggataa atagggttta gccaaatcat gtcgatgcct
    13741 agatcattca gatacgggag tttttctttg attcctttta aatctccaat tccatcacca
    13801 ttactgtctt tgtaagattt gggatagatt tggtaaatga ctttgtcttt aaatgtcatg
    13861 gatatttacc tccattcaac tgatttatta cctaccacaa cttatatata caagttatca
    13921 tttattatta taactgaacc gaaagcgttt gtaaaattta tctttataca ttctaagagg
    13981 tctgttgccc aataaaaaac aagagatcag acatgtattt gtctatcctc ttgtttaaaa
    14041 tagcaaaata ttcttgtttc ttctataaat ggtgttcaaa agcttttatc tacggcaatc
    14101 agtcttctca aatgtaaaac atgaggagct aattttattt gagtattctt tttgctcgat
    14161 gcaggacggc ttttttacaa cctctgattc atggtgttca atcagctgtc cttcggtatt
    14221 agctcaaaaa acggcaaaat atgaaaaact attttgccgt ttgtttctct aatactcagg
    14281 tcaaaccgct gatttcacaa cctctgtttt tattcattcg atttcaacgc atcaatcata
    14341 tcgatatgct ttaatttgaa atgggtaaca atcatcacaa taaccgtaaa tacgatagtt
    14401 aatcctgctg ataagacata agcccaccat gtgatcacta atggaaagat gacattctcc
    14461 atagacgctt gttgcaagat gaagtcagtc aatatatatc ctacaccaaa tcctccgatg
    14521 attcctaaaa gagtaaagat gatattttct cgaacaatgt acatcgtgac ttctttatca
    14581 aaaaatccaa ggacttttat tgtagataat tcgcgtacac gctcggaaat attgatatta
    14641 gttagattat acaagacgat aaaagccagc agtcctgata atacgacaaa gattaagaca
    14701 accgagtcta agttcgccat tgattcttct tgcgtttcga tttgtttgga catgaaagac
    14761 gtatttgtca cagcgtctgt ggcaagcagt ttctcggaaa gcatttcttc ttcttttgtt
    14821 gtcatcttat ctgtacgcag caaaaatgca ttatccatca tcgattgatc agtaactgaa
    14881 gcataatatt caggggacat ataaataaag ctacctagat agtttttcac gatttctttt
    14941 acttcgactt tccattcttt ttgatcttca tcataaagcg aaatatgatc tcctgtagat
    15001 aagtcaaata gttctgctac tttttgcgta atagcgattc ctgttttagg caaggagcgt
    15061 gggttctctt caagatcagt taaatggata aaacgatcca aatcagctgt tttacttggt
    15121 acgatcactg tcagactttg cgaagcatgt cctttttttc tcaattctac ggtttgagta
    15181 tgaatagcta ggatctcatt tactttttct tgcttctgca gcatatccgc tgctttttga
    15241 cgactatctt ccgtggatga atccaatgta acgattgctt gatagtcaat gatcggtcca
    15301 aattgtttgg ctgaaacaga acttagagaa tctttcaatc ccacgcctgc aaccatcagc
    15361 ccggcacatc cagcaattcc gataatcgcc ataagcattc ttgacttata tcggaagaga
    15421 tttcggtaac tgattttttg attaaagcta aggcgtgacc acagcggagt gatgtattca
    15481 agaaaaatgc gtttccctgg cttcggtgct ttcggttgaa gcaatgcagc aggccgttct
    15541 cttaaatctt tgaataaaac gatcattgca gcgccaaatg cggcaatgaa gaatgcggca
    15601 gctgcttgta aaatcggcgg ccagtcataa aaaataagcg cactcccaat atcataccgc
    15661 tcgttagaca gctcaaaaat gatccttggc aaaagattcg ttcctaatat cgttcctaaa
    15721 acaataccta tccctgaggc tagacttgca tagattgcat atttttttgc gatttcaact
    15781 ttcgtataac ctaacgcctt taatgtcccg atttccctgc ggttttcttc taccatacgt
    15841 gtcattgtcg taaaggtgat caatgcggca ataaagaaaa agaaaacagg aaaaacattg
    15901 gcaatcgcag cgatacgatc agacagatca ccaaattctt gaaaaccgac attttctgaa
    15961 cgttcattgt ataggtatga tggtttagtt aaattttcaa ttttttctgc atttcgattc
    16021 aattcttcct ctgcagaggc cagttcacgt tctttctcaa ctaattgcct ttcttgttca
    16081 gcaagttgag cttcttgttg agataatgtt tgaacagcga ttgttcgttg cgcttcagga
    16141 agctgctgga tagttgctga ctgttgcgct aactgttttt tagcatcttc taaccgtgtt
    16201 cttgcttgcg ttgtttgtgc tttgccatcc gctatttttt gctgtgccgg ttctaattct
    16261 tcgttggccg attttttcag ctcttctaag cgttcttcgg gtcgatcttg taaatacttt
    16321 tctgcctttt cttgattttg ctccatttta tctttgtaag ctttgctgta cgtattcaaa
    16381 ttctttacgt ttgtaaaatc aagatataag acagaataaa tatctgtttt aaaaacggat
    16441 tcaggtaaat agacaaaata atcgacgcta ccatttccga cgttcgcgta tcctctctcc
    16501 aaattgttga tgaacaatgg agaacggaca aagcccgtga tggtatactc tttttctttc
    16561 aattcatctg aatcaatctg ataaatatca ccgattttat acccttcatc ttccgctttt
    16621 tcatccaata caagctggtt tggtttttcc gggagttttc catcagttaa ttgtagcttg
    16681 ttctgcttgt tatttttgtt ataagaaaat atttgaatca cttcgttttt gccagtattg
    16741 gaataataga tctgttttcc tgtttctact tttgcatctg ggatcttttc tgcttgagca
    16801 atatcttttt gtgtcaagcc accagtagaa acgatttgca aatcagaaag tcctgctgta
    16861 ccaacatagt gatccatcgt tttttgcatg acaggtccag cagttttgac acctacaaat
    16921 aaaagtgttc ctagcatgac aataaggatg attgcaatga atcgtccttt agattgccga
    16981 atttcgcgaa aacctgcttt aagatatgtt cttgttttca taaaatcccc ctaccataca
    17041 atctcatcaa tggatgaagg atgatcattt aattcaacag accttacttt agcatcatta
    17101 atgtgaatga ctctatcagc gatgggcgct aaagcagaat tatgtgtaat gatcaaaacg
    17161 gtattgccgt gttgtctgct agcgttttgc aataatttca atacttgctt gcccgtttca
    17221 aaatccagcg cgcctgtcgg ttcatcacat aaaagaagtt tgggattttt agctagtgca
    17281 cgagcaattg aaaccctctg ctgttcgcct cctgataatt gggacggaaa gttattcaat
    17341 cgatgagcta ggcccacttg cctcaatacc tctacaggat caagcgcatc aggagaaact
    17401 tccgttgcca attccacatt ttcttttgct gttagattag gaacgagatt gtagaattgg
    17461 aaaacgaacc ctacatctgt tcgtcggtaa gcagtaagct gtttatctga aaattgcgca
    17521 atatctgtgt catcaataat gatctgacct tcatcaggtg tatccatccc acctaaaata
    17581 ttaagaatcg ttgactttcc tgctccactt ggaccaagta taatcactaa ttcgcctttt
    17641 tcaattgaaa aagaaatatc gtcatttgct gtaatggtcg tttctcccat tttgtatcgt
    17701 ttgtattcat tttttacttc gacatacttc actctgattc ctccattttc acgatatttc
    17761 tcgctatatc tatgcatcga atgcgttttc tcacacttat ttattttacc actgaatttc
    17821 tctagactaa agaaaggaat cctttaattt agttgacaaa taaacgattt atgatttact
    17881 tacataaaaa acattgttat ttgaaagaag gaacatcatg aatgatttaa aggaaaatat
    17941 gatttttgat ttatcaaaaa ctgcttttgt cgcgatcgac atgcaaaaag agatcgtaaa
    18001 taacggtaca ctctctccac acactgcagc atctattctg acaaacaatg atttgttagt
    18061 aagaacattg aaacgtaccg ctgccttgaa agttttagtg aacgtagaca tctccacttt
    18121 cccttatttg agtcaacaaa ctgatatggg tggaatgact gcttctgtac ctccagaatt
    18181 cactgattta cttttgaagg attctttgaa agatacagat aatatgttga ctatcacaaa
    18241 atacaatcca agtgcttttt ttggtacttc tcttgatctt caacttcgcc ggcgtggaat
    18301 cgaaactatc attttaagcg gtgtagcgac aacaaacggt gtatatgcta ctgcattaga
    18361 tgcctttcaa cacgggtacc atatcgtgct tgctgaagat gcttgcagtg atcgtgacaa
    18421 agaatcccat caattgttca taaaaaagat atttccgaaa actgcacgag tacgctcaac
    18481 gaaacaaata atcgaagcta tccaacaaag caaataagta ctggcacacg tgattttcat
    18541 ttacttcttt ttgatttcat gggaaaataa ccacaggatt tagataggag tatgaacatg
    18601 gtgaaaaaaa agatcacaat caaagaagtc gctaaacttt ccggcgtttc aatcacaact
    18661 gtctccttga tattaaatgg aaatacggag aaattcagtc cgaaaactgt tcagaaagtt
    18721 ttagctgcca aagaagaatt aggctatcag cctgactatt ttgctagaca aatgattacc
    18781 aaggaaacga aaacaattgg tgtactcgtt cctgatatca cgaatccatt cttcagtaca
    18841 ctgatgcgag gaattgagga tatcttgtat aagcagaatt tcgtcacgat attatgtaat
    18901 gctgattctg atcatcaaaa agaaatcgaa tatctagccg agctcacacg tcgaggtgtg
    18961 gatggattca ttatcgcgac ttctgctgtc tctacagatg caatcaacga aaatttgaaa
    19021 aaacaaggcc ggcccttcat tgttttggat cagaaaaaat ctgaaggatt tagtgatgcc
    19081 gtacgaacag acgattttcg cggtggttac ctagcgggca tgcacttgct tagtctagga
    19141 catcaaacga tcgcccttgt ctatcctgaa aatccaccgg aaaatgtcca cgctcggatt
    19201 gaggggttta aatctgctct tgatgtttac caaatccctc acgaccaact gatcctctta
    19261 cctacacagt tctcaaaaca aggtggctac cagatcacag cagaacttct tgattctgct
    19321 gcaactggtg tgtttgcttt aaatgatgaa ttagcttttg gattatatcg cggattagag
    19381 gaagctggaa aaagcatccc tgaagactac agcattattg gctatgataa tatagatatg
    19441 tgcgagtata tcaagccgaa actgacaacg atcgcacaac caatcttcga attgggacaa
    19501 acatctgcca agttattgtt agatcggatc caattcccag aaaaagaatg ggaagaaaaa
    19561 agattacctg tacgattaga aaaaagattt tcaactgcac ccttgaaata gctttcaagg
    19621 tgtgctatat ttttatcgaa ctattaaaac gttttactaa aacgttttaa aaaataattt
    19681 tcccatcaaa ataaatgaga tagttggagg tttgtaaaat gaacacggtt acagtaattg
    19741 gaagtattaa tatggacact acccttcgtt taaccaacat gcccaagcca ggcgaaacga
    19801 tgcatgcgca tgagattttt cacgctggcg gaggtaaagg tgccaaccaa gcagtggcag
    19861 ccaaacgttc aggcgcacgg acatctttta ttggaggcgt tggggctgac agcgaaggac
    19921 aacagttatt agatctactg acaaaagaaa acatcgatac atctgggata gctgaaatcc
    19981 aaggcgccac aaccggacaa gcaatgatta tggtagacgc agcaggagaa aatagtatct
    20041 tgatccatgc aggggcaaat aatgctttcc atgaacaaga agtcctaaaa aacaagcaac
    20101 tgattacaaa cagtgacttt attattgctc agtttgaaag tagcttagat gcgacgatcc
    20161 tagctttttc tattgcaaaa gacgcaggaa aaacaacgat cctgaatcct gcaccagctc
    20221 gtgaaacgat tcctactgaa ctacttgaaa agacagatat cattatacca aatgaaacag
    20281 aaacagaaat cattacagga atcagagtga cagatcataa cagtttggtc gcagcagccg
    20341 aaaaactcca tgaattaggt attggaacag taatcattac actaggcagt gccggcgctt
    20401 tctatcatac agaaaaagaa cacggtatcg tccctgcttt taaagtggat gcccttgaca
    20461 caacagccgc aggtgataca tttattggcg cattaagcag cacacttcag ccagacctta
    20521 gtaacttgaa agaagcgatc ctttatggaa atctagcctc ttctgttgct gtgcagtctt
    20581 atggtgcgca accttctatc ccttaccgcg aagctttaga acaatcagca gtctaaaatt
    20641 aacaatgaga ggaagaaaca aacatgaaaa aaggaaaagt aatcaattca gatatttcac
    20701 gagtaatcgc acaaatgggg cactttgata aattaagtat cggggatgca ggcatgcctg
    20761 tcccctttgg tactgaaaaa atagatttgg ctgtctcaaa cggtcttcca agttttttat
    20821 ctgttttaga aaacgtttta gaagaacttg aggtacaatc gattgaattg gcggaagaaa
    20881 taaagacaat gaacccggaa atattggaaa aaatcaaatt attgttacca gatacaccga
    20941 ttagctttat cccacatgaa gaaatgaaaa aagagttgaa taactgtcat gcatttattc
    21001 gtacaggcga aatgacacct tacgccaata ttatattagt gagtggagtg gtcttctaat
    21061 ggaaacgaca atgaatcctg aacagatggt actgtccgag cagattcata tgctgattga
    21121 acagttggga ggaaaagaca atattgattc tgtccttcca tgtgcgactc ggcttcgtat
    21181 caaattgaaa aaacagccag tagccaatgc agaaaaatta aaacagcaaa tcccttccat
    21241 taagtatttc attttactcg atagatatgc agaaataatc atggatcagg gattggctcc
    21301 tgcttacaag gaattgacgc gtcaaatcga tcattcagct ccgaaagaaa agctaaatcc
    21361 gatcgaaaaa ctatttggtt tgatatcgga aatctttacg ccgatcattc cgctgtttgc
    21421 cggttctggt atattaaaag gtctggttgt tttagcgact acgattggct ggcttagtga
    21481 aacaagcgga acttatcata ttttgtctgc tgcgtcgaat gccgtctttt attttctgcc
    21541 aatctttctt gctttttctg ctgccaaaac gtttaaagtg aatggatata ttgcggctgt
    21601 cattgctgca gcactgattg aaccgaatct gacctcttta ctttcagaca gtggcaaagc
    21661 agctactgat tttctgggga ttcctgtagt actgatgcag tatacgtcta ctgtcatgcc
    21721 ggcgatttta ggtattttct tttattcttt tgttgaaaaa ttcctcaaaa aatatattcg
    21781 cgaaaatatg caattagtat ttgtaccttt actttcatta gttatcacgg ttcctttgac
    21841 gttaatggta ttcgggcctg cgggtgttta ccttggcgaa ggtttagctg ccgcaattac
    21901 ttggatgatg gatattaacg gaccgatcag tggcgcaatc atcgctggtg gttggaatat
    21961 tttggtaata tttggtatcc aatgggctgt aaaccctgtc atgatcagta atatctctgc
    22021 ttatgggttc gaccgaatcg ttccgttgac aggagcagcc aattttggaa tggctggtgc
    22081 agctttaggt gtatttctgc gaagtaaacg ttcaaaaacc cgttcgatct ccggttctgc
    22141 ttttgcttcg attttacttg cgggagtgac cgaaccaact gtttacggaa ttgcgatccc
    22201 attgaaaaaa ccatttgttg ctgcttgcat tggtgcagct gctggtggag ctgtaatggg
    22261 atttgcccaa gtgaaagcga tcgcttttgt atttggtagt ctgaccacat tgcctgcatt
    22321 catttccggt acttttttct ggtacttagc aggactggct gttagtctag tcgtagcaat
    22381 gatcactact ctcgttagcg ggtttgatga agacctaatg tcttatgaat agttaatgaa
    22441 aaagactgaa gtatgagatg tttatcacat atttcagtct ttttcttttt aggatcatta
    22501 tttttataaa tttttgtgat actttccaaa ctttggtata atttacatat gcataaccat
    22561 ttttatcccc acttgtttat ccccaaacaa aggtggtcta tgcaataaaa tgaacgtcaa
    22621 agaaaaacga atgaatgctc gttgcttatt tacaaattgt tttatttaga atacacagac
    22681 agatttatga aaagaaaaag cttttcgaca cgattatctg ttccaaaaaa tgtctaatga
    22741 atgctgaata agacagaaaa tcaatgaaag gaaaaggact agtttattat gaaaaataaa
    22801 aaaacgatac gtttgctagc tgctacttgg ctgattgctc cgtctgtttt gtcgaccaat
    22861 accgtatttg ccgtagataa tcaaatagct gatcaaacag tcacaacaga tacgactaca
    22921 tccagctcag ctactagtga aacaacggat tcttttacag aagacccaac tggaacaact
    22981 aactcaacaa caggatcgac cgagccaact gaaattgatc cggctgatcc atcagaaaat
    23041 gaaaagccag ccgagacata ttcccttaca attgctcctt ctttgattgg taagatccaa
    23101 ctgactgctt cgacagcgga ttcccctgaa cagcaacctt tggatattac ggaaagtgga
    23161 acggtagaag gtttattagc ggaaacgaag gtaacttaca ctattacgcc agctgaaggt
    23221 gaacaaattg cttcagtcgc tgttaatggt gccaaagaag taaattatga tgcaaagacc
    23281 tttacagtag gtacgaacaa tttatctatt actgcagaat ttaaagctgg accggatact
    23341 tcaacagaga aaccaactga tcctagtgaa gaagtcccta gtacaccaga tccggaaacg
    23401 ccaaacaaac cagatgtggg taataacaac aataataatg gttcaaataa ttcaaacaat
    23461 aataacaata attcgaacag cgggaattct tcgaatcaaa caaacccatc tggatcgaat
    23521 aacaatggaa atactcagag agaaccaaac catccaaaca atggttcatc gaatggcgga
    23581 acgaacaatg cttcatctcg tccaaataca gcaaatcaaa gcggtataga gaatccatct
    23641 tctgcttctt ctgattttgt tgtaaaatca ccaattgatg ctgtattgcc tacaaataca
    23701 acgaatgtcc aacaagcaat cgttcgagaa gcattcaagc atcttggaaa accatatgta
    23761 tggggagcaa aaggtccaaa tacttttgac tgttctggtt tgacttatta cgtatatatg
    23821 aaagcaaccg gtcattatat cggtggctgg acaggcgaac agcaatatgc aggtacgcag
    23881 attccagtaa gtcaggccca acctggcgac ctcgtcttct ggggaccttc ttccggtgtt
    23941 actcaccatg taggtatcta tattgggaac ggacaattta tccatgcgcc tcaaccagga
    24001 gataaagttc gagtaacttc tatttcagat ttcacgcctg attttgctgt ccgagtaaac
    24061 ttagcaggtt tacctgctgc ttcaggttcg ctgacaggcg gctcatctat tttagatgga
    24121 ttagatggct cgttccattt cagtcaaaac caaacaactg atcagttctt gaaaaagatt
    24181 gcagatgatg cacaggaaat cgggcaaaaa gaaggaatct acgcatcagt catgatggct
    24241 caagctatcc ttgaaagtgg atctggaaac agcttattat caagcgaacc aaatcataac
    24301 ctttttggta tcaaaggatc atataaagga agcagcgtga ccttcaatac acttgaacaa
    24361 gatagttccg gacaaagcta ccaaatccgc gcacaattcc gtaaatatcc ttcttacaag
    24421 gaaagtttgg aagactatgc cgacttgatc aaaaatggac tgactggcaa tcctgatttc
    24481 tacaaaccaa cttggaagtc ggaaacaaaa gactacaaag aagcaaccaa atatttggaa
    24541 ggacgttatg ctacagatcg ccaatattca caaaaattga acgcgatcat cgaagcgtac
    24601 gacctgacaa aatatgatga accgaaaaaa gaagcagcaa caactgaaga agcaaacgct
    24661 gaaatcctca atatgtctaa gcgattcgat gtgccaatca aatggacaac agatggcgtg
    24721 ccaatcacag gattagaatt ttcaacgata aaacgcgtca acaacgcttc ttccatcttc
    24781 cgtgtcgctt caatctggga tttgtggaac aattttacgg caagacagat accagaaaca
    24841 actactcgta cagttaaagc tgcaactgtt cctgtactaa ccttgttaag tttagacaaa
    24901 tcattctggc ttgatctgcc tttaaagaaa tagaataaat taaaaagggg atgtgacact
    24961 gtcacactcc ctttttaatt tattctattt ctttatattt attttgtatt ccgttacaaa
    25021 ctcgcgtact tggttaggtt ccagagtgac atctccaaaa ctttcaagtc gctccgctcc
    25081 tggcagttct tgagtctcaa atgtgatacc gccatgattt actaatttat tcccgcgcat
    25141 ttccggtcca tcttctccaa aatttgctgt aaaaatcacg attcctgaag catctgtttt
    25201 tacttggatc gatacttttt catctgggct tgtcaattcc gcagcattta gtaaaccaga
    25261 ttgttttttc aacaaaaatg gatgatcgat gccgcccact atcattgatt ggcgaaaatc
    25321 actggcaaag acctcaccta attttttagg acgttggaag tcaaatgctg tgccacttac
    25381 tgaaactact tctcctgtag gcgttgtatc tttattgagc gtagcaaata atcggctatt
    25441 caaccaaagt atatgttcgt cgattgactg tgctggatca ccggttaaat tgaaatagac
    25501 atgatttgta ggattgaata ctgttttgcg gtcactgatc ccttggaccg tcactcgcca
    25561 tgtatcatcg ttcgtcagcg tataccgtac ttctacatct aaagttccag gaaatccgtt
    25621 ttccatatct gggctagtct gatagaaaat gaccgatgct tcgttttcac cattgatgac
    25681 tgtataatgc cactgcttgg cttcaaagct aggtgcacca ccatgtaaac aatgaccagt
    25741 gtccgggtct gtttttactt cgaacgtttc atcatctaat ttgaatgtgc cattcgtaat
    25801 ccgtccagcc atacgtccga ttgaagcacc gatataaggg tctttttcta gatattcttt
    25861 tgcttcatca aaacctaaga tcaactctcg tttttcatta tcgattattg tttgaaaatg
    25921 aacaacccgt gccccaagat cactgacaga caaagatgtc ccattttgat tcgtgatcgt
    25981 aatcaagtga tagttttcgc caaaattttg ttcattgatt tccatgttcc ttgcaccctc
    26041 ttttctttca tttgcactga ttccagtata catggaaacc gttttcttaa cagcttattc
    26101 cgtgagtaac gagaaaaaat ttactatatt ctaataaaag accgtgaaaa aaaggttgtg
    26161 acaaaaatat tgtcacaacc tctttttccg aacaaacggt gttcaaaagc ttgcatctgc
    26221 ggtaataagc ccaaccaaac gaaaaatatg aggagctatt tttgcttggc tgttcttatt
    26281 acttgatgca ggacagcttt ttcacaatct ctttttcaat acgattccag tatataacca
    26341 tgtcgtcagt acatagtaga tgaaatacaa tacgaagaat atcgtaaacg gaacccaaat
    26401 atctttgtat ggattttgca tgaatagacc aaacatttgt aatccgaata agacatggac
    26461 tacacctaag attcctggtg ctaagaataa cacgcctact tctctacgga tcgattgttt
    26521 aagcaacccg cgtcgtgttc ctatcttttc aagcatttca taacgagcaa tgtcactctt
    26581 gcttcctgac aagatcttga acatcaaaca gctagcaagc atggtcaaga aagctaaacc
    26641 taggaagaat cccataaatt caaaaccaga gaatagacca ttatacactt catacatttc
    26701 atatttctgg ttgctgtact ctactttttg caaagatgga ttgttcattt tattttgagc
    26761 aacaagtgtt tcgattggtt tcaggtttgc ttggaagtct tttacctgaa ctagctgtaa
    26821 agtggattgt ggcaagttca gttgatcaaa ttctgattga ctgactacct tgatttcttt
    26881 ttcttgctgt tccggcaatt catagcttcg aagttcctct tgtacagtca gttcattcat
    26941 ttttttagca ggaacttttt ctttcgtgat cttcggcggt gttccatctt catgttttat
    27001 catgatcaat ggttgagccg caaattcact tgcattatag taaatcgttc ccgcatcttc
    27061 tttttgagta taagaagcag aaagtgttgg tgaaagttct ttgatttttt gctgatcttc
    27121 tgcccgagga ttattcatca ctagatcata tccagaattg ttttctgtca agtctgcaat
    27181 ttcattttta aaacctaatc ctaccgtcaa agcgcccagt gccaaggcaa acagcatagc
    27241 gaccattgag agcatttgtg tatattcacg aatacgaaag tttaactgtg acaatgtgaa
    27301 attgttcaat tttttcaatg aaatctgttc tgatttcttt agtaatgata aaaagaaaat
    27361 gatcacagaa tggaaaatga aataagttcc taatacgatc gtaactaagg ctacccctat
    27421 accaaagact tgataggtcc ccacgtgttt catcatatag taaccgcagc ctagaaaagc
    27481 aattcccagt actacttcaa ggaaaaacaa gaatttatgc tgcttgattc ttgttggtgt
    27541 ctgatccgca cgaatcaatg ctaaaatcgg ttttttgaca atcgaaaaag cattgacaac
    27601 agcagctaat aaaaacaaaa cagcaaaaaa caaaacagtg atcaacaacc cgtgaatact
    27661 aaaaggtgta aaatgcgaaa tattgagatc taactgatcc actaataatc ggtggacgat
    27721 acttgtcaat cctacaccga cagctgaacc cactaaagta gctgcgatcc ctactaagaa
    27781 tgtttcagaa aaaatcatct gtgcgatttt tctgcctttt gctcccagca tcataaacat
    27841 tgcatagtct ttttgccgca tcgtcatcaa aaaggaattt gcatataaaa tataaacgaa
    27901 tgtgatgatc cctagtaaaa cagaaccgaa tcggaaaatg ataactgtag ccgcaacgat
    27961 cgtattactt ttcaaaaaag cttcgttgct tgccattgat tcaaacatgt aaaaaatagc
    28021 agatgccata actaatcctg agaataacac caagtagtct cttaaacggc tcttgatccc
    28081 agtaagtgat aatttccaaa gcatagtcaa tctcccccta ctgttccaag tttccaagaa
    28141 tagatagtat ttctcgatag aaggaatcac ggctttgatc tccacgtttc acttcttgat
    28201 ggataccgcc atccttgatg aataaaatac gttggcaata acttgcagaa aacggatcat
    28261 gcgtcacaag aagaatcgat acatgatctt ttgtattcaa ttcgtccatc gtatctaaaa
    28321 gatcccgggc acttttggaa tccagcgcac ctgtaggctc atcccctaat agaatcgttg
    28381 gttgtgtgat caatgcacgt gcggcggcga cccgttgttt ttgtccaccg gaaatctcag
    28441 aaggatagct ttccaaaata tgagagatgg ataaacgttc tgcaattttt tggacacgtt
    28501 gcttgatttc ttttggtctg acgccttgta aagaaagagg aacagcgata ttttcttgtg
    28561 ctgtcaagct ttctaataaa ttgaaatctt ggaaaataaa gccaatctca ttcgcacgaa
    28621 aatctgctag ttgatttcct tttaatgtgg tcacatcttt ttgattgatt cggatatgcc
    28681 catctgttgg tttatctaat gtggataaaa tattcaaaag tgtcgactta ccagaaccag
    28741 aagcgcccat gatcccaata aattcgcctt tttctacatc gaagctgatg ccgcttaatg
    28801 cttgcgtctt tttctcattg ttttttccgt atacttttgt tacattctgt acttcgacta
    28861 ttttgttcat ttctttccct accctttaat tagtttttcc agtgctgttt tcggcacgtc
    28921 ttttttttcg acttcttcat acgaagtgac acctttattt ttgttccagg tgatttttaa
    28981 atatgctcct ttacgaagcg gtcgagtcaa ttgtcccttg aagtccagtt ctttttcctt
    29041 accctctttc gtatagccag gcaggatata tctatagttg actgtttctt gtccagagtc
    29101 tgattttgaa actgtttttg taccatctgt cgtaatttgt acatagtatt cttctccacc
    29161 cataactacg taatctgcga ttttcacccc tgcaagtacc acaacgatga aaacaagtag
    29221 accgatcaga agttttttca ctttttcccc ttctctctta ctttatatac tgattataga
    29281 aaaaagcgaa caattctgcc ttcgaatcaa ctatcattct tctttcaatt ttgtcatttt
    29341 ctttaaaaca actaaaaaaa gagttcaaga caataatccg tcctaaactc cttcttccta
    29401 tcttacaaaa agtatgtcac ttacggtctt tcatgtcgcc tgtattgata acaggttgcg
    29461 ttcctttgtc tgtaatgatt gagacaagta aattattgat caattggact ttccgatcat
    29521 cggtgaaatt gatttcttgt ccatcttcga tttgctctaa ggccatttga gtgattgtga
    29581 cagctccttc aacaatggtt tgtcgagcag acaaaatggc ttttgcttgt tgacgttgga
    29641 gcatggcact agcgatttct gttgcatagg ctaaatggtt caagcgtgtt tcgattactt
    29701 cgacacctgc tactgctaaa cgctcttgca gctctttttg caactcgtca gacactgccg
    29761 tcgtgtttcc tcgaagcgtc aaatcattct cattgaatgt atcatacggg tattggctag
    29821 cgatatgccg aatggctgtc tcactttgga tttctacaaa atcttgataa tacgctacat
    29881 cgaataatgc ctttgctgta tcaacgactt taaagactac tactgctgag atttcgatgg
    29941 ggtttccatc caaatcattg acttttaaaa cagaactatt gaaattccga actttcaacg
    30001 aaacagtcat tttttgtgcc aaaggtatcg taaggaaaaa gccattttct cgaatcgtac
    30061 ctaaatattg tccaaaaaac aaaattactt ttgcttgatt aggactgact acagttgccg
    30121 aacttaacaa caataacgtg atcaaccaaa gaaaaatact taaaaaaagt gcccaaactt
    30181 tcgcttgcca catacctaaa tagaagaaaa acaatccaac taaagctaat acgaccaatc
    30241 cgacaatccc tgcataacca ttgatataaa atgctctttt ttctctcatg ctacttcctg
    30301 cgctccttta tccttcaata aatatctaat gttacttttt taattttttt ttcgaatacg
    30361 cgccattaca ccttctagtt ctaactcttt gtcttcagtg atgtaccaac cgcttgcctg
    30421 tgtccctccg gctgcctgcg gtaaataatc caattttgtt cgaacccagt gcttttcttc
    30481 tgtaaaatag tcttctacca agacctctag atccatccct gctgaaagag gcaaatcttc
    30541 ccgaacagat ttaaagataa atcgttcctt cttcccatca tacttcaata ttcctgtatc
    30601 gataatcggt aaagaataat aatccagctc tttcttcacc gtcaataaat gtttgaaaac
    30661 ttcatggtac acttgctcta attggcgacc ttctgaattg ttcgggtaat taaccatcac
    30721 tttttctttg tctggatcat agaaggtttg gcttagttga gtgatataag tatgtaatct
    30781 ttccatttct gtttttaact tttctctttg accttcttct accttcatat actctttcac
    30841 cctgttttct ttttagatat tttctttctt attttactat agttatgtgc gttaagcgat
    30901 gaaaaacagc aaagattgga aggatctttg ctgttttttc ttaaaatatc cagttgagta
    30961 caggatcaat ctgtttcatt gtcctcttga tccgtcgtaa tattgatcga tgtgtcttta
    31021 gcagtgatct ttagcttttt ctgtccttgt tctaacaaag tatttgttat tggctggtag
    31081 tctttttcaa tataagattc accagacgtt tggatagtat agccactgtt ttccatctca
    31141 tgcaaagata aattgccacc gtttaggatg acttttcctt ctttgctgat caaactgtct
    31201 tctagatgga agttgctgtt ttcacctgtg acgatcaagt tatccacatt ggcctcatct
    31261 aatcgaagtg agcctaattc atctttcgca gttattgttc ctcctgtaaa ttcattgaac
    31321 gatacccagc catcatgtgt cttagtattc acttttttga ttgatacttc gttgatatca
    31381 attgcactat tattcccttc gattgtcaat tcagataatt catgatctgc agggacaaca
    31441 atagtgattt gtgcacttgt gtcttctaaa ctaatgattg cacctgttga ttttttgact
    31501 gcattcacag tcaacacgcc atttttctcc tttatttctg gcttttctgt cttatcataa
    31561 gtcgttttta tctcaaaatc caatccgcgt atgaccgaaa ctgtttgatt ttctgcatgg
    31621 atgacgattt tgtttgcatc cttgattttt tttgtctcag taaccatatc gatcaaccga
    31681 ggaccattat cccaagtcag actcttttga gcgcctaatg tataagttgc acctgctagg
    31741 aggccaccag taagcatcag accaataccg gtaatcaaaa aatgtttcaa tctcaattta
    31801 tgtgtcctcc ttcaaacgcc cgctgaatgc agatctcttt ttgtaataaa acgtcgtccc
    31861 atccatttaa caaagttcat catgacataa aaaagccctt ttgttccttt cagcaacagt
    31921 ggcgaaataa atactgcgct tcctgtggcg aacagaccga caccgataaa gaataatcca
    31981 ctcagaatcg attgtccaaa cacactgatt cctgagatga tcatgaatag gccaacacct
    32041 aagatactga tacataaaac atagatacta aaaatgagcg ctagtaaagc aaccaatagt
    32101 cccccaataa ccaatataaa ccccagtgct agtggaatga ggacaggaga agcaaataaa
    32161 ccgataatga ttaaccaaat caggcgaatt tgtctttttg gatttttcac taactcgttt
    32221 tctgcttgtt cttcttctga aaagtaactg atttttaatt ttaaggcaaa ctgctttggt
    32281 gtaccatatt catcaatgat ctgatctaat gtttttccag aatctaaaaa atattcctca
    32341 taatactgga tcaaatcaaa acgatcgtct tcaggaattt cttgaagatg atccacaact
    32401 tcattcaaat attcattcat ttgtgctctc ctccaataac cggtctaaag aatctcgaaa
    32461 aacaatccat tcatcaataa tttcttctaa atgacgactt cccattggtg tcaacgagta
    32521 atatcgacgg tttctgcctt caaaaggttc atcataggtc tcaagatatc cttctttttt
    32581 caatcttctc aaaaccggat atagtgtaga ttcactgaca gagagacttt cttgtacgat
    32641 ttttgttaag gcatacccat acatatcttc cttgcttaat gctgctagca cagtaccatc
    32701 aagaagaaca gttggaatct ggatgtgcat tacgtcacct tctattctca agtgtaatat
    32761 tttatttcaa tctatattat acaacatata atatagtttc aaaatcagtt tgtcaaatac
    32821 aaaaaaactg actaaaagat ttgatccttt ttagtcagca aaaaatggct tctctttgat
    32881 ttttattata acagtggcat aatccaattt gtccacatcc agctcagtgg catgataacg
    32941 atcattgcag gtatcatgtc agctactggg aacattttca cgttgatcat tctaaaaccg
    33001 gtagcgacca tcaagaatcc gccgcaagct ttaaaatcta agatcatgtc tggtgtagtc
    33061 aatggataaa taaattttgc caataagaac aaaatataaa aaataatgaa ttggggaatt
    33121 gctatcacag aaacgacata ccctaaatta cacgcaaaaa tagctgctgt gaaaaaatca
    33181 aggacagatt tagaaatcaa aatcgtactg tctcctgtca tcccagaatc taaacttcca
    33241 tagatccccg taccacttgc acaaaataga acaatgaccg tcactaatgt gctgataaat
    33301 tcatcgtggg tcataccaag cttttcacta gggaagattt tagaaatagg tacttgcatc
    33361 agcgcagccc ccttatttat cccattacct aaatgaacaa tcaaaccaat cgctgttcct
    33421 atcactaaag caaaaataac agccggcata tttttcatcg gcgcaatgga atagattccc
    33481 atccccatcg aacacacacc aaaaaccatc gtcagctgtg ctttaaaatg ttcacttaat
    33541 ttatttccta ctaatccgcc aattagtccg ccaaacaaaa cggaacctac attgatcaaa
    33601 actccagttg gcatcaaaaa actcctctct ttttctacga agcgaaaaaa atcagaaaaa
    33661 tttctgtaat tattgctttc gctgcaagaa agattgtaac agacagagaa gattacacca
    33721 attcattttt tgtgttaaag tattctttat tggaataagt aggaggaata tgatggatat
    33781 ccataaattc gaagtttttc ttgatttagc cgaaacaatg aatttcacca aaactgctga
    33841 tcgacaattc accacccaag gaaatatttc taaacagatt ctttcgttag aaacagaatt
    33901 agacgtcaaa ttattcgaac gcgcccatag aaaaatcgaa ttgaccgaag ctggaagctt
    33961 attgctccca tatgtaaaaa atgtcgtaga acaataccat gctatgcaag aagtgcttga
    34021 aacctatacg aaagacaaca atctttcatt aaatatctta acgataccga caatgatcaa
    34081 ttataaaggt ttttccaaaa tcaccgagtt tttgaaacgc catcctgaat ttacagtcca
    34141 gttgaaagaa gtggaaagtg tcgaattaac ttacaatgac gccaatgaac atagtgacac
    34201 gatccacttt gctagaagtt tccaggcccc accaagttcg attgagtggt tgcctactga
    34261 aacagacgat tttgtagcag ttctacctaa aaatcatcct ttagctagta aaaagaaatt
    34321 ggatctaagc gaactgaaaa aggagaactt tttgctcctt ggccccacta cgaacttgta
    34381 tcaacctgta ctagatctgt gtcgcgaagc tggatttgaa ccaaaaatct cttataaagg
    34441 agcaagaatc gacttgatca tcaatatgat tgcaaatgac atggggattg ctattgttat
    34501 ggaaaaaaca gtcaagaatc tattaaaaga aaatactgtg attctcccta tttctccaac
    34561 aacagagagt tatcttgcat ttactcgtaa agtcggtgag cattctttgg cttcagatac
    34621 attttgggag tatttaaatc aagaagaaaa ctaagcccta cattttctgt ccatctatcc
    34681 acccaaaaaa agagagcgac gcatgacttt cgctctcttt cttgcatcat gtccttgttt
    34741 caatgacacc tctaacattt ctcgtagttc aataagaaag cagcgatttt tatgccaaaa
    34801 gaaccgtaag aacatttccc taatcacaaa aaaacgacta aaaaccccta aaaaccttca
    34861 atagaatttt taggggtttt attctttttc ctattgttta cttaaccgta tcattgctgt
    34921 cgttcctact ccttcgatac tgctataatc aatacgtcca tcatgcagtt ctagaatttt
    34981 tttaaccagt gaaagtccta gcccattccc agaaatttga cgacttgtat ctccttgata
    35041 aaatttttca aacattcgat ctctggtctc ttcattcatt cctacacctg aatcggtcac
    35101 ttccagtaca atctctgtgg ctgtctcaaa tagtttgata tgaatctgtc cattgatttg
    35161 attgtacttt atggcgttat ccatgatatt cagccacact tggtacaaaa actcttcatt
    35221 gcctgtgtaa tttactgcag caagttcgat atccaattct agctgttctt tctcccattt
    35281 aggctgaaaa aaaacgatta cttctctgat ttgttcatct aatcgatact ctttcttttc
    35341 cagttggata cgctggtttt ccagtttgtt caattttaag atgttctctg ttaattgtga
    35401 aagctgcgtg atactttcga taatccgata taaaaatatt tggcgttctt cgtcagagag
    35461 atttggggct tgtaacaatt gaacatatcc ttggattgtt gctagtggtg ttttgaattc
    35521 atgggataca ctggacacaa agtcattcct cagtgtctcg atactattga gttcttggac
    35581 cataacgttg aaatctttat acagttgctg tacttctgct actttctgct gttcatccat
    35641 tcgaatcgaa aaatctcccg ttgctaccag actcatattt gtccctagcg cactgattgg
    35701 atgcaggata cgccgcccaa caaaaatcga tattcctgta cccacgacca tactgaaccc
    35761 cgcaaagacg aataacgggt ataacgttgg ttttccagcc gattcagcag gcgagataga
    35821 atgtcgagac aataagaaaa taaaaccgag aaaacacagc agtgtcacta agatcgaaat
    35881 gaagacaata ctagcaaaat agatccataa ttgtgaaaat agcttttttt tcatctttaa
    35941 ataaccgcct tatagcctag tccccgtact gtgatgattt gaaaatcttc cgtcttttca
    36001 aaacgggtcc ttaaacgttt gatatgtaca tcgatcgttc gttcttctgt attcgtatct
    36061 aatccccaaa tatcatccat caactgttgg cgagtgaaga tcttgttggg ataagacagt
    36121 aatttataca gaagcagaaa ttctttttga ggcagaatca acgaatgctg atcttgtaac
    36181 actgtataag catctagctc taattttgtt tgtccgatta tcaagctact gctgtaattg
    36241 atctttgaac gtcgaagcaa tgcttccaca cgtaggatca tctcattgac atcgatgggt
    36301 tttgtcatat aatcatctgc tcctaatttg aacccgcgtt tcttatcctc aaaatcggcc
    36361 tttgccgtaa tcattagaac aggtgtgtca aatctggtgc tacgtaatga gtctagcaag
    36421 tcatagccat ccattttcgg catcatgata tctgtaatga ttaattctat acgtgtcgct
    36481 tctagttttt tcagcgcatc ctctccattc aatgcggtga tgactgaaaa gcccgctcgt
    36541 tccaacacag aacggtaaag caactgtaat tgcggatcat cttctactac taaaatacga
    36601 ttcattgatc tccctctgtt ttttgaaaaa tttctagatt ttttcttgta gttcatcttc
    36661 agttaacatt tatttcgtat actacgatca ttgttctgat atacttatta gtataccgaa
    36721 tatttcaata cgggagaagg gtgattatgc ttcaattaaa agatataaaa aaatattata
    36781 aagtcggcga aaccaccacc aaagcattgg atggtgtgtc tgtcgctttc agacaaaaag
    36841 aattcgtagc gattttaggt cctagtggtt ctggtaaaac gactatgctg aatgtgattg
    36901 gtggactaga taattatgat tccggtgata tggtaatcaa cggaaagtct actaaagact
    36961 ttaaggacag tgactgggat gcctaccgaa acaactctat cggtttcatt tttcaaagtt
    37021 acaacttgat tggtcatcta ggcattattg aaaacgttga acttgggatg acattaagtg
    37081 gtgtttctaa agacgaaaaa cgaaaacggg cagaagatgc attgcaccga gtcggcttga
    37141 caaatcatat gcataaaaag ccaaatcagt tatctggtgg acaaatgcag cgagtggcca
    37201 tcgctcgagc actagccaat gacccagata tccttttgtg cgatgaacca accggagcgt
    37261 tagatacaga aacaagtatc cagatcatgg aattgatcca agagttatcg aaagaaaaat
    37321 tagtgatcat ggtcacacat aatcctgaac tggcccatca atacgcagat cgaatcattg
    37381 aattttctga tggtaagatc ttaacagatt cccatcctca catcgaacga ccaaaagatg
    37441 atcaatttaa cttacgcaga acaaagatga gtttttggac agcgttaaag ctttccttca
    37501 acaatatccg aacaaaaaaa ggacgtactt tcttgacctc ctttgcttcc agtattggga
    37561 tcatcggaat cgcgatcgtt ctgtcccttt cttctggatt ccaaaaacaa atcgataaca
    37621 cgcaagctga aacgatggcg aaatttccga ttactatttc taaggtaacg actaaccaga
    37681 ctcgtgacga tgccggattg ggtgcaagca aagcggatta tccagacagc aaaacgatta
    37741 ctgcaaaagt cagcgaagaa gataaagcac agcacacgaa taagattgat caaacatacg
    37801 tcgattacgt aacagacatc gatcctaact taagtaataa tatcggattt acccgtacta
    37861 caggaatcaa tcttttacgt gatgtaaatg gcaaagtaca gcctgtcagc ttctcgaatc
    37921 aaaatcctga tacggaatct ctttctttat ctagtacgat gtcagcaatg acaggtgtgg
    37981 gagtgtcaag tttccctaca cagcttgaca ctagcaaaga aaacttttta aaagacaatt
    38041 attctttact tgccggaagt tatccagcct cagcaacaga tgtcgtgctg atcgtagacg
    38101 gcaataataa tactaatatc aacgcattga agaatcttgg atttgatgtg aaagaagacg
    38161 aaaaacttga ttttgatgat atcgttggta caacattcaa attagtaaac aacaatactt
    38221 actatacaaa acttccaact gggaatttta tccctaatac agattatgat gcgatgtatc
    38281 agaatgcttc tgatgaattg aagatctcgg ggatcctacg cgtgaaatct tcttctacaa
    38341 tgaatctctt atctccagga atcgcttata gcgatcaatt aacgactcaa atcgtcaacg
    38401 aaaacaaaga atcagaaatc gtcaaagctc aaagagacag tggtgtaaat gtcttaacta
    38461 ctgaaaaagt tgacgaaaat gccaaacaaa cattgcttag ttatttaggt ggagacagct
    38521 tgccttcaag tatcatgatt tatccgaaca attttgaaga caaagaaaag atcttggatt
    38581 atctagatga ttacaataaa ggcaaatcag atgaagataa aatcatttat actgatttag
    38641 ctggaacgat gactgaactg actggcggat tgatggatgc tatcacttat gtccttattg
    38701 cttttgcagg gatctcttta gtaacaagta tgatcatgat cagtatcatt acttatacat
    38761 ctgtgattga acggacaaaa gaaatcggtg tactaaaagc tttaggtgca cgtaaaaaag
    38821 acatcactcg cgtatttgac gcagaaacgt gtattttagg tatttcttct gggatattag
    38881 gtgtgtttat tgcatggcta gctacgttcc ctatcaatag catcttatac aacatgacgg
    38941 atctaaaaaa tgttgctcaa ctaaatcctg tccatgcgat tattctagtg atcgtctcta
    39001 ctatattgac gatgcttggc ggtcatcttc ctgcacgaat ggcagcgaaa aaagacgccg
    39061 ctatcgcttt gcgtgcagaa taaggttgtg acaaccacat ttagatttga gtcataagag
    39121 cgctgaaata gtagaaaaca gcaagaaacg aggaagtaat atgttccttg tttcgcgctg
    39181 ttttttttaa ttatttttta taattctggt atacttttct ttcctttgta ccacaactct
    39241 tctggcgtat acctgtcttt tccatttatg aatactgttc catctgcttc aatcgttact
    39301 tcagtcccaa tccacatatt acgagaaagt gcgagaagat tttttctttt tcctcttcct
    39361 ttttttccaa attgcaaggc atcggttatc tcttctgtcc aatgagattt cacgtatttt
    39421 acttctccgt tttcaaatgt aactttcaaa atattcgcta tattttccac ttttactgct
    39481 ttaggaaatg actcctccat ttttttcact ttccttcctc caacactaag tatgcgcttt
    39541 cttttagtga taagtatatc atagtttatt ctattatcaa aaaaacgcat ccattccatt
    39601 gtagaatact ttaccgaaca agttgaattg ttttcctctt tttcaccttt tactatagat
    39661 aggtaaagac aactaaggag gaatctctca tgacagatca accgtatgat ttaagaaaag
    39721 tcatcgaaga actaaaaaca cttccaggtc aatatcacga aacagatatt gaaatcgatc
    39781 ctgaagcaga attatctggt gtttaccgtt atatcggtgc tggcggtaca gtaaaacgtc
    39841 cgactcaaga aggaccagct atgactttca acaatatcaa aggtttcccc ggcacacgtg
    39901 tgaacatcgg aacaatggct agtcgtaaac gtgtaggtga aattttgcac catgattatc
    39961 gaacacttgg tcgtttcttg aaagacgctg tagaaaatcc aatcaaacct gtgaaagtag
    40021 acaaagcaga cgctccagca caagaagtcg ttcatctagc taccgatgca gacttcgata
    40081 ttcgcaacat tttgcctgca cctacaaata ctcctgaaga tgctggtcca tacatcacaa
    40141 tgggtgtagt cttaggatca gatccagaaa aaacaatgag cgatgtaacg atccatcgta
    40201 tggttctaga agataaagat acgatcggta tgtacatcat gcctggcgga cgccacattg
    40261 gtcacttcca aaaacaattc gaagccttga ataaaccaat gcctatcact atcaatattg
    40321 gtttagatcc agcaattgcc attggcacga ctttcgaacc acctaccact ccacttggct
    40381 acaatgaact atggtgtgca ggagctttgc gtaacgaacc tattcaaatc gttgatggta
    40441 tagcagtcga tgaagtgggt attgctcgtg ctgaattcat cattgaagca gaaatcatgc
    40501 caaatgaaac aatgcaagaa gatatcaaca cgaactcagg aaaagcaatg ccagaatttc
    40561 ctggctatac tggggatgct aatccagctg tacaagtagt gaaagtcaaa gcagttactc
    40621 accgaaaaga caatccaatc atgcaaacaa cgattggtcc cagtgaagaa cacgtatcta
    40681 tggccggtat tcctacagaa gcaagtattc ttgccttggt cgataaagct attccaggaa
    40741 aagtagtaaa tgtctacaat cctcctgcag gtggtggtaa attgatgacc atcatgcaaa
    40801 tccgtaaaga aaacgaagcg gatgaaggta ttcagcgtca agcagctatt cttgctttat
    40861 cagccttcaa agaattgaag acagtcattt tagtcgatga agatgttgat attttcgaca
    40921 tgaacgatgt agtttggact ttcaacactc gtttccaagg agataaagat atcatcgtga
    40981 tcccaggaat gaggaaccat ccattggacc catcagaatt accagaatat aatcctggct
    41041 ctattcgttt ccgtgggata agtgcaaaaa ctatctttga cggtacagtt cctttcgata
    41101 tgaaagaaca ttttgtacgt gcaaaattcc aagaagtaga agattgggaa aaatatttga
    41161 aataatgaat gatctgcaac tgttttgaca tcataaaaag gagtgcggaa aatggaacaa
    41221 ttggcacaac ggaagaaaaa aatcgtgatt ggtgtaagtg gcgcttcagg caccatttat
    41281 gccatcaacc tagtgaagaa actaaaagaa tatccgatga tagaaacaca cggaatcatc
    41341 agtccatggg caaaacagaa cttaaagctg gaatccgact tatcactaac tgaattcgaa
    41401 agcctgtttg attaccatta ttcaaacaaa gatttaggtg ctgctgtcgc cagcggatca
    41461 tttttgaccg atggaatgat catcgtaccg gcaagtatga aaacagtcgc aggtatctct
    41521 gttggtttag gcgacaacct gattgcacgt gctgctgatg taacaatgaa ggagcaacga
    41581 aagttagtca ttgttcctcg tgaaacgcca ttaaatgcca ttcacttgga aaacttgact
    41641 aaattagcac gactaggtgt gcaaatcata ccaccaattc ctgcttttta taatcagcct
    41701 caaacgatcc aagatcttgt taatcaccat acaatgaaac ttttggatca atttgaaatt
    41761 gtaaatgagc attcaaaacg ttggcagggt gattaatatg gaaaaagaaa cgatagttga
    41821 agtaaccaaa ctaggtttca cgatccaagc tgctgttaaa gtaatcggta aagacttatt
    41881 gatcacttta acaggcggag atacaccaca tatcggaaca gtcactacat tttctcgtga
    41941 tacagagatg caaactgtac gtttccctag ccacgatggt cggttccata aagacgatgt
    42001 cttagccgaa aaaatagctg tgatcatcaa aactgccgtt ccgggaagtt gtacgatcac
    42061 ttccggtatc catgttgacc atatctccaa tgcacaaatc aacgcctctt ttccgatgtc
    42121 agaagagtta ggttacaaga ttttagattg gttggaaaaa atagatttcc atatcaaaga
    42181 accagtttat tataaagatg gtgaaaaacc attatgaaag aagaggttgt gaaatcagcg
    42241 ttatgacctg agtatgagag aaaaaaatgg aaaaatagct tctcatattt tgccgttttt
    42301 gagctaatac cgagggacag ctgattgaac gccgtttatc aagaggttgt gataaagccg
    42361 cttcgtttcg agtagtaaga aaaattttgt aaacatgggt ttccacattt ttgcataaat
    42421 ttgacttact accgagaaac tggcttttga acaccgttta tcaagaggtt gtgacacgtc
    42481 ttttgtcaca acctctttta tttttgcttc actgtaactg ctacaatatc accgatttct
    42541 tttccgatgt ttttacgaat atcttttcgt agtccaagga tgtagcagac tgaaccatct
    42601 ggatttttca cgcccatatt cacgatactg ccttcatacg gcacattgtc aaaagttgct
    42661 tggactttaa ctcttccagc accgaattct tttcttatat catacggaaa aataatatat
    42721 gccccgccct tgccgacttc ggaagcatag atttttgatt caaaagaata aatttccctc
    42781 attttatttc tcctattttt tacatctagt atagcatagc aaaaaaaaga aggaactgtg
    42841 acaaaagtct tgtcgcagtt ccttttttcg aataaacggt gttctcctgc caactcctcg
    42901 gtcacaagtc acaatagtca acaaacatga gaagctgttt tttgaaattg ctccttgtga
    42961 ctcagagtta aacggcaggc tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc
    43021 tacggcacta agcccaatca gatgaaaaat atggagtgct atttttatct gattgttctt
    43081 actgcttgat gcagagcagc tttttcacaa cctcctacat ggtgttcaaa atattattcg
    43141 ccttttgctt ctttcactaa ttttgcgaat gcttgttgtt ggaattcagc agctaaggct
    43201 ttcgtacgtt gttcttgctc tgctttgctc atttttggat tttcagtcat tgcttttacc
    43261 ataccgtctt gaacataagc ttttgcttca ctttccatcg tactttgctg tttcttcact
    43321 aattcagcta acttggctgc ttggtccgta cttaattcta cccatgtctc tgggattttg
    43381 aatgtattca ctcggctgtc atattcgtga ttgttatcag caatattgaa ccagaattta
    43441 tacatgtcgt ttttgtattc ccaataagta gttttcgtca ctttttcagc atcgccgtct
    43501 gtcttttcta ctttatttgt ttcgttatcc gtaccagttg cttttggttt ttcttgtttt
    43561 tcatttgttc ggtaaagata cactttttct tttccattcc ctaaagcttt atacaaaagc
    43621 atatctgctc cttgggaatc agcactggaa acaatttttt ctgtttttgt ttccgttact
    43681 ttttccattc caaagtgatt ggacaaatta gcgacgatca aacttagtga agcgacgaag
    43741 attagtccga aaatcaaaga taaaaaggtt tgccatgttt ttttagcgaa cacgttcgtt
    43801 aaagcaaaag caagcaagct gacaatcaaa actccaataa tcatgcatta tcccccgctt
    43861 tcattagaac aggttctttt ttcttcaata aaaaggcaat aataaagcca agaatcccaa
    43921 agatgatcgc tacgataaac gcggcatggt aacctgacag tgtggcattg attgcctgat
    43981 ctttataagc taatggcgta ttatccaata cagatttgct tgggatattt gcttttgtca
    44041 cattcgtcaa cacactgatc aaaatagctg taccaatcga gcttgcgatt tgacggaatg
    44101 tattatttac cgctgtccca tgactgatca agttatttgg caatgcattc ataccagaag
    44161 tcgttaccgg catcatgacc atggagatcc caaacatacg gatcgcataa aggatcacga
    44221 tatataaaac tggagtcgtt tttgtcaaga aagcaaatgg tgcagttgcc gctgtcaaaa
    44281 tgaacatccc tgtgatggct aaacgtttcg cgccgtattt atcgaaaatc gcacccgtca
    44341 caggcatcat agcccccatg atcaatgcac ccggcaacaa catcaagcca gaatggaatg
    44401 ctgattctcc acgaatattt tgaatataca atggtacgac catttctgcc cctaccatcg
    44461 ccatatttgt tacaccagct aaaacagctg caatcgtgaa tgtagatgat ttgaatacac
    44521 gaagttccaa gaatggatgt tccaaatgta attgacgcca tgagaacaag gcgatgaaaa
    44581 tcacaccaac aactaagaaa ccaattactt tcaagcttcc ccagccgtca tctcctacac
    44641 tagaaaatcc gtaaagtaaa ctaccgaatc caatcgttga taaaatagcg gataaaatat
    44701 caatgctagg atttgacaat ggaataacac ttttcattag gaagaatgct aaaaccaaga
    44761 caagaacaac gattggcagt accataccaa acaagtcacg ccaatggtag ttatcaatga
    44821 tataaccaga taatgtaggg cctaaagcag gagcaagtcc aataacgatc cctgacatcc
    44881 ccattgctga tcctcttttt tctggcggga aaatagatag catgatattt tgcaataatg
    44941 gcatcgatac tcccacaccg caagcttgga tcaaacgacc gattagtaat gtactaaaat
    45001 taggtgctgt aaagcaagta atcgttccga tcaaaaagat cgtcatggca gaaagatata
    45061 aatttcttga actgaattta ttgatcagcc atgctgttat tgggatcatg atcccgttga
    45121 ctagcaagaa accagtcgtt aaccattgca catcagacgc tgaaatatcg aaagctttca
    45181 tcaatgtagg aaaagctgtc gtcaataagg tctgattcaa aacggtacaa aatgtaccaa
    45241 ttaataagac aacaactaaa agtgtccgat tatatggttt tccgtaaata tctacgggtt
    45301 ggttgttact catatttctc cttctttctg aattttttct gaaactacta gaatacttta
    45361 gtcctaaatt cgctatttgt caacctactt gacacataag ttaatacgga tataattaag
    45421 ggaagcaaga ggacaaaagg agtgacaaaa atggttgggg cttcccttaa acgtttgttg
    45481 gaaaatgatc aattggttgt tggcatcagt gaattaagtg atatcgtagg tgtgtctcca
    45541 cgtcaattaa ggtattggga acaaaaggga ttcattcgtt cgatcgaagc tgatgcgaat
    45601 tgtcctagaa aatatcgttt acctacagtc ataaaagtag aactgatcaa aaaatattta
    45661 gatgacggat ttactttgtc aaaagctgca gaaaaggcag aaatccgcca aaagaaaatg
    45721 caccatgtcc gtaaagtttt ttcaaaagca atcaaagata tcgaattgat cgacgaacgc
    45781 tatacgattt tacaaatcgg taacttcaaa gaagagaatg ctaagatgta catcattcat
    45841 gacaacgaga cagacgaatt aacttacaag ctccttcctg tcgatgaaaa agctgactac
    45901 gaacagttgt taaaagaact ctaaacgcca ctaatctcct aagtaccaag ctttttaata
    45961 agtagatgct acataaatac ttgaaaaaag gcctgtttga acataagaat atccgaacgg
    46021 tgatctgcgt ttctttcata tagaaaggaa ttctccatca ctgttcggat atttttttat
    46081 ttttttcggt tactttcttc taatacatct gttagccaat ttgcatattc tgtttcccga
    46141 ttgatcgcat gcgctaaaat caggtagtgt ccgtaatttt catgtttttc tttttcagta
    46201 ggaaagatcg ttttttttcg ctctaataga tgaagtcgtt tttcttcatg aaggtcacgc
    46261 tgctgctgaa taatttctac taatgccgga tcattcacgt ctttgacgaa atacaatttc
    46321 agaacaaatt cgtctcgatt aaccggtagt tcattggtgg gtgtatgaat ccactctgcc
    46381 aattgttcct tcccttcttc tgttaattca taaactttct tttccaattt ttcacctgtg
    46441 atctctactt gatgctgaat gattccttgc tcttccattt ttgcaagttc aggataaatc
    46501 tgactatgtt ttgcttgcca aaattctcct atttcatttt tgaacgattg attcaattca
    46561 tatcctgtca tcttcttctt acttaataac cctaacaaaa tatatcgaag tgtatttttt
    46621 cttgccatca gttttccctc cttgacaaat ctttaaatcc attctatcat aaatgagtaa
    46681 tcgaaaacat gtagtttatt acatgtttta atttataagg agatgcttaa acatgaaaga
    46741 atttaaagaa ttggaagatt ttattggaac tcactttatc tatacgtatg acaatggttg
    46801 ggaatatgaa tggtatgcca aaaatgacca tactgttgat taccgtatcc atggcggaat
    46861 ggtcaaaggc cgttgggtaa aagaccaaga agctgatatc gttaaattga cggacggcgt
    46921 attcaaaatc acttggacag agccaacagg gacagacgtg gcattggact ttatgccaaa
    46981 tgaaaagaaa cttcacggaa tgatcttttt ccctaaatgg gttgaagaac atccagaaat
    47041 cactgttact ttccaaaacg aacatatcgc agaaatggaa gcagctcgtg aaaaatatga
    47101 aacttatcca aaattacttg ttcctgaatt tgctacgatc acttatatgg gtgatgcagg
    47161 tatagacaat gaagatgtta ttagcgaaga accatacgat ggaatgccag atgatatccg
    47221 tagcggaaaa tacttcgatg aaaattataa acgagtaaaa taaggttgtg aaagagaggt
    47281 tgtgaaatca gcgttctgac ctgagtatta gagaaagaaa cggaaaaata gttcctcatg
    47341 ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tatcaagagg
    47401 ttgtgaaatc agcgttatgc tttgagtaat aagaacgcta gttagaaaat agcttttcat
    47461 attttctagg ctagtgggct tattaccgag aagcagccgt ttgaacaccg tttatcaaga
    47521 ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac aaatggaaaa atagttcctc
    47581 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttatcaaa
    47641 gattgtaaca actgcatatt cacacagtta aattagtgac ttcaaaatga aataatgctc
    47701 ccagcaaaaa attaggctgg gagcattatt tcgttattct gttcatcaaa aatcagcgtt
    47761 ttgattccat ttcatcacaa gttcctcctc atttactgct tcatcttttt gctgtgtttg
    47821 aattgtaaaa ccttgtgaaa gatagaaatg aatagctgat tgattttttt gatagactgt
    47881 caaagtcagt gttttattgg tttcttttat ttttttcatt agttgcgtac cgattctttg
    47941 ttgccggtat tcccttttca caaagattcc tgcgataaac tgatcaatca ccccagcaaa
    48001 accaataatt tcttgatcta tttctgctaa gtaaatcact gcatctggta aagctttcct
    48061 aacagattct acttgattct cccaataagt tgatggaatg aattcatgag aatccaagtt
    48121 agcatgcagc caaatcgata gaacagattc cagttctttg gcagacaatt ttgttgttgt
    48181 gcggatcatt ttttctctcc ttacttattc attgatttta aaataaaaac catttttttg
    48241 aagctctttt acaagttttc gcccctcaaa aaagtatatc ttctcttgtt ttacttttct
    48301 aataccaaaa gaaacagcaa ctttaggatc atcagctgaa acgattcgat aagttccacc
    48361 aggcaattga tccagcttga ctttcccatg atggtcgctt tgtactgaaa acggcacacc
    48421 atttctagta agtgtttttt tcttatgttt caaaatgaat gaactaccat ttaccggttt
    48481 ccctgacgaa tcactaataa taaatgaaaa atcaagcact tttttactta atctatactg
    48541 atagattagt cgtccgataa acactaacag tatgactaca gctattatcg ttcctgcaag
    48601 aataaaccat tgccgcatgg ttctttcctg atttcctttt ccttcttctt tttttaccga
    48661 ttcgttataa ggaatccgat gtcctgtcac tagcaaacga tgcgtgttga tcatatacgg
    48721 cgtacatgta agcaaggtaa ctaagtcttc tccttctgaa atcgttagaa cagacgtgtc
    48781 atctggcagt accacttgta tatttttaac ttgataagcc aatttctccc ccaaaacagt
    48841 caaaataaac gtgtctccgt tttctaaacg atctaattcg gtaaataacc gtcgattagg
    48901 taaaccgctg tgagcagaga tcactgaatg cgtcgaattt ccaccaagcg ggaaagaggt
    48961 tccttgcaag acgcctgctc cattttcaag gatcctacca ttgagccgat cataaagtga
    49021 aatatttaat tggatcttag gtatattgat acttccgatc agccattcct ctaattggct
    49081 ggatgttgta ctttcatttc tgttcttttc attgaaagga tcagtaccag gattgaatcc
    49141 ttggtcagtt aatcgttggt ttttctcctc cattttcttt cgctgcactt caatttcagc
    49201 tgcggtccgt ttttgtactt gttcgatacg tttttgatca ataaaactat ttaaagaatc
    49261 cacataaaat ggatataaag cgatcagtaa ccctacgacg atacatatta ataaaaacaa
    49321 acgaaacaaa agtcgacgag actgtttttg cttactctgc ttcacatgtg tcctcccttg
    49381 caagtttttt tgttctttct tttattatat gggttcagga aaaaaataga aaatgaaagc
    49441 cgatgaggtt gtgaaaaagc tgtcctgcat caagtaataa gtacagccca aaaaaatagc
    49501 tactcatatt ttttgttggg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    49561 taaggaagag gttgtgaaaa ctgcgttatg ctttgagtaa taagagcgct agtcagaaaa
    49621 tagcttctca tattttctag gctagtgagc ttattaccga gaagcagctg attgaacacc
    49681 gtttaccgag aggtcatgaa aaagctactt tgtttcgagt attaagaaaa attctgtttc
    49741 aaaacaagga gatgcaacaa aacttatgtc gcatcctctc tccttagaac tttcacttat
    49801 gtttttcttg taaaattcat aaatattttc atgaattttc taatttcttg cctacctctc
    49861 gcataggata tatgatgaat ttatctaaag tttgcaaagg agttcgacaa ttgaaaaaat
    49921 atggcccatt tttagcaatt tttttcattg ctttggcatt tctcatgcct catttattca
    49981 cacataaact aattttgggt gctgatgccc cattccatta caatcggttc tatgatgccg
    50041 cgcaacaaat taaatatggg gatttccatt attttccttc cctttatgga ttccagcaaa
    50101 gtggcaggat cgtgaatgcc gtttacggcc catttttcgc ttatttacaa ggattgatcg
    50161 tgttgcttgc aggtagctgg tttcattatc agattctttc aaatttcatt ctttatctta
    50221 tttcaggatt ttctatgctg attttactga gatatgtcaa tgttcgaaat tgggtaagtg
    50281 taccagtagc cgttttattc atgagtacgt attctattca atactggtct atcaaccaag
    50341 gattcactag ctgggggact tgtttttatc ctttatgtat gatccctatt gctgatttcg
    50401 tccttcataa aaagttccct gttatcaaag tcgctgtctc agtgggactt atgacacaga
    50461 tccatttact gtcttcgatc atgttagctt tgatgtatat ccctttttat ctttattact
    50521 tttttaacca gactgaaaaa ggaaaagcac tgcttcaact gattaagtcg gtcttgcttt
    50581 attttgttct gacagcaaat atttgggcag gattagctat tgtttacagt gggaataaga
    50641 ttcttcctcc ctttgttaac agagaaatga gtcaaaaggc gatagatctg gatggcagtt
    50701 attggctcca ttaccctaag gcctttccta tattgatatt atcaggtttt ttgcttttta
    50761 ttttctttca acaaaagaac accttattcc aaaaaatcgt gttgtacaca agtcttgttt
    50821 tcttttttct ttctactagc ttgattccat ggacgacatt gatcgaaaaa aatgtgcctt
    50881 ttattagttt gatccagttt ccatttcgat ttttcgtgcc atttacgcta ttgcttctac
    50941 tttaccttgc cctttcactg aaccagtggt ctgaacaaaa gtggttccgt cttttaagta
    51001 tatttggcat tcttattttt tcagcacaga cgatccagaa cttataccag catctggaaa
    51061 agtgggaaaa tgaaacattt gtcagtcgac atacttatct attcgatacg ccggaagaag
    51121 caaggaaaac attcttcagc aaagatatgt ctaccagctt gttcgttttc caaaaaacca
    51181 cacctgacta tctgccaatc tataaggaga caaaagacaa taaatacgac cggtataacg
    51241 aagaaatact agaaaacgaa acaactttta taaaaacaca tccaggcggt cttttgacaa
    51301 tcaagtggaa aaacactggg gacaaaactg ttcatatccc tgttatcgtc tacgatcgga
    51361 ctgtgctaca gcaaaatgga aaaacattga ctgattatga agtaacagat atcgggaccc
    51421 caatcgtgaa gcagcaaaaa ggaatcaacg agctcacgct tcattatcaa acgccaatct
    51481 atttctattt cattctttct cttactttga ttggctggtt taccttgcta tgtttattta
    51541 tttatcatag atacaagctt ttacgtgctt aggcaaaagg gataaataca tccgatcaaa
    51601 aaactctcca aacggtataa tcgtttggag agttttattt taatcagttt ttttatgtta
    51661 tatgttatat tttttattcg ttcacatcta attcgatttc caccccgtag tgatcactga
    51721 tgattggact atcgatccca tcaaaaatcc gttgatattt tttaacctgc attccttcag
    51781 ggacgaaaat aaaatctata cgcaattttt ctgtattttg ttcccaacca tctattttct
    51841 tttccacagt agctgctttt cctttttcat tcgcgacaac atacgaatct tgaagaagaa
    51901 ggcaactttc tcttacagta taataacctt gagagtctac tggattattg aaatcaccta
    51961 ggaaaaaaag tggtacgcga gtttccaaaa agtagttttc caagtttttc cactcaaaat
    52021 aaaagccact ttttttatct gtccaccaag aaaagtggca gctcgagaca aaaatgtcct
    52081 gatcatctat ctttgttttc ccaatcaaga tcttgcgtgt ctgataatct tctttctttt
    52141 gaaattggga gacggtaagg acctgacttt ccaatgtttt tttcgtaagc agtgcatttc
    52201 cttcttcata tttatcataa ccgatgtggc tcatttccca actccaaaaa tactcttttc
    52261 cgtgttcctt taaaagctga actaaacggt aggcaaaatt atctttacgg ataggtactt
    52321 gattctttac cggacagaac ttcattagct tcgcaggttc tacttcttca gattccagta
    52381 attggttgat ttcttgtaaa gcaatcactt cataatcttc taacaggatc ttatctgcta
    52441 attcttgcaa ttttttctct ggttctggct caagccagct atgcgtgttg agtgtcatga
    52501 atttcattgg ttttctcctt gtcttcattt cgaaacaaaa gggttgtgac aaaatttttg
    52561 tcacaacctc tccagcaaat agtgttctcc tgctaactcc tcagtaataa gctcaatgga
    52621 ccaggagcta ttttttgttt ggctgttttt atcacttggt gcagggcagc tttttcacga
    52681 cctctccact aaacagtatt caaactgctg cttctcggta ataagcccaa ccaaacgaaa
    52741 aataggagga gctatttttg tttggctgtt cttatgactt gatgcaggac agctttttca
    52801 caacctctcc ttacatttta atggagccga tcactttacc agctgtcact gtacctaatt
    52861 gcttgatcac tacttcttct actttatcgt ttgtaaatac gatcatgatc gttggatctt
    52921 tttcttcgtt ttggatcaca tcaagatcca tctcagctaa tttcgttcct gttcctactt
    52981 cttggccttc tttgacagca atctcaaaag ctggctgatt catttggact gtatcgattc
    53041 ccatatggat caaaacttcg ataccatctt tcgtttccag cccaattgca tgtttgctag
    53101 ggaaaatact tgtcactttt ccagcgatcg gcgcaacaac ttctcttgat gttggaataa
    53161 cagcaaagcc gtcacccatc attttttgtg agaataccgg atcttttact tcagataaag
    53221 gaatcacttc tccagaagct gcggaaacta gttcttgttc tatacctaag tattgcttac
    53281 tacctgcttg tccatttcct gtagaaacca tttctggctc tggaatctct gctcctgatt
    53341 gcagcagatc ttcgatatct gatttcaaga catctgcttt tggtccataa actgcttgga
    53401 ctccattgtc tttgacgatc aatcccatcg cccctgctcg tttccaggct tcttcagtcc
    53461 ctactttttc tcgatcattt acacttacgc gtaaccgagt catacaagca tcgacatctt
    53521 tgatattttc ttttcctccc agcaaatgaa tgatctggac cacttgctga tctgctgttc
    53581 ctgttccgct gttagataca acggtttctt cactgtcatt gtcgtaattt ccgttacgtc
    53641 ccggtgtagc aaagttgaat tttttgatca agaaatttgc taagaaatac gtaacaacac
    53701 caaaagcgat cacacacaac acgaagttga taagatctcc acctagaccc gctttgatag
    53761 ctaacggtgt ccgagtcagc aattcgatat tcccaaatga atggacccgc aatggcaaga
    53821 tatctgccat cgcaaatgca gccccttgga tcactgaata aatgacatat aatggcacag
    53881 cagcaaacat aaacatgaac tccaatggtt ctgttacacc tgttagaaag acagccaacg
    53941 ctgctgaaaa atacattgat ttatatcttg ctttcttatc aggatcgaca ttacgataca
    54001 tcgcaaaagc cattcccatc aagatacctg aagaaccaat catttgtcct actttgaaac
    54061 gagccggcgt ccagttatgc aacacaaact catattgcga catatcccct gcacctttaa
    54121 gattcactaa atcagtggcc caagccaacc ataacggatc ttgcccaaat acttgtgtcc
    54181 ccgcctgtgc gcctgataaa atctcatacg atccgccaag ctgtgtatag ttgataggaa
    54241 tcgtcagcat atgatgcaat ccaaatggca atagtaaacg ttctaatgtt ccaaataaaa
    54301 acggtgctag aatcggtgcg ctttcttgtg attctgcaat ccataaacca aaattattga
    54361 ttccagcctg tacgtttggc cacaccacag caagaatcaa tgccacgatt gttgaccata
    54421 agataacaac aaacggaaca aagcgctttc cattgaaaaa tgacaaagca tccggcaatt
    54481 ttctataatt atagtactta ttataagcca ttgccccgac aaatccagcg atgatcccta
    54541 cgaatactcc catattcaaa gctggtgctt ccaatacact tgtaaaaaat cctttaacca
    54601 tgatcttcgt accgaacaga gtgtgggtaa atgcatcttc attcgcaagc atgtcacttg
    54661 tgacaccaaa gatagcccca gtgatccgat tgattaaaat aaatgagatc ccagctgcaa
    54721 atgctccgcc tgctctttct tttgcccaac ttcctcctat tgctaaagca aataaaatat
    54781 gaagattacc aataattgcc caaccaatat tttcaattac tccgcccgtt gtgacaagcg
    54841 gcgtccaatc aggattgatc aagggaattg atttccctat actgatcatc aacccagctg
    54901 ccggcataac tgctaccaca accattaaag cctttccaaa tttttgccaa aactcaaaac
    54961 taaatatctt tttcattccg tttagctcct ttacgcaatc ggtttcgtta aacgtattat
    55021 agcgtgcgtt ttcttttttg taaatgcttt attttttatt tttctgtcta taccattcta
    55081 taaaacctat aatacgtgtg ttcccttcta taattttctc ctaaaaattt atttttttaa
    55141 gcttttttct atgaaatatt ttcttttgtc tattgacttg tgcaatcggt tgcgtttatt
    55201 atgaacgtat aaaacagctc attaggagga gaaaaatgaa acagatcaaa cgactatttg
    55261 ctattgatcc atggaaaatc agcacgacac aattagataa aaaaaatctt cgactgcaag
    55321 aatctttaac aagtattgga aacggttata tggggatgcg cgggaacttt gaagaaactt
    55381 actcagggga ccaccatcaa ggtacttatt tggcgggtgt ctggtatccc gataagacac
    55441 gtgtcggctg gtggaaaaat ggttatccag aatactttgg aaaagtgatc aacgccttga
    55501 actttatcgc gatagatatt tcgatcaacg atcagctgat cgacttggct tctttggaac
    55561 cagaagactt ttactgggaa ttagatatga aaaatggtgt attatctcgt acattcacaa
    55621 tcactacttc tactaataaa gtacgcattt ccttcgaacg ttttctgagc attgtcaaaa
    55681 aagaatcagc ttatatctat ttaactatag aaatgcttga aggtagcgga acagtcaaac
    55741 tcgtatcaaa attggatgga aatgttcaaa acgaagacag caactatgat gaacattttt
    55801 ggaatgagat tgatcgtgga actatagaag aaatcggcta tttgacgact aaaactattc
    55861 caaacaactt tgggattgaa caatttactg ttactgcagc aatgcgccat ttcgttaatg
    55921 gaaaatcagt catccctgac tatcacgaag atactttagc attacatggt tgcttgtctg
    55981 cagaattatc tcaaggtgag acatggtcag tggaaaaaga aattatcgtt cttactagta
    56041 gagatattcc agaagcgcag caagcagaaa aagctgtctc agaattaacg aaccagacaa
    56101 acaattatat ccaagcaaaa gaagagcaaa cagcggcttg ggcagaacga tggaagcttg
    56161 ccgatgtggt catcgaagga gacgaagaag cacaacaagg tattcgattc aatttgttcc
    56221 aactattctc tacttactac ggcgaagatg aacgattgaa tatcggcccc aaaggattca
    56281 caggagaaaa atacggcgga gccacttact gggatacaga agcgtatgct gtccctcttt
    56341 atcttgcttt agccaaacct gaagtaacta agaatctgct gaaatatcgg cataatcaac
    56401 tgccgcaagc aatccacaac gctcagcaac aaggattaaa aggcgcgctt tatcctatgg
    56461 tcaccttcac tggtgtcgaa tgccataacg agtgggaaat cacattcgag gagattcacc
    56521 gaaatggcgc gattgcctat gcaatctaca attatacgaa ttacaccggc gatacggaat
    56581 atttgaaaaa tgaaggactg gaagttttag cagaaatcgc acgcttctgg gcagaccgtg
    56641 tccatttttc aaaacgagca aataaataca tgatccacgg tgtgaccggc ccaaacgaat
    56701 atgagaacaa tatcaataac aattggtata caaatacgat cgcagcttgg gtcttgcgtt
    56761 acacgcgaga aaattattta acttatcaaa aagaagctgc tatcactatc agcgaagaag
    56821 aactagccaa atggaaagat atcgcagaga acatgtactt cccagttgac gaagaattag
    56881 gaatctttgt ccagcatgac acattcttag ataaagatct catgcctgta tccgatattc
    56941 ccacaagcga tcttcctctg aatcagcatt ggtcttggga caaaatcctt agatcttgct
    57001 tcatcaagca ggcagatgta ctacagggga tttatttctt caatgatact tttacaaaag
    57061 aagaaaagca aaaaaacttt gatttctatg aaccaatgac tgtccatgag tcttcccttt
    57121 cgccaagtat ccattcgatt ttagcagcag aattaggaat ggaaagcaaa gctgtagaaa
    57181 tgtaccagcg aacagctcgc ttggatttgg ataattacaa taacgacaca gaagacggct
    57241 tgcacatcac ttccatgact ggtagctggt tgtcgattgt ccaaggattt gctcaaatga
    57301 aaactaccca tgatcagttg agattcgcac catttctgcc aaaaacttgg aaagcttatt
    57361 ctttccatat caattatcgc ggacgtttat tgttcatctc agtcacagat gaacaagtta
    57421 ctttcgagtt attagaaggt tctcctctag aaatttacgt ctatgaacag tcttattctt
    57481 tagcggatcg tctagaaata acgctaagaa aggaggaagc aaatgtttaa aggggtattg
    57541 tttgatttag acggtgtcat taccgatact gctgaattcc attatcgtgc ttggcgaaag
    57601 cttggtcagg aaatcggcat tacgatcgac cacacattca acgaacagct aaaaggcgtc
    57661 agccgagaag actcactctc tttgctttta gcttatggcg gaaaagaaca ctctttttca
    57721 aaggaagaat ttgcagaatt agcgaaaaga aaaaacgatt attatttaga gatgatccag
    57781 acgatcgaac caaaagatgt cttccccggg gtcgtgcctt tactggattc tttaaaagaa
    57841 gaaaaaatca agattgctct tgcttctgca agtaaaaacg ggccattcct acttgaaaaa
    57901 atgggtctta caccttactt tgatgctatt gccgacccgg cagaagcaac aaacggaaaa
    57961 cctgcgccag atatcttcct ccttgcagca aaagctgtcg gactaaaagc agaagaatgt
    58021 atcgggatcg aagacgcgca agccggtatc caagccatcc tctcaagtgg cgctcaacca
    58081 attggcgtgg gacgtgctga agaccttgga gaggagatcc cgcttgtccc tgatacgact
    58141 tttcttacga tcgattactt gaaagaaaag tggcatgacc atggataatc cagagatctc
    58201 cgtcgtacca gttccagaga ctgaaataaa gaaaatcaca ttgaagaacg actacttaga
    58261 agtcgttctt ctcaattacg gtgcccgcct gcaccaaatc ttcgcaccag acaaagaagg
    58321 aaaatcagaa aatgttttat tgtcttacga tcgtttcgaa gatgttctaa cagacaaaag
    58381 cttttttgga gcaactgtcg gacctgtagc cggaaggatc cgggatgctt cttggggtga
    58441 gcatagattg gagaaaaact gcggatcaca ccatatccac ggtggcacga aaggctggtc
    58501 tttccaattt tgggaagtag aagttttcaa aactccatca tcaataggtg tggtctttta
    58561 cttaaaagat gaattttcta cctatccagg accaatcact gctacgatca cttaccgttt
    58621 aacaaaaaac gaattagaga tgacaacctc tgctagtagc cttgttgaaa ccatctgcaa
    58681 tccgaccaac catgcctact tcaacctttc aggaaatgga acaagagaca tctatgaaca
    58741 tcagttaacg gtctttttag atggtgtgct tgaattagat caagaaaaac tgcctactgg
    58801 aaattggaca aaaaaagaaa aactgccaat cgactttaga aaatccccaa cactgcaaga
    58861 gatccttgca tgttatccag atggactaga tgatgtattt cttttgcatc atcctaggct
    58921 ttccaaaact tccttacaat tattcgagaa gcattctggt cgccaaatga ctatagcaac
    58981 ttctaataaa agtatggtat tattttctac gactggattc gaagctgatt tctctgtcaa
    59041 tggaaaacag atgcattcaa actacggatt agcaatcgaa ccgcaagaaa tccctgatat
    59101 cgttcatttc cccaaatttg gatcgatcaa cctccatcct ggtcaagaac ggatcagtca
    59161 gacgatttat cggttctctg cacaataaca agagaaaggt gtttttatca tggctattac
    59221 cgtaaaagat gtggcgaaaa aagccggtgt tgccacctcg accgtctctc gtgtcatcaa
    59281 cgatcatcct agtatttccg agacaacaaa gaagaaagtc cgaaaaatta tggatgaact
    59341 aggttatgtt cctaacatga ctgcccgcaa tctaggaaaa cgcatttcca gtgccatcgg
    59401 cgtaatctta ccccctcttg attcaaaaga gcggatcggt aacccatttt atcttgagat
    59461 catggaagca atcaacgaag aagcgcggaa ttatgatatg actacagcaa tcgctactgc
    59521 taaaaatttt gaattgctgt tagagaacgt ccagcgtatg catttacaaa aacaagtaga
    59581 tggttttatt ctagtgtatt cagatagtca agatactgtc attgattatt tataccaaaa
    59641 ccacatccct ttcactttga tcggacagcc ttatcatcat gagaacgaaa tcgtttatgt
    59701 agataatgat aaccagcttc taggtaaaca agcaacagaa tttttgatcc agaatggaca
    59761 taagaatatc ctgtttgtga caaacacgac tcatgaaagt ttgtatttcg aacgatattt
    59821 cggttatcaa aaagcaatga tgatggctgg tcttcctgcg ttatccagtg tagtactaga
    59881 gcatccggag gattatctgt cctttgagaa aacgttgaaa gaaaacgaag ccacagcatt
    59941 ggtggtcatt gacgatatct tcgcccttcg cacgatgcag ttggcgcaaa tgtatggcta
    60001 tgtcattcca gagacactct ccgtcattag cttcaacaac tcgatcttct caacattaac
    60061 acacccttac cttacaagta tcgatatcga tatctccgaa ttaggacgtg tcgctatgca
    60121 aaagctgcgc gaattgatcc atgaagaatt gagcagtggc gtacgtttgg tcatccctca
    60181 tcgcttgatc aaaagagaga cagtcgttcc tttagaaaac ccatactaaa tagctgactc
    60241 actaaatacg ctgaccattt atcctatggt cagcttttta tgtaaaagaa gatactactt
    60301 ctaacacatt gtttatctgt aaaaaagagc gtgggacaaa agtaaagaac acttttgtct
    60361 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa
    60421 attcacaaaa atttaaaaag caattttctt gagtttcttc ttatttcttg gagttaaacg
    60481 cttctgtccc agcctctttt ttccttcctt caatttttta cacgtcgacg attcaataaa
    60541 aaaccgccta atattgtaaa gacaggtgca agaatcgaga aaaaggcgaa tggcaagtaa
    60601 tgcaacgcgc taactttcat cgttcccata atgaatgtgc cgctgactcc ccacggtacg
    60661 agagaattga cggtcgcacc tgaatccgct agtgttcgtg tcaaataggt ttttgataag
    60721 ccaacgtcat caaaagaacg cttgaatgtt tctcctggaa gaatgatgga cagatactgt
    60781 tctccaacga tcagattgat tccgatacag ctcaaggcag taaacccgac taaacgagaa
    60841 ggtcggtcca tcttttcttt taattcttga acgatggtat caacgatcag atatttgatc
    60901 agtaacccac ctaatgccaa tgcaagtaaa atcaaactag cagaacctaa catactcatg
    60961 atcccgcctc gagaaagcag ttcatctagc tttggatcag gtgtatttgc gacataacca
    61021 ttcatcaaga tgtctgctgc ttttccgacc gtcaaacttt tctcatggat aaaagaaaga
    61081 acgagagcag ctgtcgatcc cgctagtaat gtagggatag ccggaatttt tttgattgcc
    61141 cccccaaata aaataactag tggaatcaat gtccaaggag agatccaaaa gctcgctttc
    61201 atgttttgga tcatttcatt gatactagct agatcggctg aatgactgtt atgtcctaat
    61261 atcgtataaa aaatcaacga aaggacgaat gctgggaaat ccgtataacg cataccagcg
    61321 atatgttcga atagattaac tcctccaata cccgctgcca agttggtcgt atctgataaa
    61381 ggcgagcagt tattccctaa aaaggcaccg gaaacgactg cgcctgtagt cattgcatca
    61441 ttgaatccaa gtaaatgacc gatccccaaa aaagcaattc caatcgtcga aatcgttgta
    61501 aatgaactgc cgacagtcac tccgacaatt gcacaaacaa gaaatgctgt cggtaaaaag
    61561 aaacgcacag aaacaagttt aaatccataa accataatcg tagggatggt tccagataaa
    61621 atccatgaag caactaagac accaatcaaa agaaaaatca ggattggaat gatccctgga
    61681 gtgattcctt tgatgatccc gtcatggatc tcatcccatg tgaacttttt aaatctgcca
    61741 taaaacaaca aacacatgaa agctgcaagg atcgggatat gtggcgagag ctggaatccg
    61801 atgatcagta ctcctaggag tgccaacaac acgatcaata cagcgatact ttcttttaaa
    61861 gaaatatttt tattcatcgt cgatctccta tttcaaatga aaaggccctg ccatgaaaaa
    61921 actattcact tggcaggacc tcctactaaa tcagcgacaa aacgtcggct gaaagactta
    61981 tttttttatt tttcttctaa acttttttct acctcaatcc cccaagaatc tttcttgaag
    62041 tgattgatga tcaatggaat aacgaacatg accactgtga tagctgctac taataatgca
    62101 tcactcaatg tcgctgtacc taatgtagca aatacgacaa cgatgataga gaagatcagc
    62161 atgcagctga ctacccaagc taatccgttt ccgtttttac caattcggta aggacgttcg
    62221 aattctggat gtttcttacg cattttaagc aatgaaacag caatcaaaat gtacacgata
    62281 caataaataa cagttgtagc atttgtaagt gtcaagaata cagcacttac gtcatccatt
    62341 acaccataaa gcaaagcaaa taatgaaata acgattgatt gtgttagaac gacatttcta
    62401 gatacgccgt atttgttttc tttatggaat ccgaattttg gtggaaggaa tccttcacga
    62461 gctacttgga tgattgtttt tgatggtcca gtaacccaag ctgataattg taaaagcaca
    62521 ccaataaata ccatgaagct gaagatattt ccgatcactt ctggtaagcc taggatttga
    62581 cagtcaatca agataggctg cgtgatattt gctaattcca tttttccatc tggtacgaca
    62641 tttgctacaa gcatcgcatt gatgacattc aataaaacta atccgatcaa agcgataaat
    62701 acgccttttg tataattttt tgttgcgtct ttcaaacgag gcatgtaaac agaactcatt
    62761 tcgatcccaa caaaaataaa tgtgatacca gctaagtatt tcaatgaatc aatatgttcc
    62821 aagtcaggga aagcttttga ccatgaaaag tcacctagat agccgtttga gactagtccg
    62881 actttgaagg ctgccaaaac acctaaaacg aacatgatga ctactgggat atatacccct
    62941 agccatacac cgatgttccc gccgactttt gccatatcga atttcaagtt caagatcgtg
    63001 atgatccagt agataactaa aatacaacct aaaacgaacc agtgattatt gccaagttct
    63061 acattaccaa atgtgtttcc taacaatggt cctaaagtag aagcgaccat taccatacct
    63121 gggaacattt gcacccataa tagccatgca acgacaaatc cccatttgct gcccagtgct
    63181 gtttttaccc ataactgagg accgccttct tgaggaagca tcgtggaaag ctcaccggaa
    63241 accattgata tcggaccggc aaaaaacaaa actgcaaaaa ttgaataaaa aatcaatgtc
    63301 caaccgactg cggctaacgt aggaatactc cgaaccgttg cacacagtgc cattgtcaga
    63361 ccgataaagg tcccaagacc cattttactt acttcagatt tactcaccgt tgacactctc
    63421 cttgattttt tggataaaat aacggtgtct ttgaagtagt ttcagcaata aacgaaacaa
    63481 ttcagcgaat atttgagggg attctttgag tttattgctt gaagggtttc ttcaaagaca
    63541 acctcaaaac aaagggatcg aagagcttag gtctcccctt gctcttcaga tccaaacatg
    63601 cgtcagaaac agttagtatt caagctgttt tctaacatga ttaccttgct tattttgctt
    63661 cgcttgccaa taattggtct gcgtagattt tttccaattt ttcttgaaga gctgctttga
    63721 ttttttcagc atattcttca aagtgttctt ctttgttcat gtatggtgtc attacgctgg
    63781 cacgcaatac agttactttt ccggcacggt tccattcttc atctgagaat cctagttggt
    63841 tcacaaattg taatgggctg ttgccatagt ctgggatagc aaagtcagta tgtgaagtta
    63901 agaactcatt accgtaaatg cttcctttca cgtatgaaga ataatcatat acgtcatggt
    63961 tcaatttatt cattgcaact aagtcatcgt tgcctttttc tttgaataca tagtctacca
    64021 tattgaaatc tggataagtt aatggatgaa cttcgatttc tttgtctcct actttaaatg
    64081 acaagtcatt caagaagttg tagaaacgat gtgcaccttc gattgatgca cccattaatt
    64141 taccatatcc tgtgacattc aaaggtaaga catggtgtgc tgcccaaacg ctggctgctg
    64201 ttgcccctgc ttttgaacct tccaagatat aagccccaag taatgctggg atatctgcgc
    64261 ctttttcaaa tacatatgtc gcaaagtaag agataacgtc tctcatgcgg atatctttga
    64321 tgacgatacc accggcagaa tatggaacat agcccatttt atgtgggtca atcgttacag
    64381 attctgcttc ttcgattgct ttatatgcac tgtgtacttc ttctaagata taatctttgt
    64441 tttctgtaaa gacattgtat ttgtaatgaa catcttttaa atcttcaaat ggaatgaagt
    64501 tgttgtcttc gtctaagaaa atcgcacggc cgtatccgcc ataagcagca tctacgtgta
    64561 agtagaagta aataccgtct ttttctaata cgcgacgcaa tgcaacgatt ttatcgatac
    64621 cgtcgattgc tccttcttct gttgatccta caacaccgac tacacctagg attggtgttt
    64681 tttcagctgc tagaccacga acgatttttt caagttcgtt gatgtccatg cgatagttgt
    64741 ggtcaactgg cactggaatc acttggtcta aaccgatacc gatgatgtcg gcagctttta
    64801 gccatgaata gtgtttagtt tgtggaacca accattttcc taatttttct aaatgttttc
    64861 cgctacgtgc tgagtgagct ttgatttcgt cgattttttc tgggacgctg tctaacagat
    64921 tcatgatttc ttctgttgac aagttcatta attcccaatc gctttttcca gcaactagtt
    64981 caggtgtcac ttctttcatt gcaagcggca atgatttgat gttgcgggca taccaaagtc
    65041 cttctaagtt tgctaaagaa ccatcagcaa cgatgtggcc ccagccatct ttatagctca
    65101 ttaattttgc aaattccatt cctacttctt cttccatttg gcttgttgca ggagaagatt
    65161 cataggcaac gttattacca ttccatagca tagcaaaatt gtacgctagt aaagatggca
    65221 tcaatgtttc agagttcata tgaccccagt aacgtccggc attatgccaa ggaacggaat
    65281 gggtacgcat ccgcgctgaa atttctgata gaacatcctt tgttttattc acagtgtgtt
    65341 caaaactagc actgcttttt tcttctggcg taataatagg catgtcttga ggcatgtagt
    65401 tttgacgcca gcctaaatgt tcatccacca attcattcaa caaagcttta tagatttggc
    65461 cgttctcagc tttgtcccca atgaataggg catttaggtt tagatctttc gacaatgatt
    65521 cactcatagt gaaaccctcc taaaaaaata tttaaatttt gtcgagccct acattacacc
    65581 tgttcttcta ttctgtaaac taagttttgg cctgattttt aatcatattt taatatgtat
    65641 caattatccg aattgttcac acttttgaaa taattaaaaa aaacgaggga atttacaaat
    65701 gtaaactccc tcgcaaagat tgtattaacg acaaccagcg ttctatttta ggatgggttt
    65761 caaaattgga atgttgtaat agtatttccc ttttttaagg taaaaactta ctaaattcta
    65821 atcaattact ttggccaaaa agtaattttt cttacctttt cgaataacca caaacttacc
    65881 atcgaattca tcggatggat ttatgacaaa atttaaatcg gtaacgcggt caccgttaat
    65941 acttatagct ccgtttgaaa catcttcacg tgcttgacgt ttagatggtt caatttttgt
    66001 ggaaacaagc agttccacga tattttcagg tgtgcttgaa atttcaacgt tcggcatttt
    66061 accgaatcct tgcgcgattt cttccgcatt tagttcttta atatttccag agaacaatgc
    66121 ttgcgttatt ttttgcgctt ctttcaagtc ttcttcacta tgcacaaatc ttgtaacttc
    66181 ttctgccaaa cggcgttgtg cttcacgttt ctcaggttct gtctctactt ttttcgctaa
    66241 gtcttcgatt tcttcttgag acaagaaagt aaagaatttc aagtatttca ctacatcgcg
    66301 atcatcttga ttcaaccaga attggtagaa ctcaaatggt gaagttttct tcggatcaag
    66361 ccaaacggca ccgcctgcag tttttccgaa tttcgttccg tcagccttca gcatcaatgg
    66421 gatcgttaaa ccgaacgctt ctgcttctgg tccttctaat tttcggatta ggtctaatcc
    66481 agctgtgata tttccccatt ggtctgctcc accgatttgc aattgcacat cgtatgtttt
    66541 atgcagatgc aaaaagtcga tagattgcag gatttggtaa gtaaactctg taaatgagat
    66601 tcctacttcc aaacggctgg caacgatatc ttttgctaac atcgtgttga tgttgaagtt
    66661 tttaccgtag tctctcaaaa attcaagtaa agagattttt gacaaccagt cgtagttgtt
    66721 cacaaatgtg atatttgcat ctttaccaaa caattttctc atttgattgg aaagtgcgtc
    66781 cacgttatgt tgcacttgtt ccatcgtttg caacacacgt tctgttttgc ggccgcttgg
    66841 gtcgccgatc gttcctgttc cgccgccaat cagaatatat ggatgatggc ctgccaattg
    66901 gaatcttttc atcatcataa atggaatcaa atgtccgata tgcatcgaat caccagttgg
    66961 atcaacgccg caataaagtg aaatgctctt ttcttcaacg agctcgcgaa gtctttcttc
    67021 gtttgtttgc tgattaatgg cgtcgcgcca agttaattca tcaataatat tcattttact
    67081 gacctccgtg tagttttttt atgaaagcag gaacctgcta gcatatgtaa ttaattattt
    67141 cttcaggata ggataggaaa taaaaaaagt cccttggcat ataagccaag ggacgaaatc
    67201 tcgcggtacc acccaatttg tatgtctaga tatccaacat acctctcgaa catttaacgc
    67261 tgtcgcgtgg caatcactgc caaagactcc tgaaatgtaa ttcgctttaa agcatgtact
    67321 ggtttgcagc gaccaccagc tttctgaaac attggcttta acaactactt cgtttcgatc
    67381 ttcgtcttgt tattattaat atgtgtctat catagagcgc aactttttct ttgtcaacag
    67441 aaaaaggata ttttttttaa attcctcatt ttttcttttt tgaatccgct ctaattccga
    67501 acattttatt ttcaattatt gttaaaagaa ataacttttt ctgtattttt tctgcaattt
    67561 atcgagaagt cactttactt tgcctcttat tctttcttcg ttacaataag gaatgggaca
    67621 agtaaaaaaa tgaaaaagca agggacgagg tatatggaaa aaaagcaaaa aattatttta
    67681 ggagccactt ctgctttaac tatcgttatt ttaattctaa gtttgttttt tgtcatccga
    67741 tcatctacaa aaaaagaacc aatcattcct gaaaaaaaaa taacagaaaa agcaaaagaa
    67801 ccgacagatg ataagcaaca actagttact caagcaaaaa atctggctca aagctacgat
    67861 tatgaccaag cgattgcgtt attggaaaaa gatagtaaga acggatctac tgaaacacaa
    67921 cagcttcttc aaacactaaa aaaggagaaa gaacaactga tcgactggtc tgatcctact
    67981 cagatctctc atgtcttttt ccacagcttg atcgtggacc cgcaaaaagc cttccactct
    68041 caacaggcac aaggatacaa agattatatg gtgactgttg aagaattcaa ccgttcgatc
    68101 gaacaacttt atcaaaatga ttttgtttta gttaatttga atgatttgat ccaaaaagac
    68161 gaacaaggaa atctttcctt taacgggctt gcgctacctg aaggaaaaaa accattggtt
    68221 ctttcacaag atgatgtcag ctattatgaa tatatggata attccggttt tcctagccga
    68281 ttggtcgtat caaataacaa tgaaatcaaa aatgtctata aagagaaaga taaagaagaa
    68341 atcggtgact ttgacatggt tcctctgatc gatgcctttg tcaagaaaca tcctgatttt
    68401 tcttatcgag gcgcaaaagg taccttggcc ctgacaggtt acaacggagt tttaggttat
    68461 cgaacatcaa aatctcaata tggagacaat gaaaaaacaa aaaaagagat taaagaagct
    68521 aaaaaagtgg cggaacagtt gaagaaagac ggctggagct ttgcttccca tacatggggt
    68581 cacttgaata tgactcaagc ttcactagaa gatgtaaaaa aagacaatga attgtggcag
    68641 caagaagttg cacctatcct aggaaaaaca aatattctga tttatccatt tggtgcagac
    68701 atcagcgact ggcagcctta ttcagcagaa aatcaaaaat ttgcttactt gaagagtcaa
    68761 ggtttcgata ttttctgtaa tgtcgatgct tctacaccag cttggggaca attaggtacg
    68821 gatttctatc gaaatgctcg gatcaatatc gatggcattc gttttcaatc tgatttagac
    68881 ggaaaaaatc ctattcttga tccattcatc aatgtccatg atgtctatga caaagaagca
    68941 cgcgaatctg cttgatttta cgtcatttat gaaccaaaaa agccgaactg acattttatc
    69001 gtcagtttcg gcttttttat gctttatttc ttcttcggtg cgattccctt gatcaggact
    69061 tctgtccatt ctgctgtata tggaagcagt tttgcgtata tctccggctt agaaattcct
    69121 tctaccattg cttgaaaata gaggatcaag aactcatccg aatatttcaa atccactttt
    69181 ccttctttcc gccctcgatg gaaaagatca agcatgatac tgaaactttc ttgcgtatac
    69241 gcatccatcg cgtcagaaaa ttcttttttt tctttttttg tatagtatgt catcaaatcg
    69301 atataaaatt gtttgttcac tcgattgaga taacggattt tgttttcact catggcaatc
    69361 agtgtttctt caaatggaag attttccgca atcaacgctt tcgcttcttg ccctaaatca
    69421 ttcataaatg caaaaaatac ttcataaatc agcccttcct tgctgccaaa atatttaaaa
    69481 atcgtcgctt tacttacctg agcgttctca gctaccttat ccattgtcac tccagcggtt
    69541 cctatgtctg tgttcatcaa gtcaaaagct gcttgtaaaa tctctttctt tttctcttgt
    69601 gctctctttt caaaaccgtt catttgtaga gcctcccgta attttaaact tttataatat
    69661 gtatagttca aatttattct gaggtttatt ataactatct attgagaaag tatcaagcta
    69721 gcaattcctt gtttatgaat tcattgacag aaatttataa aaagaatatt atgtactaaa
    69781 ataataaaaa aagttttata aaaaggtata aaaccttttt attaaactat ttaatcttgt
    69841 ttagtatata tttttagaaa aaggagtggg gtttttatgg cagaaatcgt caaagtcaca
    69901 catttgaaaa agagctttgg tcgtttcgaa gctttaaaag atgtctcttt caccgtacat
    69961 tcaggtgaag tcgttggatt tatcggacca aatggttctg gaaaatccac gacgattcgg
    70021 acacttttag ggattataaa aaaagacggc ggaacggcaa cgatttttgg gcaagatgta
    70081 tgggaagata gtttatctat ccatgaacgt ctttcttatg ttccaggcga tatctctttg
    70141 tggggaaatt tgactggagg agcgatcatc gatctcttca tgaagcttca tggaaaaggg
    70201 agtgctcaaa aaaaagatga actgattcaa cgtttctctc ttgatcctaa gaaaaaagca
    70261 aaaaactatt caaaaggaaa tcgccaaaaa gtgggcttga ttgctgcttt ggctgttgat
    70321 tcggatctct atttatttga tgagcctact tctggtttag atcctttgat ggaaacgatt
    70381 ttccaagaag aagttgaaaa attgaaagaa cagggcaaat ccatcctact ttcttctcat
    70441 attctcagtg aagtcgagcg actagcggat aaagtcgtga tcatacgcga aggaacactc
    70501 gatgaagaag gaacactcga tgaattgcgt catttgactc gttcgaccat cactatagaa
    70561 acagaagcag agaatagtca cttagcacaa ttgaacggtg tccatgactt tgtgcaaaaa
    70621 ggtcacctcg ctcaatttgc tgctgataac gaagctttcg atgtgatttt agctgaagcg
    70681 tccaaattag gtgtgaaaaa atttgaatct attccaccga ctcttgagga tttattcatg
    70741 agacattatg aaggatgagg aggaagcgaa atgactgata aattttcacg ctggtccacc
    70801 cttttttctc aaaaccttag ccgtgactgg aaaaagatcc tgatatggct agtcggtgtc
    70861 actgcttttt ctggtggttt tgtccctgcg tttgaagaat tgacttccgg acaaggatta
    70921 gctggattat acgaaacctt gcaaaacccg gcaatgattg caatggtcgg accaactcca
    70981 gcttcgaatg ctgctgagta tactttagga gcgatgtatg caaatgaaat gttgcttttt
    71041 tgcagtttgt ttgctgctgt gatctctgtt ttacacgtgg tgagccaaac gagaaaaaaa
    71101 gaagaacttg gtctgattga acttattcgt tcctttcgag tcggacgtca agcaaactct
    71161 ttagctgtca tcgctgaaag tattctgatc aatttgcttt tagcaatatc gatcagctgt
    71221 acgatgattt ttttccaagc ggattcgatc actgcagaag gtgcttggct ttttgggcta
    71281 tctgtaggta gtatggggat tttggggagt gccgttgcac tgtttgctgc acaactgatg
    71341 ccaagttcag ccagttcgaa tggtctgtct ttagcgtttt taggtggact ttaccttcta
    71401 cgagcaataa cagatgtagc tgattcctcc ctttcgatgt ggaatccttt aggctggtct
    71461 tatttgacct atccatttac aactaacaac tggattcctt tgctttattt gtttttgttc
    71521 agtctaatct tgataatcag ttcatttgtt ttagaggaac atcgagattt gaacaccggc
    71581 tatatccccg aacgtgaagg aaaaccgtat gctaaacgtt ctcttttatc cttgcgtggt
    71641 ttattattct atctaaataa agggatgaca atcagttggc ttatcacttt tggtttgatg
    71701 ggggcggcat acggctctat ctacgggaat atgcaacagt ttttagaaag taacgactta
    71761 atgaaacaga tgtttatcca atctggcgtc tcaattgaaa aaaactttac aagcacgatc
    71821 atggtagtct tgatttgtct agctgctatt ttaccaattg ctagcatcaa tcgtttattt
    71881 acagaagaaa cccacggacg tatgaatcag ctgttcgcaa caaaaatttc taggaaccaa
    71941 ctttattgga ccaatatgtt actagctatt ctatttgcta tattggcaat cctgattagt
    72001 tctggtgcac tagggctttc tgctttggct tcgatgaagg atgcgaaaga catggatcta
    72061 ttgatgtttc ttaaagccgg gttcaatttc ctgcctgccg ttttagtgtt tatcggaatt
    72121 agtggctttc tattcggatg gcttcctcga atcggtaaac ttgcttatat ctacttagct
    72181 tactcctttg cactcaatta ctttggcgga attttggatt taccagaatg gttttccaaa
    72241 acagctgtcc ctagctgggt tccacggatg ccaaacgatt cttttgatct ttccgtgttc
    72301 cttacgttat catgtatcag ccttgcactg ttcgtccttg gttctattgg ttataggcga
    72361 agagacttac tagaaggata ataaaaaagc atgtacaatt tcatgctagc ctccaaatct
    72421 gggtcaaaaa tccaacattt ggaggtcatt tttttattta caagtcttct aactgctctt
    72481 tatcaatgat ccagacttct cgattctttc tttttacata accattctcc tctaataatt
    72541 taaattttct agataaagtt tcgggggtcg taccgataaa tgcagcaagt tctttcattt
    72601 tcattggcag gaaaaagtga tccttccctg tcgctttagc taagtcaagc agatagacag
    72661 cgactcgttc ttctactttt tccatcatca aaaaagttgt ctgctgctgt acttttgtta
    72721 atttctcaac gttgattgct aaaagtttca gactaagggc gggataatgc agtaagagtt
    72781 ccgagaaatc tttttgtctc aatatgcaaa tttccgtttt ttctagtgct tcgccaaata
    72841 aagactcatt tggaacgcct agcaactggc tctctccctc atatccgccc ggctctatta
    72901 ctcgtaaaag ctgttccttt ccgctagcag ataattgata cactttcata ctgccggagg
    72961 ccacgatcac taattgaggt tctccattcg gcgcaagaat ctgttctcct ttttccacat
    73021 agtgatgttt gacaagtgcg tgtacttttt cttgatcttg ctgtactaag tgattgaaca
    73081 aaggaacaaa tgaaacacat aaatgatcat gactcataat ctctcctcct tctaaacagc
    73141 tatttctaat aaagaaacat aacttccctt attccaactg ataattttct tttatcatag
    73201 cataaacgtc aagcgaacca gataccagca aatagagtgg atttcttttt gtcccttgct
    73261 ttattttcct tcttttgaga ccttaagtaa ttgattccta tcaatttttt aaatatttac
    73321 tttttgaata atcaaaaaca aaccttcact cgcaagccga gagtaaggtt tgtttttcgc
    73381 attgcttatt tcgtgttgtc tattgaaatt tttccgcacc tagcttttga tatagtggtg
    73441 ctagttcttg taaggtttca gcggttattt gctcaacgtg ttcgatttct tgcggataga
    73501 agaatagttt acccatttga aaggttcggt ctctcatcgc ttttttcaac tcttcttgtt
    73561 tctttgtatc ggacaaatag tcagacaaag ctaagtggtc gtcaagttca tgttctggtt
    73621 gcggccatat gtaataatcc ttgatatcga ctgttttgct ccactctttc agtatcgcaa
    73681 gcaactggtt atacgctgca atgctaccat atcgttcttc gcttttataa tgttggtaca
    73741 tcaaatagat ttggtattgt ttttgattca acaaaactgc tagacaggca ttctcgtctt
    73801 gacgagattc gcttcggtac gcgctccaaa aatgactgcg taaattccag ccattcgtcc
    73861 agctttcgat tttaggtttg ctcatgccgt acatatcagg caaaagtgca gctgtctgga
    73921 gctgaatctc tttccatttt tgccagtgtt ctttatattc tttcttgatt tgttcaatct
    73981 tatctgttgg atggctctct ttgagctgtt tgaatgcgta gattggtcga tcaaacaact
    74041 gataatctga ttttccaagt tccattgttt cgcctctttc cgttatcttt tgtattctac
    74101 ctgaattttg cgatatggac aaatagaggt tgtgaaaaag ctgttctgca tcaagtcata
    74161 agaacagcca aacaaaaaac tgcgatgagc atcaccgcag tttt
//
LOCUS       DAIGUC010000003        73749 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.003, whole genome shotgun sequence.
ACCESSION   DAIGUC010000003 DAIGUC010000000
VERSION     DAIGUC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.003"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(218..934)
                     /locus_tag="NOB46_000153"
     CDS             complement(218..934)
                     /locus_tag="NOB46_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI1057142.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(935..2758)
                     /gene="glpO"
                     /locus_tag="NOB46_000154"
     CDS             complement(935..2758)
                     /gene="glpO"
                     /locus_tag="NOB46_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HCI1057143.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(2772..4268)
                     /gene="glpK"
                     /locus_tag="NOB46_000155"
     CDS             complement(2772..4268)
                     /gene="glpK"
                     /locus_tag="NOB46_000155"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCI1057144.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(4404..5864)
                     /locus_tag="NOB46_000156"
     CDS             complement(4404..5864)
                     /locus_tag="NOB46_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057145.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(5854..7149)
                     /locus_tag="NOB46_000157"
     CDS             complement(5854..7149)
                     /locus_tag="NOB46_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1057146.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(7481..8158)
                     /locus_tag="NOB46_000158"
     CDS             complement(7481..8158)
                     /locus_tag="NOB46_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HCI1057147.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(8188..9279)
                     /locus_tag="NOB46_000159"
     CDS             complement(8188..9279)
                     /locus_tag="NOB46_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HCI1057148.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(9380..9814)
                     /locus_tag="NOB46_000160"
     CDS             complement(9380..9814)
                     /locus_tag="NOB46_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1057149.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(10398..11855)
                     /gene="ascB"
                     /locus_tag="NOB46_000161"
     CDS             complement(10398..11855)
                     /gene="ascB"
                     /locus_tag="NOB46_000161"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI1057150.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(11852..13747)
                     /locus_tag="NOB46_000162"
     CDS             complement(11852..13747)
                     /locus_tag="NOB46_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1057151.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(13805..15580)
                     /locus_tag="NOB46_000163"
     CDS             complement(13805..15580)
                     /locus_tag="NOB46_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI1057152.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(15630..17126)
                     /locus_tag="NOB46_000164"
     CDS             complement(15630..17126)
                     /locus_tag="NOB46_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1057153.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(17320..18942)
                     /locus_tag="NOB46_000165"
     CDS             complement(17320..18942)
                     /locus_tag="NOB46_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI1057154.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(19270..20583)
                     /locus_tag="NOB46_000166"
     CDS             complement(19270..20583)
                     /locus_tag="NOB46_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI1057155.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(20864..21052)
                     /locus_tag="NOB46_000167"
     CDS             complement(20864..21052)
                     /locus_tag="NOB46_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057156.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKE"
     gene            complement(21072..21494)
                     /locus_tag="NOB46_000168"
     CDS             complement(21072..21494)
                     /locus_tag="NOB46_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HCI1057157.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(21639..22349)
                     /locus_tag="NOB46_000169"
     CDS             complement(21639..22349)
                     /locus_tag="NOB46_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057158.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(22367..22864)
                     /locus_tag="NOB46_000170"
     CDS             complement(22367..22864)
                     /locus_tag="NOB46_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1057159.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPKHLADYLTQAYAPEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(22901..23353)
                     /locus_tag="NOB46_000171"
     CDS             complement(22901..23353)
                     /locus_tag="NOB46_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1057160.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(23488..24093)
                     /locus_tag="NOB46_000172"
     CDS             complement(23488..24093)
                     /locus_tag="NOB46_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI1057161.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(24648..25283)
                     /locus_tag="NOB46_000173"
     CDS             complement(24648..25283)
                     /locus_tag="NOB46_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI1057162.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKKSMTISNKEMA"
     gene            complement(25285..26154)
                     /locus_tag="NOB46_000174"
     CDS             complement(25285..26154)
                     /locus_tag="NOB46_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HCI1057163.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYISMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(26177..26584)
                     /locus_tag="NOB46_000175"
     CDS             complement(26177..26584)
                     /locus_tag="NOB46_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI1057164.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELYENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRSD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(26603..27775)
                     /locus_tag="NOB46_000176"
     CDS             complement(26603..27775)
                     /locus_tag="NOB46_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI1057165.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAILWMATMTTVFGY
                     FAGLRGIVLILVGGFIGACFAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVA
                     KLFGEKGENKKSIEDIKLPTHFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGD
                     QNYIMFAFLQAIQFVVGVYVLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFP
                     YSPNAVILGFITTTIGTIIAMFTLPMFGLAMILSGMLTNFFAGGTAGIFGNAVGGRRG
                     AIIGGIAHGFFITLLPALLVTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(27802..28104)
                     /locus_tag="NOB46_000177"
     CDS             complement(27802..28104)
                     /locus_tag="NOB46_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1057166.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(28129..30215)
                     /locus_tag="NOB46_000178"
                     /pseudo
     CDS             complement(28129..30215)
                     /locus_tag="NOB46_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            complement(30704..31469)
                     /locus_tag="NOB46_000179"
                     /pseudo
     CDS             complement(30704..31469)
                     /locus_tag="NOB46_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
     gene            complement(31580..32449)
                     /gene="mdcB"
                     /locus_tag="NOB46_000180"
                     /pseudo
     CDS             complement(31580..32449)
                     /gene="mdcB"
                     /locus_tag="NOB46_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
     gene            complement(32474..33558)
                     /locus_tag="NOB46_000181"
                     /pseudo
     CDS             complement(32474..33558)
                     /locus_tag="NOB46_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
     gene            complement(33582..34175)
                     /locus_tag="NOB46_000182"
     CDS             complement(33582..34175)
                     /locus_tag="NOB46_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HCI1057167.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWATEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(34179..35855)
                     /gene="mdcD"
                     /locus_tag="NOB46_000183"
     CDS             complement(34179..35855)
                     /gene="mdcD"
                     /locus_tag="NOB46_000183"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HCI1057168.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDFIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEETIVISIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKFRQAGYPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(35845..36144)
                     /locus_tag="NOB46_000184"
     CDS             complement(35845..36144)
                     /locus_tag="NOB46_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HCI1057169.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(36246..37892)
                     /gene="mdcA"
                     /locus_tag="NOB46_000185"
     CDS             complement(36246..37892)
                     /gene="mdcA"
                     /locus_tag="NOB46_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HCI1057170.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVVADKADKDGNL
                     YTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADEPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALVVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLREAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(37899..38810)
                     /locus_tag="NOB46_000186"
     CDS             complement(37899..38810)
                     /locus_tag="NOB46_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI1057171.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLTFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEMVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            38930..39220
                     /locus_tag="NOB46_000187"
     CDS             38930..39220
                     /locus_tag="NOB46_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1057172.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLYTLEEGINYCLRSMRRSLLPSYCI"
     gene            39172..39786
                     /locus_tag="NOB46_000188"
     CDS             39172..39786
                     /locus_tag="NOB46_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI1057173.1"
                     /translation="MSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQH
                     HLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPIL
                     MLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIVKQGLAVSFFPKVSWSYDKN
                     DPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK"
     gene            complement(39973..40335)
                     /locus_tag="NOB46_000189"
     CDS             complement(39973..40335)
                     /locus_tag="NOB46_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCI1057174.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            40681..42118
                     /locus_tag="NOB46_000190"
                     /pseudo
     CDS             40681..42118
                     /locus_tag="NOB46_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(42125..44677)
                     /locus_tag="NOB46_000191"
                     /pseudo
     CDS             complement(42125..44677)
                     /locus_tag="NOB46_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(44791..46122)
                     /locus_tag="NOB46_000192"
     CDS             complement(44791..46122)
                     /locus_tag="NOB46_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1057175.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYSLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELAAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQMIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCTHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(46088..47566)
                     /locus_tag="NOB46_000193"
     CDS             complement(46088..47566)
                     /locus_tag="NOB46_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1057176.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPKKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(47871..49706)
                     /gene="tdc"
                     /locus_tag="NOB46_000194"
     CDS             complement(47871..49706)
                     /gene="tdc"
                     /locus_tag="NOB46_000194"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI1057177.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTTHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHMTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
     gene            50175..51602
                     /locus_tag="NOB46_000195"
     CDS             50175..51602
                     /locus_tag="NOB46_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057178.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQVSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRLTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERTDRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(51694..52059)
                     /locus_tag="NOB46_000196"
     CDS             complement(51694..52059)
                     /locus_tag="NOB46_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI1057179.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(52056..52421)
                     /locus_tag="NOB46_000197"
     CDS             complement(52056..52421)
                     /locus_tag="NOB46_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI1057180.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            52859..52987
                     /locus_tag="NOB46_000198"
     CDS             52859..52987
                     /locus_tag="NOB46_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HCI1057181.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            53044..54738
                     /locus_tag="NOB46_000199"
     CDS             53044..54738
                     /locus_tag="NOB46_000199"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HCI1057182.1"
                     /translation="MRKSKSIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKSNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            54742..54861
                     /locus_tag="NOB46_000200"
                     /pseudo
     CDS             54742..54861
                     /locus_tag="NOB46_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            54865..54984
                     /locus_tag="NOB46_000201"
                     /pseudo
     CDS             54865..54984
                     /locus_tag="NOB46_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            55512..56645
                     /locus_tag="NOB46_000202"
     CDS             55512..56645
                     /locus_tag="NOB46_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HCI1057183.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNVLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            56676..56966
                     /locus_tag="NOB46_000203"
     CDS             56676..56966
                     /locus_tag="NOB46_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HCI1057184.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKQ"
     gene            complement(57026..57485)
                     /locus_tag="NOB46_000204"
                     /pseudo
     CDS             complement(57026..57485)
                     /locus_tag="NOB46_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(57615..58868)
                     /locus_tag="NOB46_000205"
     CDS             complement(57615..58868)
                     /locus_tag="NOB46_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1057185.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(58897..59214)
                     /locus_tag="NOB46_000206"
     CDS             complement(58897..59214)
                     /locus_tag="NOB46_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI1057186.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(59240..59560)
                     /locus_tag="NOB46_000207"
     CDS             complement(59240..59560)
                     /locus_tag="NOB46_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1057187.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(60025..61440)
                     /locus_tag="NOB46_000208"
     CDS             complement(60025..61440)
                     /locus_tag="NOB46_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1057188.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREHEERYMDEKGIVQDDYRIEF
                     IGQHLRYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(61456..62772)
                     /locus_tag="NOB46_000209"
     CDS             complement(61456..62772)
                     /locus_tag="NOB46_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1057189.1"
                     /translation="MRGSGMSFMDKLAKVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISYLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(62922..63620)
                     /locus_tag="NOB46_000210"
     CDS             complement(62922..63620)
                     /locus_tag="NOB46_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCI1057190.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNIA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNVLAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(63909..64869)
                     /locus_tag="NOB46_000211"
                     /pseudo
     CDS             complement(63909..64869)
                     /locus_tag="NOB46_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            complement(64983..65816)
                     /gene="msrA"
                     /locus_tag="NOB46_000212"
     CDS             complement(64983..65816)
                     /gene="msrA"
                     /locus_tag="NOB46_000212"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI1057191.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(66050..66793)
                     /gene="truA"
                     /locus_tag="NOB46_000213"
     CDS             complement(66050..66793)
                     /gene="truA"
                     /locus_tag="NOB46_000213"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI1057192.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            complement(66984..67619)
                     /locus_tag="NOB46_000214"
     CDS             complement(66984..67619)
                     /locus_tag="NOB46_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI1057193.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(67766..69007)
                     /gene="sstT"
                     /locus_tag="NOB46_000215"
     CDS             complement(67766..69007)
                     /gene="sstT"
                     /locus_tag="NOB46_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCI1057194.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            complement(69328..70005)
                     /locus_tag="NOB46_000216"
     CDS             complement(69328..70005)
                     /locus_tag="NOB46_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCI1057195.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKNVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            complement(70256..70798)
                     /locus_tag="NOB46_000217"
     CDS             complement(70256..70798)
                     /locus_tag="NOB46_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI1057196.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(70803..71030)
                     /locus_tag="NOB46_000218"
     CDS             complement(70803..71030)
                     /locus_tag="NOB46_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI1057197.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(71109..72989)
                     /locus_tag="NOB46_000219"
     CDS             complement(71109..72989)
                     /locus_tag="NOB46_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI1057198.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            73275..73610
                     /locus_tag="NOB46_000220"
     CDS             73275..73610
                     /locus_tag="NOB46_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1057199.1"
                     /translation="MGIEAVDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLK
                     LLIHTACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECF
                     FIYDIIASK"
BASE COUNT        21784 a        15598 c        12352 g        24015 t
ORIGIN      
        1 catgtcctat ccttattaga atacaaagat attgttttcc tgacaggtac cgtttcataa
       61 gcacaccaaa taaactttgt ttattggcta ttcgacttac tgattagata ccagctacac
      121 tcacaaaaca taccccattc ttctaggtct tatttatttt ccacttaact atagcaagac
      181 acattttggt tgtcaaactt tagtatgttt tatagattta caccattaat gaatagacac
      241 ctaccgcgat aattgctccg atcattggac ctgcgattgg tacccatgaa tatgcccaat
      301 ctgaagttcc tttattagct attggcaata ccgcatgtgc taatcgagga ccaaagtccc
      361 gagcagggtt gattgcatat cctgttggcc ctcctaatga aagaccgatg gctaagatca
      421 atccacctac agcgaatacg ttcgttccag gtgcaaattc gttttgtcca aaagctagca
      481 acccaagaac taatacaaat gtaccaatta attctgtgat cacatttgct ggataattcc
      541 gtatagcagg acctgttgca aacgttccta aaatcgcgct ttcatctttc gttgcattcc
      601 aatgtggcaa ataagaaagc caaacaagaa tggcccctgc aaaagctcct aaaacttgcg
      661 caatgatgaa aggaacgaca agattccaac taattgcccc tgtcatcgcc atagctagag
      721 agactgcagg attcaaatga gctgggccca tgaatccaga aatatagaca gccattgtta
      781 cagcgagtcc ccaaccaaat gcgatgacaa tccagccaga agcctgtgct ttacttttgt
      841 ttaaattcac agccgcacac acaccatctc caagcaaaac taggatcagt gtcccaataa
      901 actcccccat gatttgagtc atatcactgt tcatttattt ctcccccttt agttcccgca
      961 gatctgattc tgcaatcaat gcttctaaac gtttagtctg ttgcgccttc tcctcttctg
     1021 tccattcaaa atatccagca attgcatcga tcacaggttg cttgatctca tcaagctgat
     1081 ctcgttcaaa caacagatga tttgtacgac gaatgagata atcgcctggg gccaaaacca
     1141 tttcttcttc taaaccataa cgtaaccgag ctgactcagc gagactcaaa ccaggataag
     1201 gtgccatttc ttttgctaat tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga
     1261 tataagtagc atcttcttcc tctaaaccgg ctgctactcc ttcttttgct aattctgtca
     1321 ctgtttcttc taatttagtt ggatcgaagt ttccacctga aatctgatat tttttagagt
     1381 cgatttcttt cgtctctatt ccgtattctt cttttaataa ttggcgtatc aatcgcaaag
     1441 ctccttctgc catcttacgg taatcggtga ttttcccacc agataaagtc agcaaaccat
     1501 ctggttctct ttctaaagaa ctacctctgg aaatcgtaga aggtgctttt tcatcacggc
     1561 tgttttccaa atggttcaac acgtcttcta cttcagcacg agaaactttg ttttccttat
     1621 attcacttac tgtatcgaca actttattga agctcttgtc tgaaatcgat ccattatctc
     1681 caccattgta atcagaacca gaattaccaa tcaacagtgg acgaagtcct gcccagcttg
     1741 cttcgatatc attcaatgtg atatttgctt ctggatagcg atgattgatc acatccaata
     1801 gataatctac atcttcttgt gtgactttcg gatccgtaaa atctccttgg taatccgtat
     1861 ctgtcgtacc aaagtaagtc ttgttttctc ttggaatagc aaaaaccatc cgcccatctt
     1921 gctttcctgt atcgaagtat gtgggttgcg gtacaggcag ttttttcgca tctacaacta
     1981 aatggatccc tttagttgga cgcattttag gagagactgg acgcgtaaaa ttcaagtttc
     2041 gtactttatc tacccaagga ccactcgtat tgatcactaa ttttgctttg atttcgatca
     2101 cttcatctgt cagcaggtca cgagctttga cgccaacgat ttgatcgcca tcatataaaa
     2161 agccaaccgc tttcatttta cttactagat aagccccatc ttcggcagcc tttttgatat
     2221 tatcaatcac taaacgggca tcattgttgc ggaaatctag atagacaccc gcgcctttta
     2281 gcccttcttt tttcaaaaac ggttctcttt ccaatacttc ttctggtgtc agcgtataat
     2341 tctcatattt ggttcctgtc acatttgcca gtttgtcata aaggtccatt gctactttga
     2401 ccgagaacat attgaaggtt gttgctcctt cgccctcata gattggcaaa agcattggat
     2461 ctggttttgg gatgtgtggg gcaatacttt gtacgactgc acgttcacca actgtgtcag
     2521 ctactacttc cacatcaaat gtcttcagat aacgaatacc gccatgaaca agtttggtcg
     2581 agcgagagga agtcccttct gcaaaatcct gcatttcgat caatcctgtt ttgattcctg
     2641 atgctgctga ctggactgcc acaccggcac cagtgattcc gccaccgatg atcaacagat
     2701 ccaattcttc ttgctgcatt ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat
     2761 ggatttcctc cttattcaaa tgcttgggta gcttttactg cttttttcca accgttgtaa
     2821 agtttttctc ggcgctcttc ctccatttga acttcaaata gcttgccagc ttcataaaat
     2881 tcgcggatct cgtctgtatc tttccaataa ccgacagcta atcctgctaa aaatgctgcc
     2941 cctagcgccg ttgtttccaa gttttctgct cgttggatcg gtacattcaa gatatctgtt
     3001 tggaattgca tcagatattc attgtttgct gcaccgccat ctactttcaa tacaggaatc
     3061 ttgattccag tgtcatcttg catcgtatcg atgatatctc tcacttgata agcaatcgac
     3121 tgtaaagtag ctttaatgat atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc
     3181 cctcgtgctg cctgatccca ataaggagca cctagcccaa cgaatgcagg aacaacataa
     3241 acctcatctt cgcttgtaga gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac
     3301 atttgaagtc catctctcag ccattgaatc gaagaaccag ccacaaaaat acttccttct
     3361 aaagcatagt aaacctttcc atttatgccg taaccaattg tcgtcaataa attatttttg
     3421 gataattgcg gtttttcacc ggtattcatg acaataaatg aacctgtacc ataagtattc
     3481 ttgaccatgc ctggttcgaa tgccatttgt ccgaataatg cggcttgctg gtctcctgcc
     3541 atccctgaaa ttggtgcttc gcttccataa aaatgataac cttgcgtata accataaact
     3601 tctgagttag aagtgacttt tggtaacatc actcgaggaa tatttagtaa atctaaaatc
     3661 tcctgatccc aatctagctg atggatattg aacaacatcg tccgactggc attcgagtaa
     3721 tcagtaacat gtgcttgtcc atcggtcagt ttccatacta accaagaatc gatcgttcca
     3781 aacatcaatt cgcctttttc agctcgttct tgcgcgcctt ctacatgatc aagaatccag
     3841 cgtatcttcg ttgctgagaa ataggcatcg atcactaacc ctgttttttc gtggaaaaat
     3901 tcttgatagc cttcattttt taagttatct gcaattccag ctgactgtct ggattgccaa
     3961 acaactgcat gatagattgg acgtcctgta tctttttccc atattactgt tgtttcacgc
     4021 tggttcgtta tgccaatccc agcaatctga tttggtttga tccctgattc gatgaacgct
     4081 ccggcaataa ctgactgtac agaattccag atttcatttg catcatgttc cacccaactt
     4141 tcttgcggga aatattgcgt gaactctttt tgagaactgc cgatgtgtct tcctttcttg
     4201 tcaaagataa ttgctcgtga gctagttgta ccttggtcaa tcgccatgat atacgttgat
     4261 tctgtcattg tgattccctc cattatatgc aaacgctttc tttaactact cttatcatac
     4321 tactgtttta aaaaaagaaa ctgtcaaaat tttattcttt ttttcttttt ttgacagttt
     4381 tttattatga agctattttt taatcaattc ttttcttttt tcagcgtctc tattcttctt
     4441 ttcaatcgaa taatgtcgta aggtgacgca aattctgaca gataatattc acactgtttt
     4501 ttgtttctct ggcaaaatgt gatcaccaaa tcatattctt taccttcttc ataacttcca
     4561 atctcaatac cgccgattcc cctcagttct ctgatcagat attgttgaaa agcaatacga
     4621 taaatcggca gactttctaa atcgattcca atcactactg gttttgcaat ataaaaatcg
     4681 atcatcaaaa gaacattggc atactggatc atcaggtaac taagctcact atcttcagct
     4741 cttttcctcg gcaattgctg caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag
     4801 gaatgcccga gcattttctg ctgctgttcc aaaagccgat cacgctcata gacttcgatc
     4861 tttccaacaa agaaaaacca ttcattgttg atctgggaaa tttggtagcc tactgccttt
     4921 tcttctttga ttttcaaacg acgaggacga taatgccata acatcgtttc ccgaatgtaa
     4981 gtatctaaaa cagcggttgg taactttttg ctccgtgtca aatcatactg ataaaatatt
     5041 tcttcgtcta ctatcgaaaa agaaacaaaa aagctgtaaa acatcattgt ttcgtataca
     5101 ttcagttctg ctgctgttcg actaagatgc atcacgatga ttggatcgat tgcttgataa
     5161 agccggtccg actgatagag taatttcttt tctttcaaag ttgcgtacgt acttttttca
     5221 ttcaatagtc tttttttcgt aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc
     5281 gtaaacgttg tttctaatac acggtccaat cctagaatga acggtctttt ttctggtgta
     5341 ttttgcaaaa aaagcggtcg ctgatcttcc gggatatatt ggaatagttc ataataaaaa
     5401 tatcgtatct gtagctcttc tccgtataat tgaccgtttt tgatttgtaa tccaaattcc
     5461 tctaagagct ggttcaattc tttgatcttt cgaaaaacag aagactcact gatattaaac
     5521 gctgtcgcta atcgaacgat ggatacttgc tgatgttcta ataaatagac gagcatctta
     5581 aacttcaagc tttcctgcaa taaaaacaat agaatttttt ccaaacttac atcttcgtcc
     5641 aacacaagca gcgcctgata ctcatttcgc tgtacttcta cttttttttc catcattcgg
     5701 ccaatcaatt caatatcttc caaatattga tcaaacgagg cttttgacag ttggacatgc
     5761 tctctcaaac cattgataga ggctgttccc ccttgcagaa caaggtttcg caaaatcagg
     5821 atctgtaact gctcttttct ttctaataat gcttcaatct tcataggcag tattcgccac
     5881 ctttgaccac accatatctg gcacacggta ttctggctgg aaaaatagct catgttcttc
     5941 taactgttca aacgtccatc cttcttctac tgcaattgtc agttggtcaa gaaggtggaa
     6001 catctctttt ttgctttgga gctgtgctcc aagaatcttt ttttcagaat caaatagaaa
     6061 tttgagttta actttgcttt gatttattgc tgtaagcttg tagtctacgt atcctgtttc
     6121 aattttttgg ggataaaaaa tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata
     6181 gccaaaccac tgattgccga ctggacgata ggttccctga tcctttgtct gtgagccact
     6241 aattgtcttg ctgacatttc gtgctgtacg gacagcgtta tttactagag aaacatacat
     6301 tttttcattt gttggacgaa aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt
     6361 ttgagacgtt tgcaagtagt catctaccca gatcgttcca tcatcattca atgttaattg
     6421 ttcttcccac atctgattgt cgggacgaga atgattagcc agcaaaacaa gatcatagtt
     6481 ctcctttctt ttttccgtct ctacaatagc ggtttcattt tcggtcaaag acacaacttg
     6541 ttcttctaaa aaaagtgaaa gcccttgatt tttcatttcc tttactaacg gttctgtcat
     6601 ttcaggatct agataacgaa aaagaattga ctttcggctt tcgtaaagat ggatttgttt
     6661 ttttcttgat gccaaccctt cagctatttc gattcctgct tgtcctgcac caataattgc
     6721 aattttcttt gcattcatga tcttttgctg aagagccgtt acgttttgta tctttttaac
     6781 tgggtgaata agcgttgatt ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc
     6841 tagaatcaaa cgatcaaaat ccaatttttt tcctcctgct aaaacgactt ttttttcttt
     6901 caatcctatt actgtctttt ctgtgtaaac atggattcga tagcggtcag tcagttcttc
     6961 tttcgtgatc caagaaagtt gtttttcact ggtaaccttt ccttttaata tcaaattgaa
     7021 cccgctggga atccatccta acttcgattg cttttcaatc aaatatattt cacttgttgg
     7081 catcaattgg cgaagataaa tagccgcatg aatccctgca aacgacccgc cgacaattac
     7141 aatgttcatc tgcattcctc tttcttataa ggtgttctac tgctaacttc tcaatcagaa
     7201 aacacagtat tcataactcg ctttcaacct tatgatacat agcgatgcag cagaatcaac
     7261 cctctccatc ataccgtgtt ctaggtctgc ttctcaataa tgtactagtg gacctaattg
     7321 aagagtatca tttctgaaga gatgtttcaa aaaatgtact cttataaaag aaaaaaactc
     7381 gccttttacg tacctctgtc caaataggaa acagaaaaga acgaaaagac gagttttagc
     7441 gtgtgtaatg taatagttag aatagacaca tcatttattt ttaattcttt aatgcttcaa
     7501 caactgcttc gcctaattga tgagcagatt gaggattttg ccctgtaaga agccgcccat
     7561 caatttgaac cacttctgaa aaagctgctc cagactgata gtttgctcct ttttctttca
     7621 aagcatcttc tgctaagaat ggtacttcat tcgttgtacc atttgcttcc tcttcttcat
     7681 tactgaaccc agtcactgta cgtccagcta aaatagattt tccagactca tctgtaactg
     7741 gcaacaatcc tacaacaccg tgacaaacag ctgagaccag cccttcattt cgatagattt
     7801 gtgaagcgac tttcccaaga tctattgctt ctggaaaatc ccacattgtt ccgtggccac
     7861 cagcataata aaccgctgca taatcatttg catccacatc atcaggacgt aaggtatttc
     7921 ccaaggcccg atttctgaaa tcttcatctt cataataggc ccaatcgatt tcatccatat
     7981 tcaaaacact ttgcggttct aaaggtacat atccgccttt aggactgaca aaatctgcat
     8041 cgatcccatt ttttactaat acatcataaa aatgagtcag ttcacttaac cacaaacctg
     8101 taggacgctc gatcttttcg tacttttcta catttgttaa tacgatcaat actttcattt
     8161 tcccatcctc tttctataaa aattgcgtta ttgataacgt gctttcaaga aattatataa
     8221 tgggcttggc aaataaagct ctttatatgc ttcttcaaaa ggtttcgtta caaattcatc
     8281 ctcacggttt tccaataatt tctctgccca gtcaggatcg acgatcattt gctgtccaat
     8341 tgctgcaagt tctgcatatt tcaatacctg ctctacatct tcgcgattgc ggatcccacc
     8401 gacaccaact aaagggatct ttccttgaat cgtgttatgg accacttcaa gaatcgattt
     8461 atcgttgtat ttatcagaac gagctattcg atcatacata tttaatgaaa catgcagata
     8521 atctagtttt gactcacgta atcgttcaag aagccagatc gtgtcttcaa aacggatacc
     8581 tggtgtttca tattcttctg gtgagaaacg ataccctacg atgaatggtt ttttagcata
     8641 ttgttcaacc gctgagaaaa ccgttgttaa taattcttca ataaaacgat aacgattttc
     8701 caagctaccg ccccattgat cctctcgtct attcgaatgc ggagagaaaa attgttggat
     8761 caaatacgta tttgctccat gcaactcgat tccatcaaat cctgattcaa tcgctctacg
     8821 tgtggctttg ccaaatgctt ggattgtttc aacgatttct tcttcactca ttgctcgtgg
     8881 tgtttccgca tcaggacgtt ttgctgcaac tgcacttgca gatacaggct gttctccaga
     8941 taaagttgct cgacttgtca ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc
     9001 ttctccttgg attgctttcg ctagctcact taatcgagga atcatttcat catgagcgat
     9061 gctgagttca cctggccagc cttttccgat atcttggaca tttgcagcac cagtaataac
     9121 agcaccaaga cctttagaac gttgtttata ataagtgatc tcatcttcgg tgatcactcc
     9181 attgaaaaag ctgagttgtg tcgtcatagg cgacagcatc aatcggttct tcaattgaac
     9241 tcctgaaggt aaagtaattg attgatcaaa ttgtgacatt gtcattcctc ccataattcg
     9301 ctctgattaa cctatcgaga atcatctatc attaaaccac tcgattagtt gtacatgcaa
     9361 ctaatttgct taaaaaattt tatttttttt gtaacttatc tgttgcatca ttcattgtct
     9421 gggctaattc tttacttgct tcatttccca aaactgcttt gtatgactga tgaagttctt
     9481 cccagctacc atcgacttcc ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg
     9541 acaagcgacc ttcgctaact gttttgacgt atcctttata ttctaatttt tcaacaaaac
     9601 gagcaatcgt tgatggggcg gaatagagca tttgtgcaat atctttttgt ggtattccat
     9661 ctttttcttt taatatcaat aaaataaaac cataagttgg tgccagacct gtccttctaa
     9721 acgcttcatc agctaattta ttcaacatgc gatctagctt tttcacgcta aagaaaagac
     9781 attcatctaa cgctttttca attggctttt ccatttcatc ccctccattg gcgtacatat
     9841 catagtatga tttttatttt ttgtcaaaaa acacggaata atgtccgcct cctctgtcta
     9901 gatttgaaaa aaagaagtag ccatcttcaa agaatttcgg cttgttttcg acaaaactcc
     9961 ttctggaaca ccgtgaatca gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa
    10021 aattttgtga aaatggcttt ccacattttt gcataaattt ggcttaatac cgaaaaactg
    10081 gcttttgaac accgtttata tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag
    10141 aacagccaaa caaaaatagt tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc
    10201 agctgattgt acaccgttta ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa
    10261 ggagcaattt caaaaaacag cttctcatgt tttatgacta tggtgacttg tgatcgagga
    10321 gttggcagga gaatactgtt tattcgtaaa gaaggggctg tgacaagact tttgtcacag
    10381 tcccttattt ccttttatta taggatttcg ccatttgatt ggatgacttg tctgtaccaa
    10441 tcaaatgatt ttttctttaa ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca
    10501 tagatatatc cataacgttt tgacatttgt gaagtagaag cgctgacgat atcaatgcag
    10561 ccccacgacg tataaccaaa taaatctact ccatctttga tagcttcctt catctgctca
    10621 atatgctgct tcaaatagtc aatgcggtaa tcgtcttgaa cggttccatc ttcttctact
    10681 ttgtctatag ctccgagtcc gttttcagct atgaacagtg gtttttgata cctatcatat
    10741 aattgattca aagcaattct caaaccctta ggatcaatct gccagcccca ttcacttgat
    10801 ggaagatacg gatttttaat tcctccagtt attaagtttc cttggacccc ttcccaattt
    10861 tctggatgag cactgactgc actagacatg tagtagctaa aagaaacaaa atcaacaggg
    10921 taggctgcta agatttcttc atcacctact tctattttta agttgacacc tttttcttca
    10981 aacattcgtt gcgtatacgc tggataatat cctcttgctt gaacatcact aaagaacaaa
    11041 gaagttcttt gctgctcaat tgttttttga atatcatccg gatcacaaga atacggaaca
    11101 agaagctgat agctgatcat acaaccgact tgtgaacctt tgataatttc atgacaagct
    11161 tttgtagcta aagcacttgc tataaactga tggtgtgcac cttggtattt cgcttgttcc
    11221 aaatggggat ggttttcttc aattactcct acgctaacaa aagggtgatg ttttacacag
    11281 ttgatctcat tgaaagtcat ccaatatttt actttatttt tatagcgttt gaatactgtt
    11341 tcagcgaaac gaacgtaaaa ctgaataagc tttcgattag gccatccacc atattctgta
    11401 accaaatata acggcatttc ataatgggaa agagaaacga ctggctcaat cccatatttt
    11461 agacattcgt caaacacttg atcataaaaa aataatcccg cttcattggg tgtttcttca
    11521 tcaccatgag gaaaaattct tgtccatgcg atagacatcc gatagcattt aaaacccatt
    11581 tcagcaaata aacggatgtc ttctttaaag tgatgataga aatcatttcc gtgtctttta
    11641 ggataataat acttgctgtt gggatcctgc gccgctttta cttgctgatg cgtcatcata
    11701 tgccattgat ctgtccattt ttctttaggt aaatcgctgt cgaatgtata cacatcagac
    11761 acagataatc ctttttcatc tacatcccat gcaccttcac attgattggc cgctgtcgct
    11821 ccgccccata aaaatccttc tggaaatttt ttcatatcga tccccctaaa cttgctagtt
    11881 ttcttgtttg attatttttc ttatgactag taatgatatt tttgaatcta ctactatttg
    11941 taacaataac cattgtggtc ggatcatatc cctctttgat taattcttgc aaatctactt
    12001 ccatcaataa atcgccttta cgtacttttt ttccatcaga tactgcactt tgaaagtatt
    12061 tgccatttaa attcactgta tcaataccga tatggatcag tatctctgct ccttcttcac
    12121 tgactacccc aattgcatgt ttcgttggaa aaactgttga aacttccccg tttacagaac
    12181 tgtagatttt tccgtccgtt ggaatgatcg caaacccttc tcctaaagat ccactagcaa
    12241 atgttggatc gtttacttca gataaatcaa ttatttcacc tgctgcagga gtacttaaca
    12301 ctatatcctt tgaggattct tcttcgattt catccttgta gccgaaaaga aaagttagca
    12361 tacaggaact gatcatcgct aagaaataac tagcaactag ccaaacaaat ccttcaccaa
    12421 tataaatcgg gaaagacaaa atacttcttg tagcaactgc caaagcaccg gctcctgcgg
    12481 caccagctac tccaccaaat atagctccac atatacaagc aatgtaaaat ggtcgtttat
    12541 atttaagagt cacaccataa acagcaggtt cagtgattcc aaataatgct gtgataaatg
    12601 cagataaaga taaacttttt actttcttat ttttcgtttt caaaaatacc ccaagtactg
    12661 ctcctgcttg cgcagctacg gcagtcatac atgctggacc tagcgtatca cgaccgtaga
    12721 aagaaagatt gttggtcatt actggtacaa gtccccaatg taacccaaaa atcactaaca
    12781 cttgccaaaa tccgccgata acagcaccag ataaaacagg gctaaagtta taaacagcta
    12841 aatatccagc tgcaatcagc tgacttgcat aatctgcaat tggacctaca actaataaaa
    12901 taattgggac catcacgatg atacaaatga atggtgtcaa taaatttcga atactttcgt
    12961 gcaagctttt gcgaatctta ggctcaatat aagaaagaac ccatacagct aaaattgctg
    13021 gaataaccgt acttgtatac cttgctagaa tcacgggcat ccctagaaat cgcaaggtta
    13081 tgctatcact atatgcactg acaatcgtag gataaacgag agctgctgca ataaccatag
    13141 cgatgaaacg atctgtattg aacttttttg cagcagtata tgccaaaaat ataggcaaga
    13201 aatagaaaaa tgcatcagct gctgcattca aaatgatata agttcctgat tcagtagtta
    13261 ataaattcaa actcgtacat aaggcgagta ctcctttgat caaaccactt cctgccaaga
    13321 cgcctaaagt cggggcaaaa acagcggcga tcatgtctat aaaagagttt aaaatgcctt
    13381 ttttctcagt tcctctcttt ccactagatg catcatcttc tagtttcatt tgtttggata
    13441 atacgtcata cacttcattt actgcatttc ctactacgac ttgaaacatt cctccagctt
    13501 cgactacagt gatcacacct tctagttgct ctaccttctc cttatctgcc ttcttattat
    13561 cttttagggt aaagcgtaac cttgttgcac aatggtaaac attgctgaca ttttcttcgc
    13621 ctccgacaaa tcggacaata tctttcgcta attgtgaata gtccattttt acttccccct
    13681 tgttaattaa tgccgtagca atccttctta caagataagt atagttctta gaaaacggtt
    13741 tctccattca attagtaccc cttctaatag cgaacgaaac tgtacaatag tgtgtatggt
    13801 ttacttagcc gagcaaatca ctcactgctt gaaagaaaac aagtatatcg tttctcttat
    13861 agtcaaagga gacaaaaaaa acacgcttga tcttcctttg ctgatgtata agtggtatct
    13921 caagctgata ctctgtgatt tttgtttcta cttggctttt gataagacag cacaacaaag
    13981 tctcggcatt taacggaagc ataactaggt cagaactagg agagattagt tgctgaatgg
    14041 aatctatctt tttatggatt tttatttgat tttcttcttt gtagtaatga tcaagcagtt
    14101 ttgttttctt tttttcttca actatggtca gcttttcacg caaaatctga taaatctccc
    14161 aagattcaaa ctcatctaga acactaggta gataaatcaa atcatcccac tcaaaaataa
    14221 gctcttgctc agtagtcaaa attgcatcat attccgttat tttgtttgat tgatttttga
    14281 aaagatacac tggttctatc cggcattctt tgatccacat gttcatactt tgttgaatct
    14341 gtttttttag tgtattcaaa atactaattg gctggttact aacaatcagt atctcccctt
    14401 gttttcgaaa aggattcaac gcttcggcaa gatacaaaac aaaataagcg ctttcagcta
    14461 aattgggacg taattgaaaa tgtattggga agaaacgccg aattaaataa atttctaaag
    14521 gataacggga gatgatcttt tgtacaaaat gattcatggt attatgtccg gcatccatcc
    14581 tcgttttcat ttgtttgata tgggttagca aaaattctgt ttcatggaac aataacgaaa
    14641 caggaagatc taaaaaacga ataatcgttt gctcaaatgc tcttagattc ttctctattt
    14701 ctttgttttt ttcatcatta atcatcaaat aatttaactc taatagtcga ttttcaattg
    14761 cttgtttttc ttgattggaa aaagaatagg gtagttctga tgataacttt tttgtgaggg
    14821 tctctaccat cggaataaat aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc
    14881 gaagaatggt caaaacgaga taccgagaaa atcgtatgaa gtcctctcct gaaacaatat
    14941 aattatatga tataagaacc tcttttaatg tcttttggac agtcggcatg atattggaaa
    15001 aaattgtact gatttgttga ggaaaccttg cgtgttggat caccgtttct gttccaacaa
    15061 gagataagaa aattcttttt gaattttctt cagcaatgat ttttagtcct tttgtcgacg
    15121 aaacttccag ttctaattta ggattgcgct cgatccaacg caaaatcgtt tttatttgta
    15181 atgatacggc tgtttttgaa agaaagaaaa tgtctgctat cttttgcata ctgacatacc
    15241 ctttttgaaa caataagtac gtcacaatag ttgaagctcg gaaatccatg ctggaataga
    15301 ttttatgttt cgtcacctct tgtatgattt gctgtttagt ttcagattca attgattcta
    15361 aaaaataacc tgaacgttta tttgactgga taatgatttt cttctcgtag atagcaagca
    15421 tatttttgat ttcagtttgg atcgttttct tgttggtacc taaagcttca gctaattctt
    15481 cgcttgttat ccaatgattc ttatttctta atactacaag aatttggagt tgtcgtttat
    15541 ttaagtccat ttgcttacac ctcctctttg ttataaacat acaggaaaaa cctctcaaat
    15601 gacaatagtc acttgcagag gtttaaaaat catttgaaga aagatctata ttcaaggttt
    15661 ttaccattag actggataat ttgtttataa tattcaaaac tatctttttt caatctccta
    15721 aagcttccgc tcccatcatt ttgtctatcc acataaataa agccatatcg cttcctcatt
    15781 tcccctgttc ctgccgatac gatatcgatt ggtccccacc ataagtaacc aatgatttgg
    15841 caaccatctt ttattgcctc agcaatttcc tgaagatgta tttttagata ctcacaacgt
    15901 tttggatcgt ggattcgatt caattcatct ggtgcttcat ctagtccaat gccattttca
    15961 actatgaata atggtaattc ataacggtct gtcaattcat tcatgacata acgaaaccct
    16021 agaggatcaa ttggccaact ccaaggttcg ggagattttt ccttcaaaaa gggattatcg
    16081 aaaccatttg ctccgccagt atctacgcgc atttctgctt cttttttata gacagcgcta
    16141 cgataataac taaatgcaat ataatctgcc gtgttagctt gcaagcactg ttcgtctcca
    16201 tctaacatta ctggtgcaca gtcttcttcc ttccatgtcc tgtaaatata agctggataa
    16261 tgccctcggc acatgacatc ggagaaaaac catgaattgc gtttaaattg cagtgaacca
    16321 aatacattct ctggatcaca gtcatatgca taagtcgcta atgcagaaaa gctacacata
    16381 atacccatct tagcatttgg atcgattttc tttaataatt gagtagcacg ggcgttcgct
    16441 agaaacatat gatgacaggc ttgataaatc actttttttg ttagtgtagc aatgggttca
    16501 agtttatctc tagcagggaa tgtaaccaat ccagcagctg cataaggcat acgaaaagca
    16561 ttattgatct cattaaaggt catccaatat ttcactttcc cttggtagcg ttcaaagacg
    16621 gtctgcgcat aaaattcaaa aaagtcgatt aattttcgat tttgccaccc cccatactct
    16681 cctaccaatg ctaagggggt ttcataatga ctaagagtaa ttactggctc gatatcatat
    16741 cgatttaatg tattgattag tctgtcataa aatacgagac cagcctcatt tggcttctgt
    16801 tcgtctcctc ttggaaatat tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct
    16861 aactccttca gtaaacgaat atcctcttca aatcgatgat aaaaatcaat cgcttcatga
    16921 gaaagataat ggagtgattc gtctaaagca atctcccaaa tctttttttc ttcattccac
    16981 tgaatactag gatgctggtt catgatcccg ataagcgtat ctgtcacatt aggtaatttg
    17041 ccgtcttcca accatgcacc ttcacattga ttagcagcta ctgctccgcc ccataaaaaa
    17101 ttttctggaa atatttcctg atccataact atctctcctc gctatcaaca atttcttact
    17161 tgaagtatag ctcgattcat caaaacaaga tattctaact atttcggcag aagagaagaa
    17221 aaaaattgaa tgctactctt catttttaat atttatatat aacaaataca taagacgatc
    17281 cccgaaagaa aacactcgtt aaccatctaa gcaaacgatt tattttactt ccaacacaaa
    17341 tgcttcataa ggtcgtaaat caactttgcc gtctggtaac tgtttcagag gataatttga
    17401 cacaataacc cttaaagctt cacgtggaat agtgaacgtc tgcttttcac tggacatatt
    17461 acaaataacg agccattgct ggtcttcata tatgcgagaa taggcaaaga catgctcagg
    17521 cgtcttttcc actaattcat agtctcccca gacgatgatg tcatgttttc tacgcaaatc
    17581 gatcaatttc ttgtacatat aaaaaacaga atcttgatct gctaacgctt cttctgcatt
    17641 gatttcttta taatttggat tgactcgaag ccatggaatt ccagtagtaa acccagcatg
    17701 ttcacgggcg ttccattgca taggcgtcct agcattgtct cttcctttcg ccttgattga
    17761 ttccaagatt tcctcttttg taaatccaga agaaatcctt tcgttataca tattgattgt
    17821 ctcaatatct tttgcttccg cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc
    17881 tccttgatag atataagggg tgcctttcat catatggagc aagatagcaa acatcttggc
    17941 actttctttt cgatacacat cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg
    18001 attattccaa aataaactat tccatccttc atcacctaaa gatgtttgcc atttggataa
    18061 tacttttttc agttcagaga tactcaaggg tttcaaatcc catttgtctt tgccttcttg
    18121 ctgatctaat cctatgtgtt cgaattggaa gaccatggat aattcatttc ttttaggatt
    18181 ggaataaagt ttagcgattt cggtagttgc tccccatgtt tcgccaacag tcatcagatt
    18241 tttgtcacca aaagttgctt gattcatttc ctgaagatac tcatgcagtt taggtccatt
    18301 acttgtgatt tctttatccg gttctttgcc aatcatatcg atcacgtcca tacgaaagcc
    18361 cccaatacct ttatcgatcc agaaattcat catttgataa atctcttggc gaacctgttt
    18421 atttttccaa ttcaaatcag gttgacgctt gctatacaag tgcagaaaat attgccccgt
    18481 tttttcatcc aactgccaag cagaaccact gaatattgag cgcaatctat taggctcttt
    18541 tccattgacc ggatcacgcc aaatataata gtcccgataa ggattttctt tatttttacg
    18601 ggcctcaatg aaccacggat gttcatcaga agtatgattc accaccagat ccatgatgat
    18661 acggatattt cttttctttg cttcttcaat cagttcttcc atttcttcca tcgtaccgaa
    18721 ttctgccatg attgcttgat aattactgat atcataccca ttgtcatcat tcggagactc
    18781 gtatactgga gaaagccaaa ttgcatcaat acctaaatac gccagataat ccaacctgga
    18841 aataatcccc cgcaaatctc caataccatc ttgatttgaa tcttgaaaac ttcttggata
    18901 gatttgataa acaactgaat ggtgccacca tttttgttcc atgattttcc tcctataaat
    18961 ggatgtttct attttttgct taatcattta ttttagtctc tctcactaaa aattgtaacg
    19021 ctttcaaata gctattgcac cttgttatcg gtaacagaat aaaacaaaaa aacagctgag
    19081 gaaattccct caactgtttt ttgaaaggat tgatttatgc agggaagaat gctgatttca
    19141 caacttcttt ataaacggtg ttcactcagc tgtcccttgg tattagctca aaaaacggca
    19201 aaatataaga aactattttt tcgttttttt ctctaatact caggccagaa cgctgatttc
    19261 acaacctctt tatttcacat tcaatatcca catgaatccc acaaatacaa agaacagacc
    19321 atacatgatt ggagatactt cttttcctct tttagctgct aacatggtaa ttggatagaa
    19381 gataaaacct aatgcaatcc catctgaaat actataagtc aaaggcatgc cgatcaagat
    19441 caagaatgaa gggatcgcaa tctctaagtt tccccattcg atttgtcgca aagattgtgc
    19501 catcaatact cctaccataa tcaatgctgg tgcagttact tgtgaagtaa caactgatag
    19561 taatggagaa aagaacaagc ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc
    19621 tgaacgtcct ccaacggcga taccagctga tgattctaca aatgcaccaa caggagaagt
    19681 accaaataag gaacccgcaa gcatagctgt tgaatcagaa gctaaagctt tccctacacg
    19741 aggcatcttg ttgtctttca tgaaacctgc ttggtttgct aatccaacta aagttcctgc
    19801 tgtatcaaag aaagtcacaa gcaagaatgt cagcactacg acccacattt gaagagaatt
    19861 gatgtcccct acatgtttta atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc
    19921 aacaatttca gaaggcattg gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc
    19981 catcccgatg aagatgccac ctggtacacg ccgaacaagc aagatagcag ttacgactaa
    20041 tccaaaaatc gtcaaccaag tagaaccaac gttgagtgat cctaatccta ctaatgtaga
    20101 ttcattcgaa acgatgatcc caccttcgct cagaccaagg aaagcgataa atagaccgat
    20161 accgccagaa atcgcatatt tcaaatctgc tgggatcgca tcaatgatca tttcccgcag
    20221 cttgaagatt gtgatcaaaa taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt
    20281 ttcccatgga atccccattc ctaaacaaac agaataagca aaaaaagcat tgatcccaag
    20341 agcaggtgcc gttccaattg gataacgggc taataccccc attaaaatac agccgatcgc
    20401 actggctaat gcagtcgcag taaacactgc tccttcatcc attccagaag cacctaatac
    20461 agttggattt acaaataaga tataagccat tgagataaat gttgtaaatc ctgccagtac
    20521 ctcacgtttt accgtggtgt tcaatttttc tatttcgaag taggaaagta ttttttcctt
    20581 catcttccat ccccctaaat ccgaacatta taaataaagt ccgttaaaat ttcgatttat
    20641 taataaaaca acgtgtttta tcatatacta aaacaaaata taagtaaaca aaaaattcgg
    20701 attttaagca aaatccgaac gtttcatctg attaaatccc tttatctcaa agttcatgaa
    20761 cattcacttt ggattacaag aatttcttta ttgtgttaat aaagtttctt cattctagtc
    20821 tcaaaaatca atagtgtgat ttgattttac catttcgttt ctgttattct ttgatgaatt
    20881 cttttgtatc gacaggattc agattattta gtccgccaaa acctgtgtcg accatttttc
    20941 cccagccttt tgtcttcttt tttcctgatt tgagattctt tgctcgaagc ttctcactat
    21001 gttttgctcg ccgatacttc aaataacctt ctaatcttcc cattagatcc actgtttttc
    21061 ctccttttta ttcaatcaga cgactcagct tttcctataa caaaataatt gccttcaggg
    21121 tccgaaaaat tgaaagtcaa gacgccattg ttgtctgtga tttctcctgg ttcttccatg
    21181 ttctcgtaga tagtctcaaa ttcgtccgta aaaaacacta aagaaggcgg tggtcctaat
    21241 acttctggtg aaaatttctg cacaaatact tttgggaata cgcctaattc taattctttt
    21301 gagatgctga gtacaatact cttaaattct tctggcaatt cgattgtttc agaaatttct
    21361 gcaccaattt tttctacaaa gaatcggcaa atcatctcta cgtcattgac ataaagcatc
    21421 acacgtgttt tttgtatcat cgtttgaccc ttctttctat ttgattttct ttcctgtcta
    21481 taaactgatt ccattatatc acgaaagcgc aaacaccttg tgtttgatac tattcaagaa
    21541 aaataaagca atagtttcta ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa
    21601 aaacggcaat gaatgccgct cttctttttt cgattctttt ataattctgc ttctgattca
    21661 tctttggtta gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc
    21721 aacgcttcga ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc
    21781 agcaccgctg cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga
    21841 cagcgacaga tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca
    21901 tcggaatctg cacctaaagg caggaatgat tcgccacctt gggcttttcc taaatgcaga
    21961 tttcctgcga tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata
    22021 ctattataga tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt
    22081 ttcagtaaag cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc
    22141 tgacgccact gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt
    22201 gcttcttttg ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg
    22261 tggttatcga taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag
    22321 aaattggtat ccactattac ttttttcata tgttcacacc tcttgattag aataattgct
    22381 tgatgaatag atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt
    22441 tgataaatcc ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga
    22501 gccaaatggc tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg
    22561 taccgatacc ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat
    22621 gatcagccat ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct
    22681 cttgatcgat actcactagg aaaaaatcgg tttctttatc ttttagctct tctgtaagtt
    22741 tttctggcgc ataagcttgt gtcaagtaat cagctaaatg cttcggtgaa ttatcttttc
    22801 caaatgtatc tgtaaatgtt tcgatactga tttgttgtag taagtctaca tctgaaggcg
    22861 tcatttttcg aatttcgtat ttattcacgg cttcttcctt tcaatagatc cttttattgc
    22921 cttttttgac aaaattccaa tcttcgctaa cattcttgca tactttattt aaaagatatt
    22981 ccaattgttt tgcttcttcg tcagaaagac catttaatgc gactgcattg gagtagttgt
    23041 tttctcgaat gatgaaagga tagatttctg ctcctttttt agtcggatag agtttcttga
    23101 tttttttatt ttctttatct tccaaacgtt cgatcatccc attggattct aatttcttga
    23161 ttgctcgggc agtcgttgta cgatctactt tgatcatttc tgctagtttt tcttggatga
    23221 ttccaggatt ttcgcaaata cgtactaaat aaagatactg tcctcttgtt aaatcgactt
    23281 ctttgaattc gatattgctg atagaatcta gcgctcgggc aatcattccg atgtctcgaa
    23341 ggatttcagc catttcatcc cacctttatt ttgtttgtaa gactagttta cctctttttg
    23401 ttgcaaatgc aactattttc aataaaaaaa tcaagttctt ttttaataac tagtaaagta
    23461 tattcttttc ttcttttacg aaaaagctca atcacaatag atctggtttt tgttttctaa
    23521 aataagtaac tgtttcttcg ttgttcgctt ttctgatagc tttggcaact cttctatact
    23581 aaaaaatccc atgttggaag tttcattatt ctcaataaac ttggcctctt caccgtggat
    23641 cgcacaagca aaaacaagtt tataatactg aaaaagctgt ggaatatctt tttgtttatt
    23701 cgtatcaaaa actgctcgca actgagtagt ttctactgtt aatcctgttt cttcatagac
    23761 ttctttacgc acattttctt caggagacaa tcctatttca gcaaatccac caggaagtga
    23821 ccattctttc gtccgtttat cttcgattag taggaccttg ccatcttttt tgatataggc
    23881 acgaacatct acttttggtg ttggatgtcc ttctccaatc gttgtgagcg cttttatttc
    23941 ttcgaaagtt tcttttccta tttcactgat cagttccaat gaaatcgtcc ggatctcctc
    24001 aaaacgctct ttatcaaata catcttttcc ataatataga ccagcttgag aaagtgcgag
    24061 tagtcttttg tattgagcca acttcttgtt cattctcttc ccttcttttt tagcaaatgt
    24121 atgactatgt aatcaagtat agaagactag tttaattacg gcaaataaat ataatgaaat
    24181 ctgcaataaa taaaagaatg ttaaaaaact cgagaacaaa agacattcga cttctctggg
    24241 gctgtgaata aatggcgttc aaaagcttgc atctgcggta ataagcccca ccaaacgaaa
    24301 aatatgacga gctattcttg tctggctgtt cttattaatt gaggcaggac agctttttca
    24361 caacctcccc actaaacggt gttcaatcag ctgatgctcg gtattcacta aaaaaacggc
    24421 aaaatatgag gagctatttt gccgtttttt tctataatac tcatattaaa acactgactt
    24481 cacaacctct tccttaaacg gtgttctcct accaactcct cagtcacaag tcacaatatt
    24541 catcaaacat gagaagctgt ttcttgaaat tgctccttgt gactcggtgc tgaacggtag
    24601 gctcacgacc tctcggtaaa cggcgttcaa aagccaattt ttcgatatta agccatttct
    24661 ttgttactta ttgtcattga ttttttttct aatttatcca atagtggagt gtaatccact
    24721 tgagtatagt ctgttacatc aaattcatat agtgttccta actggaattt gtcatatttt
    24781 cggtcggcga tgatcttttt gaatgcttct ttcgtaatat gattggtccc tttcgttcga
    24841 tcttccaata cgtcaccata gtgataatga tccatgatat agctcaaatg acgatctgat
    24901 tcacgatcac gtttgtaccg acgttgccat aacacttcaa agtctgctgt taggcgaatc
    24961 gtgatcacct gatatccgta tctatctgct aattcttgga gtcgtgcttt ttgcttatca
    25021 ctaaaaggat actcggacac aatcactttc tttcctgctt ccatatacaa atcaagtgct
    25081 ttgtaataga aaggataaac tttcgtcctt tcttgttccg cccgttcttc caaattgtta
    25141 aacccgatgg attctgcata gtattccttg atttcatcga gcgtgatggc atacatatct
    25201 ggaaatcgtt cccgtagttt attcataaga tatgtttttc ctgtaccagg actaccagcc
    25261 agaagaatga aatacttttt catctcattt atttcctaag ttaattggac tttccaagtt
    25321 cataaacagt ccaatcttat gcttgacaat ttcttttact gcttcatttg ctggaatcac
    25381 attatggcga agagacttgt tgatttctgt ttcactaaag gtttctttag ctactttcgt
    25441 ccagttgact aaaagctccg ttccaacatt gaatttgcgg atcccgttat tgatcaattc
    25501 aggataatct tcttctttca cacctgttcc tccatggata actaggggga catcaactac
    25561 tgcatcgatt tctttcagca agggaatgtt tacttctgtt tttgatttga attgtccatg
    25621 attcgtaccg atagcaatag ctaatgcatc cacgcctgta gcttctacaa atttcactgc
    25681 gtcttccggt cttgtatata ccttgtcatt ttcagcgaca tggattcctt cttctgtacc
    25741 gccgattgtt ccaagttctc cttctacgga aacaccgtgc gcatgggcat attctactac
    25801 tgcttttgtc ttcaggatat tttctttgaa aggcagatgg gacccatcat acatgacaga
    25861 agtatatccg ctgtcgattg cttctttgat atcatcaaag tctcgggcgt ggtctaagtg
    25921 caagactgca tcaaccattt cttcttctgc aatagctgtc attacattga ctaacacatg
    25981 catgctgata tatttagcag tatcgacact tgtttgaata atgattggcg aacccatttc
    26041 ttttgctgcg cctagcatgg caggaagcat ttctaggtta tgcgtattaa aagctccaac
    26101 tgtaaaattc aactcttctg ctgtttttgt tacttctttc aatgttgtat acatctttta
    26161 ttgccacctt atctttttat ttgtttcctt tgatcgttac ttgttttgca atttgtcgca
    26221 tctcatccat tttgcccatg tagtaatcga tcccttgatc atcaccagca cgagcagcat
    26281 ctgaacgctt ctggttatag aggctcatca gttttttata cccatctccg atcgtctgtt
    26341 tattttccaa gctcttttct aaatattgga tggcttgatc gttctcatac aattcagaaa
    26401 atttaagtcc aacttgttca taaagttccg ctaatttatg cctatcttgg gtagtggaaa
    26461 tctcttgttt caattgtgta atctctgatt gaatcttttc ggtcgcttct ggcgataggg
    26521 ctttttcttc ttttgccaga acttttttcg gttctttttc ttttttctta aaaaatccaa
    26581 acatcatttt ccctactttc aattaaaatg ctttcaaaac tgggcttaag atccaggcat
    26641 ataagagtgc tgcggctact gtatctacat cggttgctgt agcattgatg aatcccatcg
    26701 aattaaagat cgttactagc aaagcgggca ataatgtaat aaagaaacca tgagcaatac
    26761 cgccaatgat cgctcctcgg cgtccgccaa ctgcgttgcc aaatatccct gctgtccctc
    26821 cggcaaagaa attggttagc ataccagata aaatcatcgc taagccgaac atgggcaaag
    26881 taaacatggc aataatcgta ccaatcgttg tcgtaatgaa acctaaaatg acagcatttg
    26941 ggctataagg aaagaaaact ggacaatcta aggcagggat cgcatcagga actaatttca
    27001 tagctatccc tcgaaatgcc ggcacgattt cacctaacag tagacgtaca ccagctagca
    27061 atacatacac acccactacg aattggatgg cttgtaaaaa ggcaaacatg atatagtttt
    27121 gatctcctga taattcagaa gcgaatggtt cgcctgcaaa taaaacagtg atgatatata
    27181 gcgggaccat cacgaccatg acagacaaat aagtatcttg cagaaattcg aaatgtgtcg
    27241 gcaacttgat atcttcgatc gactttttat tttcgccttt ctcaccaaaa agcttagcga
    27301 caccggcttc aaataagtac ccgatcgtac aaaaatgacc taaagcaata tcatttgatc
    27361 cagtgatttt acgaatgatc ggttgcgcta ctgccggcat agcaatggcg aaacaagctc
    27421 cgataaaacc accgaccaag atcaatacga tccctcgcag accggcaaaa tagccaaaga
    27481 ctgtcgtcat cgttgccatc cataaaattg cttgaccatt gatagattca atagaaggga
    27541 tgatcccttg catatgaaat ccttcagtaa agattttccc gaaataagtt aaacttccaa
    27601 cgatgatgct cgaaccggca ctcaacactt gaaatcctag gagtgtcttt aacgtgccag
    27661 agatgacttg tcctgctgat ttcttctgca gtagtagacc caacatagca atcaatgcaa
    27721 tggtgatcga tgcctgagtc aaaatatttt cgatgataaa attgataacg ctcatgtttt
    27781 taccctcttt tctttttgta tttagataac tcccttatct tgcagaactg gggtgatttt
    27841 ttcttcaatt tcattttttg aaacaatatt tttcaaatag atcatcgccg ttttaggatc
    27901 aactgcgaac ttttcgaact gcgaacgaaa attttctgct gtgatgatca catctggttt
    27961 catggaaact gcggaagaaa tatcacaatg gtccagtttg gcttctactc ctaatttgtt
    28021 caaaacatcc tcagcagaca tctgtgctgc aaaactactt cctaaacctg cgccgcatac
    28081 gaataaaatg ttcaatttgt tcatctttgt tctcccccgt atcatttatt atttctcaac
    28141 tactgaaaaa agcagttgtt tgaaatcttc gatatttgtg cattcaatca atcgatccaa
    28201 cttctcttcg ttgttgatca attcaattag ttctttcatg atgttcagat gcgagtagga
    28261 gtctactgct gccaaacaaa aaataatctt tactggatcc atttcaggat taccgaaatc
    28321 gattggttgc tcaatcgtag ctacgctgac tcctaattta ttgaccccat cttctggtcg
    28381 ggcatgggct agtgccatgt gtttgccaat cacgatatac ggtccgtaat cattcactgc
    28441 acgaatcatc gcttcgacat agcgctcttc gacaatgttt tctttaacca atggtctagc
    28501 agctagttca atcgattcct cccaagtagt ggctttttct ttgatcatga tattgctgtc
    28561 cgtcaaaata tcttttaaca taggctggat ctcccttttg ttgatttcta aattgtttgt
    28621 ttcgaataat ttttctaact tgccatagat gattcgatct actcggccac cactttcttt
    28681 catgacatct attatttgag tgaataactc cgtcgattca tgactgttag gctctaaccg
    28741 ctgtagttct tcatttcttt tcaaaaagtc ttctataacc aagatattcg tctcagttaa
    28801 aatcggatcg acaactaaaa gcggcttatt tcgataattc aattgaaagg tgctgaaaac
    28861 cagattgaca tccaatttat ctactaattc gatttctttt gaacttaaaa ctgcagtaat
    28921 ctcgatctga ggaaactttt ctttcagatt ctctgctaac agatttccag tagccatccc
    28981 atggttacag acaacgactg atttataaac ataattcaag tctcgcttga ttacactggc
    29041 gatcgtcaaa aagtggatga caagaaaagc tatctcgtcc tccagtatct tgccaccaat
    29101 tacttcttcg atcgtaggaa caaaatgagt gactgcgcgg tagattggga aataatttgt
    29161 tcggatgttt tctttcaatg gattcatgac ttggatatga ttcttacaat cagtgcagcc
    29221 atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg tacgtgtgtc
    29281 tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac ccactcgatt
    29341 gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata atttctttct
    29401 acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa tgcagaaaag
    29461 ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc atgtttcctg
    29521 attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat atcatcttct
    29581 tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac caaaggaaaa
    29641 taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat aaagaagtcg
    29701 gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga tcgttctgaa
    29761 cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata actgaccagt
    29821 gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg aaattcttct
    29881 tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac tagatcaaaa
    29941 atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt ttctaatcga
    30001 gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt acggatctcc
    30061 ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg gatcgtccgc
    30121 tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg ggctgtcatg
    30181 attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt ctgatttcaa
    30241 gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa gtggaaagaa
    30301 agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa cgaaaaagac
    30361 atacgcctat tattacaaaa attttgccca tccatacaaa aaagaggttg tgaaaaagct
    30421 gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt ttttgtttgg
    30481 ttgttcttat tatcgcagat gcaagctttt gaacaccatt tagtggagaa gttgtgacag
    30541 agatgttcag ccttgagcga taagaagcga ttttgaaaaa tagcttccca tattttacaa
    30601 aatcgtgcct tattgccgat aggctatctc tggcacaccg tttattcaga aaaaggagtt
    30661 gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc agcataatcg
    30721 gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa taccatatct
    30781 gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct tttcgatcga
    30841 ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg tggatctgtc
    30901 gataatttcc tacttcctga atagttattt ttttaggtat gatttcttac accgtctgct
    30961 ttgttttttt gcagaacttt ctgattttcg gcaaacagct tgtctgtata acagcttctg
    31021 gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat cttttggatt
    31081 tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa tatctccgct
    31141 ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac ccctcctact
    31201 gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc tgtacttgga
    31261 ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact gcccccatat
    31321 gaacgaccgc caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc tccaccatga
    31381 ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc cactaacaaa
    31441 atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta ttacaaaaaa
    31501 ctatttttat catagccttg ctaaaaggaa gagtcaataa ccagatgcat aaactgtttt
    31561 tttagcaatt ttgtcttatt tagtcattga gtaacatcga acagatgtat gtgtcggcag
    31621 tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct gcgcttcctc
    31681 caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgaa cgatttggta
    31741 aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt ttctaatcac
    31801 tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac atatgcattt
    31861 gtttctgtac atatgaatca ttatctagct ccttagctgc ttggattgca agcctgatat
    31921 gcggataccc taatattgct tcttcatatg caccatttac gccatatttt tgcttcaccc
    31981 tatgaccatg agtgtttttt ttatgacgat attttgtatc aggaaaagca gcaagcttgc
    32041 tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt ttttgtgcaa
    32101 tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg atgccatttg
    32161 tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt tctcttaact
    32221 cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa ggagttagcg
    32281 tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc gcatccagtg
    32341 catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct tcctctacca
    32401 acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg acactcactc
    32461 cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg atatgaagta
    32521 accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga atcatgactc
    32581 ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg aaaacaaata
    32641 cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat ggcaattttg
    32701 gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg atgactaaac
    32761 tgtataaact ttggatcgta ttcaagtaag gcgcattcgc aaagctcaag tctcctggat
    32821 gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt aagaaaagat
    32881 aacgtactct gtccaaatat tgataaactt tttcatgata aacaaatgcg gctaccccat
    32941 aaatcccgta aatcatgaaa ctagcaacaa accgatctaa caagtaccag ctgtcatgat
    33001 aaggcccagt caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg
    33061 aaccaatcaa tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa
    33121 caaaaaacgg catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg
    33181 ctccatcacc tgtgacatat ttcagtaaaa agcttgcagt atcgtatacg gagtttgttg
    33241 ttggactgct ggaaatagcc aaagataagc cgtcgtccat agaagatacg gaacgactag
    33301 ttcaaaaaac ttttctttca aaaattccca ataagacaaa tgctggcttg tttttaccat
    33361 attataaaca attgcaaaaa taaacattgg tgctgtgtat ttaacgatga cgtaaaaggt
    33421 accaataaaa gctgtatttg ttgcgctgtg gctgtttgcc aaagcaaagc tcaatatcgt
    33481 ttgcatcata acagccttta cagctgatac tttctggaag tcacttacgt tgattttgat
    33541 ttttttgttt tcaaacatct ctttctctct ctttttcttt attaccaaag ttctttagtt
    33601 aatttaggtc cttcgactgt tttcaataga atttttttct ctggctctct caaatactct
    33661 tttagtgaaa aaccgccttg ccgagtcact acttgggtat cgaattgctc aaaaaaagca
    33721 ggatgcgatt gaattacctg aattggcaat tcaatcggtg aatttgcgta cagtagcaaa
    33781 tcaaaatcac tggtttcttt tactgccgga atcccagtcg ataattcaaa tcctaagctg
    33841 ccgccgattc cccatttaca tcctgataat atgtttctag cagcatgaaa ttgctgataa
    33901 acaggataat ccatgatttt ctcttgtcta tacgattctt gttcgatgat gtcccacgga
    33961 tgaatgactt gtttgacggc atgttttgag atttctgttg cccatctctg attgcgggca
    34021 ggtccacgta aaccaatcgg tagtatttct gcgtgatccg tcgacgcacg acgaactgtt
    34081 ccgaacatct tttcagttag aacgacccat tcaggcaagg tgaacccttc tatttcatgt
    34141 ttatcaaaaa ggacaatatc atgtgcttga atcatttttt atgcatccca ttcttcgtcc
    34201 attttggcac ggactttatt tgtttcgaca cgtccgaatg ttttggctgt ttcgtttgtg
    34261 tatcgatttg tcagcatcgt gtcatttgta ttgcggacat cttgaatggc ttcattgatt
    34321 gcttcgatga ctttgctgac attttgttct gaagcagctt ggtcggtgat atcttctagg
    34381 aaatgataga tcgctcctag ttttgtataa ttattgatat cgtaagcgat agctggaact
    34441 ttttcagcag ctgcttcgat ttcagcaacc gaacgttttg tcacacgtgc agcactttct
    34501 ttagacatcg cttggacggt aatttcttta ttgtttaaag caatcaagcg gcttgattgt
    34561 aatccatgtg ctaaaaatgc acctgaaata gcatttcctg caatcaatcc aataactgga
    34621 tatccagctt gacggaattt tgcataagca gcagcactat tagccaaagc cacatggata
    34681 ccgattaatt cttcgttata gccgtatgct tggcttggta catcgatcac aacgatgatt
    34741 ggccgtttca cttttttatc tttatcttct tcgtaaacgt gatccaaaat ttgtcccatg
    34801 cggaaacctt caactaaacc aacttcaccg tttcgtacac ggtacatcgg gtttttagga
    34861 tcaggtacga ttgatatcac gatggtttct tctatgaatt tacttgattt accataatac
    34921 acagtactaa tagaagaagt tggatttttc atgccagtta gtgccgcaaa ccaatcgtaa
    34981 ccaacacttg ctgcagctgg ttcatttcct tctgctactt ctggtaagtc aattgatttt
    35041 gcttgatggt tagcaattgc ttcattgtaa tcgtcaatgg ccattggttt tgaaagatct
    35101 aaagaatcaa gtaatgataa ataaaatgct gagctttcac tgcgatgcgt gtcttttcgt
    35161 tcgtccattg ctgcgatgac agcagctttg attgcttcta cactatcagt cactaattca
    35221 tcaatgattt ttgactctac ccgttgacga gatcctaatg tattccaaat aaagtctttg
    35281 tcactagaat caaattctcg aacgcctgct tcttgttcaa taacttctgg tccattcaaa
    35341 ccgactctcg ctttttttgt tgcgattaaa taactcatta atgctgaagt aatcgacata
    35401 ccgccaaatg atcctacacg tcctggaatc aaaccgatga ctggtacata ttgttttaga
    35461 gcaatgatta catttccgat ttctgaaata gataacagtc cgtagtttgc ttcttgcaaa
    35521 cgaacaccac ctgtatctag tacaatgact ggaaagatct catttccttt tttattttct
    35581 tctaacacat gttcaagtgc agcaacgatt tttgcaccgg aaacttcacc gataccgcca
    35641 ccttggaatt ttccttccat agcgattact actgcttgtt tgccattgat cgtgccacgg
    35701 ctgacaacga tcccgtcatc actttcaggg acgattcctt gtgctggcaa acttggcgcg
    35761 atgatttgat cgaatggatc aatcaattca cgtccattgt caagtagagc gttcactcgt
    35821 tctctggcgt ttaattctac aaaactattt ttcatctgaa agttcctcca ttgcttgcgt
    35881 caatcgtagg tacacaactc ctggtgtagc accgaagtca ttgatcacga tatctgctga
    35941 aattggataa cgatcaaaaa atctcgttaa tacattgttc catacttcgc cgaagccatc
    36001 gcttcctgta caaattttta cagtagattc tgttttttct gttggaaaca tcaagatttc
    36061 caaatctcct gaaccgacca ctcctacatg gattttctta ttgatcggct gtttcgttgg
    36121 atatttataa gctaattgtt ccatggatct ctcccctttt tgtaaaacag agcatacacg
    36181 ttctgcttat tcgtctttct tcttccatct gggtaaatgg cgacaaaagg tttttctcgc
    36241 caattttatg accaagttct gaatttcatt ggtggttcat acaggccatc tgaccattcg
    36301 atcaaatcat cgattgtttg tgcagctaat aatgaacgtt tcgcttcact gcgtttgata
    36361 cctagatctt ctggtaattt cacgatgccg gcttcacgca agctatctag tgattctttc
    36421 gtgctagtca ttccaagagg tgtaacaccg ccaattgctg caattgctgc ttgacgttct
    36481 tcttttgttt ttgctttgta caaataagca attccttctt ctgtcacgat atgggtagta
    36541 tcttcgctat agatcatcac tggtgcattg gctaagcctg cctgtttttg aacaactaat
    36601 gcatctaatt cttcgacaaa gactggtttt ttatttgaac catatgtttc aaccatttga
    36661 acaactaatt tttgtccttt acctaatgga tcatcattgt cgcgaagtga ttgccatgct
    36721 ggtgtagaat gacgacgacc gccaggatta tgtcccatgt taggcgctcc accaaaacca
    36781 gataaacgtc cttttgttac ggtagaagaa tttccttcgt aatctaattg caaggttgaa
    36841 ccgataaaca tatcgattgc atattgtcca gctgcttgtg ataatgttcg gttactgcgc
    36901 atcgtgccgt ctttaccgac gaaaaagaca tctgggcgag cagcaatata tttttccata
    36961 ccgacttcac caccgaaact atggatactt tcaacccaac ctgattcgat tgctggaatc
    37021 atcgttggat gtgggttcaa tacccagttc ttcgcgattt tcccttttaa ccctagtgat
    37081 tcaccataag ttggcagtaa taattcgata gctgctgtat tgaatccaat accgtgattc
    37141 aaagattgta cgccgtgctc tgcgtagatt cctttgattg ccatcattgc cattaggatt
    37201 tgcaattctg tgatgttttg aggatctcgt gtgaataaag cttctaattg ataaggttca
    37261 tctgctttta cgacaacgtc tacccagtca ccagggatat ctacacgtgg taaagaatcg
    37321 acaacttcat tgacttgaac gatcacgatg ccatctttga aagctgcagc ttcgacgatt
    37381 gttggtgttt cttccgtatt gaaacctgta tacaagttgc cgtctttatc tgctttatct
    37441 gcaactacta agacaacgtt tggtatcaaa tcgatgaata agcgtccata aagttccaaa
    37501 taagtatgga tatcacctaa tttcattgtg ccgtcttcaa tcatttgggc gacacgcaag
    37561 ctttgtgcac ctgcataaga gaaatcgatc ttgcttgcga ttcctttttc aaaaatattc
    37621 aaatgttctg gtcgtgagat actagacatg atcaaatgca gatcattcac tttttctgca
    37681 tctacttttt caagactttc tgaaagaaaa cttgcttgtt tttgattgtc gccttctaat
    37741 acaactttgt cgccgggagc aatcagtttt tccattactt ctacgatttt ttcagtttct
    37801 acatacttgc cattgagcaa gttgctgatt ttttccaatc gctgcgcttt tttttcgcgt
    37861 ttagaagccc agttgcggtt tggtttttcc ataattagtc atctccattt ttgatataga
    37921 aacgtggcgt catcaatacc atgttggtct agattgatcg tacggatccc tttatctaca
    37981 ccaaattttg tatgaatcag ctttgtcaaa gtattgccgg ggggaaattc aatcgtcaga
    38041 tccattccta attcttttgc caagtccatc atttggttcc actgcacagg gaaagctaga
    38101 ttttccaaca aatctttacg aatctcttct gcgtcctgag tggctcttcc atccgtattt
    38161 tttatataca aacatctggc atcagataga tggacagact gcatatacgg cttgaatttc
    38221 ttgaccgtat cattcatcaa gagacagtga gatggcacag ggactttcag cagcttcgct
    38281 gtttgcgctt ggtgccgttt ggcttctgcc aacgtaacgg ataaaccttc gatactccca
    38341 gataacgtat gttgcatcgg acaattttca tttgacagat aaactggatg gtcaggatca
    38401 aatgttttgg ctaccatttc ctctgcttcg cttctcgtca cacctactac tacgcccatt
    38461 gcataaccgc ttggatatgc ttctttcatc aagactgcgc ggtgatagac tagttccgct
    38521 gcattctcaa atgtcaaaga tcgacaagca acagctgcac aaaaagcacc gatcgaatgt
    38581 cctgctgcaa tatcaggctg aataccattt ttttccattt catctaaata aaatactgct
    38641 tttgtcagta atgctagctg gataaaaacc gtatcttgat agttttcttc tttatcgact
    38701 aaccgatacc ccgtcacatt ttctaaacgt tccatgtaca tttcagggat atccgctaac
    38761 atccctaact tctgactgcc ttgtccagga aataagaaac ctgtactcat gagcctcgcc
    38821 tcctcagcac ttactttttc cactgctatc ttagtcaatt tctgctataa taaaaaatgc
    38881 caaaaaaaga aaaaaccata acaaaaaggt atggatggga tggataatta tgaaattgct
    38941 tcatctgcag tattttaaaa aagtattcga aacaaaaaat gttacccaag cagccaaaga
    39001 attatttatt tctcaacctg ccttgagccg tgcgatcaaa catttggaaa acgaattagg
    39061 tgtccctttg ttttaccata gcggcagaaa cattgagacg accgtttatg cagaagaatt
    39121 ttatccatat gcagtcaaga cattatacac attagaagaa ggaatcaatt attgtcttcg
    39181 gtcaatgaga agatcgttac ttccgtcata ttgtatttag aggtagcttc tgtttctatt
    39241 ccgaacttag tccgaatttt tatggaaaag catcctgata tccaattaac gatcatgcaa
    39301 catcatttac cagatgatat taccgatcct gtactgtaca tcacttcgga gatgaagcct
    39361 ggcatgacca atattcctat catgaaagaa cctgtttatg tcgccattcc taagaaacat
    39421 cctcttgcga aaaaagaaca tctgcaatta gaagatatcc agcgcacccc catcttgatg
    39481 ctgtcaaaga gcaacgcctt ccgtcataca ctggatgcag cacttgaagc gaaaagtatc
    39541 gaattgacga tcagttcgac gacagatgat cctgcgacat tacgttctat tgtcaagcaa
    39601 ggattagctg ttagcttttt cccaaaagtt tcttggtctt acgataaaaa tgatcctttc
    39661 gtcttgcggg aaatcaaaga tttgcccttg acacgaacaa tttatttatc ttctagcttc
    39721 acagaagatc atcctttgat caaaatgatt gcaaaaacga tgcgggaatt ttatttagga
    39781 aaataaaaaa aaaagagctg ggacaaaatt cttgtcgcag ctcttttttc gaacaaacgg
    39841 tgttccagaa gtaatttctt agaaaataag ccgaaatttc ccaaaaattt gagaagcaat
    39901 tttcgtaaat tccttcttat ttcttgaagc taaacatttc tgtcacaacc tcttctctat
    39961 tgtcctagac attcattgcg ttgatttaaa acttccatca atcaaatctg ctagttcatc
    40021 tagcttttct attttacgta gatcaataga gatccaatgt tctttattca tgtgataggc
    40081 tggaaaatac ccctcttttc ctcgcaaaat tccgccaagt tcaggatcga ccttcaaatc
    40141 aagaatattg atgatcctat ggtcacttgc atcatcatag attttttctt ctggaacaga
    40201 catcaggacc ccaaaccatt ttttgctttt ttgatgtctg aatacgcaat aatcaggaaa
    40261 ttttttaaaa atatattctg gagacaaatt gtatgtttca ttgatgtgat cgattagttc
    40321 ttttttcgtt agcatctgct tccatctctt tcttattgat tcgctttatt caaagatacc
    40381 acgtaagaat agaaaaatga atacaagtag ctgctaatca aatacttcga tatttttctt
    40441 ttttatcaac tcttaaatgt tcaatccgcc tgtgttggtc ttgctatcat ctactattaa
    40501 aatgttgatt attgtttgcc cacctatttt ttgattttag tggtatcatt tttcaagttc
    40561 atgatgaaat tcttatcatc agtaaatgct ccagaaaaat aaacaatgat tgaaaaatca
    40621 gttgaaactt gaccaccgtt tattttctcc gtattcttag aatagaaggg agtctgattg
    40681 atgtattcac taatgaaaaa aatcattacc gaaaaagata ttcgacgtca tgtttcttta
    40741 gtagaacaat tgctgaatca tacaaagata accgtaaatg aattagctga aatcataggg
    40801 acaaccgaac gaacgattta ttctgacctt caatctattc gctctcaact gcctgaaggc
    40861 tgggacatca ttagcgatca agcagggatt agtttgcaaa accagcaaaa tttattagca
    40921 aatgaccttt gggagatttt tttcaaacaa tcagtcagtg tcgaactatt gaaaagtctg
    40981 ctttttacaa aaaaagttgc tgtccctgat tttctagccg accatgggct ttcttatggg
    41041 acattgaaaa gacatgtgac taaaatcaat cagcgtttag caagttacga cttgcagatc
    41101 gatttgacga aatataccgc ttctattctt gggaaagagc gtgcgattcg cactttctat
    41161 catcgactgc tgattccttt tactcataac aactattttt tcgaagatta ttcgattcat
    41221 gaatcccatt attttcaatt tttaaaaaca ataaatcgaa cggagctagc ggttgaaaca
    41281 gaagagattt ttggaacatg ttggttcttt atcaatacga tccgtataaa agcgaattgc
    41341 cgattagatt cttctatcca tatcaacagt acactctcct ccctgtatga ctctgcattg
    41401 aaaaaattgt atttaacgga aggtatttat ctcaaagaca ctgagctttc ttttgcttct
    41461 ttctgctttc tggaaagttg gaattacaac aataactatg gacaagaaac cgcttgctgc
    41521 ctgcatcatt ctccattttt cgaacgcctc gaaacgtttg tagaggaact agcttcagag
    41581 ctgtctcttg atcaactaaa aaaacatctc taactgataa cttggctctt ctcgtattaa
    41641 aatatcatga atcgccgata ttgattgaag cattggaccg tcaataccat tttttttaga
    41701 aacatatgat cagcaatatg cacatttgtc tcaacagaaa gagaatttac tgaacgatct
    41761 aaaaaaagaa atggaaatca atgaaccgaa tttcttcctt caactcttat ctttactgat
    41821 ccaacaaacg attttttcta tcaaaccgaa tttgttcaat gtctatttta ttttccaagg
    41881 agaaccttca tggaaggcat tctttcagca ggaattaaaa gattacctgg gaaaacgtgt
    41941 ctgcttctta cctatcgaac taaccgatct ttccactatt tctttcgaaa aaacagatat
    42001 cttgatttcc aatttcccgc tggattctct agatatccct atcgtataca tttcttctat
    42061 tcctacgaaa aatgagctca atcgtttgac tgaactcact ttcaaaactt ttttatagta
    42121 acggctagcg actgtattct ctagctgttt tttctttttt gcgaaacagt ttattcatga
    42181 tccctttttc tatttctaca actaagaata gaagaatcac atttgctcca atcaataact
    42241 gttgtgtcat cgttaaactt actgtaccga tcagctgctg gccgactggt agaaaaataa
    42301 ccatcccttg caataaagca aggataccta atgaaagaaa aagcgctttg ttttgcaaaa
    42361 gaccctggtt caatgacggc ttggacaact ctctgcaatt gatcatgtaa acagcttgag
    42421 ctaagacgat attttgtaga agaatggttt gctgtaagct ttgcccttca aactgcatag
    42481 ccaataaata ggcaggaacc atgatcagta gggagacata gatgatccga aacaaatgat
    42541 aaccagatag gattccttgc tttggatctc ttggtgggcg cttcatgatt tctggatctg
    42601 gcgactcgaa ccctagtgca taagataaag tgattgtcgt taccatattg acccataaaa
    42661 tctgtactgg gaacaaaggt agcgggcgat tcagcataag cgcccaaatc aagatcaatc
    42721 cttgagctaa tgcagttggc aagaagaaat tgatggtttt ttgcaaatta tccaaaatcc
    42781 gccggccctc ttttacggct tttgcaatcg tatggaaatt atcatctcct aaaaccatat
    42841 cagctgcctg tttgcttact tcactacctt tgattctcat agcaattcct acatcggatc
    42901 ttttcaaagc aggtgcatca tttacgccgt ctccggtcat tccaacgatt tatccatttt
    42961 tctgcaaagc tttaacaatt cgcagtttat gttctggcgt cgttcgagca aagacatcga
    43021 ctattggcac ttgctgaatc aactcttcat cagacataag atccaaatcg atctcttcta
    43081 aaactttggc agtatgtttt aagccaattt gttccgcaat cgcttttgct gtgtctttgt
    43141 gatcccctgt aatcattttc actgagatcc ctgcttgttg acattccttt acagctttga
    43201 ctgcactttc ttttggcgga tcgatcaatc cggcgatccc tgcaaaagtt aattgggtta
    43261 aagtctcatg cgtgagttcc tgtttcgaat ctactttttt ataagcaaat cctaaaacac
    43321 gctgaccttt tctcgcaaat tctgcagctg tctgactcca tgcttcttgt tctgcagaag
    43381 aaagagttga tttagcaaat aatacttctg atgcaccttt gacgtaaatc accgctcctt
    43441 tttcctccgc atgcatcgtt gccatatatt tgtattcaga actgaacgga atctttgctt
    43501 ctattttttt caaaggcaga ttggctgttt ctgtgtgtcg aatcagcgca acttctgtcg
    43561 gattaccact taaattttct gttttctgtt cttcttttgt ttttaattcc tgacagtttt
    43621 tcataatgga caacacgcag gcttcttctt ttgcagctac atccacaact gtcatttcat
    43681 tttttgtcaa tgttcctgtc ttatctgaac agatcactgt catagaacct aatgtttcta
    43741 ccgaaggaag tcctttgatg atcgcctttt cttttgccat ttcatgtact ccaacggata
    43801 ggatcatggt caaaacagct ggcaatcctt cgggtaccat tgacaccacc aaagcaatca
    43861 tagccgaaag aaggatatgc caatccatac catatcgaaa tgtcgtaaaa ataactaaga
    43921 ataggctcaa acaaagaatg ccttgaaaaa tttgtttgtt taatcggttg attttcttaa
    43981 tcagaggcgt cgtttgttgt tcgacctatt gcaatgcttg attgatttta ccgatttctg
    44041 tcgtgtttcc tgtttctaca acgacaccga ctgcagaacc agattgtaca agcgttcctg
    44101 aaaaagccat atttttctgg tcgccgatcg attcttcttc tgtcaaaacg gcatgacttt
    44161 tttcagatgc ttctgattct cccgtcaaaa tcgattcttc cactaataaa tcatgtgctt
    44221 cgattaatcg gatatctgct ggaacgacat ctccggcacg taagacaatg acatctcctt
    44281 ttaccagttc tttcgcaggg attttttctt gcatcccgtt tgatagtact atcgcttctt
    44341 gtcccatcag ctgcttcaaa ccattcaatg attcttccgc ttttctttct tgccagtaac
    44401 taacgagtcc attgacgatc actacgaata aaataatact tccttcaata tattcactag
    44461 aagcaaattt caaaaaagag gcaatgatca acacgatcat tagcagatca gtaaagtgct
    44521 ttgctatttt tttccatcgt tttgtctgct gccttgcttt tatttcatta tatccttgat
    44581 cagtcaggcg tttctgtcgt tcttcttgcg acaagccttc tgttgatgtt tgatagtttt
    44641 tcaatacatc ttctaccgtc aatctgtacc agttcatcct atcccctcct gtttaattga
    44701 tactgttatt atacgcaggg aagttttttc aggcgtatcg attatttcag gggggtctga
    44761 aataattcgt tttgcagaat gtatctgggc ctaactgata tttctattgc ttattctttt
    44821 atatacaaaa tttaagaata caaaccagat aaccaataaa aaaggaataa agcgtgtcgt
    44881 gctttcgaat aacaagctga aagcaattga agtaaaaaac accaacaaag caagatcttt
    44941 atatctttgt gtagtgttcc gtttcttttc tttaataaat tgaacatgtg tacacaagat
    45001 cgaagaccac acaaatagaa aacaactcgt tgtcatgcct gccaaaagct gaaaaaacaa
    45061 tcgactatca gctacaaaaa aatgtagaca aagaccggca aaaaataaca ttcctgtaat
    45121 taaaataccg tgtaaaggta cgcctttctt agaaagcgca caaaaccaat ggggcaaact
    45181 tttctctttt gctgtttgat ataaaatcct gctagtactg tagactgcac tatttgctga
    45241 ggacaaagaa gcaaccaaaa tcattagatt gacaattgct gctccgcctt ggcaatggat
    45301 catttgcagc atagtcacta aaggactttc ttttaaatct aaacaatgcc atggaacaac
    45361 aaataaaatc gacaaaatcg ttcctatata gaaaaagaga atacgccaag gcagacagtt
    45421 gattgctttt ttcaaattct tttgcggatc acttgtctcg ccaacggtta acccgatcat
    45481 ttcaattcca gcaaaactga ataaaaccat aggaaatgag actaccattc cagcaaagcc
    45541 aaacggtagt aattcatcga tctgtccaaa attttctttg attccgatag actgggtatg
    45601 aaaatctgag acactcaatc ctatacccaa taagataaaa aggaaaatcc ctaggatctt
    45661 gatgattgag aaaaaagatt ccaattcacc aaaccacttg actgcaacaa ggttgactgc
    45721 cattaagatc attagtgcgc tacctccgct tatcaaagct ggtacatgta caaaccagaa
    45781 atggatatac aatcctattg ctgctaattc cgcaagtcca gctccaagcc agcaaagcca
    45841 ataagtccaa ttgacaaaaa atgcccactt tttgcctaaa taatagtcaa cgaaatcact
    45901 gatagagtta aatgtactat ttgctaaaaa taaatcaccc atggcccgca tcaaactata
    45961 aatagccaaa ccgcatatca aataaacgag aataacagct ggccctgctg atgcaattgc
    46021 ctttgctgaa cctaaaaata atcctgttcc aattgcgcca cctaatgcga ttaactggat
    46081 atttcgatta gttagagtcc gtttcattgc cggtttttcc atcaagttca cctttttctt
    46141 tttcaagcag catggcgact tcctgttccc aagaaggttt ctttattttt tcaatacaga
    46201 gtggtactac aaacaaaatg acactgatgg ctgtgactgc aattagattg atccatgttc
    46261 cagctttcat cgtcagtccg acagaaaatc cgattgccgc aaataaaaca ataacgacag
    46321 tccaaactcc aagattgctc tttttctctt tttttccaat tctaaatggt cgattcaact
    46381 ttgcatgtgt ataacgcaat ctcaaaactg cgatccccat gatgacatag acgatacagt
    46441 agataacagt agttgaattt acgagcatca aaaatgcttg attgacgcca ggaatcagca
    46501 aataaaaaag tgcaaagatt gagataatga cagactgagt caaaataacg gatttggata
    46561 cgtcaaattg attcgtcttc caaaaattga attttggtgg atacgcacct tttctagcac
    46621 tttctgtcac tgtctttgct ggtcctgagg cccaagcaga taattggact gctacaccaa
    46681 tgaagacaag taaactaaac agattcacaa taagatgtgg caaaccaaga atttggcaat
    46741 aaatcgaaat agattgcgcg atattattca attccatttg tccttttggt acgacatttg
    46801 ctacaactaa agcattcaaa atattgacga aaaatataaa aattaacgcg gcaaatactc
    46861 cgcgaatata cgttttaact ggatttttca atcgagtgat atacacagag gacatttcga
    46921 taccagtaaa aataaacatg atcggcgcaa aataaacaaa tgaggatgca gtcgtagtat
    46981 ctggtattaa tttgtcccat gaaaaactgc ctaatgttcc ggttggtacg atcccaactt
    47041 tgatccacgc agcaaaccct aataagagca tcatcgtcaa aggcacgtac aatcctaacc
    47101 aaacaccgac ttttccgccg atttttgcca tatcaaattt caaattcaaa aaagtgatga
    47161 tccaataaac gactaaaata acaactaatg taaatttgct gttcaaacca agcggcacat
    47221 tatcgataat attaccaaac aacggagcaa gtgctgaagc gaccatcacc atcccaggaa
    47281 acatttggac ccataacagc catgagacaa cgaaccccca tttttttcct agagcattcg
    47341 atacccaaag ttctggacca ccttttttgg gaaacattcc ggcaaattca ccagagatca
    47401 atgagattgg aaaagcgtac aataatactg caaccagcat gtaaaaaatc atcgtccagc
    47461 tcgttgctgc tacatctgga atatttcgta cacttgctac aagggcgcag gtcattccga
    47521 taaaggtcat ggtcgtgatt tgctttgatg aaccagtatc tttcatcttt attccttctt
    47581 tcaatagcga catatgtttt tgttttcttt tatttttgtt caagaacaga aatgacaagg
    47641 tttcatcgat tcagtacaaa acccagtatc accgaaacat ccattgaacg atcttagtga
    47701 actgggtttg atacatgaaa cgaacgatcc aacttataga acgttttata aaaaagaata
    47761 tcttggcgag gaatatatga aaaacagggg gaaatacaat tgttttgatg aagcaaataa
    47821 ttgtctgttc tccatatgtc tcttgctatt ctttcacaca aaaatcagtt ctattggatg
    47881 atttcgttta gtttcttttc cattgctttg gcgatttctt ttgtataaaa attgaaaatt
    47941 cgatcatcat tcaaataagg agtcatgata gccgcacgta gcagagtgat tttctgttct
    48001 tttttccatt cttctttcgt tagacccatt ctttcaacaa aacgaatcgg agaatcaccg
    48061 taatcttctt gtgtaaatgt agtatgagaa gtaataaacc gttcaccata aacatcgcca
    48121 tccatataag aagaccgatc gaacattttt tcatttaatt cattgatagc gttcaaatct
    48181 gtacagcctt gttctttgaa tacccaattg accatattaa aatcaggatg attcaatgga
    48241 tagacttcga ttgtttttcc tttaacagta aaagtcatat gatcgagaaa ttctctgaat
    48301 ctttgagctg cctcgattga agccccaatc aattgaccgt atccggtcac attcaatggc
    48361 aatacacgat gtgttgtcca gactgcggcg gcggttgctc cagcttttga tccttccaaa
    48421 atataagctc ctaacatatc tggagccttt actgattttt caaacacata tggcgcgaaa
    48481 taagaaatga tatttctcat atttttatgt ttgattacga ttcctccagc agcataaggg
    48541 acatagccca tcttatgagg atctatcgtg acagaatccg cttctgaaat agctctgaac
    48601 ccttcatata cctctttgtc aatcgttacg cagtggtgga aaacatgatg ttcttcaaag
    48661 aattcagcta aggaagcata cggcacaaat tctcctgctt cgtttagaaa cagtgaacgc
    48721 gcatagccgc catatgcggc atcaacatgt aaatagaaat agataccttc atcttttaac
    48781 ctttctctta attggacgat tttatctaca ctgtctactt gaccttcttc tgtcgttcct
    48841 acgacagcaa ccacacctag aattgggatt ttttgttcag ctaattcacg aattgttttt
    48901 tccaaagcat taatatccat tcgataatcc tcttgaactg ggatagcaac catctgatct
    48961 aagccgactc cgcaaatatc taacgccttc atccaagaat agtgttttgt ttgagggacc
    49021 agccatttcc ctaatctttg gatatttttt ccgctacggg aagaagctgc tttgacctca
    49081 tccatttctt cgtccgtaaa gctttcggtc atttccaaaa tttcttcaac agataaattc
    49141 aaaagttccc actcagacat ttttttcact ttttcaggca gcacttcctt gacagctaaa
    49201 ggaatcgatt tgatgcagcg ggcgtaccat aatccttcaa gattagcaat agaaccatct
    49261 gctgcaatgt gtccccatcc gtctgtcata ttgaataatg aagcaaaatc ctgtcctact
    49321 tctgcttcca tttgcgaagt tgccatagaa gattccaatg caacattatt tgggttccac
    49381 agcatcgcat agttgtaagc taataaagca ggcatcaatg tttcagcatt catttgtccc
    49441 cagtaacggc ctgctgaatg ccatgggatc gatcctgcgc gtaatcgctg actgacttca
    49501 tccaagacct ctatcatatg gtcgcgggtg gctagataat ctggagtgag cttatctcct
    49561 tcgctaattg caggcatatc tgaaggaata taattttctc tccatccaag atgttcatct
    49621 accatcttgt tcaacaacat tttataaact ggtccatttt cagctttgtc gcctataaag
    49681 acggccttga tatccatatc tttcattttt cttccctcca tattttgttg gtcaatgtct
    49741 cgcagataca tgtgtttatc tgtaacacct cttcactata gcgccaaaaa tgagaaattt
    49801 tttttataac atcaaatcca cgtagatttt tacaaacaaa aataaataaa gtcggatttt
    49861 tctgataatt aaacgcaaaa aaacgaacat tttttcaata aatcagtgtt ctaaaataga
    49921 taacctaaaa aaagcgaaca aacaaataaa atgactgtcc ttcattcact aaacatattt
    49981 ttattttttt atattgttaa aaattcacaa tttatttttt aatagaatta tctgttttcc
    50041 aaattttata acataaaaaa ccttttttaa cggcatttat atgctttttc agaaattaac
    50101 tgatgatttc aaaaagaaaa catgtcataa tatttcccat attgtgcaaa aaaatacaag
    50161 gcggaggctc tactatgatt gaagaatata ttgagaaaaa tattttaaga cagctgtttt
    50221 tatgtgggca attctatgta aataaagaag tcaatctaga aaagctctcc aatctcctgc
    50281 atgtttgcaa aaccactttg ctcaatgata tcaataacat aaaaaaagaa tttgaagaac
    50341 agatcgctta tacacatcgg gaaaaggacc gttacacttt atatttttca gaacatatac
    50401 ctcgatgcaa gatcatgcag caagtgtctc aaaattcgtt gtttttaaaa acttgtctgc
    50461 tttatttgga agaagatgaa cctgattatc ttcaattaac tgaatgtgaa ttcatctctg
    50521 tcagcaaagc ttattcatta aaaaaacaag tattagctta ttttaatgac tgcgggatcg
    50581 aaatcgaccg ctactcccct cgactcactg aaatggaaag acgtctgctg cttcttaatg
    50641 tgtcgtatcg tttaggcggt tttaattctt gggagctacc tgaatcgttt tttgaacgta
    50701 ccgatcgttt cattgaatcc gtaacggaaa atagtggcag attttatgat aaagaaaata
    50761 aagaaatctt atcgattggt tttgctatca gtttcctacg ccagcaagtg tgtgctgtga
    50821 caatagattc aaaatttatc gaagaaatca aaaaacgtcc tatttacaat tatgtcgaat
    50881 cagcatggga aaacactgat ttccaaacct attataaaaa agaagaattc gcctttattt
    50941 tgacactatt caatctttgt aattatggtt tccattctta tcagttgatt gcggaagact
    51001 ttcaacagct acaccaagtg tttattgaca atactcccga aataaaagaa ctagttgcta
    51061 cctttgaatc tcacttcaat caagaattat tcggaaacca accgttcgaa cgtgcgctga
    51121 ttcatctgat gcgttcggct tgggataact atcaattatt catgccagaa aaattttatc
    51181 ttttaaatga ggaacagaca aatttatata aagaagtcca gacaattttt tccagctggt
    51241 ccagccagtt accttatgat ctacggttga atcctaattg catgcgggct tttgtgatcg
    51301 aattgagcgg aattctccgt ctgacaaaag aacatctgac tatctatatc gtcacaaatt
    51361 cggatgttca ttatctgatt tatcgggaag ccttggaagc tgtaactact ttcgattttc
    51421 aagttgcacc aacaatttat tcaagtatat ctgatataaa gaagtatgcg cagcagtcct
    51481 caaaccgggt attatgtgaa cgtacattat atacaccaga tgcggtccaa tatgaaaata
    51541 ttattcctat ttcgatcaat acgatcgatc gagctatcat ttcagctgtg caaaacaaat
    51601 aaggggctgt gacaaaaatc atgtcacagc ctcttatttg ttgaagatgc ccatttctgt
    51661 aacaatctct tgatacacgt caggctcaca acctcactta ttttggacat ctacgggtcc
    51721 gatctcttta tttaaaaaat aagaaatgat ggttcggata actaccaacg ccgctagttg
    51781 gaaaatatcc tgcaaggtag gtttgataat cgattcgatg atcccagctg aaacaagaat
    51841 ttccaaactt agaagtatat agcctcccaa catcttttta atagcattgt tctcgctgac
    51901 tcggtcgttt tgcacttttg tatggacaaa taaatatttc aaaaaatcct tgattgatag
    51961 acaaacaccc caaaccaata aacagatagc aaagatatca agtcccagta caagtttttc
    52021 aaaatatgga agaagaaact gcatcaactc tgtcgtcatc ctacctctcc tcttctttgt
    52081 ttttctttgt cttctatttc ctgattcaag aaataagaaa tgactgttcg aatgataata
    52141 ataagtgcaa gcttcaaaat atctgtccaa gtcggcttga taactgactc gatgatatca
    52201 gcaacgacta gtacttccaa gcttaacaaa atataacttg ctagcagttt tcttgtatct
    52261 gcattacgag tattacgttc tgcatagttt ttcttgacat gagaccaatc aaaaagtttg
    52321 aatagaacaa gaacgatccc gacaattaag ataccgatag aacaaatatt taaaatagca
    52381 atgatccatt ctagaaattc aattaaattt gagcgaaaca tatacgctac ctactttctt
    52441 ttaatttgtt cctattcttt tattgtaaaa gaaagttacc ttgttcgtct atttaaaagt
    52501 tgttctaatg ataacggttc gcttaaattt ttctttttca ctctcccatt tttctcccct
    52561 catccataaa tcgtggaagt atccaaaaca acgtagcaag ttaaaataag gcttagtccg
    52621 tcatcagctt ttcaaagaag cactgtctcg gtgctttttt gtacccaaac ttctaaaaat
    52681 agaaccatac acctcctcaa atcttttctt cttacctacc ctatttttat ttacaggaaa
    52741 atcagacact tcttcttttt tgtcaaaatt tcctttttct tctcgtccta tcatttggca
    52801 ttctaataaa aacgaactat ccttggatat agaaagagaa aacaaggagg cgtttttcat
    52861 gagtaaaaaa ttaatcaaag tcggcatcgg tttaggtttg cttgcccttg gcgctgcata
    52921 tctaggaaaa aagacaggac tattcgaaga tgacagtcat ttatatgatg aattcgaatc
    52981 aatctagcat cctatttcgt tgaatcacta cggacatact tgaaagacat tggaggaatc
    53041 acaatgagaa aaagtaaatc aataatgatt ggtgccggta ttgccaatat ggcagcggct
    53101 gtttatttga ttcaagaagg caaatggaaa ggggatcaga tcacctttta ttcattggat
    53161 gatcacggtt caaatgatgg tgcaccgacc gacactgtag tggatgaata ttggaataaa
    53221 aaccatccat tagaaaacca aaaaggctat attgctcgag gcggtcgcat gcttaattac
    53281 cgtacctatg tagatttgat ggatctgtta agtcgaatac cttctgttac tgagccaggg
    53341 atgactgctg aagaagatac gagagatttt gatgcaaaac accgaacctt tgacaaagca
    53401 cgtttgatgg aaggtggcaa aggaatcatt gatggcggaa aactgggatt caataataaa
    53461 gaccgtattc ttctgactaa actgattgct atgcctgatt cagaagaaga aaaactagac
    53521 aatatcacta tcgaagaata tttcaaagat gatccacact tttttgaaac aaacttctgg
    53581 tttatgtggg aaacaacatt tgctttcaga acacgtagtt ctgctcaaga attgcgtcgc
    53641 tatatgcatc aaatgattta tgaattcact caaatcgaac atctagtggg cgtcaatcga
    53701 acacgttaca atcaatacga aagtattatg cttcctttga tcgagtactt gaaagaacaa
    53761 ggatgcaaaa tcattttgaa ccgccgtgtc actgactggg aattcaaaga aacaccgatg
    53821 caagatgaaa tcactgtgac tggtttgaaa atgaccaata cactgactca agaagaagaa
    53881 cacgttgtgg tcgatgaaga tacagcagtt attttcacta atgggtccat tacagattca
    53941 gctactttag gagattacga aacaccagct gtagaaaata tggattatgg tgcagcttct
    54001 agtctctgga aaaaagccag tgaacgtttc tacaacttgg gaaatcctga caaattcttt
    54061 gctgatcgag atgcaagcga atgggtcagc tttaccctga cgacgaaaaa ccatttgttg
    54121 ttgaatgaaa tcacccgtat cacgactcaa gaaccaggaa atgccttgaa ttcatttatt
    54181 tcaaccacac cgatcacgcc gttaggccaa aaagatgtca atatgtctat cgtcgtgcat
    54241 catcaaccgc attttacgtc tcagaaatca aatgaaacag ttatttgggg ttatttcctt
    54301 tatccaagac gacgtggcga atttgtggat aaacagtata ttaaaatgaa tggaaaagaa
    54361 atgctagaag aactgatcgg acaactttca aaagtagatc ctggaccagt gaatattcgt
    54421 gaaaaagaaa cagaaatttt cgacagcgtg ataaataata tccctgtcta tatgccttat
    54481 gcttccgcgt tgttcaataa tcgtgccaaa agcgatcggc caaaagtcat tcctaaacat
    54541 tcgaccaatc tggcctttac aggagaattt gtcgagcagc cttatcagat gatctttact
    54601 gaacaaagtg ctgtacgttc tggagaaatc gctgctttcc attttgcggg tatccctatg
    54661 tcccgtcttg tcaaaacacc gcgttacgac aaagatattc ctactctagc tcgtgccgca
    54721 aaaaaaatgt ttgaataacc aagaggttgt gaaaaagctg acctgcatca agtaataaga
    54781 acaaccaggc taaaacagct tcttatgttt ttgatttggt tggacttatt accgcagatg
    54841 caagcttttg aacaccgttt accaagaggt tgtgaaaaag ctgacctgca tcaagtaata
    54901 agaacaccca agctaaaaca gcttcttatg tttttgactt ggttggactt attaccgcag
    54961 atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aagctgacct gcatcaagta
    55021 ataagaacac ccaagctaaa acagcttctt atgtttttga cttggttaga cttattaccg
    55081 cagatgcaag cttttgaaca ccgtttacca agaagttatg aaaaaggcgt ttagtttcga
    55141 gtatgaagaa aaattttgtg aaaatggttc ctcacgtttt tgcataaatt tgacttaata
    55201 ccgagaaact gatcccttct gtcataacct ctttttattt atgtctgttt ctttttgaaa
    55261 acaaccattt tttcaacgtt tactctcttg ccaatccaac atcatctaac ggatacaact
    55321 atttcaatga ttaccattac actaaaaaat cggaaacaca cctctccgaa cacaaataca
    55381 taagactata gaatgtttca tttaagaaaa aaagcgtttc attatcaaaa aggtaagatc
    55441 tcctttaaaa tgaaattatc tgtagtacta ataatgcaga caattttatg aatttgaaag
    55501 gagcatctcc aatgaaagca gtcacttggc aaggaaaaca gaaaatggaa atcagaaacg
    55561 tagatgatcc aaaaatatta gaaccaacag atgcaatcat ccgtatcaca gcaacagcca
    55621 tttgcggctc cgatctgcat ctttaccatc atggtgaagc agttttggaa aaagggtatg
    55681 ttgtaggaca cgaaccaatg ggaatcgttg aagaagtggg atctcaagtt caaacattga
    55741 aaaaagggca acgtgtggtt atccctttta atattagttg tggtcattgt catttctgcc
    55801 tgaatcacat ggaaagccaa tgcgatgaat caaatccaga tcagttatat ggcgggcttt
    55861 tcggatttgg caagttgaac ggtaatcatt ggggtggtca agcggaatat ctaagagttc
    55921 cttatgcaga ctctacttca tttgttgtac cagataatgt tcttcctgat gaaaaagttt
    55981 tatttctatc agatattttg cccacagctt attggagcgt tgaaaacgca ggagtaaaaa
    56041 aaggcgatac agttgtgatt ctaggttctg gtccagtcgg tctattcgct caaaaattcg
    56101 ctgttatggc tggagcagag cgcgtgatcg cagtagatcc agtacagcac cgtctagata
    56161 aagcggctaa ttacaatggg gttgaaactt atttcttaga agacacggca caagctggaa
    56221 cagaattgta tgaactggct aaaggtggcg cagatgtcat tatcgattgt gtaggaatgg
    56281 acggattaga gcctgtcaaa gaaaaagcga aaaatttagt aagcttacaa agcggcacaa
    56341 tctctccatt acagatggca tcgcaagctg tcaaaaaatt tggaacagtc caagtaactg
    56401 gtgtttatat gactccagct tcttcttacc cgctgcaaga attttttatg cgggatatcg
    56461 ctgtcaagca tggacaggca ccaattatcc atctaatgcc aaaaatttac gaaatgatcg
    56521 cagaaggact attcgatccc acacaaatca ttactcattc gctgccacta tcagaagcag
    56581 cacaagcata tgaaatcttt gacaaaaaag aagataaaaa tataaaagtt gttttgaaac
    56641 cttgaattca gtaaaaaata caggtgattt tctttatgcc caaaatcaaa cgaaataccc
    56701 atgagatcga aataggaaaa gaagaagata tcgaaatacg aggacgtcgc ttccgcttct
    56761 atttccaaaa tcgttacaca ttgatctcac tggctgtcga tttattaacc gggattttct
    56821 atatttttgg aagccttgct tccttaacta aaatccccga tcgatatggc acctattttt
    56881 atttggctgg tgctattttc ttgacaattc gtcctattct cagaatcgta aggaacattt
    56941 ttatttacga cgaaaaaaaa caatgaagag aacaagcaaa aaaaagaggc atgagatttg
    57001 aaaaaatctc atgcctcttt tttaacccta tcgtatcact ttgatacaga cgagcggtcg
    57061 tcccactttc ttccttgacc attgtcaaaa atgtccactc gtatcgttca taaaacgtgg
    57121 tatgatctgt aattaaataa agtttttcat acccaagttg atgcattttt tctaatttcc
    57181 gctaatatcc gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa
    57241 agatttggtg tcagatcggg acggttatgg aagtcgtttt caatgacgcc cgctcctccg
    57301 acgatggttt ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg
    57361 attccagtac gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac
    57421 cacttcgcac tttgttttac taattctggg tgttctctta atttgatcca gttatatgta
    57481 accaatgttt aaacctctga ctaaaataaa acgtttacaa aaattataca agtctttatg
    57541 aaaattagca atgacaacaa tagtgatgta aaaaaaaacg gaaaacaatc acttgttctc
    57601 cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat cgtagctacc
    57661 ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc tagtacacca
    57721 cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac ccatggaggc
    57781 ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac actaactaag
    57841 accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat aggtaaccca
    57901 aacatcgttg gttcattaat attgaagaca cctggcgcaa tcgacaagtt tgttacaacc
    57961 atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc taaagttgca
    58021 cctgttcctc ctaagttgac aaagctgtca aagaaaggtt tgttcacgat aaacggtgcg
    58081 ctatgtccag ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt gattgtttgc
    58141 atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga accataagaa tggtgtgata
    58201 aatgcaagca gtaaggcaga tggataagag tttgcaagtc ccataaatgg ttcttggacc
    58261 actgtataga aagaacctac gatatcatca acaccgaatg cagcaaaaat tgcagcaact
    58321 aaagcaaacg cagagatagt gatcattgct ggtagtaatg aagcaaatgc ttttgcaact
    58381 gccggtggca caccatcagg cattttgatg atcaattttt catttccgct taaacgtaca
    58441 aagatttctg ttgaaataat cccaacaata atagcaataa acaaaccgtt tgagctcata
    58501 cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc ggaaacaccg
    58561 tcttttcggt agccgttagc taaatgataa gcaagcaaga aagcaatcaa gacagaaaga
    58621 atggcaaatg taccgttcca agcagcagcc ccgaatcctt tccatgattc accaccaaaa
    58681 attgagttca tcaattcttg gaacccggga atcggtaagt tattgatcat tactgctaat
    58741 gctcctaaga tcattaacgg catactcacc ataaatgagt cccgaatcgc aactaaatgc
    58801 cgttgtgcac caatttttga tgctacaggt ataaaatgtt tctccataaa tgcaacaaat
    58861 ttatccataa atcttccctc ttttctttac tgtagattac gcgttcaatc gacgatacag
    58921 atcaatgatc tcttttgcta aatctgtaaa agctatggat gtcatcagat gatcttgact
    58981 gtggactgtc aaaagcgtga cttcaacgtg atttccttgt gcttcttgtg tcagcatctc
    59041 tgtttgagag tgatgtgctt ggactaaaga ttcctctgca tctttgattt tttcatctgc
    59101 taaagtgaaa tcaccttttt tcgcagcagc aatcgcttcc attgcatcgc tttttgcatt
    59161 tccgccaaac atgatcagac ccatgatggc ttctagattt ttttgatctt ccatttattg
    59221 tatcctccga taatttttat tatttgttta ttagtttttc tgcttggtcg agtacttttt
    59281 caccattcat catgccatag tcagccatat tgattatatc taaaggaatg cctttaggtg
    59341 ctagcttttc agcaaattga ttttgcataa agcgtacttg cggtcctaaa agtaaaacgt
    59401 ctacattttt agattctagt tgattatccg catctgaagc agatacagca aagatgtctg
    59461 cttccattcc ttttgcttct gctgcctttt gcatttttgt gactaggaga cttgtactca
    59521 ttccagctga acatacaagc atgattgttt tcttttccat tttaaacacg ttcctttcta
    59581 tacttacact tgtatataag caagtagcgt gccaacttta aaagcgcttt aaaaagttga
    59641 tatcatcaca tttaaggtct ataccaagtt gcatacacac taaaaaagaa agtgcacact
    59701 aaacacacaa attaattttt attacctttt ttcttttaac gtgcacaaaa aaagttgtga
    59761 cacaaaactt gtcacaactt tttttcgaat aaacggtatt caaaagcttg catctgcggt
    59821 aataagtcca accaagttaa aaacataaga tgttgttttt actttgctat tcttattact
    59881 tgatgcagga cagctttttc acaacctctc aataaacggt gttcaatcag ctgaccctgg
    59941 attttagctc aaaacgctgg attcacaacc tcttttattt caaataacca gtaaatacaa
    60001 tgaacatcta caaaaaactt ctatttattt atagatttcg tcaggcaaat ccaattctct
    60061 cttatcaatc aaagtctgat accacgaagc agattttttc aatgttctgc ttcgttcatc
    60121 gttcaattcg attcgaacta atccatatcg attcttaaat gcattcattg gtgacacaca
    60181 gtcagtgaat gcccataaca tatagccttc gcaatttgcg ccttcttctg ttgctttgat
    60241 caaataacgc aaatgctgtc cgataaattc gatacggtaa tcatcttgca cgattccttt
    60301 ctcatccata taccgttctt catgttctct tcccataccg ttttctgtta tcagccaagg
    60361 gatattatga taattttctt ttagatacat ggctatatca tacatgattt tcggatagat
    60421 ttcccatccc ctggaattat tcattttctt cccaggtaaa tcaaagactt cataatatcg
    60481 ttctggatgg aaaggtgtct cttcattcca ttgataacga ggagcgcgaa cgcgtttagg
    60541 ataatattga ttgattccaa ggaaatctac tgtatgatgc tgaatcgttt ctaaatcctc
    60601 tgttgcagga tcgaaataaa tcgattgttt ttgacacaac tccaggaact cttctgtgta
    60661 gtaccctttt accatcggat caaaaaatac tcgattataa aacaaatcat acatataagc
    60721 agctttttgg tcttctggag aattagatcg agcatagacc atttcaggat ttaaaataca
    60781 gccaatcctt ccaccataat ttccgctgcg gtaaatctct actgctttag ccgttgctaa
    60841 aactttatga taattccaca tcatccactt ttttgtgttt tgttcatgcg gccagcgaac
    60901 agcatccaaa tagcaacgcg tttggggaac gattggttcg ttgaatgtaa accagttttt
    60961 taccctatca ccgtaacgat caaaggcaat ttgagcatac ttagcataaa aatcaactac
    61021 ttttcttgaa gaccagccat catatttttc caaaagaaaa gctgggactt cataatgttc
    61081 caaacaaatc atcggttcta cgtctgcttc gatcaaagag tcgatcattt cacttatatg
    61141 ctgagcatat tcttcatcta ctatacagtt ctcataatca gtaaaaaaac gagcccaatt
    61201 gatagaagtc cgataatgtg tcagatggat ggatttcatc agatccacat cctgctggta
    61261 ttgttccata aaattagttg ctacggctgg gccataccca ttatgccaaa caaaatgttc
    61321 atttttatac cagctatcta taaacgaatc ctgtccttct ttttttcctt tccaaccttc
    61381 cgtttgccaa gcagaagatg cagcaccaag aataaaattt tttggaatag taattttcat
    61441 gatttcctcc tgtttttaga tcccatcatt ttccacacga tttgctactt ttacaaatgg
    61501 cagatagatc aaaatagaaa caataataca aacaagttgc gtaataactg caccgatatt
    61561 tcctgctgtt gccagataag cattgacgat cggcggcatt ggccaaggga ccattacaac
    61621 tgctttcgcc gcaaacccta aagcggttgc aaaataacca atcgttcctg tgataagagg
    61681 cgttaagata aacggaatag ctaaaattgg attcagcatg atcggcatac caaaaataac
    61741 tggttcatta atgttgaaga tcccaggagc aagggataac ttggtgattt gtttcatatc
    61801 ctcccgtttt ccaactaaca atactgcaat cagtaaaccg atcgtgactc cagacccacc
    61861 catactcata tacatatccc aaaatggcat agtaataatg ttcggtactt cttttccagc
    61921 ttcaaaagct tccgtattta cagcaattgc cgctaaaagc aacggttccc gtatcggctt
    61981 caccatttga tttccatgga taccaatcac ccaaaagact tgcgcaataa acatcaatag
    62041 caaaataccc ggtaaccctt gaacgacacc ttctaatggg cgttgtacga cattgtaaat
    62101 gatatcataa aggtacattc ctgtaagttc tttgatgata aatcccgcag ccgcgatacc
    62161 cgatacagtc agaatcgtcg ggaataaagc agaaaaacta gcagaaacat tcgttggcac
    62221 ggtatcaggc attctcagct gtagtttctt ctgtttcctc aaccagcaat aaagttcaat
    62281 agaaaggatg gagaccaaca ttcccaaaaa taaccctttc gtgtctgtat attgtttagc
    62341 caatacgttt tctactataa cagtctgatt ttcattcact aattcataaa cagttggatt
    62401 aacagataaa taagacatca ctgcgatgat accagggaat acaccatcca ctttattcag
    62461 cttggctaat tcgatcccta ttagaaaaac agcatagatg gtcaagaaac ttagtgtgac
    62521 atagctgatg gcagatgcga taggctttaa ttcttctaaa aaacgcaagt aacttatctg
    62581 tgctaagcca ttttccgagt caaagaccat tgctgaaaac aatgtgccaa aagcacccgt
    62641 aataattacc ggaatcaatg cagcaaatgc gttttttatc accatgatat accttaaatt
    62701 attgattctc gttgccacgt tccctaaaac tttggctaat ttatccataa aactcattcc
    62761 agatcccctc attcctgctt cttctccttg acgtcatctc tttttgtcta ttagtcagcg
    62821 cttacatttt ggtgaacaga aactatttac tcctcttttt taccaaatat aaaacaaaaa
    62881 atcatctgat gtatttatca taaaatacat cagatgaact gtcaattagt ttctttttct
    62941 cctattattt tctgtaattc tctccgattt attgccatat ggacagtcat tgcgtcaaac
    63001 gcagcaagta cgttccgcct ttcgatggcc tgaacgatct ctgtatgaat atcgatcgtc
    63061 tcgattttca gatgctggat atcataattt ttattaaaca aagcaatcga ttcattaatg
    63121 attgggataa tatgcagcaa ggctatgttt ccgctagctt ctgcaatcat cgtatgaaaa
    63181 tcgatgtcta attgaacatg ttcttgtgtg ccttctcgaa aagaagtttc aatcttttgc
    63241 gttaattttt tcatttggac gatttgattc ttcgttgcat attccgctgc caaacctgcc
    63301 atcttaggct ccaataaata tctcagttca aataagtctc gtatcatccg atcctgatct
    63361 tcaatcaaag aaaaaccgag tgggtcattg gcaatccctc gcttatcact gacaaatgtc
    63421 cccgctcctt gccgaacttc aaggatattc ctggaagcta gagcccgcac agcttctcgc
    63481 accgtgcttc gccccacctc taaataatcg gacaattcat attcattcgg cagtttatct
    63541 cctacttgca actgcatttc ctttaaatat ctaaggatct tgtcagtagt tacttctact
    63601 agggttttat tttcttccaa accacatacc tccttttcat ctgatgtatt ttttcgtaat
    63661 tattataaca cgtttgaatc atctgatgat tttttgtata aaaaatcgat taatccgttc
    63721 atagacatac aaacgaagaa gatatttacc ataaaaaaga ctaggataaa attcactcct
    63781 agccttcgat catttttatt ttgatcgaca aaaaatatga tgttcaataa cagacgatct
    63841 tcattcgatt cttgatgtca tcttttgttt tttttaatat atggataaaa agtttgatta
    63901 catcgtttct attctagaat ttggtcgatt ctcaattctt cttctggtga gaaatctaaa
    63961 ttatccatca ttcgaacact ttcttgtaac tgacttaacc gacttgctcc gatcagtaca
    64021 cttgtaacag atttttgtcg taaattccat gcaagggcta tttgcgctaa tgattgtcct
    64081 cgtgatacgg cgattgtttg cagtgctttg attttttcca gagttgatcc aacttgttct
    64141 tctgaaagga atggtatttc cttacgatgt gctctagaat cttcaggaat accatgtaga
    64201 taacgatttg tcagcaaccc ttgagcaagc ggactgaacg tgattgcccc tagcccttct
    64261 tcttctaata ctggagatag atcgtcttct agtagtgcac gagaaaacat attgtagcgc
    64321 atctgatgaa taatgaacgg tgcttccttt ctttttaaaa tttcagtcat ttttttgtat
    64381 cttctccatt atagttggat ataccaatat ataatgcttt tccttgtctt acaagttgca
    64441 tcaacgcttc tgctgtttct tccaaaggtg tatcagggtc tgggcgatga tgatagaaga
    64501 tgtcaacata atctagcccc attctttgga aactttggtc acaacttgat atgatggatt
    64561 tacgagagcc ccattcccca tatggccctt cccacatatg ataacctgct ttgctagaaa
    64621 taatcagttc atcacggtag gcttgaaaat cttctctaaa aatacgccca aagtttttct
    64681 ctgcagctcc agcagggcct ccataattat tcgcaaggtc gaaatgggta attcccatgt
    64741 cgaatgcgcc tcttaaaatc tctctttgat tatggatagg atcataatca ccaaaatttt
    64801 gccataatcc gagaggagag ataaaatcgg taatttcaaa cctgaatgac cggatttacg
    64861 atattccatt ttttcataac gtgcactatc tgcaatatac aatttttctc ctcctcatca
    64921 aatcttttta aaacgctttc ttgttttcta tttttagttt actacatttt aaagaaaagg
    64981 agttaatcaa aatgattttt tcgtatattt ttttgccatt tgttttttac tcgttgatag
    65041 atcagaaatt gattacgtgc ttgctggatt tttttatagc gtttcggttg ttttttgtaa
    65101 aattgctgat gatagttttc tgctggccaa aacgtaccgg ctggttcgat ttttgtgacg
    65161 attggttggt ggaaagttcc tgaactgtct agtttctgtt ttgattgttc cgctaattct
    65221 ttttgtcgtt cgtcttgata aaaaatcact ggacgatatt gcttccctct atcttgaaat
    65281 tgtccaaatg tatctgtggg atcagtaatt tgccaataga ttgtcagcaa ctcgctataa
    65341 cttatttctc ttgtgtcata aatgatctcc acagcttcca catgacctgt gtaaccacca
    65401 cttacttgat cataattcgg tttttcaaca tgtccgcccg tgtatcctga caaaacagat
    65461 aggatccctt ttttcgattc aaacggctcg accatacacc agaaacatcc ccctgcaaat
    65521 actgcacgtt cttgatagtc agcatcttgc atggcatgct tggaaaagtc atatttttgc
    65581 tccttatcaa atccttccgt aatcaataaa taaaagtcca ttacatcagg cgtcagattc
    65641 attcggatag ctaatggacg tagtgttact tctagttttg ataactgttc tttaacggat
    65701 atattttctc ttgtgtcatt ctttgtctga atcaatactt ttcgttccca atctcgtgta
    65761 ttcggattca aaatcagatt ataaagtgtt tgaatgaata tttgttcctc atccatagat
    65821 tctcctcctt tccgaagaag acaagctagt gactttagct gtaatttatc ataaagtgag
    65881 gaaataatcg attgaatcgt atttattcaa agaagataag cagcttcaga tgatataaga
    65941 tgatctttat cttaaaaagc atactctatg gtttggttta actaaaaaac gacctctgaa
    66001 aaaagggatg ttctccaatt ctcagaagtc gagtaaagat gattcttttt tatgagcgat
    66061 aataaacttc atccaaaaac agaccttgtg cagggacggt ttctcctgca tgttgccgca
    66121 ctttgctttc aaatatttca tcgattgttt ctatcggcat ggcacctgtg ccgatttcta
    66181 gtaatgtccc catgataatc cgcaccattt tatataagaa tccgtctccg acaaaagtaa
    66241 aatgaagcat ttctcccttt cgttcgatag ataattcatc aatcgtacgc actgtggatt
    66301 tttttgattt tttcaatgca gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc
    66361 aagctgcatt cagcttgtcc atatccaact cttgagggaa ataaaagctg tggtttcgct
    66421 caaatgctga aggaatcacg ttgttccaaa cataatagct gtattttttg cccaccgcat
    66481 tatatcttga atggaagcgc tcaggcattt cttcgattct tttgatgaca atatcccgcg
    66541 gaaggtaacg attcataaag tcgatcattt ctgccagtcc aatttctgtg tttgttttaa
    66601 aatttgctac ttgtcctcgc gcatgggtgc cagcatctgt tcttcctgat ccaataattt
    66661 ctatctcttc atttgtcatc tgatgcaata ctttttcgat ttttccttga atggttttat
    66721 cgtcatctcc aagtctttgc catcctgaat atctttttcc gtcatattcg attgtcaact
    66781 tgatgtttct catattttag tggctcctct gtcttccatt tggtcttctc tctacctttt
    66841 taagattgta gcacaaaata tagctccttg cttctctaag acagaagcta tacaagaaaa
    66901 ctgtggaaat atatatttca gaaaaacaaa aaacagccac cggatgaagt atccgctgac
    66961 tgttcaattt gacggctcaa gttttactgt ttgagatgca agatactcaa ccaggcaatg
    67021 ggcacataat taaagaaaaa actgattctt tggcaaaaac ctattttatt cagtaatggc
    67081 caagaattta tagaaggaat tcttgccagt ccataaatcg ccgcaaaaag caaactgatc
    67141 acagacagtc caaggtataa gtggcttacg tccatttgcc cattttttcg atagatcaag
    67201 aaaagaagaa ctggaaacaa taaaaaacca ctgtaaccta aacctgatcc gatattatgg
    67261 acccatgtcg agacattcca cgaagattca tgggtattga tactgaacaa acctgtaaag
    67321 atacaatcac ctataccata gaacgcgatg gctgctgtaa ctagggtagc taacacacga
    67381 gatgtactta caaatgcagc atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa
    67441 accacagacc aaataagaaa cgcttttctt acaggactgg aaacctctcc aaatacactg
    67501 atcacgctct tcatttgatc taattcagga taatacaatc ctaatacgta cggagtcaaa
    67561 aaatcactca gcacgcctaa taataaaaag aaaaaaccaa atttacgtaa aaaatccatg
    67621 atacgcctcc aataacaatt acctatgctt ttaattgtta ttataaacga ctttatcttg
    67681 atttaacaga aacctctatt tacacgaaca tctatataac tcattaaaaa ctcgaatcat
    67741 tttaaaaata ctaaatatct aacgttcaac gttcacttaa tccatctaaa caatctttca
    67801 atttgatttt ttccccactt cttttacgcg cgcctagctc tcctattgca gtaaacaaca
    67861 gatcacttga cgaatttaag gcagtttcca ttgaatcctg gataacaccg ataataaatc
    67921 caataccaac gatttgcatc gcgacatcat tagagatacc aaacaaacta catgctaatg
    67981 gaatcaataa cagtgaaccg cccgcaacac ctgaagctcc acaagcagct aaagcagaca
    68041 aaatacataa aaggactttc aaaacaaatg gtgcttcaat ccctaaagaa tgtacagcag
    68101 tcaacgtcat caaggaaatg gtaatcgcgg caccgcccat attgatcgta gcacctaacg
    68161 ggatcgatat ggaataagac tcttttgtca atttcaatct ttcagccaac atcatgttta
    68221 tcgggatatt tgcggcagaa cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac
    68281 aaaagaaaat caatggatag ggattttctt taataaacaa aaacgtgagg aatgggtaca
    68341 caactaatgc gacaaacagc atcgtaccga tcaaaacaag taaaagctgc agatactctg
    68401 ccaatccagc gattccagtc gtagcaattg attgataaac caatcctaaa atccctatcg
    68461 gagcaaatgc aataatcact tgtacgactt gtgacaacgc tatagatatc tgatccacca
    68521 actcttttgt cgattctgaa cgtgctcgaa aagctagtcc caacaataca gcccagaata
    68581 aaacgccaag gtaattcgca tcaataagag attgaacagg attttgtgtg acattcgtca
    68641 acatagtaga taaaacactt tccaaacttt gcggtgcttt ttcagatact gtttcttgta
    68701 aagtaatagg aacagtaaaa attgaactta caatgactgc tacaagtgca gaaagcaatg
    68761 ttcccactaa atataagatc aaaataggct tcacgaatgt cttattccca attttatgct
    68821 tggcaattga cgccatcgtc aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac
    68881 tgacaaacaa cgtccccaat attgaaataa atgtccacgt ggggaaaaag ataccaaaca
    68941 atattccgac taaaatacca acaacaatac gttgaactaa cgacatatcc aaaaacttct
    69001 ctaacaaatg accacccttt cacaatttta acaatcattg tatcatttta tctaaagaaa
    69061 ctaaaggtgc aattttctaa aaattctaat aatacaattg gcaattcatg ctcttgcaac
    69121 attcaatttt agtattggag ggtttattca atctctaaag aagtcgagag aaaactattt
    69181 atcgttatta ttatagttat ccaagtaaaa cgtaactaag atgaaggacg aaactagaaa
    69241 tttcatcctt catcttaatt cttagacata gcaatcaatt aatattttcc actgagtctc
    69301 ttctttctct cactctcact ggtttactta cccataaacg atttgattaa agccattttt
    69361 caattcatta ttcgctgtct cgttaaagta aagataatta tcgggattcc cctgattttg
    69421 ttgtgtcacc aatacttttg gctgattttg ctgaaacccg aatagataga cgttcttttt
    69481 cagatatggt tctgtctctg catcggaata gacggctgtg atttgatagt ctgcttgacc
    69541 tgtcccactt tctgaccatt ctgcagaaac aggcactcca ccaatagcca tcttccactc
    69601 cccgttcaaa ataacttgag ggactttaag accatataag tccacactca tttgattcgt
    69661 atagcttttg tattgttgtc ccattgtttg gccccatgta gccataaatg cctctaattg
    69721 tgcggatttg tctgcattcc acagtgtttg ttcgacttgt tcgctgcttt ctgaagatga
    69781 agcctctaca gaagaacttg aagtagatgt ttgagttgtt tcagtcgttt tggaagactc
    69841 tgacgaagta gaggtatctg ctgtttccgt acttgctgca gttggcttgc tctctgtgct
    69901 agttgttgta gtagttgcaa ttgttgcttt cgctgtttct tttgttgatt cttttttcga
    69961 ttcattcccg ttggtacaac cagctaacaa aaaagctaga ccaattgtta ctaaaatcct
    70021 ttttttaaat taaaaaactc ctttcgatta ctcccacttc tttattctat caaataagca
    70081 atgtgatttt attgattttt tgtattttct catccatctt ttaaaccttt taaaaactaa
    70141 gaagcacccg ctgatgttgt ctgtaataca tcagcgggtg cttcttttat tttaatcttc
    70201 gtgattttcc aatttacctc acgctttata tttgtatttg aagaaacata gacttttagt
    70261 catcatcgtc ttcctcatcc aaatcttgtc ggacagtttt tccttggagt ctttgtactt
    70321 ggtagatgat ttctttattg aaacttaaaa gttcaacaag caattgtttc aagccatatt
    70381 tttcttcttt ttcagctaat ttgattgccc gtgtgataaa gacattttgg aaatcaaaat
    70441 cttttgcaaa gttttccaac attgttgagg ctggtaaata tttgttttga ccatgttcgt
    70501 aaatttttcc ataacgcatg acttcttcta aagtagacgg aacgatttca ttttcaatca
    70561 ctaactcatg agagatttta ttgaaccatc tcgcttcttg atcagcatat tctgaaaaaa
    70621 gggtacttaa ttcttgcgaa gatgtaccca aaacatacaa ttgtgcttgg atcaatttca
    70681 tttcttctaa tttaaaattt gccaatacat gccccaccat ggcgccagca gttggtttat
    70741 gatgatcgat atctgcttgt tttgtttctt gagcaaattt ttcttccact atattcactg
    70801 atttacgcct cttttacttt tgttgattgg acttcataac ctaatttttc cacaactgca
    70861 gctaattgtt cagggtggac ttcatctgga tcaaagtttg ctttgatttt gctcgcatta
    70921 aacaaaactt tcgtattgct taccccaggc tgttgagaaa ccgcatgttc tattttttgc
    70981 atacagcttg gacaagctag tgtatctaat tgcataatca tttttttcat cgtagttctt
    71041 ccttcctttt tcttgatagt cttattctag attacagctt ccataaaaaa attgattctt
    71101 atcaagtttt acgatttttc ttctttgctt tcgtgtccaa aatacaataa acgcatcgcg
    71161 ttaaagataa cgatcaagat actagcttcg tgaacgaaca tcccactagc catgtaaata
    71221 aacccggcaa ataagccgat gagtaaaaat aagacgacac caatggcaat cactacattt
    71281 tcacgggtat tcaaaacagt tttcttagcc aaacggtaag catgaaccaa cgatccaaaa
    71341 ctagattgca tcaagacaac gtcactcgtt tcgatagcga catccgttcc tgatcccata
    71401 gcaatcccga tatcagccgc agccaaagag ggagaatcat tgattccatc tccaatgaaa
    71461 gcaacgtgca atccttgttc ttggtatttt ttcacaaatt gaaccttttc atctggcaat
    71521 aattcagcat ggacttcatc aatgcctaac atatcagcta cataatcagc agtcatctga
    71581 ttatcacctg tcagcatcac taaatgtttt gctcctgctt gtttcaacat agctaattgt
    71641 tcagcgactt ctggtcgaat cacatctgac acaccaatga tttgagtgat ttttttgtcg
    71701 attgctacaa taatgactga gctgcctctt tgttgtaatt gatgtaaatc ttgtacttgc
    71761 tttggtgtga gagaaagttt gtgagcggca atcaatttgg tgttgcccgc acaaactgta
    71821 tgaccatcaa tctcagctgt gattccttgt cccttgatcg tctgattatc tttgactgct
    71881 aattgttgaa aatcaatgtc tttctcctga gcataatgga tcacggcgcg ccccagagga
    71941 tgatcggata acgtttctaa tcgagccact aaagctaagc tgtccccttc atcctctgta
    72001 tagttcttga tagtggatac agcagtagtt cctttggtca atgtaccggt tttatcaaag
    72061 acaaaagtat cgattttgga aaaagtatcc attgcttcac cgcctttgac taagatgccc
    72121 cgtttcgctc cattaccgat tcctgctaca ttcgaaacag gcgcaccaat gactaaagcg
    72181 ccaggacaac caagaaccaa aacagtgatg gctaaacgaa aatcacgact gatcagacca
    72241 acaagcaacg caataagtaa aacggttgga gtataatact gagaaaattg atcaatgaat
    72301 ttttccgcat gtgatttggt atcttgtgct tcttcgacta attctataat tttggcaaag
    72361 gtcgtatcat ctccgacctt agttgcttcg atcgtcacgt agccatctgc taaaatcgtt
    72421 ccagaaaata cgttatctcc actgattttg acgacttgtc gtgattcacc cgtcactgcg
    72481 gcttcatccg catacccttt cccgtcaatg actcgtccgt ccacaggaat agctccacca
    72541 gtttttacta agacgatatc gccttcttcc acgtcatcga tttccacttc ttcggtcgtt
    72601 ccatcttctt ggacaacgct ggcagtcgat ggggccatct cggtcaaagc cttgattgat
    72661 tcccgcgttt tggtcaatgt tttttgttcc agataactac caaacaaaaa caagaatgta
    72721 acgatagctg actccttgta ttctccgatc ataaaggcac caagcacagc aatagtaacg
    72781 agtaaatcaa ttgagataac tttgactttt actgcctgat acgcatggat tataataggt
    72841 atgaccgcaa taatagaagc tatggctaga gcaatgttat agaacaagac aaatccagta
    72901 aatttcccga taaaaccaaa aataatcaac acagctgata aggcggtgat atgatttcga
    72961 tgctcttgga tccacttttg taatttcatc tttctccctc ttttcctttt cattcttacg
    73021 agactaagta tagatactta tccatcataa aaaattgacc actatcaagt ttattcaaaa
    73081 aggcggtttt cttttggtat actgaattcc tacagtcatt aaacgatcat atagaaaaag
    73141 gaagcgccga aacgcttcct taggtagttc tattttttta ttcaaagata agatgctttg
    73201 tcatcttacg actgaagaac aacaatcaaa aaagggcagc agccactcat tcacaagaaa
    73261 tatcgttttt tgatatggga attgaagcag tggacaaata tctctactta ttagctggga
    73321 ataagatcca aaaaagctta atggatttta tccaagaatt ggaatgtact ttccacaaaa
    73381 aattcactca ttccattctt ttaaaacttt tgattcatac agcgtgtcta attgagcgta
    73441 cattgataaa cggtcatgaa cttaaaatta tatcagaaga tgacacaaga ccttctcatg
    73501 aaacaatttt tcatgtaaaa aaggccttca aaaatattga aacagaattt gggatcactg
    73561 tttcttatga tgaatgtttc tttatctatg atattatcgc atctaaataa tcttttttta
    73621 tgtaaacgag tattttttta acttattgtt taagagtgat acgcgaattg taaaattaag
    73681 ttagaaaaat aaaaaggcat ttatggtaca ctcaaattgt atttccgacg aaagaaaaca
    73741 aaggagtgt
//
LOCUS       DAIGUC010000004        72489 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.004, whole genome shotgun sequence.
ACCESSION   DAIGUC010000004 DAIGUC010000000
VERSION     DAIGUC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.004"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            106..771
                     /locus_tag="NOB46_000221"
                     /pseudo
     CDS             106..771
                     /locus_tag="NOB46_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
     gene            918..1283
                     /locus_tag="NOB46_000222"
     CDS             918..1283
                     /locus_tag="NOB46_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HCI1057200.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(1431..2639)
                     /locus_tag="NOB46_000223"
     CDS             complement(1431..2639)
                     /locus_tag="NOB46_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1057201.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(2658..2936)
                     /locus_tag="NOB46_000224"
     CDS             complement(2658..2936)
                     /locus_tag="NOB46_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057202.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            3090..3785
                     /locus_tag="NOB46_000225"
     CDS             3090..3785
                     /locus_tag="NOB46_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI1057203.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(4227..5024)
                     /locus_tag="NOB46_000226"
     CDS             complement(4227..5024)
                     /locus_tag="NOB46_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HCI1057204.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(5021..6205)
                     /locus_tag="NOB46_000227"
     CDS             complement(5021..6205)
                     /locus_tag="NOB46_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI1057205.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(6230..7477)
                     /locus_tag="NOB46_000228"
     CDS             complement(6230..7477)
                     /locus_tag="NOB46_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI1057206.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            7692..9437
                     /gene="dnaX"
                     /locus_tag="NOB46_000229"
     CDS             7692..9437
                     /gene="dnaX"
                     /locus_tag="NOB46_000229"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCI1057207.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            9457..9771
                     /locus_tag="NOB46_000230"
     CDS             9457..9771
                     /locus_tag="NOB46_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCI1057208.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            9796..10392
                     /gene="recR"
                     /locus_tag="NOB46_000231"
     CDS             9796..10392
                     /gene="recR"
                     /locus_tag="NOB46_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCI1057209.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            10456..11100
                     /locus_tag="NOB46_000232"
     CDS             10456..11100
                     /locus_tag="NOB46_000232"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCI1057210.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            11115..11444
                     /locus_tag="NOB46_000233"
     CDS             11115..11444
                     /locus_tag="NOB46_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HCI1057211.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            11458..12396
                     /gene="holB"
                     /locus_tag="NOB46_000234"
     CDS             11458..12396
                     /gene="holB"
                     /locus_tag="NOB46_000234"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCI1057212.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            12432..13256
                     /locus_tag="NOB46_000235"
     CDS             12432..13256
                     /locus_tag="NOB46_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCI1057213.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            13249..13596
                     /locus_tag="NOB46_000236"
     CDS             13249..13596
                     /locus_tag="NOB46_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HCI1057214.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            13665..14537
                     /gene="rsmI"
                     /locus_tag="NOB46_000237"
     CDS             13665..14537
                     /gene="rsmI"
                     /locus_tag="NOB46_000237"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCI1057215.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            14646..15767
                     /gene="dinB"
                     /locus_tag="NOB46_000238"
     CDS             14646..15767
                     /gene="dinB"
                     /locus_tag="NOB46_000238"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCI1057216.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(15821..16423)
                     /gene="nrdG"
                     /locus_tag="NOB46_000239"
     CDS             complement(15821..16423)
                     /gene="nrdG"
                     /locus_tag="NOB46_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCI1057217.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(16738..18927)
                     /gene="nrdD"
                     /locus_tag="NOB46_000240"
     CDS             complement(16738..18927)
                     /gene="nrdD"
                     /locus_tag="NOB46_000240"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCI1057218.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            19226..20020
                     /locus_tag="NOB46_000241"
     CDS             19226..20020
                     /locus_tag="NOB46_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057219.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            20010..22052
                     /locus_tag="NOB46_000242"
     CDS             20010..22052
                     /locus_tag="NOB46_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057220.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            22333..22482
                     /locus_tag="NOB46_000243"
     CDS             22333..22482
                     /locus_tag="NOB46_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HCI1057221.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            22493..24007
                     /gene="dltA"
                     /locus_tag="NOB46_000244"
     CDS             22493..24007
                     /gene="dltA"
                     /locus_tag="NOB46_000244"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HCI1057222.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            24004..25209
                     /gene="dltB"
                     /locus_tag="NOB46_000245"
     CDS             24004..25209
                     /gene="dltB"
                     /locus_tag="NOB46_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCI1057223.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            25254..25487
                     /gene="dltC"
                     /locus_tag="NOB46_000246"
     CDS             25254..25487
                     /gene="dltC"
                     /locus_tag="NOB46_000246"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCI1057224.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            25490..26758
                     /gene="dltD"
                     /locus_tag="NOB46_000247"
     CDS             25490..26758
                     /gene="dltD"
                     /locus_tag="NOB46_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCI1057225.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            26899..27981
                     /locus_tag="NOB46_000248"
     CDS             26899..27981
                     /locus_tag="NOB46_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCI1057226.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            27981..28784
                     /locus_tag="NOB46_000249"
     CDS             27981..28784
                     /locus_tag="NOB46_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI1057227.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            28854..29594
                     /locus_tag="NOB46_000250"
     CDS             28854..29594
                     /locus_tag="NOB46_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1057228.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            29605..30609
                     /locus_tag="NOB46_000251"
     CDS             29605..30609
                     /locus_tag="NOB46_000251"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCI1057229.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(30654..32498)
                     /locus_tag="NOB46_000252"
     CDS             complement(30654..32498)
                     /locus_tag="NOB46_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057230.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            32710..33228
                     /locus_tag="NOB46_000253"
     CDS             32710..33228
                     /locus_tag="NOB46_000253"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI1057231.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            33356..34039
                     /locus_tag="NOB46_000254"
     CDS             33356..34039
                     /locus_tag="NOB46_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCI1057232.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            34348..34421
                     /locus_tag="NOB46_000255"
     tRNA            34348..34421
                     /locus_tag="NOB46_000255"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34382..34384,aa:Arg,seq:tct)
     gene            34580..34939
                     /locus_tag="NOB46_000256"
     CDS             34580..34939
                     /locus_tag="NOB46_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HCI1057233.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            35062..36693
                     /locus_tag="NOB46_000257"
     CDS             35062..36693
                     /locus_tag="NOB46_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HCI1057234.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(36755..37396)
                     /locus_tag="NOB46_000258"
     CDS             complement(36755..37396)
                     /locus_tag="NOB46_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI1057235.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    37582..37658
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            37678..37986
                     /gene="rplU"
                     /locus_tag="NOB46_000259"
     CDS             37678..37986
                     /gene="rplU"
                     /locus_tag="NOB46_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCI1057236.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            38013..38357
                     /locus_tag="NOB46_000260"
     CDS             38013..38357
                     /locus_tag="NOB46_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCI1057237.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            38370..38663
                     /gene="rpmA"
                     /locus_tag="NOB46_000261"
     CDS             38370..38663
                     /gene="rpmA"
                     /locus_tag="NOB46_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCI1057238.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(38756..39904)
                     /locus_tag="NOB46_000262"
     CDS             complement(38756..39904)
                     /locus_tag="NOB46_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1057239.1"
                     /translation="MAMIKQYKKKNGEKAWYFKTYLGIDPLTGKKKYTTKRGFRTQKE
                     AKTALSRLELELQKTGMPTSTNTTFKEAAELWLESYKKTVKESSYSRTKIIFNKHIYP
                     KFGNIKLSKINTAYCQKVVNDWSEKGTSKQYPLFINYMNKVFKYAINIGLTSDNPTLN
                     LLIPKPQIKTEKKLKLYTKEQLELFLNEVSQEQNPYFKNRDYTLFRLLAFSGCRIGEI
                     LALTWDNINFKTNEMAIKKTVARSDKYYISETPKTKKSNRIIYLDEKTIKQLKFWKLE
                     QRKYLFQLGFTKANYLFTNDENNFTINQSVAERYNIYRERAGLPYIGLHGFRHTHASM
                     LYEAGADHKEVQERMGHANIKTTMDTYTHITNSKKEETTQKLTNYINF"
     gene            complement(39916..40227)
                     /locus_tag="NOB46_000263"
     CDS             complement(39916..40227)
                     /locus_tag="NOB46_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057240.1"
                     /translation="MIYPEFKEWLEKNTIGYETFIIKATNYQIEKNKNRPPKKRWDDK
                     KIDKAVLEMWKQVVTNLYQTIRKEKGVPLINGKEIWLEFIEEQGLIEFFNDSMAELEF
                     E"
     gene            complement(40281..40676)
                     /locus_tag="NOB46_000264"
     CDS             complement(40281..40676)
                     /locus_tag="NOB46_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI1057241.1"
                     /translation="MIINELGVKVEEKEHLDADGHYIACMNTIVIKANLSKYRRQRTL
                     LHELGHASKHHDNYFLYNLAFSLHSKMEYEADRFMIENLLDSYIAKSELEPHNINYMK
                     FIEDNNLSVRFEPLVKELLKARIYCYVAL"
     gene            complement(40712..41059)
                     /locus_tag="NOB46_000265"
     CDS             complement(40712..41059)
                     /locus_tag="NOB46_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1057242.1"
                     /translation="MTTFERVKMLADKRKISIVELEEKLNFSKNSLYAWKKSKPSIDK
                     LNAVADYFNVSTDYLLGRTDDPDIGVAPEERKLTVEEALASVMSSDGKPLTDNDREIL
                     SAMIEAYLEKKDN"
     gene            41358..42068
                     /locus_tag="NOB46_000266"
     CDS             41358..42068
                     /locus_tag="NOB46_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016024367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HCI1057243.1"
                     /translation="MTNLVIMKDQQAVTTSLQVAEVFGKEHKVVLKAIDELKEGVAQN
                     YADLFYEDTYIHPQNKQKYRQIIMNRDGFTLLAMGFTGKKALQFKLQYINAFNEMEKT
                     IKEKSVSIPTTKRGLALLALEASEETNQRVDVIEQEVFDLKENQPLPQGEYSIISSRI
                     NKRVYEVADAYSINRSNRKTIGLLFKDINSGVKKISGVGARTQLRAKHYEKVMDFINS
                     WEPSSVTKFELRQTRMDV"
     gene            42081..42293
                     /locus_tag="NOB46_000267"
     CDS             42081..42293
                     /locus_tag="NOB46_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1057244.1"
                     /translation="MSQDFILKVRVALATHDKSQAWLAEQLDISTAYMSDIMNGRRKP
                     DKQIKPIEAVLAELEKEKNYANNNSR"
     gene            42271..42555
                     /locus_tag="NOB46_000268"
     CDS             42271..42555
                     /locus_tag="NOB46_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057245.1"
                     /translation="MQITIPDNLVVSELTTQITNAVLNSLDERLRLMNKSVELPPYPN
                     KSEVKKVLGIGDDKLTHWINLGLKTQQWSKLDIRIERSELQRFLKENFEF"
     gene            42576..42764
                     /locus_tag="NOB46_000269"
     CDS             42576..42764
                     /locus_tag="NOB46_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057246.1"
                     /translation="MSYTLQQEHQTLRLIKQRRKQLQDDREALRKADELPDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            42761..42934
                     /locus_tag="NOB46_000270"
     CDS             42761..42934
                     /locus_tag="NOB46_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057247.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            43090..43431
                     /locus_tag="NOB46_000271"
     CDS             43090..43431
                     /locus_tag="NOB46_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057248.1"
                     /translation="MENELSTLDQYLADPDWGKSNSKETNNRKIRRNLLTNEELACDQ
                     DDLGNFVSIWDHVYLIHLSKHSNKPEYIYVAEDGLIDALEEYERDNLIDISYYGQGKK
                     YIAEMEAEFDE"
     gene            43424..44170
                     /locus_tag="NOB46_000272"
     CDS             43424..44170
                     /locus_tag="NOB46_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI1057249.1"
                     /translation="MSEKEQPLKNRSDNTLFNSLYKINVKGVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYRDPETHRPYLFDEKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            44176..44862
                     /locus_tag="NOB46_000273"
     CDS             44176..44862
                     /locus_tag="NOB46_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057250.1"
                     /translation="MFKPLIDSYSAVLRRFKGNQIVARINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRSISLK
                     DESSSTVSDANVLANIILDFIFEHHIPFKEGYEILPGNQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLNIGG"
     gene            44881..45696
                     /locus_tag="NOB46_000274"
     CDS             44881..45696
                     /locus_tag="NOB46_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI1057251.1"
                     /translation="MSDKQKKRYYWLKLKEDFFEEDTIEWLEEQPNGKEYCLFYLKLC
                     LKSLKTEGILVRNVGNLMIPYDPESLAKLTNSNTDTVKVAMDLFNKIGLIKILDSGEI
                     YLNQLSELVGSETEYARQKRIQRAKEDNVQKLSGKGRLEIELEKDIDIDIDKEEKKGK
                     YSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYVINWLP
                     TNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLPI"
     gene            45713..46564
                     /locus_tag="NOB46_000275"
     CDS             45713..46564
                     /locus_tag="NOB46_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1057252.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPAHFILSGKSGSGKSHLSMAIAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            46561..46920
                     /locus_tag="NOB46_000276"
     CDS             46561..46920
                     /locus_tag="NOB46_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI1057253.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAQANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            46935..47096
                     /locus_tag="NOB46_000277"
     CDS             46935..47096
                     /locus_tag="NOB46_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI1057254.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            47093..47404
                     /locus_tag="NOB46_000278"
     CDS             47093..47404
                     /locus_tag="NOB46_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057255.1"
                     /translation="MIVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKPMWAEKTK
                     RRTPRRIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK
                     C"
     gene            47398..47688
                     /locus_tag="NOB46_000279"
     CDS             47398..47688
                     /locus_tag="NOB46_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057256.1"
                     /translation="MLDMKIEDYRITSDSRNIVLSKVRRDEEGNIRYTEAKEESRADI
                     GYFQTVSSCLKAIQRDYVLSEERTIKSIIEYKKALENITRQFEQACEIEEEK"
     gene            47688..48005
                     /locus_tag="NOB46_000280"
     CDS             47688..48005
                     /locus_tag="NOB46_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCI1057257.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILDEYME
                     DSK"
     gene            48002..48220
                     /locus_tag="NOB46_000281"
     CDS             48002..48220
                     /locus_tag="NOB46_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HCI1057258.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTALGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            48232..48645
                     /locus_tag="NOB46_000282"
     CDS             48232..48645
                     /locus_tag="NOB46_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HCI1057259.1"
                     /translation="MIPRYRVWDKQTERMHIVSGIDFNDGLVSSVNIWHEGWPWVLEP
                     DEIVLMQSTGLKDKNGVEIFEGDVVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCATVD
                     EDLEYRIFNTELFEEYTYEVIGNIYENSELLEEQR"
     gene            48642..49361
                     /locus_tag="NOB46_000283"
     CDS             48642..49361
                     /locus_tag="NOB46_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HCI1057260.1"
                     /translation="MNKQELIDKLASLVGSIEDFKGISTFHDGKYAGLEHALELIQQL
                     DELQNPVESKITDEQAWNKVAEAYPESAQSLRNTLDNAVFGKTGEPQKHVMPKFFDKW
                     AKQVLEKRDKFYAISLITRAGWGYGVDYELDNGRSPSGTKELLNWIVENEGDDYPNKK
                     KATEALLYGYEVEEEPLYYVKLPVVYFNHLDLETYLMKDDRGNITIADNNDFDDMKFT
                     ESEIKAIDERYWPFAVPVEKV"
     gene            49372..49662
                     /locus_tag="NOB46_000284"
     CDS             49372..49662
                     /locus_tag="NOB46_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057261.1"
                     /translation="MIKKIKTLIDGFLLERKLVKVRELIKIHIDSGERSMYWVATDSE
                     KQNVMNMIRFFEIAFEDGYFATGEYFDASSWMSSNPEEVWQIYLEMKEVAEG"
     gene            49659..49832
                     /locus_tag="NOB46_000285"
     CDS             49659..49832
                     /locus_tag="NOB46_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057262.1"
                     /translation="MSRHLMLHIPDGTKAIAISIVAERKDGGLALTTKGIDTKQILEG
                     RDVEIEINEEEAE"
     gene            49829..50125
                     /locus_tag="NOB46_000286"
     CDS             49829..50125
                     /locus_tag="NOB46_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057263.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFSYPFRGYVEHLYNHSAIIRIENTMKCDKWLAKSKENLAVARLVDIELINDK"
     gene            50202..50618
                     /locus_tag="NOB46_000287"
     CDS             50202..50618
                     /locus_tag="NOB46_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HCI1057264.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            50879..51292
                     /locus_tag="NOB46_000288"
     CDS             50879..51292
                     /locus_tag="NOB46_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057265.1"
                     /translation="MDKEIKANFKLDLTELKELLNKASDQVEQIKYQGMDRERLIDII
                     EQQRLELIQKEAVCKEYKKHLEQVIEYHSVEKYRSVVQKNRATIPDPRQDVSISIKTP
                     VFNSVKSEKLESISTALVEKAAEMNSLANEVSRLI"
     gene            52119..52379
                     /locus_tag="NOB46_000289"
     CDS             52119..52379
                     /locus_tag="NOB46_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057266.1"
                     /translation="MNHEKFIEKCKAIVREKIENEIADLSGAVPEFSVFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            52420..52647
                     /locus_tag="NOB46_000290"
     CDS             52420..52647
                     /locus_tag="NOB46_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057267.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAT
                     PKEIDKCKLLYCGHGYWKDEYIQKNIRRYLS"
     gene            52701..52952
                     /locus_tag="NOB46_000291"
     CDS             52701..52952
                     /locus_tag="NOB46_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057268.1"
                     /translation="MYKKALEIENDRKWVENSITANGETTIEIKPVWGGCYANVDITE
                     IGEGKAVLILTLVSRTLPNLKETVRSYELDGMETIHTSY"
     gene            52982..53437
                     /locus_tag="NOB46_000292"
     CDS             52982..53437
                     /locus_tag="NOB46_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HCI1057269.1"
                     /translation="MSKLNPKQQAFADEYIITGNAYQSALKAGYKENYAKNAQEKLVE
                     KGGKVSDYIQEKLKEVQTKRHLTMEEALAITASIAKGEPQRFEVVKRDPYTNEIIERE
                     VSEYSAGFKERNQALEHYYKINAAFVDKQKVEISEIPTFIDDISSDDDG"
     gene            53430..54728
                     /locus_tag="NOB46_000293"
     CDS             53430..54728
                     /locus_tag="NOB46_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HCI1057270.1"
                     /translation="MAKKLSEFLPPKFHSVWRATLNQDILNIVCKGGRGSGKSSDIAH
                     IVTQLLMRYAVNAVGIRYVDNTLEQSIYEQMKWAIEKQGVSRLFKFNKSPLKITYLPR
                     GNYMIFRGAQNPERIKSLKDSKFPFAIGWIEELAEFKTEDEVTTITNSLLRGELDDGL
                     FYKFFYSYNPPKRKQSWVNKKYETSFQPDNTFIHHSTYRDNPFISKEFLKEVEATRAR
                     NPRRAEWEYDGKAVGSGVVPFDNLQVKKGSITDEMISNFDNIRNGLDYGYATDPLAFV
                     RWHYDKKKNGIYAIDEIYGVKISNREFANKAKSKGYQNEEIFSDSAEPKSNAELVNEH
                     GMKGIKGVKKGPDSVEYGEQWLDDLAFICIDPLRTPNIAKEFENIDYQTDRDGNPKPR
                     LEDKDNHTIDATRYAFNEDMWAKKKSTVTKEQRNKIRRMF"
     gene            54741..56240
                     /locus_tag="NOB46_000294"
     CDS             54741..56240
                     /locus_tag="NOB46_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI1057271.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVSGVEAYKDRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGFRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVIYNKKDETGE"
     gene            56245..57165
                     /locus_tag="NOB46_000295"
     CDS             56245..57165
                     /locus_tag="NOB46_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCI1057272.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGMDELKRQAGILEMTIAEKGYLKL
                     VEHVINSSFRADGFATFSERLWMYQAELKADLDKLLVRSVTMGRNPKQLAPELSKFLT
                     EEGRENTKFNTQRLMVTEITRIQSGVQKESYIDADIEKYGWVTEPNACQLCKSIAADG
                     PYLVSEMEVGKNMMPVHPFDRCSTYPIVDR"
     gene            57325..57927
                     /locus_tag="NOB46_000296"
     CDS             57325..57927
                     /locus_tag="NOB46_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HCI1057273.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQKGNLPAGSQETPPTAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELEAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIRKENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            57940..58863
                     /locus_tag="NOB46_000297"
     CDS             57940..58863
                     /locus_tag="NOB46_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI1057274.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDESVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRSA
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            58881..59144
                     /locus_tag="NOB46_000298"
     CDS             58881..59144
                     /locus_tag="NOB46_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057275.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAVTVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            59156..59485
                     /locus_tag="NOB46_000299"
     CDS             59156..59485
                     /locus_tag="NOB46_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HCI1057276.1"
                     /translation="MTIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFI"
     gene            59482..59808
                     /locus_tag="NOB46_000300"
     CDS             59482..59808
                     /locus_tag="NOB46_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057277.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKAWQQTTARNPAYRNSLIVQEVV
                     LDEGAT"
     gene            59792..60130
                     /locus_tag="NOB46_000301"
     CDS             59792..60130
                     /locus_tag="NOB46_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HCI1057278.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            60130..60522
                     /locus_tag="NOB46_000302"
     CDS             60130..60522
                     /locus_tag="NOB46_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HCI1057279.1"
                     /translation="MIKTRDQSIFDELFKISQEKLGYKTYDYKPLDNVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQVSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            60533..61045
                     /locus_tag="NOB46_000303"
     CDS             60533..61045
                     /locus_tag="NOB46_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HCI1057280.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELNLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            61091..61459
                     /locus_tag="NOB46_000304"
     CDS             61091..61459
                     /locus_tag="NOB46_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HCI1057281.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFIDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEEETITLDEMDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQAE"
     gene            61540..61800
                     /locus_tag="NOB46_000305"
     CDS             61540..61800
                     /locus_tag="NOB46_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057282.1"
                     /translation="MTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQAEKKVGKKT
                     VPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            61817..64639
                     /locus_tag="NOB46_000306"
     CDS             61817..64639
                     /locus_tag="NOB46_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI1057283.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFNAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQRLVVA
                     IGAIAIAIGPILYALGMLVKAFQTMKVGLGVLGNGISLFKKLGSAIGFLTSPVGLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTIQEAPGKAADWIKNKWTETKEFFSSIWDGIKEAASSAWEGIVNILAP
                     YVIAIKNVFQPMIDFFTNLWSQIGSIAGSAWEIIKTAVMGPILLLIDLITGNFNQLKE
                     DASMLWTTLTTNIQNIITTFVDIVVGYYTALKDTVINIWNVLTSTIKDVWNSFTTWIK
                     ETTNNIVNSIRQGWNNLKQGTIDLFNNMIQGAKDLWNSFKAWFINLVIGTKDNIIQGW
                     ENLKQGTIDTFNNLVSGAQEVWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDS
                     FLEGLQNAWKSVQDFVGGIGDWIREHKGPIRYDKKLLIPAGQAIMNGLNAGLTNGFAS
                     VQSNVGNMANMIADSFTRTPDIDLSANLKNANRNFTTQIEHSVNYGKNKRPAVFNIRL
                     GNQVFEAFVEDISNIQGKEADINLLF"
     gene            64657..65439
                     /locus_tag="NOB46_000307"
     CDS             64657..65439
                     /locus_tag="NOB46_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HCI1057284.1"
                     /translation="MEWHNPMYEFRDTVKNDSQKTWIPTSALNYDGKFIENYIEGYQT
                     LYVEGREMVSLEIESEAVSIGVRISSQRLPERILTIHFKLEEKNPIEFQRSFNKLMRL
                     LYRDKDVEIHFNDELDMYYYGRYQTCDDIPGNVHSVISSFSIICSDPRKYTRIFETNG
                     IVSEYLPYEVAPISISLKANNDGNLSITNGRQNISVTNSMIKKGDFIEMDIAEGKVFV
                     NGVNKTRILDLTSSFKNFMVRTGDLIKCDNGTPLIRYRGVWL"
     gene            65439..68327
                     /locus_tag="NOB46_000308"
     CDS             65439..68327
                     /locus_tag="NOB46_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1057285.1"
                     /translation="MDKDVYFFDDSQKLIKIVGEDKLFSVVQEKEITPSKDELINDKL
                     AVSMEFDDEIKESAYMAVRESESSFSMYKIIGIADPGSLLIFTGINFGPDELDAYIIN
                     DIRPANEFFQKTIQRVIDFTLGEWRVGHLDSTLPAVSMTFYYCSIREALKNLQTLGCE
                     IVFRCNLSGEGITDKWIEVYKQIGEYSNERYEYGDKALTIEKEVDRSNIYTSLIGRGR
                     GEEVGDGYGRRIEFDQVYWSKSKGDPLNKPTGQIYLEIPEMTEKYGIPTKNGKRRKRE
                     KVIIFEDCEDPVELIQLTYQELVNCSRPLVQFKATIFGADSLGNIIRIHRDDRGYHYE
                     TRIFSVKIDRLTGKVETGLGDNLNTSSTRQASNTQTAIQTLDEKKMTFYESTEVSKWQ
                     SDIIRGAKGGSIIMMNPWDTGKGESRQPYQMVWMNGDSIETSNHFLVANSEGIGFIDG
                     KFNEANFKTAWTIDGNFNANYIQSGRIRADIFETSFNAVGDQLKLVKGALQIVNSNKK
                     IMELTKKGMEFWNTKESIGTIGTTDSAGNPFPGASTPTPLEDNSLVIRTNGDGKYILI
                     SPKEGKGWVILGNGTSILFGSLNLQEKLNAFGDAEFMKNVNIRGKLTINGQEVFPGQG
                     GSGNNGGGSWNGMYPPELTSQADKFAWELWVMLLSRGYSKASIAGILGNVQGEAGAAM
                     NPDIAQVGGPAYGIVQWDGSAYPLVPPATWDGRTYVQNLMRAAGITEDYRTMSAQGKL
                     LDWTMYNGQWLGIVQPASVSGFKVMTDPAAAAYTFERNYERPATTHPERQGWAVNWYN
                     KFKDLQVPSAGSILSTAKSLMGYFHYSQPLRWNFGSVDNPDRNGYADCSSFVWLALTK
                     AGYKTATRGTLWYTGSMAADARGARQYLTEISPNEAKAGDIIIVNQGAGAGNDGHTAI
                     LAEDWKGYSTSIVEMGGMNSNGVGIGRVDWSFGYLLNGGDVCLVRAKK"
     gene            68338..68856
                     /locus_tag="NOB46_000309"
     CDS             68338..68856
                     /locus_tag="NOB46_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HCI1057286.1"
                     /translation="MIEEKGLNHLKSLLNQPIGNHQCYALSAEYAGVMIGPDMGAGTQ
                     YEIKVRHGNVFSAAEIGRAYSWALYLWTVIVHPEYDQLVVGSIINWERNAKISDTFES
                     HEYYGHTGVIKGLENGRIQTYEQNAESGGIVAEYDREFFGSGQIASICIPPDFEKGVV
                     INGKVERSTQHN"
     gene            68822..69730
                     /locus_tag="NOB46_000310"
     CDS             68822..69730
                     /locus_tag="NOB46_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HCI1057287.1"
                     /translation="MAKWNVVLSTTEPYNYVGMIQVRQGNKNSEVMEATITENGMPYD
                     LTGCKVYFESVVGDKYPVQLGTKVIDAKKGKIQYTFDQYSMQCLHRQTADFIIYKDDE
                     LIATTQDFSYFVIKAVSKTEGEMGSYWQTVEDLIADMSAFINENKGDFTDWMNARKKE
                     FEQWRQDQQNTFEAWREGQETDYLKWFESIKDILKSIDPGGVMLAELMDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            69730..70518
                     /locus_tag="NOB46_000311"
     CDS             69730..70518
                     /locus_tag="NOB46_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057288.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITSEMYQKILNSGEGDYVLPVATI
                     DRLGGIKIGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGKI
                     NAEVTGFYVLPTASEFVKGGIRVGEGLTMTDDVLSADKQFNYTAGANISISNTGVISA
                     TGGGEGGGVTQEYVDQKMSEAYQNAQAYTDSKIPNVSFEKVGEV"
     gene            70523..70891
                     /locus_tag="NOB46_000312"
     CDS             70523..70891
                     /locus_tag="NOB46_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057289.1"
                     /translation="MTDIVKVKQNDVQVYPQTHWDAVEGKPETIKGDKGDPGQAATIT
                     VGTVTSGTTASVTNAGTASAAKFNFVLPKGDKGDKGDPGANATTTAVATTTANGLMSK
                     EDKVKLDGLANITFEKVGTV"
     gene            70891..71415
                     /locus_tag="NOB46_000313"
     CDS             70891..71415
                     /locus_tag="NOB46_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057290.1"
                     /translation="MADIVQLKEDGVAKYLKTHAKGIDGVEGVLVKATGNETVLGTKN
                     FKDGLQFNGLPVQAGMIERAITLADRSDTTNVTDVNGKIIRIGNIVFLTFNFKCGTWP
                     EGSETRWILKIPDGFKRDQGYPAQTALSLVRNASQPADARAFIDQSSIIQAKSGSGSS
                     YISGMWITQDPWPA"
     gene            71443..71850
                     /locus_tag="NOB46_000314"
     CDS             71443..71850
                     /locus_tag="NOB46_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057291.1"
                     /translation="MKTIYKVLYPMGYEEHQVEDNFPTSLPFVEVPPILFEKKEDETD
                     EGFGRRQQSQFFNFTENKWEEAVTQDYSKKLELLENLSIGLQVDNTALKKSNEELTEK
                     ADSMAQLNAKLMLNDLTINKKIEAIEKQIGGAS"
     gene            71850..71987
                     /locus_tag="NOB46_000315"
     CDS             71850..71987
                     /locus_tag="NOB46_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HCI1057292.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRQFVPLCITDEEADKIISKEESA
                     S"
     gene            72025..72318
                     /locus_tag="NOB46_000316"
     CDS             72025..72318
                     /locus_tag="NOB46_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057293.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIRPIVASFTKITKTLSQVSY
                     NLELLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            72341..>72489
                     /locus_tag="NOB46_000317"
     CDS             72341..>72489
                     /locus_tag="NOB46_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HCI1057294.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVAT"
BASE COUNT        24143 a        11925 c        15280 g        21141 t
ORIGIN      
        1 aaaggcaata cgccttagtt gtcggtcttc gagttaccaa cggtaaccct cataccgaac
       61 ggcattcatc acccacctat agaggatggg cgacttctgc ctaattctgt taaacgtgac
      121 cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc catgcttatt
      181 gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga agaagaaaca
      241 gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat ggtcttattc
      301 ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt tgatggtttg
      361 cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac aacggcaaaa
      421 gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg ttcaaaagcc
      481 tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg cgggctagat
      541 ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa agcttttaga
      601 aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca taaattcatg
      661 catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga actgacaaaa
      721 gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata aattattacg
      781 tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct cgcttctctc
      841 agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt tttatccagg
      901 agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca atcatgatct
      961 gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg gattcaacga
     1021 ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg atcttacgta
     1081 aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt atcttgtggc
     1141 tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg attcctgctc
     1201 tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa ggcatcgtac
     1261 cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat aaatgaaagc
     1321 tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac tcaaaaaacc
     1381 gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga tcaaatttca
     1441 tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg gccattaaca
     1501 agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa tcctctaaat
     1561 gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc taggtctaaa
     1621 ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat ttttaaacaa
     1681 acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc tccagagata
     1741 agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt taagaataaa
     1801 tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc agtcaatgga
     1861 cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc agcaactaag
     1921 tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga aagacccatc
     1981 aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt gatattccat
     2041 gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg aaagacaagg
     2101 caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa acgaaaatca
     2161 gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa actagtactt
     2221 aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc agtaacgata
     2281 gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg aactaaatac
     2341 aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata gaagatcgcg
     2401 ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat gaataagcgt
     2461 gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct caagctggcg
     2521 tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata aatcaggtag
     2581 acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt cttttccatg
     2641 tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg aacttctaca
     2701 tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc tcttgtagac
     2761 ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac tgctttgatc
     2821 aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt catatcaaat
     2881 cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta attcatgttt
     2941 tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa aaaggaaaaa
     3001 aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag taaaatacct
     3061 ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt ttggatgggg
     3121 gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat tttccgatta
     3181 tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc catacgtata
     3241 tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga gaatttaacc
     3301 ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat tcacaattca
     3361 tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat cgaatcaatc
     3421 gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat gtaaaagagt
     3481 attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta ttaaacggaa
     3541 agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt gtgcggacag
     3601 aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa ttttgtggca
     3661 tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat ggtattatca
     3721 ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac aatattatct
     3781 tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga gaaacaaacg
     3841 gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc agctgattga
     3901 acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa ggaacaattt
     3961 caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga gttggtagga
     4021 gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat aagaagagcc
     4081 aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta gatgtaagct
     4141 tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc acagcccttt
     4201 ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc aaaagtcccg
     4261 ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg gcttttgggg
     4321 attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt taatttgata
     4381 ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata acgcgaaaca
     4441 gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat gatgatttct
     4501 actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac acgataatgt
     4561 cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc ttttgcagca
     4621 ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga atcgattctg
     4681 ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc acgctgtccc
     4741 atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct taagtaatta
     4801 tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa gactcgtcct
     4861 ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg atctgttgtg
     4921 aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac cggccagcca
     4981 acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag taacctccga
     5041 tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc aattttttct
     5101 ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg tagtagtaga
     5161 cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt aatacgtaat
     5221 tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt gtatatccat
     5281 ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga atctgtgatt
     5341 tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa tactggcttt
     5401 taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc ttttgttgcg
     5461 tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct gctcttgaaa
     5521 cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg cggataactg
     5581 taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa gggaaataca
     5641 cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca aaccattttt
     5701 tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca aaaggaagta
     5761 ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga ttatggcagt
     5821 agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca cagttgggac
     5881 aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta tctgaaaaac
     5941 cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc tgttcttggg
     6001 ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg ccagccatac
     6061 gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag atattcaggc
     6121 agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg ccgcaattag
     6181 gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat taattaacgg
     6241 ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg ttggaaagat
     6301 ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg ttttctacag
     6361 gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg caaactggac
     6421 atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct gcttgttgtt
     6481 tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt gcattcattc
     6541 ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg gctgcttcca
     6601 taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca cctagcatcg
     6661 ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa atgctggcta
     6721 cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc aatgcagtat
     6781 ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt tgaccatctg
     6841 cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa tactgctcat
     6901 tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta taaaataaaa
     6961 tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat tctgcgttat
     7021 agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc tttatttctt
     7081 ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat ttgaatcggt
     7141 caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga gctgcgtcat
     7201 ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca ccatcgacca
     7261 aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa acatcttctg
     7321 ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct tttgtcatga
     7381 ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct gccagaccgc
     7441 cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc tctgattcag
     7501 ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa acttctcgga
     7561 ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa aagccgagaa
     7621 ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt ttttaaaaaa
     7681 gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag cgtttcgaag
     7741 acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt tcccacaaaa
     7801 cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt gcagcaaaga
     7861 ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc aacgaatgcg
     7921 aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc gatgctgcca
     7981 gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat gcgcctacaa
     8041 aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca ggagctttca
     8101 atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc ttagcaacga
     8161 ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt gattttaaac
     8221 ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa tcgactatca
     8281 gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg atgcgggatg
     8341 cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact ttagatgatg
     8401 ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg agtgcttgcg
     8461 tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca gccggcaaag
     8521 aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg atgtatcagc
     8581 aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt acagaattgg
     8641 cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc gatactcaaa
     8701 atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca gtcaaacttg
     8761 cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat gatcagatag
     8821 taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa ctacgcagta
     8881 atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat aaaaaacaga
     8941 caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa gcgacaagac
     9001 agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta tctgtcactc
     9061 agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga ctagtgattg
     9121 cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg cagctttcgg
     9181 tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt tatattacaa
     9241 gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa gagggaacag
     9301 aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct caagaacaag
     9361 aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc gaagctgtta
     9421 cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat gggcaatatg
     9481 caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc acaagagctg
     9541 ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc ggtttttaca
     9601 ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc tgatgatatc
     9661 gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca aattgatgtg
     9721 gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta gttttaaact
     9781 gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga cagctacatg
     9841 aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac gatcgatatg
     9901 aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg cgatttgcat
     9961 ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg tagaaatcct
    10021 tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat ggcaatggaa
    10081 aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc accgatggaa
    10141 gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca tgatgcagat
    10201 gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac agctatgtat
    10261 ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca tggtctgtct
    10321 gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt cgaaggaaga
    10381 cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag cagcacaaga
    10441 gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga tggtgcagga
    10501 aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa aacagaaatc
    10561 attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc agtgatcctt
    10621 gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc agcagcaaga
    10681 agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat cgttttatgc
    10741 gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat cggcgttacc
    10801 gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt taccctttat
    10861 cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca aaatcaaatc
    10921 gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc ttacttaaag
    10981 ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag ctttgaagaa
    11041 gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt tgaaaactag
    11101 gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac agcaaccgtt
    11161 tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg acaggcggct
    11221 tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt gtagaagaag
    11281 cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct acacctgtta
    11341 cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa gtaggcggtg
    11401 ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag ctgagctatg
    11461 aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct tcaacggagt
    11521 tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg aacaggaaaa
    11581 catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa agacaatctg
    11641 ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc agatgttttg
    11701 gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt gcagacggaa
    11761 ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga agctgaaaaa
    11821 atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc tggagatttt
    11881 ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca atctcgttgt
    11941 caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt gcaagaagag
    12001 cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt aggaaaagca
    12061 gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta tcaatggttc
    12121 gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa attggtaaaa
    12181 tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt ttattatcag
    12241 gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca gataaaccag
    12301 ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag ttttcaggct
    12361 gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga tgatgatcaa
    12421 ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt catatctatt
    12481 attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc gaatctcagc
    12541 aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc aatgaccttc
    12601 ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa aaagacaaaa
    12661 aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg cagttgcgtg
    12721 agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa ttgatttttt
    12781 ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg gccgctgtat
    12841 ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag ataataggcg
    12901 gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat ttcgtgcctg
    12961 tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa atttccggtt
    13021 tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag acagcgaaaa
    13081 aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg aaagtcgtag
    13141 ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa aatcctgtcg
    13201 aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat ggataagaga
    13261 tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt aacagaactt
    13321 gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt ggagatggaa
    13381 aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc tccagctgaa
    13441 aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta tgaagaagga
    13501 ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc ttgtgcgttt
    13561 tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg agactggagc
    13621 ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat aatcaaaaaa
    13681 gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca attggaaatt
    13741 tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt atcgcaagtg
    13801 aggatacgcg taatacacaa aagttattga atcattttga aatccataca ccccaaaaaa
    13861 gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg ttaaaagaag
    13921 gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat cctggacatg
    13981 agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca ggacctacag
    14041 ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta ttttatggct
    14101 tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa gaacagacag
    14161 ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg aatttcttag
    14221 aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc catgaagaat
    14281 accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca gtaaagggtg
    14341 aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa gttgatgaag
    14401 agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa aaaccaaatg
    14461 ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc taccgtcagt
    14521 accatgaatt agactgagat agtataagtt gtctataatg aaagactaat gaggaaatca
    14581 gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat gaataagagg
    14641 tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa atcattcata
    14701 ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag tttcgcggac
    14761 atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta gtgactacag
    14821 caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa aaagcgtatg
    14881 agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc gatatttcca
    14941 aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt agtatcgatg
    15001 aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc aaaatcgccc
    15061 gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg ggagtaagtt
    15121 acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga atcacggtag
    15181 ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa tttcatgggg
    15241 tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga aaagacctat
    15301 atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat tctctttatc
    15361 gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga aaatctgtgg
    15421 gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg actcagttgc
    15481 gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat gggaaaacag
    15541 tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg acattgccag
    15601 aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg gaggaaatct
    15661 tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg gacccgatga
    15721 cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa cagctttgag
    15781 agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag tcttgctttt
    15841 tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca acttgattgg
    15901 attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga aattgtagtt
    15961 ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt tgcgaaagga
    16021 gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct gtccatgacc
    16081 agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc agacaaacat
    16141 ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa tcgttgcgca
    16201 agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat cggaaatttt
    16261 gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg taaagactgt
    16321 tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata tagttttggc
    16381 tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa cttctttcat
    16441 ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata aataagaaca
    16501 aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag ggcgttcaaa
    16561 gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc ttattctgaa
    16621 taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga aaaatatgag
    16681 gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt cacaacctca
    16741 tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca tcggacgagc
    16801 ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt ttggatcatg
    16861 atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac cttcgaaacc
    16921 acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt tgtcatatgc
    16981 aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt attcacagta
    17041 gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca atttttcaaa
    17101 tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt ctttatctgt
    17161 gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt cagttagact
    17221 ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc atgcatctgc
    17281 attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg ggtttgtttc
    17341 ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc ctaacgatac
    17401 agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa gacgtttccc
    17461 gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt tacaacgttc
    17521 tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta actgccagaa
    17581 tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg taacaacacc
    17641 taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc cttgcaagaa
    17701 tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt tatcgtaatt
    17761 cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt tgatgtcgta
    17821 attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca gtttagggaa
    17881 gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa ttgctttttg
    17941 aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga aaggagtttg
    18001 tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag catcgaagat
    18061 atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat cgatccattc
    18121 ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa gcaattcatc
    18181 tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa taatctgtga
    18241 gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat tgccgatttt
    18301 gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca tcggtgtata
    18361 aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat ttgctatatg
    18421 tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca gatctcgctg
    18481 tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt ggtccttgtt
    18541 gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa aatctcgttt
    18601 ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta gtaatatatg
    18661 ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc ttttgatttc
    18721 ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg ataatgagcc
    18781 gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat cgaaatcaac
    18841 atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct gagtaacgac
    18901 agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg ttcttgtcta
    18961 tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt attcaatgtg
    19021 ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa aaaggtgaaa
    19081 acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa ataattgaat
    19141 aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat tattcgtaga
    19201 tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag aattggaaaa
    19261 gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc ccgtcaaagc
    19321 cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta tgggcccaag
    19381 tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc ctacgatggg
    19441 cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc tcagtgactt
    19501 tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata ccctaaatgc
    19561 aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg aaatggaaaa
    19621 gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac ggtatcccga
    19681 tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg ttgttcagcc
    19741 acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg ctacagaatt
    19801 gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt tagtcaccca
    19861 tgatccatat acagcaagct actgcgatag aattttattt attaaagatg gtgtgatttt
    19921 ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa tagacatgca
    19981 ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt aaaagttttt
    20041 ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc gtaatgatct
    20101 attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca agtcaagata
    20161 cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt ttgctttttt
    20221 tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata ggcatctatc
    20281 agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa atcatgataa
    20341 ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc aaactctttt
    20401 caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt atctccattc
    20461 catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta tctgtatatt
    20521 caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa gaacaagcag
    20581 atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc gggttactac
    20641 ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca tggatgatca
    20701 gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt ttcgtttgtg
    20761 tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc atattgagta
    20821 aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg caagttcatt
    20881 tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt tctttaatga
    20941 caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa gtttcctccc
    21001 cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt ctagcagagg
    21061 aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg agtatctata
    21121 gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa acacaatatc
    21181 aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca cctggtcata
    21241 ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat ggatctagta
    21301 ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt gtattaggtg
    21361 acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt tttgaaaaag
    21421 caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat aatgaaaaaa
    21481 tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt tattattctt
    21541 atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt ccggatgacc
    21601 aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct tccagctatt
    21661 cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca ctatttgtcg
    21721 ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta gcagaagcag
    21781 aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa agaaggatca
    21841 gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata ttagggatca
    21901 ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc gattactggt
    21961 tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat gtcattacga
    22021 gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag ataataaata
    22081 gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat ttttgtcaca
    22141 acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa aagcagtgat
    22201 ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa acggtttctg
    22261 taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga ggttatatga
    22321 ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg gggaaaattc
    22381 atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct gtatcactat
    22441 aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga gtatggaaat
    22501 caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc gagttgctta
    22561 tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg cacttgctta
    22621 ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca atttggagtt
    22681 tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt tgccgattga
    22741 agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac catctatggt
    22801 catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa caaaaaaaga
    22861 atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg taaaaggtac
    22921 agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag gcgtacaaat
    22981 cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg ggatcaagcc
    23041 tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat tttctattta
    23101 tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg ttcaagactt
    23161 tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt ctactccatc
    23221 atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc cggaattgga
    23281 catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc tacttgatcg
    23341 attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg tagctatttc
    23401 aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga ttggctacgt
    23461 aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa aaggagaaac
    23521 gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca atcccgaaaa
    23581 gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag gggatgcagg
    23641 tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc aggtcaaatt
    23701 acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag acaaccgaat
    23761 caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc tggttgcttt
    23821 tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat ctatcaaaga
    23881 acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt atgtcgatct
    23941 gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg aggtgaatcc
    24001 tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt tcttttagcc
    24061 attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt accagtttat
    24121 caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta ttggcaacag
    24181 ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg ctattttgtt
    24241 tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt agcgataatt
    24301 ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc gttacttggt
    24361 tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga aataagagat
    24421 ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt ctttccaaca
    24481 atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct ccatccgcct
    24541 gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt tgtcggtttt
    24601 ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt agtgggacgc
    24661 attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta cgtgtacagt
    24721 atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac aagctacatg
    24781 atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa tatcaaagaa
    24841 ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt atatatgcga
    24901 ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat gtcaaatatc
    24961 ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg gtactacatc
    25021 gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat ccgatttaag
    25081 aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc cgtatttttg
    25141 acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga taaacttttt
    25201 tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg aaaatggaag
    25261 aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga aaaaatcgtg
    25321 atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa ttattagtcg
    25381 agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga gaggattgga
    25441 gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta tgaaaaagaa
    25501 actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg tgttttttac
    25561 ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct cttcttccat
    25621 gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg aaaaacaata
    25681 tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc cgtctgttct
    25741 ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg ggacacaatc
    25801 gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca agaaagtcgt
    25861 ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt actttaatac
    25921 gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag taacgcctgc
    25981 tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga atgatacgtt
    26041 gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat ctttgaatca
    26101 gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca atattgggtt
    26161 gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac aataccaaga
    26221 aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga ataatccatt
    26281 cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag agctcaaaca
    26341 gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc agctggtctt
    26401 ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg ttaacgagaa
    26461 atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca aaaagatcaa
    26521 atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc aagcgggtac
    26581 caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg ctgcagatca
    26641 acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc atcttgacga
    26701 tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat taaaataaag
    26761 aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga ataaaagata
    26821 aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca atatgaatat
    26881 agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga tttaacttct
    26941 gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga atatgccaaa
    27001 ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa acatggtgct
    27061 ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt tatggtaaca
    27121 aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg ggggcaagtc
    27181 atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca cggtgtgatt
    27241 ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta tgaaataaag
    27301 gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg gggcatacgt
    27361 cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag taaatattta
    27421 ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt attagagaat
    27481 ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca agaagaagta
    27541 ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc ttttgcttta
    27601 gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga ttcgatttta
    27661 ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa aaaattattg
    27721 aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac agtgatttct
    27781 ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc gtctgtagcc
    27841 attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga agatgattat
    27901 ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga aacagttgaa
    27961 aaaattcgga gttatgaata atgaataata gaatacctat ttctgaatat cggaaaaaag
    28021 cacgagtttc tttggaaaat caatggggaa tcaatacttg gcttgttttc ttatctataa
    28081 tatttacgag cgtcatccag aacttttttg acggtttcag tccttttccg gaagaaagca
    28141 tgcagcagca cttattgagt tttctagtcg ataatttact tttattcgca ttcaactatg
    28201 cattgtttta cattgcgcta gtagttgtac ggggtggcag accaaaaagt aaccttttat
    28261 tttcagtttt ccaaagaaag tattttggtt cgatacttgg catcaatttg atcaattcag
    28321 tcatcaactg gctactcaac agtttaatct ttctgcccat gtttttaatc agcggagtga
    28381 gtacttatat gcagctgctt ttcagttcaa atgcggtacc tacgggtgtc atgccagaag
    28441 attttcttga tatcagcttt gttttatcga tgatagggat gatttttgtt tcagcactca
    28501 tcatgagtat tgttggcggt ttattccaat ttgctgcatg gacaaagttc gactatcctg
    28561 atttgtcggt tattcaatgt ttgaaatatg gctggttttt attgaaagat agaattggta
    28621 cgtatatttt gttgcagctg tcttttatcg gctggtattt gctaggagca atcgctttgt
    28681 tcatcggtct tttgtgggtc attgtttatg tgaatgtgtc agttgcagaa ttttatgaac
    28741 aagcacggat tgaaaaagga ggtccagacg cctattttac ttagcatgta agcagtttat
    28801 tcatcaaaaa aataactttt gtggtaggat aaatctttga gggggaatgt acgatgaaat
    28861 taactgtttt aggatgctta ggagcgtatc cttataaaaa tcaagggaca acaggttatt
    28921 tgcttcaatc tgacgggttc aatttgttga tcgatgcagg tagtgctacg ctgatcaaat
    28981 tacaagaaca ccttgatcca cttgatctag atgctgtgat ccttagccat tatcatcatg
    29041 atcatattgc tgaccttggt gtattacagt attactggca acttcatcct aagagaaatc
    29101 cggagacatt gctttcaatt tatggacaca caaaagattc cattcacttt gaagaattga
    29161 cgttggaaaa tgtctcaaaa ggacatcctt attttgaagc tgaagaatta aaaattggtc
    29221 cttttctgat tacttttatg gaaacaatcc atccagtagt atgttacgcc atgcgtatcg
    29281 tagaagaaac aacggggaaa gtattcgtat ttacaggtga ttcaggttat ttggaaagtt
    29341 tcgctgattt tgcgaaagat gctgatttgt ttctagcaga tacctatctt tttgaaggaa
    29401 atgaacatca tcatgcccat ttcacttcaa aagaagctgg agaacttgcg aaatcagcta
    29461 acgtaaagaa acttgtactt acacacctac ctcagtttgg tgatttagaa caattgaaaa
    29521 atgaagcgca aaaggcagca ggcaaaggga ttgatataga acttgctgca gttgacaaag
    29581 tgtttaacat ttaggaggaa gaacatgatt tttgtaccaa atgaaaacca cgacccaaga
    29641 atcaatttag caattgaaca atatttgctg caagaaatgc ctttagatga acctattttg
    29701 ctcttttata tcaatgaacc ttcaatcatc atcggcagaa accaaaatac gcttgaagaa
    29761 atcaatcgag attatgtgga agaaaatggc attcatgttg tccgtcgctt aagtggaggc
    29821 ggagctgtct accatgattt tggaaacctg aactttagtt ttatcatgcc tgatgatggg
    29881 gattcattcc gtgactttgc gaaagtaaca cagccaatca tccaagcact tcatgaattg
    29941 ggtgttgctg gggcggaatt gaaaggccga aatgatctag tcattgatgg catgaaattt
    30001 tctggcaacg cgatgtatgc taccaacggt cggatgtttg ctcatggaac aattatgttc
    30061 gactctgata tcaatgaagt agtcaatgca ttaaaagtaa aaaaagacaa aatcgaatca
    30121 aaaggaatca aatcgatccg ttctcgtgta acgaatatca aaccatttct tccagaagaa
    30181 aagcaaaaaa tgacaacaga agaatttcgt caagaaatct tgttgaaaat tttcggcgta
    30241 gagtcagtag aagaagtaaa aacgtacgaa ttgactgatg aagattggaa aaaaatcaat
    30301 cgaatctctg aggaatatta tcgaaattgg gattggaatt acgggaagtc tccagatttc
    30361 aatttctctc gccaaaaacg tttttctatc ggttcgattg aagtccattt gaatgtctca
    30421 gaaggaatga tcaaagaagc aaaaatcttt ggcgatttct tcggactagg agatatctct
    30481 gacgtggaaa aaaaattggt tggacagaaa tatgataaag catctctatc aaaaatagtc
    30541 agccaaattg atgtgaagaa atattttggt gcgatagaac cagaagaatt gcttacctta
    30601 ctttattgaa aataaaaaat agcggaatcc acatatatgg attccgctat tttttataca
    30661 ggattcgggt aatttcgaga gagttgaaca gtgatccgat caatgaaagt atctttttcc
    30721 tgcgttagtg ttcctgtgta acgatccgct acgtctttca tcatcattaa gtcaaaacgt
    30781 tcctgatcat ctaattcttc tgtgatgcct cgactaaata ggtttgtatc gtaatgtgca
    30841 ctatgttcgc aacaaatgac gaaatgttcc tcttgttcgt gtatcgacaa ataaattttt
    30901 cgatacagtg gattttcgat ggcatgagtt tctctaaagg aatgctctaa agcgtggatc
    30961 aaaagttgag ccagatcgtc atcgttgata ggaagttctt cgggaagatc tgcttggaag
    31021 gttatctgaa tattccgttt ggcagctaac ttctggtaac gcgctaagat aagatttgtc
    31081 acctggtggt tgcaaaaaga acacagcatt tcgaaatttt ttgcttcttc taatatcttt
    31141 tccacatagt ttttagcttt tgtttggtcc gtatgcatta aatcttgcag attctccatc
    31201 tcttggacaa attccaggcg aagtgtattt acttcttgga tatgctgtcg aagctgctca
    31261 taatgttgct ccaacaaatc atttttgatt tttaagaaat ctacttgtct ccgatctttg
    31321 tcggtattta agatgtgatc gattagattg tagctgataa taacgattag aatgataata
    31381 tataaaatcg tagaccaatt gatcgttgtt tgatagatac ctaatgccgt ttggatgtaa
    31441 atcaagcaat ggataatggc taccaagacg atccaaggtg tacaagctac ataaaaacgg
    31501 ttattcttat atgcttcgcc aatgcatgca agtgaagtga ctaaagtgct tataacacta
    31561 gcaatattag caatcggcat taattcagga agttctgcag gagtaaaagt tgcataaagc
    31621 agaacgccga taaaaatcaa aagttggaac gtacaaaaaa ttccgtacca ttttttatag
    31681 taaaacattc ggctccaata gtagcagatg atgaaagctg acgttaagat aataaataaa
    31741 tgagataaaa aagaatgaac gaatggttca aaaagaatac cacttaaaat atcttctgat
    31801 acagcttcaa atcctaatgc caaagcaaag caacttaaga gaataagtga gtattcaaga
    31861 cgtttttgtt tatacatcaa gtagatcgta tagaaaaagg tccctatagc gataaaaaca
    31921 gcgattatca tcgtcaatac ttgcggcact gattgtgaat aaataaaact aatcaatggt
    31981 ccagttgttc ctagataaac tttcggtggc agtccagcat agttctgata aggagatgag
    32041 actgtaaggg tcaatttttt tccgatataa tttgctggta aatctatcac agccaatgag
    32101 agtccgggat tgctttcttc ctgataatct ttccgttggt ataaaatctt ttcgcctaga
    32161 tatacagtaa tccattgatg gtttcctttg attagtaaat ttgcttcgtc caacggtttt
    32221 tcaagtgtcg tttccataat gaatgtttcg tctttatcca cggtaggaat cgtacgagtg
    32281 tacttgctgt caaacttaaa atcaggatca tcttttgtat agaaaaccca cgaatctttt
    32341 atttctttca tttgattgct gtccgcagga gaaaaaataa aataaaagaa ataagcaatt
    32401 cctgttaaaa ataacaatga taatataatg attatgctcc actttatacg taaataaaaa
    32461 gattcttttt tattatatat gttattaaaa aaagacataa aggtattcct ttctaaaact
    32521 tgtaatgtta gggtaaacgt tttttaaact aacgtcaatt atttataata aaaaatgaga
    32581 taaagatgag gaaatagaat tagaaacata taattattaa agggaaacat ttttacagct
    32641 ataatttgaa aaaaatttat cgttattata tgattaagaa ggattgaata aagaaagaag
    32701 ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac gttgattata
    32761 tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt gactccttat
    32821 attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat atatgtacga
    32881 ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga aaattcagga
    32941 aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga tttttataca
    33001 aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa tattatcggt
    33061 agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc atttgcatgg
    33121 attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc atggaatacc
    33181 tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga atgttaaaaa
    33241 cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag aaaacactca
    33301 tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga gtagtatgcg
    33361 caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta tgcgtaccca
    33421 gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg tagcagaagt
    33481 accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac agcttcagcc
    33541 tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca tggccacgac
    33601 aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga tcgagaaagc
    33661 taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg aaggtcaagc
    33721 agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg atagtgcaaa
    33781 atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag gtggcgtttt
    33841 gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag agattccccg
    33901 tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga tggatcatcc
    33961 cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga caaaggaatc
    34021 agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga ttgaatcgag
    34081 ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa aggatacagg
    34141 aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca attgataacc
    34201 ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt tgggccaaaa
    34261 taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat ttaattatct
    34321 ataattattg atgttccgct gattcttgtc atagtagctc agctggatag agcatccgcc
    34381 ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac cgttagaaac
    34441 tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt tcaaaggcaa
    34501 ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa taaaactcat
    34561 cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc tagttgcaat
    34621 tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca cgacaagtag
    34681 ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat tgtttaagaa
    34741 ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt atctttcttc
    34801 cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg cattatatgg
    34861 cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc tgttggcatt
    34921 gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg aaactttgtg
    34981 aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt tagaaaattt
    35041 catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa aaaagaattt
    35101 tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac agtagctgct
    35161 gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc ggccgcaggt
    35221 ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg tttttatcaa
    35281 atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc aacaaaggga
    35341 atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc agcaggactt
    35401 ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg gtttacttca
    35461 ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt tcactcggaa
    35521 ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc gataaacaca
    35581 gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc aaaaaaatgg
    35641 gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt tatgctattg
    35701 ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag tagtaatcgt
    35761 ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc agctattagc
    35821 attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg ccgaatggca
    35881 aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa tctgttgctt
    35941 cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt ggccatcaaa
    36001 tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact gctctccatg
    36061 cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg tgttttgatt
    36121 gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac taataaatat
    36181 tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt tgatttaagt
    36241 attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa aagcgctgct
    36301 atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga aacggaaaag
    36361 ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc ttcagaaaaa
    36421 ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc catgcgaggc
    36481 gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga aaaagcagag
    36541 caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa acaactttct
    36601 cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc gttgacagct
    36661 ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca gacaagactg
    36721 taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa agtgaagcta
    36781 gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa atagctgctg
    36841 gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca tccttttgtt
    36901 ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta accgtatatt
    36961 ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat tttggctgga
    37021 ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa cgagtaggtg
    37081 tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga tgagtcacgc
    37141 gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt aagccagttg
    37201 aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca tgcgtatcaa
    37261 tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga ggtccttgcc
    37321 cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct tgtatcagtt
    37381 cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata aaagaaacac
    37441 aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta ttgcttgaat
    37501 ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc tggtaagcta
    37561 gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa taagcacagc
    37621 atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct ttatagcatg
    37681 tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca agcaatctat
    37741 gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt tatcttagta
    37801 ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt tgaaggtact
    37861 gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc taaaaaacat
    37921 tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga cgcgatcaac
    37981 gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt aagcgaaatg
    38041 acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt ccttatggaa
    38101 gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac gggattgcct
    38161 cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt tatctttata
    38221 ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt ctattagaaa
    38281 atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc caaattaaaa
    38341 caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta caattatttg
    38401 cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca aaacgtctag
    38461 gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac cgtcaacgcg
    38521 gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact ttatttgcaa
    38581 aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa gtgtctgttt
    38641 atccagtagc tcaagaagct taataaataa actgctctat ctcttgtgtg gcaagggatg
    38701 gagctttttt tgctaagtaa gggatttttt tgaccatact tttgaccata ctttcttaga
    38761 agttaatata atttgttagt ttttgtgttg tttcttcttt tttgctgtta gtaatgtgtg
    38821 tatatgtgtc catagtagtt tttatatttg cgtggcccat tctttcttgg acttctttgt
    38881 gatctgcgcc tgcctcatat agcattgatg catgtgtatg tctaaaacca tgcagaccga
    38941 tataaggtaa gccggcacgc tcacgatata tattgtatct ttctgccact gactgattaa
    39001 ttgtgaaatt attttcgtca ttggtaaaca aataattagc tttagtaaat cctaattgaa
    39061 ataagtactt tctttgttcg agcttccaaa attttagttg ctttatagtt ttttcatcta
    39121 aataaattat tcgatttgat ttttttgttt taggagtttc agatatataa tatttatctg
    39181 aacgagctac agttttttta atggccattt catttgtttt aaaattaata ttgtcccaag
    39241 tgagtgctaa tatttcgccg attctacatc cgctgaatgc taatagtcta aagagcgtat
    39301 agtctctgtt tttaaaatat ggattctgtt cttgagatac ttcatttaga aataattcca
    39361 actgttcttt tgtatataat tttaatttct tttctgtttt aatttgtggc tttggaataa
    39421 gtaaatttaa tgttggatta tcagatgtta aaccaatatt tatagcatac ttaaaaactt
    39481 tgttcatata gtttatgaaa agagggtact gctttgaagt tcctttttca ctccaatcat
    39541 ttactacctt ttgacaatat gccgtattaa ttttagaaag cttaatattt ccaaatttgg
    39601 gatatatatg tttattaaag attattttag tccttgaata tgaactttct tttacagttt
    39661 ttttgtagct ttctagccat aattctgctg cttctttgaa agtagtattt gtacttgtgg
    39721 gcattcctgt tttttgtaat tctagttcta acctagaaag tgctgttttt gcttcttttt
    39781 gtgttctaaa tcctcgttta gtagtatatt ttttctttcc tgttagcgga tcaataccga
    39841 gataagtttt aaagtaccat gctttttcgc catttttctt tttatattgt tttatcattg
    39901 ccatcaatat tacccctatt caaattctaa ttctgccatg ctatcattga aaaattcgat
    39961 cagtccttgt tcctctataa attcaagcca tatttccttc ccgttaatta atggaactcc
    40021 tttttcttta cgaattgttt gatacaagtt agtcacgact tgtttccaca tttctaatac
    40081 agctttatct attttcttat catcccagcg tttttttggg ggtctatttt tatttttttc
    40141 aatttgataa ttagtagctt tgatgataaa tgtttcgtat ccgattgtgt ttttttctaa
    40201 ccattctttg aattctggat atatcatttt agttcacctt tcttttttga acatatgttc
    40261 tttttttgtt taaaaaaata ttagagagct acataacaat aaatgcgagc ttttaataat
    40321 tctttcacaa gcggttcgaa gcgaacactt aaattattat cttcgataaa tttcatgtaa
    40381 ttgatgttgt gtggttccaa ttcagatttt gcaatatagc tatctaataa attttcaatc
    40441 ataaagcgat cagcttcata ttccattttt gaatgtagag agaatgctaa gttatataaa
    40501 aaataattat catgatgttt agaagcgtgt cccaattcat gtaataaggt tctttgtctt
    40561 ctatacttag ataaattagc ttttattact atggtattca tacatgcgat ataatgacca
    40621 tctgcgtcaa gatgttcttt ttcttccacc ttaacgccga gttcattaat tatcatttca
    40681 atttgattgt ccaactgact cacctactta tttagttatc ttttttctct aaatatgctt
    40741 caatcatagc tgatagtatt tccctatcat tatcggtgag cggttttccg tcgctactca
    40801 taacagatgc taaagcttct tccacagtta gttttctttc ctctggtgca actcctatgt
    40861 cgggatcatc tgtgcgtcct aacaaataat cagttgagac attaaaatag tcagcaactg
    40921 catttagttt atcaatggat ggcttacttt ttttccacgc gtaaagtgaa tttttactaa
    40981 aattaagttt ttcttccaat tcgacaatag atattttgcg tttatctgct aacattttta
    41041 ctctctcaaa tgttgtcata ataatgattc tccgatcatg cctaaaacac atcttaaaaa
    41101 ctttgtagat aatcgttgac atctacaaaa ctttataata atatatgttc gtaagctaat
    41161 ttaataagct aacaagcaat aagaaagaca cctaataaag taaacaaatt cgaggtcggg
    41221 aaacttagaa tgttaattta tagggtaatt ctgcgcttat ttaactatgc acttattcta
    41281 caaaactttg tagaaagtgt caacaaaatt agctaatttt attagcttac agaatttaac
    41341 aagggagaga tacacatatg acaaacttag taattatgaa agatcaacaa gcagtaacga
    41401 ctagtttgca agtagcggag gtgttcggga aagaacataa agttgttcta aaagccatcg
    41461 atgagctgaa agaaggggtg gcacaaaatt atgcagacct attttacgaa gatacttata
    41521 ttcatcccca aaacaaacaa aaatatcgtc aaataattat gaatcgtgat ggatttacat
    41581 tgcttgctat gggatttact ggaaagaaag cattgcaatt taaattgcag tatataaacg
    41641 cattcaatga aatggaaaaa acaataaaag agaaatcagt atccattcca actacaaaaa
    41701 gaggattggc actactagct ttagaagcaa gtgaggaaac taatcaacga gtggatgtca
    41761 ttgaacaaga agttttcgat ttaaaagaaa atcagccgtt accacaaggt gaatacagca
    41821 ttatttcttc tcgaattaat aaaagagtgt acgaagtagc ggatgcctac tcaattaatc
    41881 gctcaaatcg taaaactatt ggattacttt tcaaagatat aaacagtgga gtcaaaaaga
    41941 tttcaggtgt aggagcacgg actcaactga gagccaaaca ctacgaaaag gtgatggact
    42001 ttattaatag ttgggaacca tctagtgtaa cgaaattcga attaagacaa acaagaatgg
    42061 atgtttagga ggagttagtt atgtcgcagg acttcatttt aaaagtacgt gtggcgttag
    42121 ctacgcatga caagagtcaa gcttggttag ctgaacagct tgatatttca acagcttaca
    42181 tgtcggatat tatgaatgga cgtagaaagc cagataaaca aatcaagcca attgaggcag
    42241 tgctagcaga attagaaaag gagaaaaatt atgcaaataa caattccaga taatttagta
    42301 gtttcagaat taactacaca gattacgaat gctgtgctta attcgttgga cgaacgattg
    42361 cgccttatga acaaatcagt ggagcttcct ccatatccaa acaaatcaga ggtaaaaaaa
    42421 gttttaggca ttggtgatga caaattaaca cattggataa acctaggctt aaaaacacag
    42481 cagtggagta agttagacat cagaattgaa cgatcggagc tccaaagatt tttgaaagaa
    42541 aactttgagt tctaaaggca aaggagaatg agtttatgtc ctacacattg caacaagaac
    42601 atcaaactct ccgtttgatt aaacaacgca ggaaacaatt acaagatgat cgtgaagcgc
    42661 ttagaaaagc cgatgagcta ccagatagac aagctgaact aatcgcttct gaacttgagg
    42721 atttgagaat gctagaaata aaaaataggg agattagatt atgaagaaga cagacacact
    42781 ttttatagga ttcatcctag ggctattagt gatagtagca caccaaagta ttatcggggg
    42841 aagtttgttc gcagcattga tggttttaat caatctgctt gattcaaaag aaaggagcaa
    42901 ctatggcacg agaagaagcg ctaaaaatcg gtaaagtgat tgctgataat tggtgggcaa
    42961 atagccgttc tattatttta agcaagcaac atatcgaaaa gaaaaaagca tggcaacaaa
    43021 taaaaaagtg actccgccga ccaaagcaat gagtcactca aaaaatcata actaaggaga
    43081 ttttaacata tggaaaatga actttccact ctagatcaat atttggccga tcctgattgg
    43141 ggcaaatcga atagtaagga aacaaacaac cgaaaaatca gacgaaatct tttgacaaat
    43201 gaagaactag catgtgatca agatgacttg ggaaactttg tgagtatttg ggatcatgtt
    43261 taccttatcc atctatcgaa acattcgaat aaacctgaat atatttatgt cgccgaagat
    43321 ggcttgattg atgcgctcga agagtacgaa agggataact tgattgatat ctcttattac
    43381 ggacaaggca aaaaatacat cgctgaaatg gaggcagaat ttgatgagtg aaaaggaaca
    43441 acctttgaaa aatagaagtg ataatacgct ttttaatagc ttatacaaaa taaatgtgaa
    43501 aggtgttact gaaaaacgaa ataacctcac ttatctttcg tgggcatggg cttgggcaga
    43561 agttagcaaa gtgtgtgagg cagtagatta tgaaatctat cgtgatccag aaacgcatcg
    43621 tccatacctc tttgatgaaa aaacaggcta tatggttttt accagtatca cagtcaacgg
    43681 agtaaagcgt gacatgtggt taccagtcat ggatggtgca aacaaggcaa tgaaagatga
    43741 gccatatacc tacgaagtca atgattatca gtggaataac gaaacgaaga aaaaagagat
    43801 tgttggaaaa atcgaaaagc gagttgaagc agcaactatg tttgatatca acaaaacgat
    43861 catgcgctgt cttgtaaaaa atctagcaat gtttgggcta gggctatata tatttgctgg
    43921 tgaagatatg ccagaagacg tctcgatgct tgaaccagct actcaaagaa gcaaaaagct
    43981 attcttggat gctttacaac tggttgctaa caagtacgaa aaatcaattg atgaagcaat
    44041 tgttgcattg actgatgcgg cttctataac cgctgatgac agtaaatgga ccaagagaga
    44101 cttgggcatt ctaaaacgag gcgttaactg gcttgaagat cagtacagag aagaaacaaa
    44161 agagaagtga tatgaatgtt taaaccgtta atagactcat actcggcggt actaagaaga
    44221 ttcaaaggca accagatagt ggcaagaatc aatgaagaag tgaatatcga gcgattgaag
    44281 acgatgtatg acggctacga tggcgatcga gtcattgaaa ttcgctttat tgatccacgt
    44341 cggttcacag tacagcaaag aaacttcatc tatgcgctca taggcgatat tttcatcgat
    44401 acaggaatgc caacggactt ctggaaggaa ttcttctact tccgttttga aggtgtcaca
    44461 ggacgttcta taagccttaa agacgagtca agctcaacag tgagcgatgc aaatgtctta
    44521 gcaaatatca tcttagattt tatttttgaa caccatatcc cctttaaaga aggctatgag
    44581 attttaccag gcaaccaaga gtattacttt tacaaatgca tcacaaaaag agtctgctgt
    44641 atctgtggca aaacaggagc tgatatcgat cactttgata aagcgttagg aagacgaaag
    44701 cgcaaagaag ttgatcatgc agagtacaca tttgcagcac tctgcagaat ccatcacaca
    44761 gagaaacaca aaataggtgt gatcaatttc aaaaataaat atcaaatcaa agggatcaag
    44821 ttaaaccagg agacaatcaa aaagttaaat atcggaggat aaggaaaagg tggtattgaa
    44881 gtgtcagaca aacaaaagaa acgctattac tggcttaaat taaaagaaga ttttttcgaa
    44941 gaagatacca tcgaatggtt ggaagaacaa ccgaatggta aagaatattg tttattttat
    45001 ctgaaactct gtcttaaatc tctaaagaca gaaggaatac tagttagaaa tgtaggtaat
    45061 ctgatgatac cttacgatcc cgaatctcta gcaaaactaa caaattcaaa tacggacaca
    45121 gtgaaagtcg ctatggatct attcaacaaa atcggactaa taaaaatact ggacagcgga
    45181 gagatatatc taaatcagct aagtgaatta gtaggatcag agactgaata cgctaggcaa
    45241 aaacgaatcc aaagagcaaa ggaggacaat gtccagaagt tgtctggaaa aggtcgccta
    45301 gagatagagt tagagaaaga tatagatata gatatagata aagaagaaaa gaaaggtaag
    45361 tattctgacg aacacttacg ccttgctaaa aaattgcaaa gtaatttaac tgaagatttt
    45421 ccaaaagaaa tgaataaagt agatatcgaa aaatgggcag acacaatcag gttgatggaa
    45481 gaaagagata aagcatctat agaagcgatt gagtatgtga tcaattggct acctacaaat
    45541 gaattttggt ttggaaatat tagaagtgct aagaaattga gagaaaaatt tgagaagctc
    45601 aaattcgaaa tcaaagcaga taagaataat cataaaaagc aaagtcaaaa actacagtac
    45661 agcaatccta gtgaatatga cgacttgcca atttaaaaag gagatgcatc acatggaaag
    45721 cctagcaaat gctatggaga aactaataag aagagtatta gtgcaaagcg gaaaatgtcc
    45781 agaatgtagc gaacctttgt atagttggcg agctaaaaat aaggatggtt cagaacgttg
    45841 taaaccaaca tgcatgagtt gtggttataa agcgttacgt gtgaaagagg atatacagac
    45901 cgaacggata tataacgaca gcttaaaagc acgagcgttg agtttttttc aaaatggttc
    45961 ggtattaaca gataaaactt tgtttaaatg caaaatggag aattatcatg tagtggacca
    46021 agaaacgaaa attgctttag aaagagctaa aagctatgta aatgatgtcc tactgaatca
    46081 tcctgcacat ttcattctat cagggaaatc aggaagcgga aaaagccact tgtcaatggc
    46141 gatagcttgg gaaatacttg agcgctcaaa ttatgacaag aaaatacttt ttataagcta
    46201 tcaagagtta ttagagcaaa taaagttttc ttataacaat gctgaactga gaaaagaaat
    46261 tgaaggatcg cttatagccg atattaaaac aactgatttg gtggtttttg acgatattgg
    46321 agctgaatta ggtagcgggg tatcaaatag taggcagttt acaaacaaca cgttaaacac
    46381 gctcttagaa gccagacaga acaaggcaac gatcatcaca acaaacttat ctggtcctga
    46441 actaagagaa gcctacggtg aaagaattgt ttctaggata tttaagaatt cagaaggtta
    46501 tgcgctgaaa ttccaacaaa cagcagacaa gcgcataaaa ccagtgaaag gtagtatcgc
    46561 atgaataaat accgtaataa aaaaactgtt catcgaggta tcaagtttga ttctatcgcg
    46621 gaagcagagt attacgatct agccttgtgg caagcacagg cgaatggttg gaaagtgaag
    46681 ctccaggaaa ggtttgagct gatgccgaag tttgaactag agggcaagaa gtatcgcaag
    46741 atcgagtata ttcccgactt cacattttat aaaaacggca aacttgtcaa agtagtagat
    46801 gttaaaggaa tgcagacaaa agactttaag atcaaggcaa agttgttctg tcatcaatat
    46861 caagtgccgt tgatattagc caaaaaatat cggaatacgt tcaaggaaga gcgtttttaa
    46921 agaggtggtc tatcatgaca acagaagaag tgattcaaat gcgtattcga aacattcagc
    46981 gtgaaattga cgatctggaa cgaacaaagg cagtgatggt caatgaaacg gcgagaaagg
    47041 caatcgattt gcacatagag aatttaagaa gggaaattcg tagattggag gaatgatcgt
    47101 ggataagaaa gcagcaatga aaagaattgc tgaattaacc aagtcagaat cttggcaaga
    47161 agacaaagaa atagttgcag aagtccaaaa gcttggtaaa ccaatgtggg ctgaaaaaac
    47221 caaacggaga acgccgagaa gaattgcaat ctggcatggt gaccgaattc tagtaacagg
    47281 taccgctgaa cagttatctg aaattactgg attaagcaaa aacatcatct gggatagggc
    47341 taggagctta tggattgatt caaaaggacg acagtttagg tatgtggagg agaaaaaatg
    47401 ctagatatga aaatcgaaga ttatcgaatt accagtgatt ctagaaatat tgtcttatcg
    47461 aaggtaagac gagatgagga aggaaacatt cgctacaccg aagcaaaaga agaatcacga
    47521 gcagatattg gatacttcca aactgtctca tcgtgtttaa aggcgataca acgcgattac
    47581 gtgttaagtg aagaaagaac gataaaaagt attatcgagt acaaaaaagc gttagaaaac
    47641 atcactagac agtttgaaca ggcatgtgag attgaggagg agaaataatg gatctcatta
    47701 cacaatacag tgacatcatc ctcaagaaaa tcatgatgaa gattcagaaa gataaaaaat
    47761 caaaagaacg agctgaatta gttaagttag aaatggctga aacaggagca ggagtgcgaa
    47821 gtagcaggca ttggaaagca gcagcaaaca ttgaatttta ttacaacgaa attcaaaaag
    47881 ggttcgatca gatgcgtgag ctggatcggc aaacaaattg gagcaagaaa cttcatcaag
    47941 atcgtttcaa atttgtagaa aagtatagag agatattaga cgaatacatg gaggacagca
    48001 aatgatcagc ctaacaatat tttggtgtgt aattggcggc ttactagcga tgttaggagc
    48061 atacctcatt tacgagagtg caaaaggcaa aaaatataca gcattaggga ttattttgtt
    48121 tgttgtcgga attttagttg cgattggtgc agaaataaat ctttatttaa acggtacgac
    48181 agaagagttg atgtggtttt tattgtggac aaggagatag gaggacagca aatgataccg
    48241 agatacagag tgtgggataa gcaaacagaa aggatgcata ttgttagcgg aatagatttc
    48301 aatgatggtt tagtatccag cgttaacata tggcatgaag ggtggccttg ggtattggaa
    48361 cccgatgaaa ttgtgcttat gcaatcaaca ggactgaaag ataagaatgg tgtggagata
    48421 tttgaagggg atgtagtatt agtcagcgtg cgaaatggct tcgattactt agataataaa
    48481 gtttgtattg tcaaaaattc aatagattat tccggattag tttgtgccac tgttgatgaa
    48541 gatttagagt atcgaatttt taacacagag ctgtttgaag aatacacgta tgaagtcatc
    48601 ggaaatatat acgagaatag cgagttattg gaggaacagc gatgaataaa caagaattga
    48661 ttgataaact agcaagcctt gtaggtagca tagaggactt taaaggtata agtacttttc
    48721 atgatggaaa atatgcgggt ttagaacacg cattagaact aatccaacaa ctagacgaac
    48781 tgcagaatcc agttgaatca aaaattacag acgaacaagc ttggaataag gtagctgagg
    48841 cttatcctga atcggcacaa agcttgagaa acactttaga taatgctgta tttggtaaga
    48901 ctggtgaacc gcagaaacac gttatgccga agttttttga caaatgggca aaacaagtcc
    48961 tggaaaaacg tgacaagttt tatgctatct ctcttattac acgcgcgggc tgggggtatg
    49021 gtgttgatta tgaactcgat aatggcagat cgccatcagg aacaaaagag ctgttgaact
    49081 ggattgttga gaatgaaggt gatgattatc ctaataaaaa gaaagcaaca gaagctttgt
    49141 tatacggata cgaggtcgag gaagagccat tgtattatgt gaagttacca gttgtgtatt
    49201 ttaatcattt ggatttagag acgtatctaa tgaaagatga tcgaggaaat ataacaattg
    49261 cagacaacaa tgattttgat gatatgaaat ttacggaatc agaaataaaa gcaattgatg
    49321 aaagatactg gccatttgct gtgccagtcg agaaagtgta ggttcaatcg gatgatcaaa
    49381 aaaataaaaa ctttgatcga tggttttctg ctagaaagaa aactcgttaa ggttagagaa
    49441 ttaataaaga ttcatataga tagcggtgaa cgttcaatgt attgggtcgc cactgatagc
    49501 gaaaagcaga atgttatgaa catgatcaga ttttttgaga ttgcattcga agatggatat
    49561 tttgcgactg gtgagtattt tgatgcttct tcatggatgt cttcgaatcc agaagaagtg
    49621 tggcaaattt atttggaaat gaaagaggtg gcggaaggat gagcagacat ctaatgctcc
    49681 atataccaga cggaacaaag gcaattgcaa ttagtattgt tgctgaacga aaagatggtg
    49741 gtttggcatt gaccacaaaa ggtattgata ccaaacagat tttagaaggc agagatgtcg
    49801 agatagagat caatgaggag gaagcggaat gaaactaaaa gacggattct acgctagtag
    49861 tcatggtatc ggcggtttaa tgctagatat gccgacaaag aatcctaaaa cacgtaagaa
    49921 accaaaattc aaagtcggtg acatggttcg ctgcgaagca gaaggattca gctatccatt
    49981 tcgtggatat gtagagcatc tctataatca ctcagcaatc attcgtattg aaaacacgat
    50041 gaaatgtgat aagtggttag cgaaaagcaa agagaattta gctgtagcga gattggtgga
    50101 tattgaacta atcaatgaca aataaaaaag ccggatcgct ccgactgatg taataaatcc
    50161 gacaagttta ttatatcaca taaaaggagc ggtttgactt gatgcaattg ttacgagagg
    50221 tagatttcaa acagacaaga tgtaatgcga gagacgtgct gaagaacttt cggcgtttgg
    50281 agcggatggc aggtcgctct ttgatagata ttaagtcgcc gattattacg gatatgccga
    50341 aggcaccgaa gcacggcaat aaggcagagg acgcgatcat acagatgatg gatatagaag
    50401 cagagagaga tgcgatttta gcggctttga tggcacttag tctgattagt cgtcagatac
    50461 tctactacag cttctgtgac gtaaacaagc actctaatta tgaaataggg caattgatac
    50521 gaggatacgg agagaaaaat gtagagaagc tgaaatccat cgcattgata gaatttgcag
    50581 aagcatacaa aaaaggcgtg ttagttcagt atcgttgatt ttgtagggtt tttgtaggga
    50641 tagtgtaggg tttttgagcg gtttaacgtg atattatggt agtgtcgaaa gattaggaaa
    50701 caggacttcg acaaaataaa atgtaaggga ggaaatctcc ctcatcgttt taattaagct
    50761 tcgatagaca gcagcggaaa tattaagaat aaggatgtga atttcaactc cttctaaatt
    50821 gttcttatta tctatcatcc gttgctgtct attaatttat gtattggagg aaaaacgaat
    50881 ggataaagaa atcaaagcaa atttcaaatt agatttgact gaactaaaag aactactcaa
    50941 caaggctagt gaccaagtcg aacaaataaa gtatcaaggt atggatcggg aacggttgat
    51001 tgatattatt gagcaacaac gtttagaatt gatccaaaaa gaagctgtat gtaaagagta
    51061 caaaaaacat ttagaacaag taattgagta tcattcagta gaaaagtaca gatcagtggt
    51121 gcaaaaaaat agagcaacga ttcctgatcc tcgtcaagat gtatcgatta gtatcaagac
    51181 gccagtattt aattctgtta aatcagaaaa gctagaaagt atctcaactg ctttggtaga
    51241 aaaagcagct gaaatgaact ccctagcaaa tgaagttagt cgtcttattt agtcacattg
    51301 ataacttgag agtctttggt gattccgttt tttatagaat taatggtttg ttcagcggac
    51361 cactcgctga taattaaaat tatacgctta gtatttattt tcacaatatt aatttgtcac
    51421 tgtggcggaa aggtaacgct aataacttaa atcagtggta atgaacacct gagcttagtt
    51481 tatgcagcta ggcaagagac cgtcgagggt aatgggcaag aggcatcttg aataattccc
    51541 ctaaagatag acaattctag aggtgagagc ttttatgatg gagagtctgt aaaatatcgg
    51601 aaaatggtgt tgcaatgttc gattcattgt cagtgactta aggaacctac ggaaacaatt
    51661 catcttatcg gatgccgatg aattggctga ctagtcggga tgccactagc agttaaaagg
    51721 cataaaatac tagcgcagac gtgcgccact ctcaggtgta ggttaggaga gaaacattag
    51781 ttggggttat taggaatacg ataacctgct tgcgacaaag ctttgtactg tcgcgttggt
    51841 catgaacaga gacggtattc tgtttcagta ttcgttagca accgagggtt ggaaacgggc
    51901 gctcaaagta cacgagcaag gcgaggtcga tagtaatcga tggaatcggt gtaggttgct
    51961 attacataat tggttaggtt agattgagtt ttgggattcg gtacaaatga atcgtcaaat
    52021 gactcaagca caggatcgga aacgtccctg cctgtgcatt acatattaga tcactctttg
    52081 agtggtcttt ttattttaga aaagagagga ttttgaaaat gaatcatgag aagtttatcg
    52141 aaaaatgcaa ggctattgta cgtgaaaaaa ttgaaaatga gattgctgac ctaagtggag
    52201 cagtgcctga gtttagtgtt tttatagtct ggtcatgcaa aacactgcaa aatagcaaag
    52261 cattagtcag cgctagctta aaaggagcac cgtattttga aattacgttg aacggggaca
    52321 aaggtgaaat ctatgtagat acttatctca aaaaatcaaa tgaatgtatc aaagtctagc
    52381 aggtgctagg ctttttcttt acataaggga ggctgcataa tgagaaacta ctggtatgta
    52441 tcgctaacta atgaatatcc tcgaaccatt gatgattgtt cagtgcgtgt tgtgcgttct
    52501 gtacaaatca aagggaagta ctctattgtt gaaatgggga gagaagcaac accaaaagag
    52561 attgataaat gcaaacttct ttattgcggt catggatatt ggaaagacga atatattcag
    52621 aaaaatatta ggaggtactt atcataaaaa atttttatga agctgttcta aaaacaacag
    52681 taagcaaaga gttatcaaaa gtgtataaga aagcattgga aattgaaaac gatcgtaaat
    52741 gggtagaaaa ctctattact gctaatggag aaaccaccat tgaaattaaa ccggtttggg
    52801 gcggttgtta tgcgaacgta gatatcacag aaatcggaga aggtaaagct gtgttgattc
    52861 taactctagt atcaagaact ttacctaatt tgaaagaaac agttagaagt tatgaactag
    52921 acggaatgga aactatccat accagttatt aattacacat attgaaaggt ggtgatggaa
    52981 aatgagtaag ttgaatccta agcaacaagc ctttgctgat gagtacatca tcacaggcaa
    53041 tgcttatcag tcagcactga aagctggcta taaagaaaac tacgctaaga acgcacaaga
    53101 aaaattggtg gaaaaaggtg gaaaagtatc cgactacatt caagagaagc taaaagaagt
    53161 tcaaactaag aggcatttaa caatggaaga agctttggct attactgctt ctattgcaaa
    53221 aggagaacca caacgctttg aagttgttaa gagagatcct tatacaaacg aaatcataga
    53281 acgtgaagtg agtgaatatt cagcaggttt caaagaacgt aaccaagcac ttgagcatta
    53341 ttataaaata aacgcagcat ttgtagataa gcagaaagtt gaaatttctg aaatacctac
    53401 tttcattgat gatataagta gtgatgatga tggctaaaaa actatctgaa tttcttccgc
    53461 cgaagtttca ttcagtatgg agagcgactt taaatcaaga cattcttaat atagtttgta
    53521 aaggtggccg gggttcagga aaatcttcag atatagcgca tatcgttact cagttactta
    53581 tgagatatgc agtgaatgct gtaggtatac gttatgttga taatacactt gagcaatcta
    53641 tttacgaaca aatgaaatgg gcaattgaga agcagggagt atcgcgccta tttaagttta
    53701 ataagtcacc acttaaaatt acttatcttc caagagggaa ttatatgata tttcgtggtg
    53761 ctcaaaaccc agaacgaatc aagtctttaa aagatagcaa gtttccattt gctataggtt
    53821 ggattgaaga attagcagaa tttaaaacag aagatgaagt cacgactatc acgaactccc
    53881 ttttacgtgg agaattagat gatggtcttt tttataagtt tttttacagc tacaatccac
    53941 ctaagagaaa acaatcttgg gtaaataaaa aatatgagac ttcttttcaa ccagacaaca
    54001 cttttattca tcactcgacc tatcgggata atccattcat ctctaaggaa tttctgaaag
    54061 aagttgaggc aactagagca aggaatccaa gaagggctga gtgggaatat gatggtaaag
    54121 ctgtggggtc aggagttgta ccttttgata atctacaagt taagaaaggt tctattacag
    54181 atgaaatgat ctctaacttt gataacatcc gcaacggttt ggactatgga tatgcaacgg
    54241 atcctttagc gttcgtcaga tggcattatg acaaaaagaa aaacggtatt tatgcaatcg
    54301 atgaaattta cggcgtgaag atcagcaata gagaatttgc aaacaaagct aaatctaaag
    54361 gttaccaaaa tgaggagata ttttcagata gcgcagagcc aaagagtaat gctgaattag
    54421 ttaatgaaca tggcatgaaa ggaataaaag gcgtgaaaaa aggacctgat tctgttgagt
    54481 acggtgaaca gtggctagat gatttggctt ttatttgtat tgatccacta cgcactccga
    54541 atattgctaa ggaattcgag aacatcgact atcaaacaga tcgtgatgga aatcctaagc
    54601 caaggttaga ggataaagat aaccatacga ttgatgcgac aagatacgcc ttcaacgaag
    54661 acatgtgggc caaaaagaaa tcaaccgtta ctaaagagca gcggaacaaa atcagaagaa
    54721 tgttttaagg agtgtgagaa atggataagg taaacgaatt tgaatacggt gctgatatac
    54781 attattcgaa cgacgtgaac acaaattatg taaagtttag cgtagattcc aatcttcact
    54841 ataggtttag ctcagcagaa gatttactta acgatttaga tactttagca gcaatgataa
    54901 aacatcatca tgaatatcag gtaaaaaggc taagtgtatt agatgattat tacaaagcta
    54961 gaaatacaaa tatcatggat aaccgtagac gtagagaaaa ggaaaaagcg gatcatcgat
    55021 cagcacataa ctttggaaaa gttctttgta cgtttgatgt tgggtacaac acaggcaatc
    55081 ctataaaagt gcaaattgag gacacaaatc aacaaaaaga aatcgaagag tttaatacta
    55141 ataatgacat agatgggtta aatgctgaac tctggcttga tatggataag tatgggagag
    55201 cctatgagat tatctatcga gattcagatg atacagatta tgttgatttg gctaatgtat
    55261 ttgaaacgtt tgttgtatat gatactacag taaaacgaga gcctattttg gctgtacggt
    55321 atcctaagac aagattcaac aaggatgctg ataaacagta cattcaacca atcgtataca
    55381 caaaagaaaa aagtatcact tatgatgaga cgacactaac agcaattgag ttaaaaaatc
    55441 cccaggatga accgcatgaa tataaagagg tacctattac agagtattct cctaatcgtt
    55501 ttcggatggg cttgtatgaa gatgtactat ctttgattga tctatacgat gcagggcagt
    55561 ctgataccgc caactatatg actgatctaa acgatgctct tctagttatt agtggtgata
    55621 ttgaagcagc aggactatcc acagaggacg ccatcaagca gaaagaagcg aatatgcttt
    55681 tgcttgagtc tggaactgat gtgaacggta ataaaacaag tgtgactgca ggatatattt
    55741 ataaacaata tgatgtgagt ggtgtagaag catacaaaga cagagtgcgc aaggatattc
    55801 acgaaatctc aatggttcct gatcttacag atgacaattt ttccggagtg caatcaggag
    55861 aagcaatgaa atataaattg tttggatttg aacaaatgac ggcaacaaag caaaggctat
    55921 tcaaaaaagg tcttatgcgg cgttatcgcc ttttatttag cttaaaatca agtatttctg
    55981 aaatggataa ctccgatttg aaaggcttcc gtgtaatatt tacgcctaat ctacctaaag
    56041 ccattctgga agagttgaaa tctttggttg atgctggagc tgaactcagt caagagacga
    56101 ttttaggact cgcttctttt gttccagatg tacaggcaga gttgaaacga gtaaataaag
    56161 aaacgcaaaa gcagattggc atttttgatt cagatggtga agaagtaatt tacaacaaaa
    56221 aagatgaaac aggggagtga ttaaatgaac tcccaagaat attggatcaa acgggaaaag
    56281 gaatggcaaa agcaacaaat taaagatgat aaaaagcgca tggcagaaat taaaagtcgc
    56341 atgcaatacg cacaagatgc gatacaaaaa gaaatagacg cgcagtggga cagtttctcc
    56401 aatggtcaga aaatcactcg tagcgaagcg atgaagcgtg ctagtgaaat ggatgtcaaa
    56461 gcattcgctc gcaaagcaaa gaagtatgtc aaagagaaag atttttctcc tacagcaaac
    56521 caagaattaa agctatacaa tcttacgatg cgtgtaaata gattagagct cttaaaagct
    56581 aatatcggac ttgaattgat ttcactgttt aatgaattgg ataagtactt ttcaaatgaa
    56641 ttaacaaaag cgggtatgga tgaactaaag cgtcaagcag gaatacttga aatgacaata
    56701 gctgaaaaag gctatctgaa attagtggaa catgtaataa atagctcatt tagggctgat
    56761 ggatttgcaa catttagcga acggctttgg atgtatcaag cagaattgaa agccgatttg
    56821 gataagttac ttgttcgaag tgtgacaatg ggtcgtaacc ctaagcagtt ggctccggaa
    56881 ttaagtaagt ttttaacaga agaaggacga gagaatacta agtttaatac acaacgtttg
    56941 atggtaaccg aaataacaag aattcaaagt ggtgtacaga aggaaagtta tatagatgcg
    57001 gatattgaaa aatatggatg ggtaactgaa cctaacgctt gtcaattatg taaaagcatt
    57061 gccgctgatg gtccatattt agtaagtgaa atggaagttg gcaaaaatat gatgccggta
    57121 catccttttg atagatgttc tacttatccc attgtggatc gctaaaagtt gatagtcgat
    57181 aaatatagga gtcactagcc aattcgctaa cggcttttta atatgccttc ttactgctta
    57241 caggcattaa agagaaagct gttccgactg actggcgtaa ctagttaaat tatcgggtaa
    57301 cggcgtaacc gtggaggatt aatcatgaaa aaacgtttat ttatgccaat gaacttacaa
    57361 tttttttctg aaccaggaga cggtggatct ggtgatgagg gacaaaaagg aaacctacca
    57421 gctggctcac aagagacacc gcccacagca aaagaagaaa acaatactgg caaaacattt
    57481 tctcgtgatg aagtagcgaa aatgattgct gctgagacga acaaagctaa agcagcgtgg
    57541 gaaaaagaac tagaagcaaa aaaagaagaa gctaaaaagc tggcaaaaat gaatgcggaa
    57601 gaaaagctac agcatgagtt ggaacaaaaa gaagctgaaa tcgctgaatt aaagcgtgga
    57661 caggcattat ctgaaatgac gaaagaagct tctaaaatgc tgacagatgc aaatttacca
    57721 cacgatgatg atttgcttgg gctgattgtt tctgatgatg cagatgccac aaaacaagct
    57781 gtagcagtca tcactaactt tgcttctttg attaggaaag aaaacgcaag acaaacacca
    57841 ccaaatgaag gtggacaatt tacagcatcg aaaaatacta aagaaacagt ggctaaacta
    57901 gctgctaaaa atcgaattat caaataggag gaaaacttaa tgaaaaagaa acaactttta
    57961 ccaatgaact tgcaaatgtt tgctcaaaca tgggatccag ataatgtctt ggtatatgaa
    58021 acgaaagagg gaaaaattcc tgataaatat aatacgctca ttttgagtga agttatggaa
    58081 aattctaaga tcatgcagtt agcaaaatac gaagaaatga ctgacaaaga aaagaaattt
    58141 gaatactttg cagaaggacc aggcgcatac tgggtgggtg aaggtgaaaa aattaaaacg
    58201 tctaaaccta aatggatgca agctacgatg actgcaaaaa aactcggtgt cattcttccg
    58261 gtttctcgtg aatatttaaa ttataaatta tcagatttct ttgaggagat gcagccaaaa
    58321 attgctgaag ctttctataa aaaatttgat gcagctgcct tattaaataa agaaaaccca
    58381 tttcctcagt cactagacga atcagttatt agtgcgggga atgtggttga aggcggattg
    58441 acttatgata atatcctagc cttagaagac aaattagcag aaaatgaatt tgaacctaat
    58501 gcgtttattt caaaccgaaa aaatcgtaca gaattacgtt ctgcagctca aacagtcggg
    58561 tcaaatgttg agtttattta tgatcgctct gctaatacaa ttgacggatt accagtagta
    58621 gaccttaagt ctttagataa aggaactctt tacgctggag actttaatta catgttttat
    58681 ggaatcccat ataatatttc atttaagatt tctgaagaag cccaattgtc tactttaact
    58741 aatgaagatg gaaccccagt taacttgttt gagcaagaac tgattgcttt gcgtgcaaca
    58801 atggatgttg gatttatgat tgtaaaagat gaagcatttg ggaagatttc cccaaaagcg
    58861 taacgcctgc taccggtatt gtgccaaatc aaaagacatg gaccggtaaa gtaggcgata
    58921 ctaaaacatt tactatttca gctgtgcctg cagatgctag cgatgcagtt actgttgttg
    58981 cagctactac agcaacttca agtgatggag ctatcgcaac agtgaccaaa aatgaaaatg
    59041 gtggttttga tggaacgatt gcagcagaag gatcagcaac attcacattt acttctggag
    59101 aattcactac ttcaatcaat gtgacaggtc aacctgctag ttaggaagta aaaatatgac
    59161 gattgcagat gatattaaaa aacttcttaa aggaacaata gatgaaaagc ttgaagttat
    59221 tgagcgaaga acgaatgagc gtatgaaaac cttgttaaat acgcaagaag ttcctaaaga
    59281 atttgaaaca gttgtatatg aagtatcgtt gaaaagattc aatagaattg gtcaagaagg
    59341 tatgcagtca tattctcaag aaggtttatc tatggctttt cctgattcgg atttttcaga
    59401 gtatcaaaat gagattgacg aatttaagcg taaagatcag gaagagttgt acaagccaaa
    59461 gcgagggagg tttaaattta tatgagattt acagatgaaa ttatatttgt taaacgttca
    59521 tctgactcta aatatgatcc agatctcggt gagtgggttg aaggcaaacc agaaagaaca
    59581 agaacagagg caaacgtgac agatattggc actgatagaa gtgtgactat ttttggtagt
    59641 gtggaagaag gggcgaaggt cattagaacg cagcctcttt tttctatccc tacatttgac
    59701 tatatcgaga ttgaaggaaa ggcttggcaa caaacaacag ctagaaatcc agcatataga
    59761 aatagtttaa ttgtgcaaga ggtggttctt gatgaaggcg caacttgaat ataaaggaat
    59821 cgatcagctg atgcgacatc tgaaaaaagc agcaacgctt aatgatgttc aaaaagtcgt
    59881 taaaagtaat actgctgaaa tgactgaacg aatgcaaaaa ggtgcaccag tggatacagg
    59941 atacttacga agatcaataa acatgaatct tttagaagct ggtttaactg gtattgtagg
    60001 accgacagca gattatgcac cttatgtaga atatggcact cgatttatgt cggcacagcc
    60061 ttatgttaga ccagcgttta attaccaaaa agtcaaattt atggctgaaa tgaaagcctt
    60121 ggtgaaatga tgattaagac aagagatcaa tcaatttttg atgaactttt taaaatatcc
    60181 caagaaaaac taggatacaa aacatatgat tacaaacctt tagataatgt tggttatcct
    60241 tttgtggaat ttgagaacac tcagacaatc catgaagtaa ataaaactga cattaaaggg
    60301 tctgtgattg tggttttatc cgtttggggg ttacagaaaa aaagaaagca ggtgtccgac
    60361 atggcatctg ctctttttaa tgaagctaga ttaatagaag ccacagaagg ctattattgg
    60421 gctttgaatt atcaagcaag tggaattcaa gtgatggatg atacaacaac gaatacaccg
    60481 ctaaaacgag cggttgtcac acttgaattt agaattagat aggaggaaga acatggaagc
    60541 attaaaaggt attgatgtca ttttgcttta tcgcttattg aaaaaagaaa ctcaggaagc
    60601 tgcttggaaa atggcatttc aaacagaaca tgaaaatgga ttatcaagag attcagactc
    60661 tacagtgaca aaagacggaa acgttcaaag tttaagcccg gttgaatatg atttttcggc
    60721 tacttcaata gttgctaaag gagattctca tgtagatgaa atgaaacaag ccttattaaa
    60781 tggcgatatc attgaaattt gggaaatcaa caaagcagaa cagggaacag atgataatgc
    60841 aaataagtac aaagctactt attaccaagc atatgtgtct gaatttactc catcggctgc
    60901 tgcagaggat aacgttgaat taaatttatc atttgcagta aatggtgttg gccaagatgg
    60961 ttatgcaacc ttgacagaag atcaagccga tgttgttcaa tatgcattca aagataccgt
    61021 gaaagcaact tcgacaggag cataagaggg cttagatgct ctctttttta ttttaggagg
    61081 atgaaaaaca ttgaaattaa aaattaaagg taaagaatat tcgtttaaat ttggcactaa
    61141 atttgtacgt gaattagaca aagtgatgcc tttcatcgat ggaaatatgg aattcggaat
    61201 gggactctca gcaaaagtct taccggaatt acgttcttat aatgtcaaca cgttgtcacg
    61261 agtcttagaa atagcaaata gaacagaaga agaaactatt acgttggatg aaatggatga
    61321 ttacatcgat gaagttaaag acatcgaaaa attgtttgat gaagtcctaa aagaattggc
    61381 ggagtcgaac gcgggaaagt tagcggtccg aaacctgaat cagaaattga aagaagcgga
    61441 aaaacaacaa gcggaataga ttctgcactg gcatacgaac aaattcttat caactctttt
    61501 cgatatttgg gaataaacaa tatctcagat atcgaaagaa tgactttata tgaatacaac
    61561 attcgtatga ctgcagccca gttatcttgg cttgacaaag aaaagttgat tcacgaatta
    61621 gcgtgggcaa atcagcaagt ccaagcggag aaaaaagtag gcaaaaagac agttcctgta
    61681 tatcgatcct ttgaagaatt ctttaattat caaaaaatcg aagattcaat catgggagtt
    61741 tccgaacttt caaaacaaga taaaaaattc caaagcttac taactaaagc taattcttga
    61801 ggaaaggagg aaaaacatgg aacaattttc tgttgaagcc ttattaaaag ccacagatag
    61861 tggatttgta aagactttta aagatgcgca agatgctgtt aaaacttttg aaaagaattc
    61921 aaatagtatg acaaccgctg ttggtaaagt gatgcaaggt actggtgccg caatgacaaa
    61981 gtatattacc acacctctta taggagtagg cgtagcagct gctaaagttg gtggtgactt
    62041 tgaagcgcaa atgagtcgtg taaaagctat atcgggagca actggcgaca cattcgaaca
    62101 gatgaaacag caagcgattg atctaggagc aaaaactgct tttagcgcaa aagaatcagc
    62161 cgccggaatg gaaaacttag cttctgctgg atttaacgcg caagaaatca tgaaagcaat
    62221 gccgggtctt ttagacttag cagctgtatc tggaggggat gtggctctag cttctgaaaa
    62281 tactgctact gctttgagag gatttggttt agaagcaagt gaagcaggac atgtcgctga
    62341 tgtatttgct cgtgctgctg cggatacaaa tgctgaagtt ggagacatgg gagaggcatt
    62401 gaagtatgtt gctcctgtag ccaattcaat gggtatttct ttggaagaaa ctgcagcagc
    62461 tattggtatt atgagtgacg caggtattaa gggttctcaa gcaggtacaa cgttgcgagg
    62521 agcattgtct aggttagcaa ggccaacaaa ggctatgcaa gatacaatgg ataatttagg
    62581 tgtttcgttt tatgatgctg acggtaaaat gaaaccttta aaaactcaag tagaattact
    62641 taaaaaagct tttgaaggcc tgacgcctga acaacaacaa aatgctttag taacactata
    62701 tgggcaagaa tcattatcag ggatgatggc tttgattgat aaaggacctg attcattggg
    62761 caaattaaca aaatctctga aagattctga tggtgcagct gacgatatgg ctcggaccat
    62821 gcaagataat atgaattctt ccatcgagca aatgtttgga gcttttgagt cagcagctat
    62881 tgtaattcaa aagattctag caccatccat caaaaaagta gcagatgcca tatccggctt
    62941 agtagaaaaa tttgtaagtg ctccagaatc aactcaaaga ttagtagtgg ccataggagc
    63001 aatcgctatt gcaattgggc caatattgta tgcattagga atgctggtta aagcgtttca
    63061 aaccatgaaa gtggggttag gtgtattagg taacggaatc tctttgttca agaaattagg
    63121 ttccgccata ggttttctta ccagtccagt cggattggtt atagctgcgg tagcactact
    63181 tgttgtaggt ttcatctatc tttggaatac gagtgaagat tttagaaact tttggattgg
    63241 cttatgggag ggaatcaagt ctgctgtaag ctcggcagta gaatggattc agaatgcatg
    63301 gaaatctaca ggagaatggt ttaacaattt atggaagtcc attaaagaag gtgcagacaa
    63361 tgtttggact acaattcaag aagctcctgg gaaagcggca gattggatca agaataaatg
    63421 gactgaaaca aaagagttct tttcgagtat atgggacggc atcaaagaag ctgccagttc
    63481 cgcttgggaa ggaattgtaa acattctagc accgtatgtt attgccataa aaaacgtttt
    63541 tcagccaatg attgatttct ttacgaacct atggtctcaa attggatcaa tcgcaggctc
    63601 tgcatgggaa attataaaaa ctgctgtaat gggtccaatt ctgcttttga ttgatttgat
    63661 aacaggcaat tttaatcagt taaaagaaga tgcttcgatg ctgtggacta cattaactac
    63721 aaatatccaa aacattatca cgacgtttgt agatatagtt gttggttatt acacagcctt
    63781 aaaggatact gtgataaata tctggaatgt gttaacttct accatcaaag atgtgtggaa
    63841 ttcttttact acatggatca aagagacaac taataatatt gtaaatagta ttagacaggg
    63901 atggaataac ctaaaacaag ggacaatcga tctgtttaat aatatgattc aaggagcgaa
    63961 agatttatgg aattctttca aagcttggtt tattaatcta gttattggaa ctaaggataa
    64021 catcattcag ggatgggaaa acctaaaaca aggcactata gatactttca acaatttagt
    64081 aagtggcgct caagaagtgt gggataattt agtaaatgct gttagtgata cggttgatag
    64141 agtaactggc tggtttgata acttgaaaaa tatcgattta ctagcagccg gaaaagctat
    64201 catggatagt tttctagaag ggttacaaaa tgcatggaaa tctgtgcaag attttgttgg
    64261 aggtattggt gactggatta gggaacacaa aggacctatt cgatacgata aaaaattgtt
    64321 aatcccagct gggcaagcaa tcatgaatgg actaaatgca ggtttaacta atggctttgc
    64381 cagtgtccaa agcaatgtag gaaacatggc taatatgatt gcagatagtt ttactcgtac
    64441 acctgatatt gatctttcag cgaatttaaa aaatgcaaat agaaatttca caacacaaat
    64501 agagcatagt gttaactacg gcaaaaataa acgtcctgca gttttcaata ttcgcttagg
    64561 aaatcaagtg tttgaagcgt ttgttgagga tatttcaaac attcaaggta aagaggcgga
    64621 tattaattta ttgttctaga aagtgaggga aatatgatgg agtggcataa tccaatgtat
    64681 gaattcagag acacggttaa aaacgacagt cagaaaacat ggataccgac atctgcattg
    64741 aattatgatg ggaagtttat cgagaattat atagaagggt accagacttt gtatgtggaa
    64801 ggtagagaaa tggtttcttt agagattgag agtgaagcgg tgagcatagg tgttcgtatt
    64861 agttctcaaa gacttccaga gaggatttta actatacatt ttaaattaga agaaaagaat
    64921 cctattgaat tccaacgaag ctttaataaa ttgatgaggc tgctttacag ggataaagat
    64981 gtagaaattc actttaacga tgagttggat atgtattatt acggaaggta tcagacctgt
    65041 gatgatattc caggaaacgt tcatagtgta atatctagtt tctctataat ctgttctgat
    65101 cccagaaaat atacacgtat atttgaaaca aacggcatag tctcagaata tcttccgtat
    65161 gaagtagctc cgatttcaat tagtttaaag gctaataatg atgggaactt aagtattaca
    65221 aatggccgtc aaaatattag tgtgactaac tcaatgataa aaaaaggtga ctttatcgag
    65281 atggacatag ctgagggaaa agtttttgta aatggagtga ataaaacaag aattcttgat
    65341 cttactagct catttaaaaa ctttatggtt agaaccggtg atctaattaa gtgtgataat
    65401 ggcactccct taatacgata tagaggagtg tggctgtaat ggacaaagat gtttattttt
    65461 tcgatgatag ccaaaagctt ataaaaatag taggggaaga taaacttttt tcggtagttc
    65521 aagaaaagga aattacacca agtaaagatg agttaattaa tgataaatta gcagttagca
    65581 tggagtttga cgatgaaatt aaagagtcag cttatatggc ggttcgtgaa agcgagtcgt
    65641 ctttttctat gtataaaatt atcggaattg ctgatccggg ttcattgttg atattcactg
    65701 ggattaattt tgggcctgat gaattggatg cttatatcat taatgatatt cgtccggcta
    65761 acgagttttt tcagaaaacc atccagagag tcatagattt cacattaggt gagtggcgag
    65821 ttggccactt agattcaact ctgccagcgg tttctatgac tttttactac tgtagtatcc
    65881 gtgaagcctt aaaaaatcta caaacgttag gatgcgagat tgtttttagg tgcaatctaa
    65941 gtggagaagg aatcacagat aaatggatag aagtttacaa gcagattggc gaatacagta
    66001 atgagcgata tgagtacggt gataaagcct tgacaattga aaaagaagta gatcgaagta
    66061 acatctatac ttctctaatc ggacgcggcc gtggtgaaga ggttggagat ggttatggtc
    66121 gtcgtattga gtttgatcaa gtatactggt ccaaatcaaa aggggatccg ttaaacaagc
    66181 ctactggtca gatatatttg gaaatccctg agatgactga aaaatatggt attcctacta
    66241 aaaacggaaa acgtcgtaag cgtgagaagg taattatatt cgaagactgc gaagatcctg
    66301 ttgagctaat tcagcttacc tatcaagaat tggttaactg ttcacgtccg ctagttcaat
    66361 ttaaagcaac tattttcgga gcagatagtt taggtaatat tatacgtatt catcgtgatg
    66421 accgcggcta tcattacgag actagaattt tcagtgtgaa aattgatcga ttaacaggaa
    66481 aagtcgaaac tggcttaggt gataatttaa atacttcatc aacacgtcaa gcttcaaata
    66541 ctcaaactgc catacagacc cttgacgaga agaagatgac cttttatgag tctaccgaag
    66601 tttctaaatg gcaatcggat atcatccgtg gggcaaaggg tggatcaatt attatgatga
    66661 acccttggga tactggtaaa ggagaaagtc gtcaaccata tcagatggtt tggatgaatg
    66721 gggatagcat tgaaacttct aatcattttc ttgtagccaa ttcggaagga atcggattta
    66781 ttgatggaaa attcaatgag gcaaatttta aaacagcatg gacgattgat ggaaacttta
    66841 atgcaaatta tatccagtct ggacgtatta gagcagatat ttttgaaact tcatttaacg
    66901 ctgttggtga tcagctcaag ttagtaaaag gagctttaca aattgtgaac agcaacaaaa
    66961 aaatcatgga attaaccaaa aaagggatgg agttttggaa caccaaagaa tccatcggca
    67021 caatcggtac gactgattct gcaggcaatc cttttcctgg cgcatccact cctacaccgt
    67081 tagaagataa ttcgttagtc attcgaacaa acggcgatgg aaaatatatt ctcatttcac
    67141 caaaagaagg aaaaggttgg gtaatacttg ggaatggaac ttctatatta tttggaagtt
    67201 taaacctaca ggaaaagcta aatgcctttg gtgatgcgga atttatgaaa aatgtcaata
    67261 ttcgcggaaa actcacaatt aacggacaag aagtattccc tggacaaggg ggaagtggga
    67321 ataacggcgg gggaagttgg aatggaatgt atccaccaga gttaactagt caagcggaca
    67381 aatttgcttg ggagctatgg gttatgcttc tttctagagg ttattccaaa gcatccattg
    67441 ctggaatcct tggaaatgtt caaggagaag ccggtgctgc aatgaatcca gatattgcac
    67501 aagttggcgg tccagcctat ggaatcgttc aatgggatgg ttcagcatat cctttggttc
    67561 ctccagcaac atgggatggc aggacttatg ttcaaaacct gatgagagct gcaggaatta
    67621 cagaagatta tcgaacaatg tcagctcaag gaaagttatt agattggaca atgtataacg
    67681 gtcaatggtt aggaattgtt caaccggcaa gtgtttctgg atttaaagta atgactgatc
    67741 cagcagcagc tgcttataca tttgaacgaa actatgaaag gccagccaca actcatccag
    67801 aacgacaagg atgggcagtt aattggtata acaaatttaa agatcttcaa gtcccatctg
    67861 ctggcagtat tctcagtaca gccaaaagct tgatgggtta tttccattac tcgcaaccgt
    67921 tacgttggaa ttttggtagc gtcgataatc ctgatcgtaa tgggtatgct gactgttctt
    67981 cttttgtgtg gttggctttg acaaaagcag gatataaaac cgcaacacgt gggactctgt
    68041 ggtacacagg ttcaatggcc gcagatgcaa gaggggcacg tcagtatctg actgaaatat
    68101 ctccaaatga agcgaaagcc ggagatatca ttattgtcaa ccaaggagcc ggtgctggta
    68161 acgatggaca cactgctatt ttagcagagg attggaaggg atatagcacg tctatcgttg
    68221 aaatgggcgg tatgaattcc aatggtgtag gtatcggtcg cgtcgattgg tccttcgggt
    68281 atttattaaa cggtggcgat gtttgtctcg tcagagcgaa gaaatagagg tgattttgtg
    68341 atcgaagaaa aaggattaaa tcatttgaaa agtttgttga atcaacctat cggaaaccat
    68401 caatgttatg cattatctgc ggaatatgcc ggtgtgatga ttggtcctga catgggggca
    68461 ggtacacaat acgagatcaa agtacgtcac ggcaatgtgt tttccgctgc ggaaattgga
    68521 cgagcctact catgggcatt gtatttatgg acggttattg ttcatcccga gtatgaccaa
    68581 ctagttgttg gctcaattat caattgggaa agaaacgcaa aaatcagtga tacatttgaa
    68641 agccatgaat attacggcca cacaggtgta atcaaaggtc tagaaaatgg gcgtattcaa
    68701 acctatgaac aaaatgcaga atcaggtgga attgtggcgg aatatgatcg tgaattcttc
    68761 ggatctggtc agatagcttc tatttgtatc ccacctgatt ttgagaaagg agtggtaatt
    68821 aatggcaaag tggaacgtag tactcagcac aactgaacct tataactatg tcggtatgat
    68881 tcaggtacgg caaggtaata agaattcaga ggttatggaa gcaaccatca ctgaaaatgg
    68941 aatgccctat gatctaactg gttgtaaagt ctattttgaa tcagttgtcg gagacaaata
    69001 cccagttcaa ttaggtacta aagtcattga tgcaaaaaaa ggaaaaattc agtacacatt
    69061 tgatcaatat tcgatgcaat gcctacatcg ccaaacagca gattttatca tttataaaga
    69121 tgatgagtta attgctacga cgcaagattt ctcttatttt gtgattaaag ctgtctcaaa
    69181 aacagagggt gaaatgggat cgtattggca gacagtcgaa gatttaattg cggatatgtc
    69241 agcttttatc aatgaaaaca aaggtgactt cacagattgg atgaatgcac gtaaaaagga
    69301 atttgaacaa tggcgacaag accaacaaaa tacatttgag gcatggagag aaggacaaga
    69361 aaccgattat ttaaaatggt ttgaatcaat caaagatatt ttgaagtcta tcgatccagg
    69421 tggagtaatg ttagccgaat taatggatgc acgtgttgat attcaaggag ttcgtcatgc
    69481 gtctatttca gagcgcttgc tggcagatat ggattatcta tatcagaaat tacgagcaac
    69541 acttttcacg attgaatacg gtgagattga agtgactgat attttgcagg atgatctctt
    69601 ttcagataat cacgaagtcg aaaaagttgg aactgtagaa ttcccgattg aagaaggagc
    69661 cttgatcatc gcaaccgttg atgatccaaa gcaaaatgtg ttcactcttg agaaagttgg
    69721 ggtgatctaa tggctaaaac taaacgaatg atggaaacgg atgaaaaaac aggtgtacaa
    69781 cgccaattct ttccaatcac acatgcttcc gcagttcttg ggttagaaga aataatagca
    69841 ggagaagcaa cagttttatc tgttaatggc aaaattggag ccgtcgtcat tactaaagaa
    69901 gatttgggat tagagaatgt tctcacagaa ttaccctatg caagtgaaga agatgacggc
    69961 attatcacgt cagaaatgta tcaaaaaatt ttaaacagtg gagaaggtga ctacgtgttg
    70021 ccagttgcca ctatcgaccg tttgggtggc ataaaaattg gtgaattatt gacgattgat
    70081 gagacaggaa aagtctctgc agtcagacaa tctgatgtca atttttcgct ggagttaaaa
    70141 gaaaaactcg attcactgaa aaactatact gcaggagaaa acatcactat tgatgaagat
    70201 ggaaaaataa atgcagaagt gactggtttt tacgttttac ccactgcctc cgaatttgta
    70261 aaaggtggta ttcgtgtcgg tgaaggttta acgatgactg atgatgtttt atcggccgat
    70321 aagcaattca actatactgc cggagctaat atcagtattt caaacacagg agtaatctct
    70381 gcaacaggtg gtggagaagg tggcggcgtc actcaagaat atgttgatca aaaaatgagt
    70441 gaagcttatc aaaatgcaca agcttataca gattccaaaa taccaaatgt atcgtttgaa
    70501 aaagtagggg aggtatagac aaatgacaga tattgtaaaa gtaaaacaga atgatgttca
    70561 ggtttaccct caaacccatt gggatgctgt tgagggtaaa cccgaaacta tcaagggaga
    70621 taaaggagac cctggacagg ctgccacaat tactgtaggg acagtaacga gtggtacaac
    70681 agctagtgtc acaaatgctg gtactgcaag tgcagcaaag tttaattttg tattgccaaa
    70741 aggtgataaa ggggacaaag gcgatcctgg agccaatgca acaacgacag ctgtggctac
    70801 gacgacagca aatggtttga tgtccaaaga agataaagtg aaactcgatg gattagccaa
    70861 tattacattt gagaaagtgg ggacggttta atggctgata ttgtgcaatt aaaagaagac
    70921 ggagttgcta agtatttgaa aactcatgcc aaaggaattg atggtgtgga gggtgtttta
    70981 gtaaaagcca caggtaatga aacggtctta ggaacgaaaa attttaaaga cggattgcaa
    71041 ttcaatggat tgcctgtgca agcaggtatg atcgagcgag ctatcacact agctgatcga
    71101 agtgatacaa caaacgtaac tgatgtgaat ggaaaaataa tcagaatcgg aaacatcgta
    71161 tttcttactt ttaattttaa atgtggcaca tggcccgaag gatcagaaac tcgttggatt
    71221 ttaaaaatcc cggacggttt caaacgtgat caaggctatc cagcgcaaac cgcgctttca
    71281 ctagttagaa atgcaagtca gccagcggat gcacgtgcat tcattgatca aagtagcatc
    71341 atacaagcca aatcaggttc aggtagttca tatatttcag gtatgtggat cactcaagat
    71401 ccttggccgg cttaacagat tactaattgg aggaagagta aaatgaaaac aatttataaa
    71461 gtattgtatc caatgggata tgaagaacat caagtagaag ataactttcc aacatcttta
    71521 ccatttgtcg aagttccacc tattttgttt gaaaagaagg aagatgaaac ggatgaaggt
    71581 ttcggaagaa gacaacagtc gcaatttttt aacttcactg aaaataagtg ggaagaagca
    71641 gttacacaag attattctaa aaaattagaa ctactagaaa atttatctat aggtttacag
    71701 gtagataata ctgcattgaa aaaatcaaat gaagagttaa cggaaaaagc agattcgatg
    71761 gcgcagttga acgccaaact gatgcttaat gatttaacaa ttaataaaaa aattgaagca
    71821 atagaaaaac aaattggagg tgcttcataa tgtttagttt tagcgatgtg aaaatgatgt
    71881 atgattgggg ctgttttact gacgatcaag ttcgacaatt cgttccacta tgcattacag
    71941 acgaagaagc agataaaatc attagcaaag aagagagcgc atcttaattg atgtgctttt
    72001 tattttgatt caaggagttg tcacatgatt aatttagggg aatggggagc gatagcagga
    72061 tcaataaccg ctatcgtttc tttgatttta ttagtaatta gaccgattgt tgcatcattt
    72121 acaaaaatta cgaaaacact atcacaagtg agttacaact tggaactatt aacaaaagat
    72181 ttagaatcga gcaaatcaga tcgattgatg attcatgaag aactcaagaa acacgatgaa
    72241 agattagata cacatgcaga aaaattggta gaacacacac aacaaattaa aactttattt
    72301 agagaaagat ctaggtaaaa aagaaaggag ttaagaagaa atgattttac ccgataagta
    72361 ttatcaagtc attaaatgga cagttttaac agtattacca gctgcttctg tgttagtagc
    72421 tacgttaggc aaagcatatg gatggaatgg aacagatatg acagttctga ctatcaatgc
    72481 agtagcgac
//
LOCUS       DAIGUC010000005        72431 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.005, whole genome shotgun sequence.
ACCESSION   DAIGUC010000005 DAIGUC010000000
VERSION     DAIGUC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.005"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(159..443)
                     /locus_tag="NOB46_000318"
     CDS             complement(159..443)
                     /locus_tag="NOB46_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057295.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(461..1351)
                     /locus_tag="NOB46_000319"
     CDS             complement(461..1351)
                     /locus_tag="NOB46_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCI1057296.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1371..1589)
                     /locus_tag="NOB46_000320"
     CDS             complement(1371..1589)
                     /locus_tag="NOB46_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HCI1057297.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1559..3259)
                     /locus_tag="NOB46_000321"
     CDS             complement(1559..3259)
                     /locus_tag="NOB46_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCI1057298.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3526..4299
                     /locus_tag="NOB46_000322"
     CDS             3526..4299
                     /locus_tag="NOB46_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057299.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="NOB46_000323"
     CDS             complement(4380..4949)
                     /gene="thiT"
                     /locus_tag="NOB46_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HCI1057300.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5015..5117)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5123..6094)
                     /locus_tag="NOB46_000324"
     CDS             complement(5123..6094)
                     /locus_tag="NOB46_000324"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI1057301.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="NOB46_000325"
     CDS             complement(6188..7561)
                     /gene="glmU"
                     /locus_tag="NOB46_000325"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCI1057302.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8064..8882)
                     /gene="purR"
                     /locus_tag="NOB46_000326"
     CDS             complement(8064..8882)
                     /gene="purR"
                     /locus_tag="NOB46_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCI1057303.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9049..9873)
                     /locus_tag="NOB46_000327"
     CDS             complement(9049..9873)
                     /locus_tag="NOB46_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI1057304.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9846..10526)
                     /locus_tag="NOB46_000328"
     CDS             complement(9846..10526)
                     /locus_tag="NOB46_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI1057305.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10549..11487)
                     /locus_tag="NOB46_000329"
     CDS             complement(10549..11487)
                     /locus_tag="NOB46_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HCI1057306.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11732..12595)
                     /locus_tag="NOB46_000330"
     CDS             complement(11732..12595)
                     /locus_tag="NOB46_000330"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCI1057307.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="NOB46_000331"
     CDS             complement(12737..15310)
                     /gene="mprF"
                     /locus_tag="NOB46_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI1057308.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFLSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15451..16257
                     /gene="proC"
                     /locus_tag="NOB46_000332"
     CDS             15451..16257
                     /gene="proC"
                     /locus_tag="NOB46_000332"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCI1057309.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16336..17892)
                     /gene="rny"
                     /locus_tag="NOB46_000333"
     CDS             complement(16336..17892)
                     /gene="rny"
                     /locus_tag="NOB46_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCI1057310.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18303..19352)
                     /gene="recA"
                     /locus_tag="NOB46_000334"
     CDS             complement(18303..19352)
                     /gene="recA"
                     /locus_tag="NOB46_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCI1057311.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19461..20702)
                     /locus_tag="NOB46_000335"
     CDS             complement(19461..20702)
                     /locus_tag="NOB46_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCI1057312.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="NOB46_000336"
     CDS             complement(20942..21520)
                     /gene="pgsA"
                     /locus_tag="NOB46_000336"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCI1057313.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21729..22652)
                     /locus_tag="NOB46_000337"
     CDS             complement(21729..22652)
                     /locus_tag="NOB46_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057314.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23391..24677)
                     /locus_tag="NOB46_000338"
     CDS             complement(23391..24677)
                     /locus_tag="NOB46_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI1057315.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24670..25938)
                     /locus_tag="NOB46_000339"
     CDS             complement(24670..25938)
                     /locus_tag="NOB46_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI1057316.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26190..26651
                     /gene="mscL"
                     /locus_tag="NOB46_000340"
     CDS             26190..26651
                     /gene="mscL"
                     /locus_tag="NOB46_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCI1057317.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26710..27156)
                     /locus_tag="NOB46_000341"
     CDS             complement(26710..27156)
                     /locus_tag="NOB46_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1057318.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27249..27494)
                     /locus_tag="NOB46_000342"
     CDS             complement(27249..27494)
                     /locus_tag="NOB46_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCI1057319.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(27608..28186)
                     /locus_tag="NOB46_000343"
     CDS             complement(27608..28186)
                     /locus_tag="NOB46_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI1057320.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(28263..28793)
                     /locus_tag="NOB46_000344"
     CDS             complement(28263..28793)
                     /locus_tag="NOB46_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCI1057321.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(28797..29657)
                     /gene="rlmB"
                     /locus_tag="NOB46_000345"
     CDS             complement(28797..29657)
                     /gene="rlmB"
                     /locus_tag="NOB46_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCI1057322.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(29650..30045)
                     /locus_tag="NOB46_000346"
     CDS             complement(29650..30045)
                     /locus_tag="NOB46_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCI1057323.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(30042..31454)
                     /locus_tag="NOB46_000347"
     CDS             complement(30042..31454)
                     /locus_tag="NOB46_000347"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCI1057324.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(31451..31987)
                     /gene="cysE"
                     /locus_tag="NOB46_000348"
     CDS             complement(31451..31987)
                     /gene="cysE"
                     /locus_tag="NOB46_000348"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCI1057325.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(32073..32312)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32309..33769)
                     /locus_tag="NOB46_000349"
     CDS             complement(32309..33769)
                     /locus_tag="NOB46_000349"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCI1057326.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(33939..35096)
                     /locus_tag="NOB46_000350"
     CDS             complement(33939..35096)
                     /locus_tag="NOB46_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCI1057327.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(35130..36500)
                     /gene="radA"
                     /locus_tag="NOB46_000351"
     CDS             complement(35130..36500)
                     /gene="radA"
                     /locus_tag="NOB46_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCI1057328.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(36563..37090)
                     /locus_tag="NOB46_000352"
     CDS             complement(36563..37090)
                     /locus_tag="NOB46_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCI1057329.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            37320..38126
                     /gene="proB"
                     /locus_tag="NOB46_000353"
     CDS             37320..38126
                     /gene="proB"
                     /locus_tag="NOB46_000353"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCI1057330.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            38123..39370
                     /locus_tag="NOB46_000354"
     CDS             38123..39370
                     /locus_tag="NOB46_000354"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCI1057331.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            39446..39790
                     /locus_tag="NOB46_000355"
     CDS             39446..39790
                     /locus_tag="NOB46_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057332.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(39907..40233)
                     /locus_tag="NOB46_000356"
     CDS             complement(39907..40233)
                     /locus_tag="NOB46_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057333.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(40606..41807)
                     /locus_tag="NOB46_000357"
                     /pseudo
     CDS             complement(40606..41807)
                     /locus_tag="NOB46_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            41924..42439
                     /locus_tag="NOB46_000358"
     CDS             41924..42439
                     /locus_tag="NOB46_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1057334.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(42638..43084)
                     /locus_tag="NOB46_000359"
     CDS             complement(42638..43084)
                     /locus_tag="NOB46_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI1057335.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(43131..44609)
                     /gene="msr(C)"
                     /locus_tag="NOB46_000360"
     CDS             complement(43131..44609)
                     /gene="msr(C)"
                     /locus_tag="NOB46_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI1057336.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(44963..45592)
                     /locus_tag="NOB46_000361"
     CDS             complement(44963..45592)
                     /locus_tag="NOB46_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI1057337.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(45576..46040)
                     /locus_tag="NOB46_000362"
     CDS             complement(45576..46040)
                     /locus_tag="NOB46_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1057338.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(46527..47795)
                     /locus_tag="NOB46_000363"
     CDS             complement(46527..47795)
                     /locus_tag="NOB46_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI1057339.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(48026..48763)
                     /locus_tag="NOB46_000364"
     CDS             complement(48026..48763)
                     /locus_tag="NOB46_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1057340.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(48830..49399)
                     /locus_tag="NOB46_000365"
     CDS             complement(48830..49399)
                     /locus_tag="NOB46_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI1057341.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            49527..50399
                     /locus_tag="NOB46_000366"
     CDS             49527..50399
                     /locus_tag="NOB46_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1057342.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            50741..51613
                     /locus_tag="NOB46_000367"
     CDS             50741..51613
                     /locus_tag="NOB46_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1057343.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            51610..53568
                     /locus_tag="NOB46_000368"
     CDS             51610..53568
                     /locus_tag="NOB46_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1057344.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(53819..54670)
                     /locus_tag="NOB46_000369"
     CDS             complement(53819..54670)
                     /locus_tag="NOB46_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1057345.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            54793..55260
                     /locus_tag="NOB46_000370"
     CDS             54793..55260
                     /locus_tag="NOB46_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCI1057346.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(55523..56005)
                     /locus_tag="NOB46_000371"
     CDS             complement(55523..56005)
                     /locus_tag="NOB46_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCI1057347.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(56105..56968)
                     /locus_tag="NOB46_000372"
     CDS             complement(56105..56968)
                     /locus_tag="NOB46_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI1057348.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            57566..58414
                     /locus_tag="NOB46_000373"
     CDS             57566..58414
                     /locus_tag="NOB46_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057349.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(58585..58926)
                     /locus_tag="NOB46_000374"
     CDS             complement(58585..58926)
                     /locus_tag="NOB46_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCI1057350.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            59012..59719
                     /locus_tag="NOB46_000375"
     CDS             59012..59719
                     /locus_tag="NOB46_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI1057351.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            59706..60029
                     /locus_tag="NOB46_000376"
     CDS             59706..60029
                     /locus_tag="NOB46_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI1057352.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(60118..61155)
                     /locus_tag="NOB46_000377"
     CDS             complement(60118..61155)
                     /locus_tag="NOB46_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1057353.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(61602..62585)
                     /locus_tag="NOB46_000378"
     CDS             complement(61602..62585)
                     /locus_tag="NOB46_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HCI1057354.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(63001..63771)
                     /locus_tag="NOB46_000379"
     CDS             complement(63001..63771)
                     /locus_tag="NOB46_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057355.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(63764..64699)
                     /locus_tag="NOB46_000380"
     CDS             complement(63764..64699)
                     /locus_tag="NOB46_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057356.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65293..66942)
                     /locus_tag="NOB46_000381"
     CDS             complement(65293..66942)
                     /locus_tag="NOB46_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI1057357.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(67137..68033)
                     /locus_tag="NOB46_000382"
     CDS             complement(67137..68033)
                     /locus_tag="NOB46_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1057358.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(68026..68706)
                     /locus_tag="NOB46_000383"
     CDS             complement(68026..68706)
                     /locus_tag="NOB46_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1057359.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(68707..69489)
                     /locus_tag="NOB46_000384"
     CDS             complement(68707..69489)
                     /locus_tag="NOB46_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057360.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(69482..70399)
                     /locus_tag="NOB46_000385"
     CDS             complement(69482..70399)
                     /locus_tag="NOB46_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1057361.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(70402..70686)
                     /locus_tag="NOB46_000386"
     CDS             complement(70402..70686)
                     /locus_tag="NOB46_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057362.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(71387..72007)
                     /locus_tag="NOB46_000387"
     CDS             complement(71387..72007)
                     /locus_tag="NOB46_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057363.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(72088..>72431)
                     /locus_tag="NOB46_000388"
     CDS             complement(72088..>72431)
                     /locus_tag="NOB46_000388"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057364.1"
                     /translation="NIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQDK
                     KNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQKK
                     RDNNDQYLPKK"
BASE COUNT        20829 a        15442 c        12751 g        23409 t
ORIGIN      
        1 ataccgagaa aatggttttt gaacatcact tattcaaaat aaaaaaagat tgtgacacga
       61 attttgtcac aacctttaaa tgtattccta gagcaaagaa gctaagcgaa gaaatccaat
      121 tctgattatt tattgtattt ctttgttcag catccttgct aaaagcccat attggacaaa
      181 gtattcacta cacccatgat ctcatctttt cgagaacgtg ctttttctgt cggatcttct
      241 acctcttctg tgtcaattcg aacaataaat ttccgattca tcgtcacgta agcaccgtcg
      301 ttgatcaaaa taaacagttc gttctcatta tagtctgcac aggcatcttt ccatacgtca
      361 aagccgtttt tttcagaagg gatatcccgt ttaaccacag tttttccact taattcgtgg
      421 aacgttacgt cataatattt cattatctct acctctttcg tcattcaata ttttgtactt
      481 gttctctgat tttttctaag atcgtcttag actggacgac ttgattttta atttcgattg
      541 catttgattt ggaaccgatc gtgttgattt cccgattcat ttcttggatc aggaaatcta
      601 attcccgacc tacaggacat tgtgcttcga taagttcatc tagtttttgt acatggatcg
      661 ccagacgatc cagttcctcg tgaatatctc cgcgttccaa caagatggct agctccgtca
      721 acaaccgttg ctcatcgact ttcgctccaa gaaattcctc cagctttttt tgatacctta
      781 tttgaaattc cttttcatag atttctacaa aactatcgag tttttttagt acttctttga
      841 attcttcagt attctttttc aacactaaag ctaaagcttg accttctttt tctcgactcg
      901 cctcaataga atcaagtgcg cttttcaatg tatctagagc taactgtgcc aattcttcca
      961 tgctctcttc cggtttttct tctaccgtta cgaagttttc gtccagcgcg aagcgttccg
     1021 ccatccgact aattgacact tgattttgac taccgtatcg ttgttgaatt ccgtctgtca
     1081 attgagtgat aagtgaatca atcaattccc agttgatgac gatctgtttt tcgtttttgc
     1141 caatataagc tagattcaca aatacttcga ttcgaccgcg gcttaactgc tgtttaataa
     1201 gctgacgaaa atcgttttca acaaagttca ggattttagg acttcgtatt tgaacatcta
     1261 gaaaacgctg gttgacactt tttatttcaa tatctaactg atacgctttt gtttcgcgga
     1321 tggctttgcc aaaaccagtc atacttttca ttcgacaggg tccttcctca ttacatattt
     1381 tctattgctt tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc tttccccatt
     1441 ttttcatggt ctggcgccca atctcgaaga tcgaattttg gcgggcgacc attccagctg
     1501 actaggttca gttctttacg ccaccccttg ttgttttctg acaatatagc gatttcttct
     1561 acgatttcat atgaaaattc ttgtgccatg gttgttcctc cttgagataa tataaatata
     1621 ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga tccttgcgtt
     1681 ttccttgtag cagataatca aaataaacag ttttcgtgcg ctcattttgt attttttgct
     1741 ggtattttcg ataccttcgc cattcttcag tacttaattg accaatttgt gccaataaat
     1801 catccggcat actttttata tcttgttggc agatcatttg aatcatcatg tctacttgat
     1861 agatttcatt gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc gccaatccgc
     1921 atgtctctgg tacgaccctg ttcttatata aattacgcag tttttgccaa aattttatgc
     1981 ttttgaaaaa agataattct aactgaattt cttttgttaa gtaagacaaa aatcctcgcc
     2041 agtatgttct tgcaggttta acagaatgaa atgtatacca gttcccatag taatagccta
     2101 atcgtttttt catttccaga tagcctaatt gtaaatttaa ttggttcctt tggctatcaa
     2161 aaagcagaaa gctgcctagt gtccacaatg tttgacattt ccaatggata aaaatgtctg
     2221 gcatacgaat ttttttcgct gggcctggcc cttgcacatc tacgacaaat gcctctgttg
     2281 ctcctttgtt aatcgcaata tcaataggta ttttgttgcg atacccaccg tctgcatatt
     2341 tattttttcc gatctttcga taagccatag cgggataaaa tgaagcagag gcgagtatcc
     2401 aatctggtat ttcttctgtt tttgtctgtt ggatatcagt cactacttcc gctagttctg
     2461 gcagtttagt agacaccgta tataaacgta ttttgggatt atgtttgagt aaggacaaat
     2521 ccaaattgtc tttgaccatc ttttccaatg gagcagaaga aaccccgcct tcaattagtg
     2581 ctgttttcgt catttggcgt ctttctcgat agaagcgttc acgaaggtct tcaactgcag
     2641 ccatttctgg taacgcaagc acttgtcttg tcgacagctt tttccataaa ttcacagctt
     2701 ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag gtacctgtga
     2761 taatctcaaa gttgatatca tgttccttca gcgcctgcca cacaccaatc tgataagcac
     2821 cgtgcgctcc tcctccacct aaaacaagtg ctgtatgata gaccagcttt ttatttaatt
     2881 gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa ccattcttct gatagaggag
     2941 attgaaataa aaaacaacag ttttctttaa taaaaaaacg agcgcaagct tccatatacc
     3001 gaaaaaattt tttccattca aaagtttcac cttcaatcaa cagattatta aaaataacat
     3061 ctcctctact tttagcaata gtaaaataga cggtatattt tttcgatact gctttaaaag
     3121 cacattgctt ttttgcagaa cgccaaaaag cgtctctact ttcttgatga ctttgaaaaa
     3181 atggaagggg ttgttttgct tgctggatag gcgaatacag cgacattttc tgtgaaaagt
     3241 aaactttttt tatctccatc gcgctctcct ttttcttcaa gtataccagt acgtcataaa
     3301 aaggtcatga gtctcgtatt cgactttgta gattccataa gaaaacaatt cataaaacct
     3361 cctttaaata aaaaaataca aaaatcacaa aaattaattg aaaatgagag tgttttcaat
     3421 gaaaacgtga ttttgtaatg gaattttaaa ataaaagaaa caagcttttt taatgcaaat
     3481 gttgtaaaat aaaagagatt aagaggaaat aagaggagga acatgatgac tgagtcagtt
     3541 tatgtacata ttgataccac aagtaatgct gttttaacaa aagggctgac tgctactgac
     3601 tttgcaaaca gtatcgtgca ttttcctcaa aacttgctct tgcttgatcc atctgcttct
     3661 gctggagaat atgaatccca tacagggctg aaagtaatcc gtggtacaga aaatattcag
     3721 cgtttctttt cctcttctcg taacaggcgt ggattcgatg aattgaagtg gatcgacttt
     3781 actgatttaa cgatgctgaa agaattgaca cctttagaaa tttcagaatt attatatttt
     3841 ggtcatatga aaacacatct tcattcgccg tttttttata aactacagaa taattttgta
     3901 tacttcgatc ttaatgatca gctgaatcgg atttattatc gctatttaga tgaattttat
     3961 aggatttttg ctagtaaatt aagttcgatc ttgtcagata agatcaatgt aaaaaaatct
     4021 tttttcaaaa aagaaacacc tgttgaaaaa atcagtgtgg aattattgaa agaaatgcgt
     4081 aatttgatgc aggaagggat cattttttct tttgatcaag ttggtttgat cgatggtaaa
     4141 tatcgtatcc caatctatgt gattgaagat tatatttgga aattaaaagg cacccggtat
     4201 cgagaagagg aaatcatcgc tactttaatc tactctgtca ccgatcgaca ctggcaattg
     4261 gtagaagatg ccgatctttc ttatctgcca ttgaagtaga tctatttctt atcaaaaaat
     4321 aaaaaggaaa caagaaacta ggacatgatt ctgtctcaag tttcttgctt cttttttatt
     4381 tacagctcct gtcgtttatc tggcacaaaa atcgaaggag tcgtttgttg gatccctaat
     4441 aaaacgatga tcgttacaat agctgtactc aacccgctgg caccattcat tacgaaagaa
     4501 aagagccaag gattcatccc ccatagtgca tacgctcccc agaaaaccac tcctgcaata
     4561 aaatgccaaa aatatctgga aagtgcgcca atcaatgcac caaacacgat gctttttcta
     4621 atttgtttcg tattatcgtc tacatagcct ttttggacat ttgaagccat gagccctgct
     4681 gcgcctgcaa aagtataggc aatcgggtac tcaatcaaca cttgaacgac acttaaataa
     4741 taaacttgtc ccaacggaaa atgtaggatg ccccaaatga aacctgccag catccctgcc
     4801 tttgtccctc ttcttaacgc aaaaagagtc aatggaatct gccctaatga aatagaaaaa
     4861 ctgctgccga tctggatcgg aatcaacgac aacaccatcg ctaacgctgc aacaatcgtt
     4921 ccttctaccc aaactctatt ttttcccata aaaaaacttc ctcctttgaa taaaaaagtc
     4981 acaaaggagg aagcagcttt cgaaaatagt caaacagctg tttattcaca attcctacgc
     5041 tcgcataacc gatacaggta cgaagggttt agaaatagat tcaatctcag cccaattgga
     5101 ctcccctttg tgagtttatt tattatttat tttttgtttc aaacaatgga ctaactggtt
     5161 tgttttcatg gatacgtttg attgcatctc ccattagtcc gccaacactt acttcatcga
     5221 ttttgtcgat tttacgatct tctggaagat agatcgagtc tgtaacaact agacgctcga
     5281 tagctgaatc ttctattctt tgtaaagcag ggccggataa tactggatgt gtacatgaag
     5341 catacacact agttgcacca gcttctttca aagcattggc agccaatgtg atcgtacctg
     5401 ctgtatcgat catatcatcg atcagtacac aagttttgcc tttgacttgt ccaatgatat
     5461 tcattacttc tgcaacattt gcttttggac ggcgtttgtc tatgatcgca atcggagatt
     5521 tcaaaaattc cgctaattta cgtgcccgtg tgacaccacc atggtctggt gaaacaacga
     5581 caacatcatc gcctttgatt cctttttcta agaaataatt ggcaataagt ggcgcaccca
     5641 tcaaatgatc gactggaata tcaaagaaac cttggatttg aactgcatga aggtccaaag
     5701 tcagcattct tgttgcacca gctttttgaa tcatgtttgc tactaatttc gctgtgattg
     5761 gttcccgtgc acgtgcttta cggtcttgac gcgcatagcc ataataaggc atgactacgt
     5821 tgattgtttt tgcacttgct cgtttcagtg cgtcaatcat gatcagcaac tccatcaagt
     5881 tatcattgac tgggctgctc gttgattgaa taacatagac atgcgatcca cgaatacttt
     5941 cttcaatgtt tacttgaatt tctccatcac taaattgagt aacagatgat tttcctaact
     6001 cgacgccgac tgctgctgca attttctctg ctaatgggcg attggaattt aacgcaaaaa
     6061 tttttaatct tgggtcaaag taatgttttg acatggggac ctccactttc tttttcacaa
     6121 ctctagaatt ctacctaata aatagtagtc ataattttta aataaatcaa gtgattttgc
     6181 aaaagtctta gtttagataa gggagttttt ttgcatatcc ttctttattg acttgtcttg
     6241 ctctcgcaat tgccagcgca tattctggaa tattgtctgt aattgttgac ccggcagcaa
     6301 tcgaactgtt tttagctacc tcgacaggtc cgatgatatt cgtgctagaa ccaataaagc
     6361 tgtggtcgcc gacagtcgta tgatgtttgt tctttccatc atagttgacg aagacaacac
     6421 cacatccgac attgatttct tctcccagcg tagcatcacc aacataagtc aagtgaccga
     6481 ctttagttcc tttgccgatt tgagcatttt tcacttccac aaagtttccg atatggacgt
     6541 tttcgccaat ttcagctttt ggtcgtaaat gtgcataagg tcccacatct gcatgtttct
     6601 tgacatggct gctttcaatg actgagtttt caatgacgac gtgatcctca atcctactgt
     6661 ctacgatttt tgaatgtgac ccgatgacac aatcagaacc aatgactgta tttccttgga
     6721 tttgtacacc tgcttcgatc aatgtgtctg gaccgatttc tacgcctgca tcgatgtatg
     6781 tcgttgctga atcgacaaag cttacgccat tgaccatatg catctggtta attcgctttc
     6841 tcatgatctc atttgcttta gctaacgcga tccgatcatt gactcccatt gattcttcaa
     6901 aatcatccgt ttgataagca gcaactgtat ggccttcttc ttttaagatt tcgatgatat
     6961 ctgttagata gtattcacct tgagcattgt ttgttccaac tttgcttaac gcatcgaaca
     7021 aagcttcgtt gtcaaaacag taagttcctg tattgatttc ttgtacaaga gcttcttctg
     7081 gtgttgcatc tttttgttcc acgatttttt ctacgatccc aatatggtca cggatgattc
     7141 gtccatatcc tgttgggttt tctgcttgtg ccgtcaagat cgttgcactt gcattttttc
     7201 cttggtgata ttcaaaaaga ttgttcagcg tttcagtagt caataatggt gtatcgccac
     7261 tgataactaa cgttgttcct ttttttcctt ccaagaaaga agcagcttgc aaaacagcat
     7321 gtcctgttcc caattgttct gcttgtaacg catatttact gcgttctcct agttgtgctt
     7381 taacttgttc tgctccgtgt ccaacgatcg taatcacttc atctggtttc gtttcactga
     7441 cccgattaat gatatgttct accataggtt taccagaaac gggatgtaaa actttatata
     7501 attttgactt catgcgggta cctttccctg ccgccaaaat aattgcataa cgtgcgtcca
     7561 actgcgtcac tcctaaatat agtttgctga tttcagttta tcccagtata cccatttttt
     7621 caacaaaaca agtgattttc ttttatccca gcgttttctg gataaaaaaa tagatagacc
     7681 ataacgggcc tatctatttg gtaaccggtg ctctcctgcc aactcctcgg tcacaagtca
     7741 cactactcat aaaacatgaa aagctgtttt ttgaaatcgt ttcttgtgac ttagagttaa
     7801 acggtaggct tacaacctct tcattaaacg tttttcaatc agctgacctt cggtattagc
     7861 tcaataaacg gcaaaatatg aggagcaatt tttccgttta ttgagctaat actcaggaca
     7921 ggacgctgat ttcacaacct ctagataaac ggtgttcaaa agccagtttc tcggtattaa
     7981 gccaaattta tgaaaaaatg tggaaagcca ttttcacaaa atttttctta ctactcgaaa
     8041 ctaagcagct ttttcacaac ctcttattct gaaaaataat ttcctggcac aaccgtaata
     8101 tttttcgttt gagtatctac atctttgaca taaagcagtg acgtataatc atcgatggcg
     8161 cgatgaccgt tgaattttga ttcggcaaat acagtgatgc caacaagttc tgattcgaat
     8221 tcttcaatca agctcttcat tccgttgact gttccgccgc ctttcatgaa atcatccact
     8281 acaaggacac gtgaaccacg tttcaaactt ctcttagaca gttccatctt ttcaattctt
     8341 tcagaagatc cagacacata gttgacactt actgttgatc cttctgttat ttttgagtcc
     8401 cggcgtacaa taacgaatgg cgcattcaga taataggaca cagcttgggc aataggtacg
     8461 ccttttgtgg ctacagtcat tacagcatcg attttttcac caaggtattt agaagcaatg
     8521 attcttccaa cttgacgcag cagttcaggt tctcctaaca aatcagagag ataaacatat
     8581 cctcctggaa gcagacggtc ttgttctgat agacgttctg ctagagattc aatatatttt
     8641 ttcgcctctt catatgaaat ttcagggatg aacaatacac cacctgcagc acccgggatt
     8701 gtttccaagg ttccataccc tcgttcttta aatgttttct tgatgattcc caaatcttca
     8761 ctgatagaag atttagcaga ttcataacgt tcggcaaagc ttgttaagga aatcaattca
     8821 tgcgggtgat tcaataaata ctgtgtcatg tcaactagac gttcactgcg acgtactttc
     8881 acctattcca actcctttta agaaatttta tcgttttaca ttatataagt ttttcttcaa
     8941 aaattcgagc attttatgaa aaaataagaa aatagttcgg tatttattaa aataaaaaga
     9001 agcctataaa aaatttttcg tttttataag gcttcttttc tttataattt agttattttt
     9061 tcttctgaag gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa
     9121 gactaatgtg attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga
     9181 cagcatccct agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc
     9241 taatcgcata ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc
     9301 aatcgggatc atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa
     9361 atgaacgggt agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg
     9421 ccgtttgaat aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac
     9481 ttgctcccat gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga
     9541 attccctccg ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat
     9601 ggcaatggag atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc
     9661 tgctaataca acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa
     9721 cgctacccct gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat
     9781 cactaaaaac acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc
     9841 tcttctcatg aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg
     9901 atctgtctgt ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat
     9961 ttcccatgga catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca
    10021 tccatacctg ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc
    10081 gctaaactga ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata
    10141 tcccacatcc ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga
    10201 cgcttgaacc agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta
    10261 ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt
    10321 ccttcttgat ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac
    10381 gatgctttca ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca
    10441 cccgcatcta catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc
    10501 aaatcagata tttcgatata acgcacctta caacctccat tctaaaactt aattgatact
    10561 ttcttttaaa gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat
    10621 ttgttcatta gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt
    10681 cgacaatgtc tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt
    10741 gtttttcttc acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg
    10801 tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc
    10861 agcatgctga gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg
    10921 atccagtgct tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt
    10981 atctggatat ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac
    11041 cggatcgagc caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc
    11101 ttcatgttcg tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat
    11161 caaggtctgt ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga
    11221 actattatac acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc
    11281 gaaatcatgc ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac
    11341 gatctctttt gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt
    11401 tttgtctgct tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac
    11461 cgtagctgtc aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt
    11521 ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc
    11581 atcaatttct gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg
    11641 ctcatatcta gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca
    11701 gtttttcatc acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt
    11761 cctcacaaaa accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca
    11821 aggcaaaaac ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca
    11881 tacgctcttt gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt
    11941 ttcccatttt tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt
    12001 ggatgtcttg atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga
    12061 cactcattct tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga
    12121 tttcttcccc tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg
    12181 taccgacttc caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt
    12241 ggttgatccc tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta
    12301 ctggaatatt cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta
    12361 gcaataaagc agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg
    12421 tttctacaat gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta
    12481 cgctcgacat caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca
    12541 gtcctaaatt tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa
    12601 aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct
    12661 agtggttgat tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa
    12721 caagttctag tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc
    12781 ctttttcttt tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt
    12841 tcctataagc aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag
    12901 cagacaggaa ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt
    12961 gaaagaaaga aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt
    13021 ccgagtagcc cattttctcg tatacaataa acagattggc taacagatag tcagctaatt
    13081 cctcagattc tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg
    13141 gctgagcggt gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag
    13201 ataatacata tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa
    13261 gccatttttg tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc
    13321 aagtaaaatg gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag
    13381 acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac
    13441 ccaattcatg aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc
    13501 ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc
    13561 caactggatc tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt
    13621 gatcttggtc gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc
    13681 ttgtagctgt gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac
    13741 tgccaagctt cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg
    13801 agatgcccaa accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat
    13861 gatttcctgt tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa
    13921 cgataaacaa aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga
    13981 attttgttcg ataaaattct tttctggata accacacagc taacagaatc aagacatata
    14041 ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta
    14101 aagcaatcgt aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga
    14161 gtaataaaaa gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca
    14221 ataatacttg aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca
    14281 tcatgatccc cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa
    14341 acagtcgcgg aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca
    14401 atagaagtcc cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa
    14461 ctactgctac atcttgccga acaggcaatt gactcattcc taagatcatc aaaacgtcaa
    14521 aagtccccat tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca
    14581 taggatagat cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata
    14641 ccgcaagggc tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg
    14701 gataaaactc gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg
    14761 ctaaaaaact accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa
    14821 taaaaaagac atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata
    14881 gtgcgacttt tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac
    14941 tagcccgcag acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg
    15001 ttacccacgc agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta
    15061 agactctgat cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca
    15121 gaatcatgag caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc
    15181 aactcatgcc attagcaata tttgcgactt gatttgccac aaagactaac acggagccga
    15241 aaaaaatcag ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt
    15301 tatttttcac attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc
    15361 ttatttattt taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa
    15421 agatatccta atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat
    15481 atggcacaag ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg
    15541 ttcgtttcca gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat
    15601 gcatgcaaaa gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa
    15661 ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc
    15721 atttctattg cttcaggaaa atcattaaca gatttagaaa cagcgcttga agatcctcag
    15781 gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg
    15841 atttgcaaaa atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa
    15901 gcaatcggca gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct
    15961 ggcagctcac ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg
    16021 aatggtttgt ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt
    16081 caaaaattcc tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct
    16141 ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc
    16201 atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga
    16261 tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt
    16321 cttttgtatt ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac
    16381 tttgatgtgt ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa
    16441 acgaacagcg tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc
    16501 agcttgaact gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact
    16561 tcttaaacga cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga
    16621 gagcgcatct gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg
    16681 atgagaagcg atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc
    16741 accgatctca acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag
    16801 caacccggca cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc
    16861 taattttgca acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg
    16921 cagacgtccg atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc
    16981 tgcctcttcc ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat
    17041 ttcttcgata cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg
    17101 tgcgatttct cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc
    17161 gatgattaaa tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc
    17221 aatgatacga cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga
    17281 aacttgatct gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc
    17341 tgcttcttct ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag
    17401 ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat
    17461 tttttctagt tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc
    17521 aattaattgc tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt
    17581 ttctaacgag tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg
    17641 agattttaat tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg
    17701 attttcttcc ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc
    17761 actatcgatg attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga
    17821 ctttgcgacc ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat
    17881 gttgaatacc ataaaatcca cctccatact atctttttca tttttatcat ctatacagct
    17941 tctatgataa attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa
    18001 catgcacaac tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa
    18061 acggctttct acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat
    18121 aggtaaacct ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata
    18181 tttttatttt atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa
    18241 aaaacggcag gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat
    18301 ttttattctt ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact
    18361 tcttcaccaa taccataagc tgctctaact agagcagaaa cttctgccat catttcagga
    18421 tgattagcca tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa
    18481 gaataccaag caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct
    18541 ccttcttgtg agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt
    18601 gctactttgt tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt
    18661 ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt
    18721 cctccaggag tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg
    18781 atgaaaatag cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga
    18841 gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct
    18901 cgtggaacta aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact
    18961 aaagcatcag cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca
    19021 tcgatattca cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg
    19081 aaagcggccg ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt
    19141 ttacctgaac tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca
    19201 cctaaagcga catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt
    19261 ttttcgccca atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca
    19321 gcatctaagg ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat
    19381 cagagcaaca tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac
    19441 cgaacaaata ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct
    19501 tgcataaccg cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa
    19561 accacgccgt ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac
    19621 gtgtccggtc cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt
    19681 gcttgaatgg ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc
    19741 tccggatcaa tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct
    19801 ggaaatactt cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc
    19861 aaactttccg ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt
    19921 gctagcgaat tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt
    19981 tcttctaatg ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt
    20041 cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca
    20101 atcagatctt ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact
    20161 ttagaaatta gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc
    20221 acaaacattg gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct
    20281 gtttgataaa aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg
    20341 ataatctggg actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat
    20401 gccaataatt ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca
    20461 gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt
    20521 tcacttcttg tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca
    20581 actgtttgat aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca
    20641 ttcgtattca cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc
    20701 attacttccc gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag
    20761 agggcaagga gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc
    20821 tcctgccaaa acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg
    20881 aaattatccc ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata
    20941 cttacattga tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga
    21001 tagtaaagat cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga
    21061 atgggatatt attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt
    21121 ttcccggcca agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg
    21181 tgacggctaa ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt
    21241 caaccaacat gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact
    21301 tgccaaaatt agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga
    21361 tactagctaa agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc
    21421 ctacgttaaa ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca
    21481 tacaaattct aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc
    21541 ctattctacg tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt
    21601 tattcaaagg agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga
    21661 cacagatttg tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat
    21721 ttatacgatc attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt
    21781 tcccctggat taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca
    21841 ccaatcgtga tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt
    21901 gctgccagtg tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga
    21961 ttgacagcag taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg
    22021 gcactgccag aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt
    22081 gttgattcta ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc
    22141 tcgactgatc cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga
    22201 cgatcttgcc aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat
    22261 aaaatgacag gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct
    22321 tttctagaag tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg
    22381 cttttcccat caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat
    22441 tgccgaataa atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg
    22501 attgcttcca aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt
    22561 tttttattca ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca
    22621 tcttctccag tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt
    22681 tgggtgctgt gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct
    22741 gccaactcct cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact
    22801 tgttccttgt gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca
    22861 atcagctgtt cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt
    22921 atgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt
    22981 caaaagcttg catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt
    23041 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg
    23101 tgttccagaa gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat
    23161 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta
    23221 cttcgtttga ttttatttta atataagttg attaaaagag agcatgattt gttttatttt
    23281 ctcactaatt tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc
    23341 tactacaagt ctaaaacgaa atttaagact tttcctcata aaatactggt ttattttggt
    23401 ctcatgtaaa actcgctgaa ggcctcttca cttataaatg cttccccagc tgccagtacg
    23461 tctttcattt ggatcgaatc gatgatttca ggaagatcaa ataaagttcg atcgccaaat
    23521 aaactttgcg taaattgatt ggcaatatat tcgatcgaat ttaatgattg gaaatattgt
    23581 ccaagcattt tcttcttcag caaatcgaga tttgtttctg acacttccgg atcatcagcg
    23641 aatccaagaa tgatttcttt gactttttct gctgctttct ctggttcgtc cgtatctccg
    23701 ctgaagtccg caaagtgaaa ttcacgatcc aagctgaatt caaaaccaaa gctgtcatcg
    23761 ataattcctt gattgtacat cgctagatag tttcgagaag tattgcctaa aatcatttgg
    23821 aacaacagat tgattgctgt tttatagcgt aacagttctg ttccttcttg cggcaatgtg
    23881 tctaatcctt taataccaag tacaaattta tctcgtgtaa tggctgcttc caatgcactt
    23941 tgtttgatga tttcttttgt gttttcaggg aaataacgta caatttcttg ctttggaggg
    24001 aaattttttg cttcttggtt ttcccgaata agtttcatca atttctcagg ctccatctta
    24061 ccaactacaa ataaaaccat attgcttggc tgataaaacg tccgatagca cgtatacaag
    24121 tcttgagctg tgattttgtc gatactttca accgtgcccg caatatcgat atgcaatggg
    24181 tgtgtaggat acaagttatt tagtatgcca aaaaacatcc gccagttagg gtcgtcttca
    24241 tacatttgga tttcctgacc gatgattcct ttttccttgt ttacagtttc ttctgtgaag
    24301 taaggtgctt gtacaaaatc gatcagagtc gtcagattct tttctacctg atccgtcgta
    24361 gaaaacagat agctggtttt cgtaaaactt gtgaaagcat tggcggaagc tccttgtttc
    24421 ccaaataatt gaaagacatc accatcttct ttttcaaaca acttatgttc taaaaaatgg
    24481 gcaattccat ctggaacttt caccttttct ttttcaccat agggaataaa ttcgttatcg
    24541 atcgaaccat aattcgtact gaacaaacca tatgtcttgt gatagtcatt tttaggcaac
    24601 aaatacacgg tcaaaccgtt tggcagtact tcatgataaa gtgtttcatt gatttgctca
    24661 tattctgttt tattcatttg catttcctcc tgctaaaaag aagattgcct gcaattcgat
    24721 ttgctcagct acttgttgta tctctttgat cgttacgctc tccatacgtt tcaaccattc
    24781 ttcatcagat aattttgttt ccggcagcca gctgtccaaa aaagaagctt cgattgccgc
    24841 ttgcggagag tctagagaaa gcagatattg gtttctcagc attgcttttg tctgagacag
    24901 ttccaactct gttatttcac catttcgcaa actttctaat tgctcgtgaa tcagatgaag
    24961 tacttgattt cggttctttt catcgatacc ggtttggaca ctcatgaatc ctcggaacgt
    25021 atccacgcta ctagaggcat aataagctag actttctttc tctctgacat tcatgaaaag
    25081 tttagagtga ggaaaaccgc caaataaacc gttaaagacc attagcgcaa aacgttctgg
    25141 ttcatcgtaa tacacatttg tctgataagc taggttcagc tttgcttgaa cgattggctc
    25201 acgtacttgt cgttccttca cgatattcac ttgaggttgg gtataaaaca gatctggata
    25261 aactgtttcc cgcgactcaa atggtaattg cccaactgct tcagctgctt tgtccggatc
    25321 aacatcgccg acaacaaaaa tgtcgatttg atcatttgcc atcatttctt gatagtagga
    25381 cgctagcgaa ctagcagtga tcttgtccaa atcttcgact acgcccaacc ctgggatctt
    25441 ttgttccggg ctgttttcaa aataaagttc ttgcaaggca taggaagcaa aagtttgttt
    25501 atcttccttc aaactttcca aatatagacg cagattgttc ttttccaagt caaacgtcaa
    25561 ctgatcaaac tgatgatttt taatatttgg ataaaataaa acctctttta aaaaatctac
    25621 cgcttgagaa aaaaggtttg gatcattgac atattcacca ttcacaaaac tgatccctgc
    25681 gtttagccaa tgtaaatttc ctttttttct aactgataat ccaaagcttg cgccataaag
    25741 ctctgcaagt tgcgcactta actttgtctg atccggataa ttcaaactat ttgtttccaa
    25801 catgctgctg agaagtgaac gtttcgtgat gacttcttgt tgcagacgcg cagtaaaacg
    25861 gataaaaatc cggatcgttt tgtattgttt tgttggtaag acatgaagat tcacgccttc
    25921 tgccaattga tacaccatat ttatatgctc cttttcacag ttgattgccc gcttactctt
    25981 ttaatgggtc aacctgcctt ttttacttat tcctctgctt gaaatttata agttcaggca
    26041 attcgccgtt ttttctaaat gatgttacac tttatagtat agcatagatg ttttttatca
    26101 aaagaaacag acggctaaaa gcgtatattg tttttttatt ttttattttt cgatatacta
    26161 aagacaaata aaagaaggga gggtcattca tgatcaaaga attcaaagag ttcatcatgc
    26221 gtggagatgt cttggatctt gctgtcggcg ttgttattgg tagtgcgttt acaagcatcg
    26281 taaaccaagt ggtgcaaggc ttgatcacac cactaatagg ttggtttgtc gcaatgatca
    26341 caggtacttc tgatttagaa ggagcacttt caattcttga ctggtcgccg acaaaaggcg
    26401 tcacatttgc gtttggtaac gttattagtg ctatcattac atttctgatc actggttttg
    26461 tcttattctt agttgtcaaa gcggcaaacc gtgcgaagaa tttacgctcc aaagaagagc
    26521 aagtggaagt ggaagaaact cctactgcag aagattatct tagtgacata cgcgatcttc
    26581 ttgccaaaca agtggcagaa gacaatacac atccagtaga gcaaacaaat ctttccgata
    26641 cttctaaata ataaagaatc taaaaaaaag aaagccgatt ttcagtgtcg gctttctttt
    26701 tttagattct taacttgcta cttgttcctt tttcatgtcg atatgtggaa tatcatcttc
    26761 caaatacaca tctgagattg ccttgaatcc aaacgactca taaaaagctt gtaggtattc
    26821 ttgtgcgccg atcacgattg gtttttctgg aaaatttttc tggatcatgt taatcgtttc
    26881 ttgaacaatc tttcttccta aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc
    26941 aaaatggata ctctccgctt cttcatatac tcgcgtgtag gcaaggatct tcccatcagt
    27001 atcttgaaaa aacgtatgcc aagcttgtcc atcaatgtca tcaacttctt gataaggaca
    27061 ctgttgttcc acaacaaaaa ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt
    27121 tgacaattct tcaaatttct ttacctgata ttccactaag caaacgcccc ctgctttttt
    27181 attcttagca taccgattcg cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg
    27241 tttgcttttt aaactgcttc agttaaaaat tcgatctcaa ctgtccgagt aagtacatct
    27301 gaatagctgt aagatactcg ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat
    27361 actgaaggat aggtttctgt taaaacgccg cggcgttctg tttgacgctt tcttcctgtc
    27421 tgagcaacca acatgattgg gctgccgata cgaccttcta aatctttctt gattgaagct
    27481 aaagttgttg gcatacagtt cacctctact atcaactata ccacatattt ttaaaatttt
    27541 caagtttacc ataaaaaaaa agaaatgcaa taaaaataaa taagaagctc attaagattt
    27601 ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc
    27661 cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat
    27721 caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc
    27781 aattttcgat tgcttctttt aataaaagat gctgaatcgc taaaggttct tgcaatgtga
    27841 tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt
    27901 tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta
    27961 taatgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg
    28021 cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat
    28081 aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg
    28141 cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc
    28201 ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata
    28261 tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct
    28321 tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct
    28381 attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct
    28441 ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc
    28501 aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct
    28561 ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt
    28621 tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga
    28681 tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc
    28741 ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac
    28801 tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt
    28861 aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat
    28921 cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc
    28981 catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg
    29041 agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc
    29101 ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc
    29161 acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct
    29221 tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc
    29281 agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg
    29341 ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt
    29401 tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag
    29461 agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa
    29521 ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt
    29581 ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt
    29641 gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc
    29701 catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc
    29761 gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc
    29821 tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat
    29881 caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg
    29941 ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc
    30001 aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat
    30061 cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt
    30121 tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt
    30181 tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat
    30241 tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga
    30301 taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa
    30361 tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc
    30421 gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta
    30481 ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc
    30541 ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg
    30601 atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg
    30661 ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc tgttttcgct
    30721 tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg
    30781 atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg
    30841 ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat
    30901 aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct
    30961 ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg
    31021 gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga
    31081 ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggctcg
    31141 acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt
    31201 gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc
    31261 gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca
    31321 atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac
    31381 ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg
    31441 tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg
    31501 gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga
    31561 ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg
    31621 ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta
    31681 cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca
    31741 ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag
    31801 ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata
    31861 aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct
    31921 cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc
    31981 aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa
    32041 gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac
    32101 ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac
    32161 tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag
    32221 gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca
    32281 gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg
    32341 atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg
    32401 atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa
    32461 cagctttgat ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg
    32521 ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt
    32581 cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat
    32641 agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat
    32701 ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg
    32761 catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga
    32821 aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt
    32881 cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg
    32941 catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac
    33001 gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg
    33061 gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt
    33121 catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat
    33181 tataagttgg cataccatcg cgtttttgta tgacaaagtc gccaccgata ttatcggatt
    33241 cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac
    33301 ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca
    33361 agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt
    33421 ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct
    33481 gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc
    33541 caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc
    33601 ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt
    33661 ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat
    33721 gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct
    33781 tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat
    33841 catttattta aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa
    33901 ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt
    33961 ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc
    34021 atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg
    34081 taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt
    34141 tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact
    34201 ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag
    34261 actttattca agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg
    34321 atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat
    34381 ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt
    34441 ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc
    34501 atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc
    34561 acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt
    34621 tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact
    34681 ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc
    34741 atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc
    34801 gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa
    34861 gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg
    34921 gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta
    34981 ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa
    35041 atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt
    35101 tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc
    35161 aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt
    35221 ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata
    35281 tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc
    35341 tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct
    35401 ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc
    35461 aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct
    35521 gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc
    35581 aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg
    35641 cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt
    35701 tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga
    35761 aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt
    35821 cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca
    35881 tttgttttag cgattttgag tagttctgca gtggtttctc ttacttggct gacacttcct
    35941 gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca
    36001 ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa
    36061 aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct
    36121 tcgccggata catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac
    36181 agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc
    36241 acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt
    36301 ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga
    36361 gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa
    36421 tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt
    36481 acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc
    36541 aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag
    36601 cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct
    36661 cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc
    36721 cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca
    36781 ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc
    36841 ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg
    36901 atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc
    36961 agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg
    37021 tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc
    37081 tttttctcac cggttttcct ccctaaataa actactccta ttctaacata tccgaggctg
    37141 taaaagactt tctttacaaa ttcttcaaga aattctgcta tcttaaagta aaccattaat
    37201 tcgttctttt tccaaacgac tgcaagttgt acaaaaaaac tattttttac atgactttac
    37261 tcgtcaaaac aagtagaata gaacgaaatt aatgagtgga tatttgattg aggtgtcaca
    37321 tgcgtaaaga aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca agtacattga
    37381 tttatcccaa tggaaatatc aatcttgcgg caatcgatca gttagctttt gtcctttctg
    37441 atcttagaaa tcggggaaag gaagtgatct tagtctcatc aggagctgta ggcgttggta
    37501 tgcataaatt acatttgtca gaacgtccga ctttgattcc tgaacagcaa gctgcggcgg
    37561 ctgttggtca agccgaactg atgaatatct ataatcaaag attcagtgta tataatcaac
    37621 agacggcaca gatcctcgtg acaagagacg tggtagatta tcctgaaagt cgtaaaaatg
    37681 tgaggaatac attggaacag cttttgatta tggacacgat ccctatcgtg aacgaaaacg
    37741 atactgtagc agtggatgaa ttagatcatc tgacaaaatt tggcgataat gatcagctgt
    37801 cagccatcat ggcaaaactt gtcgcggcag accttttgat cgtcctttct gatatcgacg
    37861 ggttttattc agataatccg actacaaatc ccgaggctca gatgtatcgc tatatcgata
    37921 aaatcgatga aaagattctg gcacaagcag gtggtgctgg tagcacattt ggaacaggcg
    37981 gtatgcagag taaattaaaa gccgcttcta ggatatttga agcaaacagc gcaatgattt
    38041 tagcaaatgg aaaaaatccg gcaattattt ttgatattct tgcaggaaaa gaagtaggta
    38101 ctttatttaa ggaggacttg aaatgactga cttgatgcaa ttaggacaac aggcaaaaga
    38161 tagcgcgcaa caactagcac ttatgcctac aaaccgcaaa aatgagctac ttgttcaaat
    38221 ggcacaaacc atcaaaaaga atcaacaagc gatcattgaa gcaaatcata aagacttaga
    38281 aaaagcagtc gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc tgacacctga
    38341 gcgaatcaat gccatggcta cagagatcga aaaaattgct tcgttagacg atcctattgg
    38401 aaaagtagat gagatgtgga cgaacaccga cggattgaga atcggcaaaa agcgcgtgcc
    38461 actaggcgtg accggcatca tttacgaatc tcgtccaaat gtcacgacag atgcagctag
    38521 tctagcattc aaatcaggga atgccgttat ccttcgcggt ggcaaagaag cattcttctc
    38581 gaatcaatta ttagtccaat tattgcagca agtactggtc agtgctggcg aatctcctta
    38641 tgccatccag tttgtcgatg atacttctca tgaaactgca ggacagttga tgcgattgac
    38701 agaatactta gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac gagtcaaaga
    38761 acaggcaacg gtacctatca ttgaaacagg tacaggaaat aatcacgtat atatcgataa
    38821 agaagcacag ttatctatgg cagtgaacat catcgtcaat gcaaaagctt cccgtccatc
    38881 tgtctgtaac gcggcagaaa cattgctgat ccattctgag atcgcacctt ttttcttgcc
    38941 agctattgaa aaagaactgg tagaacacgg ggtctcttta cgtgcggatg ctcgtgcgtt
    39001 agaatatcta gagacggctg ctttagcaga agacacagat tgggatactg aatatctaga
    39061 ttatatcctt gctgtcaaag tggtcgattc tttggatgaa gcaattgcac atatcaatcg
    39121 gcataatact aaacattcag aaacgatcgt gacagatagt tatgcggcta gtcaacgttt
    39181 cttaaatgaa gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt ttacagacgg
    39241 atcggtattt ggttttggtg cagagattgg tatctctact caaaagttgc atgcccgtgg
    39301 tccaatgggg ttaaatgaat taacttccac aaaatatatc atttatggcg atggacaaat
    39361 ccgcgaataa tgtttcgtgt gaaacattat tcccgccttt tgcctttttt ctgtaaaggt
    39421 tctatccaac tagaaaggtg tcaatatgtt tgaaatttta atgatttttt ttatttacct
    39481 tatttctctg aatatcgctg cttttctggg agtcggtatt ttatcccttt tctttcaatt
    39541 caaaaaacga agcataggga gtcaacggga aaaatggtcg cagtattttg acaaaatcgg
    39601 gcaaaaaggg ctggttacac gcttgcacat tagttacatg gttgcattat gcttattagc
    39661 gacaatcaat tactattctt ttttcgatca ttcaatcgct tatacgatta cgctactgat
    39721 tgctgggatt tttcacttat cttataaata tcagctgaat aaaaaccact tgaatcggac
    39781 tttccgctaa aaaatatccg tacgataagt agagtgcctt gaagatcggc aaaaaactgc
    39841 cggacttttt agaggctgtg acaaagattt tgtcacagcc tctttttcca tataaacggc
    39901 gttcgcctac cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg aaaatccgtc
    39961 aaatgtttcg ccatcataat aacgaagcag ctcatccatg gacaagttca tcgttttttc
    40021 tttttcttct tccgctgatt cagccagtag ctgttcccga tacacctgat acataccagc
    40081 tattttttgc tgcatcgctt ttctagtttc accttccgca ttgattattg gcaattcttt
    40141 gatatagcca cgataaatca accgatcatc tgaaaattca atgggtaatt caacgagtgt
    40201 caacccgact tcctgaaaat attcttccag catctattat ccccccattc tttttcttaa
    40261 atgaatttta gcttacctac tgaaaatttt ccagtttcat tattttgaga aaaaaaggga
    40321 atgtgacaaa aatcgtgtca catccccttt ttccgaataa atggtgttct tctgccaact
    40381 cctcaatcat aagtcacaat attcaacaaa catgagaaac tgttttttga aattgttcct
    40441 tgtgattcag agttaaacga cagtctcaca acctcttggt aaacggcgtt caaaagcttg
    40501 catctgcggt aataagccca accaaacgaa aaatatgaga agctattttt gtttggctgt
    40561 tcttatgact tgatgcagga cagctttttc acaacctctg atttcttatt cttcttcatt
    40621 tgtagcaaaa taattacggt gataaatgat acaacataca ctgataagaa caatggcacc
    40681 tgcaaaataa aacgcatagc tttcaccaat atgttcacca atcacacctg caataaatgg
    40741 tgctaaagct ccaccgaaaa agcggacaaa actatagctg gacgaagcaa cgtttcgttg
    40801 cagacctggt atttccatag caatcgtcgt caacagtgta ttgataattc cttggaaaaa
    40861 tcctgctaac acaatgctga tcggtacaag gactggcata gaagttccag ctcctaataa
    40921 cagcaaacaa ataatgaata agacaaatgc tgctaaaatt gtccgataag tcgtaaactt
    40981 ccgctcaaga gccggtgcaa cgaaaatcga agcaatagcc agaagcacac cccagccaaa
    41041 aaatacaaaa ccgacttcta attcagaata gccaatcaat aaaaatggcg catacgcaag
    41101 taaagtaaag aatccgaaat tatataacaa tgcgattagt ccaactgaac gaagtttatg
    41161 attgcttaac gctttgacac cttcccaaag gcctactttt ctctttggtt tctcagtttc
    41221 aggtaaaagt accgctaggg ctataaaacc gcaaaacatc aaaaatgcta ccccaaaaaa
    41281 tggataacgc catgaaccac tgcccaagac cccaccgact agagggccaa cagccattcc
    41341 gcagccaagt gctgcttcat acatcatgat tgctttttct gtgttaccaa ctaaaatact
    41401 gacgatcgtt gctaaagcag tagagacaaa taaagcattc ccgacacccc agccggcacg
    41461 taacccaatc agcattccga tattcccaga taatccgcca agaccagcga atacaacgat
    41521 gataaacaat cctgtcatca atgttttttc aaaccgatcc gactagataa gaaacctgta
    41581 aatagcatca ccacaccagt gactaacatg taactagtaa ataacagggt cgtttcagct
    41641 ggcgtagcgt ttaactgtgc agcaatcgtt tttaagattg ggtctactag acccactccc
    41701 ataaaagcga tcatacaggt agctgctaca actagcgctg aacttttccc ctttgtttct
    41761 tcatttgttt gttcttgtat atctatttga ttctccaata tttccatccc tttctctcta
    41821 ttagcatcat acatgattta ttttacatgt aaatatgcac atgtaaaacg tggaaacttt
    41881 actgtgatat aataaagaaa ataagacgag aggtaggatt tttatgaata ctttagccta
    41941 tatattatta tgcgtgcttt tatccaaacc acgttctggg tatgaattga agcagctgat
    42001 cacaattttt tgggaagccc atcacagtca gatctataca acgcttgcca agttagacca
    42061 gcagggttat gtgaccgttt tggacaaaga cgagcactct caaaaaaaga tctaccactt
    42121 gactgatgaa ggacgtgctc ttgtagagga atggatcaaa gaggaaactc ccgctcctac
    42181 gcaaaaagat gaatttctag caaaaatcta tgctttttcg acgctcgata aaacaacagc
    42241 tactggactg ctattcacta gagaacaaca gctgaacaaa atcatgcaaa aaaatcaaaa
    42301 aaaattgaat gacctctcgc tagacaagaa acaagaattt ggacgttatg ttgtgatcca
    42361 gcgcagaatt atgctttgtc agcaggaact ccaatggtgt cagcaagtaa gagaacaaat
    42421 gcagcagttt tttgagtaag ggataaacag aacctttcta gaaatatcta ttgaagagca
    42481 aattatcttc aataaaagag caatacagtt ggaaaagaaa aagcgatccg aacgacaggc
    42541 caaaacctat cgttcggatc actatttttc tagaactgca ttcaagagac tatgacaaaa
    42601 agcatgccaa ggcctttttt caaataacag tgttccatca ttcattactt tgaattgctt
    42661 ttagcacact tcttgaaagc gggccaacga tgatcaactg caacggtaaa gcggcaatca
    42721 cattcatttt ccaagcattc atataagcag agaataattg atcaggtatt ccttgttcca
    42781 tgatcacacc gaataaagac atacatgtca ccattcctaa aaccatcaag catgaaatag
    42841 ttaagatcat ttggaccttg ctttctggat ttactggtag tttaaaggca atttttttcg
    42901 ccagcacacc gatgatgaag acatccaaaa tgaaagccac cacgaatcca ggcactagac
    42961 caatcaacaa acttgataaa tgaagatctt gatgcagcca taaattatac gcgctcatcc
    43021 ccaagaccat caaaaaacac atcattgttg taaaaattat tccttctttt ttatttgtag
    43081 gcaatctgta ccactccttt aaatttgtca cgaaaatcat cgtagcacat ttaaaaattt
    43141 ctcgtaagta ctttttttat tttctgccct tttatttcat aaacttcatc agccgtacgc
    43201 tcgacaaagt aagaatcatg agaagtaaac aaaatcgttc ccggatatat ttgcattagc
    43261 ttctctaaag cttcgatcgt tgccatatca ataaaattag tcggttcatc taacagcaac
    43321 acattacttg gcttagtaaa aagcaaagca atcgtcagac gggtcgcttc tcccccactt
    43381 aatgtacata acggtttcgt caaagtttcc tgagcaaacc ctaagtgatt cagcaaacta
    43441 cggacaagcg attctgaaaa ctctgtttgt ctcatgacaa aacgaatgat ggattcttca
    43501 gatgtcattt gataaccctt ttgctgatat acttgaaagc ttactttcgg agagagaagg
    43561 attccttctc cttgtttgcg gatatgttct aataaggttg tcttacctga accattttca
    43621 ccgacaatcg cgattttttt acctaaagaa aactgaaaat caccatttac cagtaatgtt
    43681 ctcccacttc tttccaattg gacattttgt cccatgatgg gatagcggct gtggagttca
    43741 agagattttg gtactggaaa acggatttgt ttcatctgct gcggcttggt tgtttctcct
    43801 attttttgga gtcttctctc taatgttttc gcattctttt ggatggcttt ttgtacactg
    43861 tctttttgtt tagaggaaga caaccgatcc ggtctgattt gttgcttttt ctttttactg
    43921 gacacttttt ccaacttttc cgcttgtttt ttcttttctt ggatcgattt ttccaatcgt
    43981 tttttctctt tcatgatcga ctctgcttct cgtagctgag tctttttctc caattccttt
    44041 tgagtgagat aggcactata attccccgaa aactctcgga tttctccgtc ttttacttcc
    44101 cagattttcg atgctagctc atctagaaaa tagcgatcat gactaacaaa aaccagcgta
    44161 ccataataat aacgaagctc ttcaatcagt cgatcaatac tttttctatc tagatgggtt
    44221 gttggctcgt ctagaagcat cccttgttca taagaagaaa gaagacgtat caactcgatc
    44281 tttcgttctt cccctccgct ccatttccgc tctgaagttt cttccagtct taactggaaa
    44341 tgactggcta attccaaatt taggtccttt gcttcagcga gataggttaa ttgaggcagg
    44401 tagttgaagg tgatctctgt ttggattttc ccatgatcgg gaaaaagttc accggctatt
    44461 agtttgagca aagtcgattt accgacacca ttttctccta tgatccctat acgatcttgc
    44521 tgatagacac gaagagaatc aatagatagt tctagctggt tgccaaagct gacttgtaga
    44581 tttgttatat ttactgctaa attttccata tgttttacac tcctatttca tgtaaaacaa
    44641 caattatcga tactaaaaaa gagcagaaaa atctgtttgc aaaaaaactg catcacatct
    44701 tttcctactc tgaacgaaat aactatgact aaatcaccaa atctgtcata gctttcacct
    44761 attctactgt cgttcgaaaa aatggacata ctccatccat gaaattgttg tttatacatg
    44821 tcttttgaat ttatttagtt gttattcaaa agttcgaaac gtaatttcat cgatgcagtc
    44881 atttttccga cctccttttt tattaggtta ccacacacga ttcaaaaaaa gcaatagcta
    44941 ctgaatagta actgaaaacc ttttattcga acgtagtgat cttttctggt gctaaacgaa
    45001 cagactcgta accttcttct accgcttttc ctattgataa aataataact ggaacataac
    45061 ggtctttatc caaaccaaat gcctctgcca actgatctgc ttcgaatcca ccaattggat
    45121 ttgtttcata gccatgatca cgcgcaacta acatgaattg catagccgct aagctagaat
    45181 cgactttgac tacatcgttc atttcttctc ttgaaaaact cttgtaataa ggaatgatcg
    45241 cagctaattg ttgatctctg acttcttttg gcatcttccc tgattcgtaa gcttggttat
    45301 agatttcttc gccatattcg taacattgca tatcgccaaa aatcatgacc attgcagaag
    45361 aagtatcatt ttgtctcgta ttgaaacgga tcaaaggacg caagatttct tttgcttcct
    45421 cgctttcagc gaccacaaag cgccatggtt gcatattgac agaagaaggt gcagtcgtcg
    45481 cttctttgat catttccagc atttcttcgt gtgggatttt gtatgtttca tcatatacgc
    45541 gaacggatct tctaccagtc ataattgttg aaaaatcatt tttttgttcc attattatta
    45601 acctctttcg tttctgttgt tatattgcaa agttgggtat tcaatttatc taaaagtgtt
    45661 agaaattgtt tcatttctac atcgctgaaa gccggggata gcacggaacc tgtatcttta
    45721 tggtccattt cacaatgctc gattttcttc tgggcttttt ctgttagcgc tacatacact
    45781 tcccggttgt tctgaggatt tctctgacgc gaaacatagc catttgcttc caataccttc
    45841 agatgacgag taactgctcc ttgatcaatc tgcaactttt cttgcaaact gctttgtagc
    45901 aatggatttt cttctttcag tctcatcatg atctcgtatc tagtaagact tataccgata
    45961 ttttcttcaa agatctggac gattttttga tcggctaatt tgatttgata taaaaggtga
    46021 ctaatctctt ctaaagacat aatttcctcc tttctaataa ttgactcgtc aacgattgac
    46081 ttgtcaataa tagaataaaa aaagaaaaaa gtcaaagaat cagctgtgta ataaaaaaaa
    46141 cgctctcaat agaaaagtat agagaaaaga aattttttgt agaatgaacg gaaaaaatga
    46201 taaagaaagc acaacgctaa aaccaagatt attgattctt atcaaactat agaagatagc
    46261 tcttctgcag tagaaaattt tacaccgcca aaaatttccg aaatcgcctt ttgcaagaat
    46321 cccgtcgaat attagaaatt ggatcagtat gcttaaacag taataaaaaa gttatgacaa
    46381 gatgttgtca caaccttttt tgagtaaacg gtgttcaaaa acttgcatct gcggtaataa
    46441 gttcaaccaa acaaaaaaca tgaaaatctg tttttgtttg gctgttctta ctacttgatg
    46501 cagggcagct ttttcactac ctctttttaa taaccataaa atcctattcc ttcatatctc
    46561 cagcccatcg gtgttagcca atctctttcc ttagcactca aggtatagtg atgggtacca
    46621 gttttttcat ttggattaaa tagtcgataa attggcttgg aaccaccaga ataaaaactt
    46681 agaccttcat aacgccaacc gatttttgtt aaagagttga tctcagattg tgccattgtg
    46741 taatgatggt ctccactgta aggattgtat aaacggtaga caggttgtcc gctgtttggt
    46801 gcttgccaag caatcccttc atattcccag cctacagttg gcagataatt tttttctccg
    46861 gcattcaatg tatataaatg ttctcctgta tgacggttat acagacgata catcggagaa
    46921 gttgaagttg gtgctgtatc atactgtgtc agattatagg tttcgattac attgttcaat
    46981 gtagaaccat aattaggcgc agtggcataa cgacctgtta gccaagccgt agcatctttg
    47041 taagagttcg tattgctttt ccatgcaccg gaatagtagt aaacgcctgg ctgaaaagaa
    47101 gtcgtcttca ataccgttac gttatcttgc aatgattctt tgtacgaagg atattttcta
    47161 aaagcggcat tcaccgtaat ccattgccca ttcacatatt ccgaagtagg catcgtaaca
    47221 gattggccat tatagcttcc tttaatccca aatagattgt aattaggggc agaagccaaa
    47281 gtactgttcc cccagccact ttcaacgatg gcttgagcaa tcatgactga tgcatataag
    47341 tcattggcac ttgccaaact ttgtgcagtt gaggcaatac tatcaatgaa cgcttgttga
    47401 gaattagcag atgagcgagc ataaaaagca tagccagtat agttttcgaa ttcagacaaa
    47461 tctgcttgat gggtatgtgt caatgtttgc ccatctgtca attggttcgt gatttcttct
    47521 gcattctctg gattgttctg agcttctgct gatgtactgt cttcggtttg tgtttgttct
    47581 gttgtttcag ttgttggttc ttcggttgaa attgtatttt ctgagacagt agctgactgc
    47641 aaagtactct ctgtatcgtt ttcaattcct gtttctgaag aactcgatgt ctgagttgcg
    47701 acagtttctg tcgattcttc agctagcact gttgtgttgg caactgctag atttcctaaa
    47761 agaataacgc taaataataa attctttgct ttcatctttt ttctcctttg aattatgaaa
    47821 cttttcctaa ataacagtgt aactaaaaaa gtaaaagcaa gtcaatgtcc atatttaaat
    47881 aacatttgtt tctttttgat aaatttgctt tttctacata aaaagacgta aatgaagaat
    47941 attcttctcc attcacgcct taaattgatg gtcgtttgaa taactattta acaagtaatt
    48001 ctctttggat attatccgtt atggattata cttcctgtgt cgtcggacgg ataatcatgt
    48061 tactgacaga catccggtct ggcgtttcta tcgcaaatgc tacagcagaa gctatatctt
    48121 cggaggtcaa tccccattct ttttgcgctt catgaagttc aagagcagcc tttttgtcgc
    48181 tgatggtttg atataattca gtttgaacag ctcctggaga gatgatcgta gatttgatgt
    48241 tattttgccg ttgctcttga cgtaatcctt ccatgattgc acggacagca aattttgttc
    48301 cgcaataaac ggcggaatca ggataaacaa catgtcccgc cacagaatca gttgaaatga
    48361 tatgcccaga tttttgtttt tccatgattg gaagtacggc ggaaattcca tttaacacac
    48421 ccatgatgtt gatatcaagc atattttgcc attcatcacg gtgaccttca actaatggag
    48481 cggttggcat gattcctgca ttattgtaca atacatcgat tcgaccgaac ttttccatcg
    48541 ctaaatcgat aactgcttgg acttgtgcaa aatctcttac atctgctgtt tgaatatata
    48601 gctcagcttc tggtaaagat tcttttattg cttttaggcg atcttctcgg cgtgcagcta
    48661 taactagttt agcccctttt tctgctaata gcttcgttgt tgcttcaccg attccgcttg
    48721 aagcgcccat gatgacaatc actttttctg ataaatcatt cattctattc tcctcctgtt
    48781 ttgaaaaatc tcttgcttat actcactatc tcttatttca tcttactgtt caaataatcc
    48841 gttcgacagg tttgacgatt ttggcaggga ttcctgcaac gatggtattg tctgggacat
    48901 ctttcgtaac agttgcattc gctgcaacaa tggcattctc gccaatcgtt acgcctggca
    48961 gaatagttgc tcctgctccg atccaagcat ttttcttgat gtggattggc tttactgaca
    49021 agcctcttcg ttcttttgga tcggttagat ggttcaccgt gatgaggttg acacgaggac
    49081 caatcaatac tgaatcttct aaacagatgc cacctaagtc aacgaacatc acttgacgat
    49141 tgataaagac atttttccct atactaatat gtttgccgaa atctgtataa aaaggcagca
    49201 gaacagtcac cgtatcatct actttgtcac taatgatatt ttctagccgt ttgcggatat
    49261 ctgctggttc atggtaccca gtattcagcg ctgctaaagg ctcttcgttt tcagcttgga
    49321 tctgatggat cacttcaaag agcggatccg ttactcgaat ctctttattg acgatttgtt
    49381 tttcgatgag gcttgtcatt ttgctccctc cttttatcct tactttataa cggacggctt
    49441 atcatgtcta atacttataa aacatactta actattcctt ttaactatac ttagtggtat
    49501 gcttttttaa aaacaggagg gaaaaaatgg atattcgtat actgacgtat tttttagcag
    49561 tagctagaga aaaaaatatc agccgagcag caaaatctct gcatatcacg caacctactc
    49621 tctcaaaaca actgaaagat ttagaagaag aacttggtgt gacacttttc actcggggct
    49681 cccgagagat acagttgacg gattctggtc gatatcttta ttcaaaagga aaagaaatct
    49741 tgtcgttggt agaaaaaacg gcgaacaatt taacaaatga cgcaatcatc tctggagaaa
    49801 tctacattgg cggaggcgaa actaaagcaa tctctttcat ttctgatagc cttcattcgt
    49861 tgatcaaggc gcatcctgat atccagtttc atttatatag cgggaatgca gatgatatca
    49921 tagacaaact ggatagcgga ttacttgatt ttggactcgt aatcgaaccg acaaacaaac
    49981 aaaaatacca gtcatttcga ctgccagccc aagatcgttg gggacttttg atacatcgaa
    50041 atcatccttt agcaaagcaa accgtcatcc atccgcagga actgaaaact gttcctttga
    50101 tcatttcccg gcaaacgtca gtggacagtc aactagctga atggctaggt ttcagcatag
    50161 atcagttatc gatcgtcgga acatataact tattgtacaa tgcttctttg atggtcgata
    50221 acgggacttt tggtgcatta gctctagatg ggatcatcaa tacttatggg acggaaaaaa
    50281 tattcatccc actcgatccg ccattacaag cttcactgaa tctcatttgg aaaaaagacc
    50341 agcctctttc tcctgctgct cgtaaatttt tagatgtcct aacggagaaa tacagttaag
    50401 tagagttttt ttccttcgct ttcagctttt taacaacgaa taagataagc aaaagatcca
    50461 acgattaaat aacataagtt tcttaattta tttcttcctt ttatttctga taattccagt
    50521 aaattactat aattataaaa aaagaattga caaaacataa ctgtctatat aaaattgatt
    50581 acgttaacaa taattcgttt catgtgacta gatcatacta ggcatgaaaa atctctgagg
    50641 aacatggttt ccctaggagg tttttcgtgt ctatttttgt ttggccgcaa tcaactggtc
    50701 tagcaaacgt gaaaaccaaa tcttcaaaaa gggtgcgcgc atgaaaatca aaaagatctt
    50761 taatcaaaat gcagtattgg tagatgacgg tggacaggaa aaagtagcta ttggaaaagg
    50821 gattggattt gacagaaaaa gaaatgattt gatttttgat cgtgatgtcg aacggatatt
    50881 tgtcatggaa ccagaaggtc aaatcaagtt gcaaaattta cttaatcaga ttgatgaacg
    50941 ctttttattt gcagcagaaa cgatcattga tcatgcggaa actgttttga tggaaaagtt
    51001 gaatgaacat gtattgatcg ctttgaccga ccacattgct ttttctgcgg agaacattaa
    51061 taacggtatc gtcatccgca acaaactttt aagagaaatc gaagtgcttt acagtgatga
    51121 attcagtatt gctcaatggg cagtagagta tctgacaaaa gagcttggga ttccatatac
    51181 ttatgacgaa gcaggatata tcgcaatcca tattcacagc ggacgaagcg gtcggaacaa
    51241 taaccatcgc agtatccgtg aagtgacgat tgtatctgac atcatccatt tagtggaatc
    51301 agaattggaa acagatatcc attcagaacc attttcactg aattattcaa gactggtgaa
    51361 tcatttacga ctgcttctac aacgaaccca tgcgcaacaa tatgctgttt tagacacgga
    51421 aatcgtagaa atggtcaaac gaaaataccc agaaagctat aagatttcta aaaaaatccg
    51481 tgtgttgctg accaaagaat accagctcgc gatcacgaaa gaagaactgg gttacttggc
    51541 catccatatc gagcgtttaa gaagcgcaat cgtacaaaca aatgttaaca atcatgagga
    51601 ggaaaaaaat tgaaagcata tctacaacga atgggacgtt cccttcaact tccagttgcg
    51661 gtcttacctg ctgctgcttt actagtaggg atcggaaact ggtgggcatc ttatagtaac
    51721 gacattgtcg ctcatttttt acaagctggc ggtaacgcag ttttaggtca attacctttg
    51781 ctgtttgccg ttgggttagc actagggatg tcagtggaca aatcaggtgc tgctgccttg
    51841 gcaggtttgg tcgcatttga agttccagta aatgttttaa aaactgattc agtagctact
    51901 ttattgaata tcaaaccaga atcagttgat ccatcttttg ctcagatcag taacgtattt
    51961 attggtatta ttgccggatt gattgcggca gctctttata atcgtttcca cgaagcaaaa
    52021 ttaccgatgg ctttatcttt ctttagcggc aagcgtctag tgccaatctt ggctgccttt
    52081 gtcatgttgc tgatcagtgc agtgctactg ctcgtatggc ctccggttta ctctgcttta
    52141 gtttcttttg ctaaattcat tttgagttta ggctggggtg gtgcaggtct ttatggcttc
    52201 ttcaaccgtt tactgatccc tacaggattg catcaagcaa tgaactccgt gttctggttt
    52261 gacgtagcag gaatcaatga tattggtaaa tttttggctt ctgaaggaac aaaaggcgta
    52321 acaggaatgt atcaagctgg atttttccca atcatgatgt tcgggcttcc agcaggagca
    52381 tatgctattt acagaaatgc acgtccagaa aacaaagcaa aaacagcttc cttgatgcta
    52441 gcagcagctt ttgcttcatt ctttactggt gtgacagaac cacttgaatt ttcatttatg
    52501 ttcgttgctt ggccattata tgtcttgcat gcaattttca ctgggatttc tttagcagtg
    52561 agtgcattct tccattggac agcaggattt gcctttagtg ccggatttgt cgattacttc
    52621 ctatctttga aaaatccgat tgcgaatcag ccattgatgt tgatcgtcca aggattagta
    52681 acagcagtga tttactactt tggctttaac tttgctatca aaaaattcca tctgatgact
    52741 cctggccgcg aggaagcaga tctttcagat gacgatactg caacgactaa ttcagacaat
    52801 aaatatgcgg cacaagcaag caaaatctac gctgcattag gcggagccga caatgtaact
    52861 tcgatcgata actgtactac acgccttcgt ttgcaagtca aagatacagg cctgatcgat
    52921 caaaataaaa tcaaagccac tggcgtacct ggtatgaaga tcatcgacgg aaaaaatgcg
    52981 caagtcatcg taggtacaga agtacaattc gttgcagatg agatggcaaa actacatggt
    53041 ggtgctgcag cacgacctgc acaaacaaac accgtggtta aaacagaaac atttgccggt
    53101 gaaacgatcg aacaagatat ttacgctatc gcaaatggga aactgattcc aatcactgaa
    53161 gtttcagatg atgtattcgc ggaaaaaatg atgggtgacg gctatgctgt attaccagaa
    53221 aatggagaaa tcttctctcc aatcgctggt acgatcacaa acattttccc aacgaaacat
    53281 gctgtcggaa tccaaacaga tgctggtatc gaagtcttgc ttcatatggg catcaacact
    53341 gttgacttaa aaggcgaacc attcacttta tatgtagaag aaggtcaaaa agtcgcaaga
    53401 ggtcaattga ttgctttagt tgatcttgcc gctattcaat ctgcaggcaa aaacacggat
    53461 atggtcgttg tattcacaaa tggcgacaaa gtccaaagct tagaaatcga acccgcacgt
    53521 gatgtaaaag caaatgataa aatcggctct gtttccaaca aagcctgagc catcgtcttc
    53581 cccagacttt tttatcgata aacaaacagg agctgagaca aaaatcttgt ctcagctcct
    53641 ttttccgaat aaaaacggcg ttctcctgcc aactccgcgg taataagtcc agctaaacga
    53701 aacatatgaa gagctatttt ttatttgact cttcttatta cttgatgcag aacagctttt
    53761 tcacaaaatt tttcttcata ctcaaaacta atcggctttt tcacaacctc tttatacatt
    53821 attcctgatc caatatttct tttaatgctg cttcaagaga agttaatggt tttcccaata
    53881 ctttttctaa atcatcagag gaaatagcta actgatcctt tttaatatca tgttggatcg
    53941 ctaaaaacat gtcagctgct tcttgaggga atccggcttc ttttagattt tcgacaaacg
    54001 ctgcatcact tgcttcaata atttctaact ctttacctgt cgcacgctct aatgccttgg
    54061 ctaattcttc atagtcagtt agattgccgg ataattctaa gatttctgga gagtcacttt
    54121 ctactagtac ttttgctgca gcttctgcat attcacgttt caatgcccaa cctgtttttc
    54181 catttcctgc agcataaacg aattgaccag tttttaaagc ctgcccaatg ataggtaatt
    54241 cattctctac ataccaatta ttccgtaaaa atgtatggga aatacctgaa tccttaatca
    54301 ttttttcagt gaattggtga tctggcgcta atacactgat cgagtgatcg gcatctgcaa
    54361 aacttgtata agcgatataa gataccccag ctgcttgtgc tgccttcact acattcttat
    54421 gttcggcttg acgatttcct ggaacgccag agacaaaaag caatcgatct attcctttca
    54481 acgcttcttt cattgagtct aaatcatcat aatcaccaat acgtatatta aatccagctt
    54541 ctttcagtgc ttctcctttt tcttcactac gtactagtac atagatttca ttttgtggaa
    54601 ccatcttttt taagaattcc agcgcataac caccaaaacc tccagttgct cctgttacta
    54661 aataatgcat atttgccact ccctattctt tttatttgtt aagatttaca gctgtacatt
    54721 tataaattac acctttatca taaagagtgt ggtaagataa gtcaagcaaa aaaaatgaaa
    54781 ggatgacaac tgatgaagta ttctctgcaa tttagtgatg caatccatgt acttgcctat
    54841 attgaaatgt ttcaagatac ccgatcactt tctagtgaga tgattgccag tagtatcgaa
    54901 acaaatgcag caaatgtacg taaaatcatg agtcagctca aaaaatccgg tttgatcttt
    54961 acaaaaaccg gaaaaccgca gccttccctt gccaaaagtc cagatcagat ttctttacta
    55021 gatgtctatc gcagcatcga aggtaataca cagcttatcc aagtcgatcc aaaaacaaat
    55081 ccaaattgcg tcgttggtgc gaatatccaa gaagctttag aagaaagcta cgctcggctg
    55141 cagaaaaagg cagaagaaga aatggctaag atcacacttg atagtctgat acataaaata
    55201 gccgttttgg aaaaagaaaa aagaccagaa aacacaggcc tcgtagagag atttttataa
    55261 ttctctctac tgtgcctgca tttttctgat cggaatcgtc tacataaatt cttttattct
    55321 ccgggggaca aaagccttgt catgcccctt tttcctctct aatgctcagg tcaaagcgct
    55381 gaagtcatga cgtcttgata aacggtgttc aagtagctga ccctcggcat tagttctgaa
    55441 aaatgcaaaa tatggaaagc tatttcccat ttttcctctc taatgctcag gtcaaagcgc
    55501 tactttcacg acctctatat tatcatggtt tattgactac cggtatccag atttctccca
    55561 tatatttccc gttggtaact cccatttcga ctacagcatt tggaccccca acataggcgt
    55621 aatcttctac ttctcttaaa acatgcccaa aggccgtatt cgtcaaatca tttcttaatt
    55681 cttcaggcga ttctgctaaa gcgcttacaa caagatacgt tccttttggg aatgggatga
    55741 ttcgcgtagt gtttggaaca tcctgactcg tttgaacacc gacatagtac atcattttcc
    55801 cgttataggg ttcgttgact gtaaagaaat aatgattttc agcagcttgt ttcaatgcat
    55861 ctattgttcc attaccgata actttttgct caaatgcttg tttctctgca gccaaaccga
    55921 caaaatccgt attgctactc ttcaattcca caccaatacc cgtcaccgta aaatctggtt
    55981 tttcttcgat cctatacttt gccatttctc ccaccctttc tattatatta agttcatctt
    56041 acataaaatt aaagggaaat gacacgatta cgctcttttt tctagggata tttttatttt
    56101 ttaactattt ttttgctttc actgcaatcc aaatctcact gtaaacatta ctgaaatcct
    56161 ctccccattt tgtaaaagag atctcgggag cttcgactaa cccataatct gaagaaggaa
    56221 gccattctgc atagattttc ccccaagtat cttgtaaagt ttggggaaat ggccctttat
    56281 taggaaaaat ggcccaagtg tgttcttcta tagcaagcat ttctaaatca gcgtacggat
    56341 tttcttttgt cgtagcaaag ccaatcatgt gcatcaaact gcccttttct tccaagcggt
    56401 ctccatcaaa tccataagaa acgttgatta cttgatttgg atataaatct cctaacttat
    56461 gcatctcttc cctttgagtc tccgtgatcg tctgcgctaa cttttgtatt tcttgattga
    56521 ctccttcaaa tttgacagga acttttttcg ccacacctgc cacataaaac tgttctttct
    56581 tttcgatacg aaattccatc gattttcctc ctctgacatc aataaaaaat gtcaagcgtg
    56641 gaaaagattt ttgtatgccg tatctactga tttctgaagg cagatatcct gaccaatcac
    56701 gaaaagctct tgaaaaacct tcgactgttt catatccata tctaaacgcc gtttctgtca
    56761 ctcttgatcc atctagaaga tcgcgattag ccaaagccaa tctacggttt ttgatatagt
    56821 ccattagcga catccctgca ataaacgtaa agatgcgttt taattgatat tcagagattc
    56881 ctgtattttc ggctattatt ttataggaaa gtccttctgt caaatgttct tcgatgtaat
    56941 cgatcaattg gttcagatct ttaagcatat ttatcttcct ccttgattgc ctttttatca
    57001 tattatcaaa gaaagtcaat tacttgatga atcaggaacc aatttagtca gatgtagaaa
    57061 atgttgtatg gatctaaaga aaattctcaa gcagcgtttc gtaacggata attggtatta
    57121 tctgcctatc tatgttttac ctttagaaaa ataaattttg gggaagacag attctaagta
    57181 aacaaagcgg taaaaatatc ttttattccc ttagttaatc cgcttactac ctactgtaca
    57241 aagcaaattg ttgttcaaac tgctgatcag aacgctgctt ggatttttct ttgcgataca
    57301 tcatacctct tttatcaatt ggaacaatta tttatttcta acaaaatcac ttcatttttg
    57361 tcagataaat aaaaaacaaa aaaagttcca tctttaaaac acgctattct tttacttttt
    57421 ctcacattct ctaagaaaag aaaaggagaa tgaatttttg acaattcgag caaaagtgat
    57481 tatcaaatat gtaaaatcag ctactttttt cttaaacgtt tctttatact aaatataaat
    57541 aagtgtttca tgaaaggaga actagatgaa taattggctt gagtattttc ctgaaaacgt
    57601 tttggaacgc ggttacagct atcatctgca cggttttgtc cgtcatttga actatacaag
    57661 caagtacttg tccgcaacag tttctggcac ggaagattat aaggtagtga tcacttggga
    57721 tgaaaagacc aacatgactt gtgattgtct atatgccata gaaggaaaaa aatgcaaaca
    57781 catggctgct gtcttattcg cttacgaaga acgtccaata aaaaaatcca actactcact
    57841 ttccgaactc tcgtcccttg tttcctccgc tagttcctct cttgtacggg agcttttaac
    57901 agagattctt atagaacatc cgcactttat cgaacgcttc aaagttaaga tgccatttca
    57961 tgcaataaat tattcagata aattaacaac tatcatccat aaatacgatc atattatcaa
    58021 gaaaaacaaa aacaggaaaa cagcgaagtt catcatggag atgcgaaagt tcatccaaga
    58081 agcagttgaa tcgcttattc agcaaaatgc ctatcttccc gcattcgaat tgatcaatga
    58141 agtgattgct actctcgaaa cattctattg ggagcctgag gatgaacgaa cccttcttct
    58201 gatagaggac tgttattatt tatggaaaga attattagca gaagcacctc atgcagaaaa
    58261 aaggcaaatg ttctcttggt tcgtctgcca agtcgatcat actgacgcct cttattcaaa
    58321 acgctactct ataaaaatcc tgaaagaaga ctttcgggaa aaagaatttt ctaaccaaaa
    58381 gaaaaaaata gataaaaaac taaagaaacg gtaaagaaag acgatttcaa tgaaaaatag
    58441 caagtaaacg ataacaacca tcctaaatcc acaagaaata cagcagacct tgctttaaaa
    58501 acacgaatca tgcaaaggat gaagtaaaga agacttaacg cgtacccaat attagtcatt
    58561 tgactattag gtacgcgttt tgttttataa gtcatgacaa atttccttcg ttgctggata
    58621 gattttccgg cattgttgat agattttatg atacttttct acattttgta agagaggttc
    58681 cgctgcatct gtatattgga taaaattctg acaacaactt tcaggtgtgt cgaaccaccc
    58741 taaccctagt gcagcaatca ttgttgcgcc taatgcaggt ccttcctcca tacttaaaca
    58801 atagaccgtt gcatcgaaaa tatcagcttg gatttgtagc catgcaagat ttttcgcgcc
    58861 tcctcccacc gaaacaatac gtgtaaatct gcgacccgct agttctttac gtttcaatcc
    58921 caccattgac aaatgctcat taaaaattta gaatattcac aagtttaacg acaattatga
    58981 aaatttatgt cgtgctaaag gagttttgtt attggatgaa aagttagata taaaaactgc
    59041 gatcaaagac acgttaccta ccgttttcgg ttatatcggt attggacttg catttggtat
    59101 cgttgggaaa gctgccggat ttcatccact agtcgtcacg ttgatgtccc tgctggtcta
    59161 tgctggttct gcccaattta tcacagtcag catgcttgct agtcacagcc cattgctttc
    59221 catcgttttc tcgacctttc tagtcaattc ccgaatgatt ctgatgagta tgacgattgc
    59281 tccttatttc aagaaaaatc ggctgcttca aaatctgctg attggcacat tgctgacaga
    59341 tgaaagtttc gcactgggaa tgaataaatt gaactatact ggacaaaagt taaactttcg
    59401 ttggatgaat acagctaatt ggatttctta tttgacgtgg gtgggttctt ctcttgttgg
    59461 cgcactttta gggaatttta ttactgatcc gaaaaagttt ggtttggatt tcgccatcgt
    59521 cgctatgttt atcgggttac tttatcttca agtcatttct gatagaaaca cctctaaacg
    59581 attacagttg atcctgattg gtctcacttt gattctggta tatgtcggac tgatttttat
    59641 cccaagcaac ttagtgattg tagttgtaac actgattggg tgcggattgg gggtgtggat
    59701 caaacatgcc ttcttttgag tttacattgc tgactatttt aggttgtact ttagcaactt
    59761 ggctttctag ggtcctacca tttgtcttac tgaaaaaatt cgatttaccg caaccgttgc
    59821 ttgagtattt aagttttgtc ccgatcgtca ttatgtctgc tttatggttc agcagtctat
    59881 ttacccaaaa tatcggacat ctgccgcaga tcaatctcga aaatgctttg gcttcagttc
    59941 ctacactttt agctgctatt ctttcaaaaa gcttattggt gatcgtcttg gcaggaattc
    60001 tttccctttc gttgattcgc ttattataaa taaaaaaaca agagcttatg gcaaattact
    60061 gtcatgcgct cttgttttta tcaaagtcaa ataagaaaaa aatcggcgta ttcttgctta
    60121 tccgttgaac ggaccactaa caacgacttt tcctaacata tgtcctgttt ctacgtcttt
    60181 ggttgcttgt ttcaagttct tcgcattcat cccatctgaa tagaccttgc tcaatgtact
    60241 gcggataatc ccttcatttg ctaaagcagc aatgtgcgct aaagcttctc cttgcgtttc
    60301 gatttcatag ttatagtctg ttttagcgaa catatactcc cagtcgaagc tgatagattg
    60361 gtttttccaa acacctatat ctaacggctc tttgatccct acgatcgttc ccacatgtcc
    60421 aaatggtcgg acaaggtgct tgatttgatc aaagtagcgg gtaatatcga ataatacagc
    60481 gacatactct acttgatcga ttcctaattc acgaaaactt ttacttaagt cgtgatgata
    60541 atcgattgga tagtctacac ctgttttttt cagccattca aaattcttcg gacttgcagt
    60601 cgcgtagact tctaggccag cccaatgcgc tagttgattc aaaatcgaac cgacgccccc
    60661 ggatccgttg atcactaaga tttttttccc gcgattggca ttttcttctg gagttagacc
    60721 aaatttttca aataacaatt cataagcggt caatgaggtc aacggcaagg ctgcagcttc
    60781 ttcatctgaa agattttttg gtgcaagagc gacaatacgt tcgtcaacta gttggtattc
    60841 ttgattgctt cctgctcttg ttgttgtacc tgcgtaaaaa acgcgatcgc cgacagaaaa
    60901 tttttgcact tcgtcaccta cagcaacaac tttcccgact ccatcaaaac ctaagatacg
    60961 taaagcattt cttatcccgt tatcttggcg aagtttcgta tcgacaggat taacagatac
    61021 tgcgttgact tttaccagaa gatcccgtga actgggtaca ggtatctgtt ctttttcatc
    61081 aataaagctt tttggatcat cgatcggcaa cccttcataa aaaccgacta ccttcattaa
    61141 ttccttttct gacatacgaa ttcctcctta gcttcatcaa gttggagcat ccatacagtg
    61201 ttcatttcaa tatatatagt atgctatttg ttccaccttt tttattcatc ataattattc
    61261 tcttacttaa agtaaactat ttgcactttt ttggttaaaa aagaggttgc gacaagactt
    61321 ttgtcacaac ctcttataaa cggtgttctc ctaccaactc ttcggtcaca agtcaaaata
    61381 ttcatcaaac atgagaagct gttttttgaa attgctcctt gtgactcaga gttaaacggc
    61441 aggctcacaa cctctgatat aaacggtgtt caatcaactg accctcggta ttagctcaaa
    61501 aaacgacaaa atatgaagag ctatttttgt ttggctgttc ttattacttg atacaggaca
    61561 gctttttcac gacctctaat tcacggtgtt caagcaagaa atcattgttc actgaaaagc
    61621 gttggatgtt ctttttcaaa ggtctctaag atctctcgta cttcatcagt agatttcgta
    61681 ttcatcaact gaactcgcaa gtcatttgct cctggaaatc ctttgatata gattttaaag
    61741 aaacgatgta gtcctgtgat ggaacgcggg atgatttctg aataatgatc ttgcagatct
    61801 agttgcagac gaagtagtcc gatcagttct ttttctgtat gttccctcgg gtctttttca
    61861 aatgcataag gattcttgaa aatccctcgg ccaatcatga tgccatcaac gccatatttc
    61921 tcggccaatt cttctcctgt ctggcgatcg gggatatctc cattgatcgt gattagtgtt
    61981 tgtggagcga tttggtcacg taaagcaatg attttaggaa tgacttccca atgtgcatct
    62041 actttactca tctctttacg cgtacgcaaa tggacagaaa gattggctat atcttgatga
    62101 agtaggtgac tgatccattc ttccatctca gacatttccg tatagccgat acgcgtcttg
    62161 acgctgacag gcaaaccgcc agctttagct gcttcaatca attgtgccgc tacttctgga
    62221 cgaaggatca agccactgcc ttttccacgt tctgctacat tagggactgg gcagcccatg
    62281 ttgatatcga ttccttggaa gcccatttct gccatagcaa tgctcatttc tctaaaaaat
    62341 tctggcttgt ctccccaaat atgggcaacc atcggctgtt catcttctgt aaatgttaat
    62401 cttcctcgta cactgtcttt tccatctgga tgacagaaac tgtctgagtt tgtaaactca
    62461 gtaaagaaga catccggtgc tgctgcatgc tttacgacat ggcgaaatac aacatctgtt
    62521 acatcttcca ttggtgctaa aacaaaaaaa ggctttggca gctctttcca aaaattagta
    62581 gtcatttatt tgttactctc cattctatca agcagtgaag tcgcaatctt tctcaaaaac
    62641 attgtcatta tactaggaaa caaaaaaaga agcaaagtga acagcttaaa agatgtttct
    62701 gattgagcaa aaaaaagact gtgacaaaaa tcttatcaca gtccattttc cggaataaat
    62761 ggtgttcaaa agcttgcatt tgcggtaata agtccaacca aacgaaaaat aggaggagct
    62821 atttttgttt ggctgttctt attacttgat gcagaacagc tttttcacaa cctctccact
    62881 aaacggtgtt caatcagctg accctcggta ttcgctcaaa aaacaacaaa atatgaggaa
    62941 ctattttccc gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctttt
    63001 ctaacttctc aatcctcttc ctttattgat caaataccaa gtaacggcgt acaaaacaac
    63061 gatgaataac acaagtacga tcatcgatgt tgctactggc acatcgatcg ttccaaggaa
    63121 tccgtaacgg aaaccggaga tcatataaac gatcggattg acttttgaaa cagcttgcca
    63181 aaagggcggt aacatagaga tggcatagaa aacgccacct agataagtta acggctgcaa
    63241 gacaaatgta ggcacgatcg atacatcatc ataagactga gcaaaaatcc cgttgagcag
    63301 tcctgctaat gaaaacaaga ttgccgtcat caataatgta atgatgacca tgaaccatga
    63361 atacacatga agtggtacaa agaacaagga aatgatcgtt acgagagagc cgacgagaat
    63421 actgcgaccc acaccaccaa tcacaaagcc ccaaataatc acatgcgtag gaacaggtgc
    63481 taccaagatt tcttcgatat ttttctgaaa tttttgagag aagaaggacg aagaaacatt
    63541 ggcatacgaa ctagtgatag cagacatcat aatcaaacca ggaacgatga attccatata
    63601 tgaaaaacca cccatgtcac cgatccgccc accgatcatt tttccgaaaa taacaaaata
    63661 caaggatgtc gtgatcactg gcggaaccag tgtttggacc catatacgca aatagcggtt
    63721 cgtttccttg atagctaaac tttttaatgc agtaaaataa agattaaaca tttttctcct
    63781 ccgtatgatt attttcttct gtgattttca agaacagttc ttctaaacga ttcgacttat
    63841 tcctcataga aagaactttg attccttgtc ttgtaagctg atcgaagatt ccgttcaccc
    63901 cttgatttcg ttcaacttcg acagcgattg tctgctcatc ttcaaatgta caagcatatc
    63961 cttcaatcac aggtttggta tcatatggcg ctaaatcaaa gataaatgtt tcaaattgca
    64021 gttttgacag aagctctttc atacttgtat tctcgatcag ttcacccgat tggatgattc
    64081 cgatgttgcg acaaagcatt tcagcttctt ctagataatg cgtcgtcaaa atgatcgttg
    64141 taccattttc gttcaattct cgtagaaact cccacatctc gcgtctcaac tcgatgtcaa
    64201 ctcctgctgt tggttcatcc aagatcagca aacgtggttc atgcatcaat gccctagcaa
    64261 tcatcagtct tcgcttcatt cccccggaaa gcatacgtgc acggacattt ctcttttccc
    64321 aaagattgga ctgcttcaaa tatttttcgc tgcgtttcat cgcttctttg cgagagacac
    64381 cgtagtagcc tgcttgattc acgacgattt gctggaccgt ttcaaaaggg ttaaaattga
    64441 actcttgtgg aaccaatcca atctgttgct ttgctcgaac tagatccttg tccagatcat
    64501 aaccgaagac attcactttt ccagatgttt tattgactaa agaagtaata atcccgatcg
    64561 ttgtagactt cccagctcca tttggcccta atagcgcata gaaatctcct tctttcaccg
    64621 aaagatcgat tccccgcaat gcttcgaccc cacttccata gatctttttc aaattattta
    64681 tttcaagcgc atttgccatt tatttcctat ctccttatag acatgattct taattgtatc
    64741 atggaataca gcagatgaaa aaacaacttg gcttccacac aaaaacacac ctgctaacaa
    64801 agaggagatg tgttttctag ttcatgatca tcttcgatag aataactatc taaacaactc
    64861 tggaactttt aaaatcataa aagtaccgac agcaactact acgatgacat atagaagatc
    64921 cttataactg aggttcttgt cttttttatt catgttaagc tttcctccgt ccttttatcg
    64981 aaagcttttt tcttttattt taaccgaaat aaataaaatg gaaatagtta ttttcaattt
    65041 ctgttttcgc tgtttgtttt acggagaact ttgccatgga acgtgcgtct cgtcgctgat
    65101 gctaagtttt ttcgataaaa gctgctagaa ggaagacagc gtggtttatt ttgtatcgtc
    65161 ttttgctaaa tcttccaaga tcatctggac agcagactcg ttcccattga attctgccac
    65221 ttttttggca tcaatgtact tcttttgata atcgtctttt tggacccacg catcatgctt
    65281 cgtttgataa agttaatcaa acggatacca ctgacgctgt tcatcgaaca acaaactttc
    65341 tttttgggcc tgttcaacta tggatttagg ataattcaaa actttcagca aggcaatcgc
    65401 atttcgggtc cttgaaggtc cttcttttaa tttgaaatca aaactgattc cttttccttc
    65461 tgttacttgt tcttcaaagt ggacattctc acaataattc tttaaaatct ctgtcaattc
    65521 gatatcatgt gtggcgacaa atgctaaaga tggatactcc gcaagccacc gaacgactga
    65581 agcggaagaa gcaatccgtt cgatcgtatt tgttcctttt aaaatctcat ctacgaagca
    65641 gtagcagcgt tctttggaag ccacttggtc cagcaaacgt ttgatcgatt tgatttctga
    65701 aacaaaataa ctgtcgcctt caaataaatc atcttcgatt gccatggaag tcaacacatg
    65761 tccaggttgc agggtaaact gttctgcaat cgctgtttgg atcgtctgtg ctagaataca
    65821 gctgatggct atacttttga catacgtaga ttttcctgat gcattggaac ccgtgactaa
    65881 tgtattcttc tgccagttga ctggattaac taccgcttct tttaacaatg gatgatagat
    65941 atctttcgct gtcacaccgc cctcagtaaa ctctggtcgg caagtgatcg gcatataggt
    66001 gcgataattc aaaacggctg ctgcaacttc caattctccc agcaattccc acagcttgat
    66061 ggcttcagtt gaatgctttt ctaatttagt gagaacgaaa tgataggaga taaatggcag
    66121 catgaacatg atgttgacat attcaaaaat caattctgct tcactcccgc tcttcattcg
    66181 aaatgaaaaa cctaatttag ggatgtctct taatggttta gtttgctgtt tcagctcttt
    66241 ttgaagtggt gtcgtcattt ttgctaactg attggcggct gaaatcgttg aaaccaaata
    66301 actcatgcta ttcagctctg tttctagtgt ttgtttcttc actagataat agaccgtatt
    66361 gaatactaag ccaccgattg ctagatagat tcctagtact tgccctaaaa gaagcaaacc
    66421 tacacccacc agcggaagca agccaagaaa aataaataaa cctacgcgtc caatcttttt
    66481 actttttcca tccgctagat attgttttgc aaaattatga tctttttttc ctaaacgagc
    66541 gaattgatat tggattcttt ctctcagttg aggattttcc tgataaaaag caattagttt
    66601 ttctaactga taatcttctc caaaatcaaa gctacgtaaa cgctgataca acgcttctga
    66661 acctacacta gaataggtac tgttgatccc ttcaaatact tcgaacatat ccaagtcata
    66721 ccaagtaaga tcgtcgattt cactatccca tgaacggaat tttttctccg tgagccacgc
    66781 atccttcaaa ctttcttctt tatcaaatct cggttgataa ggaatttttc cccaattact
    66841 acgaactgtt tcctttactt tcaaacgtga aaaaatgtct aaaacaacta ataaaataac
    66901 aactgcaata ataattaaaa cgataaattc tctttggccc atatccctct ccgttccttg
    66961 atttgttagt tttagtatag cactgttgcg ctatttgaaa agggggtaca aaaataactg
    67021 tcttcgttac ctaattcgta tcaatcacac caaaataaaa acaccttcca aaaaagaaga
    67081 tgtctttaaa acgagataca attttttgtc attcacttca ggtaaattag agccaattaa
    67141 accctccgca acttgacgga gatggagaag atgcccccgt ctaatctagc ggtcatctct
    67201 cctcccattc cttccaccaa tttttttgac aggtaaagcc cgattccgct agattccgta
    67261 tttgtgcggc tggtattttc ggtataaaaa cgctggaaga ctttttcaac agaggtttgc
    67321 gctcctggtt tgataggatt ggccactgtt aatcgaatga atgaatcctc ttttgaaaat
    67381 gtcacctttg cttgtccatc tgcataacgc aataaattct gtatgatatt ttgcagcact
    67441 cgcagcaaca tgagcggatc tgctaataca gttgtattta tcgagtgttc agcgaacgct
    67501 acctcgatat ttttctcaga aaattgttca taaaaagaga aaaatacttc ttccacctct
    67561 ttagaaaaag aaagcgtatg gagatccatt tctttttgct tcgtctctat tcgagcaaga
    67621 tcataaaact gatccgtcat actgagtaat cttgcaacag attgtttgat gatcgttaaa
    67681 tacttctccc gtttctccgt atcctctacc tgttccagta attgtacata accgttaata
    67741 gcagtcaaag gagttctgag atcatgagaa aggccgacga tcgatagtct gatgttttct
    67801 tccatttctt gaaatgcttg tcctttttgt tcattttcat ccacccatgt attcagtgca
    67861 tctactaggt ccattagatt cttttctcga aattcgactg aaagacgacc accatattct
    67921 tgtcgttcag aaagagtggc gattttctta gttaatctct tgatttccct ttgcaggaag
    67981 aaaataaaac ttcccataaa gataacaacg agaagcaaca gccacttaat caaatctaaa
    68041 ccccactccc cacaccgtat gaatatacac agcatgtgcc tttgctagtt tccctcgaag
    68101 attggaaata tgcatattca ctgttttctc actatcaaaa tatggttctt gccaaactgt
    68161 ttcataaaga tttgctcgcg aaaatacttt tttcggatgt tctaaaaaaa gcttcagcag
    68221 atcgaattct cttcctgtca aatggacagc cacaccattc acatttacat ccctcgactc
    68281 tttgtccagt aagatttcct tgtaatagat gcgttgcgac agatctttta cttggacaga
    68341 agtctgatga cgaagttgga tgccgattcg taacaacagt tcttcgatat caaatggttt
    68401 cgtcacatag tcatccgctc ctgctgccaa caaggaaact ttatctcttt gatcgctttt
    68461 tgctgaaaga acgatgatcg gaacattcga tgtctgtcgg atttctgcta acaatgcttc
    68521 acctgaaagc cctggaagca tgagatctag aaggatcaaa tcgacaggat atgtgcttaa
    68581 caataatttt ccttccgtac ctgaataagc atcaagaagt ttgtatctct gttcaagaac
    68641 ctcctccagt aaagaatgaa cagcttcatc gtcttcgata atcaaaatag tttccagcag
    68701 gaacacctac ttaatgtcag atttttggaa aataaacatt cctagagctg atgataccac
    68761 gattgttact agactgacca gaatcatttt cggtgcttgc gaataagttg cttgttgcgc
    68821 aaagtccgta tacatgagcc acgtttccgt aaaccactcc gttagaaatt ccaagccttt
    68881 gatttttgcg aaaacaccgg gaacgaaggc cgttcccatg atataaagaa aagaaagaag
    68941 caaactgaca ctggtacttc tagtgatgaa tgtcaaagcc actggaacag ataatgtcgc
    69001 taatatcagc agaagcaata caggaaatac ttttagaaca taatttccat agtttttgat
    69061 tccctcaact tcaccaaatc cgaaagcaag tgtgtaagca atcatggcta gccccgtaat
    69121 caaaaccacg ccaagtgttg tgatcaaaag cgtaacgaga agtttcgaca cataataagt
    69181 cattcgattc cgtcctaaag ataacgtatt gcgaatcgta ccgttttgaa attcttcccc
    69241 aatataaaag cacgcaaatg ctgcgaaagc cagaagaatc catgcagcca ttttttccac
    69301 cattaaaatc cctgttgcac cgttgatgac tgtatccgtt gcttggttta attcattgcc
    69361 gtattttgta tgcatatacc attcgttcca agaataaaaa agcggaagta cgaccatcag
    69421 tcctagtgag acccacattt tacggctctt ccatactttt attttttcag cagttaatag
    69481 attaaacatg tggattgcct ccagttaatt gtaagaaata atcttccagt ttttgcccaa
    69541 ctaggtggat accatccaca ggaacttttg cctctaccaa tgcttgattg atggctgcta
    69601 cttggtcaat tccttcaaaa agctggataa cacggctaga ttggacaaaa taatccctat
    69661 aaccaagaga gtcgagaacc gttactgctt gttccgtcgc cgaagtgtca atttttataa
    69721 attgacgaga ttcttgtgcc aattcttctt tcgataattc tttgatcaag tgtccttcat
    69781 gcaaaatacc gtagtgagtg gcgatctgtg acaattcatc tagcaagtgg ctagaaagca
    69841 agacggtgat gccccgttct tttaccaaac gttggatgat ttctcgcatt tctgccatcc
    69901 ctgctggatc catcccattc gtcggttcat ccaaaatcaa aaattctgga ttcgtgatca
    69961 gtgcatttgc aatagctaaa cgctggcgca tacctaaaga gaaattcttt gctttctttt
    70021 tccctgtatt ttccaatcgc atcattttca gcaggtcttc gatttctcta tccgacacac
    70081 cgccgttcgc tgcttggata cgtaggttat ctcttgcagt taattctgga taaagagcag
    70141 gggtttcaat cgattgaccc atacgtcgtc ttgctgcctg caaatccgtc gttccaaata
    70201 attcgatcga accttcatca atcgagatca aacccataat agttctcata aaggtagact
    70261 tacccgctcc attctcccca atcaaaccat agatcattcc acgtttgatt tcgatcgata
    70321 ctttatctaa tgctttggca gcaccgtatt ttttggttat accagttgct ttcaagaccg
    70381 tttcatttcc aaaatccata cttatccttc tttcttattg ataagtgaag tatagttgac
    70441 gggtataaag aaagcagcca gaaatgtata aagaaagtgt aaattttcca attgaatttc
    70501 aagaaaaatc agactgtctc gcagacgtgg ttgagttgtc tgccaatcaa agagcgcacc
    70561 aaacagtgct aatccaagtg gactggccac catggtaatc gttgttatcg ttgacatcag
    70621 acgtccttgt atatgcgttg gaacttctcg ctgaagccag accatataaa aagcaaaaga
    70681 aaacattaat ccttaaaaac ggacttatga aaaataatac atgccgtttg ggatttacaa
    70741 ttagctacca aataagaggt tatgacaaaa gacttttcac aatcccttct tccgaataaa
    70801 cggtgttctc ctgccaactc ctcggtcaca agtcacaata tttatcaaac atgagaagca
    70861 atttttgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctcagaagc
    70921 ggataaataa tattgtttga tgatacttta tctttttccc gtttgtttat agatcgaatg
    70981 atattataga ccaagaatcc tacctattaa catagctaaa aacacaaaaa aggcactttc
    71041 caaattgtgg aaagtgccag aaaagttagg attaaggtaa ctgcgctcag cattgcttcg
    71101 cccagtacga ttctcgtaac tcgtgaactc gaacgataat cgcaattaac gttttgagaa
    71161 ctgtgaagct ttacgggctt tcttaagacc tggttaaaca aaactctatt ttattgcatt
    71221 ttacaggaat gtatttcatg cgaaattaat aagtctttgt ttatagagtt ttactagggt
    71281 ataaaaagtt gtatgttatc attacctcaa aacattacct cagcttggcg agttggttga
    71341 ttgaagaata aatcatttat ctagatatct caataaaaaa tgatttctaa gaaacttgta
    71401 ttttcgtgtt attatttttt tgccctatca aaatttctaa ttcttctagc gtaatatgat
    71461 tatgacacat aatcgattca attacttcaa tacctatttt tttcgagaaa gatccctttt
    71521 gttcactcac aaaaatactt tcagaagaca tatataagga acgaagtttt ggaattagta
    71581 tatcgtacaa atagaccacc ataaaatcgt ccttgcaacc attctcaaaa agaattaaat
    71641 ttgctgattg tgttacatat atcactgaat tacattcatg gtcaattcca aaaacaatgt
    71701 ctacttcatt ttcttttcta attcgcgcag ttacattttt caaactttca ccattactta
    71761 taaatgcttt agttactgta agctctgatg tttgttcaga tattcctttt ataatatttt
    71821 gttcatcagc cacattcccc ataaatccgc cgattccttt taagtaataa ttctcaccta
    71881 agagtcgctt gcattcactg aattgataaa aaaaccagtt aaaaaaatct tctggaaaaa
    71941 taaattctga tcgaacttta tttatatttt tagctcctat taattttata actcgattaa
    72001 tgttcacttg ctgcgatgaa catataactg aataaattga gttgtttaat tcaaaaaaac
    72061 aactttaaca tatgcatcat taattcgtta ttttttaggt agatattgat cattgttatc
    72121 tctctttttt tgcttcccat actccaactt agaaattgcc gttataaaat ttattttaaa
    72181 ggtgactttt tcccctgaag tatcggtagt aggaatactt aatacctcag cttctgagga
    72241 ggtatcccaa ttatagttat actttgcatc atcaccataa agaacaattc catttttttt
    72301 atcttgtgcc gttagcttta ctggttcgct tacttttctt gttaatatct tggactttac
    72361 atcatcgata ttgcttattt tatcaagctt aaataattta caaattaatt tcgtactagt
    72421 ttttatattt g
//
LOCUS       DAIGUC010000006        68494 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.006, whole genome shotgun sequence.
ACCESSION   DAIGUC010000006 DAIGUC010000000
VERSION     DAIGUC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.006"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            5..304
                     /locus_tag="NOB46_000389"
     CDS             5..304
                     /locus_tag="NOB46_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1057365.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            377..1738
                     /locus_tag="NOB46_000390"
     CDS             377..1738
                     /locus_tag="NOB46_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI1057366.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1760..2020
                     /locus_tag="NOB46_000391"
     CDS             1760..2020
                     /locus_tag="NOB46_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057367.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2034..2786
                     /locus_tag="NOB46_000392"
     CDS             2034..2786
                     /locus_tag="NOB46_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCI1057368.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2880..3485)
                     /locus_tag="NOB46_000393"
     CDS             complement(2880..3485)
                     /locus_tag="NOB46_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1057369.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3538..4512)
                     /locus_tag="NOB46_000394"
     CDS             complement(3538..4512)
                     /locus_tag="NOB46_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HCI1057370.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4890..5609)
                     /locus_tag="NOB46_000395"
     CDS             complement(4890..5609)
                     /locus_tag="NOB46_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1057371.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5736..7007)
                     /gene="celB"
                     /locus_tag="NOB46_000396"
     CDS             complement(5736..7007)
                     /gene="celB"
                     /locus_tag="NOB46_000396"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI1057372.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7160..8557
                     /locus_tag="NOB46_000397"
     CDS             7160..8557
                     /locus_tag="NOB46_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1057373.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8638..9078
                     /locus_tag="NOB46_000398"
     CDS             8638..9078
                     /locus_tag="NOB46_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1057374.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9226..9552
                     /locus_tag="NOB46_000399"
     CDS             9226..9552
                     /locus_tag="NOB46_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1057375.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9553..10302
                     /locus_tag="NOB46_000400"
     CDS             9553..10302
                     /locus_tag="NOB46_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057376.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10382..10837)
                     /locus_tag="NOB46_000401"
     CDS             complement(10382..10837)
                     /locus_tag="NOB46_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI1057377.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11264..11539)
                     /locus_tag="NOB46_000402"
     CDS             complement(11264..11539)
                     /locus_tag="NOB46_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057378.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11833..12648
                     /gene="thiD"
                     /locus_tag="NOB46_000403"
     CDS             11833..12648
                     /gene="thiD"
                     /locus_tag="NOB46_000403"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCI1057379.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12977..14428)
                     /gene="cls"
                     /locus_tag="NOB46_000404"
     CDS             complement(12977..14428)
                     /gene="cls"
                     /locus_tag="NOB46_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI1057380.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14769..17435
                     /locus_tag="NOB46_000405"
     CDS             14769..17435
                     /locus_tag="NOB46_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1057381.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17799..18551
                     /locus_tag="NOB46_000406"
     CDS             17799..18551
                     /locus_tag="NOB46_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1057382.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18573..19727)
                     /locus_tag="NOB46_000407"
     CDS             complement(18573..19727)
                     /locus_tag="NOB46_000407"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HCI1057383.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19912..22353
                     /locus_tag="NOB46_000408"
     CDS             19912..22353
                     /locus_tag="NOB46_000408"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HCI1057384.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22683..23387)
                     /locus_tag="NOB46_000409"
     CDS             complement(22683..23387)
                     /locus_tag="NOB46_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057385.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23574..23819)
                     /locus_tag="NOB46_000410"
     CDS             complement(23574..23819)
                     /locus_tag="NOB46_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057386.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23836..24687)
                     /locus_tag="NOB46_000411"
     CDS             complement(23836..24687)
                     /locus_tag="NOB46_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI1057387.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24853..25857
                     /locus_tag="NOB46_000412"
     CDS             24853..25857
                     /locus_tag="NOB46_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCI1057388.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26098..26454)
                     /locus_tag="NOB46_000413"
     CDS             complement(26098..26454)
                     /locus_tag="NOB46_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1057389.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26822..28009
                     /gene="tuf"
                     /locus_tag="NOB46_000414"
     CDS             26822..28009
                     /gene="tuf"
                     /locus_tag="NOB46_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI1057390.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="NOB46_000415"
     CDS             complement(28197..30788)
                     /gene="mprF"
                     /locus_tag="NOB46_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI1057391.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30814..31575)
                     /locus_tag="NOB46_000416"
     CDS             complement(30814..31575)
                     /locus_tag="NOB46_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1057392.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31742..32374
                     /locus_tag="NOB46_000417"
     CDS             31742..32374
                     /locus_tag="NOB46_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCI1057393.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            32433..33293
                     /locus_tag="NOB46_000418"
     CDS             32433..33293
                     /locus_tag="NOB46_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HCI1057394.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33478..35793
                     /locus_tag="NOB46_000419"
     CDS             33478..35793
                     /locus_tag="NOB46_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1057395.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35975..37816
                     /locus_tag="NOB46_000420"
     CDS             35975..37816
                     /locus_tag="NOB46_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCI1057396.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37840..38949
                     /gene="rpoD"
                     /locus_tag="NOB46_000421"
     CDS             37840..38949
                     /gene="rpoD"
                     /locus_tag="NOB46_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCI1057397.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39169..41268
                     /locus_tag="NOB46_000422"
     CDS             39169..41268
                     /locus_tag="NOB46_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI1057398.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41464..42327
                     /locus_tag="NOB46_000423"
     CDS             41464..42327
                     /locus_tag="NOB46_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI1057399.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42432..42905
                     /locus_tag="NOB46_000424"
     CDS             42432..42905
                     /locus_tag="NOB46_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI1057400.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            43001..43888
                     /gene="xerD"
                     /locus_tag="NOB46_000425"
     CDS             43001..43888
                     /gene="xerD"
                     /locus_tag="NOB46_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCI1057401.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            43907..44278
                     /locus_tag="NOB46_000426"
     CDS             43907..44278
                     /locus_tag="NOB46_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI1057402.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            44248..45045
                     /locus_tag="NOB46_000427"
     CDS             44248..45045
                     /locus_tag="NOB46_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCI1057403.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            45029..45598
                     /gene="scpB"
                     /locus_tag="NOB46_000428"
     CDS             45029..45598
                     /gene="scpB"
                     /locus_tag="NOB46_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCI1057404.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            45604..46320
                     /locus_tag="NOB46_000429"
     CDS             45604..46320
                     /locus_tag="NOB46_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI1057405.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      46402..46527
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            46650..47261
                     /locus_tag="NOB46_000430"
     CDS             46650..47261
                     /locus_tag="NOB46_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1057406.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            47639..49162
                     /locus_tag="NOB46_000431"
     CDS             47639..49162
                     /locus_tag="NOB46_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCI1057407.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            49399..50739
                     /locus_tag="NOB46_000432"
     CDS             49399..50739
                     /locus_tag="NOB46_000432"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCI1057408.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            50892..51629
                     /locus_tag="NOB46_000433"
     CDS             50892..51629
                     /locus_tag="NOB46_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HCI1057409.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51794..52015)
                     /locus_tag="NOB46_000434"
     CDS             complement(51794..52015)
                     /locus_tag="NOB46_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCI1057410.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            52046..53077
                     /locus_tag="NOB46_000435"
     CDS             52046..53077
                     /locus_tag="NOB46_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057411.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            53064..54467
                     /locus_tag="NOB46_000436"
     CDS             53064..54467
                     /locus_tag="NOB46_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCI1057412.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            54533..55168
                     /locus_tag="NOB46_000437"
     CDS             54533..55168
                     /locus_tag="NOB46_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1057413.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            55217..55897
                     /locus_tag="NOB46_000438"
     CDS             55217..55897
                     /locus_tag="NOB46_000438"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCI1057414.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            56032..57261
                     /gene="rpsA"
                     /locus_tag="NOB46_000439"
     CDS             56032..57261
                     /gene="rpsA"
                     /locus_tag="NOB46_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCI1057415.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            57443..58753
                     /gene="der"
                     /locus_tag="NOB46_000440"
     CDS             57443..58753
                     /gene="der"
                     /locus_tag="NOB46_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCI1057416.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            58996..59271
                     /locus_tag="NOB46_000441"
     CDS             58996..59271
                     /locus_tag="NOB46_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCI1057417.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            59506..60552
                     /locus_tag="NOB46_000442"
     CDS             59506..60552
                     /locus_tag="NOB46_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057418.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            60554..61813
                     /locus_tag="NOB46_000443"
     CDS             60554..61813
                     /locus_tag="NOB46_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI1057419.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            61819..62400
                     /locus_tag="NOB46_000444"
     CDS             61819..62400
                     /locus_tag="NOB46_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HCI1057420.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(62482..63357)
                     /locus_tag="NOB46_000445"
     CDS             complement(62482..63357)
                     /locus_tag="NOB46_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1057421.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            63505..63837
                     /locus_tag="NOB46_000446"
     CDS             63505..63837
                     /locus_tag="NOB46_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI1057422.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            63949..65157
                     /locus_tag="NOB46_000447"
     CDS             63949..65157
                     /locus_tag="NOB46_000447"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCI1057423.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            65311..65766
                     /locus_tag="NOB46_000448"
     CDS             65311..65766
                     /locus_tag="NOB46_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057424.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            66128..66403
                     /locus_tag="NOB46_000449"
     CDS             66128..66403
                     /locus_tag="NOB46_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057425.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            66416..68494
                     /locus_tag="NOB46_000450"
     CDS             66416..68494
                     /locus_tag="NOB46_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCI1057426.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
BASE COUNT        22620 a        11819 c        14353 g        19702 t
ORIGIN      
        1 aaaaatgaaa aatcggttaa ttgtcgcatg tggaagtgga gtagcaacga gtcagacaat
       61 cgctagtaag atccaaagta tgttagaaga tgacggcatc gcatttcctg tagaagcagt
      121 tgattacaaa tcgattcaaa atgagcttct aactgctgga atctatgtgt atgtcgcaca
      181 acctgatgag gaagtacttg aacaagcaaa agatttgggt attgaagtat ttccaggaat
      241 tccattttta actggaatgg gtgtagaacc tatttatgac agtatcaaag agttagtaca
      301 gtaaaggagg attgttggat aaaaaagttg gttcatagtt ttatttacta tatttagaaa
      361 gaaagaaggt ttatttatgg aagttttcca aaccattatc aattatgttt tgaacttagg
      421 atcagccatt tttgttcccc tgattatttt gatacttgga ttgttggcag ggatgaaatt
      481 aaaaaaagca ttcatgtctg ctttgacttt agggattgct tttagcggaa tgtctatggt
      541 cattggctat atgtctaacg cagtaagtcc agcatcagaa gcattggcta aaaatacggg
      601 aatcagtttg cctgcacttg atcttgggtg gacaggtgca gcaagcatca catggtcgtg
      661 gagttatgct tttatatttt ttgcagtaac gattggggtc aattttgtac tgttactttt
      721 taattggacg aagacgttaa atgttgatat gtggaatgtt tgggggaaag ctttaactgc
      781 ttatttagtt tattatgttt ccggtagttt ggctgcaggc tttcttactg caatggtcca
      841 agttatattg gaattaaagc ttggtgatat gtttcaaaaa catatacaag atctcacagg
      901 gattccatta gtaacagtga ctcattttat gacatctgcc gctgtcttgt tgctgccttt
      961 caatatgatc atggataaaa ttcctgcttt aaataaacga gcggatacga atgcattgaa
     1021 gaagaaaatt gggatcttct ctgaaaactc tgtaatggga ttcattattg gattggggct
     1081 tggctttgct gctgcgtatg gcgtttcagg ttctcttaat ctagcgatcc aaacagctac
     1141 agcattaagt ttgtttccta tgatctctaa aatgttcatg caatctttgt ctcctctagc
     1201 agacgctatg tcagaattta tgaaaaagcg gtttaaggat cgtgaagtat atatcggatt
     1261 ggactggccg atattagctg gtcgttcaga aatttgggtt actgctattt tacttgttcc
     1321 tgtgtttatt ggttatgcca ttattttgcc aggaaaccaa gtattgccat tagcagggat
     1381 tatcaactat tcgattgcgg tcggcggatt acttttaaca ggaggaaact tggctcgtat
     1441 gctgatcttg ggaatcatca ctatgcctat ttatttgtac ggggccactt accttgcgcc
     1501 aatactcagt gatttagcag aaaaaagcgg agcagtcgag ggaatcaaga aaggacagtt
     1561 gatcacatgg tcatccatag aagggccgga gttcagggtt ttatttgcgg aggcatttaa
     1621 taggaatatt ctcgctattg taggatgcgt gatttttcta ggactgtttg ttctacttta
     1681 taaatatatg ataaaagcga aagtaccgag tgaacgttat gctgaactac aaaaatagca
     1741 ttgaaatggt gggaaagtaa tgaaaagaga agagacagat aaaataaaat ggacagtcgc
     1801 tctttgtggt acacttctgc tatttctata tggactcttt actcagaata tcatcatcaa
     1861 tctattggtc atttttttcg cactagtgat ctataaatat ggaaatcacg ttttattcag
     1921 agagtacgat gaaaaaagaa aacggaaaat agaagaatca atgaaaataa aagaagctac
     1981 caaagaaata ttgagagaaa aaagttttat aaaaagataa tggaggggtc attatgtcag
     2041 atggacgtat gttatttgag agagaacgac aggacatggc acgtatcgta agagtgattt
     2101 tcgaaaggaa aaacacaaat gtcgcaggag ggaatttttc ctttaaaacc actgatgatc
     2161 aagggaaaga ctacatcatc atgacgccga ccatgatgtc agaagcctat ctaggagaga
     2221 tttctcctgc acaggttcta gtagtagaac caagaacgcg tagaatcgtt gacggagtcg
     2281 gtcatttaac tcgtgaaatc aatatgcatg aagcgatgta tgagactaat ccagctatca
     2341 aagctgtcct acatgctcat gcgcctaatg caatgttctg ggcgactact gggttgccta
     2401 tgcctaattt gacagaagcc acagctaaag taaaagagat tcctgtcatg gactttgagc
     2461 ctaattgctc tgaagaactt gctgaattga caagcgacta tgtaaaaaaa cagcatctcg
     2521 aattaccgca tatgttgctg ctcaactctc atggcgtatt gatcaacaca ggtggagaat
     2581 caggaatcga agctatccat aaagcactgc aaatccttga tacagttgaa tggaatgcag
     2641 aaattgccta caagcagacg atttttcaag cattagggat tactgacggt ttttattcaa
     2701 aaggtgagaa aatcggggga ttggaagagt tgaaacataa aacggctatt tataataaat
     2761 ctgttattgc agctggtgga gactaaccta tctgacacaa aaaactacga ctttcacaaa
     2821 atctgatcca gatcgatatc tgcttcaggt tgtattatgt aagtcgtagt tcttttcttt
     2881 tatttagtta agaggtggtc tgtccattcc ctcgcttgct tgatttcgtc catcgtcaac
     2941 tgatgacctg ttacagttag ctgaatagtc acatttgctt ggcgtgtttc gaattgatcg
     3001 gccaattctt taaaggaagc aggggaaacg attggatcgt tatcaccata agaaatccag
     3061 acggttttat cctctaatgt ggaacggctt tgatgaacac ctagagacat cggatggaaa
     3121 aacaaccctt tatttagctc ggtctcacgc tccaataata aatgagcagc gatgtttgcg
     3181 ccatttgaat agccgacaag cagccagtca cttaacggta tcagttcttt ttcgctgatt
     3241 tctttgattt tttcatggag tttatctgtt tctttttcca aactgtccag gtcgaattga
     3301 ttcaatccat tacgcttgaa aaaacgattc atcccatctt cttggaccgt gccacgaaaa
     3361 gaaagcaatg tactgtttgg tgcaagaaag tgagcgatat ccagtaaaga atgttcatcg
     3421 ccacctgtgc catgaagtaa gatcaaatgc ttgccacttg ttcctttttc aaaaatgtag
     3481 gtcattttgt tccctctttt ctgtttctat agatgcaaat gaagtagcat gaagagatta
     3541 ttcacgtttt ttatttgcat cacttgtatc gaaaggacgg acataagctt caatggcttc
     3601 acgacgttct tctaagaatg gaggaagaga tagtttttct cctgctgatt ctgctggttc
     3661 atcttcaagg aatccaggac catcagttgc taattcaaac agtacgtgat gagcggctag
     3721 gaagtactca gattggaaat agaaacgatc gacgaaacca gaatttggca attcaatctt
     3781 attgattact tgaatccagt attccaatgc ttctttgtct gctacacgca atgctaagtg
     3841 atggatattt ccaaatcctt cgattgcttt tggcaagtct gtccgatgtt caataatgat
     3901 gcttgcacca tttccccctt caccgatttc aaataagtag aaatctcctg aatggtctgt
     3961 ttctttgaat cctaagattt tttcaagaat caagcggata tgctctaatt gactgacacg
     4021 gacaaagaca ggtccaagtc ctgtgatcgc aaactctgtc ggtacattgc tgtttttcca
     4081 aggaatgcca gctgctacac cttgattgtt ttcgtcagag atcaattgat aatactgatt
     4141 atcgaaatct tcaaattcga tatatttttt gccgaaacgt tcattgattg ctgaatgagt
     4201 aacgtcatat ttttcaaaac gttccaacca aaagtctaat gctgcgtcac ttggcacacg
     4261 gaaagaagca cgagagatcg tatctgttcc tttttttcct tttggctgat ttggaaaatc
     4321 aaagaaagtc atatctgttc ctggcgcacc agtatcgtct gtaaagtaaa gatggtaagt
     4381 ttcgatgtca tcttggttaa ctgttttttt gattaagcgc attcctaaaa tatctgtaaa
     4441 aaagcggtag atttttgtag cgctagatgt cattgctgtg acgtggtgaa ttcctctgat
     4501 ttgtgtatcc atgataaatt tcctcctgtt aacttacaaa aagtaagtag ttgatttaga
     4561 catagtatag agggtgcatc tctattttgc aattaatttg tcttctaaag tatcaggaag
     4621 gaatcaagaa tggaaaagag gagggacgga tcaataaaat aaaaagactt acgactagct
     4681 gtatcgattt caaaaaaact agctttaaaa agctaacttt agaatcatta cgggtggtca
     4741 taagtctttt tatgctgagt tattttttca tttttgagct aatgcttagg atagaataga
     4801 atgttgattt cacgatctct tcttgttact tgaaactgct taccactgtc acgatctctt
     4861 ggtaaacggc tttttcacaa cctctttggt taagttgaac gcacatccag cacagaatag
     4921 ttccgaacat caaatcggtt tcggctggaa gaatattcaa tcggctgtcc atctttgaga
     4981 tagacgactt gctgaacttc cagtacagga tcgttttctg cacagttcaa atattgctga
     5041 tcatattcat cacttttatc tgcagaaata gcacgataag cccctgcaaa atggacattc
     5101 aattcttgat gaagatgatc atagatagag gctaacaaat gttctttttt taaacccggc
     5161 acaagatgga ctggcataaa ggtatgctct aaaacatatg gctcgccatc taagatcctt
     5221 aaccggtgaa tattgtagac aggttgctcg gcatcgatca tcaatcgttc ttggatatat
     5281 tgattaggga attcaacatc aaaatgaatg atttgactct tcaaagaacg atgtctgcgt
     5341 ttcatttgga gactcaaacc ttcatactcg ttagcgggcg atgtgtcttt ttgcataaat
     5401 ggatgattca agattttcgt tcctgatcct cgctgcgaat agacaagtcc ttccattgct
     5461 aagatattga tggctttttt gattgtcatc cggctcgcac caaattcttt taccaagtcg
     5521 acttgattag gcaaaaaact atcgagagga tactcttttg aacggatacg ttctcttaaa
     5581 atatttgcga tttcttcgta ttttggcacg ttattcacct cttctagagt ataacgaaag
     5641 attatgcttc cgacaactcg aagtagcatc tggaacattg tttattcgaa aaaagaggtc
     5701 atgacaagtt tttgtcacaa ccccttaatg atctattaag caatatctaa atctggttgt
     5761 ttatctagta ctttcaggaa tgggtaccag ataaaggcaa cgatgacaaa gtcgatgact
     5821 tgcagcatac caccaagcca tgaatttgtt gctaagacac cgcttgcaat gattggcaca
     5881 gtccatggaa cagagacgcc agttggtgca gggacaagtc cagcagccat taccaaataa
     5941 ttgaacgtcg ttacgattag aggtgccaca acccaaggaa taaggattgt tgcattcaat
     6001 acgatcggta gaccgaagat cgctggttca tttacattga aaataccagg tgctaaagct
     6061 aatcgtccaa catcacgata ctgtttcttt ttaagaacaa aggccatcaa taaaacgaca
     6121 gctaaagtca ttccagagcc accaatacca acagtgaagg tttccatgaa tggttttgtg
     6181 atgatgtgtg gtaattcttt tccatgttga taagcttcta agttatcaag catcagtgta
     6241 ttccaaatcg ggtccattac agagttgacg atgatttgtc cgtgaagtcc gaagaaccat
     6301 aagaattgga caaagaacaa agcaatcaat gttgcaggta aactacttcc caaaccagtt
     6361 aatggttttt ggatcacttc ataaacgacg tcatgtaagt tagcattgaa aataccagtc
     6421 atcacagcat tgattactaa gaaaatagtt agtgtcacta cagcagggat caaagcggca
     6481 aatgattttg ttactgcagg cggaactcca tcaggcattt tgatctgcca gccgcgtttc
     6541 gtgattctgc agtagatttc tccagccaag aaagcagcga tcattccaat gaacattcct
     6601 tttgcgccaa gacgatcaag tgaaagcaca ccagtcacat cttcaccgcc agcggttttc
     6661 attgcaaaag gcgtaagaat caagaagctg gcaaaagaca cggcaccacc gaaaatacct
     6721 tcaacgtcat aagattttga taaataatag ccgataccaa aagtaacaaa aaccgacatg
     6781 atgctcattg ttgcattttg cccattaccg aataaattcg ataaagttcc ctttgttgcg
     6841 tcactgaaaa aaggcaagtt attgataacg acaacgatcg aaccgaacat cgttaaaggg
     6901 aaggaaagca tgaaagcatc ccgcagcact gtaaggtaac gattttgccc taataaatta
     6961 gctaagggca tgattttctc agaaagcttg tccataaaac cgttcatttt tattcacctc
     7021 aaatttattt gcaatcgatt acatacaaag tataacgcca aaaattttaa atgtctagtc
     7081 attttcataa aaagtattga tttatttttt agggttcgtt atgattacgg tatcaagaaa
     7141 aaagagagga agtaaaaaaa tgaaaaccta cacattccca gaaaattttt ggtggggttc
     7201 tgctgctagc ggaccgcaaa cagaaggaag agtaagtgat gatggtaaag gagaaaatat
     7261 ttgggatcat tggtatgaat tagagcctga aaaattcttc gatcaagtag gacctgaaaa
     7321 aacttcgcaa gtttacacaa aatacaaaga agatgttcag ttaatgaaag aaactggcca
     7381 taacacattt cgtacatcta tccaatggag tcatttgatt ccagaaggga caggtgaaat
     7441 caatcaaaaa gctgtttctt tttatcgaga ttattttact gaattgctgg ataatggtat
     7501 tgaacctttt gtgaaccttt accatttcga tatgccacta ccactgcaag aaaaaggcgg
     7561 atggttatca agagaaacgg tcgacgctta tgtttcttat gcagcagcgt gctttgaact
     7621 gtttggagat ctggtcaaaa aatggtttac tcataatgaa ccaatcgtac ctgtagaagg
     7681 aggctacttg tatcaattcc actatccaaa tcatatcaat atgaaagaag cggtccaagt
     7741 aggctatcat gagaatctag caagcgcaaa ggtaatcaaa gcctaccatg aaggcggaca
     7801 tgatggtgag atcggaatca tcttgaatct gacaccaagc tatccgagag atgaaacgaa
     7861 cccagaagat gtaaaagcgg cgaagatcgc tgacgcattc ttcaaccgat cattccttga
     7921 ccctgcagtg aaaggagagt ttccacaaga gttgatcgaa attgtcaaag aattggctat
     7981 aatgccagag atccatgaag gagacctaga actcatccgt gaaaacacga ttgacctgct
     8041 aggaatcaat tactatcagc ctcgtcgaat caaagcaaaa gaaactccaa tcaatcacga
     8101 acatagcccc atgccagatg attattttga taattacgac atgcccaata aaaaaatgaa
     8161 tccatatcgt ggatgggaaa tttacgaaaa aggaatctat gatattttaa cgaatacaag
     8221 agaaaactat ggtaatatca aatgctatat ttctgaaaat gggatggggg tcgaaggaga
     8281 agaacgattt gttaacagcg aaggaattat tgaagatgat taccggatcg agtttgttac
     8341 ggatcatttg aaatacgtcc atcaagcaat ccaagaagga accaattgtg tgggttacca
     8401 catgtggaca tgtatggaca actggtcttg gacaaatgct tataagaatc gctatggctt
     8461 tatcgctgtt gatttggcac aagacggtaa acggacgatc aaaaaatcag gtcgctggtt
     8521 taaaacggtc tctgaaaaaa acggatttga tgcctgatat tttttgataa aacgttcaca
     8581 aaatgtttgt tctaacactg taatcgtgct acactaacag tgaaggaggc gtttacaatg
     8641 gtagatactt atcgtaatat tttagtagca attgatggtt ctgaaaaggc agaaaaagca
     8701 tttcttgagg caatcacgat tgccaaacga aatcaggcaa cgttgcacat cctgtatgtc
     8761 aatgaagtaa caggcaatta ctttggtgat tttgcatttg ttacaacaag ccttcaggaa
     8821 gaattggatg aggttgcgga aaaccagatg aaagaacatc gaaacttggc aattgaaaaa
     8881 ggcctgacag atatcgagac atatgttctt tacggttatc caaagacact gattgctaat
     8941 ttccatgaat cgaaagaacc aatcgatctg attgtcatgg gggcgacagg tctgaatgcg
     9001 gtagaacgtg cactagtagg ttccactact tcctatgtag tcaaccacgc atcatgtaac
     9061 gtcatggttg taaaataaat aaattaaggg aacagaaagc aaaaaagcat aacgcttctt
     9121 ttgctttctg ttccttttat ttttttgtaa aaaattactt tacctgatga agtaatcatg
     9181 ctattctaat tacaacgaca gatggagtaa tatggaggaa agaaaatgat ttcaagtgat
     9241 ggaatacgcg gatacaatga tgcgattatt ttatcgatcc ttaacaaaaa cgattcttat
     9301 ggatatgaaa tttctaaaac gattcgtgag aggacaaatg attcctatgt gatcaaagag
     9361 acaacacttt actccgtttt tgcccgttta gaaaagaatc aactgattgt ttcgtatcct
     9421 ggagaagtga ctcatggaaa aaagcggaca tattataaaa tcactgaaat agggcgtaat
     9481 cttttagaag aaaaaaagca agagtggctg acgacgaaag acgtagtcga tcaatttttg
     9541 gagggaaatt aaatggatac aatccgtaat tatttagaca gtctttttat cggagtacct
     9601 caaagtaccg agatagataa gctgaaaact gatttgttgg caaatatgga agaccattat
     9661 catgaattga tgggagaagg aaaaaatgaa caggaggcca tcggtacagt aatttcgaca
     9721 tttggttcaa tcgatgaatt attagaagaa ctagatgtcg aaaaaaaaca tcaagctgac
     9781 gagacggaaa caaacacagc ttctatttat ttaagcgaag cagaaaacta ctggaaagaa
     9841 tacagagcgg caagtctcca agtggcatca ggtgttctat tcattagctt atcttttgca
     9901 agttttcttt tcttttgttc agcaggatat gtgttcatgg gtatttcttg tctgattttc
     9961 ggtatagcat tagctgtcgg tttttttatt gcttctggta tgaaaatcac acgtttaaat
    10021 cactttttgc accatcggaa aatacctgaa aaagtattag cagaagcaaa agaaaaagaa
    10081 gaagagtatc agcgaagttt tggcttctca ctgattgcag gaattggatt atgtattttt
    10141 tcacttttcc cacttttggc ttctttaatg tggtatatgg atggtagtat cggtgcctct
    10201 atattttttg ttacggtagg aacgggtgtc ttcttgatca tttatggcag tctagtccgt
    10261 cattcttatc gtcaattcac tcaaagcgct tattactggt gaatgtattc agatttgtaa
    10321 aaatattcta tttatccggc gtagaaaaaa agactgtgac acgcttttgt cacagtcttt
    10381 tttatatata ataatttaaa aattcatcat ctaaatccgt agaattttct agattgctta
    10441 cccatgtaaa atcgttatag acagatttca gttgacttct gcgccattgt acagggataa
    10501 aaagacgcat gctatcttca ttgaatccga ctaataattt ctttccgtca gtaatgatgg
    10561 gacgttgtaa caaagtaaaa tgcgagacga tcagatcgac aagctctgag gtcgtacatt
    10621 ggtcgatttg gtctttcaaa tttttataat caatcgagcg tttagctaat agatcgtcaa
    10681 atccgttttc tgttaatgac aataaataaa atatctcttt ccttgttaaa ggctgtttag
    10741 gtgtgaaaat tcgttctctg taaggcattt gatggtcttt cagccagttt gccatcagat
    10801 ggtaactatg tgtgcgagaa gaatagatcg taagcataaa aaaactcctt aaatagtcca
    10861 ttaatttgtt agatctgttg agataaataa taggtaagga gctgtgcata agcattgatc
    10921 aaaacaaccc aaacatcatt agaaataact ttctaaagtc ttaaacttgc gacgagaaac
    10981 aactagacta atagaaaaaa tgtcttagcc atttggcttc ctgtttgttt ttttgcttat
    11041 gctgcagctc ctcgggaaag ggttctaaca atttgaagaa ggttgatgat tgatctagtt
    11101 taaattgtgt gaaatttgaa atctggtgtt tttactagat gaatcaccta acaactatga
    11161 ttataactta tagaacttct gttttgcatt cggttttgtt atagttgtta taaagtttta
    11221 ttttattaca gaacattttt aattaataaa gaacagttag aagttaaaat tgctgattca
    11281 catagagttt atgacttctt ggaaattctt tttcaatcag ttttttcatc tgtttatgaa
    11341 attctttttt ttcagtaaac ataaaggttt gggtatcgta accttcttca tgtaggaaat
    11401 agattattcc tttttctgtg ttttgcgtat aagcttttat actcctgtct tttttgaaag
    11461 aacagatcgt atagccatct atttggtctg gtagtcgttt gattttcttc aaaatgactt
    11521 ttttatcctc aagtttcatt tttttcacct gactttattt ttttcatatg gaaatcatag
    11581 cgcctttggt tatatgaaaa caagaaggat actgaaatat atataaatca aatagtggtt
    11641 atttattatt agaatagcga atacaaataa acgaccacta ttttctgatt tattgcaaat
    11701 gttttttcaa ataaatttga ttaccaagaa aaggtagtgg tatatttact gagggatact
    11761 ttgaaaaaca tatgatagaa acagtaacag tattatgaaa aatcttttta taaaaatgga
    11821 ggaatcgatt tgatggaaga tcagtatgta caagcaatga cgatcgcagg atcagatagc
    11881 gatggaagcg cagggatgca agcagatatg catacattct ttacaagaaa tgtttacggt
    11941 gtttctgtca tgaccgcatg tgttgcaggt aattcttacg gaatcggagc aagtgtgaca
    12001 ttgccaacag attttatcga caaagaattt gaactgattg cgaaggactt tcaaatacgt
    12061 gcagctaaaa caggtatgct agcagattca aagttgattg agacagttgt aaaaaattac
    12121 caaaaatatg attttggacc attagtcgtg gatcccgtaa tcgtaacgaa acatggaaat
    12181 cttttactag aagaatctgc tttgcaaagc ttgaaagaaa agcttgtccc tttggccgaa
    12241 gtactgacac ctaattttta tgaagcagaa aagctgactg gacggacatt agcagctgaa
    12301 gaagattttg tgcaagcagc aaaagaactg caagatatgg gtgcaaaaaa cgttatgatc
    12361 aaaggacatc atgctaaaaa tgcgcagcaa gaaacagtca atgactacgt attgttcgaa
    12421 tcaggaaaat cattttggtt aaatgcacca ttttatccta ccgaccggat caacggaact
    12481 ggcgattcgc tatctgcatg tattgcagct gagttagcga aaggaaaaac agttgaacaa
    12541 gcgatccgat tggcaaaaga ctatgtaaac cgtgcaattc gtgaagaaat aaatgtaggg
    12601 cacaaatatg gccccatcaa tcattgggca gctggtgaat tagagtaaaa gaaagaagtt
    12661 gtgaaaaagt tgccctgcat caagtaataa gaacagccaa gtaaaaacag cttcttatgt
    12721 ttttaacttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    12781 ggtcgtgagc ctgccgtcca gctccgagtc acaaggaaca agttcaaaaa acagcttctc
    12841 atgtttgttg aatattgtga cttgtgaccg aggagttggc aggagaacac cgtttgttcg
    12901 gaagaaggga ctgtgacaag atttttgtca cagtcccttt aatcttagta tatttttctc
    12961 tacttgaata aaaaaattat aggattggag aaaataatcg agaaatttgt tgcttgaata
    13021 atagccagtt agacatttcc ttgactgttt cagttgtcat ggatgaacaa tgtgtctcat
    13081 cttctttgaa ctgagtagca agttcttcta aaaactcagg atcgtaaatg acagcacttg
    13141 tttcaaaatt caatcggtag ctacgaatat cttgatttgc tgaacctacc atgcagattt
    13201 catcatccat tatcaatgtt tttgcatgga ggaagccgtt ctcatagaca aggatttgta
    13261 cattttcctt gatcagctgc cgagcataat attgtgttgc tcgataaata aaaggatgat
    13321 ccggtttgtt gggaatcatg attttcacat ctacaccaga ggcagttgcg atttttaaag
    13381 cagcaatgac actttcatca ggaacaaggt aaggtgtctg tatccaaaca cgttttttag
    13441 cagaagtaat caatttgata aatgaaagct tgatttgttc cctttcgtta ttcggtccgc
    13501 ttgaaacaag ctggatggat gtatcagcaa gcttagattc atctcgatct gcttttttaa
    13561 agaaataatt caaatgatag ccgacctttt tttcttcagg taccgagacg ttccagtctg
    13621 ttaagaagcg aagctggagc aaagaagaag cggcaccgaa aatccgtata tgcgtatcgc
    13681 gccaatagcc gaattttttt gttgtattta catattgatt ggcaatattg aaaccaccgg
    13741 tataactaat ctttccatcg atcacaacga tttttcggtg atcatggtaa ttcaatcgga
    13801 aacgaagtaa tgccctttgt gaggtaacaa atgtatggac atgtccacca tttttgatta
    13861 gacgattgaa atcttttgct tttgtgccat gagagccaaa tgcatcatat aatattcgaa
    13921 cttccacgcc ttctgcggct ttttcttcta aaacatgtaa gacttgctgg ccgatattat
    13981 ctgtcacaaa tgcgtaatat tcgatatgga tcgaatgttt ggcttttttt agatcttgaa
    14041 gcagtgaatc caatttctct tgtccgtctg tgagaagagt gacagaattc attcttgtca
    14101 gcggcatacg atttaatgaa gagaagaagt caacaaattg ctgtttgtct ttatcgccca
    14161 tgtcaggatc gtaatgttca atggtatctc ctctaaaaga ctgaaagttt tctaattctt
    14221 tcaagtcact ttgtcggaga tagaattttt tcttatccgt taatccacgt ccgaaaaata
    14281 aatataatac aaagcccacc ccaggaaggg caaacaatac taagagccat gcccaaatgg
    14341 ctgctacatc tcggggtttg atcaaaatag ccaccaaagc aataagtgca tttaatagat
    14401 aaagggcggt tataatacta gataccacaa aaatgttcct ccttacatac aataacatta
    14461 gtatagcatg atagaagaaa gaagcctacc aaggtgaata tacttttcac tcctttcatg
    14521 aaaatgtagg taaatcgggc taaagtagtt gctttttgta ggttaataag gtaggatatt
    14581 agtacagttg aatatctcct taggggagta accggcaacg tttgttgcga taatatcaac
    14641 agtaagttaa ccaaatggtt ttctggtatt gtatgaaatg gtgagaccta agacaaatgc
    14701 gtatttgtct taggtctctt ttttttcaga caggactagg gccaagatca aaaaatgggg
    14761 gatgaaattt ggaaaacaag gaacaagcac aacaagcggt ctataaagaa acgatcgact
    14821 cgttgatgca gcaaacgcag agctcaaccg atggattgag caccacgcaa gcgaaggaaa
    14881 aattagaaag agatggcttg aaccagctaa aagaaaagcc gaagaagcca acttggaaat
    14941 tgttcttaga aactttcaaa gatgcaatgg ttatcgtatt gctgattgtc gcactgattc
    15001 agatggtcat gggtgactac atcgaattct tagttatttt tgcagtattg atgttgaatt
    15061 ctataatcag tgttgtccaa acaaaaaaag cagaaggttc tttagaagcg ttgaaaaacc
    15121 tttcagcgcc cgatgctcga gtgattcgtg atggtaagga aaaaacgatt ccggcaaacg
    15181 aacttgtggt aggagatatc gtgttgttag acgcaggcga ttatgtacct gctgatggac
    15241 gtttactaga tgcgggatca ttaaaagtag atgaaggtat gctgacagga gagtcgactt
    15301 ctgcagaaaa agaagtaacg gatatcacaa gtacggtacc aatcggagat cgtacaaata
    15361 tggtattcag tggaacgatc gtaacttacg gacgcggtaa attcttagtg acttcaactg
    15421 ggaataatac ggagatcgga caagttgctg gccttttgga atcaacaact gagcaagtca
    15481 ctccgttaca acgaggtctg gataaattca gtaaaaaact aagtttggct attttggcat
    15541 tgtctttatt gattttaggt atccaactgt ttcgtattta tcttggagaa ggtacaggag
    15601 atatgactgc agatatcgtc agcgcagtga tgtttgccgt agccgtagcc gtagctgcta
    15661 ttccagaagc attacagtct atcgtaacaa tcgtgttatc tttgggaacg aataaaatgg
    15721 caaaacgtca tgccattatt cggaagcttc cagcagttga aacacttggt tcgacaagta
    15781 tcatctgtac agataagact ggtacattga cacaaaacaa aatgacagtt gttgactact
    15841 ttttaggtaa tggcgatact ggggatttca caaatgaccc ttcaaaatgg acagctgacg
    15901 aacgtcgctt gatcgaaatc agtgttttag cgaatgatgc atcgatcagt gaagacggta
    15961 ctaaattggg cgaccctacg gaagtagcgt ttatcgactt tagtgaaaaa ttaaaccagc
    16021 cttatcagga aatccgaaac aactacccaa gacaagcaga acttcctttt gactcagatc
    16081 gaaaattaat gtctactgga cacacaattg ataacaaaaa ttacttgttt gttaaaggcg
    16141 gaccagatat cgtcttccaa cgcagtaaaa aagtattgct aaatggtgaa gtcgttccga
    16201 tgacggatga attgatgaaa aaattccaag agcaaaatga agctttttca acacgcgcat
    16261 tacgtgtact agcttttgct taccgtccac ttgataattt tgatttatca tttgaagatg
    16321 aagacgattt gatccttgtt ggtttgcttg ctatgatcga tcctccacgt gctgaagtga
    16381 ctcaggcggt aacagaagca agaagtgcag gaatcaaaac aatcatgatt actggtgacc
    16441 acaaaacaac agctgttgct atcgcaaaac aaatcgggat ttttgaagaa ggaaacctgg
    16501 ctttgaccgg gacggaacta gatgaattga cagaagatca actaaacgaa gttttagaaa
    16561 aagtcactgt ttatgcacgt gtttcacctg agaataaaat tcgtatcgtt cgtgcttggc
    16621 aaaataaagg tcatatctca gctatgacag gtgatggtgt aaatgacgca ccagcattga
    16681 aacaagcaga catcggaatt gctatgggaa cgggtacaga tgtggcaaaa gatgcagcag
    16741 cgatggtatt gacggatgat aactttgctt ctattgtcag cgcagtagaa gtaggacgta
    16801 atgtgtttga taatatcaag aaagctattt cttatctatt tgcaggaaat ttaggtgcga
    16861 tcattgcgat catctttgcc ttagttgctg actggtccaa tccatttaca gcattacaac
    16921 tgttgttcat caatttagtc aatgattcac tgccagcaat tgcattaggt acagaaaaag
    16981 ctgaacctgc tacgatgaac cgcccgccaa gagatccaaa ttcaggaatc tttacggaca
    17041 aaacattgat ttctgtaacg tatcgtggtg tgctgattgg gattgctgtt atctttgctc
    17101 aatggcttgg catgcagcat tcacctgaat tcggtgtagc catgtcattt tcaacattga
    17161 tttggtgtcg gacattgcaa acattcccag cacgttcaaa cacacaaaca gctatccaag
    17221 cagggttctt ctctaacaga agtgtcttac tagctgtagt tgtatgtagc gcgctttact
    17281 gcttaacaat gatcccagga ctgaaagaag tcttctctat cccatcagca tttggattga
    17341 cagaagtctt tacatgtatg ggaatcgcac ttgtgacaat tgttttgatg gaaatcacta
    17401 aattgatcat tgtacgagta caaggaaata aataaaacga atcaacgagg ttgtgagcct
    17461 gccgtttaat tctgagtcac aaggtgcaat ttcaacaaac agcttctcat gtttgttgaa
    17521 tattgtgact tgtgaccgaa gagttggcag gagaacaccg tttaaggaag aagttgtaaa
    17581 atcagcattt tgagctaata ctgagggtca tctgattgga cactgtttat tcggaaagag
    17641 ggactttgac acgactttgg tcacagtccc tttttttatt tatgatagac ggaaagccaa
    17701 tcattttatt attcatcaaa agagatagaa tagataaaag aggagaatga tttattccga
    17761 aaagtgaaaa catataacaa aaaattagag gaaatcaaat gaatgaaaaa gaatgggatg
    17821 aatttgctga agaatattat gaaatccagc aagaatcgca agtaactatt gctgaagatg
    17881 taaaaaatta tctgaaaacg gagaaagtcc tgcctgctga aacagcagca gacgttgctg
    17941 gaggatctgg cagatttctt tccttagcaa aagaaattaa tcgctatgat ttgatcgatt
    18001 tttcttcagg aatgctagaa aatgcaaaaa aagaagcaga aaaaaatgag ttgccaaatg
    18061 tttcctttat caaacagtcg ttagaagaat ttatccaatc aaatgagaca tatgaaatgg
    18121 tttttacagc agcaaatcca gcattggtac atcttattca attagaaaaa ttgatgaaaa
    18181 agtcaagcaa atggtgcgtg ataatcagag tagtggaatc aatcgatgat gttttttatc
    18241 ctatcgaaaa gcaactagga atgatagaag aagatcctaa tacatcgcca gttgtaatgg
    18301 atcaatttga aacatactta attgatgaag gattcaaagt gaagaaaaaa gattttactt
    18361 attttacaca ggaatcaatt actgaagaat tgatgaagct atactatgac gcgtacgcaa
    18421 aagatcctgt tgtgaccagg tacattcgca aactattcag tgaaaaacga gaaatcctta
    18481 gtacgactaa gctgacctat agactgctcc tttggtccgc agataaaaaa agaacctttc
    18541 acgactcgtg aagggttctt tttatgattt tattatattt tgtagtaacg aatatcattt
    18601 tcgatctttg taatcgaaaa aggtacatct gaagtatatt ctgcacattc tccgtgttca
    18661 ggaagcgtct cactgaaaat cgtttcatat tcgtcaacag tgatccgtgt tcgagaatct
    18721 agcatctctt gatgagattg tgcgaagaga tattcttgat agttttcttc cagataacct
    18781 gtaaaaaatt cacttactgc accagaaccg tagctgaata gaccgatgcg atctcctggc
    18841 tgtagtgatt tcgaattttc cagtagagaa gttagcccca ggtataatga accagtgtaa
    18901 agattaccga ttcgtcggct gtaacggatg ctttcttcat agcgagccat aagacgttcc
    18961 tgattttctt cgtctgtttg gtctaatacg ctttgcaatg ccttttttcc catcttagta
    19021 tacggaatat ggaaagcaat cgcctgataa tcttcgagtc ctcgacccga caattcttta
    19081 tgtcgattcc aaactttttg gaatgattcg atatacgtag aattagataa aggaccatca
    19141 acaacaggaa attcgctata atctggacgc cagaaatcat agatatcttc tgtcagaaat
    19201 acgctgtcgt cttcaatcga taaaatacgc gggttttgag tgatcatcat cgcaacagca
    19261 ccgacacctt gcgtcacttc accaccgctt gccaagccgt aacgagcaat atcacttgct
    19321 atgactagta cttttcgttc tggatgattt ttgacatatt ctttcgccat gtgcaaagct
    19381 gcggtgccac cgtagcaagc ctcttttact tcaaaagaac gagcaaaaga ttggattttc
    19441 agtaaatggt ggataattac cgcactcgct tttgaatgat caatcccgga ttctgttccg
    19501 acgatgacca tgtcgattag ctcacggtct ttttctgtta cgattttgct ggcagcattt
    19561 gctcctagtg taatgatgtc ttcatttgca cgattgactg ccatttggtc ttgaccaatc
    19621 cctatatggt attttgcagg atcatcccca cggctttctg ccaactctgt catatctaaa
    19681 tataaattag gaataaaaaa ggaaagacga tcaatcccta ttttcatttc aacacctctt
    19741 tacttatgat aaaaaactta ctttactaag gtatcataaa aagattaaaa gaaatataaa
    19801 aaagagaata tttaaggatt gttaaaattt aatcttagaa aaaaataact ggaacaagag
    19861 ctatttgttt ttacagcaaa gaatggtata tttttgtagg aggtggctta cttgaaagaa
    19921 gtcgttatga tagatgctgc aagaacgccg ataggaaagt atcgcggaag tttaagtcca
    19981 tttactgcag ttgaattagg cacacttgtg actaaaggat tattagataa aacaaaactg
    20041 aaaaaagata aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg taatggtcaa
    20101 aatgttgcca gacagattgc tttgaacagc ggtctccctg tagatgtccc agcaatgacg
    20161 atcaatgaag tttgcggatc tggtatgaaa gcagtgatct tagcacgcca gctgatccaa
    20221 ttaggtgaag cagaacttgt gatagccggc ggaacagaga gtatgtctca agcacctatg
    20281 ctgaaacagt atcagtcaga aacaaatgaa tatggtgaac caatttccag tatggtcaac
    20341 gacggattga ctgacgcatt ttcaaatgca catatgggat taaccgcaga gaatgttgca
    20401 acacaatttt ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc ccagttgaaa
    20461 gcagcacatg ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt caagatttct
    20521 gatgaagacg tgttatctga ggatgaagca gttcgtggaa atagtacatt ggaaaaactg
    20581 ggcacgttac gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa tgcttccccg
    20641 ttgaatgacg gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga aaataataat
    20701 ctgccttatt tagcaaccat caaagaagta gcggaggtcg gtattgaccc aagtatcatg
    20761 ggaatcgctc caatcaaagc cattcaaaaa ttgacagata gatcaggaat gaatttatca
    20821 acaatcgatc tttttgagat caatgaagca tttgcagctt cttctatcgt agttagccaa
    20881 gaactgcagt tagatgaaga aaaggtcaat atatatggag gagcaatcgc attaggccat
    20941 ccaattggtg caagcggtgc acgtatcttg actacattag cttacggatt gcttcgtgaa
    21001 cagaagagat acggtattgc ttcattatgt attggtggag gtttaggctt ggcagtcttg
    21061 ttagaagcga atatggagca aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt
    21121 acgccatctg aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg
    21181 ttgatttttc aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa
    21241 gtgagtgaag tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa
    21301 aaatggattc cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca
    21361 aaaatctgtg gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt
    21421 ctatcaggaa aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag
    21481 ctgattcttt gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa
    21541 gatatctcta ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta
    21601 gtggatgtaa aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca
    21661 aacaagttac gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt
    21721 gctacagaat cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac
    21781 aaagaaatcg gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt
    21841 gacccttacc gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg
    21901 gcagctacag gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga
    21961 aatggattat accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa
    22021 ctaacggtgc ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca
    22081 aaagcatctt tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct
    22141 gcagtagggt tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa
    22201 aaaggccaca tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag
    22261 gaaatcgagc aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct
    22321 atacaaatat tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag
    22381 caagatttac agttatttta tttactgcag atcttgcttt tttctctatc agaaaatatg
    22441 tttattatta gaatttttta tagttaaggt taggcatctt aagaaatcag gcaactccaa
    22501 gatatcttca ggtagaagag aagtcgccta acattgtagg atcataggtg atttgttgga
    22561 caggtcaagc tgatatttga gcctgatgtt agaaggaatt tctttttact tgctgtagaa
    22621 attattatat gactaaaaag gctgggattt taaatcccag ccttttatga caaatagaat
    22681 ttttatcgat cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat caaagtcaat
    22741 ttgactttgt atttccgttc gagtgctttt tcgataacga actcattttc agtagtcata
    22801 gaaatagttg ctaatttacg aggttcatca gcattttttt cattaataac tacttcatgt
    22861 tcattttgtt ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa
    22921 cttaaagcgg cattcgtatc agttgagcgt gtattttcag ttgtgtccgc ttttggtttt
    22981 tccgtttttt cttctggcac actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc
    23041 gcagttggtt catcgttttt caatcgttga tcattccagt aagacacgat ttcaataaga
    23101 agattgtcac ggaatcgttc gaaaatcccg ttttctcctg aacgaattct ctttaataca
    23161 gtattgaagt tgtcatcgat tggcacgttg atccgtgtat cttcatttgt tttcccagct
    23221 aatccgatcg ttaagatttg acggtttttg ggatcaagca tgacttgtaa cggcaaacca
    23281 taacgtcgca agctctcttc ttctagagaa cggaataatt gtcctcttac accatccaat
    23341 gaaggacgga attgatttaa taatttttgt ttctgttttt tcttcatatg ttctctcctt
    23401 cgctcatacc ctttcgatta taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa
    23461 aacttgcgta tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga
    23521 aaaataaaaa atggaacgga ttatgtatat atacataatc cgttccattc tttctatttt
    23581 ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg ttcgtgccag
    23641 ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt
    23701 gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg
    23761 gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat tggatccata
    23821 aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc cgactacacc
    23881 atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa ataattcagt
    23941 attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag
    24001 cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat
    24061 ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga ggatcatatc
    24121 atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa ggaaaacttg
    24181 attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt ggggtaagaa
    24241 attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa atgctcgcca
    24301 tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg gccagtggat
    24361 caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa aagaagacat
    24421 cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata tctcttctct
    24481 aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt atccttgggc
    24541 agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa cagcgacatc
    24601 cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac catttgatag
    24661 acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg ttcaactata
    24721 agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga aatttttgtt
    24781 taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac taagacagaa
    24841 gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat tgacagagaa
    24901 actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata tattcgtgat
    24961 tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg acaactagca
    25021 gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt ggaagcaagt
    25081 gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc acctagtgca
    25141 gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt attgaaagtc
    25201 aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat cgacaaccgc
    25261 ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga agcattcgct
    25321 gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa
    25381 aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa
    25441 aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga gacagaagaa
    25501 tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga aaaaggtcgg
    25561 ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct
    25621 tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt aaaagaagta
    25681 caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa cgggatcgaa
    25741 ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt gaataatccg
    25801 gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg tttataaaaa
    25861 tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt gtcaagagaa
    25921 ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa gaacactttt
    25981 gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactccttc ttatttcttg
    26041 gagttaaacg cttctgtccc agcctctttt tatctaataa aattttaaga ccatttacta
    26101 attatcgatt ttttctgccg catttttagg cacttcagaa gcctttattt cttcccagct
    26161 taatacacct ttacgaggat tgactttgag tttaagatac gcattcatct ttaatggatg
    26221 ttctctttct tcgcgaagcg tcacctgttt tttttcacca tctttattat aagccgcttg
    26281 cttgtaggta taagtcgtga atttctctcc gttatctgct tgggtagctg acatttcgcc
    26341 attcgtcgtg atttttgtat aataagcttc gccgccgtaa aaataatgat aagctgcaaa
    26401 acttccgccg agaaatatgc ctaaaacgac aagtacgcca attaattttt tcatgtactt
    26461 cacctctttc cttattatta acgaaataga agatttcgtc tattgaaagt tgttggcaac
    26521 agctgaattt taaacttttc ctcattttgt tcttattgct tcaaaagaaa gttaaggact
    26581 atcttgaagt ttttctcaaa aaacacattt ttttatttat aaaaggtact tttttcgcgt
    26641 ataagacaga cgagtgctct tagttgactt tgaccaatat tgacgtataa taagcttagt
    26701 tcgaatctta caaaaagtaa gtcggacgta ttctttttga tttagtcaaa aaaagactat
    26761 aataaaaagg tgagagctga aatttttcag tgatctatat tatttaggag gtttgtaaat
    26821 tatggcaaaa gaacattatg acagaagtaa accacacgtt aacattggta cgattggaca
    26881 cgttgaccat gggaaaacta ctttaactgc tgcgatcact acagtattag gcaaaaaagg
    26941 cctagcaaat cctcaagact atgctagtat tgatgcagct ccagaagaac gtgaacgtgg
    27001 gattacgatc aataccgcac acgtagaata tgaaacagaa aaacgccact acgcgcatat
    27061 tgatgcacca ggacacgcgg actatgtgaa aaacatgatt acaggggcag cacaaatgga
    27121 tggtgcaatc ttagttgttt ctgcaactga cggtccgatg cctcaaacac gtgaacacat
    27181 tttattgtca cgccaagttg gtgtaaaata cctgattgtt ttcttgaaca aagttgattt
    27241 agtcgatgat gaagaattga tcgatttggt agaaatggaa gttcgcgagt tattgagcga
    27301 atatggtttc ccaggcgatg acactcctgt gatcaaaggt tccgcattaa aagcattgca
    27361 aggcgatcca gatgctgaag ctgctattat ggaattgatg gatacagtag atgaatatat
    27421 cccaacacca gaacgtgata cagataaacc attactattg ccagtggaag acgtcttctc
    27481 aattacaggt cgaggaactg ttgcctcagg tcgtattgat cgtggtgctg ttcgtgtcgg
    27541 tgatgaggta gagatcgtag ggatcaaacc tgaaacacaa aaagcagttg taacaggtgt
    27601 agaaatgttc cgtaaaacgt tagattacgg ggaagctggg gataacgtag gcgtgttgtt
    27661 acgggggatc caacgtgacg atatcgaacg tggacaagta cttgctaaac caggttccat
    27721 tactccacat acaaaattca aagcagaagt gtacgtgttg acaaaagaag aaggtggacg
    27781 tcatactcca ttcttcaaca actatcgtcc acagttctac ttccgcacaa ctgatgttac
    27841 aggaacaatc acattgccag aagatacaga aatggtcatg cctggtgaca acgtgacgat
    27901 tgatgttgac ttgatccatc caatcgctgt tgaaaacgga acgacattct caattcgtga
    27961 aggcggacgg acagtaggtt caggtatcgt tacagagatc gaagcataag aaacgcgact
    28021 cgaatatttt ggtaatgaaa aatgtttaaa ataaaagagc ggtccaaaca ggatttctgt
    28081 ttggaccgct ctttgttctt caattgtata agaagagatt gtagaagcat gaactttcgt
    28141 tttacttcag tctcttttat tcatcatgag agtgttcatc tatcggtatg cagtttttaa
    28201 tactttcttc gtatccattt tttcaaacca cttattctac cttgtgtctg ctcaactggc
    28261 gcattatcaa taatcagcaa agcaatcata acatatgcaa tccaactatc tctagaatat
    28321 agagtataac gtgagaccca gtttgtagcg tacttgcttt tatattctct taatccatgg
    28381 aaagaataaa aatgagaacc aaactcgtaa accaagtatg caatcctttc ctgtaaaaaa
    28441 ctctttctgg aagttccgac atttgaaaga ggggccatcc ctaaattgaa ccattggata
    28501 tgttcttctt tcatataggc aaacaaatgc aagaacaaga aatccatact gccagaaggt
    28561 gcttttttag aatcatatcg catcagatca atcgttccta ctttattgtt cgtgtaagta
    28621 ggcatgatcg ttgcaaaagc gacaatttct tcttgggtat ttttgacaac tgcaataggc
    28681 gctctttgta gataatcttc agagaaaaag cctaaagaaa accctttttc ctttcgtgaa
    28741 cccaaccaat tatcagagat atttttgaaa gtactcattt gctcagtaga aaatggtggt
    28801 tgtaagacat caaatgtaaa tccttctcgt tcgatccgat tcaagacagc acgagtgccc
    28861 ttcatttttt tccctgaagt tgtaaaacta ttcaggtcta cataagcttc ttcccccatc
    28921 ttaatgaaat cgtagccgaa ttcatgcaaa atcataacaa tctcttcgct tgtttcgtag
    28981 aaaactggta aatagcatag tcgatctgtt tcttcgataa aagcttcgat tgcttctgga
    29041 aaatcttctt tcttaccaga aggatcaccc attacaatac atttattatt gaagcaagcg
    29101 aattggagaa gaacagttgg ttcaccgtct ttttcatagg caaacatccg cttatctttt
    29161 aagaagatca attgactatc ggagtttcct ccataagttg taaggatctt cagggccttt
    29221 tcttcattaa aggcttcgcc aatctgtttc ttttctcctt gaaggaaatg aacaaataga
    29281 acgatcatga aactaacagc gatgatggcc aacaatcccg aaaaccaaat cttttcagaa
    29341 ggaaataaga aaaaggaaat aaaatggtga cgccgatgag ggaaatctgg cagattgtat
    29401 accccaataa cgatgtaaag caaggacagt gcaccaataa tgattccatc gatcgtacgc
    29461 cactcccatg aatagatcaa ttgttcccga aataattcgt ttttagaagc aagaatgatc
    29521 agaagcagaa tagacaagaa aaccaccggt gtgaaactaa aatcacttaa taaaacataa
    29581 agtaaagcta gaacaatcaa gaagattgta ggcaaatatg ctcgtttcac acgtgctgcg
    29641 atccctctgc ccataatgat taaaagaaat cccaatagta tactaggaaa ttggataata
    29701 aaatgaaatt tcaatgggtt caaactatga agccagcgaa actctgtaaa agcttgcggg
    29761 atagtggcag aaagtactag catgattcca gaaaagtata ataagacaac cacgatttta
    29821 tgcgcaattt ctgttgctaa ttgtttaggg ataccagaat aacgctgatc aaaagtggaa
    29881 ccgatatttt tgaagaaaaa gacgattcca atcaaaaacg gaatgatgta gtagaacagg
    29941 cgatagagca agatccacac aacgactatt tctcttggca caccaatagc ggacaacccg
    30001 ataatcatca ttacatcgaa actcccaatt tctcctggaa tcatagacac gattcctatc
    30061 actgaagcag caatgaataa tggaattgtt tgccacagat caatccggat ttccattaaa
    30121 taaccaacag aaaggaaact aaacaggaca ccggtccatt ccaacaatga aactagcaat
    30181 agctgtcctt gagttttaag tgaggtacca ccaaggaatc ctttcttttt gaaagtagta
    30241 aataaaaaga cgacaggaaa atatagaccg ccgccgatca accatatcca atattgcttc
    30301 aaaaaaggag caactggcgt gaagactaca agtaaaaaag aaagcagact gtaaatagaa
    30361 agtccagcca tcaaaaacaa gaaaactttc gataatgctt ggatcacgtt tctgctctct
    30421 ttcttttgtc catatagttc agagcgaagc cccacactaa caaacccgcc gaaaccggca
    30481 atattgttga tcgtattgat cagccagctt gtctcaaaca ggtaacgagg attctgcttt
    30541 tgttcaagca tccgattcaa aataatatca taaccaacca taggtaacac agagataaga
    30601 ccaatcaata gcattagtcc gcttttccat acaggtatag tggcaaacgt ttctcctaat
    30661 tgctggatag atagagtttt accgatggac atcaattcac cgacaataat gacaatgaca
    30721 gaaatcaaaa agattgtttt gaacagtcct aggtggtttt tcagccattg tatggtattt
    30781 tttaacaaat aaatcacctt ctattcctaa tagttatgtt tcagaaagaa attgaagaac
    30841 ttctcgattg aagcgttcag gatcttttct agctaattca tgtccttgtt ctttcacaag
    30901 cacaaaggaa gcttttggta tagttttagc tatatacaaa gaatgtttta gcttgattac
    30961 atcttttttt cccacgatga tcaaagtggg ggagttgatt ttttttaaat cattttctgt
    31021 aagcccgatg tcatgcagca aaagtttgat aactaaaaga tttttgcgaa gacttgggcg
    31081 aaataaagag agtaaccata cccatgcata atgaatatta ctgatgactc tggcagaaaa
    31141 acgaacgcct ttaacaagcg tgtttccaga atttaaaatc aatcgatgaa cttttttagg
    31201 gaagctgctg gcaaatacca gtgctagatt tgctccatca ctaaatccaa gaaaatctgc
    31261 ctgatcgatt ttttccagca acatgatcgt attcagatcc tcggccatta actgaaaatt
    31321 caacatagat gcttcgtttg tcgaacgacc atgtcctcgg ctatctacta gatacacggt
    31381 atagtagcgt tcgagtacag ggacctgttc tgaaaaaaag cggccgctgc cgtcattgcc
    31441 atgcagtaaa aagagaggga agccttgacc gctcttttca tagtaaattt cgctcccatc
    31501 tggcattttt gcatatttct tttctttttt cacataatca cctactgtgt aaagtataac
    31561 gattatatca gtcattgggc aattgttttt actgaaaaac aacgatcatt ttcgtaagat
    31621 gtcaaaaaat acaggaaaat tcattttttc ttaaggcgta cacagaaatc aaggaagaaa
    31681 tagccaagaa gataaagaaa tagtaagata aaaaaagatg tcaaaataac taggtgatga
    31741 aatgaagcga aaacgattat ctattatccg tattcttttt tacatgatca ttctgacggt
    31801 tattggtgcg gtgttgtttt taggaggaag aacttatcgt tcggtaaaac gagtggaaag
    31861 ctatcaaata gaaataacaa cagctgcaaa aaattatcat atggaaaact acgagaattt
    31921 gatcaaggcg ataatattga ccgaatcaaa aggaaaaggg acagatctca tgcagagctc
    31981 ggaaagtctg catggagaag ctgagatcat tgataatcca gctgacagta ttgatcaagg
    32041 tgtcaaatat ttggcggaaa tgatagtaga agcaaagaaa caaggatgcg atttatggac
    32101 agctgtccaa gcatataatt ttgggaaaga ttatattgcc tatgtaaaaa atcatggcgg
    32161 agaaaacaca gtagaattag cagaagcgta ttctaaagat gtgctgagcc cacttttagg
    32221 aaatgaggaa gggaaacaat accgatattg gcggatccag tccttgcttt acaatggcgg
    32281 ctatctctat cataatggag gtaacatgtt ttatcctgat attgtcaaaa tgaatgaaaa
    32341 aataatagag acctatgaaa aagtctttaa gtaaaatagc aggaaatgtt caatcatgaa
    32401 taaaattaaa tgaaagaagg agtgcgcaaa tagtggaaaa aaggcaaaaa atggaaaatc
    32461 aagaagtggg gtacacaacc aaagactgga tgttacggtt tgtgaaggga atgtttatcg
    32521 gttcaggatt tatcttgcca ggagtcagcg gtggtgcatt agcagctgtc tttggcatgt
    32581 atgagcggct gatttctttt ttagcccacc ttacaaaaaa tttcaaagaa aatgttttgt
    32641 tttttctgcc tgttggtcta ggcggagtga caggcatctt tctactttct tttttagtca
    32701 gttttttatt aggtgcgtat gaaacaacga tattatggtt ttttgtcgga tgtatcgctg
    32761 gaactgttcc tgcgttatgg aaagaagcag ggaaaaaagg aagagatact tctgatgtga
    32821 tcatcatggt tgttactttt gttctggctt atttgttttt attatacggc gctcaattat
    32881 ttgacgggca agtcgatcag aattttggaa catggctgat tgccggcgga ttgattggtt
    32941 tgggtatgat cgtcccagga ttgagccctt ctaatttttt ggtgtatatg ggattgtata
    33001 aagcgatggc tgacggattt aaagaagtac gacttgaagt gattgtgccg atcggaattg
    33061 gtgggattct ttgtgttctt ggattgtcaa aaatcatgga ttacattttc tcaaaggcat
    33121 atagcaagct attccatttc attttaggtg tagtttttgc ttcaacgatt atgatcattc
    33181 ctaccgatta cgcgggattg ggagttgctg gggtactagc ttgtcctgtt ctttttatag
    33241 ccggtacagc actaggttgg tggatgagcc gtttggagga acaatataag taaagataga
    33301 ttgataataa aaacagcaca cgggtgattc aaacaaaaag gttggcatct tttttgtaaa
    33361 atcattcgtg tgtttttcta taaattttat aaaaacaagt tgtttttaat cttggaacac
    33421 gctagactta aacacgtgat tatttttgaa agttggcgga aaatggagaa aaagaaaatg
    33481 aatggactta cacagcaaga ggtagttcag aaaatggctt ctggccagca aaatgactac
    33541 caggaagatg catcaaaaag tacaaaacaa atattcagcg ataatatatt gacgttattc
    33601 aattttctga actttggtat tgggatttgt ctgttatttg taggtgcgta ttccaacatg
    33661 gcgtatttag caattattgt cgtcaatatc gttattggaa tttatcaaga aatacatgca
    33721 agaaatcttg tacggaaatt atcgattgtt tcccaatcag aagtactagt gatccgggac
    33781 ggtaaagaac aatcgatttc tactaaagag ctggtattag gagatttggt aaaaatcgga
    33841 gcaggagaac agataccagc cgatttacag gttatatctg gacgggcaga agcaaatgaa
    33901 gctcttttga caggcgaatc tgatttgatt gtcaaagaaa ctggagctga attgctttct
    33961 ggaagctttt tgacaagcgg ttctgtcatg gctgaagtta tccgagtagg tgcagataat
    34021 tatgctgtcc gcttgactag cgaggcaaag actcacaaag ctattcgttc tgaacttgta
    34081 gattcgattc gcaaagtatc caaattcact agtttcgtga ttattccttt ggggatcata
    34141 ctatttttgg aagcactgtt catccgcgat gcttctatca aaatttctgt tattgcatct
    34201 gcagcagctt tgttaggcat gcttccaaag ggtttggtat tgctaataag tattgcatta
    34261 acgacagggg taaccaaact ggcaaaaaaa cgaatccttg ttcaagacat gtattcaatt
    34321 gaaacgctgg cccatgtcga tacattatgc ttggataaaa cagggaccat tactgaaggg
    34381 aaaatgagta tccagcgggt agaagcacta catccgctgt acgagaaagc catcccagaa
    34441 attatgggga cgtatctggc agaaagcagt gataacaaca tcactatgcg ggctatgaga
    34501 gattattttg agctttctaa tcggtatgat gtgacaaaca aagtcgcatt ttcttctgat
    34561 cgcaaatggg gcgcgatgga atttccagaa ctgggagtcg tgtacgtagg agcgcctgaa
    34621 cgtttggtgg aagaagatcg gcttccggac agtctaaaaa cagcccaagc gaatggctat
    34681 cgcgtactta tgttggggat cgctccaaat cagcaattga acgaagaaaa accagcattt
    34741 gttgagccgg ttgctctgtt tgaaatcgat gatccaatcc gaaaaaacgc tcaagaaaca
    34801 ctagcttatc ttcatgagga aggtgtggat ctgaaagtga tttctggaga caatcctttt
    34861 actgtctcca atatcgctag acgtgcagga ttaccgaatt atgatgcgta tgtcgatctt
    34921 tctcaaatta ctgaagaaat ggaagtgcga gaagctgctc atcgctatac ggtttttgga
    34981 cgagtgagtc cgcagcaaaa gaaattgctg gtaaatgaat tgaaagaaag cggcagaacg
    35041 gttgcaatga caggcgacgg tgtgaatgat gttttggcgt taagagaagc agattgcagc
    35101 attgctatgg cagaaggtga tggagcaaca cgtcagattg cgaatctggt attgttggac
    35161 tctgatttta ctacattgcc agaagtcctg tttgaaggac gccgagtggt caacaatgtg
    35221 acgaaagtct caggcatctt ttttatcaaa acgatttatt catttatttt atcgattata
    35281 tgtgccgtta cagcaattgg atttccgttt atccctatcc aaatcacgct gattgattta
    35341 gcgattgaag ggtatccttc cttcttttta tcttttgaac aagataaaag aaaaatcact
    35401 taccgttatt tgcctacagc acttattaat gctttaccaa atgccttgct tgtagtagtg
    35461 aatatcattg cggtgtatct acttggaaaa acattcgcat ggggaaatgc tgaaactact
    35521 actttgatgt attacttgct gattgggatc agttgcatgg cagttgtaaa agcttgttat
    35581 cccttcaacc cattgcgcat cttcctagca gtaacgacga tcgtagggat atatgtagct
    35641 gcaatgctgt tccatggaat tttggaagta aacttagggt tgggagagag cgtaggatac
    35701 ttctttgtat tcatgctcgt aaatattgtt cttcgagtat tgtactggaa ggctgatatt
    35761 caaaatcagt tactgaaaag agtagcaaat tgatgcttaa tgagatagaa atgtgttata
    35821 cttgaaaaag caatgaaata tgatacaatc aaacatgtat aattgtgtcc tttaaaatcg
    35881 cactgatttc agttagtgcg attttttacc ggttattctc ctgaaatatc ttctgttaaa
    35941 cccaaaagat atcaatagag cagggggtga aaaaatggct caacggattc ctcaagaggt
    36001 tatcgaaaca gtacgcagtc aaacgaatat cgttgaggtg attggacaat atgtccagtt
    36061 gaaaaagtct ggtaaaaatt acttggggct gtgtcctttt catgaagaac gtacaccgtc
    36121 tttttctgtt gcagaagaca agcagatttt tcattgcttt ggttgtggta aaggcggaaa
    36181 cgtgtttact tttcttcaag aactagaagg tctaagtttt ccagaagcag tggtaaaagt
    36241 ggcagacttc gaacagatac cgttagaaga tcaatggcgt cagcgtacta tagctgtcca
    36301 aaatcctgaa tctgctacgg ggaaactgat tgctgctcat gaaaaagcag cggaaatcta
    36361 tcatcacatg ctattgcata caaaagctgg acagccagct ttagaatatt tgcaaagtcg
    36421 tgggttgtct ttagaattaa ttgaagaatt caacataggt tttgcaccta atgagcgttc
    36481 ttttcttcag caagtattca agaatgaatc aatttcaaat gaattgttag aacgctctgg
    36541 attgtttgtc acgcatgatg atggccgtat gtctgatcgt ttttatcaaa gagtgatgtt
    36601 tccacttcgt aattctcaag gccagacgat cggtttttca ggacgctggc ttgcacctga
    36661 aaaagggcag gaaaaagatc agcccaaata cttgaatagt ccagaaacag aactgttcaa
    36721 taaaagacaa gttttattta atcttgataa agcaagaagc gatatccgga aaaacggaga
    36781 aattttgttg ttcgaagggt ttatggatgt gattgctgca tggcaggctg gtatcaaaac
    36841 tggattagct tctatgggga caagtctaac agctcaacag atccaacaaa tggaaaagct
    36901 gacgaaagaa ttggtctttt gctatgacgg agacaacgca ggttttgaag caaccaatcg
    36961 agggattgaa ttgcttcggc aaaacagtcg attagcactt tctgtcgtag tcgttccaga
    37021 aaagcttgat cctgatgaat atctccgtaa gtatggagaa gcatctttcc aagaattagt
    37081 ggctcatggg cgcgaaacag tctttacttt taaatcacgt tatttaaaac aagggaaaaa
    37141 tttagataat gaaaaagaca agatcgaata cctcgaagaa ttactagttg aacttagccg
    37201 agttgtttca ccaatcgaac aagatatgta tctatctcaa ctgtcaacag agtttcagat
    37261 cggcagagag acgatacaaa aacaactgcg cgatcttcga aggacaaatc agcaaaatcg
    37321 tcaagaacct caggaaagtc aacacactca ggttacgaga caagaaactg cacggaaaaa
    37381 gagacctttg acgcaagtag aaaaggcaga gcagattcta ttatatcgtg catttaaaga
    37441 agtttctgtc cgtaatattt taaaagaacg agaatttcag tttattcatg atgcatatgc
    37501 agaagtttat tttttattcg atgcatatgt ctcacaacat tatgaattca accttgcaga
    37561 gtttttagac tttttgcaag atgaaaattt aaggcggttg gtggtggaaa tcgaatattt
    37621 accggtggca gaagaaagtt cgccacgaga aatccaagac ttgctagatg tgatcagcaa
    37681 atctggctta gctgatgaaa taacattaaa aaaacaaatg cagcaagaag ccagacgaac
    37741 tggaaacaaa cagcttgagc ttgaattgac gattgaaatc atcaatttaa cgaaacagtt
    37801 aaaacaagcc aaatagctac tcaagggggg ccttctttta tggcaaatgg aacagataaa
    37861 aaaacgtatg aagcagcagt agcagctttc atcaaagaaa acaaacccaa acgacaagtt
    37921 gtatatgatg atttatccaa tcagcttgct acaccattca ctttgaatgc agatgaaatg
    37981 gacaaattga tccaaaagat tgaagacgca ggtatcagtg tggtggatga aaatggtgat
    38041 ccatcaattc acagcttgaa gagtgctgag aaaaaagctg aacaagcaaa aacagaagat
    38101 ctttctgcgc caaccggtgt aaaaatcaat gacccggttc gtatgtatct gaaagaaatt
    38161 ggccgtgtct cccttttaac tgcggaagaa gaagtagcgt tagcattgaa aatcgaagaa
    38221 ggcgaccaag aagcgaaaca gcgtctggca gaagcaaacc ttcgtttagt agtaagtatc
    38281 gctaaacgtt atgtaggacg aggcatgcag ttccttgact tgatccaaga aggaaacatg
    38341 ggactgatga aggcagttga aaaatttgac taccgcaaag gatttaagtt ttcaacctat
    38401 gctacatggt ggattcgtca agccatcact cgagcaatcg ctgaccaagc acgtacgatc
    38461 cgtattccag ttcatatggt tgaaacaatt aataaattga tacgtatcca acgtcaattg
    38521 ctgcaagacc ttggaagaga acctacgcca gaagaaatcg gtgcggaaat ggatcttcca
    38581 acagaaaaag tccgagaaat cttgaaaatc gcgcaagaac ctgtttccct tgaaacgcca
    38641 atcggtgaag aagatgactc tcacttaggt gatttcatag aagaccagga agcaacaagt
    38701 ccagcagaac acgcagctta tgagttacta aaagaacaat tggaagatgt actagataca
    38761 ttgactgatc gggaagagaa tgtccttcgc ttacgttttg gtttagatga tggccggacg
    38821 agaacattgg aagaagtagg gaaagtgttt ggtgttactc gggaacgtat tcgtcagatc
    38881 gaggctaaag cattaagaaa attgcgccat ccttctcgtt caaaacaatt aaaagatttc
    38941 ttagaataag cgtggactat tgaccagaag agaaatcagt aaaactgttt ggtttatttt
    39001 aaaagaaaaa aagcttgaga ctacgcagtc tcaagctttt ttttctatag gaaggaaatt
    39061 cattcattat ttttaagtaa atcctaaaaa taagctattg gcgtgacgta tagaatatga
    39121 tagattaaat ggtagcgtaa acctagtaaa ggagccgatc gctaagtgat gaaaaaatgt
    39181 ccaaattgcg gatcgaaaaa aatggagcag aatactatct gtccagactg cggtcatcaa
    39241 ataactgcag aagatcagca aataaaagaa tcaattgaag aaacaaatac agatgcagct
    39301 atgcaggata aatcaactga agatgcagtc tttcctgata cagaattaaa cgatccaatc
    39361 gaatggtcgg aattgaaaga tttacctcta gaatctgtaa tggaattatt cgaaaaagca
    39421 gaaccagaag acgaagaacc acctgctcac gatcaagtaa ctaatataga gaaaaatgaa
    39481 cagaagaaag caactgttca tgagacttcg gaagaatcag gaaagaatca agaagaaacg
    39541 cttgaatcaa aacaaaaaag aagagtagct gaactgaaag aaatcgtcga taatgaggaa
    39601 gaaaattcga tactatccgc ttatatcaaa gcacatcgtg aagatacaaa agaagagcac
    39661 gcgaaagagc tgctcaaaat gatcagtgaa aaaattgcac aggaaaacaa agtagagcca
    39721 gaaaaggaac aagaaactga aaaagactct gatagagaaa acgccacagg taaagaaaca
    39781 gtaaaaataa aagacgtaaa aacggatatc acagaaaaaa ctgaagtatt tactgaaaaa
    39841 caattagaaa aggaaaaaac gaataaactg ccggaagcag agaaaaaaga aatactcgaa
    39901 aacacagaca aaaagtcaac agagcccgat gaaataaata gtgaatccga tgctgaaaat
    39961 caatctgtaa gcaaagaggg tactgatctt gaagcaaaaa tagaaaaaga agagaaccag
    40021 cctaagctgt ttgaagcaga agcgaaatca ataacaatcg tgccagatac tgaaaaaaca
    40081 catcaagaat caaacttaga aaaaacagat ccagataaag cgcaaaagaa aaaatcaaaa
    40141 aaagtacctt atctcgtttt agcagcagta cttctactcg gtggaggaag ctgggcttat
    40201 tatgaccatc atcaaaaagt agaagccgaa gtagcagcag aagcaaaaag acagcaacaa
    40261 atggaagaac ttcatgagaa acttgctgcc ttttatacag atgatcacca tcaatttatt
    40321 cgtgcagata tgattcatca agatttatca aaactaaaaa atgatttatc cagtcttaag
    40381 aatgaaaaag gatattcaga gttagaaaca acttaccaag atatccaatc taagatccga
    40441 gatatccaaa aagtgaatga gtggttcata gcacctgcca tcgtcgatga tcatctagca
    40501 gatgacatca agttgaaagc agataaagag atccaagcaa tcgaaacgga taacacagat
    40561 tttggaaaat tgattcaaca agcacaaaca gaagctaaaa atcaatatgc tgaattgcaa
    40621 acagctaaag aaaaaacagc tatagtcttt aaagacggaa aagtagtgga ttcagcaaca
    40681 cgcgaccaat acaagacggc aaaagaagca gtagaaaaag tgaaaaatac agatctatct
    40741 gctcagttga atgaacaatt gaaacaagta gataagatgc tcactgataa agagaaaaaa
    40801 gaagaagagg aaaagaaaaa agcagaagaa gcgaaaaaag cagctgaaga acaagcaaaa
    40861 caagccgctc aagcagcagc tgcagctcaa gccgctcaac aagctgcggt cgcacaagca
    40921 gcacagcaag aagcggcatc ctcgacccct tcctcttcaa actcagcgaa tcagccaatc
    40981 aaatctgcca gagcaagtga tattgccgat gcatctaatc cagcatggac gtgggcacca
    41041 ggtgtccaaa gcaaagtgat tgctacatgt atccaacgtg gatatatcgt tgaaggaggt
    41101 tacagattag aaaaagccag aatcgaaaat ggggaaggct attataatct atatgccact
    41161 tcaacaaaat ctgcattgat gaaaggcatt ggagaaagtg ctttgccatt ttacatcgta
    41221 accatcaact gtaaaactgg atggttcgga ggaaatggga gcaattaatt ttaggcaaat
    41281 gaaagaggct gtgagcctgc cgtttaacac cgtttattcg aaaaagggga gtatgacaca
    41341 actgttgtca tactcctttt ttcacctttc caaaccaagg ctcagctatt caagtagata
    41401 acattatgtt atgatagcaa agaaatgtat taagaaaacc tttcactata gagggagaaa
    41461 aaaatgaacg atttattagc aactatattt acaggtatta ttattgatga aaatgaaaaa
    41521 aactactttg tccaaaaaaa cggacaaacc tttggcttaa gcaaatcaga aggtgaacac
    41581 aaaatcggtg aagcagttga aggattcggt taccaaaatc aaaaacatga aaatcggatc
    41641 actacacaaa ttcctaaaag ccgtatcggt cattacggtt ttggaatcgt tactgctaca
    41701 cgaaaagatt taggtgcgtt tgtcgatatc ggtcttccag ataaagactt tgtcgtatct
    41761 cttgatgaat tgccgacaat gacagagcta tggcctaaaa aaggggatcg cttgatgatt
    41821 tcccttagag ttgatgcaaa agaccgtatt tggggcagtt tagcagatga aaaaatattc
    41881 aaatctttaa gcaaatatgg aacagaagaa atgaaaaaca aagatgtgat aggaacagca
    41941 taccgcttga aattaacagg tacgtacgtt ttaacggaag atttctatct tgggtttatc
    42001 catccttctg aacgatataa tgaacctcgt ctaggcgagc agataaaagg tcgagtgatt
    42061 ggtgtccgac cagacggtgt actgaatctt tcattgaagc caagagcata tgaagctata
    42121 tcagatgatg cacaaatgat tttaaccatt ttagaacgtt ctgcagatca gcaaatcaac
    42181 tttacagata aatcggatcc agaagaaatc atgaaagctt ttggtatcag caaaggagca
    42241 tttaagcgcg cattaggtaa tcttttgaaa caaggattga ttacacaaga aaacggtgtg
    42301 acaaaactag tcaaaaaatc taattgagaa tcccttgcat gtttttctta actagcttat
    42361 aataatttta attaacatag tgttatatct ttttttattt gtaattatta taaattgttg
    42421 gggttgagta aatggtcatg aatgctattt cggcgatgaa aaaaacaaaa cagcagctac
    42481 atgaagcggg gtttaagctg acaccgcaaa gagaagctac tctgcttgtg cttttggaaa
    42541 atgagaaaga gcatttatct gcagaagaaa tcttcttttt agtgaaaaaa aagagtccgg
    42601 aaattggact tgctactgtt tatcgaaccc ttgaaatctt gacagaattg aaaattgtcg
    42661 ataaagtaag ttttaatgat ggattagccc gttatgattt gagaaaagaa ggcgccaaac
    42721 atttccatca tcatttacta tgcttgaact gcggcacgat cgaggaagta gaagaggatc
    42781 ttttacttga agtggagcaa gtagtagaag aacgttatca ttttttagta aaagatcatc
    42841 ggctaacgtt ccatggaatc tgtcaggaat gctatgaaaa agaaaaaaga aaccagtccg
    42901 tctgagtgtc tagacggctt tttctttgct cagattatgg aaaaagacta tcagaatgaa
    42961 gcggtatctg atatgataga gaggcatgag ggggattatt atgaaagagc aaatcaacga
    43021 ttatctccac tacttgaata ttgaacgggg attgtccgcc aatacacgac aaagctatga
    43081 acgtgatttg gaacagtact tgcattttct acaggagcag aaaattgctt catggcagga
    43141 tgtcgatcgc tttttagtca tccgttttct ggagaagttg catgaagaaa aaaaagcgac
    43201 agcaactgtt actcggatga tctcaagtct cagaagattc catcagtttt tacggcaaga
    43261 gcgtatcact gatcatgatc cgatgcaaca tatcgatacg ccgaagaaag cacagaaatt
    43321 accaagtaca ttgactctga cagaagtaga aaagctgatt gaagcacctg atacgacaaa
    43381 aacgttaggg ataagagatc gtgcaatctt ggaagtcatg tatgctactg ggatgcgcgt
    43441 cagtgaattg attggattga aattgggaga tcttcatctt tctcttggac tggtacagac
    43501 agttggaaaa ggagataaag agcggatcat tcctttaggt gattatgcga tccaatggct
    43561 ggaacgctac ttagacgaag cacgtccatt acttgtaaag gacgcatctg aaatgcatgt
    43621 atttgtcaat aatcatggga aaggtctttc tcggcaagga atctggaaaa atctgaagca
    43681 gttagtacga gaggctggga tttacaaaga agtaacacca catacgctgc ggcatagctt
    43741 tgccacacat ctgctagaaa atggagctga tttgcggaca gtacaggaat tgttaggtca
    43801 cgcggatatc tctacgactc agatttatac acatatcacg aagaaaagaa tgacggatgt
    43861 ttataagcag cattttccaa gggcttagtc ataggaaggt gagaagatgt taacacatta
    43921 ccggaaagaa aaccgtaaaa ttgctatggg actattgagt ttccataaga aactgacagg
    43981 taaaacttct ttgttgaagg agattgatac gtacgaatct gaagacgatt atgaactttt
    44041 tttctttacg ccagaaggtt caaccaacat tcaagggatt attggtattt actgggcaac
    44101 gaacgatcag ctgatcatcc atgacatttc tttgaatccg tcttatcgcg gtgagaatat
    44161 gggctttcaa atgttagatg aattacagga aaagtacccg gatgtctcca tccgtgcaac
    44221 tgaaatcaca gagccttaca ttggaaaatg gctagcaaag aaaaagaaga aagagtgaat
    44281 gagttgacgg agatcaatat taaattagat gtattcgagg gtcctctcga tctgctgctt
    44341 catctgattc agcaaatgga aatcgatata tatgatatac cgatcgctac gatcacggag
    44401 caatatatga attatatcca tacaatgaaa acactcgagc tagctgttgc aggagaatac
    44461 ttagtgatgg ctgctacatt gatggcaatc aaaagcaaga cattgcttcc tgtccaagaa
    44521 ttcgtcacag acgatgaaga attatgggaa gaagatcctc gagaagaatt ggtcactcag
    44581 cttttagaat accgtaaata taaatatgca gctgaaagac tgacagaaaa agcagaggaa
    44641 cgaagtcttt attacacaaa agaacctatg aacatcgatg ggttagcgga tgctgaaaag
    44701 ccgttgaagc gaggacaagt caaaaaaatc gatttgatcc gtgccatgca gaaaatctta
    44761 gaacgtaaga aattttctca aaaagtggaa aaaacgatca cgcccgatga cacaacgatc
    44821 gaagaacgaa tggtatttat cgaagagcgt ataaaaagaa atgcgcatgg ctgtactttc
    44881 gattcttttt ttgagtcacc ttctaaaagt gaagttgtca ctacttttat ggctttgcta
    44941 gaattgatga aaaaagggca gatcattgcg caacaaaaag aaaactatga atcaattatg
    45001 ctttatccag cagtaggaga taccgaacat gacgaaatta agtgaacttg aagcccttct
    45061 ttttattgtt ggcgaggaag ggatcagtaa tgaagaatta agcggactgt taaatctcag
    45121 cgaagcagaa gtcacaagtt tagtgaaaga attaaaagaa tcttacactc aaaactcgca
    45181 ctcagctttg catatttttg aaacggaaag ccattatgta ttaacgacta aaaaagagct
    45241 ggctccctta cttaagcgat atgcgcaagg gacatcaaac acattatctc aagccgccgt
    45301 cgaaacctta gcaatcatcg cttataaaca gccaatcaca agagctgaaa tcgagcagat
    45361 tcgaggagtt caggtttcag gagcggtaca gcgtctagct gcccataaac tgattgaaga
    45421 aaaaggtaga gtagaaggac caggtcggcc gatattatat ggaacaactg gctacttctt
    45481 agattatttt ggtttgaaat cattagaaga actgcctgat acacaagaaa tggaaatttc
    45541 acttgaagaa gacgtgtcac cagatctatt ctttgatgga atgaataaag gagaataatt
    45601 gtaatggaga gattgcagaa agtaattgcc cacgctggca tcacttctcg tcgaaaagca
    45661 gaagaattca tccttgcagg acgtgtaaaa gtaaacggac aagttgtaag ggaattaggg
    45721 ataaaagttg ggaaacatga cactgtggaa gtggatgaag tcccaattta tcaagaagaa
    45781 tacggttact atttattgta caaacctaaa ggagttattt ctgctgttgc agatgacaaa
    45841 ggaagaaaag ttgttacgga tcttttgccg atggtaaaag aacgtatcta tcctgtaggt
    45901 cgactggatt acgatacttc ggggatcttg ctactgacaa atgatggaga ttttgctcag
    45961 cgcctgacac atccaaaaca tgaagtggat aaagtttacg ttgcaaaggt aaaagggatc
    46021 gctacaaaat cgatgcttgc acctttgaca aaaggaataa agatcgaagg acgaaaaaca
    46081 tctccagcta aattccaaat tttatcagtg gatcctaaga caaaccacag tatcgtggaa
    46141 ttgacgatcc acgaaggacg taatcatcaa gtgaaaaata tgcttcaagc agttggtctt
    46201 cctgtgcaaa aactaaaacg tgaaaaatac ggagatctga ctttacaagg cctacgtcct
    46261 ggggattacc gtgaactgaa caaaaaagaa gtcagcagtt tgctgaacca ctcaaaatga
    46321 acacttactt tttataagtg ttagatgttg cgttttttga atagatatgt ataatgaata
    46381 tgtaaacaaa aattatataa ggttcgtctt caggggcagg gtgaaattcc cgaccggtgg
    46441 ttatagtcca cgacctattt tgcaaaaaaa tagctgaatc ggtgaaattc cgataccgac
    46501 agtatagtct ggataaagaa gatagagctt atttgacgac gcttgatcaa ataactctaa
    46561 ctctattttc cctggaaaat agagtttttt catttggaga gaaacgtcaa aaagttcgct
    46621 gaagaggagt cctaacagga ggatttcaaa tgaagaacac ccgtgtacag aaaatggttg
    46681 cagtagcgat gtttgctgcg atcgcattag ttttacagta ttttgctttt ccgatcatgc
    46741 cggcttttag ttttttgaag atcgatttta gtgatatctc ggtattgatc agcatgttct
    46801 tattcggtcc agcggccgga gttgcaacag cgttcttgcg ttcagtatta catctgctga
    46861 ctacaggttt ttctccggat aatttggtag gagacactgc tagtttctta tcaacaacga
    46921 tctttacatt cccgatttat tatttcttta gtgtaaagaa acagcataaa ggaagaaaca
    46981 aatttttagg tgtcattaca ggaaccatcg ctctaactat ttttatgagt atcgcaaatt
    47041 atttcgttat tacgcctctt tacttaatgt ttttagggct gaacgcaaca cagatgctgg
    47101 gcatgtcttt agcaaactat gtactgattg ggatcgttcc tttcaacttg atcaaaggat
    47161 tcatcgtgag tgctgtcttt ttagtgctgc atgcgcaact tcttccatgg ttaagtcgaa
    47221 aacaacatca gttcgaacaa cgtcatacag cagtcaaata aatatcaaaa agatcaagaa
    47281 atttcttggt cttttttttt ggaaaaaaat acaagacatg caataatgta aacgttttat
    47341 ttgtttgttt tgagtatttt tttgatttat gcataaaaat caatcaattc tttgcaaatg
    47401 tgaaattctt ctccttttaa aagacgaaaa tgtttgttta taaaaaaaag gaaacgctac
    47461 aatgaaaaag aagaaagctt taaaaacctg aaaaaagagg agggaatagg gaaaaacgaa
    47521 ctttttgaac aaaagtttta caaaatgcgt gttattattt ttgttctgat actctttttg
    47581 ataaaataac attagagcca aaattgttgt ctctaacgga aaagaaagga agaagaagat
    47641 ggaacaaaca aaaaagaaaa aatttcaaat gccttcagcg tatacggtct tatttattat
    47701 tattgcagta atcgctgtac ttacttggtt tataccagct gggcactata gtgtagacga
    47761 tgcaggcaac atcgtcgctg gatcatatga acgagtacaa caaaatcctc aagggctgtg
    47821 ggatattttc atggcgccaa tcaatgggat gctaggtgta ccagcggggg agctaactaa
    47881 agaaacacct gctgcaatcc caatctcttt cttcattttg gttgttggtg gatttttagg
    47941 tattatcaac aaaacagggg cactagatgc cgggattgct tcagttgtga agaaattcaa
    48001 aggaaaagaa aaaatgctta ttccagtatt gatgctgtta tttgcattag gcggctctac
    48061 ttacggaatg gcagaagaaa cgattccatt ctatgcttta ctgatcccag tcatgatggc
    48121 tgtaggcttt gatacagtag tagctgtagc aatcgtatta gtagggtctc aagtaggctg
    48181 tctagcttca acggtaaatc cttttgcaac aggcgtagct tcacaagctg ttgggatttc
    48241 gatgggtgaa ggtattggtc ttcgattctt gatgttcgtt attttgttag ctatttctat
    48301 tgtatatgtg tatcgttatg catcaaagat cgaaaaagat ccaacaaaat cattagtata
    48361 caaccaacgt aaagaagata tgaagcattt cgatattgaa gcaatcggtc gtcaagaagt
    48421 aatcacgaaa aaacaaaaac atgttaatgt attgttcttt attacttttg gtatcatgat
    48481 catcagtttg attccttgga caaccttgaa tgcgaatttc acgatttttg aatcattgac
    48541 aaactggtta acaaaccttc cggtactagg tacggttcta ggtaaaagca tgcttccatt
    48601 aggtgactgg tacttcccag aaattactat gttattctta gtaatgtcca tcgtagtagc
    48661 aatcacttat ggcatgaaag agtctgaatt tgtctctgaa tttttagctg gtgcttctga
    48721 tttgatcggt gtagcaatcg tagtagctgt tgctcgtggt atccaagtgg ttatgaacaa
    48781 tggattaatc acagacacca tcttacattg gggcgaacaa ggattaagtt cattatcttc
    48841 aagtgtattc atcattatta catttatttt ctatatccct atgtcattct tgattccttc
    48901 aacttccggc ttagctgctg caacaatggg aatcatggga cctatgggtg aatttgccgg
    48961 cgtcggtaag gatttagtaa tcactgctta tcaatctgca tctggtttag taaacttaat
    49021 tacaccaaca tctgctatcg taatgggtgc tgtagcaatt gctcgtttcg atgtttcagt
    49081 gtggtggaaa tttaccggta aattaattgc gatattattt gtagccatct gtgtgatcct
    49141 aggtgtagca gcaatgttct aaacctagac aaatacaggt acaaggtcta tcataagaat
    49201 gaagaaaccg ataaacggct atcgataagc acgtggataa gtcaatagct ccattcagtg
    49261 agtgtttttt ctttcatcat ttgttaagaa cattctgctt gctgatggag caggcttaaa
    49321 acgtcattat ttgagaagaa gaggttgtgt cggaggaatt tgacatgacc ctttttaaca
    49381 tattaggagg ataatatcat gaaaaaattt gtgacagaac aacatcatga acaagcatta
    49441 gaatcattga gcgaattgat ccgaattcct tccgtactag atgaagcaga ttcaggacaa
    49501 ggacatccct tcggtaaaaa agtgattgaa gctttggata aagtattgga aatcagtgaa
    49561 aagctaggat ttagaacatt taaagatcca gaaggctatt acggttattc agagattggc
    49621 tctggagatg aattattcgg tatcttgtgt catatggacg ttgttccagc aggggacgaa
    49681 aataattggg aaacaaaacc attcgatcca actataaaag acggctggtt agttggtcgc
    49741 ggatcccaag atgacaaagg tccttctatt gcggcaatgt atgccgtcaa agctttgatt
    49801 gatgctggcg tggaattcaa gacacgtatt cgttttatct ttggtacaga tgaagaaaat
    49861 ttatggcgtt gtttagaaaa atataacgaa aaagaagaag gaattacgca aggatttgcg
    49921 ccagatgctg aatttccttt aatttatgca gaaaaaggct tattgcaagc ttacttgaca
    49981 ggaccaggaa cgaacgagtt ttctgtaaaa gctggaggag cgttgaatgt tgttcctgat
    50041 gcagctcctt actctggaga aaagctttct gaagtaaaag aagcattgaa aaaacacgaa
    50101 ttcgatttcg aagaacaagg tgaaggcatc gtcgttcttg gtaaaagtat ccacgcgaaa
    50161 gatgcagcac aaggagtgaa tgctatttct cgtctggcaa ttgctctttc agaagtattt
    50221 gattttggcc caatcaattt cttaggaaaa ttagttcaag aaaatgcaac tggtgaagct
    50281 gtcgtgggca aaacagaaga tgaacaatcc ggcgagctaa cgatgaactt tgcaagtttg
    50341 gaaatcacac cagaacaaac aaaaatcggt gtagatatga gaatccctgt tacattcaag
    50401 aaagatgatt tagtagctaa attaactaaa acagcagaaa aatatgggtt gacttatgaa
    50461 gaatttgact tccttgattc attatacgtg ccactagaca gtgagttagt gaaaaatcta
    50521 ttggggacat atcgcgatat tactggagac atgactgaac cgtttgtatc aggcggcgct
    50581 acttttgctc gtacgatgaa ccagtgtgtg gcattcggtg cgatgttccc tgatactcct
    50641 gactttatgc accaggcgaa tgaacgatgg gaattaagta gtatgtataa agcaatggaa
    50701 atttatgcag aagctgtgta tcgtttatgt gctaaataaa aataaacata caaaaagggc
    50761 ggatattcaa atggatattc cgtctttttt tatttgatgc tggaaagttt gcatttctct
    50821 cttatttttt taaggtataa tcatacttga ttaagaaaaa ggggtcactc agatagaaaa
    50881 ggtgggagaa agtgaaaata tttagacgaa tactaattgg cttagtcatc attttaggat
    50941 tactcggtgg agccggttat tactatatac agcaaaatac gtacgaacca tcgtcagaag
    51001 cgcaagtgtt ggtaaaagaa ggaaaaaaca aagaagatta cttatttttt gaaggagaga
    51061 aaaagaatca tggaaagtct ccattactta ttttttatcc tggtgctctc gtagagccag
    51121 aaagttatag tatttgggcg caagatttag caaaaaacgg cttttcagtc gctattgtca
    51181 aaatgccact tgatctagca gtgatgggcg gaaacaaagc ggataaggtc aaagaagatt
    51241 ttccaaattc cgattatgtg atcggtggcc attcattagg tggcgtaatg gcaagtcgtt
    51301 atgtcaataa gaatcattca gacaaacatt taaaaggggt attcttcatg gcaagttatc
    51361 ccgacaaaaa aggaacattg acagaatcag ctgttcctgt tttatcgatc acggcgacaa
    51421 aagataaagt attgaatcag gaagcttatc aagaagctaa gcagtattta ccggaaagaa
    51481 cagagtatgt atcaatcaat ggcggaaatc atggaggttt tggcagctat ggtgagcaaa
    51541 aaggagatgg agaggcagaa atttctaacg cagaccagca aactgtgatc gtcaatacat
    51601 tggaaaactg gctgaaaaag ttgaaataat ataaatgggt cctatagggt ccgtgaaaaa
    51661 actagtcaat taactataga tagcaaatga atctttcaaa ataagtcggg atttcacgga
    51721 acaagagaaa cagatcccgg cttattttca agtttagaga acttagtgta cgtttttaaa
    51781 gtttcgttta tatttatatt ttattttcta ataaaatcgc tcgaactgga catttttgat
    51841 acgctttttt tacatatgtt tcttcttccg gcatcacgaa ctgttgatga gcctctggtt
    51901 cttgggcaaa taaaacgatt ccttcttcat cataatcgaa aatatctggc gcttcgattt
    51961 gacaaagacc gcatgcaata cagcgttcag gtacaagttt acatagtagt gacatttcta
    52021 accatcctaa cttaaggaga ataatatgat tgtttttatt ttatcgctat tttcatcagg
    52081 acacaagctg cggattagtt ctctttacca actccttgtg ggaaaacgaa cgacttcagt
    52141 acttatttat ggatttaccc acgaactttt gtttatccat aacagttttc cagaattgaa
    52201 gcaggataag ttttatcaaa ttttgcaaaa aattgcgcag caaggttgga tcgaaataaa
    52261 tgaaaatgaa gcaaagctaa cgcctgcagg ggctgatatg ttgtccgaac atcaaataga
    52321 acatactggt ttgcgttttg accgctatgg cagaacaggg gaaactagtt ggcggctcat
    52381 taaatttgct gttcaagtaa tttctaatct ggcaacgggt attcaagact atcttccagc
    52441 agagacaagt cctttttata ctttccaact aaaaaaatgg cttagtgaaa gccaattgcc
    52501 acgtgaaatt ttgattgata ctgcgtatga gagtttggtg cagctgtttt cggagatacc
    52561 agaagaagca gcagattttt tagctaacca attatctgga aatgagcgaa cagggctgct
    52621 tccttatcag ctggcaaaaa acaatgatga gtcagcggtt tatctgcaac aaagcagatg
    52681 tatccacctt ttgttagcac aaatcgaaaa acggccagat tcgctttggc acgctttgat
    52741 cgattcatta ttacagcaaa atttcaatca aagcatgatg atcaccaagc agatgtttat
    52801 gaatggtcag acaattgacc agatcatggc aatccgtcat ttaaaaagag gaacagtaac
    52861 agatcatctt attgagtggg ccttgttttt tgatgatttt ccatacgagt ggattctctc
    52921 tgcagaaaca atcgaacgtt tggaaccaaa taaggattcc gtgcgagagt ggcgctttag
    52981 cgaatggaat gtagatggac aattagatta tggagaattt cgtttgtatc aaatctatct
    53041 attgagaaag gaagcgatac agaatgttaa taaatgaatt aaaaaaatat tttggatttg
    53101 attcatttcg tcccggccaa gaagaaatta ttcaggcgtt gcttgatgga gaagatactc
    53161 tcgctatttt gcctacagga acgggaaaaa gcctttgcta tcaattgacg gggtatttaa
    53221 tggaaggtct ggtcatcatc gtgtcaccgc tgctttctct aatggaagat caagtgacgc
    53281 aattacaaaa acgaggggag aaacgagtag ctgctttcaa tagtttactt tcgcaatctg
    53341 aaagaagata cgtcctccgt catctatcgc aatataaatt tttgtttttg agtcccgaaa
    53401 tgttgactaa tccttctctt ttagagcatc tgaaaaaaca aaatattgcg ttatatgtag
    53461 tagatgaggc tcattgcgtg tctcaatggg gagttgattt ccgtccagaa tatcaacagt
    53521 taggaaaaat ccgaaagctt ttaggaaacc cggtcacact ggcactaacg gcgacagcaa
    53581 cagatttagt agcaagagat atacgtcatg tactatttga tcgaccacca aaagagatca
    53641 gacaatcagt caatcggcaa aatatctcgc tttttgttcg gaaaacgcag caaaaagaac
    53701 aagaacttga acacttcatg gaaagagcac aaggagcggc aatcatttat tgtgcaacaa
    53761 aaaaagaagt cgaacgattg tatcatttat tcagggaacg ttttacagtt ggatactatc
    53821 acggtggtct tgatgcagct caaagaagac aacttcaaca gcagtttgta aaaaatcagc
    53881 tgcagtttct cattgctacg aatgcatttg gtatggggat cgataaatct gatatccgtt
    53941 atgtggtcca ttatgatttg ccagacagtc tagaaaacta tgtacaagaa atcggtcgag
    54001 caggcagaga tcaggaagaa agtgcagcaa ttctttttta tcaaagtggg gatgaacgta
    54061 tccattattt ctttaatcaa ctttctagag aacagcgaca aagttttgag ctttatttgg
    54121 aatatgccac agagcaagct ccctttgatg agctgcaaaa aaaatggatg gagctgatcc
    54181 agcagtctga aaaaccagaa aattgggtgg aacggctcaa acgtcaggaa aaagaaaaag
    54241 aattccgcct gcagcagatg cttcgctata ttaatgaaga aaactgccgc agaaaattca
    54301 tcttagctta ttttggcgaa aaactctccg aaaagccgca gaattgttgt gatattgatg
    54361 gagcaaaagc agaacttctg ccaaagagga agcttttttc taagactgaa caacttcatt
    54421 gggaaacgat tttactaaat ttatttaaaa aaaacatgga acattgattt tttaggacaa
    54481 gacacttttt cctatggtat aatacacacg atagagttta ggaggtaaaa cagtgagcag
    54541 aaaagataga catcaatcta cagaaaataa cgaaacacaa gaaccatggg aacaaccaat
    54601 ctacgataca gatgatgaag tttcatcaag aagttctcag agacaacaaa agaaaggaaa
    54661 tacattattt ctttcgctat ttttgatttt actggtctta tgtatcgcta ttccagcagg
    54721 tgcttatttc tggatcagaa atggatcaag caacaatgca acagcagcaa cttcttctga
    54781 aacttcgaca tcagtagtag aaagttctac aagtacaaca aaagaggagt caactgagac
    54841 ttcaacagta gaatctagta caatcgcgga agaatctact gtgtctcaag atacaggtgt
    54901 aacgtcagaa agcagtattg cagcagagac aacaccgact tcctcaagtg aggcaactta
    54961 tcaagcaggg gattcaagca gcaatgcagc agaaacaaca ccttcttcat cagctgcagc
    55021 cggttcaaca acgactgttc aagcaggcga aggtccaaaa caagtggctg agcgtgcagg
    55081 gatcaccact gatcaattgt ttgaattgaa tggcttagat ccaaacaact ttatgcttta
    55141 ccctggtcaa gaattaagaa ttaaataata atagccgcgc tttgcggctt tttttctgag
    55201 aaaaaggagt tatagcatga cacaaatcag tattgcaatc gacgggcctg cttcatctgg
    55261 gaaaagtacc gttgccaaga tattagcaaa agaattgaat tatatttata cagataccgg
    55321 tgccatgtat cgcgcagtaa cttatttagc tattacgaac aatgtatctt tttcagatga
    55381 agaagggcta gtttcgctga tcaaaaagta tcctatctct ttttcgcaac aagaagatgg
    55441 acagcatgta ttcatagcat caaaagatgt gactttagaa atccgtcaac cagatgtcac
    55501 aaaagctgtt tctgaagtct ctgcacatgg aaaagtcaga gaagaattag ttgctgtcca
    55561 acgaaaaata ggggaacgcg gtggcgttgt catggacgga agagacatcg ggacagctgt
    55621 attaccgaat gcagaagtga aaatcttttt agtagcaagc gtaagtgagc gtgcagaaag
    55681 acgtttcaaa gagaaccaag aaaaaggaat tccgactgat cttgaaacac tgacgaaaga
    55741 gatacaggaa agagaccatt atgattcaac aagggacgtc tctccgctga agcaagcaga
    55801 ggatgctgtt cgtatcgata cgactggcaa atcgattcca gaagtcgttg cagcaataaa
    55861 agctgttgtt ttgaaaaaag gttatcttct tttttaaatt aagaaaaaaa atgaaaaaca
    55921 attgtttttt caaggaaaac gaacgaaatc gctttatttt ttttgaataa tcaattaaac
    55981 taaaaacagt accgtactta cggcagaatg ttggttagga ggacaagtgt tatgacagaa
    56041 tttgatcaaa atcaagagaa caaccagtca atggaagacg caatgaaaag cgtacaagaa
    56101 gtaaaagttg gcgatgttgt taagggcgaa gttttagtca ttgaagacaa acaagtgatt
    56161 gtcggaatcg aaggggctgg agttgaagga gtcgttccgg caaaagaatt atcaactttg
    56221 ccggtagaag atatcagcga agtagtaaaa gtcggtgatg tattagattt agtcgttatc
    56281 agtacgatcg gcaaagataa agaaaacggc agctatctac tttcaaaacg ccgtttagat
    56341 gctaaaaaag tttgggaaga tatcgaaaga gatttccaag agggcaaggt catcgaagca
    56401 cctgttacaa atgttgtcaa aggcggttta gtcgttgacg tcggtgtacg tggttttgtc
    56461 cctgcatcaa tggtggaaga tcattttgtt gcagactttt cagactataa aggcaaaaca
    56521 ttgagcttta aaatcatcga aatcgaacca tcagaaaatc gtttgatctt atcgcataaa
    56581 gcggtagtgg aaaacgaaag agaagaaaag aaaaaagaaa ttctttcaac tatccatgag
    56641 ggagatgttc tcagtggacg tgttgcacgt cttactgatt ttggcgcatt tgtcgaccta
    56701 ggcggaattg acggtctagt ccatgtctca gagatttcac atagtcatgt agcaaaacca
    56761 agtgatgtat tggctgtcaa tgatgatgta aatgtcaaag tgttgtctat caatcctgaa
    56821 caagaacgtg tttccttgtc aatcaaagac acacagcctg gaccttggtc agaaatcgat
    56881 acaaaagctc cagttggcac agtattagac ggaacagtta aacgtttgac aagcttcggt
    56941 gcctttgttg aagtgttccc tggagtagaa gggctagtcc atatctctca aatttcacat
    57001 aaacatattg cgacaccaca tgaagtgctt catgaaggtg acgaagtgaa agtgaaagta
    57061 ttagagatcc atccagaaga acatcgtatt gcattgagta tcaaagcttt agaagaaaaa
    57121 ccagcttcag aagaagaacc aaaaaatgtt gagtcttatg aattaccaga agaaaatact
    57181 ggatttacta tgggagacat tttaggtgat gcgttgaaag aagaagtaga agaaaaagca
    57241 accgatgatt ctgaaaaata attgattttg tatctgtgac tgagatgaaa gcagctgctt
    57301 ttgtctcagt ttttcttttg aaaagcgatt agtatttcaa taaggaataa aaatacttcg
    57361 tttaattgac aatctatgct tgaaagttgg caatgcattc gttaaactaa gtgagattgg
    57421 aaacttgtga ggaggaaata atatggcaaa tccaacaatt gcaatcgttg gccgcccgaa
    57481 cgtcggtaag tctacgattt ttaaccgcat cgctggtgag cgtatctcga ttgtcgaaga
    57541 tactcctgga gtaactcgtg atcgtattta tgcaaaaggt gaatggttag gtcgagaatt
    57601 cagcgtgatc gacacaggcg gaattgatct tggcgatgaa ccttttatgg atcagatcaa
    57661 gcatcaagca gaaatcgcga ttgaagaagc agatgtaatc atttgtgtag tcagcggacg
    57721 cgaaggcgtg acagacgcag atgagatggt tgcgaaaatt ttatacagaa gtaataaacc
    57781 agtgatttta gcagtcaata aagtagataa tccagaaatg agaaacgata tctatgaatt
    57841 ttattcctta gggctaggcg atccttatcc tgtttcagga agccatggac tagggattgg
    57901 tgatatttta gatgaagcag tgaagtattt ctctgaagag actgaagaag aggacgacga
    57961 cacgattaag tttagtttga ttggtcgccc aaatgttggt aaatcctctt tgatcaatgc
    58021 gattttagga gaagaacgtg taattgtttc ggatattgaa ggaacgaccc gagacgcaat
    58081 cgacacccac ttcgtttctg aaagtggtca gaaattctta atgatagata cagctggtat
    58141 gcgtaaacgc ggaaaagtat acgaaaatac tgaaaaatac agcgtgatgc gtgcaatgcg
    58201 tgccattgac cgttctgata tcgttttgat ggtactgaat gctgaagaag ggattcggga
    58261 acaagacaag cgagtagcgg gttacgccca tgaagctggt cgtggaatta ttatcgtcgt
    58321 gaataaatgg gatcttgtaa agaaagaaac caatacaatg cgtgatttcg aacaagagat
    58381 tcgtgatgaa ttccggtatc ttgattacgc tccaatcgtt tttgtttctg cagtgactaa
    58441 acaacggttg gaacgtctgc ctgaaatgat cgaacaagta agtatgaacc agaatcttcg
    58501 tatctcttcg gctgtgttga atgatatcat tatggatgct gtagcaatca atccaacacc
    58561 aacagataaa ggaaaacgcc tgaagatttt ttatgctaca caagtcgctg tcaaaccacc
    58621 tacatttgtc gtttttgtca atgaagagga attgatgcat ttttcttatg aacgtttctt
    58681 agaaaatcaa atcagaaaag catttacttt tgaagggacg tccatccgaa ttatccctcg
    58741 taggagaaaa taggcatttt accatatcga cgtttttttt tcaaaagaaa aagacagttt
    58801 cgtttgttac gtttctatga ctaaaaaaag catgtgaaaa ttggtaaaaa ccttgctatt
    58861 aagcggttca tatgatatcg tgataacaga atattgaagt taatcaatat ttctttttaa
    58921 acttctggac cactcagaaa gttttaacta aatgatattt ctatcatatc tcttgtggag
    58981 gaggtgaatc tatccatggc aaacaaagca gaattaatcg aaaaagttgc ttcagctact
    59041 gatttaacta aaaaagatgc aactgcagca gtagatgctg tattttcaac tattcaagat
    59101 gctttagcta acggcgaaaa agttcaatta atcggttttg gtaactttga agttcgcgaa
    59161 cgcgcagctc gcaaaggtcg taacccacaa actggtgaag aaatcgaaat tccagctagc
    59221 aaagtacctg cattcaaacc aggtaaagca ttaaaagacg ctgttaaata agacagttga
    59281 aaaagcgctt gtggctctag ggctacaagt gcttttcttt ttatttccta gcagaaaagg
    59341 aataaataag agacagagat tccgaatccg tatgtcatac atagaaaaca catgtatttt
    59401 atttaatttt tatttatttg caagttatga ggtgagcttt gctcttatct tttctagaat
    59461 ttgcttacta atggtaaaat aaaaataaga agaggaggga tgcgtatgga acttgattat
    59521 caagtagaag atgcgttgac gaaagtgttt tacggagaaa cgctagtcag tcagctaaga
    59581 gaactttcca ttgatcagcc aatcttattt ttaacgaatc agcgctatta tgatttgttt
    59641 gcagataaga tcaacccgtt atttgcaaat caagcaaaca atgactggta tatttgtgcc
    59701 aacactcaat gcaatcattt aacagaatta aagaacctgc ttgatttcgt caaacgctat
    59761 cccgaaaatc aatccatgtt tatcatcgga tttggaaatg aagggatcat ggatctggca
    59821 ggtttttttc aaaaacatac aacccttgat tcatcactat ggatgatccc tgtatcgatc
    59881 cgttctctaa gccgagcatt aacaccgcag cggacgattt tgcagctacc aaatcgtgta
    59941 gtgctgcaaa ccatcaatct gccagaacgc atcgtttatg atcaaacaat cagcgagcgg
    60001 caggtggacg gaaagcagat tgactttttg acttttatct gttgcggaat gatttgtgat
    60061 catcgttttt tgcaaaatct gtataaaaac tatccaaata aaaagcaatt aacgactcgg
    60121 ccgtttgccg ggatgatcga agaaatgatc tatttttatc aattagaggc agaaaacctg
    60181 tcaaattatg gtaaactgtt tgaacaagct ttttatctga ccgaaaatgg ccatctactt
    60241 tctgctagta tgaaaaaatt tttaggaatg atgtttcatt tcgtgtggaa tctccaagca
    60301 tatccttttg atttccaact aaaaaacttt tttgtgtggc tggacttgct tggctatcca
    60361 atccactggc tggaacagat ttcaaagatg gagtatttgg aaaaagttct ttttttggca
    60421 gaaaaaagca aaaaaatact tgttttagaa aaaataggta taatagacgg ataccaacat
    60481 ccaaacgaaa aagaattatt gagaacaatg acggtatttc aacaaatcgt cagtgagata
    60541 agagggaatt gaaatgaata caaatagcga aaaaatgttg caagctttat cagatgaaga
    60601 cttgtcacaa gcacaaatct ttttagaaaa agcattaaaa gaagacccag cagatatatt
    60661 agctgaacta ggcgaagaat tgctggctat tggctttttg atcgaagcaa aacagatttt
    60721 tgaacaactg atcaaccaat acccagaaaa tgacggactg aacatcccgt tagcagaaat
    60781 tgcaatcgaa gataatgaga tcgacttagc ttttgaatac ctggaaaaag tggataagca
    60841 aagtgattac tatccgcaaa gcttattggc gatagctgat ttgtaccaag ttatcggaat
    60901 ccctgaagtg agtgaagcaa aattgaaaga agcagctggg ttgcttcctg atgaaccatt
    60961 gatccagttt gcgctagctg aattgtattt ttcagttgat cgtttcaaag aggcagcagt
    61021 ggtttatgaa acattgttgg caagcgggat aaatgaaatt tcaggaatct cgatgcagga
    61081 acgtttagga caatccttaa gtatgcaagg agaattcgaa gcagctatcg tacctttaga
    61141 agaagcactg aaagaagaaa ggacagatga tcgactgttc cagctagctt ttacgaatct
    61201 tcaattgaaa gaaaatcagc aggcaatcaa ctatctggaa gaacttcgag aagttaatcc
    61261 gcattatcaa tcgttatatc tatatctagg acaagctctt caagaagaag aaatgattga
    61321 agaagcacaa acagtgttag aagaaggaat caaagaaaat ccttaccaag tcgaacttta
    61381 tcacctggcc tcggaaaatg ctttccgtct gcatgataga cagcgagcag aagaactttt
    61441 actgaaagct ttagaagtag gagacaaaca agatgaaaca ttacttactt taagtaatct
    61501 ttacttggat gatgaaagat atgaagatgt gatacaagtg atcaatcaga tggaagaaac
    61561 tgctaatcct tatgcagaat ggaacctagc ccatgcttat aatgaattag aagactttac
    61621 cgttgcagct gtacactatg aacaggctta tcatgaacta tcacatgaac cagatttctt
    61681 gaaagagtat gcctttttct taagagaaga agggcagctg aaaagagcgc aagaattatt
    61741 gacttattat ttaacacttg aaccaggaga tatggaggca ctgtcattat tagatgacct
    61801 aacagagagg tgagaaaaat gctaattgat gtacgggaaa agaagaattt tttaacgtgg
    61861 atggtcaatc atgtatcttt tagccgaaga gaagtttttt ggatcttgaa ttatcttgcc
    61921 aatcatgaag cgattttaag caatgtccac tttgttgaag gggcgaattt tgcggatcga
    61981 ggactgcaga tcagtgatct atctgttgaa ggggaaccca tgaaattgtt tttgcaggga
    62041 aaagaattta cggacacaga ccagattttt catgaaatcc gtttgaattg gaaaaagcct
    62101 ttatatgtgg aatgtatatt cgaaaatgct tggcagacaa gagaatatct atctatctta
    62161 gaagacaatc cattttcttc ttgggattct tcagtcagtg aagaagatac tgaattaatt
    62221 gaacgatatt ttcaagaaaa agaagaagag gcaaaactaa aaatgcttta tgctcaaatc
    62281 gatcaagcac tagaagatgg agatagggat gcttttttga aattatctga tgaagttaac
    62341 cgaaagatcc ttttgcagac acaaaagaaa agtaaccggg taagtgaaca taacaattag
    62401 ttaaaaatag tatagtacta aaaaagacaa aggtcagctg gatgtggaat ctttcctcat
    62461 agcctatctt tgtctttttt cttatagttt tttcagtaat cttgtctgtg gcttcaaata
    62521 agtaaagcct tgcccttcca cttcatgcac attgatgatt gaaaggaaag ctttttcgtc
    62581 aatctcgtgg acgatcctct tagcttcagt taattcacta gagctaacga ccatatagat
    62641 gatttttttt gaattaccag agaatgcgcc ttctccagaa aggaaagtca cacctctttg
    62701 cagaccggtc atcagtagtg gtgcaatctc ttcgcttttg ttggagacga caagtagacc
    62761 ttttgcagaa tatccgccat ctaagatcga atcaatcaca cgactgaaaa catacgaaac
    62821 aatcaacgta tacatcatac gtttcaagtc gatataggtt aatgaagcaa gtaagacgat
    62881 gatatcaaat gccaataggg aacgccccat agtgatgccg taattttgtt ctaaaatccg
    62941 agcgataata tcactgccgc ctgttgttcc acccatgcgg tagacgatcc cgcttcctac
    63001 acctgcaact aaacccgcaa gtagagaaac gatcagtaga tcatgctgta aattgatttc
    63061 tagtggaacc ctttgccaga tccataaaaa gaatgacaaa gaaagtgtac ctagaacagt
    63121 ataggccaag gaacgtttac cgaggatctt tcctcctagt aaaatcaatg ggatgttgat
    63181 taataaagtc gtataagctg gatcaatacc aaataaagct cttaagatca aggtgatccc
    63241 tgagactccc ccttctgcta aatgattagc gatgttcaag taaacaagac caaatgcata
    63301 aatacttgtt cctataatga taaaaagaac ttcttttact gtttttcgtt tgaccatatg
    63361 aattccagct ttcaattatg tattttcaca gaatttccat ttagaaattc cttcctaaat
    63421 gtagcatgga aattcgattt tctcaattgc tcttatctag gatttgcgtt aaagttttgg
    63481 taagatagtt ttggagggaa aaagatggat aaaaagcgtt ctttatacag tatgcagcag
    63541 gaagtggatg aatatatcca gcaattcaag gtggggtatt tctctccatt agctcagatg
    63601 gctcgattaa ctgaagaagt aggtgaattg gcaagagaag tcaaccacac ttatggagaa
    63661 aaaagcaaaa aggcttctga accagttaac tcggtagcag aagaacttgg tgatgtttta
    63721 ttcgttacga tgatcatggc taattcattg aatatcgact taactgaagt ttttgaaaaa
    63781 aacatggaaa aattcaatca aagagaccat aatcgctttg agcgtaagga cgagtaaaca
    63841 agatgaagtg gtcctggcct tgaagactct gaaacggact tgtcaaacag tcaccatgca
    63901 actgagtctt tatctcagga caagaaacac gcaggaaagg ttggaaaaat gaaattaaaa
    63961 caattacctc tggaatacca aaaggcaatt ccagttctga aaaaattaga gaatgcagga
    64021 tatgaagctt attttgtagg tggaagtgtt cgtgatatct tgctgaacca gccaatccat
    64081 gatgtggata tcgcaacaag cgcatttcca gaagaaatca aacagctttt tccaaaaacg
    64141 atagatattg ggatcgaaca tggaactgtg ttggtattag aaaatgatga acaatatgag
    64201 atcaccacat ttcggacgga atcaacttat caggactacc gtagaccaga tcatgtcgaa
    64261 ttcgttcgtt cgttggcaga agatttgaaa agaagagatt ttacgatcaa tgcgtttgct
    64321 ttgaaagaag atggagaaat catcgatttg ttcgatggtc tgcaagatct agaagaacag
    64381 atcttgcgag ctgtaggcaa tcctcatgag cggttccatg aagatgcctt acgaatgatg
    64441 cgcgggttgc gttttgtcag tcaactaggg ttcaaattag aggaagaaac cttctacgcc
    64501 atcaaagaaa accacgagct attaggtaaa atatctgtag aacgtataaa tgtggaattc
    64561 atcaagatgc tcttgggaaa tgaacgggcc gcgggaatcc atgcatttat tgaaacagag
    64621 tgctacattt gctgtcccgg tttgaaagaa gaaggcgaag cacttttacg ttttgctgaa
    64681 ttaccatccg tcccattgaa agaagagagc caagcatggg cattattgat cagccaactg
    64741 gatctaaaag aaaatgagat tcgttccttt ttgaaatcgt ggaagtgttc taaccaaatg
    64801 attaaagacg ttcaagcact tgtccaagga ctacgacaac gagaaactgg agctttggaa
    64861 ccattcgaat tgtacttctt aggcaaaaaa catgcactgc aagtagaaga attgatgatc
    64921 tattttgacg aaacacctca gatggatgcc gtaggagaat cctatgatcg tttacctatc
    64981 aagtcattaa gcgaattagc agtagatggt aaaatcttgc tagaagaaac tggaaaaaaa
    65041 cctggtaagt gggttagtga agctttgcaa ttagctgaaa aagccgtcgt agaacaaaga
    65101 ataaaaaatg ataaaaaaca ggttttggat tttttatcga aagaaaaatt gatttaaaaa
    65161 acactagact gtatctgctc agctttgttg gctacttaaa gtgggcagat acgtcattag
    65221 aagaaaaaac ataagatgtg accacttaca taaatttgtg ctaaactgag gtagtacaag
    65281 aataaattac atcataaagg agtcttttta atgagtaaag aaatgacagc gctaaaattt
    65341 tattttagaa atggagaaac ctggacgatc aaccgccgtc atatcggcga tctttggatc
    65401 aaacaaatca caacaagttt tggacgaatc aatggcagtg aatttgttga aatccatccg
    65461 tgtgctggat ttaaaatcga aatcttccat gaaggggacg cagttgcgac acatgatatc
    65521 aacctaggcg gactggaaat gggcatgttt aatcgcgcat tgaaatacga agatatcgag
    65581 cgaatggaaa tcctttaccg aaatggcaca cctgatcttg tgtacttccc atatctagat
    65641 aaaggaacag aaggattaga caatcaatat caatcaacaa aaatcagcga aaaaacaggt
    65701 aacttgtata tcgtgatcaa tccagatcaa cgtgtagaag atgtatacgg ggaatttttc
    65761 gaataaatcg atttttacgc aaaaatgagg ctgtgaaaga gatgtgtctt attactactg
    65821 ataggctgtc tcttccacac cgtttattca gaataaggga ctgtgacaag atttttgtcg
    65881 cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga aagtaaacat
    65941 ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata ctatttggaa
    66001 tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg atgaaacaat
    66061 gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg tataggagat
    66121 ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc gctatggcgc
    66181 cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa atatattgat
    66241 gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa aacgtgtaca
    66301 gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa ttttaaagaa
    66361 aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat ggacgatgga
    66421 atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca tagctagccg
    66481 cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg tattaggtct
    66541 gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta tgattattgc
    66601 accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca aaaatttcgg
    66661 gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg taggtgcgac
    66721 gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg gagcagcgtt
    66781 aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata tccctaaaaa
    66841 ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg ttactgcctt
    66901 ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg cggggatgag
    66961 tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct ggttcaaaca
    67021 aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt atctgctgat
    67081 cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg tatctggaat
    67141 cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa tctctgtgtt
    67201 tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt ttacactgaa
    67261 tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc cagtatgggg
    67321 agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct ctgtcatgct
    67381 ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg gcagtaaaaa
    67441 gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa agggaacagt
    67501 cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt tttaccagcg
    67561 gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca tagggatcat
    67621 tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga atgctttgat
    67681 gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg atcgtaatac
    67741 aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga tacgtgatct
    67801 gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac aagcactgat
    67861 tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc tttcttctaa
    67921 tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca caagccagat
    67981 tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa tcgttctcca
    68041 tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta gtgatgaaga
    68101 tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg aaagtttaga
    68161 taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc aacgcaaact
    68221 tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc agcaagatag
    68281 tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca ttgatgaata
    68341 cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga atatcaattt
    68401 gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat ttgcgtttcg
    68461 agcaaagtca aaaaaaacga gtccaataaa ataa
//
LOCUS       DAIGUC010000007        67363 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.007, whole genome shotgun sequence.
ACCESSION   DAIGUC010000007 DAIGUC010000000
VERSION     DAIGUC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.007"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(7..1269)
                     /locus_tag="NOB46_000451"
     CDS             complement(7..1269)
                     /locus_tag="NOB46_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057427.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            complement(1262..2161)
                     /locus_tag="NOB46_000452"
     CDS             complement(1262..2161)
                     /locus_tag="NOB46_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057428.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            complement(2306..4084)
                     /gene="uvrC"
                     /locus_tag="NOB46_000453"
     CDS             complement(2306..4084)
                     /gene="uvrC"
                     /locus_tag="NOB46_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCI1057429.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            complement(4266..4580)
                     /gene="trxA"
                     /locus_tag="NOB46_000454"
     CDS             complement(4266..4580)
                     /gene="trxA"
                     /locus_tag="NOB46_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCI1057430.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(4667..7027)
                     /locus_tag="NOB46_000455"
     CDS             complement(4667..7027)
                     /locus_tag="NOB46_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCI1057431.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(7159..7689)
                     /locus_tag="NOB46_000456"
     CDS             complement(7159..7689)
                     /locus_tag="NOB46_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HCI1057432.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELW"
     gene            complement(7747..8184)
                     /gene="zapA"
                     /locus_tag="NOB46_000457"
     CDS             complement(7747..8184)
                     /gene="zapA"
                     /locus_tag="NOB46_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCI1057433.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            8386..9303
                     /locus_tag="NOB46_000458"
     CDS             8386..9303
                     /locus_tag="NOB46_000458"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HCI1057434.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(9559..10470)
                     /locus_tag="NOB46_000459"
     CDS             complement(9559..10470)
                     /locus_tag="NOB46_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI1057435.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(10873..11451)
                     /locus_tag="NOB46_000460"
     CDS             complement(10873..11451)
                     /locus_tag="NOB46_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1057436.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(11471..12139)
                     /locus_tag="NOB46_000461"
     CDS             complement(11471..12139)
                     /locus_tag="NOB46_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057437.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(12154..13224)
                     /locus_tag="NOB46_000462"
     CDS             complement(12154..13224)
                     /locus_tag="NOB46_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057438.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(13395..14759)
                     /locus_tag="NOB46_000463"
     CDS             complement(13395..14759)
                     /locus_tag="NOB46_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1057439.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLFEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(14756..16315)
                     /locus_tag="NOB46_000464"
     CDS             complement(14756..16315)
                     /locus_tag="NOB46_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057440.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(16371..18851)
                     /locus_tag="NOB46_000465"
                     /pseudo
     CDS             complement(16371..18851)
                     /locus_tag="NOB46_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18835..19170)
                     /locus_tag="NOB46_000466"
     CDS             complement(18835..19170)
                     /locus_tag="NOB46_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057441.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(19184..20218)
                     /locus_tag="NOB46_000467"
     CDS             complement(19184..20218)
                     /locus_tag="NOB46_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI1057442.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(20308..20988)
                     /locus_tag="NOB46_000468"
     CDS             complement(20308..20988)
                     /locus_tag="NOB46_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI1057443.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(21272..22375)
                     /locus_tag="NOB46_000469"
     CDS             complement(21272..22375)
                     /locus_tag="NOB46_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI1057444.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(23004..23474)
                     /locus_tag="NOB46_000470"
     CDS             complement(23004..23474)
                     /locus_tag="NOB46_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HCI1057445.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            23804..25444
                     /locus_tag="NOB46_000471"
     CDS             23804..25444
                     /locus_tag="NOB46_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCI1057446.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            25598..26920
                     /locus_tag="NOB46_000472"
     CDS             25598..26920
                     /locus_tag="NOB46_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HCI1057447.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(26988..27422)
                     /locus_tag="NOB46_000473"
     CDS             complement(26988..27422)
                     /locus_tag="NOB46_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1057448.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(27487..28323)
                     /locus_tag="NOB46_000474"
     CDS             complement(27487..28323)
                     /locus_tag="NOB46_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCI1057449.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(29065..29691)
                     /locus_tag="NOB46_000475"
     CDS             complement(29065..29691)
                     /locus_tag="NOB46_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057450.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVHFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(29986..30321)
                     /locus_tag="NOB46_000476"
     CDS             complement(29986..30321)
                     /locus_tag="NOB46_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI1057451.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(30308..30592)
                     /locus_tag="NOB46_000477"
     CDS             complement(30308..30592)
                     /locus_tag="NOB46_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HCI1057452.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(30648..32171)
                     /locus_tag="NOB46_000478"
     CDS             complement(30648..32171)
                     /locus_tag="NOB46_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI1057453.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(32164..33339)
                     /locus_tag="NOB46_000479"
     CDS             complement(32164..33339)
                     /locus_tag="NOB46_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI1057454.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(33343..33528)
                     /locus_tag="NOB46_000480"
     CDS             complement(33343..33528)
                     /locus_tag="NOB46_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057455.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(33494..35188)
                     /locus_tag="NOB46_000481"
     CDS             complement(33494..35188)
                     /locus_tag="NOB46_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI1057456.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(35185..35658)
                     /locus_tag="NOB46_000482"
     CDS             complement(35185..35658)
                     /locus_tag="NOB46_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HCI1057457.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(35727..35882)
                     /locus_tag="NOB46_000483"
     CDS             complement(35727..35882)
                     /locus_tag="NOB46_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HCI1057458.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(36016..36396)
                     /locus_tag="NOB46_000484"
     CDS             complement(36016..36396)
                     /locus_tag="NOB46_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI1057459.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(36400..36615)
                     /locus_tag="NOB46_000485"
     CDS             complement(36400..36615)
                     /locus_tag="NOB46_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057460.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(36618..37025)
                     /locus_tag="NOB46_000486"
     CDS             complement(36618..37025)
                     /locus_tag="NOB46_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HCI1057461.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(37291..38766)
                     /locus_tag="NOB46_000487"
     CDS             complement(37291..38766)
                     /locus_tag="NOB46_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HCI1057462.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGESTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(38756..39604)
                     /locus_tag="NOB46_000488"
     CDS             complement(38756..39604)
                     /locus_tag="NOB46_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HCI1057463.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(39641..40003)
                     /locus_tag="NOB46_000489"
     CDS             complement(39641..40003)
                     /locus_tag="NOB46_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057464.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(40004..40162)
                     /locus_tag="NOB46_000490"
     CDS             complement(40004..40162)
                     /locus_tag="NOB46_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057465.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            complement(40303..40927)
                     /locus_tag="NOB46_000491"
                     /pseudo
     CDS             complement(40303..40927)
                     /locus_tag="NOB46_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(40924..41235)
                     /locus_tag="NOB46_000492"
     CDS             complement(40924..41235)
                     /locus_tag="NOB46_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057466.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(41279..41572)
                     /locus_tag="NOB46_000493"
     CDS             complement(41279..41572)
                     /locus_tag="NOB46_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057467.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            41766..42413
                     /locus_tag="NOB46_000494"
     CDS             41766..42413
                     /locus_tag="NOB46_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1057468.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            42474..43619
                     /locus_tag="NOB46_000495"
     CDS             42474..43619
                     /locus_tag="NOB46_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1057469.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(43700..44005)
                     /locus_tag="NOB46_000496"
     CDS             complement(43700..44005)
                     /locus_tag="NOB46_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCI1057470.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(44030..44461)
                     /gene="ruvX"
                     /locus_tag="NOB46_000497"
     CDS             complement(44030..44461)
                     /gene="ruvX"
                     /locus_tag="NOB46_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCI1057471.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(44458..44724)
                     /locus_tag="NOB46_000498"
     CDS             complement(44458..44724)
                     /locus_tag="NOB46_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCI1057472.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(44979..45704)
                     /locus_tag="NOB46_000499"
     CDS             complement(44979..45704)
                     /locus_tag="NOB46_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCI1057473.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(46065..46135)
                     /locus_tag="NOB46_000500"
     tRNA            complement(46065..46135)
                     /locus_tag="NOB46_000500"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46101..46103),aa:Gly,seq:ccc)
     gene            46252..47004
                     /locus_tag="NOB46_000501"
     CDS             46252..47004
                     /locus_tag="NOB46_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI1057474.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            47020..47499
                     /locus_tag="NOB46_000502"
     CDS             47020..47499
                     /locus_tag="NOB46_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI1057475.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(47750..49330)
                     /locus_tag="NOB46_000503"
     CDS             complement(47750..49330)
                     /locus_tag="NOB46_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HCI1057476.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(49323..50066)
                     /locus_tag="NOB46_000504"
     CDS             complement(49323..50066)
                     /locus_tag="NOB46_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057477.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(50242..51018)
                     /locus_tag="NOB46_000505"
     CDS             complement(50242..51018)
                     /locus_tag="NOB46_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1057478.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(51266..52102)
                     /locus_tag="NOB46_000506"
     CDS             complement(51266..52102)
                     /locus_tag="NOB46_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HCI1057479.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(52113..53042)
                     /locus_tag="NOB46_000507"
     CDS             complement(52113..53042)
                     /locus_tag="NOB46_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCI1057480.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            53234..53587
                     /locus_tag="NOB46_000508"
     CDS             53234..53587
                     /locus_tag="NOB46_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI1057481.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(53661..54317)
                     /locus_tag="NOB46_000509"
     CDS             complement(53661..54317)
                     /locus_tag="NOB46_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI1057482.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            54543..56477
                     /locus_tag="NOB46_000510"
     CDS             54543..56477
                     /locus_tag="NOB46_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1057483.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(56563..57786)
                     /locus_tag="NOB46_000511"
     CDS             complement(56563..57786)
                     /locus_tag="NOB46_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI1057484.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(57780..59678)
                     /locus_tag="NOB46_000512"
     CDS             complement(57780..59678)
                     /locus_tag="NOB46_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HCI1057485.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(59672..60790)
                     /locus_tag="NOB46_000513"
     CDS             complement(59672..60790)
                     /locus_tag="NOB46_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI1057486.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(60873..61706)
                     /locus_tag="NOB46_000514"
     CDS             complement(60873..61706)
                     /locus_tag="NOB46_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1057487.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(61699..62616)
                     /locus_tag="NOB46_000515"
     CDS             complement(61699..62616)
                     /locus_tag="NOB46_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1057488.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(62843..63967)
                     /locus_tag="NOB46_000516"
     CDS             complement(62843..63967)
                     /locus_tag="NOB46_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1057489.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            64150..65058
                     /locus_tag="NOB46_000517"
     CDS             64150..65058
                     /locus_tag="NOB46_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1057490.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            65199..66812
                     /locus_tag="NOB46_000518"
     CDS             65199..66812
                     /locus_tag="NOB46_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1057491.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKKPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        19981 a        13673 c        11307 g        22402 t
ORIGIN      
        1 tatattttat gctttttttc gttcatttct cataattgaa atcgattgtt tcaatgaact
       61 ccataatccg ccttcgctat acacgagtac attcgatttg tacatgtttg cagacaagat
      121 catcaataag aatgttacgg ctacaagtac caacaaggaa atcaatgctc cacccatacc
      181 gactgtctca tttgctaagc gaaccggcat aatatatgaa gataagaatg gaatatacga
      241 agtgatccga ataacgatat tgtttggatc tgaagctcct agtatcaatc caagcatata
      301 tccgcctaga gatagataag tcactggcaa aattgctttt gctgtatctt ctgctttgtt
      361 gaccaaagag ccacataaag ctgctaaaac agaaaaaatc aaaatgccaa agatcatgaa
      421 tagaagagaa taccacaaga atggtccaat caagttatcc aatgagatac cgtctaatat
      481 atttttgacc atttccatat ctttgaattg actgtatcct ataccaaaaa taataccgta
      541 taatgccatt tgcgttaatg caacaagtaa aacacctgtt agttttccgt aaaaatgctt
      601 ttgtgcagtc gtactggaca ggatcacttc catgatccgc gtgccttttt cagaagcgat
      661 ctcttgtgca atgatctgcg catacgtcaa aataataatg aacaagacaa tcgttgctac
      721 ataacttacg acatattgga ctgtcgagtt atcttctcca actgtcattt ttccttttga
      781 atcaaaattg actttttgtc gagtcaaact tgcttgttgg ctcaagctag ctacttcttc
      841 tggtgaaatg cctaattgac ttgctcgaag catcgattgc aagccagtca gttgttgttg
      901 tatcagtagt tgtgtacttt gtcctaatga attttcgcta taaagcatcc catttatctt
      961 atcattctca gttgagacta ctaaatacgc atcgattttt tcttccgaaa gctctttttg
     1021 tgctttttct tcagaatcaa ctgctttgaa ctcaaaatca tctgttttga cttggctcat
     1081 ttgctgactg atttgctcat tatcagccaa tacgccgatt ttattgacat cactattttg
     1141 ttgagcaaag tttcctgcta cataaatgat acccagcatg ataaaaggga ctaatatcat
     1201 gatcaagaaa gaaatcgact taacattttt taaatagaca tctttggtaa taatccaaaa
     1261 cttacgcatc gatttcacct gctttcaatt tgaaaatctc ttccaaagtt ggcggttgct
     1321 ggttaaacat aggaatgtag ccgaactgag tcgcacgagt aaagatttct ttcccagctt
     1381 caggatcttc taaggtaatc tctaacgtat tgtcttcatg aaggatcact tttttcacgc
     1441 cttcgatttc ttctacttcc tgttggctta aaccagattc caagaataac ttcgtacggc
     1501 caaatgattc acgaatctca tgtacttttc cattcaaaac catttttccg tttcgcaaca
     1561 tgatcaaatg atcgcagatt ttttctacat tatccatatt gtggctagaa aaaatgacac
     1621 atgaaccatg ttttttcaat tccaatattc catcttttag caattcagca tttaccggat
     1681 ctaacccgct gaatggctca tccaaaatga tcaatttagg ttcatggatt aacgtggcga
     1741 tcagctggac tttttgctga tttcctttag acaaagattt tactttatcc gtctttttcc
     1801 cttttacctg aaatttttcc atccaaaaat cgatttttgg ttcaatctct tttcttgatt
     1861 tccctctaag ttctgcaaaa taaagcagtt ggtcttgaat cgttactttc ggataaagtc
     1921 cccgttcctc cggaagataa ccgatgacat cataatcttt ctccccaaga tgatggccat
     1981 tccataacac ttctccttgg tcttgtgtca aaaaatccaa gatcaaacga aaagtcgttg
     2041 tcttcccagc cccgttttgg ccaattagcc ccatgatttt tccatcgggg atttggaaag
     2101 agacatgatc gacagctgtg tagttcccaa aagttttaac aagatccttg acttctaaca
     2161 tttcttcact ccttcttcaa gaaatcacat atatccttag acaccagacg taagcgattt
     2221 attatttacc aacaaaacgt aaacgctctt tttgttgtac ataaaatgat aggacacttt
     2281 actttctttg taaagtgccc tttcctcatt cctgatgtaa tttatcaaat acgttttgtg
     2341 cgacattttt cggcagtccg atttcttgta attcttctgt cgtggctgct gtgatatttt
     2401 tcaacgattt gaactcttta agcagcattt tttttcgttt tggtcctaac ccttcaattt
     2461 catctaatcg ggaagcaaaa ctgtttttac tgcgtagctg ccgatggaaa gtgattgcga
     2521 atcgatggac ttcatcttgg attcgctgga gtaagaaaaa ctctggtgaa tttcgctcaa
     2581 gcggtactac agccaaatct ataccgaata gcaactcatt tgttttatgt ttatcgtttt
     2641 ttgccatgcc agcaatagga atatcgattc ctaattgatt ttctaagaca tcttttgcca
     2701 catctacttg tccttttcct ccatcgatca agatcaaatc aggtaaaggc aacccttcgc
     2761 gaatcactcg tgaatatctg cgatagatga cttctctcat tgatgcataa tcatccggtc
     2821 cgttgactgt ttttatttta tatttccgat attcttttct tgccggtttt ccatcaatga
     2881 atacgaccat cgcagccaca ggattcgtcc ccatgatatt agagttatca aaagactcga
     2941 tacgtattgg ggtcgggata ttcatcgcgt ttcctaaacg ttcaactgct ccgatcgtcc
     3001 gttcctgttt tctggcaatc agatcaaacc gttcattcaa agcaactgag gcattcttat
     3061 tcgccaattc aactaatttt ttcttttctc ctcgttttgg ttgcagcact ttcgtagcta
     3121 acaaagcttc tacactgggc ttgtcgatcg tatcaggaat caagacttct ttaggaatga
     3181 aatgctcatt ttcctgataa aactgaccga ggtaagtcaa gaaatcttct tctgcttcgt
     3241 tatagaaagg aaacattgaa acatctcgtt caattagctt tccttgtctt acgaaaaaca
     3301 cttggacaca catccatcct ttgtcaatcg cataaccaaa tacatctcga tccagtaaat
     3361 cagtatttgt cattttttgg cgagtcatga ttgtctcaat ggcacggatc tggtctcggt
     3421 attctgcagc tttttcaaac tccatgtttt cagcagcttt ttccattttc tgatggatct
     3481 ctgactcgat tttttcgtgt cctccgttta aaaacttttt cacttcatca acgattttcg
     3541 tatagacttt cggatctacg tcgaaataat aaggacacag acattgtccc aaatgatagt
     3601 aaagacaagg ctccttcgtc tgactaggtt tgcattttct cagaggaaat aatcgatcga
     3661 ggatcttctt tgtctcattc gccgcaccga catcgggata tggtccaaaa tacagtgctt
     3721 tgtcttttag tactttacga gtaatcacca aacggggata tttttcattc gttatcttaa
     3781 ggaaaggata ggttttatca tcctttaaca taatgttgta tttaggatca tttttcttta
     3841 tcagattgat ctctaagagc aatgcttcga tattcgattc tgtaacgatg tattcaaagt
     3901 cttcgatttc actaacaagc cgttccgttt tcgtattatg gctgccagta aaatatgagc
     3961 ggacacgatt ttttaatatt ttggctttgc cgacataaat gatcgttcca tttttatctt
     4021 tcatcaagta acagccgggc tgatcaggaa gtaaagctaa tttgtttttg attcgttcgt
     4081 tcatctggta ctccccttca tattcaatta aagttattat agcatgtctg tcaaaaaaac
     4141 aatccagcct gacaacgtaa ttatactcaa aaaatattaa tttgaataac cttaactcaa
     4201 ccgcaaaaaa accgaggacg gaactggatt cagtcccacc ctcagcttat ttttgctgta
     4261 agtttttata aatattgatc gatcatttga cgtagttgtt cttttgaatg aacaccaaca
     4321 gctttttcta ctacttgacc atcttttttc aacattaatg ttggaatgct catgataccg
     4381 aattgttgag gagtttctgg attttcatcc acatccattt tagcaattct gaattcttct
     4441 tcatcatatt cttgttccaa ctgatccaaa atcggtgctt gcatacgaca tggaccacac
     4501 caagttgccc aaaaatcaat caatacaagt cctttatctg tttcttcatt aaatgtctta
     4561 tctgtaatta cttgtgacat atcaaagacc tccattttta aaatctatga ttagtatagc
     4621 atttctatac ttggatagcg aaccatctgc ttacctttag taagctttac ttaaatttaa
     4681 caattgtcgc accatttccg ccttggtttg ccggtgcaaa ctcaaagctt ttgacgctcc
     4741 gatggttttt aagataatca gtaattccct tgcgaagtgc gcctgttcct tttccgtgga
     4801 caatagtcac ttgaggataa ccagctagaa tggcagaatc caaatattga tctacctcac
     4861 ttagcgcttc ttcgtatcgt tttcctcgaa ggtccaattg attcggcacg tgactactag
     4921 attcagatcg tacagcatgg ataactcgtt gtgtcggctc tttttgagga gcaacaggcg
     4981 tcagctcgtc ttcggacaca ttcattttta atataccgat ttctacttgc cactgattcc
     5041 cgtttttacg taaaagcgtc cctctttggc cgtaagtcgt aaccaacact tcgtctcccg
     5101 gtttcaacgt tttttgttct ttcgccttct tcaatacttt atttttcttc aaagtttctt
     5161 cttgatgtag atttgctaat tgggtctttg catcgatcaa ctgatgctct ttcacatttc
     5221 cttgcccaat ctgctgttgc attttacgaa tatcagcaat gattttttct gctttttctt
     5281 ccgcctctga cacgacttcg tttgcttttt tctttgcttt ttccatttct ttttcacgtt
     5341 cttcaaagaa atagctgtaa gcttctttca aatcatcgtg aagttcttgt gcctcagaaa
     5401 caaaatgacg catttccaga tattcggtct ctgccatttt ccggcgattc tctaaatctg
     5461 tgatcatttc gtttaaatct tggctctcat cattcatcaa ctgcttcgct tcatcaataa
     5521 cttctgtatc aagacctaat cggctagaga tttcaaacgc attgcttcgt ccaggaacgc
     5581 caatcagcaa acgatacgtt ggacttagtg tatccacatc gaactccatg ctggcattaa
     5641 tcgtatttgc ccgattgtat ccataaactt tcaattcagg ataatgcgtt gttgccatca
     5701 cataagcaga ctttttacca agatcatcta agattgcgat tgctagagca gcaccttctt
     5761 gcggatctgt tcctgcaccg agctcgtcaa ataataccag acttttttca ttgacttttg
     5821 ataaaatatc tacagtgttc gtcatatgag aagaaaaggt cgatagactt tgctcaatcg
     5881 actgttcgtc tcctatatcc gcaaatactt cctcaaaaat accgatttga ctttcttcac
     5941 ctgcaggaat cggtaatcct gcttgcccca tcagttgtaa cagacctaaa gtcttcaacg
     6001 tgatcgtttt cccacctgtg ttaggtcctg taatgacgat ggcttgatag tcttttccga
     6061 ttgtgatgtc attagaaact actttttcct gatcgatcag tggatgtctt gcttgtttca
     6121 agacgacatg attgtcttca ctgattcccg gcacgatggc ttttacttct ttaccaaatc
     6181 gtgcttttgc attcatcaga tccattttac caatcacata agcattgtgg atgatttctt
     6241 gacgatgggg aacaagttca gcagaaagtt cacttaaaat acgttgaatc tcatttcgtt
     6301 cagcgatttg gtattgacgc aaacgattat tcaaatccac cacttgtttt ggttcaataa
     6361 ataaagtctg tcctgaagca ctttgatcgt ggactacacc gccaaataca ccgcggtatt
     6421 cttgtttgac tgggataacg tagcggtcat ttcgcatggt gatgatcgca tcacttaaat
     6481 actttgcatt tttcccacgg acgatcccat ctaactgttc acgaacagct tgttcacttc
     6541 gccgaatgtt ctgtcttatg ctctttaact caggagaagc gtcatcagtc acgcgtccgt
     6601 cttcatcgat tgcttccttt aaacggcggc tcaaaacagg gatcgtgact aactgatctg
     6661 cccacatata caaacgtgca aattcgattt cactgtcaga aagatcatca atgaaacgat
     6721 tcaattcgct tgtcgtagac aatactctgg aaacttgtgc aagctccact ccattcaagt
     6781 ctgctccgat ctcgatccgt ttcatatggg gacggatatt ttcaagttta ggtataggga
     6841 tcccgcctcg cagacgttgc actttcaatc catcctcagt ttcttgaagc cagtttgtga
     6901 tcgtttgttt ctcactcact ggtaccaatt ctgccagttc ttcttttcct tgtgcagtca
     6961 ctacaaattg tctgaccatc tgtttgactt tttcaaattc caatgtttca aggattcggt
     7021 tattcatttt atcaccttat ctttcactat gaaaaaagag ctgtgccgga catacgctac
     7081 gcagccttct taaataaact actctgtaca aaaaacgaaa tattttccag cactattttc
     7141 cttaattcaa aatattcgtt accaaagctc atacatcttg ttggtaagaa atggcgttct
     7201 ctcaacgata aaacgagcga aactatgctc gccgaattga ttttggacca catctaatgg
     7261 aacaaaggca agtaactgca aaatcaaaaa tatagtaacg taagccatga ttagtgacag
     7321 gatgcctcct gcaatccagt ctacctgtct caagatcggc acatacgtca atccatggac
     7381 aaaaaccccc acaaatcggg taagcagcca gccaattagc aaaataatca gaaaagcagt
     7441 tcctgcataa aaagcttcat ctaggtgaaa agcaaatacc tgatcaaaaa atgctaactt
     7501 tgatgttggg gtgacagctg ggtatggaat gtataattcc aaatgacttg ctaatggttt
     7561 gtaaaaatgc tgggcagcaa taaatgacaa tacatatcca atcgcgaata tgatttgcaa
     7621 agcaaacccg cgacgtgctc cagaaaaaaa cgcaattagc aataaaaata aaatcagcaa
     7681 actcagcatg ctacgttcct ttctcttcta acttttttaa atttttctta ttttgataaa
     7741 aggatcttaa ttagaagatt tttgtttaat ttgtcctttt cgtttctcgt ttaaaatctg
     7801 ttgtgcttcc acatgatttt taatggtatg atctgcttga ccattttctt tcaatacttc
     7861 ccgagcttcg ttctcgattg cttcaatgcg tttcacacga ttttcaagct ctgtaaattt
     7921 gatcattttt ttctttaatt ctgctgtttc ttcttccagc tccaagattc tttcttgttt
     7981 cttcaattga tccgaaagcg cattgacagc catcaagatt gctgcttgtt cattatccat
     8041 ttgtggtgat aattgtttca attctgctaa ctgttcattg atcagcttcg ttacgatatc
     8101 catatgatgc ttggtttccc gtccgataat agtatatgtt tggttggcaa tcactgcttt
     8161 gtagcgtgtt ttttcgtgcg ccatacgaat catttcctcc tatttgatga aagttttatt
     8221 tagtgtacca tgaagttggt tctttcaccg ttctccacaa atatttttca catacttaac
     8281 tattatatga taaactttaa aaaaatgcta tgtctcgcaa tctcttagaa aacgaaaagt
     8341 cgtgagttgc ggtatagttt tatgtataaa aacgaggaga attttatgag caacgtcatt
     8401 atcaaagcaa caaacgacca acttagtcaa atgaaagcat actatcgctc ttatttgtta
     8461 aataaacaga ttccttatac tagctttgct gcaaaaaaag acgggacgac cattaccgct
     8521 tatacatccg gaaaagtgat gtttcaaggt acgaatgcag caatagaagc tgataaatgg
     8581 ggggaggcac aggataaaca agccaagcca gcaaaaacag cctcttcttt gccaaaaaat
     8641 atcagtcaat tatccgtttt aggtagtgat gaggtcggaa atggcagcta ttttggtccg
     8701 ctaacagtat gtgctgctta tgtgaaacgt gatcagcttg cagaattacg taaacttggt
     8761 gttagagatt caaaagagtt aaaagatagc caaatcatcc agcttgctga catcttaaaa
     8821 aaaaccatcc cctataaact gcttgtctta tctccagaaa aatacaatga gatccaacca
     8881 aaatacaatg ccgttcggat gaaagtcgct ttgcacaatc aagcgatcca tttgctgcta
     8941 aaaaaaatcg agccagaaaa accagaagcg attttgatcg atcagtttac gccggaagca
     9001 aattttaaaa aatatgcgcg tttagaaaaa aatcaattac aagaaaaact gtacttcgtt
     9061 actaaaggag aacaatatca tttagctgtt gctgctgctt ctatcatcag tcgtgccagc
     9121 tttttggaag agttacacaa agcatcagct gaagctggaa tcacccttcc atcaggagct
     9181 ggaacgaaat ctgaccaagt agcggcaaaa ctattggaga aaggcggcat gcctatgctt
     9241 gaaaaatatg ccaaacttca ttttgccaat acagaaaaag ctttgaagct gctaaaaaaa
     9301 taatggaact gtgacaaaag tcatgtcaca gtcccttgtt ccgaataaac ggtgttctca
     9361 tgccaactcc tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa
     9421 ttgctccttg tgacgcggag ttaaacggca ggctcacaac ctcttcctta aacggtgttc
     9481 aaaagcttgc atctgcgata ataagcccgg ccaaacgaaa aatatgagga gctatttttg
     9541 tttggctggg cttatttatt actgaaaata agtggtcaat gcttgtgtca aacttgcagc
     9601 aatctgctgc tgataactgt ctgttactaa ttcctttaaa tcactatcat tattcatata
     9661 acccatctcg attaaaatag aaggttgaag attttctcga agaacttgat agttcccagt
     9721 ggagattcct cttgaatcca gaggcagatc agtgaaggag tcagcaattg tctgtgctaa
     9781 tgtttcctct tgtccatagt aataatatgt cgtgattcca gttgcttcat tcgcatattc
     9841 cgtagagtct gcgtgtaaac tgataaagac atctgccttt ttttcttcac tgtagtcgca
     9901 tatatctcca agctgtacta attcatctgt agtatgggtc aaataaaccg ttgctccagc
     9961 atcctctagc gcctttttta cttttatggc tgtacttaat gttatatctt tttcttctgt
    10021 ttgttcatca ttgcttaatg ccccagtatc atttccgcca tgcccaggat ctaatacaat
    10081 cactgcatca gatagctctt ccggttttgt ttgtatattc tttgtgactt tggttccatc
    10141 ttcgagggct aaatatccag tatagccatc atttgtcttg atctgataag cattttttgt
    10201 ttcagaaaga aactccgcca gctctccgcc gtttatagtt gcaagtgggg tagttagcga
    10261 gtcatctgta tatagtgtac ggtcattttt tccgattttg attaatgtct cttgttctgt
    10321 atcatcaaat gattcctttg tctttgtaac cgtactgttc gtactgctga ccgtttgtcc
    10381 aactatcttt ttttgaccaa aaacatctat ttgaaaacag ataataatga taatgattgc
    10441 aaatacaaaa gctccaatta tttttttcat tcttgactct cacctcgtag atccagacta
    10501 agggtcaaaa cttaaaatca gcttaagtac gcaaaaaagg ggctgtaaaa gatataaccg
    10561 tagaaaataa cattactgct aaaatgattt ttttcatttt tggcatatcc tgaaatctcc
    10621 ttttgactat tcgtggtgat tcatctaccc aataaatagt ttccttcatt ctacaaacaa
    10681 ttaatttctt cgttattaaa ttaaaacact tcctggaaca ccgacataat aaataaaaat
    10741 ataccctgat aatcatgaga gaataacaaa tttgtattta tgaaaaacta cctatataaa
    10801 aaaaacaaga tataacgatc ttcgtcatat cttgcttctt cacctaacta tttttctccc
    10861 tatataacag ctttacgctt ctcctaatac accattcaaa tataaatcga tcaattgcgc
    10921 cacatttagc ggttcttcca caggtctttt cgaccgagtg atgtaaggtg ctaacactaa
    10981 gaaaaaatgc cttgctgcga tttcttttga aatcccattt cttagcacag attggtttgc
    11041 tgaaaagatt tcttcaaaag gttcacgata atttttcttc catagaaaga aaagatgatc
    11101 tcttgtttcc tttgaaagat tgctttcaag atcgtgaagc atcagaaaca aatcgaccag
    11161 atgtgtctca atcaaaaact gcgccatttt tgtcaaggtt acttgaaatc ccgtttcgct
    11221 tgtttgaacg atttctctca aagcttttcc aacatctttt aagtggtttt ctaaaactgc
    11281 cgtatatagt ttttctttat caccgaaata atgatagaga ttgggttggg tgatcccaac
    11341 tttttgtgcg atctctcttg ttgaagtgcc gagatatccc ttggacataa acaagtcagt
    11401 cgcttctttc aaaatttttt gctgtgtatc tttgttgtat cgatggacca tttttccacc
    11461 tgctttttgg ttattctttt tctttcaata caccatcttc catcataaat attctatcgc
    11521 atttgtcaat cagccgtgta tcgtgagtaa ccatgatcgt tgctttattt ttgtcttttg
    11581 attcttttgc caagatatcg actacttctc gtgccttttc tgaatccaaa ctagcagttg
    11641 gttcatctgc tagaataatg gacggatcat tgtacaatgc acgagcgatt gcgacccttt
    11701 gccgttctcc accagatagt tcttctggat acttgttgat caacttatcc acgccaagct
    11761 gctcaaataa ttcttttgct tctttttgac gatgttcatg tttgatctta tctactaata
    11821 ataactgctt ttttactgtc agaaaaggaa ccagattgga agcttgcaaa ataaagccaa
    11881 tttctttaaa acgtagttta acgcgttcac tttctttttg attactgaat tcttgatcat
    11941 tgataaatac agagccactg ctaggcgtct gcaatccgcc tgccaaagtc aaaaaagtac
    12001 ttttacctga accagaagga ccgatgattg caacaaattc ccctttatcg atactcatgg
    12061 ttgtttcttt caatgcttta actacttggt cgccatcttg gaaacttttt tctacttctt
    12121 taaattctat tgctttcatg ctcttcctcc ttcttatcca attgccttca acggatcgat
    12181 ttttacgatt gtccgaacag aaaatagtgc gcctaacaca gctactacca gcatcaacaa
    12241 gctaatgacg ccaaaaaaca gccaattgct ttggaatgga accgcatcag gtagaacaag
    12301 ggatgttccc actgttccta atagaccaag aagaatacca acaaatgata aaatgaatgt
    12361 ttgtgccact acagaacgcg caataaatcc tcctgtgatc ccttgtgctt tcattacacc
    12421 aaagatatta atcttttgca tcgtcagtac ataaatgaaa atcccgatca caatagccgc
    12481 aataacgatc aaaaatccga tcataaatcc aaaagtcaat acttgcgcat tatatccagg
    12541 taattcattg atgaatttag aaattttgat ctgttctaaa tcttcaggta aattactgat
    12601 tttacctctg acaactattg cgttaatccg tgcattttca cttgtatctt ctttttcgaa
    12661 gcggatctct tggtaagcat tgatggttgt atagagaact ggtgagacat tgaatttggc
    12721 atgatccgta aagccagtta gtttaaacgt cttgtcacta ccagataact taactgtatc
    12781 tcctacggct agaccatatt cttctttcaa actaatatcg cctactgcct catcatcgtt
    12841 atcaaaagct tttccttcaa caagattggg catgatgaat tgatttttat cgataccgaa
    12901 gaagctaaca ttgatttttc cttcttctgt actgtcttta ctagtcacga ctccaggtgt
    12961 ctgggcaaga tacgccactt tcccaccttc gacttcttct gctatcttct tagtaatcat
    13021 ggacatccct agatttgaat ttgcatcttt cgaaagcaca atcgaatctg cctcccactt
    13081 gtcgactgct gttcgattat cttgagctaa gccataagct aacccagtca aaaaaaatac
    13141 caggtaggcg atcaaaaaca tcacccctgc aactaacgca taacgtaact ttgaatgcat
    13201 aatttcattt aatgctaaaa acatttaact cctcctcctg aaataatcat tttatacaac
    13261 aattttatca cttgataaat ttttggcgaa tattatgctc aaaaaattct tccgctattt
    13321 cattatatga attttttatt ctcgattgat taatatttat tatatcccca cacaataaaa
    13381 gaccgtgata tttctcacag tcttttatct actctattgc tatttgctct cttagctagt
    13441 actttaaaag ctaactcatt gaggtagtga aaacgagagg tgtgttcaaa cagaaatcca
    13501 aaatcctcaa ctgctagctg tggaatcgta gttttgtgtt tcacgatatc cgcaagcagg
    13561 ttcaaatctg ataataagaa ttcttggctt atcagctgtc cgccaattat ttctaatgta
    13621 tccggatggt agatcagctt tgcatttact gttttgtttt cttcatcgta ttgtggaaat
    13681 agatcaaatt ctcctgaaca cgaaccggta ttttgttcca agaatggcgc ttcatcttct
    13741 gtcagcccta cagttcctaa aaagtagtct ataatgactg ctgctgttat cttttgtctg
    13801 aggtcgtaag cggttggctg accactcaaa gttagcgcta ctgctcttgc catatgtaca
    13861 gctcgagtaa ctaaaggtaa aaagagatgc cgtttatttt tgtcaaaact gactgggacg
    13921 atatctccaa tcgcatagat gtccggatca cttgtctgca gatattcatt gactatcaca
    13981 gtctcatcct catacaaagc cactttttct tttaacaatg tcgtattagg acgagtttgg
    14041 gcagaaaaaa tgaccatatc tgcctttatt gcttgagata gaagttgtac ggatactact
    14101 ttctcttctg attttttcca atcgatcaag aattcatttg gataaaaatt gatttgctta
    14161 gtttgcagct gattttgaaa actgttgatc atatccttat cgaaatatct tgataaaaca
    14221 ttcggcatat aatcaactag atgaataatg tatcctttat ttctcaaagc atctgctaat
    14281 tccaatccaa tataaccagc accgaagatc actacttctt ttgcttcttt taaagcggca
    14341 agtacttgct tagattgcac tagattttta taggtgtaga cattttcagc ttcaatttgt
    14401 ttatacaagg tgacaggaga ggaacctgtt gctacgatta atttatcata ggttatggtc
    14461 tcgttttttc cttctttgga tgcgaggatg agctgatgtt tgtctggatc aagttcagtt
    14521 actctccatt cggtgatcag ttttgcccca ctttcttgaa gagtccgcat gttatgggca
    14581 acttcagcta aactacgtat ctttcctttt aaataaaggt tgattccatt tgaaacatag
    14641 cctagtccat ctttatgatc ttcatcgatc agtaaaactt ctgctttcgg ttgaagtttt
    14701 cttagattta gggcagctgt gatgcctgca tgggaagcac caatgatcac gattttcatg
    14761 ttttattcat ccttaaattc aatttttcta aataacattc ttttaaaaat tggttcaaat
    14821 aggggaaatc ataattatat tcgttgctag tgaatacaaa aactttagcg gacttctgtg
    14881 acgggtactc tttcaattgg ctagtcaaaa tgatatcata ctgcttttct ttctcgtatt
    14941 cgactaaatc atatttgatc gtattcagca attgttcctg gatgatttct ttcacgatat
    15001 ccgccattag cctttcataa ggaagatcat aagcaatttg cagacgtaat tctaactgct
    15061 tgatcagcgt ccgcaaaata gatgcatagc gagcaaataa ttcaaagcgg gcattttcct
    15121 cgtctacttc agtaaaatca acaatagcaa atgtttgtct gaccaatctt tcacataaaa
    15181 ccaggaattg tttatcttct acttcagtta accgctgttt taatccttct tggccaaaaa
    15241 tattcatcca tcctctaaaa taggcaaaat gagcgtgatt ttgcatcact gtcaacgcaa
    15301 tcttttgcga aatctcttct ggaaaaacat aaaaagagaa atattcttct atcgattgtt
    15361 taaacgttcg attcaattga gctactacgt cgtctttgta tttttcgctt atcaaaaact
    15421 cctggacatg cgagttatgt gtatctaatg taaagttact gatcatgaaa agataaaaaa
    15481 ccaacgtttc attttgattc caaggaaagg catattgaaa gaagtaacgg gtcaaaaatg
    15541 tatggaggtc caataaaaat tgtgtcgttt gaaacaatcc aacaggaaga ttgctataat
    15601 ctggtttgga ttttttcgta cagcgcattc gcttcttcat aatggaaagc catatttcaa
    15661 atttcaatcg tccttcttct gtaatagtaa aactaaactc tttttgcagc agatctaaaa
    15721 aagtgtttcc tgataaatca ctgtattctt ttttgttttc aagataagga cgtccaaacc
    15781 aaaataattg gaaataaaaa taacaaattt gactttctgg accggtcagc cgcccgcttt
    15841 ttattttcag atgaaactca tttaaagaat catttaattc cttcactctg cgagacaaag
    15901 tagccgaact gatattaagt tccatgacaa gtttctgccg atcaaatgag ccattttcca
    15961 acagataaag aagtatctga tattttgtag aatagcgcaa gtagcaatga taataaacat
    16021 cgactgctgc tatatttcca tgtctgatta ataaaatatt cccttcttgg ataacaattt
    16081 ccaattgttt gatattttcc aagttagctt gtaaataaaa cagatcttct ttcaaggtag
    16141 cccgatcaac tgataagcgg gtaagtacgt tattaacgga aatctctcct ttttcctcta
    16201 ataaaagttg gaaaagtttg atttgccgtt gttcattttt ttcaagcaaa ctgaaaagtt
    16261 ccaagtccac tcctccaagc atttctgatt ttaacagcag aagtttcctt ctcatccttg
    16321 aaaaagagga tctgtgacag ttatcacaga tccatacaaa ttctaatcac ttagctggtt
    16381 ggcccagctg tcagttccca tgtgaccatg ccttgatacg ttgcgccagg ttgagcattc
    16441 gtactgctat ttacctctaa gagtaaacca tcggtatcgg gaaagtcaac gagaacctct
    16501 cctttagctg ttccatcact ctcataaatc aacgtgtttt gaccttgctg aatcaattgt
    16561 tttgatccag aatgattgaa gtataatttt gttccgctta attcttgacc ttgatcattc
    16621 ttaaataaag aagtcaatgt ccctgtcagt tgccaaggag acgtgcttgg aagccgagta
    16681 tcccgcacat caaaagaaaa atcgcctttt gcttcataat aacttgtctt caacggtttg
    16741 gggagatcgt taccaaatgt aaaatcatct ggtacattaa ctaatgttaa ttcttgtttg
    16801 gggacaagaa ttgttttagc agatgtttgg acaactgggt taggaagctt agcaccatct
    16861 gctaatgtaa tattgctgga aagtacagct gcctttgtca gtatgctgac ggattgtaca
    16921 gaagtatcta cagtatttaa ttgatagttg taagtaagat gaatggtatc tcctattttg
    16981 ctcaatagat ctgctgggac agaaactcct tgttgaatgc cggtatctgc gatagttgta
    17041 ccatttaatt ttaaggaacc attgatataa gtagtatttt caggaagtga gatcgtgatt
    17101 tttttgtcgg ttatcgcatc cccagatttt gttaacgtga atgtcacatt ttcttgaatc
    17161 gtatctcctg atagagcaga caggggatct cctgtctcag gttgtctgct aaggtttttt
    17221 agctgactat ctgcactcac agatggaaaa ttagccactg ttatttgagg aagagtggtg
    17281 attccagctt gttcagactg ccatttgtac gcaaaagacg gatacatgtt agtaagtaca
    17341 tcgtccacca agcgataatc aaaataatat tgccctgaag ccaatgcagg tagtgtagaa
    17401 gtagctgtat ttacaccccc gttatttgat tggatcgttt ggaaaagttg atctgtccat
    17461 cctgtcgcta atttttaggt tcctttcgaa taaagcctgt aatggatcga accctttttt
    17521 agttcagttg ctgaccaatt ggccgtgact tggtacgatg cagaagaaag gagctttccc
    17581 cactgactat cggctgttaa gtttgttggt aaaaccgttc cgtctagctt gtactgctcc
    17641 aataccttta aagcaacagg agaaagcaat ccgccttgcg catctttccc actgtacacg
    17701 atattggctg tctgattcaa tccacttgtg cttgctggag tatgagtcag tattgctcct
    17761 tgtgtaacgt tttttcctgt aaaatagttg actacgcgat caaagcgact aaatggcaac
    17821 tgatcaaaac gtccttcagt cagccccatc gtcaatgtcc gactattggt agagcctgga
    17881 aggttctggt tatttccatc cacgtattct gtggtatcag caaatgtatt atattttcct
    17941 gttgaatcac ttgttgagat gtaactattc cacgtattta tctctgcact tgcagaaaat
    18001 gcatatgctc ctggattcaa gtttccgcca gttaatttag gataaaatct acctgcagct
    18061 ggagctaaaa tcgaattgaa catacgatct tggataatat tattcgaatc ataaaaatca
    18121 acagaaaaaa cggccttttt agacatagaa ggttgtaatt tacccttggt caaaattttg
    18181 tttggactcg tatcatattt atctccgttt tctgtcatct tcgcgacatt agctgtaaca
    18241 tcaaattgaa gcgggatatc gtccacgttg aattcgcctc gcgtaataat agcaataata
    18301 tctgccaata gagtatttgt atcccacgac cccatcccaa aacgcaaggt atggcttcct
    18361 gctgataata aactaccgct agtaaccttg atgggggcac cggcaatata caagtaggcg
    18421 ttgttccagt caattgcttt taatacatca ctgcttgata catgttccgg caaattgatg
    18481 atcgccacaa atgcaaatcc ttgtgcagtg atattcacca aatcaagtac atttgttagt
    18541 ttcacatggc tttcccaatg aaaacggacc gtgccacctt tccaaggatc atttgaacca
    18601 tcgttcaaat aagtagcagt caatttaggc aattggttag ccccagttag ttggacaagc
    18661 ttcccgccat tgactgcact acgtccacca tttggaggta cgatattttc atacgtgtat
    18721 ggatcataag aaatggcagg aggcgttgct ccaacagctt ctgccgaagg tgaaaagata
    18781 aatatactta aaacaaaaag cgaagtaaaa aagaaggagc gaaaaaatga aaatttattt
    18841 tgtagcaaca tgttcatcct ccttttcctt tcttctccat aacaacaacc acgcaagaag
    18901 ccataattct ataccaatga tcaaataaag aaaacggatc ttttcttcat tcgtctccgg
    18961 gaatacgcca tgttgattag attctttata aatcggtagc tgtgtctgct gttttgatgc
    19021 gccattgact gaaccacttg gatgcggaac tggacttaga tcataaaatg taatcgtacc
    19081 tgaacttttg gtatctgctt ggactggctc ttgccagctg aagaacagca aacttgcaat
    19141 aatccctccc aataagatcg atgttttcaa cgaaatcacc tcatcatgtt gtttctcctt
    19201 ttttcttttt cttgtggacc cacaaaaaca gcaaaatcaa ccataacact agaactgcag
    19261 caaccaatcc tgcataaagc catgggaaag attgttcttg tactgcaaaa acggaatttt
    19321 catttacttt ttgtgctttt tcttttttga tcgtaaagtt ttgtgtaaat cgccattcat
    19381 tactgtcgcc tgattttgct atgatttctg cgcggtaatc gccggctttt gctttatcac
    19441 cagctaaatc aagattcaag tgaaaattcg aatttggtgc aactaaaaat tcattagacg
    19501 tattttcaat ataaagctga ttttcataaa agatcttgct cgtaaatatc aaattgctga
    19561 taatcctagg ctgaggattt tggaaacgaa gctgaacagt tggctttgcg ttgacctcgt
    19621 ccaaatctcc tgataaaagt ttcagatccg gttctatcgt ctcttgactt tcttgtaaaa
    19681 cgactgcgag attataagca atacgatttt tgatttgtgc tccttctgta gcattttctg
    19741 tttcagcttc ttctttaggt gaaacatgaa tacccgctaa tacacgtccc ttaaagcttt
    19801 ttgctgggat tttcacttct ataggtatag ttgtttctgc atgtgctgat acattgattt
    19861 cctttttcgc aatgagcaaa acgtcacgga catcaaacgg caatgtctca tctaacgttg
    19921 ggtttttttg actataatcg atcgttccac catcactcgt taccgccgga ttgacagaga
    19981 cctcaaatgt tcgttcttca tctgaagaat tgctgataat tacttctagt gtctgatttt
    20041 gttccggtgc cactaataaa tcaaaataac cgattgcttt atctatttgg ttctctggaa
    20101 ataccggttt gattccaaag tctcctgctg aatcctttgc ttggctgatt gacggaaaaa
    20161 tgaaaaatag acttaaaata gaaaaaaacg aaacaaacag tcgtttactt tgattcattg
    20221 tccaccacat cctttcaaca acaactgcgg taaaaaatcc ttcacctata gtattttcac
    20281 cgcagtttgt tgaatttatt tcatactcta tgctactggg ccagccacga ggttccaagt
    20341 caaatcagcc gtgaatgttc cagctgctgc tttcggcact ttcagtgtga tatttgctgg
    20401 atcataaaca gaaagccatg ttcccagacc ttgatctttt gctgctgtaa atattggtgt
    20461 cgctgcactt gctttactca acccagttac agtttgacta gttggtccag tggattcgtt
    20521 atctgacgta cttttaacag tggatgttcc aaaatctaat tcagcgcctt gcaaaacttg
    20581 tgaaccgttt acaaaatctg aaaccgaaac tgtcacgttc cacccttgtg cttggccatc
    20641 tgcacctaca cctcgacgat ctgatacttg gagataaggt gtatcgtttt ttgaagcgtc
    20701 tacttgatac gtttttgttc cgctttcaat ctcgtgtgta ccaaatggca attcaggaac
    20761 tacatccaat gttaaagaac ctgtctggcc agttgctgga ttttccggat ctgctggctc
    20821 tactggtttt gaaggatcag tagggttaag aggctcaacg gtatttgttg gttcagtaaa
    20881 ggtaatatct ccttttgaag tcgcttgacc ctcagcaaaa gctggtgttg ccaagccgcc
    20941 tagaagaagt gttgaaagta ataatgtccc aatcatgttc tttttcataa taaatcactc
    21001 ctttttctta gtgacctaag tatagtagag acagtatgca aaaaatcctc atgaattcat
    21061 ccgcttactt gaaattatga ccctttttgt ataaaagaga aaaaaacaat aaaatcgttt
    21121 acatgaatat tcttcctttt ttattaagta tgaaaaaata tttcaatttt attttttcgt
    21181 ttcaaattat tctattagtg acatccttga actataaaaa taggagtacg gcatcatctg
    21241 ccgcactcct atttttttcg tcatttattt cttaaataaa acgattctca cgcaatttta
    21301 tttttttgat atcttctact gtttgtgttc cagctaattg catgaccatt tccaattctg
    21361 ttttaaagaa atcaaacact tgatggactc ctgtacttcc tcctaaagac aatccataaa
    21421 taacgggtct gccaatagca acaagatcgg cacctgatgc gattgctttg aaaacatgtt
    21481 gtccacgtcg tacaccgctg tcaaacacga ttggtacacg tttatctact gcttctgcca
    21541 catattgcaa cgaatcaaac gcagcaggcc ccccatctaa ttgacggcca ccatggttag
    21601 atacccaaat tccaccagca ccagattcta atgatcgata gacatcttct tctgattgaa
    21661 cacctttcac gtagactggc aaatcagaat gagcagcgat aaattctaca tcttttggac
    21721 taagtttttg tttggaagat ttatatacag catccatcgt ttggcctact cctgattgat
    21781 aagcctgaac gatcggcatt ggcagcggga aggtaaaccc gtttctgcgg tctgtttcac
    21841 ggtttccgcc aactgttgca tccgctgtca atacgattgc ttttgctcca ttacgcttgg
    21901 ccacttcaag aatatccaaa ttgattccat tatctttgct catataaaat tgaaaccatt
    21961 gcggtgcttt ctccccgcct gcttctctta tctcttctaa agtacaagaa gcgtaagaac
    22021 ttgctgtata gatcgtccca aaatctgcta caccttttgc agaagctttc tccgccttca
    22081 catgagctaa tccatgagca gcaactggtg ccatgatgat tggtgcagtc agcatttctt
    22141 cgtcaaaatg tgtagttgta tcgggtaatt ctacatctct taatacatga ggaataatca
    22201 aacgatgatt gaatgcccgt tcattttctt gataagtaaa taagtcgcca gcaccactgc
    22261 tgatgtaacc ataaccacca gctggaatca cttgtgaagc cgcgatttct aaatcttcca
    22321 tattgataaa atctactatt ccttcatttg tacctgcttg atatgttttt tccatctcaa
    22381 tgccttctct ctataaaatt tgaatgatga acaatatgat agcgtttaca ctttttatat
    22441 tactcttcga cattgataca ggcaaataat ctgtttacat ttcagccatt ccagatgtca
    22501 ctactctgga agaaatgatt gtaataaaaa tagataaaaa accgatggga ctttgacaaa
    22561 agtagtgtca aagtcccttt ttttgaataa acggtgttca aaagccattt tctcggtatt
    22621 aagtcaaatt tatgcaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
    22681 aactaagcga ctttttcaca acctctcgat aaaacggtgt tcaatcagct gaccctcggt
    22741 attagctcaa aaaatggcaa aatatgagga actattttgc catttgtctc tctaatactc
    22801 aggtcagaac gttgacttca cagtctcttc cttaaacggt gttcaaaaac ttgcatctgc
    22861 ggtaataagc ccaaccaaac gaaaaatagg aggagctatt tttgtttggc tgttcttatt
    22921 acttgatgca gggcaggttt ttcacgacct ctgattcacg gtgtttcttt ttcatcaaca
    22981 tttttacgaa atactgtgga agactattga aataagtgtg gattgtttct ttgtgtttca
    23041 atcgtttctt gccattcttc atttaatttt ggattaccgt tttcttcctt gaactcataa
    23101 ggtcctaatt caaaaatccc agacagtatt tgattcacga tttcatatag ttcagtgtga
    23161 tcagacacat gattcttgaa gatcatctca ttatcaccac gtttgaacct cacattcggg
    23221 ctctcatgat gaacctctat gcatttttct ccttttttta actgacggac ttctgaaaac
    23281 atctcataaa tatcttctcc agtaaaacct tcagcaagcg ccagactgtc cacaagaccg
    23341 cctactgtca gttcagagat tattgcttga ttggaatcta attttaatgt atagcttgtc
    23401 gcttctacta cgccacatgc attgcaaccg ccttctgata gttcgctttt tctaatcaat
    23461 tgaacttctt tcattttctc ttcctcctct taattttcta cttatgtatt tttatcacct
    23521 gacataggtg actcctatca acgctatcat gtgctttttt cctcagaaat cctatttatc
    23581 cattccatct atcccttatt cttctacttt tctttctcta gcatataaga gatacgcata
    23641 gtattcaagc aaggattgtc gatataaaaa gaacaaatac tgctattttg atttcttttg
    23701 gctatattac atataaataa aatttatcat acctgctctt tttgactata tcatcatctg
    23761 acttctatac ttcgtttgta ttaaaactta ggaggaatca ttcatgctta cagggttaaa
    23821 cttattaaat aatccttttc taaataaagg aacagctttt acaaaagaag aacgggcaaa
    23881 atatggaatc actggtatgc ttccaagtac tgtccaaaca ctggaacaac aatctgttca
    23941 agcttatggt caatacttaa gcaaacaaac agatttggaa aaacgtatct tcttaatgaa
    24001 tctattcaat acgaatcgga cattgtttta taaattgatg ggcgaacatt tagttgaatt
    24061 catgcctgtc gtttatgatc ctgtcgttgc ggattcaatc gaacaataca acgaaatttt
    24121 cttgaaaccg caagatgctg catttctttc aatcgacgaa ccagaaaaca tcaaagcaag
    24181 tttgaagaac gcggcagatg gacgagacat tcgtttgatt gttgtgactg atgcagaagg
    24241 aatcttaggt atgggcgact ggggtgtgaa cggtgttgac atcgctatcg gcaaattgat
    24301 ggtctatact gctgctgctg gtattaatcc agcacaagtt ttgcctgtat cgatcgacgc
    24361 tggtactaat aatgaagaat tattgaataa tcccttatac ttaggcaatc gtcatgctcg
    24421 tgtagaaggc gaaacttact atgaattcat cgatcaattc gttcaatcag ctaccgaatt
    24481 attcccagaa ttgttattgc attgggaaga ttttggacga ggaaatgctg cagcgatctt
    24541 agaaaaatac gaagatcaaa tcactacttt caacgacgat atccaaggta caggaattgt
    24601 tgtcctagca ggtgtattag gcggattgaa tatatccggt gaacaattga aagatcaaat
    24661 aattttgaca tttggtgctg gtactgctgg tgtgggtatc gcaaacatcc ttttagatga
    24721 gatgatccgt caaggtgtac ctgaagaaga agcacgccaa catttctatc aagtagataa
    24781 acaaggttta ttgtttgaag atacagaagg attgactcct ggtcaaatcc cattcgctcg
    24841 caaacgctca gatttcacta atgctgatga attgacaaac ttagaagcag ttgtaaaagc
    24901 gatccatccg acaatcatga ttggtacttc tacccaacct ggagcattca ctgaagaaat
    24961 cgtgaaagaa atggctgctc atacaccacg tccgatcatc atgcctttgt ctaatccaac
    25021 aaaattggca gaagcaaaag caaaagattt aatagaatgg acggacggaa aagcattagt
    25081 tggaacaggt atccctgctg ctgatgttga atataatggt gtaacttacc aaatcggtca
    25141 agcaaataat gctttgatgt acccaggttt aggacttggt ttgattgctt caacagctac
    25201 acgagtaaat gctgaaatca tttctcaagc tagtcgagca ttaggcggaa tcgttgatgt
    25261 aacaaaacca ggagcagcta tcttgcctcc agtagcaaaa atcactgaat tttctcaaac
    25321 gattgctgaa actgtcgcaa aatcagttgt cgcacaaaac ttgaatcgtg aagaaatcac
    25381 ggatatcaaa gaagcagttg aatctgctaa atgggttcct gaatataaat ctttagaaga
    25441 ttaagatcgt tatagtaaaa gaacatacag aaactttgta tgacgtctaa aaagaaaaaa
    25501 gcgactgcgg caaaacagcg gccagccaac tcctgctctt ttgtcgcttt tctttggctt
    25561 ttttcatatg atacagaata agaaaggatc tgtaaaaatg gcacaaaaaa caacaactgc
    25621 aactgcagtt gaggaaaaga aaaaagaagg tttttggtcc acaaaaatca ccggcgtaag
    25681 tttgccactt tatttgatca tggtccttgt cctgatcatt gcaatggctt tagggaaatt
    25741 accgacgaat atgattggac caatcgcagt tttggttatt ttcggtaatt tatttcattt
    25801 tatcgggaca aaaatcccta tcgtcaaaag ttatttgggt ggtggttccg tttttgcgat
    25861 cttcgcttct gctgcgattg ctacatttgg gatcttacct gaatatgtag tgaaatccac
    25921 agaaaacttt gtcagcaata tgggcttttt ggacttttat attgctgcct tgattactgg
    25981 tagcatcctt ggtatgaacc gtaatctatt gatgaaagct tctgttcgtt ttattcccgt
    26041 tgcacttatt tcaatggtcg tctccttttt tgccgtagga ctcgtgggca tgcttatcgg
    26101 aaatggtttt gcaaattccg ttttatacat ctcattacct gcgatggctg gtggtgttgg
    26161 agccggagcc gttcctttat caacgattta tgcaaatgtt ttaggtacgg atgcttcttc
    26221 tatcatttcc cgcctgattc ctgcgacagc aatgacaaat gtcttagcta tcatcggtgc
    26281 agcattagtt gctcgtgctg gacaatcaat gccaaaattc aacggcaatg gtaaattaat
    26341 ggaaaaaggc gatcttggcg atggaaaacc tcgaactgtg aaaccttcca ttccacagtt
    26401 aggtgttggt ttgatggtat cattgacttt cttcatctta ggacaaattg gtaactattt
    26461 tgttcctaaa gtccatgctt acgcatttat gattattatc gttgtcatct gtaaaatcgc
    26521 caacctatta ccagagtatt atgaagatgc agctatcatg ttcaataact tgattgtcaa
    26581 aaacttgaca gcagctgttc ttgccggtat cggtattgcg ttgctgaatc tgaatgtatt
    26641 agcttctgct ttgacatggc aatttgttgt cttatgtctg acaagtgtta tcgcgatttc
    26701 agttgtttca ggatttgtcg gtcgtttgtt tggtttatat ccaattgaat caactattac
    26761 tgctggctta tgcaacaact cgatgggcgg aacaggaaat gtagccgtct tatctgcagc
    26821 taatcggatg gaacttattg cttttgctca aatgggcaat cgacttggtg gtgccatcgt
    26881 tttgatcatc tctggtttct tgatgcaatt actttcttag tcaaaaaaac aaaaatacct
    26941 gatcatcaag tatcggcttg gtgatcgggt atttttttga taaagattta caggattttc
    27001 aaaaatcttt tttgcatttt atcggaatga taaccgatgt gttcataaaa ttggtgtgct
    27061 tctactctgt attctgcaga attaagcctt attgtcgtta ttcctcgttt tttcgcttct
    27121 tcttctacgc cagtcatcaa agcctttccg atgcctcttt tttcagcata tttagacaca
    27181 gcaagtgcca taatattgaa cattggatcg ctaaaaatcg attcatagga ctccgcttgt
    27241 acatagccag ctgctttttt agaagtagga tcttcataaa ccaagaaaaa atttttctct
    27301 ggctccttca gcagtttctt catttgtctc accgtaacgg ttaatggtat atcataccct
    27361 aattgatccg cattgatttc acgtagtgct tctgcatctt ctaaacgcat ttcccgtaac
    27421 atccaaatca ccagccaatt tctgattttt taaaatgaat ttttttatca tagtatactc
    27481 tttttttcat ttagaacaat atgtttcagt gattttgact tgcgttagtc tagattctcc
    27541 taatgtttgt aagatgacaa aggcattgta acaattgacc aaaagaacca cgaggacaat
    27601 tacttgaaaa ataaaggtca ctttttttgg agacaaaacc ctgctaaatc ttgctcccca
    27661 caaacctcca ataacagcag cggggataac ataaaacaac atagataaat caaagcgcat
    27721 aaagctactt gttaaagcaa tcgttaccaa ttttgccagt tgagaaaaga aaatcgtaga
    27781 tagagaatat agtgttgctt cttttattgg caatgcaaac atcagcatca acaaagaaac
    27841 attgactggt ccaccaccaa tacctaaaaa actagctaaa aagcccagaa cccccccaca
    27901 tataaggtac caagtccatg acgtcaaatg aaattttggc tgatgatgct tggtgtagaa
    27961 gaacgcaaaa accaaggtca ataccgtcaa aaaaatttgg atcagctgca catgcttctc
    28021 gttttcaaat aactgtaaaa aaacttcgaa tacaatgttg ccgactactc ctccaacaac
    28081 agctccacta gatacccaac cgacaatctg ccaattcagt gatttcccgc ttgatacttg
    28141 tcgcacagtc gaaacaatgg acatcgtgaa taccgcaact gttgagtaaa aagaaatccc
    28201 tgcaacagaa tgggcgccga taagatcaag aatcggtttg atcaacacgc ctccacccat
    28261 cccggaaata gcgccaactg tgttcgccag aacgatcacc acaaaataaa tcagaccaat
    28321 catcttgtat ttcctttctc ttgtttatat cttttagcga ttgttactct tttcttttat
    28381 tatacagtaa aagaaacaaa cgaggcttcg aaagcttttc tactttttaa ggaaatttag
    28441 tgctaaacga aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa
    28501 caaaaatagc tcctcataat tttcgtttgg ttgaacttat taccgcagat gcaagctttt
    28561 gaacaccgtt taagaaagag gtcgtgagcc tgccgttcag ctccgagtca caaggaacaa
    28621 tttcaaaaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca
    28681 ggagaacacc gtttaaggaa gagactgtga agtcaacgtt ttgacctgat tattagagaa
    28741 acaaatggca aaatagttct tcatatttcg ccgtttttcg agcgaatgcc gaggggcagc
    28801 tgattgaaca tcgtttattt ggaaaaaggg attgtgacaa gacgtttgtc acaatccctt
    28861 tttttatatc ttattaattc attcttttgt tctattcttc ttcttccgcc atgaatgaga
    28921 aacccatatc aaagaactat aaaggttatc aaaacagcgt ttatgactaa atgaattaga
    28981 gttatctatc actatttttc aagcgattta aaccaaatgg catacaatat ggcatacaaa
    29041 aacttcaata agccgtgggg gtttttaaat ttcttcttgt tctttaaaat caatgagtgg
    29101 agctacataa tttgaatcca ctttttcaaa cgtcactttt tgcatcgacg aatgttttct
    29161 ttcccaagat aacgtaaata gatttgactc tggacttata aagtgtactt caccttctag
    29221 tattactttc ttatgcaaat attcctctaa taaatataga cttgctaaag catacaacac
    29281 attttccaaa tttgcttcct tataatttga agaacgacca tgttttactc tgttatatat
    29341 tttccaccaa tctggtgtat cttcaggcca cccatctcca aaaggtttta gtgaagtcaa
    29401 tgttaaagaa ttcataaccc taacaccatt atccaaacac attaattcgc tagatttaat
    29461 aacagcttta aaatcagtta tgcttttatt gctactgcta tcaaatccgc aaagttcttt
    29521 gaaaataatc tcacactccg aaccaatcgc tagtagtagt ttttgatatt caatagagaa
    29581 tgttttgaaa ttattctcat cgagcatcac aaaatctgtg gtattaataa actcattttc
    29641 taaatgtaga taatacttcc aataaaaatt tgtaaactct gctttgtcca ttaaatcacc
    29701 tcttttgaat tataacaaaa aaaacacgtc cacaacagac gtgttctttg atttctacac
    29761 aatcagcttg ccaaaaccat ccaatcagtc ctagcatgcc tgtattaaaa ttgaacgttc
    29821 atcatctatc atctttctta gtccagcatg tttgcaacca cacctacaat tttcagtcca
    29881 acaatagatt tcgactagct aagtcttgca aaattcaggc agctaaccct tcatttacta
    29941 ccttaattat actaaatacc cacaacgttt acaagtgtaa tcattctaag aaatctgttt
    30001 agctatgatc gttgtataat ctttaaacgc cgttccttca ttgattgaaa taattttata
    30061 actcttgttt ttccaagcta ctttcatatc gtttgttagt tcataatctt gatcgtatcg
    30121 aataataaac gtcaacgttc cttcaagaat ggtacctaca ctagcaagca cgtcttttag
    30181 catttgtgaa cgcacattag cccaacattc aaatacagtt tcttcactat ccaccatctg
    30241 cccatcttca tcttttaccc gttttgtctt tttaaacttg actctctcag tcaattcatt
    30301 tacattctta atgattggca taataagcac ctctcatttg ttgtactaat gcttgtaccg
    30361 ttactggtat ccgttcgctg ctggcttctt gacggttcaa ataccaatgt tgagtaagta
    30421 atgacaccgc caaatcaaat tgctgataat tatccatatc tttatccgtt gcgctactat
    30481 caatagcact ttttatatat tcgcctgctg tatcaatcaa ttgttgaata aagtcatcat
    30541 caatagtgtg atcgatccgc atactttttt ttatgctatc caaaattacc attttatctc
    30601 tcctaatgaa aaaaaggcag tgggataaac cgccgcccaa tatttttcta tacttttggt
    30661 gttacaactg gcgtaaactc aatatacact gaagcatttt gatcaatttt cttataatcg
    30721 ttgcgaacga tcactgcaag tccttgtgag tagtaatcga atttttccca ttgagtcgtt
    30781 acttgatttc tacgagcaac aaagatagat tgtgcaatat cccccataat catagggaat
    30841 gttccagctt taggattggc aaacaatgta tctgcaatca atactactgg cataccgaat
    30901 aatgatttac cactaggtgc tgtcacatcg ggttgtaaaa tgtaacgtcc atctgaatct
    30961 ttcaatgtat ctaggtggta atatccgctt tggtttagaa ttaccatttt atttaatgct
    31021 gggtctaatg ccacattgta tagttgtttc aaatcgtcca acgtagcagc cgttttctta
    31081 gtgaatgttt ttaataaatc catgatatgc ttattgtcag tgttttctac caatttcgct
    31141 aactgatctt tgacctcttg tacaatattc actgctgaat cttccacaac ctcatttgat
    31201 aaggcaatct taccagcacg agtttctact ttataatcaa ctgaagtaaa catttcagcg
    31261 tcaatatcac caatttcagc aagttcagct tttgttgcta acactgcttg ttggttagtt
    31321 gctactggat atttaccttg tccatttgat actgttttta ctgttgcata ttgagctaag
    31381 ttataatttg aacgtttcaa atcaaagact tcaccgatta cttcttcggg aacaactgcc
    31441 gctgcattta cagtagtgac tccatcacgc acttcgcctt gtgaacggat atattcttca
    31501 tacccacgca attctgtttt ttcgttatcg attaaagttt tttccatgtt attactctcc
    31561 ttttgtgctt tagaagtgga ttctaagcta ttgtttgttt gttttgcttg gttgttactc
    31621 ataaacgatt cgtaagaacg cttatttact tggacatttg atgaatcata agcgggaacg
    31681 gtcacgacac taatttcatt aagtgctttg attttatcta ttgatcgttc aattgtgcca
    31741 tcttcttttt tgtcgaatga atctaatcca agcacgaacc caaaggacat agaatcaaca
    31801 accccttttg agatattctc atacacatca tttgaatagg tcgtgtcggt tagctctgct
    31861 tcaaaatgta atcctgtatc atcgacattc aatttcaacg tacctgcttt gacactagct
    31921 agtggctttg aataatcgtg tccatataat aagaacacat ttgataaatc cacctctttt
    31981 aatgcttcgg gtgtaatcac ttctacaaag ccgcctaaat cttttgacgg ttgcccgaat
    32041 ttcaacgcat agcctgaaat agttttgccg tctgttggtt gtttttcatt ttctttctct
    32101 actttgggag aatcggctgt tagctcagct tcttctgtca gccgtttttc cttttcttct
    32161 tcattattca actggtgtaa ctccttcctg ttcttttaat tgatatttct ccaacgtatc
    32221 taaatacgta aagttcaaac ttgctagtaa acgatcgcca ccatccatgg ggggtagccc
    32281 cattttcgac cgcccctcat taatcgtgag aagtgaccct ttgacctgat ccaatacatt
    32341 ttttactttt gtttcaggat cagtctctag taactgatcg gaattaaagc ggatattggt
    32401 ttcaagtttc gtatctaatt cactcacaaa cacattaaag taatgaatca gcgtactttg
    32461 gatatactgg agattacttt gaacggtgct agaatgttca ttttcaacgc ctaaacgctc
    32521 aatcggtaca ccaaacgcct tggcaatttg ttttgtgttc caatcattgg aattgataag
    32581 cttcaaaaca tcggtgttta tttctaatgt tttgtagtcc attgtttcat caagaatgat
    32641 cgttctaaga gcattatctc cactacttga accgttggct tcttcaaact tttcacgaat
    32701 tgcgttcttt gctgatccgt ctaaatctga cttatgaacc ttcaaaatac ctgacccact
    32761 gacaccacga gtaaagaaat tgtgcaatgt gcggttgcca gcttgttgaa ttttcagttc
    32821 atcacgtaac gcataaagtg gtggtaatcc tgttaaacca tcttgggtga aatatttgaa
    32881 gtgcaaaata tcgctagact tcacacgtct ttttttatca ccaatctgat aagacaacgt
    32941 accattatct aattgagtaa ccgttacact tgagttaggt aataagtgaa tttcttctac
    33001 cttttcaccg ttgcgtttaa tctctgcaaa gctattaccg tttagcaaca tattgaccgc
    33061 caaagcaaac tttaaatgcc aaccatccat ttctgaatta ggtttctcgt ttagtaactt
    33121 caccagttca ttatcagctt gtggcatatt gtttttgacc aattgaatcg gacttgaagc
    33181 aatatcacta gcaataattc gaacggctgc aaacacatca ctatttctta atgcacgaac
    33241 gcttgtaaag ctggtggtgt aatcatccga ttggattgat accacatgtt gtaggaaagg
    33301 atctcccgtt gtattttgtc tcgctttaaa aaatgccatc ttttaacctc ccttctgttc
    33361 tgtatttagc atgaccgcta ccccaataag cactatgccc agcgctaaca agccatagta
    33421 gacatttgtt agtaaggtga tagcaaccaa cacacacacc aatccaagaa gtaaaagaac
    33481 ggtatgaatg taattagaaa gaaaattctt cacttgtata aaattcattg tctgctttcg
    33541 ctccttccgt tgtggtgaag taatccattg caaacacata ggcattgatt aatgcagcta
    33601 ttggatcaat tttgttactg ttctttgatt tattaatctg aatgccgttg ttatccgttt
    33661 ttaaaatagc gttgttcact gcatgggtga gaatcgtatt tttattgtga ataacgttgc
    33721 cttcataaac ttgttctcta aaagttcggg tcggaacgtt tagagtaatc gttccttgtc
    33781 ttacttctaa cattgggtag ttggcttttt cagctttact gataagcgaa ttagcgttat
    33841 acgggtcata acaaatcccc atacattcca aatcattttc ttgaatcaaa tcttgaataa
    33901 actgaaatac ttggtcatag tccacgattc cactttctaa ttgagtaatg gaacactcac
    33961 cagctttttc tagttctcga taaggcaaac cgtcgcgctt ttctttgtct tgaagcccat
    34021 atttggtggc tacaaagcta tgtgaatcac aataaagttc gccgttatct agcggtacga
    34081 tccatgaaac gctagttaaa tcatctgttt tagataaatc cactccgata taaacgggct
    34141 tgcctgtaat atcttgtggt tctacttcgg ttgcctgcca gtcttcagca atcatatagc
    34201 tgtcctcact cgcttgtctc cataaattga agtttttcac caatacagaa ttaaggttat
    34261 tttgtttcaa agcaaggttc acatcatctt gaatggttgg aatcattact tttttgattt
    34321 cttcactttc aaaaatcgga ttggctttga tccatttctc ttgatcgtga atttcttcgg
    34381 gatcgtccaa ttcccatatc gctataaagt acctgtcggc ttgttcttcg ccttttagca
    34441 cacgatctaa caataagtat tcctcgtaca taggaacgtt taaatcaagc ccagcggtac
    34501 taataacaca caataagccg ttcttttgtt gggtcattcc tgacttaatg acgttgtacg
    34561 ttttacgagt ttttgcttcg tgccactcgt caagaattgc ggttgttggt gcaaacccat
    34621 ctagcgtgct ggtttcacta gccagtgcca tagcgaacga attagagggc aagtgctgaa
    34681 tcttagagtt cataattttc agttgtggtc ttaaaaactt actagacttg accacgtttc
    34741 taagtgaatt agacagcata tcatagccca atttagcttg tttcaaagcg ttacttacaa
    34801 acaatacttg ccttgcttct gctggttctt gttccataat caacgcattg gcagccatgc
    34861 cacttgcgat atacgttttc ccattcttac ggctcatact ggtaaacgct cgattgaatc
    34921 gcctgtaatt cccttcttta gtacgccagc cataaagact gcctagaatg aatttttgaa
    34981 atcctaacat cttgattgct ttaccgtccg tagatggtag caactcaatg aatttaatcg
    35041 ctttggtggc ttgttcttca tcgaacacat aagggaagct atctgactta gaacgctcca
    35101 aatcgcttat atgacgctca cacgcttgga taattttctt gggtgcaatc agcttacctg
    35161 ataggacttt ctcaatgtaa tcattcatga attcatcaac tctttgaacg ggtcttcggg
    35221 ttcatcattt ttaaccttgt tcaaagctag ttttgatcgt gattctaagg tcatacctag
    35281 tgaggtggct tgttttttca aatcactcat agcttgtgat tgaacccgaa ccgctggatt
    35341 ggctttcttt actccgtttt cgcatgtgat aaacgtacct gattttctta tctcggcttc
    35401 ggctgttttc attcgagcaa aggctaaaca ataggctacc aatgaaccat aatctgcttc
    35461 actcaatgga taatcttttt ttaatgttgg tacgatacga ttccattcac ttctagcgct
    35521 cgctgccatc cagtcagggg gcgtgatatt tattaatggt tgctgcttga acaattcttc
    35581 tctagcgtcc acacggattg ctttttcttc acttgatata ttgccttttg tatcgtgtaa
    35641 tattttaggg tgtcccatgt tgtcctcctt tcagacaaaa gaaaaaggaa cgtaagcaat
    35701 taagctcaca ttccttcgtt tttcgatcag aatttttctt tatctaattt atctatataa
    35761 atgatttttc cgttctgcat ttgaatggtc acttgaccaa aatgaggtaa ctcaatggtg
    35821 cgctgtttcc ctgttttatc agtaataaca attgtatttt tcaataaatc tcctactttc
    35881 attatatact ttttcacttg tgattacaag tgtaatcgtt atttgtaatt acccttatgc
    35941 cttttcacaa cggttatttg taccaaaatg agtaggcatc gattgtcagt aagtttcaca
    36001 ctatgccccc ttaactcaaa gggtactctt ttctcgtctt tgtctttcat tggctgtctt
    36061 ggaattatgg tgtgcatggc ataaagaacg aaaattagtt tcatctaacc gtctattcca
    36121 atcatctttt agttcaattt tgtgatctac aacatcagct ttccttatca agccttcttc
    36181 taggcaatcc tcacatactg gatgatttaa ccgatacaag tatgaagcct ttcgccatgt
    36241 tctactttga tagaattgaa aatatttacc ttcgctttgc tttctttctt cacgcttaat
    36301 tgccgtttgc tttgctttat gcttcccaca atacttctgc ctataatcaa tcaatgtttt
    36361 acatccagca tgattacatt gttttttaac tgccatagat taccaaccaa agcgatctcg
    36421 ttcgtcagaa tcatcttgtt cccattttga tttgtattca atataaggcg aaactatctt
    36481 caagcacgtt ccgtctttaa aattaacttt agtgatttta tcttcctcaa aactaataaa
    36541 gtctacatct tcttgagtgt ttgaatactc aatgtgtttc tcaccatcga agtatctaat
    36601 actttccata tgcataatta ttctacctcc aataaattag ttatcaattc atcatctgtt
    36661 agtagcaaag ccaagaactt atcatggatg tttaaaaaca aattatcctc attcgatgta
    36721 agctctcgtt gtctcgctcg atcatatagg ttaagcagac aattaaattc atccattagc
    36781 tcacctgtat catcatagtt gccactatct accaatgatc ccactactag cgattgacac
    36841 cacgctactg actcctgcag ccaatcaggt tcttcttcca ttatctttaa tacttctgga
    36901 tcaaatgtgg aataatcttc tgttaccaat cccacactaa atgccagcgt gttcattaga
    36961 aaccgatcca tttcatctgt atattgaaag ttcggtgctt tgtttgttga aataatattg
    37021 agcatttact ttcctccttg attcgtaaca cgtggtaaca cctacgtaac aggtacccgt
    37081 taccactcaa tcccaacggg gacaagggtt ctagcgtttt ggtaacaggt aacgggtaaa
    37141 atccagtaac attattcccc agcatattag ctaactattt caaaagtttt aaggaaataa
    37201 ggtgttaccc cgttaccaaa ttgctgtatc ccttggggca gtaagggtaa actagtaacg
    37261 ggctaggtgt tactgacccg ttactacccg ttactttttg tactttccag ctcgattttt
    37321 attttcatag gcatttgact tattgtaaaa tcctcgtcgt ttatttcttt ttggcagttg
    37381 cttccgttcc caaccaggaa tactgctaat aatcaaggca atctttttag tttctgcatc
    37441 tgatcgacca ttcaataaat cctttgcttg tttatcaaaa acagcttcca aaatatcagc
    37501 ggtgagtacg ctatcaacta aataaaactc ttgttgcata gtagctccat tatagaaatg
    37561 ctgtaaattt ttctcattac atttactgtc aggatagttc tgataataag aacgtctcgc
    37621 ccacgctgga gcttcttccc atttatacgg gatttccatt tccaaatatt tagtgattgc
    37681 ttctttaatt ggattctcca tcttggcatc ctcttgatag tcttttgcaa tttctaagac
    37741 ttctttatct tcatcgggac taaaatagat tcgttgtcct ttatcaaaaa gcacctttgc
    37801 ttcagctaac acttgaagaa aatattcatc ctttgtttta aacggattca tctttggctt
    37861 attcttacaa ggcaaaggat aaaaacggcg gtttcctgta tcatctttca aatactgccc
    37921 atcattcgac gttccaataa atacacattg ccttgcccaa gctatgacat tccgaccata
    37981 aggaggtcta attttatcga tcttggcact gatgaagttt tttatctgtt caattttagt
    38041 tttgttcatt gaagataatt ctccaagttc aataattaca ttgccttgaa gctgcatata
    38101 atcatctttc ttttcaccta gcgaatctaa tgaatcggtg aaaaaatcat ccgtgtaaag
    38161 taatgctgga acggtactct caccaatccc ttgcggtcca tccaaaactg gaacgatctc
    38221 aaactttatt cctggtttat agatacgtgc gactgatccg actatccaac gttttgttac
    38281 ttctcgtgtg taaaggttgt cgtctacccc taaaaggtca ataaacagtg tttccagtct
    38341 aggctgttga tcccatttaa ctttttcgat acgttctttt actgggttga aaacattctt
    38401 tctagccaca tttactactg ctttgtgtat tttgttgtca tcaaaaacta cattgtagtt
    38461 ttcttcaata tatgccgtta aggcatcctc aaaactgtct tcccattctc cagcggtacg
    38521 attgatccaa ggagaatctt ttaataggtg aatgtatccg ctaaattcgt tataagcaat
    38581 tgttccagct aaattgctat cattggttaa aatcaattct gcattcacaa cactgttact
    38641 tttaatctga tcgtctttat tgcatcttaa tcgtgacatc caggttttca attcaatgat
    38701 attgtcttca cgctcgctgg cttcgggaaa gtctaaaata ctatctaatt tatgcttatg
    38761 agccatgagc tttccccctc aaatcttttt taatcatcga tcgaataatt tgattcactt
    38821 ctttatcttt tagcggtggt tcattgtacg catttgctgt ataaatcaat tctgctaaag
    38881 tttgattatc tacaccgtgc catagtaacc aaccgcataa cttagttaaa tgatcgtttc
    38941 tactaccttc gccagcgcct tgaacaatca tatctaattt ttttgctgtc cctgtttttg
    39001 ctacgggtcg gtattgagtc tttatttctt gcggtttttt tagcagtagg ttcactagcc
    39061 aatcgggagc tggtgcaata ttatttagag atacgttttc aataggttca tatgctctcc
    39121 caacacttct tgaaataatc atagttggcg ctattggaac tcctttagtg ataatatcaa
    39181 tcccgcttaa acttttacct ttatcatcac gcccgaagat atcagcaaat gcacctgttt
    39241 cttgttggat aattacacca tcaggaattt taaagaagaa atggattcct ttacctggtg
    39301 tgatttccgt ataagtagaa ggaaatggat catacattga agcaagtttt ttataattct
    39361 caacgccgtt tcgtgtttca gaatgttgat ctaggtcaac taccaccatt tgatgatctt
    39421 caagcattaa cccaatattt ctagttgcat cttccgtcca ccattcatta atttgattag
    39481 aatcgttagt tgcatcattc caaccactag agccttttat tggaatttta gttccaggag
    39541 ataagggata aattgaccat cccgactttt gtaattccgt tgctgcttga taattatttg
    39601 ccaataaacc tctcctcctt tttcaaaata ctggtataaa tcattcagac acctccatga
    39661 gcttcaactg ctcaagttcg tatttcaacc catcccgaac aaattcagca ccttttaatt
    39721 gattctgata ctttacccat gtattaaatg ttttcaccct tgcttcttgc atatcagtaa
    39781 tgtttaacca tgcggttaaa atctgatttt ttagctcgtt gatttctcga caaattattt
    39841 tgtgttctgc atgttttttg agtacataca aaactgttag tttttcattg aatgaatttc
    39901 caaagtaggt tttcccgata ttattttcta gttcagcgat cccttgatta atttcctcta
    39961 attcaaggct atcgagttgg tttaatagtt ttgttttgta catctactta tgccctccag
    40021 ttcttaattg atagtcgtac tcgtcataag cagtgaagag atataacgct aatcctgcaa
    40081 agatagctat ttttgcaatt aatggtaata agccgaaaat tccgccgatt aaaatgcttc
    40141 ctataattaa gtttcgtttc ataatggttc cctccgattt tttaatatgg tataatcgga
    40201 acaaagaata tcgggtttta tcccaattaa gttgccttta tcctgtccgc caagactgtt
    40261 atggataagg ctttttcttt gttctcgatc atgttaatgc tcctaagttg tctgcaattc
    40321 agcagaacga ttataaattt tctcactcac tgaaaactgc aacccatatt tttctttaac
    40381 agtcattaat tctactgtct catctaaaat aggttcacga tcaaccaaca tttcaggagt
    40441 catatctttc ttttttacca ttttggaatg accataaata gttgatacag ctttattggc
    40501 tatcacattc gctttaatgt agtctactgg ttttggttca gtaatagcgt ggcttaattt
    40561 agtcattgct tctttttggt gttctttgtc tagcatgcgg aatacttgaa agccttcaag
    40621 tcctgtggac tggcgtagtt ctttgatgat gtcgaaaatc cagtcttgaa atgcctcggc
    40681 ttctttttta cggcttttga atgccatgcg gtaaatattt tttttcgttg atgatgttta
    40741 catcttgtgt tctgcccaat gaatcgatga ccttactagt agtaacccca tctttaggca
    40801 aagagtgaat ggctctagta acctgtttaa gacctaacgc ttccgcaaca tctttcgcca
    40861 ctgcccacca ttcatcatta atatcgacaa atcttataat gtgtccgttc caaatttcag
    40921 ttttcattca acgtcctcca gttcaagccc tagcaagctc gctaacaact caacttgctg
    40981 atacaaaatt tcttgatact cttcaataga aagtcgttct ttaaactctg cttgtactaa
    41041 atcgttcaag ccacgcaata ctccgcttac cgttggttct tgtggtagca atttttgata
    41101 gtccatttgt tcgtacaaac attcaaacgt ttcttctagc gctttgcctt ccaagtttgc
    41161 taattctgcc gctgtgtctt ctgtaagaat tgttgataat actttttcga ttgctttatt
    41221 ttgtgtcgat tccattatta tttcctccta ttaatccctt tgcccccacg gcttgcgttt
    41281 atttttggta ttcttccata aagcgatcac attcatcttg tgaaattctt acgactccat
    41341 caactataat caactttaaa ccgttaggaa catatttctg catcatagta ttgtatgaaa
    41401 cgttcatata cttagcagct tgtgccttgt tcatatattt tggaaactgg tacttttttt
    41461 ctaataatga aagtaacgtt ccttgagttt gctctacttg ttgaacaact cgatcgtcaa
    41521 taattttaaa agctggatca tcaagcgtga gtttgtcaat ttttaattcc atatttatcc
    41581 cccctcgtta gcatacattt ctatacaaag attttaaaaa aatgcaagag gctcttgaat
    41641 acatttctat acctcttata aactcaatat accatcatac cttttcattt gcaagaattt
    41701 taacatactt ttttgaactt ttatgtttca cacatattta aatcgtgata tagtagagaa
    41761 aatatatgaa tggtggtgaa aatgtggcta gaaaaaaata ccccgaagca gtggagacag
    41821 gacaaagaat tagactggct agaattgaaa agggactctc aatggaacaa cttggaggta
    41881 aattatcccc accggccagt aaaggtgccg ttagtaattg ggaaaatggc tataatcttc
    41941 ccaataacac caggcttaaa caactttcaa aggtattaga tgtatccact acctatctat
    42001 taaacggatc ttatacatta agagatatgc atatgatgcc cgaaattaag cgaaatgtgc
    42061 ttgaaaagca attgaaaaaa actattgaaa aaaataactc tataattgat tctaatcttt
    42121 ctaatgctat caataacatc gaagaagata acctgactgt ctcacagaag atttatttaa
    42181 caaacgcaat aaaatatctt aaaacaggat ctcgaattga atttcctgac gggagtaccc
    42241 caattgctta tctcgcagct cttctaaata cgcttttacg atatgactca ttaattaatg
    42301 attcagaaaa aaatacagat gagaaaaaag agtatcaaga attttatgaa aatgatcttc
    42361 taaaagagtt cacagctctt gttactgagc taaataaaca ctattcaaaa taataataaa
    42421 ctgcctcctc caaccgcccc cacggcttgc tacactatgg agggaaaact attatggcaa
    42481 cattcaagca atatgaaact aaaaaaggta aattttggct ctatgaagcc tatcttggaa
    42541 tgaacaaaat gactggcaaa cctgataagg ttcgtagacg aggttacaaa acaaaaaaag
    42601 aagcccagct tgccttgtca cgcttgcaag tggactacga taaaaacggt attaaaaaag
    42661 cgaacaacga aacgtttaaa gaagtttatg acttgtggct agaaacatat aaaaccactg
    42721 tccgagaagc caccttcatg aaaactgaaa tcaagtttag aaagtggatt cttccaaaat
    42781 atggaaatct tcgtgtgaat gaagtcacgg taaaaaaagc ccaacaaatt gtaaatagct
    42841 gggctgaaac tactgaccaa tacaaggtac ttcattcaac ttctaagcgt atttttagct
    42901 acgctatcaa tcttgggatt attgagacta atccactaga caacgtatta atgcctaaaa
    42961 gaaccaccac taagcataaa gaaaaggtca aagtttacag taaagaacaa ctgatcacct
    43021 tgtttgatta cctaaacagc aaacctgaaa cttatcgaaa cgactttgat aaaacgttac
    43081 tacgctttct cttttatagc ggggttagga tcagtgaagc ccttgcattg aattggtcag
    43141 acattgattt tcaagaaaat acggtcacca tcaataaaac actaagccaa tccaaaaatg
    43201 gctataaaat cagtgatcct aaaactgatt gtagtgctgg ggttcttcca ctagatgaaa
    43261 gaacaatttc tatattaaaa aaatggcaga ttaatcagcg gaaatatatg ctgacacttg
    43321 gtgtaactga tccgactatg attttttgtg gtatctataa agaactaatc acacaccacg
    43381 ctatttatgc aagattgatt actatttgtg aaaaagctat ggttccattt ctcggtgtgc
    43441 atgtagcaag acacactcat gcttcaatgc tcttggacgc tggagctact atggtagaag
    43501 ttcaaactag attacggcat acaaaaatta gtcagacgat cgattgttac ggtcacttgg
    43561 caaaagaaac gaaagaaaag actgttgaaa aattagtaca acacttaaat attgactaga
    43621 tggcatacaa tatggcatac agtaaaaaat aaaaaaagga gaaaccctat catatcaagg
    43681 tttctcctag ctttatagtc tattcttctt cttccgccat gaatgtattg aatacttctt
    43741 caatcatgtc ccattctgcg tctgtttcga tttgttctaa ctcgccttct gttccatctt
    43801 cgttttcgat gtatgcataa gcttgtaatt ctacatcttc atcttctgaa acaccagcag
    43861 gatataaaag aacatagtta cgtccaaatt cttcttgtcc gtcaactgtt agtaggattt
    43921 catataatgt ttcatttcct tggtcatcca ccaatgtgat gtgttcgtgt ccttcatggt
    43981 cgtgggaatg gttatgttct gtcataagat tacctctttt cttttattat taaaataatt
    44041 gcttacctga gccgtctaaa taattttgta agatcatcac agctgctaat ttatcgatga
    44101 ctttttttcg tttggctctt gaagtatttg cctgctctac tagcatacgt tctgcctgaa
    44161 cagtggttaa tcgttcatct tgataatcaa ctggcaagga gaatagttct ttgatctttt
    44221 ctccgtatga catggaagct tctgcccttg gtccgatgga attgttcata tttttaggta
    44281 atccaactac aaaccggtct acttcatatt gtgctactaa ttccttcaac cgatcaaagc
    44341 caaactcttc ttctgcttca ttgatccgaa tgatctctac tccttgagct gtccagccaa
    44401 aggggtcact gatagcaaca cctactgtct tagaaccgac atccaagccc attactctca
    44461 taaattcact ccatgatttg agaggtagtc cttgacaatt acttccatga tctcatcgcg
    44521 ttcgtgacgg cgaatcaaat ttcgagcatc acgataacga ggaatgtagg ccgggtctcc
    44581 agaaagcaag tagccgacaa tctgattgat tggattgtag cctttttctt ccaaagcccg
    44641 ataaacaatc gctaatgttt cgctcacttc ttttttgcga ctatcgtcaa aaccaaaacg
    44701 tacggtttca tctgtaaaac ccatgattct acacctcttt cccgcaaggt aattccagct
    44761 taccttctac aaccttattt tactcgaaga aagggaaaac tacaaacaaa tattccaaac
    44821 ttccgaataa attaagaaac actatttgta tgtttttttc cttttttctg tagctttatc
    44881 aaaagtactc ttttcataaa gtatacgcta tatttctttg aatgtatgtt tttacacaat
    44941 tttttcataa tattcataaa aaattcgaat agctgctact aattttttgt ttttgttgct
    45001 tgtcctgtct cataattgat cgtgtagcca tcttgaacat tgtagataaa gacattgaat
    45061 tcaatttttt tgtcttcaat gctttctgct tccaattgca ctcccctggc taccagttca
    45121 ttcccctcaa aatgaggagt gacacggtag cgtacatgat gatttgtttc tttgatatat
    45181 gccgcaatat cattttcgtg agcaagcatg tatggagcat tcaacgaacg tgtccctgtc
    45241 atcaagtttt taatgttgtt attttgacca gtcagctgga aaccaattaa atggctgcga
    45301 ttatataacc attgcccgtc acttaatttc ttttgtttcc aacctgtcgg gtcaatatac
    45361 aaaggctctc tcttttcagt agggaacaaa tcttttccaa gcatagcatt ggcttgtcct
    45421 actctgttca atttatcaat atttgaatag ctttcccatg ttcctttgga aaggctaaga
    45481 tcctcttttg taaattccgg ctgattccca ttgatttcta tttcttgatg ttttccatca
    45541 tattctggca catccgctac ttgagaagct tgtggtgtgg aatcaaaaat agttgtaatc
    45601 tgctgaaaga tatctgaatc tttttgtgtg gtggaaacac cgaatgcccc tgcaatcaca
    45661 gcagcgacga tccccacgat cgccttggtt gtttttttgc tcatttcttt actcctttac
    45721 taacagctcc ctaaatctta acatatgttc ccctataaat aaatactaga aagaaataga
    45781 aacagcaaaa aataaaacct gttttaagat ggcttaaaaa tacaaaaaag agacggattc
    45841 ctcgtctcta atcagtcacc actctatctg taaggtattt attattattc aaaaattttc
    45901 ttcatactca agacaataca ctgatttcac aaccgcttgg taaacggtgc gcaaaagctt
    45961 gcatctgcgg taataagtcc atccaagtta aaaacataag aagttgtttt tgcttggctg
    46021 ttcttattac ttgttgcaga gcagcttttt cacaacctat tttaagcggg tgacgggaat
    46081 cgaacccgcg acatcagctt gggaagctgg gattttacca ctaaactaca cccgcaatac
    46141 aaaaacagta tacgcctctt ttattccttc ctcaagtttt tttattcttt acgcttctgg
    46201 tatgttttgt agtaaaataa aactaatcaa tcaattattg gagaagatgc tatgacggga
    46261 aaagaattag atctgttgct ggacacttgt ttactcgctg ggaaaatcat gatggaaagc
    46321 aatgcggaga tgtatcgggt agaagatacg atgagtcgaa ttgctttagc ttctggaaat
    46381 ttccgtttgg tcagctatgt cactcaaacc ggtctcttta ttggtcttga tcgtacctcg
    46441 accatccgaa tggaacaaat taccaaccgt tcgattaatt tagaaaaagt agtaaaagta
    46501 aatgatcttt cacgtaaata tgttgcttca gagctaacat tagaagaact ttactgcgaa
    46561 ctgcaagcaa tcgaccgaga ccgttctttc tttcctgtct ggttgcaaat cgttagcgcg
    46621 gcagtgatca gtggaacaat tatggtgtta tttggcggaa agatgaccga tttacctgtg
    46681 actttagtca ttggaggatt gggatacgca gcttatctat atagtttgaa attttttaga
    46741 atcaaatttt tatcggaatt tttatcttct ttattgattg gcatagccgc tatctacagc
    46801 gtacgttttg gcttaggaag caatcaggat ctaatcatta tcggatgtgt gatgccttta
    46861 gttcctggag ttcaaattac gaacgctatc cgtgatttgc tagctggaca ttatgtctca
    46921 ggagtttctc gcggaacaga agcgatgatg actgctacga tgatcggttt tgcgattgct
    46981 tttattttcc agctttttta ttaggaaagg aacacaagta tggggacgat atttattcag
    47041 ttttctttta gttttttagc gactgcggca tttgccgtta ttacaaatgt acctaggcgt
    47101 tcattgattt gttgtggtct ttctggtgct tttggctgga tgatctactg gatctgtgtt
    47161 caaataggcg gatctgctgc ttttggttca ttgcttggtt ctttaggagt agcattcatc
    47221 agcgatcttt tctctaaacg tttgaaaatg cccgtaacga ttttcaatat tcccgggatg
    47281 gttcctctag tccctggtgg tttagcttat caagcggttc gaaatctcgt tactgaatcc
    47341 tatcgagaag cggctcatta tgcggtccaa gcaattatga ttgctggagc aatcgcttta
    47401 ggtcttgtat tatcagaagt ctttaaccat aacatccgta atttcaaagt aaagcgtgac
    47461 gcaatcatga tgaaacgaaa aaaacggctt tttaaataaa cgaagtgtaa caaagaaaag
    47521 gttgtgaaag agacgttcag ccttgagcga tgacaaaata tctcacaaac attgcgacaa
    47581 gtaaccgcag gagcaataag aagtaattat gagtattaaa aaaagttttg taaaaatagc
    47641 ttctcacatt tttacataaa attgacttaa tactgagaaa ctgacttttg aacaccctct
    47701 atctgtaaaa aaggggctgc gacatgattt ttgtcacggc ccctcttctt tattcaaatt
    47761 ttttccaaaa cgttcgttga taataaacga tccatagagc ggaaagtatt agaactaaac
    47821 cgatcacagg aatattcact aaccaaaatg gataaaacaa agccaacatt ccgtataaga
    47881 cgataagaat aatactgatg atcaatgaac ccatcatagt tgcgactaaa cccaaacttc
    47941 ctgaacctct gttaaataat tggttaatat tggtccagtt cagcagcagc aaccgataat
    48001 ctctagcgaa ataacgtagt gacaataagt agcagccgaa taaagaacca aatagcaagc
    48061 tagggataaa aaacaaaggc agctgaaaag acagtccgct taataatgcg atcccaccag
    48121 ttaaaaaact ctgcaatatc catccgaatc tgaacttttc ttttaaatat tggttcatag
    48181 agattggcaa agaacggata aacagaaaat tttcttgatc caaagaaata agattgctga
    48241 taaaagaagt ctgattaact gttaagaaag ccaatgcgat ccctaccagg aaaacaacac
    48301 cgattaactt attatctaaa tcagttaatt ttatttcgcc tcctagggca aaagcaagaa
    48361 taaaaatgat tggagttaac aaggaagaag aaagaacttg cataatcaaa ttaggttctt
    48421 ttactaattg agcattgtaa ctaaataaaa gctgatgcac attttggttc tttttatggg
    48481 ttctttttat tttgaactca ctgtttgaat cagtcagttg ctctgtaagc tttggtacta
    48541 tcagctgttt tacagcaagg aaaaatccca gagccgtgat agctagtatt ccccaaccca
    48601 ataaaccttg ttgagaaagt ggctgactgg cagcatcata gaatggcaat aatatcgaaa
    48661 tcggatgccg atctgttaac tcattttcaa tagtccccgt ttgatgattc atccacatga
    48721 ttccagcaaa tgcgatcagc atcgagctgc caagcaagat actagaaact gtttttctat
    48781 gttttttaaa cactgctgtt cgagccaaac caaaaacaat caaactagcc agacaaaaaa
    48841 gaataatcaa aaatagagaa aacaaaagga ttgagataat gatagtaagc aaaatcccta
    48901 gatcagctcg ccatccggtt aaaataaaca tgactagaag cggaaaaaca aaaggaatga
    48961 tggtcaaagc aactaccaaa atctttgctg aaaaaacctg ttcttgtcca aaaggcagag
    49021 gcaaaaatac ttgcaggtca tttccttcaa aaaagatatt ataaatgact gatatacttt
    49081 gagttaaacc taacatacca aaaagtgcca cgtaataagt aaagaaacct ggcaatttaa
    49141 caaagttcat agcaaacata gcaaatccgt aaatcagtaa aaaaatcagc cctgaaaaaa
    49201 gattttgaga caaaagatag atagttaatc gctttccctt ttttcctttc tctcttgctt
    49261 tattcgtgag ctgtggatta acatataaaa gattaactcg aattaattct aataattgtc
    49321 gcttatacat acggtccatc tcctgtcgct tgccttccag ccattttcaa ataaatcttt
    49381 tctagcgttt catcaggtga gccattcaat aattcactaa ctgccccctg ataaatcaat
    49441 tcacctttct tcaaaatagc cagtttatcg cataactgtt gtgcggtatc caatacatgt
    49501 gtagaaaaaa tgactgtttt tccttttgcg gcatgagcct tcatcatttc tttcaaatca
    49561 aatgctgctt gaggatcaag tccttgcaaa ggttcatcca atacccaaat atctggatct
    49621 ggcagcaacg tgccgatcaa aatcgttttt tgacgcattc catgtgaaaa acttgcgatt
    49681 gtttcatttt gatgactata catatcaaaa agcgctgtca attctgctaa acgcttttct
    49741 tttttttgtg tgtctaattc ataggcagct gaaatcaagt cccaatattc tccagccgtc
    49801 aattgtaaaa aaatatctgg ggaatcaggc acataaccga ttttttgttt gatactcaat
    49861 cgattttccg tcaatttcat tccatctact aaaatcgttc ccgatgatgg ttcaataata
    49921 ctaactaaac ttttaatcgt agttgatttt ccggcaccat tatgtcctaa aaatccaaaa
    49981 atttcccctt gtcttatcga gagagacaag tcttttaatg cttgtttttt cccgtaactt
    50041 ttacttacat tgatgaattc aatcatttct gtactccttt tgtttgttat tactttttat
    50101 tgtacccttc gttattggtg gagtaaatgt caaaaagagt gcataacaaa aaaggataga
    50161 aacgactagg ctgctacttg ggttgttctc ttctacagga aaacactctt ctaacaggta
    50221 agatatgagt ctttgttttc tttaaaatga ttcattttct atcttttctt gcataaaatt
    50281 ctttagttta tcaatacttc tctttcccat ctctagttgt tctccatttg caaatgttac
    50341 tatttcgttt actctgctaa tagatgtaat gttttcagta ttaatgatat aagcttttaa
    50401 atctttacat aaatactcat attcgagtga ttttttatat tttttaattg tgccgtttac
    50461 gagaatctct tcatctttca atactaggcc tattttattt ttataacctg gcatgctcat
    50521 tagataaagg atttcatcgt aatggatata gtgatcgcta ttaccataac ggacagttgt
    50581 ccaccttttt ttcgtagcat gttgaacagg atagttttct ttttctttca ataagtaact
    50641 ttggatgctt tttttatttt tttcataagt gaattctttt atcaaataac cactaggcgt
    50701 aatctttcga ttaataacag ttattgcttt attcggatga gacgttagat aaacaatttt
    50761 acacttttca ttcttttctc taagcatttc gcctagttcg ataccgctat aataggcgtt
    50821 caaatcgatg tctaggaaaa aaatatctga ggaatagatt tcattatttt taatgaattc
    50881 aacaaattgt ataacgttca atccctgaac gatctcaaat ttccaaggac ttaataaaat
    50941 tctggattct tccaaaattt ctactagcat tttttcaaaa accaaactat catccaaaat
    51001 aaatatacgc gttaccataa aaagtacctc cactcgatat tttactatca aaatcatttc
    51061 atacaacttt tcaacataca tgttaggaat aaattgtaat tctcttcaca atcttttcca
    51121 acacctttga aaccgatatc aaatactttc aggatgctgc ttctaaaata aatatcaaac
    51181 aaatgaatac atcatgcaaa aaaagccaga caaccgacgt ccttgcgtgt cagctgtctg
    51241 agctatgttt atttattttg ttcttttaaa aagaacgata cacatactga tttttcggag
    51301 cagagacttt ctcagcgttt gtaacaacta cagatgggat ttcacgcttg aatggttgat
    51361 aatagtctga ttggatggtt ccttctattt tataccattc atcattttta accgttactc
    51421 cttccggcat atgcgtcaac aaaccaaaga ctcctgaatc tgccacacaa tggataatgc
    51481 cgaatcggaa caagaagata tctgtattgc tatcgttcgg tgtttggtaa acaaatcctt
    51541 catagctgat ttttttgcca atgaattcgc tagggtaatt ataaattagc tccataactt
    51601 ctaaatagtt ttcatctgtg atcttgatag tttgcttatc cccatacttt tctttcaact
    51661 cattcatttg gtctaagtag tctgatttgt tgaaataaat actggtatcc ggctttaagt
    51721 attgtgtctg catctccgga tcccctactg attctttact tactgggaaa ttaaatcctt
    51781 tggcttctac gatcgtagtg tcgagactaa ctgttggaaa caacgtcccc acgattactg
    51841 gcaaagctag cagtacataa gcgattccac gttgataagg ttttgacaac ccatggtcat
    51901 gatcgtgctc gtgtgccttt tcttctgctt ttccgttttt gacccacaaa tacagctgaa
    51961 ctaaagccaa aagagcagat aaaatcattg aaagaatagc taagtagcga taatggacat
    52021 tgatatattg atcgagtttg ccagaaactt gcaagtacat catcaattcg aaatacccag
    52081 ataaaatcaa aaaccgcagc atattttccc tcctaaataa ataatgtgaa tccaataacg
    52141 ctaagggcaa tcagtccgat cagcgataaa ataaagcgtc ctgtaaaata tcgtttcatc
    52201 atcagtagat ttttgatatc gaccattggg ccaaagacca aaaaggcagc tacaggtgct
    52261 gtgccgaaca gacttaacaa agaagatcct ataaacgcat ctgcttctga gcaaagagac
    52321 atcgtaaagg ccaataacag catgatgata atggctaaaa tctttgttga gccgagcgtt
    52381 agcataattc tagttggtaa ataagtctgc atcgcagctg cgattaatcc gccaatgatc
    52441 aaataacgac ctgtatcaaa aaattcgtcg attgaatgtg tcaacacatg cccagtttga
    52501 tggatcagct gattttttgg ttcattcttc tcactttgtt cttcttcatg gacatgatga
    52561 tggtgatttt ctgctacttt agacgtgatt ttttctttca atacagcgtc tttttgaaaa
    52621 taggcaagcc agacaccaat cacaagggca acaaaaaagc tgcctatcac ccgccagctt
    52681 gccatctgcc aagaattgcc aaatgcgata aaagtggaaa aaatcacgat tggattgatg
    52741 atcggagcag tcagcataaa agcaaacgct gtgtgaactg gtacgccttt tttaacaaat
    52801 tgatgaacga tcggtacgat gccgcattca catgaaggaa agaaaaatcc taagatcgaa
    52861 ccagtaaaaa tagagaagat acgattttca ggaagccatc tcttcacacg ttctggggtc
    52921 aaaaatactt gtaaggcgcc tgagataaga cagcctaata atacgaaagg taatgcttca
    52981 ataacgatcg ataagaaaat cgtactcatc tgcaaaaccg aatttggaat aaaagaaaac
    53041 atgagtttcc tcctttttat ttctagttca ttcgctttgc aaatatacgc ttttattcaa
    53101 aaaaaacaag ttgctctgta aatttttaca caactcttat tttttaccaa agcacttcaa
    53161 ttgacttttt ctgttattcc cattaaatta aggtctcata catatcactt ctatcataaa
    53221 agggagaata aaaatgaaac aaaccactaa cttgactgaa gttcaagaca tactgcaaca
    53281 gtcatccgtt gccgtcattt atctttcgat gcctaattgc agtgtttgtc acgctgttcg
    53341 tccacgacta gaggaacttc tcacacatta tgatattccg gcacttcatt tggatgcatt
    53401 tgaaacacca gaagtagcta gtaaatttga agtgctgact gcgccagttg tcctgatttt
    53461 tcatcaagga aaagaagtct ttcggcaagc acggttcatc gactttaaaa aaatccgtta
    53521 tctactagat gaactgacag cagaagatga ttccctttct tatgaagaaa tcttccgaac
    53581 aaaataatcg ttgtccaaac agaaaaaagc gattgaacaa gtgaaagttt tgccttcatt
    53641 tgttcaatcg ctttttattt ttattctgct gtattttcgg aatgcgcatt tgcgtcagaa
    53701 tgcaagaaat agatcaaggt ttgcaattca ttcgtcaaat caacattttg gatcaataca
    53761 tctgacggag cattcaatcg agcagcggta aagttcaaga ttcctttgat tcctgcttcc
    53821 gttaactgat tgactacttc ttgtgctctt tcagcgggta tcgttaaaat tgctacttcg
    53881 atttgttgga tcttgatttg ttctgacata tcttccattg gataaacggg gataccgtct
    53941 acgatgcgcc caacgatttc ctcattcaca tcaaaagcac aactgatacg tatgctatta
    54001 ctttgatgga atttgtattt tagtaaagca cttcccaagt tccctacacc gatcagcgca
    54061 acatttgtca attgatcgtc gtttaatgtc tttgcaaaaa agtgcataag atcttctaca
    54121 tcataaccat acccacgttt tcctaattcg ccaaaataag aaaaatctcg acggatcgtt
    54181 gcactatcta cttgaacggc ttcacttaat tcagttgaag acactttttt ctttccagca
    54241 ttatttaaaa tccttaaata gcgataatac aaaggcagtc ttttagctgt cgcctttgga
    54301 ataatatgat ctttcacgaa atgacctcca cgtattgtct aattacatct ttgatttctc
    54361 catcatagca gtatttatag gaaaaaatca attccattgc tcagatattg tgaaatttta
    54421 ttctttattc atttatttat catttctgca aatctcgcag tataatggaa tttatggtag
    54481 actactaatt gaaaaatagt tttttatttg aggagaattc acaaagtaga aaagaggatt
    54541 ccatgatatt attacaagcc aatcagattg ctcgccattt tggtgcagaa gtcttatttg
    54601 aaaacataca tttagaaatc agtacaggcg ctcgtgtcgc tttagttggc agaaatggcg
    54661 ctggaaaatc gactttatta aagatcattg ctggaattga agcacctgat gaaggaaaga
    54721 tcgctaaaaa taaaacagcg actctcggat acctcgctca ggacacagga cttgattcca
    54781 atgaaacagt ttggaacgag atgctgaaag cttttgaaca agttagacaa atggaagagc
    54841 ggatgcgcga gctagagatt ttcattagcg aaggtacgcc agacacacct gcttatagtt
    54901 cttatttaaa agaatacgac cggctgcaac acgatttttc agatcgaaac ggctatggtt
    54961 atgaaaatga aattcgttcc gtattgcatg ggtttaaatt cgattcttca ttttatgatc
    55021 agaaaatcga tactttatca ggcggacagc gcacacgttt agctttagct cgcatgcttt
    55081 tgcaacaccc tgacattttg attctagatg aaccaacgaa ccatttagat atcgagacac
    55141 tttcctggct tgagaattat ctgcaaagct atactggtgc attattgatt gtttcccatg
    55201 accgttattt tttagataaa gtagtcaatg aagtctatga attaagcaga agaaaaatgc
    55261 gccattacaa aggtaactat tcgaaatatc tagatttgaa agcagaacag ttagcaagtg
    55321 aatggaaggc ttatgaaaag cagcaaacag aaatccataa attagaagac ttcgttgctc
    55381 ggaaccttgt tcgcgcctct accacaaaac gagcgcaaag ccgcagaaag acattagaaa
    55441 aaatggaccg gctggatcgt cctcaagggg atgaaaaaca agcaaacttt ctattcagta
    55501 tagaaaagcc ttctggaaat gtagtcttgc aaatcgaaga tgccgctatc ggatatgata
    55561 atgtcacctt atctgaacca atcaatctag atatccgtcg tcaagaagcg attgctctag
    55621 taggtccgaa tggtatcggg aaatcgacgt tgctgaaatc aatcattcac cagatccctt
    55681 ttatccgtgg aaaagaaacg ctagggacaa atgtcaccat cggctattac gatcaaggtc
    55741 aagctgatct gcatacaaac aagacgatcc tagcagaatt gtgggatgag catcctacca
    55801 ctccagaaaa agagatccga agtgctttag gtgctttctt attttctggc gaagatgtag
    55861 aaaaaccaat ccctctgcta agtggcggtg aaaaagcacg ggttgcttta gccaagttag
    55921 cgatgaacaa agaaaatttt ttgattttgg atgaaccaac aaaccattta gatattgaca
    55981 acaaagaagt attagaaaat gcattgatcg attatgacgg cacactgctt tttgtttccc
    56041 atgaccgata tttcatcaat cggatcgcga caaaagtcgt cgaactctct gaaaatggca
    56101 gcaaagtcta tctaggagac tatgattatt atttagagaa aaagcaggaa gaagaagaaa
    56161 tcgccgaatt gttggcacaa gatgagccag aatctgctcc tgctcccacg aacaaatctg
    56221 attattacca aagcaaagaa cagcaaaagc ttatccgtag ccttcaacga aaaattactc
    56281 aggttgaaga agaaatggcg cggatcgatg aatggatcga tcagttggaa caagaaatgg
    56341 tcgcgccaga aaacctggaa gatcacgtaa aactcaatga gctgaaccaa gatttagaag
    56401 ctgctagaca agatcaagaa acaaaattga cggaatggga agaactaagc ttggaattag
    56461 aagaatatga aaattaacga aaaaaccaaa acagaaacca ttcatgctgt tttggttttt
    56521 ctttttttat tttatcaaac aaaaattcca tatttacctt tttcaccaat aagaagacca
    56581 attactagtc attctcacta aagcttctaa ataatagtaa tcaccccaaa tacaaggtgt
    56641 atttacccca ttatttttgg gcttattata aacagactgt gttaaaaagc catcttcttc
    56701 ttccgttgta gcatatcttt ctttcaattg tcgcataatt ttccaaacag cagactggta
    56761 taagttcttt tctgttttgt ctaatagacc tgattctatt aattctaata atccacaaac
    56821 catgatcacc atactagatg tatctttttc ttctctgcta gaatcatcaa agatcaaatc
    56881 ccaataacaa atggtatctt ctggcaaccg attcataaaa taattggcta atattttgct
    56941 taaatcaaaa tatttttgtt ctttcaaata acgataactt aatgcaaaac cgtaaatccc
    57001 ccatgcttgg cctctagccc aacaggaatt atcactataa ccttgatgcg tacttccata
    57061 tcttggtttt ccatctttga catccatata aaatgtatga taagttgaac catcttctct
    57121 tactaaataa tctgctgcat tttgaatatg agcctgagca gcttttttat atttttgatt
    57181 tccagtttct tcactcgccc aatacaataa tggaagattc atgcaacaat ccatgatcat
    57241 tctaccttgt tgtgaaggat cactaggatc tccccaagct tgtataactc ctgccttctc
    57301 ccaaaaacgc tgaagtaatg tttctgcagc atcaattgaa gcttccttca tttttcgatt
    57361 tcccgttatt ttataatctg ctacggttga taaagaatac aaaaaaccaa gatcgtgatg
    57421 attagtgata atttgacagt caatcctgtg gataaaatct atatctgctt tttcagctgt
    57481 ttgttgaaat aaaggatcac ccgtcttctc aaataacaac caattaattc ctgtccaaaa
    57541 tccttctgtc caaccaatat tgtctcttaa tggataacgt ccttttatag gacactcgct
    57601 tgggaattga tactgactgt tactgatacg tttgattaac ctctccgtgt gtctgcgaca
    57661 acgctcgatc tcattattcc attctttttc cattaattct ttataacatt catttatcca
    57721 tttttctgga tgtattatct cttcaaacat cactttatca agcatttccc caccagcctt
    57781 tagcataatt ttagtctttt tttattgttt ttattttgga tagttagccc ggttgtccca
    57841 tcaaaatcaa ttttgggacg attgttccat acttctaaac tataatcccg atcttgatga
    57901 gcaaccactc ctgttccgag ccaatgggtt ccttttccaa atgtaccctc taatccagga
    57961 ataaaagtgt tttcccatgt catcaagttt gtattgggca aacccataat agctgtggat
    58021 tttcgtttaa tagtatcgtc acttaaacag ataatacctg aaaagccagc ttcactcacc
    58081 ctatagtttt ccttgtcttc ttctatgatt attccttctt tctcaggaga acattcaata
    58141 gcaaaccctg tctcatatag aacatattct gtatctaatt ctactttgtg tacgcgaatc
    58201 tgccagcctt caaaaggaat aagccaagtt ctgatttttg cctgtaaagt aggttcccat
    58261 gtagaggcaa gtacctcttt cttacataca atgtctcgta cattatttcg aacgatgaac
    58321 tgtccatagg ttttgatgct ctcattctta aaactggtcg tgatatatgt gtccgctcgc
    58381 tgaatcccta gcattgaatc cattgccatt tctgctttca attgattcgc tcgcggtatc
    58441 gaaaaaccaa attgactaga ataagcaaat tttaaatatt tttcattggt caatgtatgg
    58501 aaatttggcc ctaattgtcc cgcattcaaa aaaaatgtat gtccattatc atgttgtatg
    58561 agcaaattgg cttctgaaag aagtttagtt ccttcacgaa taggcatagg catttcttta
    58621 gccgtccaat actcatggtc ttcaggtagc gccaacaata aaaaaatctt attcagccat
    58681 aatggagata acgtactatt atagggttca gtcaatgtca attgagggta ggtataacca
    58741 atattcagga tacctttttc atcaaatatt tctttttgca tccaccatct tatattccga
    58801 ttgactaacc ccttgatttc acctaattta aaaggcaaaa gatcggccca caacatagct
    58861 gaccaaaagc ttgaaactgc aaaacgataa atcatgcttc gaccaaaagg cacatttgca
    58921 ccatcttccg caaaaaaatg aatatagtct ctagaaaaat caatagctcg gttcttatat
    58981 atctggctaa tgggcttttc tggttctagt acgctataaa tcaaaccata ataatgaaat
    59041 gcaaaaggat tataataatc ttggcgacct cttgaactgt ctcgatacca gccattttga
    59101 agataacaat tttctatatt atcaaatgct tctttcagtg ctgattcttt aactggataa
    59161 ccaaattttt ggataattgt tccgacaatt atcttaaaaa attgccaatt accatctgca
    59221 cattcatatt caaaaatttg cgagaaccaa tgaataatct ggcttttttc tcctgtatct
    59281 aattttttcc ataataattg ttcatgatga tataacgcta ataacattgc gggcatttct
    59341 accatacgct ggtctctttc atgtatttct ccccaataat cgggatggga aggatctgtt
    59401 ccagctttta ttcctgatag aattaatttc aaccatcgtt catctaattg gtcaattgcg
    59461 ggccccgctc cccataaaac ccgagagaat ccttccattc ctgcaatttt atttccatat
    59521 cctacccctt gatgtatata atcaatttgt gcgccacttg ctcgataaaa cggctggagt
    59581 ggttgattta tctttttaaa taagtcaaag taatcctgtc tggtccttaa tagtggtact
    59641 ggatgtttca ttgtattttc tcctcttttt actaccaaat agctaattcc gactgttcta
    59701 atcgaagtaa gccttcaata aaaaaataat cagaatagat cagtggcaca ttataagtca
    59761 gttctctatg gtatgcttct gctccgcctc caatgatccc atcttcatcc atattccaat
    59821 ttgcatagtg cttttctgtc ttttggagta tattgatagc agcttcatga tacatttttg
    59881 atcgtacaga ggaaacatat cctgctaatt ccagaagacc gcatgcagcg catactccag
    59941 cactggtatc aatattcgaa tcttttacag caaaatcaat gagaggaata taaccagttt
    60001 tttcgatttt ctgaataaaa tttactgcta tcttttctgc tatagctaga tagtacggat
    60061 tttttgtgta acgataactt aacgcgaatc catataaagc ccatgcattt cctctgctcc
    60121 aacaagaatt ctcattgtat ccttgcccgc caagtaaccg aatatatttc cctgattctg
    60181 catcaaattc tgcgatatgc ccggttgatc catctttcct cactagatac ttagctgttg
    60241 tatctgcatg ctgccgagca attttagaga acctcggatc accagtttcc ctcgaagccc
    60301 aatacagtaa tggtaaattc atcatactat caataatcat ccaaccaggt ttatggtcat
    60361 tccatgctac taaatagttc cctgaaatat tatagcgtcc agcaagtacc gtagctgcat
    60421 gtaaccctag ttgtcgacta tgtttgtttt gagactgttg ataatgtgca atagccgatg
    60481 gtaagaataa aaaacctaca tcatgatgaa cgtctgaaaa atggtacagg gcagattcta
    60541 ataattgttc ttgttgtatt gctgcctctt tgaacttttc tcgttttgtc ttgtgaaaga
    60601 gctgccataa aataccactc caaaaaccat tggtccacca gtcgattcct ctgtccttta
    60661 ttacgtctgt atattttccg ttgtaagaaa tatatggaat tttattcccc attctgtcta
    60721 attccgcatc tatcttttca gaagctacat tcaaaatttt tcttgaccat tccttcgtct
    60781 gttcattcat ggatatcccg ccattctttt aatttttatg aatgtggagt tgctcctaga
    60841 acgaactaga tggttaacat tcgttatttt ttttacttat ttgcagctcc aatgtcattc
    60901 tccttaaatt tagactgcgc ccacacataa atcaagacca ttgggatcac tgaagttgct
    60961 aaaattagca taattgcgcc ataattaatt ggctcacctg tactagaaac cgtcatattt
    61021 ttgataatta agggaaccgt atatttatct ttatctgaaa gcatgactaa tggaaataga
    61081 tattgattcc aacttcccat aaagataagt aaaccactag taataatcgt aggtgataaa
    61141 atcggtacag cgattttcgt aaaaatcacc cactcattgg caccatcgat tctggcagcc
    61201 tccatcagtg ctgtaggaaa ttgactgcta tattgtcgca tcataaacac tgaagttgta
    61261 ctggcaatcg aagggatgat cacacctgca taagtattcg ataatcctaa acgactcata
    61321 atgtaaaata aaggaatcaa tgtggtaaaa aaaggcacca tcctagatag cataactgta
    61381 ttgaacaaca gtttattccc cataaaacga tactttgcta atgcataacc cgccattgta
    61441 gaactggctg tagctaaaac tgtactgatt acagcaataa caatcgaatt ccaaataatc
    61501 aagggataat tatatctcgc catgatggct tgccagtttt ttaatagcat atccccaaac
    61561 ttgaaattga ttccgccact taaaatttct tgattacttt gcgttgaagc tacaatcata
    61621 tataaatatg gcatcaaaaa tattaaggca ccaaacacaa taatgacgta cgtaaaaatt
    61681 ctgctttgta tcttttgttt agtcattttt atcacctccg aatttaaatt gaatagccga
    61741 taatataaca gatacaaaca ccatcgtcca ggcaatagca gaggcttttc caaaatcaac
    61801 catttcaaaa cttgttttat ataaattgac tcctacgacc aaagctgaat tttctggtcc
    61861 attggaagtc ccaaagaata tatttgggat attgaaatta cccaagccat tgatagtggc
    61921 taaaactgtg gccattaaaa tgattggctt tagcatgggg atcgttaata aaaagaattg
    61981 ccgaaatttc gatgctccat ctatttcagc actttcgtat atctctttag aaatcccttg
    62041 aagaccagct aaaaataaaa tagtgttata tcctacacta agccaaatca tcgtgatgat
    62101 cattgatatt cgtatccaaa aaggatttgt taaccactgt acaccgttaa ttcctagcgc
    62161 attcaaaaat ccattgaata acccagtcgg attgaaaaaa gtcatgaata cggaagctac
    62221 agccaccgtt gatgtaatgg ttggaatata atagacagtt ctaaaaaatc cttttccttt
    62281 taactgtgct gaattcaata aaacagcaaa gtaaatagct aatagcatcg ttattggaat
    62341 tgatcctgcc atgataatca aaacattcgt gtaagattta ataaacaatg gatctcggaa
    62401 gatagctaga taattgtcaa atccaacaaa ttcaaatgag tagccaattt tcataaaact
    62461 aaaagcaaac gagataatga tgggaatcaa aatcgtcaca ataaagaaaa taacaaaagg
    62521 tgtgaccaat ccataagcac tttttttatg agacgtatct gttgcttttt tcttgctgtt
    62581 ctttattgtc ttgcttggta acgaagattg catcatcgtt aagtcctcct aatatttttt
    62641 aatcaccagt taattttacg ccgtacttat gagcaaaatt ttctgcttct tttagatatg
    62701 aattttcaaa atcacctgtt tgccaatagt tatatgcagc ggtagtcaaa taagacgtag
    62761 catctgaata agtggctggt aaaacagtat ttgatgtatt ttcattgatt ttattcaata
    62821 gttcatagta tttttgtcct ccttagtagt caaacttttt ctcagctgct tctgtttgat
    62881 aggccaatga gttagatgta gccacgccca gctccagtgc gttggctaag cattcttcat
    62941 ctgtcagcat aaatgtaaga aattgttgtg ccacttgtgg atttttggca tctttaggga
    63001 cataaaaact tgatcctcct gatactgcac cttttcctgg attttctttt gaaaaaggaa
    63061 tcagtggagc catgcgccat ttgtcagatg catcaggaaa attcaaagac atattcgtag
    63121 cataccagcc gccagcaaca aacattgcag attcttgaaa tgctttctca gcatcttgtg
    63181 caccgtagaa atgtacaata tctgagtcga tcatttcttt gattaacttt gcagcatgtt
    63241 tcgcttcttt agtattcaga cggatatttc cttcttcatc aagcaaagat tgattctgct
    63301 gggctagcat gttgataaac aattcttggt ccccagattc tggcaaggca attccaaaac
    63361 taccagtttt ttcttttaat gcttttgcca cctggatata ttcttcccaa gaactgattt
    63421 cttcaaaatc tacacctatt tcagcaaatt tttttggttg ataataacaa agtgctgggg
    63481 taaaatcact agcccaagga ataatcgttt cattactcgt ttgttgacgc aaaatattca
    63541 atttttgatc ataaaactga tcgccatatt tgtcataaaa tccatattca tcagcactat
    63601 aaaaagcatc ttgaaatttt tccagcacac ctgctgctga agtgtctgcc atggagataa
    63661 tatccggcat atcttcgtgt gttaccaatt ttggggtgat catttgtact gttgctgttc
    63721 ccgaagctac attcacaatt tttaagtcaa tatttgctcc agttttgcgg ttatagattt
    63781 ttgcagcatt ttcaacatag tttgtcagtt tgccgtttgc gacatatact tctaatgtag
    63841 tggctttttt tatcattgga tctgcgatgt ttgctgttac ttcttcgtta gtttttccac
    63901 atgcacttaa gctgaataat agggtaatgt ttagcaaagc tatcaccaat ttgtatcttt
    63961 ttttcatgtc tatcccttct ttcttttcaa gttcttatat aaaacgcttt cacttatgta
    64021 tattaacgga attagtaaca caaatattta tataaaaaaa tattttactt gtcgttttgg
    64081 cttttcattt ttgttataat agtcattaat tataaataga aagcttttta tataaaaaga
    64141 gaaaggaaag tggttctttt gttaacaaac aaccaatcct ccaatcttgt caaaaaaaca
    64201 ctaacctatt ccatagatac ccatcttcat ttatctgctg ctccctattt tcgactacta
    64261 ataaatgaaa gcgctaattt atatgctgaa tttgcacata aatctataga actagataat
    64321 ccttcccttt tattcattga taaacagcaa gaagtccaaa tcttttctac tcaaaaggaa
    64381 acacaaactt ttatcattat ccagttttat tttgatgagc aattattagc acatattacg
    64441 ggacaatctt tttctataga tcaagaaata acatctatca ttacttttct gaaaaatgaa
    64501 cagttcaaaa ttgattatct aaaacatagt aagccagcta tttcctatga tcaggaaatc
    64561 aattcttttt tcatactatg ccaacagatg agcattcatt tgctttcctt attagttact
    64621 tattgtctgc aaaaaattca attgtcttcc ttaccaaggc attatcaaca ggaacttgct
    64681 ttattgacaa taccttcaaa tgagaaagtc attcctaaaa aaaagcatat tctttattca
    64741 gatgaattag ttgatccaat catacgatat ttagaagaac atctttcaga aaattttttg
    64801 cttgaacaat tagcccaaat tttttttatc agtccagcca gcttaaaaaa acattttaga
    64861 aaagtgaatg gaaaaagtgt tattagctat tttaaagaac taaaaatgga aaaagcaaaa
    64921 cgtctcgtgc tagaaaatga attaacctat acagaaattg cagatatatt aggatttcat
    64981 tcgatccatc atttttcttc agcttttaaa aaatatacag ggttatcccc ttcaaagtat
    65041 tatctatcct taaaatagaa aaaaattttt aggttttatc cacaaattat ttctctatat
    65101 tttctgtcta ttcaaaataa acaataattt tccggcacaa ttatttgctg ttttttacca
    65161 taacatagta cgatcaacgt agaaaaggag atgtttttat gaaagttgtt gtcattggcg
    65221 gtgtagctgg cggtccttca tttgccactc gtttccgtcg attgaatgaa gcgcacgaaa
    65281 tcattatcta tgaacgcgga gaaaatattt cttatgcaag ttgtgctttg ccttattatt
    65341 taggaggtgt gatcactgac cgtgactcgc tgatcgaacg tacaccagaa atattgaaaa
    65401 caaaaaacaa catcgatgtc tttactaaac acgaagtaac agcaatcgat ccttctacta
    65461 agcgattaac agttaaagac ctatccacaa atgaagaaat aaaaacagat tacgataagt
    65521 tgatcatctc ttctggtgct agaccagatt atccggatat tcccggagtt tttgaagcag
    65581 aaaacggctt tgtcctccgt agtgtgacgg atgcggatcg aatcaaatcg ttccttgaag
    65641 aaaaaaaacc acaacatgtc gtcattcttg gtgcaggtgt tatgggtctg gaattagctg
    65701 agaatttcaa gcatcgcggc ttagacgtga ctttaatcga tcaattgcca caagtcgctt
    65761 tcccttatga tccagaaatt gctaatttag tttatgacaa attgctgaaa gaaggattag
    65821 ccgttcattt agaaacaaga gttactgaga tccgtgataa aggtcgagaa atagtattat
    65881 cagatggctc cgtcctttct gctgatatgc taatttttgc tgttggtgtt tctccgaaga
    65941 atgaagtggt gaaagcaacc ggcatacaat tatcagatac aggtcagatc attgttgatg
    66001 accagttaca aaccaatctg ccggacatct atgcgattgg cgatattatc gaaacgacta
    66061 gtgtagtgac tggtcagccg atccaaagta tgctttccag tgcggccaat cgtcaaggac
    66121 atatgctggc agatatttta aatggtacgc ctatgcgcta tcgcggatat attggtgcag
    66181 gtgtcgcaaa aatctttgat catacagcaa gttatgcggg aatgacagaa catgaattaa
    66241 aagcatcagg cataacaaat tataaaactg tttttatcac tccctttgac catgcctatt
    66301 tctatccaga agctacaaga ttaaatctaa agctgatttt tgatgcagat agcggtcgta
    66361 ttttaggtgg acaagcattt ggagaaaaag gtgtcgataa acggatggga gaactttctg
    66421 tagcaatcac cggaaacttg acagtctttg atttgcctga tttggagttg ccttactctc
    66481 caccgtattc tactacccgt gacccgttga atatagctgg ttatgtcgca atcaatcaaa
    66541 tgacgaatat cgtagaaacg atcaaagcaa gtgatatacc cgaaaacgat ttgaaagaag
    66601 cgttcttttt agatatacgt gaacctaata aagcaccttc tggcagtatc tcggcaacaa
    66661 aaaatattcc aatgaatgag ttacgagatc gaatcaatga aatcccaaaa gataaaaaag
    66721 tttacattac tttcagaaga ggattgaata cttatacttc tgcccgaatc ttggcaggtt
    66781 tgggtatcaa agcgattttg attgaagaat aaaaaaacga ccgcggtggg tagccgcggt
    66841 ctaggagtta tttttacttg aggagtaaaa atgaaaaagt atatagggtt gttggttggt
    66901 atgtatatag aatagaagat aaatgtgaag aaattgtgca ttatttcttc acatttatta
    66961 ggttatagtt taagaaagtt taaacattgc gcaatttaat tattttagct gtttcttttc
    67021 ataaaaaaac atgttgtgac tctgagacaa atcatagtcc atagtgatgt ctctagagta
    67081 actacgccta atattacgag gcatcatatt aatctatcag cactagtacc taaactagca
    67141 tccctttcga atattttttc ttatataata aagtttgctt tcactcctct aatctcacca
    67201 aatcgactgg cttgcgttgt gtgatactag gaactgattg gtttagaacg acttttctat
    67261 tgtaatcata tttttcgcca tcctcgttgt cttctaatcc ttcaatgaat gatccctaat
    67321 gtgtgtatta aataatttaa tttttttgtt cctatttatt taa
//
LOCUS       DAIGUC010000008        61713 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.008, whole genome shotgun sequence.
ACCESSION   DAIGUC010000008 DAIGUC010000000
VERSION     DAIGUC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.008"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            598..1287
                     /locus_tag="NOB46_000519"
     CDS             598..1287
                     /locus_tag="NOB46_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1057492.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="NOB46_000520"
     CDS             1274..2482
                     /locus_tag="NOB46_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1057493.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="NOB46_000521"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="NOB46_000521"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCI1057494.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="NOB46_000522"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="NOB46_000522"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCI1057495.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="NOB46_000523"
     CDS             complement(6585..7280)
                     /locus_tag="NOB46_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HCI1057496.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="NOB46_000524"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="NOB46_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCI1057497.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="NOB46_000525"
     CDS             complement(8479..8670)
                     /locus_tag="NOB46_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCI1057498.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="NOB46_000526"
     CDS             complement(8691..9581)
                     /locus_tag="NOB46_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCI1057499.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="NOB46_000527"
     CDS             complement(9568..10335)
                     /locus_tag="NOB46_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1057500.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="NOB46_000528"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="NOB46_000528"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCI1057501.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="NOB46_000529"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="NOB46_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCI1057502.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="NOB46_000530"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="NOB46_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCI1057503.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="NOB46_000531"
     CDS             14906..15289
                     /locus_tag="NOB46_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057504.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="NOB46_000532"
     CDS             complement(15457..16215)
                     /locus_tag="NOB46_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HCI1057505.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="NOB46_000533"
     CDS             complement(16233..17051)
                     /locus_tag="NOB46_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI1057506.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="NOB46_000534"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="NOB46_000534"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCI1057507.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="NOB46_000535"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="NOB46_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCI1057508.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="NOB46_000536"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="NOB46_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCI1057509.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="NOB46_000537"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="NOB46_000537"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCI1057510.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="NOB46_000538"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="NOB46_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCI1057511.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="NOB46_000539"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="NOB46_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCI1057512.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="NOB46_000540"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="NOB46_000540"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCI1057513.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="NOB46_000541"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="NOB46_000541"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCI1057514.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="NOB46_000542"
     CDS             27093..27392
                     /locus_tag="NOB46_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCI1057515.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="NOB46_000543"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="NOB46_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI1057516.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="NOB46_000544"
     CDS             27980..28216
                     /locus_tag="NOB46_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCI1057517.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="NOB46_000545"
     CDS             28359..30332
                     /locus_tag="NOB46_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCI1057518.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="NOB46_000546"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="NOB46_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCI1057519.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="NOB46_000547"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="NOB46_000547"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCI1057520.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="NOB46_000548"
     CDS             33211..34503
                     /locus_tag="NOB46_000548"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCI1057521.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35239..36102
                     /locus_tag="NOB46_000549"
     CDS             35239..36102
                     /locus_tag="NOB46_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1057522.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36231..37853)
                     /locus_tag="NOB46_000550"
     CDS             complement(36231..37853)
                     /locus_tag="NOB46_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1057523.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38102..38623
                     /locus_tag="NOB46_000551"
     CDS             38102..38623
                     /locus_tag="NOB46_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI1057524.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38809..40538)
                     /gene="spxB"
                     /locus_tag="NOB46_000552"
                     /pseudo
     CDS             complement(38809..40538)
                     /gene="spxB"
                     /locus_tag="NOB46_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
     gene            40703..41521
                     /locus_tag="NOB46_000553"
     CDS             40703..41521
                     /locus_tag="NOB46_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCI1057525.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41624..41821)
                     /locus_tag="NOB46_000554"
     CDS             complement(41624..41821)
                     /locus_tag="NOB46_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057526.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41990..42568
                     /locus_tag="NOB46_000555"
     CDS             41990..42568
                     /locus_tag="NOB46_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI1057527.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42663..42800
                     /locus_tag="NOB46_000556"
     CDS             42663..42800
                     /locus_tag="NOB46_000556"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057528.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43613..44116)
                     /locus_tag="NOB46_000557"
     CDS             complement(43613..44116)
                     /locus_tag="NOB46_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI1057529.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44475..45500
                     /locus_tag="NOB46_000558"
     CDS             44475..45500
                     /locus_tag="NOB46_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI1057530.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45847..46725
                     /locus_tag="NOB46_000559"
     CDS             45847..46725
                     /locus_tag="NOB46_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HCI1057531.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47201..47317
                     /locus_tag="NOB46_000560"
     CDS             47201..47317
                     /locus_tag="NOB46_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI1057532.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48245..48583
                     /locus_tag="NOB46_000561"
     CDS             48245..48583
                     /locus_tag="NOB46_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057533.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48677..48907
                     /locus_tag="NOB46_000562"
     CDS             48677..48907
                     /locus_tag="NOB46_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057534.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49307..49678
                     /locus_tag="NOB46_000563"
     CDS             49307..49678
                     /locus_tag="NOB46_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCI1057535.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49952..50644)
                     /locus_tag="NOB46_000564"
     CDS             complement(49952..50644)
                     /locus_tag="NOB46_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1057536.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50647..51432)
                     /locus_tag="NOB46_000565"
     CDS             complement(50647..51432)
                     /locus_tag="NOB46_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1057537.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51669..53069
                     /gene="lacG"
                     /locus_tag="NOB46_000566"
     CDS             51669..53069
                     /gene="lacG"
                     /locus_tag="NOB46_000566"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI1057538.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53094..53411
                     /locus_tag="NOB46_000567"
     CDS             53094..53411
                     /locus_tag="NOB46_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI1057539.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53424..55097
                     /locus_tag="NOB46_000568"
     CDS             53424..55097
                     /locus_tag="NOB46_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCI1057540.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55111..56742
                     /locus_tag="NOB46_000569"
     CDS             55111..56742
                     /locus_tag="NOB46_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HCI1057541.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57603..58793
                     /locus_tag="NOB46_000570"
     CDS             57603..58793
                     /locus_tag="NOB46_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HCI1057542.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58927..61116
                     /locus_tag="NOB46_000571"
     CDS             58927..61116
                     /locus_tag="NOB46_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1057543.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61113..>61713
                     /locus_tag="NOB46_000572"
     CDS             61113..>61713
                     /locus_tag="NOB46_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI1057544.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNI"
BASE COUNT        19198 a        11237 c        12196 g        19082 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgagca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaacaaacgg tgttcaaaag cttgcatcta cggcactaag
    34681 cccaatcaga tgaaaaatat ggagtgctat ttttatctga ttgttcttac tgcttgatgc
    34741 agagcagctt tttcacaacc tctccactaa acggtgttct cctgccaact cctcggtcac
    34801 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg
    34861 agctaaacgg caggctcaca acctcttggt aaacggtgtt caatcagctg accctcggta
    34921 ttagctcaaa aaacggcaaa atatgaggaa ctattttttc cgtttttttc tctaatactc
    34981 aggtcaaaac gctgatttca caacctctga ttcacggtgt tccagaagta gcttctacgg
    35041 aaataagccg aaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc
    35101 ttgaagctga ccacttctgt cacaacctat tattttgatt agaacttgcg aaaataaacc
    35161 ggttaaagtg tgtctagcgc aagagatttg ctataataga cgataagggt aaaatgtaac
    35221 gagaaggggt tgaaaaatgt gtatcaaatt gtaacagatt cttgttgtga tctgccatac
    35281 catgtattag caaaagaaaa agttgatttt ttatcaatga atctccaatt gaatgatcaa
    35341 gagttagtag atgacctcgg aaagacattc aattatgacc gctacatgaa tcagctgaaa
    35401 aatggtgcga tgcctacgac atcacaaatc aatgttggcc gatatttaga atttttccgt
    35461 tcttatgcgg aaaaacagat tcctgtttta tatgtggctt tttccagtgg attaagcggc
    35521 tcttacagta gtgcgcttca agcggttgaa ttgctgaagg aagaatatga agaccctgag
    35581 atctatgttt ttgatacaaa agctgcaagt attggggaag ggcttttagt attggaagct
    35641 gtaagattga aaaaagaagg taaaagcatc gaagaaaccc tagagtggct ggaaagtaat
    35701 tatttgaaag tccattcatg ggtaacagta gacgatctga aatatctaga acgaggcggt
    35761 aggatttcca aagcaagtgc tactcttggc agtctattga gtgtaaagcc tattattacg
    35821 gtggataaag aaggaaggct gacgaatgtt gacaaagttc gaggaagaaa caagtcgatc
    35881 cagacaatcg tcaatgagac ggtaaaaaca atcgttgcac cacttgatca aatcgtttat
    35941 gtggcttacg ctggggatct agagagcgcg gagaaggcaa aacggctttt ggaagagcag
    36001 ataaagatga aagatgtgaa gctttatccc ttaggaccaa cgatcgccag tcacacaggc
    36061 tatggctgta tcgcgatttt ttcgatggga atcagtcgat aaaagcagta actcattctg
    36121 taaaaaagcc cagaaattga ttgtaacaaa aacagcgact cttaaaagat agatgagcat
    36181 cctatctctt agaggtcgct gtttttttat tttttaagct aaataggcca ttatgcccat
    36241 aactcgttca attgtttttg aatatctgca ttttccaaaa attcatcata tgtcgtatca
    36301 gctcgatcga tcacaccttt atccgaaacg gcaatgatgc ggtttgccaa tgtttggata
    36361 aattgatggt catgtgacgc aaataagatt gagccagtaa atgccatcaa gccgtcattc
    36421 aatgctgtga ttgattctaa gtctaaatgg ttcgttggat catctaatac aagtacgtta
    36481 gctttcgaaa gcatcatttt tgaaagcatg caacggactt tctctccacc agataaaaca
    36541 ttcactggtt tcaatacttc ttcaccagaa aacaacattc ttcctaagaa gcttcttaag
    36601 aaggtgttat catcttcttc tttacttgca tattgacgca accagtctaa aatcgttaga
    36661 tcagtatcga attctttcgt tgtatccttt ggtaaataag aattacttgt tgtcacaccc
    36721 caacgtactg ttccagtatc tggcgtaatt tcacccatga taactttgaa tagcgttgtt
    36781 gttgttatat cattttctgc gacgaaagcg accttgtctt ctttgctcaa attaaaagat
    36841 atatcatcta aaattttctt tccatcaatc gttacactta cattttctac ctgcaataag
    36901 tcgtttccaa tctcacgttc aggtttgaat ccaacgaatg gataacgtct agaagaaggt
    36961 tggatatcgt ctaaagtaat tttttcaagc atttttttac gtgaagttgc ttgttttgat
    37021 tttgatgcat tcgcactaaa gcgggcaata aattcttgga gttctttgat ttgttcttct
    37081 tttttggcat ttgcgtttgc ttgaagttta gccgctagtt gactagattc caaccaaaaa
    37141 tcataatttc ctacataaag tttgatttta ccaaaatcta gatccgccat atgtgtacat
    37201 actttgttca aaaagtgacg gtcatgggat acaacgatca cagtattttc aaaattgatc
    37261 aaaaattctt ccagccaatt gatcgattgg atatccagac cgtttgttgg ttcgtctagc
    37321 aaaagaacat caggtttacc aaatagtgtt tgtgctaata acacttttac cttttgtcca
    37381 ccagttaatt cactcatttg ctgatggtgc aattcttcag ggatgttcag accttgcagt
    37441 aaaacagctg cttctggttc agcttcccat ccattaagct cagcaaattc tccttctaat
    37501 tcagctgctc gaataccatc ttcgtcagtg aaatcctctt tcatgtaaat cgcatctttt
    37561 tctttcagca cttcatacag acgcttgtgt cccatgatga ctgtttcaag tacagtatag
    37621 tcttcatagt cgtaatggtt ctgtttcaat acggccatcc gttcatctgg tcccatagta
    37681 acggaacctg tggaaggctg cagatcccct gataacactt taaggaacgt tgatttacct
    37741 gcaccatttg caccaatcaa gccatagcag tttccggggg taaatttaat attcacatca
    37801 tcaaatagtt tgcggtctga aaagtgcaaa ctcacatcat ttacagtaat caattttttt
    37861 cctcactttt atcattatta gttttgacaa gtcttataga attatatagg ggaaaggtaa
    37921 aagattcaag gcaatcgaac attctttgtg tttcacgtga aacagaatga aaaaaataaa
    37981 aataaaagcg gagcgaaaat agctactata ggatttatta gtttgcaaca gcataatttt
    38041 tgacgttatt tataagaggg agtactataa aactgtaaaa gaaatgaaag aaggattgaa
    38101 aatggatgaa aaaagaacca tcgactgggg ctcattgatt ttgggaattt tatttgtact
    38161 tgtctcattg ttatcatttc aagaccctgt cggaaattta gttgcaattg tagtagtctt
    38221 tgcgattttt gcctttatta aagggatatt tgaactgttt gtacggaaca gattaaaaga
    38281 gctaacagga tataaaggaa agatgccctt aataatcggg atcatcgata ttctagttgg
    38341 cgtctttttc ttattcaata ttggtgcagg agtcgcagca ttgccttttg tttttgcagt
    38401 atggtttatt gctgattcag ttttagcgtt atttactgct gacttggcaa gaggagtaag
    38461 tgaaggatat tattggttta cgatcatcgt caatatttta ggaattttat taggaatttt
    38521 cttattgttt aatccaattt cttctgcgtt gacattaagc tttttagttg gattctattt
    38581 tatgttattt ggtatcacac atatcgtcta tgcatttaga taagtaaaat caaacaaata
    38641 aaaaagccgg cttccgatta cagttttact gttgtaattg gaagccggct tttttatcat
    38701 ggacaaatat gcacgaggtg atttttaggt gtcgagacaa atttatgcaa aaatgtgaga
    38761 agctatatac acaaatttta tcttaatact cgaagcatag cgcagttgtc acaacctctt
    38821 ttcatataat tcattcaata ctggcaaatc atggacttca tatttttctt tgaatgcttg
    38881 gatttcttct tcagaatatt ttcttggatc taaatgcaga tcttctactg gcaatgggtg
    38941 cttgttattg atcttcacat cgattactac aggacgatct gattttgcag ctgcatcaaa
    39001 ggcaaatcga agttgcgagt attctgtgac tgtaaagcta tttgccccga gcgcttctcc
    39061 aactttaccg aaatctgcat cttctaaaaa tacaccaaat ttcttttgtt ccgtatcttc
    39121 ttgttctgct tcgatgaaac caaaagaatc attcgaaaag acaacattaa taattggaag
    39181 ctgatatttg acttgtgtaa tgatatcttg catgaccata gcaaacccgc catcaccact
    39241 taaggtaaat acttgttttt ctgggtagct tagttgtgcg gcaattcctc ctggcacacc
    39301 attacccata gttgcgaacc atccagatgt cgtatgtttt tgtttaccgt tcatattcaa
    39361 taaacgaata gaatggatag tcgtgttacc gacatctgtg acgaaaatcg catcgtcttc
    39421 agcaatacga ttgatttctt tatagacagc ctctggacga atcggttctt cctctcgatc
    39481 ttcaaaagat ttcaaccaat ttacccattt ttctttattt tcttgatttg ctaggtacca
    39541 gctatcagca gggcgagcat cccctaactc gacaagtctt tgcaaagctg tgtttgcatc
    39601 accgaggatc gacaaagatg tttcatggcg tcgtccaaat tttgacgcat cgatatcgat
    39661 ttggataaat tcagcagttg gattaaaaaa tgcacgtcca aatgggaagt cgctaccgac
    39721 aaataagatc agatcggctt ctgccaatgc ttcatttccg ggtttagtag cgacacgtcc
    39781 agcaaaacca agaaagtttt cataatcatc aggaataatt ccttttgcta gaacggaagc
    39841 gacaacagga actgaaaaat gttctgagaa ttctttgatt tgcggaaatc cgtttcgcgt
    39901 tccttgacca acataaagaa ctggtttttt tgctttttca agataaggca aagcagctag
    39961 caaatctttt tcttctggta atatcacact tgttttgtga gtgtgagcgg tggagaaagg
    40021 ttgttcgtca atttcttcaa aaccaagatc aacagggata gtcacgatag ccacgccttt
    40081 atgctcatag gcggctttaa tggcttcatc tactacatgc ggaagacttt gtggtgtcat
    40141 gactgtacga ttgtatacgc taacatctgc gaaaatagga ttttcattag ttcctggaaa
    40201 gagttatagt tcatggatgt agaagcaact tgtcctaaga acgctactag aggcacatgg
    40261 tccatctgtg catcatacaa accattgatc aaatgtgtcg caccaggtcc tgcagagccg
    40321 aagacagcgc cgactttccc cgttaatttt gcatctgcag cggctgcgag tgcgccgact
    40381 tcttcatgac gaacttgaat gtagttgatt tcggtttttt cttgatatag cgcatccata
    40441 attgaattga aagatcctcc gggaatgccg taaatatggt cgatacccca gctttcaaga
    40501 acttttacca ttgcgattcc tgcattgatt tttgacatgg tgtttcactc ctttagcaat
    40561 gatgatacat aaattttttg tatctagagt atagaacttt ttatcgaaaa tcccaactaa
    40621 ttcgtctttt cacaaaaatg tagtcatgtt tttgggaata tgctagagta gtacatagat
    40681 agattcaaga gaggggaatg gcatggttga atggctattg agacttgaac cttggcagca
    40741 agcacttgct gggacagctt ttacttattt tatgacagct cttggtgccg ggttggtttt
    40801 tttctttaaa gaaatcaaaa aagaagtgct aaacttgatg ttaggatttg cttctggtgt
    40861 catgattgct gcaagttttt ggtctttgtt agatccggct attacaaaag cagaagaaaa
    40921 tggagatatt gcttggctag ttgtaagtat tgggtttggt ttaggcggtg tgtttttata
    40981 tatggcagat aaaacactgc cccatatgca ttttggacca caacatgaag cagaaggatt
    41041 gcctacccat ttaaaacgga cgatcttgct tgttttttct attacattgc ataacattcc
    41101 tgaaggttta gccgtggggg tagcattcgg tgcagcagca actgcggata atccgacagc
    41161 cgctatatta gccgctgttt cggtggcgct aggtattggt atccaaaact tcccagaagg
    41221 agcagctgta tcaatcccgt tgcgacaaga aggtctgagt cgtaaaaagg cctttgttta
    41281 cggacaagct tctggaatcg ttgaaccaat tgctggagtg attggagcgc tactagtaac
    41341 gaaagtggag ctgctgcttc cttatgcact tgcttttgcc gcaggagcaa tgatttatgt
    41401 cgtggtggaa gaattgatcc ctgaagcaca gcagacattg tccagcaaac gtcattttgc
    41461 agtttttggc gtcatgagtg gatttatcat tatgatgatt ttggatgtgg cattaggata
    41521 aataaaaaaa atatatatga tatatcaaat agggccgcga acttatatcg cgaccctatt
    41581 tttttagtaa gttatatcat aatgaagtga atggtatcat acattaataa tagttttttc
    41641 tatgtgtatt tcctttgatc cagcgaacaa gccagatgat aagtgcgatt gggattagaa
    41701 ctttgaccgc aaaccataaa agcccgctta ggacactgac aaaaagactg atgacgaagc
    41761 tagctgcaat tagcactaaa agaaccatga agatatttaa gaacatattt ttttgacgca
    41821 tacaaaaccc tcctcttgtt cattctttac tatagaaaaa gtataacagg gattgtttaa
    41881 aaacacctcc aactgaagac tgatttttac ttcatctact taaatgatca aacaattgct
    41941 ttttctctgg tttatcatct aaaatagagc ggaaaaggag gagaatatca tgcctaaaaa
    42001 tcgtcttgaa gcatttacag atgctgtaat cgcgattatc atgactattt tagttttaga
    42061 acttcatgaa cctaacggag acacgtggga ggcgctcgct gcattaggtt accgattttt
    42121 tatctatatt gtcagtttta tcattttagc gatttattgg aacaatcatc atcatttatt
    42181 tcaagttgta cataagataa atggacgggt cttatgggcg aacagtttct ttgtttttgc
    42241 gctttcgctt tttccgtttg caacttcatg gatcagtgag tacatcaata gcctggctcc
    42301 agaaatgact tatggttttg ttaccttgac cgctaatatt gcgtattata tcttggcaaa
    42361 agaacttgtc aaagcaaata aaggccacga gaaagcattg aaggcgatgt tgaataatta
    42421 caagaaatcg tatctatcga ttggtttgaa tgtgttagga attgtcttag ggtatttagt
    42481 agcgccagta gccgtgctga tcgcaaacat cgtgattcta gctgcttgga tcatcccaag
    42541 tcgtaccatc gaatcacaat atcggtaaaa tgatccgtgt ttaaaattta agagaaaaat
    42601 atagaaaaaa taaataaacg atcaaatatc cgagtgatac tagtattcaa agagggatgc
    42661 agatggatca aaaaagaatt catgtaggac tgattactag ttttgtcacg atgcttattt
    42721 atttggatca aggtcatttg acttggacag tagttggtgt cgtaggattt ttgacattat
    42781 tcacagcaat aaaaaaataa acatctttat gtaatctgat gttctatcta tttaagaaaa
    42841 gcatgtttac agcagtatga ttctgttgta aacgtgtttt tatttgtgga aaatttaatt
    42901 tttagaaaag tgtatcgaaa aatagatagt tagtttttcc acagtggata acttcgtaag
    42961 agataaaaat aaaaaattag tcaaagaagg gcgtatagat ttcttttgat aggagatata
    43021 caacagaaat gaataaatat taacgtgttt tcaaacagta taaaacggtg tggtttttgg
    43081 aataaaaaaa taacatatct cattttacgc ttttgttatt ttatacttaa aaaataacga
    43141 cacagaaaat accgtgtctc agatttctct actacttcta aaaactactg tttttttcct
    43201 ttgaaatgcc ttcaaaaagt aggatcaggc agaatatact ggcagaatca aggagaaggg
    43261 agcctaaata aggagaaaaa ccatagaaaa tataaagtaa ttacttataa aacaagcttt
    43321 ttatagaaaa ataatatacc tgagtagggt ataaattaag acggaattcc tttctagatt
    43381 gagatattga ctaggaagaa tgttaagatt ttaagccttt aagctaaaaa aaaacccttt
    43441 ttgttaaata aggggaatat agcctgtcag tttcaaactg caagtcgtcc tgctgcaata
    43501 atatagtaga ttagagatga aaatagattt ttttaaacca atgactgaat aaaaagaccg
    43561 tcatagatac acattggaat gtgtctatta cggtcttttt ttacgaacga ttttattgaa
    43621 gacggacagt tcgggtcaaa aataaaaaag ctacgatcag aaataagaat aaaatgtatc
    43681 ccaaaataat ggctagacgg tctaacttat ttgtcgatag atgtttgttt agaagttgat
    43741 aggcccataa acctatcagt cctcctgttg tattagttat caaatcagtg atgtccgcta
    43801 cgccaatacc gaataggaat tgaatcaatt ctgccaagaa gcttacaagg aaaataatcc
    43861 ctaatttttt agaaaaagaa agtctcttga aattgacatt caaaagcacc ccaaaaggaa
    43921 aaaagacaat caagttataa gtggtctcac gtaataccgt cgtattttca aaagaaaaag
    43981 tagaaaaagg gacgagattg acattgctgt aagaataagt gagaaattgt ggaagattaa
    44041 atgatagctt gaataaaatc aaccataata gaaagaataa ataaatccct aataaaaatt
    44101 ttgatacata ccgcatagac atctcctcca tttaaaaagt ataccatcga aaaccgctga
    44161 aaaatcataa aaaagtatga agtttaagga ccaacgtagt tatcgtacga aaattagaag
    44221 cttttttttg ttgggaatcc ggtttcttta acaaagctaa gatagcgagt tgcttggaaa
    44281 agttgctatc ttttttctgt caaaacgact cggaatgttc gttttttgtt ctaatttctc
    44341 caagttgttt actttttgat actaagttta tgaaaaatca agaaatagtt gttatactag
    44401 gtaatgctga caaacgggat tggcatttca tcttggttca gctttttttc caattactag
    44461 gaaggaggga tagattgttc aagacttatt ttcgtttcaa taaaatacaa gataatcctt
    44521 ttcgtatcat gaatctgatg ctacttatct ttattgtatt atggttaggt tacataaatc
    44581 atgatttttt gatttcaagt ttttcatcat tagggatctt tacttttttc tattatcaaa
    44641 acataccgat gaaatatttg ctgaaacgta tgtttctgat cggttgcgga ctgttggttg
    44701 ctttcgtttt ggggatctta tcgacttatg ttttatggct tgaaccattt gccgtagctt
    44761 tggttgcttt ttccagcaga ttcgtgttgc gattattcca tatttctaaa ccaggtggct
    44821 tgttttttgc gatgctttct gccatgggaa cgagcatgca gctgccaatc gctcaattac
    44881 cgatcgtctc actttatttt tttatgggtg tcgtttttgc cctgattgcg gcagtgatta
    44941 caaaattact ggattcacgg cctgagcaga caattgaaaa agcaacttta aaagaaagat
    45001 ttcacgaaga gcctttagtg atcattgatt ctgttttcta cagcgctgcc ttatttcttt
    45061 ccgtttatgt cagtcacggc ttgaatctgc ataatcctta ttggttgacc ttgtcatgtg
    45121 catcgatttt gctagcagaa aacttggatg cgatgaagca tcgacaagtc caatatctga
    45181 ttggatcgat gggtgggtta tgtgtgtcgg cattcttgtc atttgtgccg tttacgcagt
    45241 tgcagaccat ttttctgatc acttttctat atggaatcgc acaatttcta gttgctagaa
    45301 attatgcagt tgctaatatt tttcttaatc cgatggcgtt gatgctatct acacttattc
    45361 gtggagcata cttgatttct ttgatcgaat atcgtttttt agggatcgtc ataggaagtt
    45421 tcatcggttt aggtgttgcg tgggtaatga cggttggttt gcaacattat ttaacggttg
    45481 ttcgtcaaaa attagaatag aaggacaaat atatgtgcca aaagaggtta tgacaagatt
    45541 tttgtcacaa cctctaattc aaggtgttca aaagccagat tctcagcatt aagtcaaatt
    45601 cacacaaaaa tgtggaaagg aactttcaaa aaaattttat atttattcta tcaaaaaatt
    45661 ttatatttat tctatcaaaa aattttgttt atgatggtaa ctgaataaac tttcctgaga
    45721 tggtcaatgc tttccttgaa agtcttacag atattctttc ttcatagaaa gtttaagttt
    45781 tatagttagt gtacaataaa agtatgttta taccatatgg tgtccggata atcagtcatt
    45841 taaacaatga ggttcaaaga tatgaaaagg ggaaatttga tgaagaaaat aagcaatgaa
    45901 atccaaattc tggcagaaac tttaactctt cccaaagtcg ttatagagca aatgattgta
    45961 caagcaaaaa acatccttga tgaggtgttt gagcaatata gtcatgaact aatggatcct
    46021 aataaagcaa aggcgactgc aaagaaaata gacaaagtct atgaagagga accttttgca
    46081 gcattagcta tttatctata tgcagcttct caaagttgga aaaaaattta tcaaccattg
    46141 aagattccaa gaactatcta tttggcaaca atgaatgctt ttactagatt tattcatgaa
    46201 catttccaag taacaggaag ctatcgcttt gaccgtggtt tttggatttg gcattacact
    46261 agtggcttga tctttcggat tggtgaattg gagtacgaaa tgacatattt tccgaaaggg
    46321 tacacggatc taagattaga aggaaagcag tgcctttctc ttcatattcc ttccgatgca
    46381 gatttatctc agaataagat aagagatagt tacgaaagtg ccattcgttt ttttgaactt
    46441 tattttcctg attaccatta ccaagtgatg tacacagata cttggttact atcacccaat
    46501 cttactaaat ggttgaaaaa agagtcaaaa atctgtcttt ttgcagccga ttatcgatta
    46561 ttatcagttg atgaacagga cgatagtgga gtcccttgga tctttggacg agtagatgcc
    46621 caaatacatg attatccaga aagtacgagt ttacagcgac aagcaaaaga gcaattgctt
    46681 gcaggcgagc acattggctc tggcttaggt attcttactt cataagttta gtacttcgaa
    46741 atagtttaaa agagcgtgag acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
    46801 tataaacggc ggaagcagaa gcaactcctt cggaaataag ctgaaattca caaaaatttg
    46861 aaaagcaatt ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
    46921 cttttttagt gttctatcga acacacagta cgttcaatag gtaaactagc tataacaata
    46981 gatattaaag ttaacggaca agagggcctt ttttaggtag ctaaaacgta ataatgaaaa
    47041 tttatttcca gagataggag tcaatcagct agtctgatcg actgttttaa caagttgact
    47101 ttcattttaa cttttgatac catttaaaac acaaatcgta attgtttcga tttgtgtttt
    47161 ttagcatgac tacaatcaaa gaagaaagtg ggtcgtccat atggaaaaaa cagatatctc
    47221 aagtgcatac cgccgcttga aaagcccaaa tatcaaaaca cgaaaacgtg cgctgaagat
    47281 catcaaagat gtgaaacgga atagtgggaa aaggtaagaa gaaggaaact taattaaaaa
    47341 aatagccgaa aaacgttttt cggctatttt caataatcgg tttttgtgta aggtttccga
    47401 aagaactgct gttgattttc catttttaac atatgataaa ttggtagaat ctttcttttc
    47461 aaattgatac cattccctaa ttccagttat atagttaact acagaaccac aaagcacgta
    47521 cgtttataaa agtattatct gtagttattt ttcaattccc tttcaacctc ttattttgac
    47581 cagtagtatt gatcacttta ccttttaaca cctttgttcg tttttgaaac atttttagtc
    47641 aagaatggaa acgtaactac ataatcaaag gttttgcgaa atatttcatg aaatatttca
    47701 tgtagaagcg agcaatacgg ttgcaaataa ccattatcgt ttaataagca gttacgaaag
    47761 ctcccaatat ctctaacgtt cagctcactc catttctttt cttcaaaaaa atcagtgatt
    47821 cgtatctctt tctatttgtc gaaaaagtta actttaaaaa gtaacgccga aaaaatatgc
    47881 aaaaaaataa aaaagcagtt actattgcta gaataacatc aaggaataat aagttttggt
    47941 tttcagataa tagtcgataa gttgtgtatt ggaattttag atacagtaat aaagtatttt
    48001 tcatgaaatt ttgtgagaat cactattaca agtatcttta ataaaattaa tggttaagga
    48061 ggaacttaaa gtagaatgta aatgaatagt tgtagtcagt cgattgtgat actagactca
    48121 aagttgcagg aataagtttt tcaatttgtg attggaagat aaaaaatgaa aaagaagggc
    48181 ttttttttat actttgttga ttgtagtgtt tattttccct ctgtttagcc aagtaacatt
    48241 ttctatgact caaccagttt caagtgagga acatgataac ctttttcgtg ctacagaaga
    48301 gtttaagaaa tatcaggaaa atattgttcc ggagactcca ttagctagtg agccaattac
    48361 tgatattgat ggaaaccaaa taggatggta tatacagtac gaagttatgg tggtaaataa
    48421 tgactcaata gtaaaaaata cagtaggctt agagctaaca ccgattgaaa aggtgagttc
    48481 attgttaacg tatatttata ctgatgaaag tgacgagact gagatcattt taacggatta
    48541 ctcaaaaatt gctactgata aaaagtatat attgtggatg tagacactag tgaaatactt
    48601 tatgatatag aaattgatga aaatttacta gatgtagcac aagaaatcga tcatcaaaag
    48661 caggaagcta ttcgatatgc tggtagaaaa gggaaaagaa aatatttatt acgtgaatgt
    48721 agcaaaagtt agagaagatg aaaatgagtg gaaagaattc aagagtcgct actcaattaa
    48781 ctcgactccg acatttacag tttacagaga aggatcgata gaaaaaactg ttttttggac
    48841 taaagaaagt ggaatgtctt tagctgaagt agaagagttt ttggattatg ttagtatgca
    48901 acagtaaggg agttcttatt atgaaaaatt ttgacacata ttatgttatt gttttttcga
    48961 tatctttgct gttaatatta ctaactttaa tgcagtataa agagtatcca gagtatttta
    49021 ttttaacttt tgtatattta gtaagtagct acacacttct atataaattc agaagttctt
    49081 ctagagtttc taaagtttgt ttcttaatta gcttattgat tctataatat ttttgattta
    49141 tataggaaat taaaaatatt atagaatcaa cactcagaga acgggttggt ttttaataga
    49201 tttaataagt actgataatg aaatttctcc tggttgggaa aacgaagttg gttaccctgt
    49261 agaagaattt tttcaagatt actttgcgga gtatgccgat aggataatga gagattacgt
    49321 aacagataaa actcaagaag tcatcaatca atcccagtca ttaaatgaat tatctgataa
    49381 ggcgaaagaa gaagcagttg ccattatttc ttcagggatt agtgactata ttgatatgag
    49441 tggtgaaatc aattatggcg ataaagacaa aattgtacgc atgataaaag cttttatcaa
    49501 aacttttgat gtgaaggcag atcttaagtt taatgatact tacctagtag gaaaattaat
    49561 taatatcctt gggacagaga aagatacgga aacgtttatt tcctctttgt ctatgttgtt
    49621 tacagataag catttttcaa ctcagcttgg tggagaggaa ctagtggaaa tcttttaacc
    49681 attacgccca gcattaataa aagtatatca aaaaagtact cctgatgatt tttaagattg
    49741 gtttgagaaa taatgtgaaa acactatttt taatgttaat tatagataga gatgaacgcg
    49801 tcatatggtt aaaagaatga aaaagtcaaa gatacactgc tatatttcac taaggatata
    49861 gcagtgtatc tttcatgtcg tttcactggc agttttttat aaaaggaggt gtgcatttca
    49921 gttgcttttc tttggtagtt agttgaatcg tttaagaatt aacggatgtg gcagacaggt
    49981 gctctgtcca aaaaccagta aaatctttga tggttccatc tttatttagc tgtgcctgtt
    50041 caaatactgt tttgttttta ccgaatggat caattgcaat aattgttccg atccccgcac
    50101 gtttggcagc aagtaatcct gagtaagcat cttcgataac aagacaatca gccggagcta
    50161 agctcagttt gtctgccgct ttaagaaaaa tatccggttg cggtttccca gggaaagagc
    50221 cgtcgtcata gacaatcttg tcccagtcaa accagcgggc taaatcgaaa atatcaaaat
    50281 aaaaagcaac attctctttg acagtagccg tggcaatcgt taatggaatc tgttggtcag
    50341 tcagctggtc aagagtcgct tcaagccctt ttgtcaactg aagctcgttt tcattttgca
    50401 agcaaagcat acgataatag ctttcttttt cttctgacaa tacggcgatc tcagaggcgg
    50461 tcaaatgctc tgaaatgaaa tgtttcaaaa tctccgtatt cgtccgacca tgaatatttt
    50521 ttaaaatatc ctcgtctgat aaaccatctt ttgtatgatc atgtatcata tgcagccaag
    50581 cagcttcatg cagatgagag tccaaaaaca ttgttccgtt gaaatcaaat ataatccctt
    50641 tcatagttac gctcctatag tggtattttc ggttgaatca gcaatttgca gatcgacata
    50701 ttgtgcatag tgctcttgaa cctcccgcga gatctggcga tccgtaatga gcagatcgaa
    50761 atcatgcaaa ttataaaaca cataaaaatc atctcgattg aattttttat tatcaacgag
    50821 tagatatttc ttacgggaat tatttagagc gatctgctgt gcttctcctt cttcggtact
    50881 gtaagtagag atcgcttcgt tgtgaacgcc atttgaactg ataaatgctt ttgtaaactt
    50941 tagtcttctt aaattgtcgt tggtgatcgg tccgacaaat gcgccggtat ttttccggaa
    51001 atcaccgcca atcagtagaa tttctggtcc atctgcttga gcaagaatat caaaaactgg
    51061 ataattattt gtaatgatcc gaattttctt gttcagtaaa tgcgtcgcca atagttcgat
    51121 tgttgtacct ggtcctaaga aaatcgtttc tccctcgtga atcaaggagg ctgctgtggc
    51181 agcaatttct tttttttctt gaatctgcag agtggctttt tcagtgtgag aaagttcttg
    51241 atctaaagtg taggaaagac tttgagcccc tccatggaca cgcagcagct tgcccgattt
    51301 ttctaattca tctaaatctc tgcgaacggt catatcagaa acatctaatt gattgatgat
    51361 ttcattaacg gtaaggattc cttttttatt gaccatttct acgatagtaa gcaatctttc
    51421 ttttttcaac attgtcttca cctctaattt aaggataatc tatcatataa acggacaaca
    51481 gtcaatctaa ttcgaacaaa agtaaacatt tagggtggtt tttatgtttg ttacaataga
    51541 ttttattgct gttttctggt ttttatgatt atttgtgttt gtttttgttg acaaatgttt
    51601 tggatgcgtt tacaatgcaa tcagttagaa agagcgaaaa ctgattatag atttgaggag
    51661 agatgtacat gcttaaatta ccagaagatt ttatttttgg cggagccaca gcagcctatc
    51721 aggttgaagg agccactaag gaaggtggca aaggcgctgt tgcttgggat gactttttag
    51781 aggaacaagg gcgattcagt cccgatccgg caagtgattt ttatcatcaa tatgcaaagg
    51841 acattgaatt gtgtgaacgt tttggtgtaa atggtctaag attatccatt gcttggagcc
    51901 gcatttttcc tgatggagct gggaaaccaa atccagaagg aatcgctttt tatcatcgtg
    51961 tgttcgaaga atgtaagaaa agaaacgtaa cgccgtttgt gacgttgcat cattttgata
    52021 cccctaaacg tttgtttgac catggagatt ttttgaatcg agaaacaata gaagcatttg
    52081 tttcctatgc cattttttgt tttcatgaat tcaaagaagt caaggtgtgg agtaccttta
    52141 atgaaatcta tccagttgca accaatcaat atttgttagg tgttttccca ccaggaatca
    52201 aatatgattt tacaaagatc gtcgcctgtc ttcataatat gatggttgct catgcccgtg
    52261 tagtgaacta tttcaaagaa aacgaacttc cgggtgaaat tggtgtagtt cactcattag
    52321 agacgaaata tgcggcaaca gacgcgccgg aagataagca tgctgccttt ttagacgatg
    52381 cattgtcgat ccgtttctta ttagatgcta cctatttagg ctattattca actgaaacct
    52441 tgactgctct tgatgagata tgtgaagcaa atcaggccag ctatcatttt cctgaagaag
    52501 atttcgttga attgaaaaaa gcatccacgc gtaatgacta cttagggatc aatcactacc
    52561 aatgccattt tgtcaaagct tacgatggag aaaatgcaat ccatcataac ggtacgggtg
    52621 aaaaagggac ctctgtttat aaagtgaagg gaatcggaga acgtatttat aaagaaggaa
    52681 ttcctcgaac tgattgggac tggctgattt atccagaagg tctatatgac ttgttgctgc
    52741 gaattaaaag cgattaccca cattacaaca aaatctatat cactgagaac gggatggggt
    52801 ataaagatca gtttgaagat ggcattatta tggatcagcc gagaatcgac tatttgagag
    52861 tctatttgga atccttaagc aaggcgataa cagccggggt aaatgtgaag gggtattttt
    52921 tgtggtcgct tatggatctt ttctcatgga caaatgggta taacaaaagg tatggcttgt
    52981 tttatgttga ttttgaaacc cagaagcgtt acccaaaaga atcagcttac tggtacaagt
    53041 tggtcagtga aaccaaaacg attatttaat aagtgataat ggaggaagaa aagatgaata
    53101 aagaggaatt acaaatgctt ggttttgaga tcgttgcata ttcaggcgac gctcgcagta
    53161 cattattgaa attattgaaa gaagtaagac aaggaaactt tgaacatgtt gattcggcgt
    53221 tgaaagaagc cgacgaaaat ttaacccttg cacataattc gcaaacaaaa attttagcgg
    53281 aagaagcatc tgggaaagag atggagatgg gattcatttt tatccatggg caggatcatt
    53341 taatgaccac tttattgctg agagatctga ttcaagactt tattgtactg tacagacaga
    53401 atcaaggata ggagaagaac gctatggatg gaatcattaa acaaatcgaa aaagggaaac
    53461 cattttttga aaaaatctca cgtaatagtt atttaggagc cgttcgtgac ggatttttaa
    53521 cagcgatgcc agctatttta ttttcaagca ttttcatttt gattgctgcg gttcctgaga
    53581 tttttggtta ccaatggcct gaatctgtct ccacatggct atggaaagtc tataattatt
    53641 cgatgggtgt tgtagggtta ctcgtttcag caaccactgc tcgctgcttg gctgattcga
    53701 tgaatcgtcg cttaccgaaa aacaaagtaa tcaacaccac ctctgtgatg ctggcctctg
    53761 tggtaagttt cctgttgtta agcgtctctc cgattgaagg tggattttca acggaatata
    53821 tggggacaaa gggactactg gcttcctttg tcgctgcatt tttaacagtt aatttatata
    53881 agttttgtgt gctgaaagat attaccatta aaatgcctaa agaagttcct ggaacgattt
    53941 cgcaaacctt ccgagatatt tttcctttct ctttttcagt atttgcggcc gttttaattg
    54001 atttaggcat tcgacaaatc ttccaaatct catttgcaga agcaatcatt acggtgctgc
    54061 agccgctatt tacagcagct gacgggtact taggaatcgc tattatctgg ggagcgatgg
    54121 cgctgttttg gtttgtcggt gttcatggac cgtcgatcgt ggagccggca attgcggcaa
    54181 ttatctatgc caatgtggaa accaatctgc aattgttcaa ttccggtgaa caagcttcta
    54241 aagtactgac ggtgggttta gggaattttg taggaactat gggaggaact ggggcaacat
    54301 tggttgttcc ttttatcttc ctactctttg ctaagtctaa gcagttgaag gcagttggga
    54361 aagcttcctt tattccagta agtttcgctg tcaacgaacc attgctattt gcggcaccca
    54421 tgattttgaa cccttatttt tttattccat ttttgttaac acctgttgta aacgtttgcc
    54481 tgttcaagtt ttttgtcgat gtattgggca tgaacagctt tatgtacgtt ttgccttggg
    54541 caactccagc accgatcggt ttggttctag gaacgggcat gggtatctta gcttttgttc
    54601 tagcagcggt tctaatcgtc gttgacttcc tgatctatct accattttgc aaagcatacg
    54661 atgctgtctt agtagagaaa gaagcacaaa aagcagaggt gatcgcaacc gaggaaggtg
    54721 cttctgccga tgtacgtgag gaagtacctg tggcagcgag tcaagttatc agcgatgcaa
    54781 ataaagaaat caatgtgttg gtactttgtg ctggcgcagg gacaagtgcg atgttagcta
    54841 atgctttaaa aaaaggtgca tctgaatcga aagcaccgat cagtgcaatg gcgggtgctt
    54901 atggttctca ttacgaaatg ctgcaggatt ttgatatggt ggtcttagca ccgcaagtca
    54961 attcttacta tgatgatatc aaagaagaca ccgatcgctt aggaatcaag ctggttgcga
    55021 caaaaggagc agaatatatc ggattaacga gagatcctga aaaagctgtt cagtttattc
    55081 tgaaccaatt tcaataaagg aggagccata atgaaaatgg gaatttggtt gcgtaaagct
    55141 gttttatttg cagctgtgtt aggggctttg ggggctgttt caaaaactgt tgaagcatct
    55201 gccagcgaat ttattcgcgg agcagatatt tcgatcctgt cagatatgga aaaatctggt
    55261 gcaaaatatt atgaagacga tatttcaaaa gatgccttag agattttaaa aaataatggt
    55321 gtcaactatg ttcgactgcg tttgtggcag gatccttata atagtaatgg agaaagttat
    55381 ggagcaggga caaatgatct ggaaacgacg attgaccttg caaaacgagc aaaaaatctg
    55441 ggacttaagg tgctgctgga ttttcactac agtgattttt gggttgatcc tgggaaacag
    55501 aatcttccta aagcatggca aggtctgacc tttgaagaaa tgaatacggc attgtacgac
    55561 tatacaaaga acgttctgtc ggaaatgaag cagctggacg tttatcctga tatggttcag
    55621 atcggcaatg aactgaatag cggaatgctc tggccttatg gcaagtcttg gggagaaggc
    55681 gggggagaat ttgatcgatt ggctgctttt ttgaagtctg gtatccaagc tgttcgagac
    55741 actcaaccta aaacaactcc agtaatgctc cacttagctg atggtggcga tacaggagca
    55801 tttacttggt ggtttgatga aatcacgagt cgaggtgtgt catttgattt aattggagtg
    55861 tcgtattatc cgtattggca cggttcaatg aatgaacttc aaaccaatat gaatgcgatc
    55921 agccaacggt atggtaaaga agtgatcgta gttgaaacag cttatgggca tacaacagcg
    55981 aatgccgata ctatgccaaa tgcttttggt gaagccgaag cagctgcggg gggatatgaa
    56041 ccaacaccga caggacaagc agagtatttg ctggatcttg ccgatcggat tcaggcagta
    56101 ccgaataatc gcggggcggg cttcttctat tgggaacctc tttggtacaa cggaaatgtg
    56161 agttgggcaa cacaagcagg tatgaattat ctcagtgttc aatccactat gggaaacgaa
    56221 tgggacaacc aagcgatgtt tgattttgct ggaaacgcct tgccaagctt gcgtgcgttt
    56281 aaacaagcag gggcgcaaat aaatctagtt aaaaatgcaa gtttcgaaag cgatggacca
    56341 acgaccagtc cttccaattg gcaaacctgg tttcaacaag gaaccgctaa gggtacgatc
    56401 aaaacggaag cgggcacttt ttttggggac tacaaactaa ctttttggca ggatcaagca
    56461 tacgaggcat cagcttatca aaatgttagt ggcataagca aaggaactta cacattgagt
    56521 gcctatgtaa tgtctggggg agagtttgat actaatcagt tatatatcaa aaattatggt
    56581 ggagcggaac taaatactgc ggttgttaaa acaagtgaat ggacaaaaat tacaatcaaa
    56641 gacattccaa ttacaacagg tgtttgtgaa attggggttt atagcaaggc ttcaggaaat
    56701 gcttggacga acgttgattt tgtttcattg gtgaaacaat agactgcgga tcgtttcgat
    56761 tcaagatcgg aggttccctt cagccacatc gttagcgtag aaggcaggaa tcgaacctgc
    56821 acctcgcctt tgccaaaaat aaccagaaac gatttccagt catttttacc aaaacgagta
    56881 aagcaccaga cttcatctac actttgtatt atgctaaaga gagttcaacg atttcgtaag
    56941 aagcaatgaa aaaattgcaa aaagttgtgc agataacata aagtttgttt aagaaagggt
    57001 aaccttagaa ttccgtcgtg aatatgattt gagcacttag atggatagaa aaaagttctc
    57061 ggaaaacagt tcgtttttcg agaacttctt tttatgataa gaatgaaaca aattaactta
    57121 tattatagtc tcttttggta gggaaccatc ttatttttaa tgaaaatcaa gcattttagc
    57181 tattgaagaa tgttgattta tagggattcc ccctccatat tatgttggct ctttattccc
    57241 actctgtttt caacgtaaag tgtataaaac agaatgcgat actatcaagg gagttaaaac
    57301 aatatacaga acagtaaaac actataaata aaaataaaag tgcaattttt gcacctaatc
    57361 atactctgtt tatatatgaa aactagattc tgaatccaat atttggttaa cgagaggcgt
    57421 tcgaatttga acgtctttta tatattactt tcaaataaat atgaggtaga atactatcta
    57481 ttttcttttt aacccaattg ttataatgga gagtgtaaaa tattttgtgt aaatagaaaa
    57541 aaggaagtcc cttctgtaga atagagttac cacaacacat tcacagaaga gaggacttcc
    57601 ctatgaacga ttttactaca gaaattctaa agactctagc gaacaaaggc gatttgaatg
    57661 aattattccg tgtccatttg gagaaagcag tcaatacgct tctcaaaacg gagttaacgg
    57721 ctttcctaga ttacgaaaag tatgatcgca ttggttttaa cacgggtaat tctcgtaacg
    57781 gctcctatga ccgtacggtc aagaccgagt atggggaact tcatctccag attccgcgcg
    57841 accgcaatgg tgagttcaag caacagactg ttcctgctta tagacggacg aatgacacgt
    57901 tagaggagac cgtcattcac ctcttccgaa aaggtattac catgtcggaa atcgcagact
    57961 tgattgagaa aatgtatggg cattactaca cgccccaaac catgtccaat ataacaaaat
    58021 catttacaga agaggtaacg gcgtttaatg ggcgggagct tcatgaccgt tatgctgcta
    58081 tttatatgga cgcaacgtat attccgttaa agcggaaaac cgtcgccaag gaagctattc
    58141 atatcgcagt tggcattcgc ccggacggat caaaggaagt attgagctat gcgattgcac
    58201 cgactgaatc catcacgatt tgggaggaaa ttttattgga ccttcaagag cgcggtttga
    58261 aaaatgtcct cctgttcatc acggatggct taaaggggat ggtaggagcg attagtcggt
    58321 tctatcccaa agctcgtttt caacattgtt gtgtacacgt ttcccgtaat atcagtcata
    58381 aagtgcgtgt cgatgatcgt aaggaagtct gtgatgattt taaaatggtg tatcaagcct
    58441 catctaaaga ggtggcgttg gaagcacgtg gtacttttgc ggaaaaatgg aaaaccagct
    58501 atccaaaagt ggttgaatcg attctttcga acgatcactt gctcactttc tatgatttcc
    58561 ccttggccat acgcaagagt atttattcta cgaacttgat tgaatccttt aataaacaaa
    58621 tcaagaaata cagccaccgc aaggaacagt tccaaaatga agagtcgatg gaacgtttct
    58681 tagtctcgtc ttttgatact tacaaccaaa aattcctagg tcgcagtcat aaaggtttcc
    58741 aacaggccga aggcgagctc gaacaaatgc taagccaact gattgagaat tagaaacaat
    58801 ctgcagtagg gaagaatcat ttacacaaaa ttattgacgc tcccttataa tgagaacttt
    58861 tactaacata atttatgata aacttactat ataatcatat taattaaata gttaggagat
    58921 ctgcttatgt ttatatctac tcttcaaatt cgaaatttta gaaattatga atccgaaatc
    58981 tttcgattcg ataatgagac aaatactatt ataggtgaga atgattcagg gaaaaccaat
    59041 gctcttactg cattgagaat cttattagat gatagttatt actatagtag taaaacacta
    59101 aaagaatcag atttttttca tggaattcaa aatgggtggc aagggcattg gattattatc
    59161 tctgcgacat ttgaaggaat cagcgaagaa gaatttgaca atgagatttg tgcttccatt
    59221 tctttaaatt ctgaaagtca aacaatctta gaagaattga tttcaaatgc agataaaggt
    59281 gtaggtagta tttctctatt tattagacct aacaaagcta ttagaaagca attatttgat
    59341 atttccactg aattagactc tcatcaattt aacgaattta gaaattctat tcgtctatcc
    59401 gactatgaat tttactacac atctaaatca aatctaaatt tctgtatcaa tgaaaattat
    59461 gataaattgg taggaagact caatgacaat atagctagta atcctgaaga agacgatgaa
    59521 gctctgttgg gctcaagaat tgacatgtca gatattttca agcatatttc ggttgtttat
    59581 gttgacgctc ttcgagatgt tcttagagaa atgaaaaaca atcgaaaccc agtcaaaaga
    59641 atcatggaaa caattgaatc aaaaatatca tcagataatg ttgagtcatt aaaaacaatt
    59701 atacagcaat taaatgagac tattaccagt gttcctgaaa ttaggaaaat tggcgaaaat
    59761 attaatcggc aactaaatag cataattggt tcagtgtatt ctcctaatct tcttctttcc
    59821 tcaactatgt cagatgatat gggttcttta gcaaaatttc tttcaatgaa gccagaacaa
    59881 aatatcgact tagacttact agggttagga catctaaata tgatttattt agctttgaaa
    59941 atagtcgaat ttgaagcgtg tcgttcaaga gaactactta atattatgtt gattgaagaa
    60001 ccagaagctc atattcatca tcatattcaa aaaactctgt tcgaaggatt aaatcttcaa
    60061 aaaaactata ctcagattct catgaccaca cattctgtac atttagctga agtgtctgaa
    60121 atatctcgga tgaatgtatt aaaatcgttt aatggcaaat ctatcgttat gaatccagca
    60181 aataatctga actcatttgc taaagaaaag ttaaaaaaga acaatctaaa tctaataaac
    60241 gcagtagaga gatatttaga tgttaaaaga aatggattgc ttttttctaa aggtgttatc
    60301 ttagttgaag gagatgctga agaaatactt attcctcaaa tagtaaaaaa attatttggt
    60361 ataaacttag acgaacttgg aataggtttg attaatgttg gtagtacttc gtttgaatat
    60421 atcgctagct tgtttgacga tgatagaata cagagaaagt gtgctattgt aactgattta
    60481 gatgaacagg caatcccatc agaacatcga ttgtataaaa gcactgcaca agagaaaggt
    60541 caagcaagaa aagaaaaatt atcctccctt tttaatgaaa acaattgggt taattgtttt
    60601 tatgctaata caacatttga aattgagttt ttagatgtga ataaagaaaa tattctaact
    60661 tatgtcagtc caattataga tgacgcattc aaagataaaa aaacaataac tgcttataaa
    60721 gaagaaatac aaagtgaaca atatttagaa agaaatttag cgatgttaaa actagccaat
    60781 catgttggta aggggtggtt tgcaattgag ttaggtgaaa aaattgactt tttaatcaaa
    60841 attcctaagt atattcttaa tgctattgct tttgcatgtc aggaaatagt agatctctca
    60901 atttataaaa aaattctact ccatacaatc gacttgtacg aggaaactac agaattgtca
    60961 gctttatcag ctagtttaaa aacaagtgat acagctgatt tgaatatagc aataatttct
    61021 ttattagagt actttggtaa agatgaggat gttgtgtatc taatcaatca gatagaaaat
    61081 tacacaaaaa tactttatgc tgaggtttca aaatgacaaa tatcttcgaa aaaatcgtaa
    61141 atgatttaaa tttagaacaa aaagatgttg tggaaagtga agataacctt tatgtaaatg
    61201 catgtcctgg gagtgggaaa acaagggtac ttacaaggaa aattgcttac caagcaatta
    61261 aacacgatgg atcactaaaa agaataattg ctatcacata cactaataga gctgctgaag
    61321 aaattaagga acgcctaagt ttacttagta tagatgatga tattaatatt tgggtgggga
    61381 caatacatca gttttgtctt gaatttatta tttatccttt taaaatgaat ctctcaagag
    61441 tatcaaaagg atttacaatt attgatgatt atactcaaag agcttacgtc agccaaatta
    61501 ataatatgct gaatttaaat ctcaaaacgt atgaactgaa caaaattgat ttgtcacttt
    61561 ctcatgattt taaaattaat gaagttcagt atactcaagt ttctgaaatg tatcacacta
    61621 tgttggaaaa aaataaagaa attgattttg atatgatttt actagtagcg tataaaattt
    61681 taactgtaaa cagtaacgtt gcacgtaata ttg
//
LOCUS       DAIGUC010000009        61534 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.009, whole genome shotgun sequence.
ACCESSION   DAIGUC010000009 DAIGUC010000000
VERSION     DAIGUC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.009"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(59..187)
                     /locus_tag="NOB46_000573"
     CDS             complement(59..187)
                     /locus_tag="NOB46_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI1057545.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="NOB46_000574"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="NOB46_000574"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI1057546.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="NOB46_000575"
     CDS             complement(1674..2729)
                     /locus_tag="NOB46_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI1057547.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="NOB46_000576"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="NOB46_000576"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HCI1057548.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="NOB46_000577"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="NOB46_000577"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HCI1057549.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="NOB46_000578"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="NOB46_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HCI1057550.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="NOB46_000579"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="NOB46_000579"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCI1057551.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="NOB46_000580"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="NOB46_000580"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HCI1057552.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="NOB46_000581"
     CDS             10491..12050
                     /locus_tag="NOB46_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HCI1057553.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="NOB46_000582"
     CDS             complement(12161..14092)
                     /locus_tag="NOB46_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1057554.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="NOB46_000583"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="NOB46_000583"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI1057555.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="NOB46_000584"
     CDS             complement(15021..15773)
                     /locus_tag="NOB46_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1057556.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="NOB46_000585"
     CDS             complement(15932..16141)
                     /locus_tag="NOB46_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057557.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="NOB46_000586"
     CDS             complement(16152..17480)
                     /locus_tag="NOB46_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057558.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="NOB46_000587"
     CDS             17616..17771
                     /locus_tag="NOB46_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057559.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="NOB46_000588"
     CDS             complement(17845..18432)
                     /locus_tag="NOB46_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCI1057560.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="NOB46_000589"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="NOB46_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCI1057561.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="NOB46_000590"
     CDS             complement(20012..21301)
                     /locus_tag="NOB46_000590"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCI1057562.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="NOB46_000591"
     CDS             complement(21455..22387)
                     /locus_tag="NOB46_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057563.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="NOB46_000592"
     CDS             complement(22544..23203)
                     /locus_tag="NOB46_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI1057564.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="NOB46_000593"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="NOB46_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCI1057565.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="NOB46_000594"
     CDS             complement(24244..24534)
                     /locus_tag="NOB46_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057566.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="NOB46_000595"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="NOB46_000595"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCI1057567.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="NOB46_000596"
     CDS             complement(26821..28176)
                     /locus_tag="NOB46_000596"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCI1057568.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="NOB46_000597"
     CDS             complement(28200..29369)
                     /locus_tag="NOB46_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057569.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="NOB46_000598"
     CDS             complement(29366..30253)
                     /locus_tag="NOB46_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCI1057570.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="NOB46_000599"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="NOB46_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCI1057571.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMTIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="NOB46_000600"
     CDS             34320..34841
                     /locus_tag="NOB46_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI1057572.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="NOB46_000601"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="NOB46_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="NOB46_000602"
     CDS             complement(36284..36940)
                     /locus_tag="NOB46_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057573.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="NOB46_000603"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="NOB46_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCI1057574.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="NOB46_000604"
     CDS             complement(38477..39475)
                     /locus_tag="NOB46_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCI1057575.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="NOB46_000605"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="NOB46_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCI1057576.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="NOB46_000606"
     CDS             complement(40491..41222)
                     /locus_tag="NOB46_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HCI1057577.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="NOB46_000607"
     CDS             complement(41226..42491)
                     /locus_tag="NOB46_000607"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HCI1057578.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="NOB46_000608"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="NOB46_000608"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCI1057579.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="NOB46_000609"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="NOB46_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCI1057580.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="NOB46_000610"
     CDS             47833..49335
                     /locus_tag="NOB46_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HCI1057581.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="NOB46_000611"
     CDS             49337..50074
                     /locus_tag="NOB46_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1057582.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="NOB46_000612"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="NOB46_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCI1057583.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="NOB46_000613"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="NOB46_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCI1057584.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="NOB46_000614"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="NOB46_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCI1057585.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="NOB46_000615"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="NOB46_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HCI1057586.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="NOB46_000616"
     CDS             complement(55574..56740)
                     /locus_tag="NOB46_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCI1057587.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="NOB46_000617"
     CDS             complement(56756..56983)
                     /locus_tag="NOB46_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCI1057588.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="NOB46_000618"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="NOB46_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="NOB46_000619"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="NOB46_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59476..59637)
                     /locus_tag="NOB46_000620"
     CDS             complement(59476..59637)
                     /locus_tag="NOB46_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057589.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="NOB46_000621"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="NOB46_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61417
                     /locus_tag="NOB46_000622"
     CDS             60827..61417
                     /locus_tag="NOB46_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCI1057590.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17078 a        13211 c        10646 g        20599 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagtcat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacatgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt cata
//
LOCUS       DAIGUC010000010        59666 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.010, whole genome shotgun sequence.
ACCESSION   DAIGUC010000010 DAIGUC010000000
VERSION     DAIGUC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.010"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(450..1760)
                     /locus_tag="NOB46_000623"
     CDS             complement(450..1760)
                     /locus_tag="NOB46_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCI1057591.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1772..3190)
                     /locus_tag="NOB46_000624"
     CDS             complement(1772..3190)
                     /locus_tag="NOB46_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1057592.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3430..4998)
                     /locus_tag="NOB46_000625"
     CDS             complement(3430..4998)
                     /locus_tag="NOB46_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI1057593.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5002..5412)
                     /locus_tag="NOB46_000626"
     CDS             complement(5002..5412)
                     /locus_tag="NOB46_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HCI1057594.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5409..6332)
                     /locus_tag="NOB46_000627"
     CDS             complement(5409..6332)
                     /locus_tag="NOB46_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HCI1057595.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6329..7207)
                     /locus_tag="NOB46_000628"
     CDS             complement(6329..7207)
                     /locus_tag="NOB46_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HCI1057596.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7194..8530)
                     /locus_tag="NOB46_000629"
                     /pseudo
     CDS             complement(7194..8530)
                     /locus_tag="NOB46_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
     gene            complement(8533..9636)
                     /locus_tag="NOB46_000630"
     CDS             complement(8533..9636)
                     /locus_tag="NOB46_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI1057597.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9710..11218)
                     /locus_tag="NOB46_000631"
     CDS             complement(9710..11218)
                     /locus_tag="NOB46_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1057598.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11184..11876)
                     /locus_tag="NOB46_000632"
     CDS             complement(11184..11876)
                     /locus_tag="NOB46_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI1057599.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11898..12872)
                     /locus_tag="NOB46_000633"
     CDS             complement(11898..12872)
                     /locus_tag="NOB46_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1057600.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13172..14044
                     /locus_tag="NOB46_000634"
     CDS             13172..14044
                     /locus_tag="NOB46_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1057601.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14502..16700)
                     /locus_tag="NOB46_000635"
     CDS             complement(14502..16700)
                     /locus_tag="NOB46_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057602.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16932..17924
                     /locus_tag="NOB46_000636"
     CDS             16932..17924
                     /locus_tag="NOB46_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1057603.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17984..19405
                     /locus_tag="NOB46_000637"
     CDS             17984..19405
                     /locus_tag="NOB46_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HCI1057604.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19398..20897
                     /locus_tag="NOB46_000638"
     CDS             19398..20897
                     /locus_tag="NOB46_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HCI1057605.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20936..22330
                     /gene="uxaC"
                     /locus_tag="NOB46_000639"
     CDS             20936..22330
                     /gene="uxaC"
                     /locus_tag="NOB46_000639"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCI1057606.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22489..23172
                     /locus_tag="NOB46_000640"
     CDS             22489..23172
                     /locus_tag="NOB46_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HCI1057607.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23174..24010
                     /locus_tag="NOB46_000641"
     CDS             23174..24010
                     /locus_tag="NOB46_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI1057608.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24021..25775
                     /locus_tag="NOB46_000642"
     CDS             24021..25775
                     /locus_tag="NOB46_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057609.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26051..26392)
                     /locus_tag="NOB46_000643"
     CDS             complement(26051..26392)
                     /locus_tag="NOB46_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI1057610.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26460..28631)
                     /locus_tag="NOB46_000644"
     CDS             complement(26460..28631)
                     /locus_tag="NOB46_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI1057611.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28800..29699
                     /locus_tag="NOB46_000645"
     CDS             28800..29699
                     /locus_tag="NOB46_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI1057612.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29770..30627)
                     /locus_tag="NOB46_000646"
     CDS             complement(29770..30627)
                     /locus_tag="NOB46_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1057613.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQGFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30612..33314)
                     /locus_tag="NOB46_000647"
     CDS             complement(30612..33314)
                     /locus_tag="NOB46_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCI1057614.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33327..34616)
                     /locus_tag="NOB46_000648"
     CDS             complement(33327..34616)
                     /locus_tag="NOB46_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HCI1057615.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34766..35812
                     /locus_tag="NOB46_000649"
     CDS             34766..35812
                     /locus_tag="NOB46_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1057616.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35814..37967
                     /locus_tag="NOB46_000650"
     CDS             35814..37967
                     /locus_tag="NOB46_000650"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HCI1057617.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38440..39891)
                     /locus_tag="NOB46_000651"
     CDS             complement(38440..39891)
                     /locus_tag="NOB46_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1057618.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39888..41612)
                     /locus_tag="NOB46_000652"
     CDS             complement(39888..41612)
                     /locus_tag="NOB46_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1057619.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41605..42219)
                     /locus_tag="NOB46_000653"
     CDS             complement(41605..42219)
                     /locus_tag="NOB46_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI1057620.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42564..44021)
                     /locus_tag="NOB46_000654"
     CDS             complement(42564..44021)
                     /locus_tag="NOB46_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1057621.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44062..44982)
                     /locus_tag="NOB46_000655"
     CDS             complement(44062..44982)
                     /locus_tag="NOB46_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1057622.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44994..45941)
                     /locus_tag="NOB46_000656"
     CDS             complement(44994..45941)
                     /locus_tag="NOB46_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1057623.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46420..47139)
                     /locus_tag="NOB46_000657"
     CDS             complement(46420..47139)
                     /locus_tag="NOB46_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI1057624.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47188..48834)
                     /locus_tag="NOB46_000658"
     CDS             complement(47188..48834)
                     /locus_tag="NOB46_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI1057625.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49013..49603
                     /locus_tag="NOB46_000659"
     CDS             49013..49603
                     /locus_tag="NOB46_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1057626.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49695..51200
                     /locus_tag="NOB46_000660"
     CDS             49695..51200
                     /locus_tag="NOB46_000660"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HCI1057627.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51284..52636)
                     /gene="celB"
                     /locus_tag="NOB46_000661"
     CDS             complement(51284..52636)
                     /gene="celB"
                     /locus_tag="NOB46_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI1057628.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52636..53154)
                     /locus_tag="NOB46_000662"
     CDS             complement(52636..53154)
                     /locus_tag="NOB46_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057629.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53170..53496)
                     /locus_tag="NOB46_000663"
     CDS             complement(53170..53496)
                     /locus_tag="NOB46_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HCI1057630.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53509..55488)
                     /locus_tag="NOB46_000664"
     CDS             complement(53509..55488)
                     /locus_tag="NOB46_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI1057631.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55509..55823)
                     /locus_tag="NOB46_000665"
     CDS             complement(55509..55823)
                     /locus_tag="NOB46_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HCI1057632.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55991..56284
                     /locus_tag="NOB46_000666"
     CDS             55991..56284
                     /locus_tag="NOB46_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCI1057633.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56362..57474)
                     /locus_tag="NOB46_000667"
     CDS             complement(56362..57474)
                     /locus_tag="NOB46_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI1057634.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57861..58040
                     /locus_tag="NOB46_000668"
     CDS             57861..58040
                     /locus_tag="NOB46_000668"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057635.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58234..58404
                     /locus_tag="NOB46_000669"
     CDS             58234..58404
                     /locus_tag="NOB46_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1057636.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58828..>59666)
                     /locus_tag="NOB46_000670"
     CDS             complement(58828..>59666)
                     /locus_tag="NOB46_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1057637.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        17828 a        12197 c        10436 g        19205 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt tcgatttcgt
      181 ttttcgaaat ctttcagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac
      241 ttttttgaag tttttttcga tagaatcaag cttcgcaagt ggttcttttt aacgacttag
      301 ttatcttatc acgtctaaaa acatgtgtca actctttttt ggaattttca taaaatgttt
      361 caatgaagcg cgacaacgtt gtttaatata tcattaaaaa aaataaaggt caagctaaaa
      421 tattatttaa gcttgacctt attataattt caacgattgt caaaagtatt gtttgcagct
      481 gtgttgccag tttctataga taaatcacag cttttgaaac ataagttttg tactgcttcg
      541 attcgcccga attcttttgc agttatttgg caatgagaaa agcagacatc ttctataggc
      601 ttttcaggaa atgctactaa atcaaaagct cgggaaggaa gtgagtaacc tggagaaagg
      661 catgcctgta cgtttttgat gtgtatgtct ttgactttcg tcatttgctt tgattcaggt
      721 atttcttcag ccactgcttg ccaactttct ggcatttgag caaggtcatt gctatttttt
      781 ctattgtatt cattatgcca gtccattatc caagaaaaag gaaattgtac atcaatcata
      841 ttcagatttt ctaccctgat attttcgatc actccccctc tttcttttga agatttcatt
      901 cgaataccac agtctgactg aaaaaaatcg atatcgtgaa tatatacgtc actaactcca
      961 gcactaactt cgctaccaat agttacaccg tatcctgaac ggattttaca tctagcaacc
     1021 tcgattcttg atgattttcg attgactctt gcaccattgc catctctgcc agacttaata
     1081 gcaatacaat catcaccaca ggccaaatca cattcataga cacgcacatt tgttgaagaa
     1141 tcaatatcaa tcccatctgt acttggtcca tcattgttgc ggatgattac tttttctact
     1201 aatacatcgt tagaataagt gatttgcaag ttccaaaaac ctgatttctg aaaaatcaaa
     1261 tcacgaacaa caacatgttc tgcatgatac agtaaacaag cgcgtggacg tttaatagca
     1321 taatccgcaa tccaacgaag tcccttttga tcgtattcag ctcttgtccc gcttttttga
     1381 tcttttcccc aatacagctc ccaccaatgg tctccttgac cgtcgattat tccttttcct
     1441 tctataagaa tatctttcgc cgagagaaca ttcaaaatcg ctgctggcca tttcatttct
     1501 acgccggcta ctcgtgtatc gatttctgga aatgcttcga tatctgttct ccccttgagg
     1561 actgcacctt cttcaaagat aagatgactc ttatctttta aaaaaagggc tccgactaaa
     1621 taaatgcctt ttggaataaa tacaggtaag tgttctttcg caccttgatc gattgctttt
     1681 tgcagtatta ttgtatcatc ttgttgagtg tcgtttgttt taaagttcaa agcattgata
     1741 atcccttttt ttgtccgcaa tacgtttctc cctatctttc attgattttt ttcaattctt
     1801 caccaataaa tacagttttt gaacgattca gtgggtaacc tactagcaaa atgattgcgg
     1861 atacaaataa gcagaatgct ggtaacaagt ttgccatcgt ataaatcctt tcttgtacta
     1921 aaactgattg gatggctcca cctgttgtag acgattggta accaatgagt gccagcataa
     1981 atccgcctac cgctcctgca catgcttgtc ctacttttct cgcaaaagaa tttactccat
     2041 atactgttcc atcttctctt aagcctgtct tatattgatg ataatcaatc acgtcagtaa
     2101 tgaatgccca gaccatcaaa ttgaataaac cagatcctaa agtagcgata aataaaagaa
     2161 tcagatatac ccatgcattt gttatatgaa ggaaatacat cagcaagtac atacatgaag
     2221 aagcaagtaa cgcaaatacg cttgcttcct ttttaccaaa taattttgtc agctttgtag
     2281 caaatggtgc taaaactact actgttccgt aagtaaataa aagagcaaca gacattgctt
     2341 gtttattatg gaagtaatca ttgaataaat aagtcatatt cgtcccagct aaaatctgat
     2401 tgatcacaat gaaaatgtca acaatgacta aaataatcag tgctcgatta gctaacaaac
     2461 cttttaccaa ctgagaagca gatacttttt cgtttttgac aactcttact ctttcagtag
     2521 tcaatttaca agttaacata tatgcgacaa atgctattgc agcacatccg attgaaatcc
     2581 aaaagaaatg attccctgaa acgacttgtt gtccactctt gttatgggta tacattaaaa
     2641 tcggaatgaa gaatcctgta gttgatccgc caatcgcaga accaatgctt cggaacgtgg
     2701 acaacgaggt gcggtcatta ggatttgagc taattgctgc tgccattgct ccatacggga
     2761 tattgattgt tgagagaaaa atcccataaa caatgtatga aacaaaaata taagcaatct
     2821 tcaccgtcat tggaagatgt tggacgaatg gcaaaaacaa aatgacagtc actaagcaaa
     2881 atggatactt catttttctg atccaaggaa taaatcggcc agtttctgtt aactctgaga
     2941 catcacataa tcttccaacc atcacatcag caaacgcatc caaaattctc gaaatcaaga
     3001 ataacgtacc tacgattgcc cctgaaacgc caagaacatt cgtataataa atcatcaaga
     3061 aactattgac taaacctaaa ataaaacagt tacctagatc accgaacatg tagcctatct
     3121 tatcggaaat cccaaattcc tttttttctt tttttattgt atttgctgta acagcatttt
     3181 gtgaaagcat ttgaattcct cctacctctt ctagtaaacg ttttcaaaat tataactctt
     3241 tttttcttgt ttttatattc acaatgttgg ctttttattg cattatcttg acagataaaa
     3301 aacaaaaaat aatctaaaaa cattgatgca taagattgat aacttttttt acataacaat
     3361 atatacaaac aaaaaaattc actaactagt gaaaataagt tagtgaacct catttattaa
     3421 agaattaaat tacagatgat cttttccatc atacttgaaa aactcaaaat cagcataact
     3481 tcctcttttt ttatttagat catgcactgc tatcccgata aaatttccag taaaccctcc
     3541 tgagagtata cacatgtttt tttgcggacc tactttcttc cattcttcag ttgatacgtc
     3601 tttcaaatga aactgtgctg tctctttctt tacagtgact ttcaaaaaag tcttcttttc
     3661 tgtgagtgga atcgtccaat cttctatttg tgctactccg ttttctgatt ctatcatacg
     3721 taggcatttt cccttgtcct cattccaagt aacataacaa taaatataat tggattcatt
     3781 taagtacagt accagtccag ccatctgatt aaaattatta ggcatgtatt caaatgctgt
     3841 ctccgcatca aaagtaaaat ccgtttgccg aatagctaac aaatgatgtt cgaaggtaga
     3901 ttgaagagat tcaccggaaa tcagacgtaa aaaacctggt ctacattttg tatcacacca
     3961 atcagcattt ggcaaaatgc gtctggcatt ccagttcttc tttagctctc cttcaaatgt
     4021 atccataaac tgatgatctt tttcttgttg tacctcttca tttgtctcaa tcattatttc
     4081 ttccatcgga gttgtctggc tatctttaag tcttaaccaa tcgtcggacg tccaatacac
     4141 ttcttgaata gcggtttctc ttcccaaaat agccgcaccg tttaatggtc tggtacaaag
     4201 atatgtcatg taccatcttc ctgacggggt ttgtactaag ctcccatgtc ctgtacattg
     4261 caatgtagaa gcaggtttgt cactagctgt cagcatagga aaaccaggat caagctcgta
     4321 aggaccagta atattctttg ctcggcaaac tgtaactgaa tgtcctcttc ctgtaccgcc
     4381 ttctgccgtc atcaaataat aatacccgtt acgaaaatac aaatgtggtg cctccgtttt
     4441 cgctaattct gtacctgcaa atattttata gatgggacca tcaagcttct tcttctctgc
     4501 atcatattct tgtaatacga taccgctgga tttattcggt gtgtccagac gataatccca
     4561 tagttcattg acaagccatt tttttcccgt ttcaagatca tggaacaaag aaggatcaaa
     4621 gccgttacta tttaaataaa ttggttcgga ccaaggacct gtgatctcag atgcagtgat
     4681 caaataattg tggacatctt taaacggacg gcctgcactt ttgacatctg tgtaaacaag
     4741 ataaaacaat ccatcagcat aactgatctg tggcgcccat atacttccat ttgtaggatt
     4801 tccttgcaaa gatacttgag tggtcaaaat atccgttgta tgtgaccagt tgactaaatt
     4861 tttcgactca tatactcgga ttcctggaag ccattcaaaa gaggagacaa taatgtaata
     4921 ccgctctttc actcttaata tattaggatc tggattgaat cctcttaaaa taggattttt
     4981 cactttgata gtctgcatga ttcaggctcc ttttctcatt cttactcgat ataaactgaa
     5041 tgccccagct gcgaaataaa aaaatgcaaa aggaaacgca ataaactgag tgccaatcaa
     5101 caatatgaat cctgttataa aatacaaacc agtggcagtt gttaagtatt ttcctttagc
     5161 agtcaaaaac aatgctactg ctaaaaaagc aagtgaaata aacaacacaa cggcaaacag
     5221 accagtcatg tcctgtaata atccaaatgt attttctaaa gacaaagttg aatgatctac
     5281 agcaagcgac tgataacttt ttttaaactc tgacgcagac atattactta aagtaactgc
     5341 taacccgcca aagaaaatca aagatagact gccaccgacc attcctagca atagttccca
     5401 ttttcttttc atttctgaac cccctgcttt tctaaatgta tccattcagg tcttttgatc
     5461 gatgtttcat aattgttatt acgttcagag aatttgacag tctgttcatt tttcttgtca
     5521 tcccaattat cccaaccagt tgggtgaaca tgcccaccta tcttacacgc ttcaaataag
     5581 acatttgcat acggacgcca cggtcttcct aaatagacgt ttctagtatc aggttctgca
     5641 gtcaaggtac agctttcaaa acgataccct gttttttgat ttttcggcgt agatgctgct
     5701 gtgatgtatc caggattttt actggctaag ctatggatat gacactgatg aaaaacggca
     5761 tctgccccac caaatatgaa atccaccgtt ccttcaatcc agcaatattc ataggtctga
     5821 cgacaatact caggattggc agaagccggt gtacaaaaag gagtaccatc tttttgcaaa
     5881 tcaggcaacg gacccgtgca taaggtatcc tgataaccag atagtcgaca gttttttaaa
     5941 gatacgcgat ctcctgaatt gaataaagca acagcctgtc ctaccttttc tcctggacct
     6001 gctgtatttt cgatgtgaag attttctaat acgacattcg atccttctaa gaaaaaagta
     6061 gcacttcgga aagtccctaa ctggctaccg tcaagatact cctgttttgc aaaacgatta
     6121 ccggagataa ctactgttcc tgctcccaca agtttaaaat tggataatct gctttctata
     6181 tattcatcat atcttccttc ttttactatc aagacctttg gatggctatc cggcaggcct
     6241 gccaaataat cgattccttc ttggatagtt tcaaaatccg tcggggtatc tatagcattc
     6301 tttccaatta tcagtttgtc tttcatcctc ataaatgctc ccttatgaat tgtttccaaa
     6361 tatttctcat ttcttgtgtt tccatatgac cgcctgttaa agaaaaagaa gaaaagtttt
     6421 ctggactacc cattgattga tactttttgt ccagcccttt tctcagcttc agtacgcctt
     6481 cgtccaagca catcgtatcg ttttttccaa ctaagctaag acgagggcgc ggagcgattt
     6541 tttcttggat tgctaacgtt gtataagctg tcaatagatt tggcacatag taataaaacc
     6601 catgatgatc taggcggcga tgtagcaaaa gtatttcgat gtccacctgt gccgctagat
     6661 caatacaaac tttgacacga gaatccaatg ctgtcaccca ccagcttaat aagcctccca
     6721 tagaaagacc aatcgttgcg agccgttgag tatctgtgtc ttcccttgtc tccaaataat
     6781 cgatcaagct gatcacatca taaatacgca ttccccataa cgtttttcct gttaataaaa
     6841 attgtttgaa caactcgctt tcagaaatac ctccgcgttc ttcaaatccc caagcatcaa
     6901 tcgaccaaac agcatatccc attcctgtca gtacttctgc aaaagatgga gaagctaagt
     6961 aaggagcacc atggatcaat tcacttttcc cgactgaaaa atctccgccg tgagaatgca
     7021 ggtaaaggac cggcggaaac ggtccttctt tttctggata agcatagagg gctggtactg
     7081 tttccaattc atttaagtac aattgatagt attcaagcat aaaaccgttt tgtttttctc
     7141 ggtataatcg ttttccacta ggggtatgtc tgctagatgg agcacctaaa aaatcattca
     7201 actgcataag caaagttttt acgaacaacc agttcatcca tattttctga ttgatttgat
     7261 tggaatttct caatactgat ttctttagta ttttctaata gaaatgctgg tccctcgtga
     7321 ttttcaatcg acatctggtt aaaggaaacc ttacccgcaa agccaatata aaatccttgt
     7381 ctgctcattt cctctattcc tgtcatcata gcaggaacac cgggaactgc atcttgggcc
     7441 atcgagacat cgatattgtc aaatgtgatt tcttgtatga attgttccgc taatccataa
     7501 ataaaacctg cagaagcatg gacattcctt gccgtgatat tcgaaaaatg gatccttctg
     7561 aatgctggtg tccgttcatc tatcggataa gccttttttc ccatacatac ggttctttcc
     7621 ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca ttatccatga
     7681 ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta gatttcaatc
     7741 gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta cgaatactac
     7801 cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg caatttgtga
     7861 tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc ttgattgcaa
     7921 tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg catgattctg
     7981 gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag ttatcaaacg
     8041 ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc aatttaatat
     8101 ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga ggataagcga
     8161 gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca tctaatgtac
     8221 cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa gcataaactt
     8281 ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga tcgtcagaga
     8341 atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa aataaagctc
     8401 ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt gctgcagcat
     8461 caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca aatgtcaaaa
     8521 tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg caccaacgcc
     8581 tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac catctcgctg
     8641 atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc agccttcttt
     8701 tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt gtggaagcca
     8761 ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa caaacatact
     8821 actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta cttgatacca
     8881 tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt ctagaatttc
     8941 tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg ctgcagccat
     9001 caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt ttggatcagc
     9061 ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt ttggatcgaa
     9121 tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt tttcttcact
     9181 aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat ccaaccaaat
     9241 ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg gatggtttgc
     9301 caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg tttctttgta
     9361 caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt caacgctgta
     9421 gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta tgaaatcaaa
     9481 ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta cgacgccata
     9541 gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg ttctttccat
     9601 gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt taaaaattaa
     9661 aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat tactgtgccg
     9721 ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt gctttccagt
     9781 cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat tgcaccgtag
     9841 catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt gaatccaatg
     9901 gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga ttagagaatt
     9961 ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga gagcttgata
    10021 acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa ccatcatcat
    10081 tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca tcttcttcta
    10141 aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt acttgagatt
    10201 tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga taaccgccgc
    10261 cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga ataccttgac
    10321 ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt cttccttgtg
    10381 caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc aaatagccat
    10441 tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta tcaaattctg
    10501 gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa taagaagtga
    10561 aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa ccaactgtgt
    10621 cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact tcataaagct
    10681 catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt cgaatgacta
    10741 agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg tcgatactcg
    10801 cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt aaatattctg
    10861 atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt ttcaacatcg
    10921 caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt gttaatcttt
    10981 cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt ttttcttcga
    11041 tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt aaccaagtga
    11101 ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg ccgcatgcgg
    11161 caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct tttttcataa
    11221 attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc tgtatatgag
    11281 ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc ggaaaagaag
    11341 agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat cagataaatc
    11401 cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc gaataaaaat
    11461 gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat tgggaaaata
    11521 tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct aagataccaa
    11581 ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata tatccagctc
    11641 atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt cgtcaaagga
    11701 aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata cgatgcagga
    11761 ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa attcaaataa
    11821 accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg cagcatatct
    11881 ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc aatcttatta
    11941 gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc tgtactgaaa
    12001 cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat ttctgcaacg
    12061 cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc taatgtctga
    12121 ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa tgtaacatgc
    12181 catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa ctgtgtatcg
    12241 actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt ccagatcact
    12301 tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat tttttcaaat
    12361 cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa tacataagta
    12421 atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt ttgaatcccg
    12481 tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat tggcatcgga
    12541 aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa tgtaaagaat
    12601 gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact tcccattatt
    12661 cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg aagataccta
    12721 aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt attcgttttg
    12781 attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga tagcgtcagt
    12841 tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt gtgaatgttt
    12901 gctgcttatg acttcatgat agataactat ctgaattacg tatataatca tttttaccgt
    12961 aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa agtgtatttt
    13021 ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca cttagcatag
    13081 gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga aacagaaaca
    13141 tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta taggagaaag
    13201 aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct gtatcgttcc
    13261 ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg cgaaaaagtt
    13321 tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt ctacgccgac
    13381 catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga tcgtcagtat
    13441 gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg gtcgaggttt
    13501 cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc caacgttctt
    13561 agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc ctgtggctgt
    13621 taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg atagtttgga
    13681 agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa ttatgctgcc
    13741 attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt actggaacac
    13801 ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac agattctttt
    13861 acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg ttgatgtgat
    13921 tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc ctatgctgat
    13981 tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt ctgtcaaagg
    14041 gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct tcaagaaata
    14101 agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt atttttcgaa
    14161 gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca gccttgagcg
    14221 atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata agaagcgatt
    14281 ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag cctgtctctt
    14341 gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt tctttttgcg
    14401 tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt ctaacttctt
    14461 ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata tttttttcga
    14521 tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt ttgcggattt
    14581 cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt caaccatttt
    14641 tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc tgtttccttt
    14701 ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat cacatctaaa
    14761 gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga caaattttta
    14821 aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa ttgttctaaa
    14881 acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata aatttgtttc
    14941 atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac gagttcattg
    15001 atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc aaacaatgca
    15061 tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat ggcttcaaac
    15121 aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc agcaggaacg
    15181 atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata cagggcttct
    15241 tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt actgatgcct
    15301 atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg gcaatactcc
    15361 atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt ggcttgcatt
    15421 tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc cgtgatcatg
    15481 ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc taacagatcg
    15541 atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa ttgctgcaac
    15601 cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac aaatagcgtt
    15661 tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc tcctatgatc
    15721 cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt tgatttaaga
    15781 ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa taagtaggaa
    15841 agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat tctcagattg
    15901 cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca attattataa
    15961 tctgatttca gtactatata cgttttatct ttttctctta tcactttcag ctgattgtaa
    16021 tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt ctgagtagta
    16081 aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc accaacaact
    16141 tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc tttttcaaac
    16201 attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa taaattattt
    16261 ttgttattta tgtacttctg ttgatacttt tcaatttcct cttcggtcag ttgactcaac
    16321 gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt attatcatcc
    16381 ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt ggagtaatct
    16441 gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc atacgtagaa
    16501 aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg cctgagcaaa
    16561 ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg gtaaatgaat
    16621 aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa tattttataa
    16681 aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag gctttcattt
    16741 ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa gaatagcata
    16801 attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat caaagatcta
    16861 ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga aaaagtaagg
    16921 aaaatgatgg aatggtaacg atcaaagatg tcgctaaagc agctggcgtt tctcatacga
    16981 cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa caaaaaatac
    17041 gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt ttagtgaatc
    17101 aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact tcatcaaatt
    17161 tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac agtttatctg
    17221 ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac gatggactga
    17281 tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa gaaaaagaat
    17341 ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac gtcactgccg
    17401 atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga catacgaaga
    17461 tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa aaaggggtat
    17521 tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta acaggagatt
    17581 acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct gacctgccta
    17641 ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct gtacatttag
    17701 ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct ccagtcgtct
    17761 cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg tgtcaagaag
    17821 gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct aaaattgagc
    17881 tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca agtaatttta
    17941 tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa aactgacaaa
    18001 agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg aaggcaattt
    18061 tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat tgtttaaagg
    18121 taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga accagcaaga
    18181 taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg atacttccga
    18241 gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg cttatctatc
    18301 tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg caggaatcca
    18361 attcgtggag actgataatt taacagatac tcccccacag agcctcccgg gcaaactgac
    18421 agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca ttccttgcga
    18481 actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg cagaaaaatg
    18541 ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct gttgtagttt
    18601 agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca atcaacggca
    18661 taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg tgatcgaagg
    18721 gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg tcatcatcac
    18781 agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac cgcatacagc
    18841 gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa tgaaagatcc
    18901 tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta tgctttcttt
    18961 acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct tgaatccttt
    19021 tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca gcacccgtct
    19081 gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt taatcactgt
    19141 ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac atgatgatga
    19201 aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta ttcctcgatt
    19261 attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg tgacagatac
    19321 agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat tacaagaaat
    19381 gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta aatcgacgag
    19441 acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg attgatcagc
    19501 aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg ggtgatttga
    19561 aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg acagacgtaa
    19621 ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt gaattggatt
    19681 atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga acatttcaag
    19741 gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta gtacctaccg
    19801 ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa aaacatccag
    19861 atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt tcgcagcttg
    19921 gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat cccaatgccg
    19981 gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa ttcaaaaaaa
    20041 ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat gtttacgatg
    20101 agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa aatgaccagc
    20161 gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt tctgatggtc
    20221 tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg attgctcaag
    20281 gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa gtattgatgg
    20341 cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat gacttcaaac
    20401 agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt aataaagcag
    20461 gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca ggaagctctc
    20521 ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt agtttattgc
    20581 aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat tgccagttgg
    20641 tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg gtcaaggtat
    20701 ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat gcaggcgtct
    20761 tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc atcgctgtag
    20821 ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc atttttaaaa
    20881 acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa gatttatgtt
    20941 tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc attcctacgc
    21001 aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa tttacgaaaa
    21061 caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca aatggcgctt
    21121 gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg attttgaaaa
    21181 atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt acagttggtc
    21241 acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag aaaatgcaga
    21301 gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc gtcgggaaat
    21361 cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag acgacttgca
    21421 ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt cattccgtcc
    21481 agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac tactggaaga
    21541 agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag ggcagcggat
    21601 agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca tcttacgcta
    21661 taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag ctaacaaact
    21721 attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt tgacccactt
    21781 ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta actgtaatac
    21841 acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg atctttcttt
    21901 gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt tgccaaagac
    21961 gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga tgggctgttt
    22021 ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca acgatactcg
    22081 agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg ggaattttgt
    22141 cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat atttccgtcg
    22201 tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg aagatgaaca
    22261 acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt actttggctt
    22321 ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt gaaataacgg
    22381 aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt cttcttctct
    22441 tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat gcctactatc
    22501 catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc cgagacaggt
    22561 tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa ccaagcaaag
    22621 aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct agcttcacag
    22681 tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa aatccaagaa
    22741 gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt ttttgaatgc
    22801 gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg agattactta
    22861 gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat gcgtgcattt
    22921 gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga attgttccag
    22981 accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga tacttgtaaa
    23041 aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc tgataaagtt
    23101 gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa ttatttacaa
    23161 aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt tagatgttcg
    23221 aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata tccaatttgc
    23281 accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg ggagtgctgc
    23341 ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag gatgctatat
    23401 caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt tcaaacagca
    23461 aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg gtagtgtctc
    23521 tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca gaaattctat
    23581 cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg aagcagggat
    23641 caatcatcca atctataact atcagttagc taaacgttta atcgatgaag tagcttcacc
    23701 aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc atgctgatca
    23761 ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag cgcttcatct
    23821 caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca agggctgttt
    23881 agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt acgccactct
    23941 tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt ttatttacca
    24001 agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa aaatatcatg
    24061 caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt tttgccatgt
    24121 caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc gctattgcca
    24181 atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt tatttcaacg
    24241 cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt catgtaaaat
    24301 accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt atcaagaaaa
    24361 tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc cagtcaaaga
    24421 tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc agcggattaa
    24481 atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt cctgttgttt
    24541 tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt ttccgtaaaa
    24601 ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct gcaaaagtga
    24661 tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa cacgaaacaa
    24721 ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta gatatcctgc
    24781 aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg atttgtttga
    24841 ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc gtgatgtatc
    24901 agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg attcctacga
    24961 tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct ggcgatgtag
    25021 aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt tttgaggatg
    25081 tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct ctagaggtga
    25141 aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct acactcctta
    25201 acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat gatcagcctt
    25261 tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct caaaccactt
    25321 tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac gtatcaaaag
    25381 aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac cagcttcctg
    25441 atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc caaaagcaac
    25501 gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta gatgaagcaa
    25561 cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat tacctgacag
    25621 aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag gcagataaaa
    25681 tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa ctgttagctc
    25741 aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct atgacaagac
    25801 ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc tcggtcacaa
    25861 gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg taactcagag
    25921 ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc tatcggcaat
    25981 aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc tgttgtttca
    26041 taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata cggttcaagt
    26101 cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt acttcttctg
    26161 attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg aactcttgtc
    26221 cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg aacagtttgt
    26281 gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg aattctggta
    26341 attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac atgttatgcc
    26401 ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt tcaaaggggc
    26461 tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc ctgaacgcct
    26521 tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc atattgattc
    26581 aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc aacttgatct
    26641 gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc tgtttttgaa
    26701 gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac atttccactt
    26761 gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt cgaaatcact
    26821 acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc gaaattagtt
    26881 tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc agccgctgtt
    26941 ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc ctttgatatg
    27001 acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga atcaacgatt
    27061 ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact gtaagcaccc
    27121 gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc ataatactta
    27181 tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt ttgtaaaccg
    27241 atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc ttgatacatc
    27301 ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact ttgcggttcg
    27361 tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata tacgcttaat
    27421 ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa tcctctaaag
    27481 acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg atctaaagct
    27541 actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa tgcactgttt
    27601 tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata gattttatag
    27661 cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc atcgatcact
    27721 gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt gtcattaaga
    27781 tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat ttttccgttt
    27841 tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg gtgatcgatc
    27901 ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc agacagcgta
    27961 acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc ccataccccg
    28021 ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct gtacttcttt
    28081 tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg gtctaatgtc
    28141 agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc tgatgttccg
    28201 ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa cccgtgatgc
    28261 tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg agaaatcgcg
    28321 tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc gtttttctta
    28381 tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt tgcttgtttt
    28441 gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat cagcaaaatc
    28501 aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa ttgtccgaga
    28561 tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc taaaatgctt
    28621 tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt ttaccatagt
    28681 gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac gttagtgcaa
    28741 gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat gttttaaaaa
    28801 tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc acgatcactt
    28861 tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa tggttagttc
    28921 ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat caacaacctg
    28981 ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc gaagaaacag
    29041 attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt ttatatgaag
    29101 atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca aatgaaccga
    29161 cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa cagcaacgac
    29221 cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt gcaaaaaatc
    29281 catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat cggagatatc
    29341 aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa attggacgag
    29401 atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc gccttgacac
    29461 atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt ttggaaaccg
    29521 gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc gttggagacc
    29581 ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa ctgcacatga
    29641 tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta tgggaataga
    29701 aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct ttttgtgtaa
    29761 tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga taatcccact
    29821 ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt ccatataacc
    29881 acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct gattcattac
    29941 cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga tcagtgcttg
    30001 agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat cttgcccttt
    30061 gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac aatctttatg
    30121 ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa tatgtcccat
    30181 ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg caccgattcc
    30241 tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt gcttcaattc
    30301 cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt agcgttcctt
    30361 gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca aaacgtatcc
    30421 gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc cgattccctt
    30481 caattcataa cgatcaaaaa attcaaatcc ctgatccaat gtttcttctg gtgttgtggt
    30541 agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca caaattttgt
    30601 tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat tgtccgaatc
    30661 tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag cagattcaat
    30721 atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact agacatattg
    30781 aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt aattgcaaac
    30841 gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc atgatgtttg
    30901 atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt agagaatttt
    30961 tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag acactgtgct
    31021 tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag tagcgtcact
    31081 gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc gactgttaca
    31141 ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt cgtggggttt
    31201 tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact atctgcttcg
    31261 tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc tttcatctga
    31321 ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt catgattgtt
    31381 tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg aaattccaca
    31441 accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc catttcctgt
    31501 agaatactta tttttgctat ttccggtgta tctactaata cttttacttc agagttttct
    31561 ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata ctcatttcct
    31621 atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt tttgcgatct
    31681 tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt ttcgatgatt
    31741 cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc ttctacaagc
    31801 gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac tttgatcatt
    31861 cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa ttggacagtt
    31921 tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg atacttacgt
    31981 ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc gaatcttttt
    32041 ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc agtatttaca
    32101 atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc ggtcagctgt
    32161 tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa acgaggtatc
    32221 atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg atgattttgc
    32281 attaatgtct tccaagcata atctaattga tcatggggat agtttccact aacttcataa
    32341 gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt ggtattccat
    32401 tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc atccgtttct
    32461 tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt ttgaactgct
    32521 tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag ttcatttgcg
    32581 agatggattg cttttgatat atctttttgt accggttgat gatcaacacc attcatcatc
    32641 aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt ccaaaaggca
    32701 agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt ggcaaatagc
    32761 agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta ttgggaagaa
    32821 tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc acggccaaac
    32881 gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat atttccaaat
    32941 gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc ttccatgcca
    33001 atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg caagatataa
    33061 aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg tcttttttct
    33121 ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg aaaactgttg
    33181 aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat cagtcgcatg
    33241 tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga aatgatatat
    33301 actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa gtaatccatg
    33361 actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata attttcagga
    33421 ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc tacaagtaaa
    33481 ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat agctaatgca
    33541 atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc gtactttcct
    33601 tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag ataatcttcc
    33661 tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac attactgtca
    33721 tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt ttgccctttt
    33781 tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt caatttctgt
    33841 gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc cacataacct
    33901 aacacgacca ccgcaaacat attggatggt accagatatc cataacggca agtatcatcg
    33961 ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc tcgcccgtca
    34021 ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg agagtgttca
    34081 tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat aaaagattga
    34141 ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg tattgggtag
    34201 cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt tgtatgatct
    34261 gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg atcgatattg
    34321 atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc ctcatcttct
    34381 tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca catcgctgga
    34441 atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt tgtcaacaga
    34501 gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc cccacatttt
    34561 tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata agccactaat
    34621 aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc caattatgtc
    34681 tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat tatttgaata
    34741 tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa tatttaatga
    34801 tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac caactgaaaa
    34861 agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat tgactgaatt
    34921 agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta aatccgcttc
    34981 tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc ttcttccata
    35041 tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga tgcaagataa
    35101 acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag caaaagagct
    35161 aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac atcttgactt
    35221 actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa aaatctatga
    35281 gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg ctgcctctta
    35341 tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga ctcatccaca
    35401 atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg gtttgacttt
    35461 ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt atatcactaa
    35521 gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga ccatgaatct
    35581 cttgagacag catggttatc atatccctga agatttttca attatcggat ttgatgatat
    35641 ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt ttgaacagtt
    35701 aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc gaccatccga
    35761 tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat aaaatgaata
    35821 tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct aatgggaact
    35881 gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa actacggatc
    35941 aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac cgtcttaccc
    36001 atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg atcaatggaa
    36061 aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa gaaagtatat
    36121 tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct acattgatac
    36181 ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc ggtttacttt
    36241 tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg gaaggaaaaa
    36301 tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata ttgagatttg
    36361 aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac tcgatcccgt
    36421 tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt atcagctcgg
    36481 aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact taccttgctc
    36541 acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac catgatcaac
    36601 aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca caaacatttt
    36661 atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga tctataaaac
    36721 ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt tatcctcttt
    36781 attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg aacagctata
    36841 gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt atgcctggga
    36901 cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga gacttgatgc
    36961 ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat ccaaattatg
    37021 gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac taccacgaat
    37081 cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa gttgccaagg
    37141 tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac tatcaaaata
    37201 tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag ttcagagaac
    37261 cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg caaagcagct
    37321 ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt gagagatata
    37381 aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga ggatatggtt
    37441 ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta gctatttcaa
    37501 accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct gaaatggcac
    37561 agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg ggttaccctg
    37621 gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg ggattttatc
    37681 ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac aaggctgttt
    37741 tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg ccgcagcaac
    37801 aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat tttacccatc
    37861 aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct caccctaaga
    37921 aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa gaggttgtga
    37981 aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc tcatattttt
    38041 cgtttggttg gtcttattac cgcagatgca agcttttgaa caccgtttat tgagaggttg
    38101 tgaaatcagc gttctgacct gagtattaga gagacaaatg gcaaaatagt tcctcatatt
    38161 ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta gtggagaggt
    38221 cgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
    38281 tttttgcata aatttggctt aataccgaga aactggcttt tgaactccgt ttatcgagag
    38341 gtcatgaaaa agctgccttg cctcaagtaa taagaacagc ccaaaattag atttctagac
    38401 aattttttat aagttatttc attacattgg ctttttcttt tatgattctc cactgttttc
    38461 tcggtactct ttaggggatc tgccgacgat tttcttgaat aatttagaga aatacgtggt
    38521 gttgttgtag ccaatctcac ttgctatctc attgatgttt tgattactgt gcaaaagcag
    38581 ttgtttcgct ttttccatac gtaaatggtt caaataagct gaaaaacttt ttttcgtttc
    38641 ttttttgaac agctgtccta gatacatgac atttaaatgc aggttttctg acacttcttt
    38701 gagtgtaagt ggttcttgat aatgctggtg caggattacg attacttttt ccacattgtc
    38761 actgtacttt ttctgtctct gatgcttttt gatgaatgac agaagtagct gctgaagttc
    38821 ttgcaccgtt tttgcctgat ggattttttc gattccttgt aaatattcct catcttccag
    38881 atcaatcaat tcccgttgaa tctccataaa cagtaaaaaa ctggaatatc gtatatcttc
    38941 cggcatcatg gctgctaact gaaactgttc aaaaaaatca gtgatcattt tttgagcgac
    39001 ttccaattgt ttattttgca gcacgcgtct gaaacttgaa aaatcgatgg tttgatcttt
    39061 tgtttctgct tgtactgcgt aaaaaacatg ctcgtcttta tctccataaa attgatgcaa
    39121 ctgtagattg tctttcgctt gttggaatgt ttcagggatt ttgtccaaag aatctgtctc
    39181 ttccccgata ctgatcagcc attcctgatc aggaaagttt tcttgaacaa aacaacagaa
    39241 gccatcaact tcatctgcct ccaacaacaa cgtgatcaat acacggtctc cgtaatttcg
    39301 ttgatagtaa aagatttgtt gccgttcttg caaccatcta ttgataagag tatcatgagt
    39361 tcttgccagt tgaatcaata ctatcctatg ctgcttctca cttatttgtc ctattatttc
    39421 ttcttcactt atttcatcca attcttcatt caaccattga ctgaataaca gttcttgata
    39481 gatttcttgt tgattttttt gttcattttg ctgatctaac cgtgttttga ttttcttgag
    39541 gctttcaacc aattcgaact tattcacggg tttcatcaaa taattcacgg cgcctaattg
    39601 catacctcct ttcaaataat cgaattcttg gtatcctgat aaaatcataa attcaaaatt
    39661 atgacgttct ttttgagccg cttcaataaa ttccagtcca tttatttctg gcattgtcac
    39721 atccgttact actaaatcaa tctgtcgctg ttcaagtaca gctagtcctt ctttggcatt
    39781 ctctgctgtt gctactattt gaaagcctaa actttgccaa tcaattatct tttttaaccc
    39841 attcaaaatc atgtattcat catctaccaa taacacttga tacacgctca tccctccttg
    39901 aatgtaatag aaacggtcag tccacctgtc tcattattct caagcgacat ataataactg
    39961 ctgccgaagc tggcacgtaa acgttcattc acgttttgca gaccgataga accgtgaagt
    40021 tccactttag gatgagacag tttttcttca atctgtttta gccgtttttc agtcatccct
    40081 tttccattat ctttgatgat gatccttacc cgtttgcctt cctgcaagac tttgacactt
    40141 agcgcattat cgaatcgagt aaaatcaata ccgtgtttaa aataattttc aactaatggc
    40201 tggatcacaa atttaggtac ttcgatcttt tccaaatcag gatcgatcat aaaatgatag
    40261 gctactcgat taggataacg catttgatac aaatagacat atttttcgca aaagtccagt
    40321 tcttctttta aagtgatcgt tttctcttga ttcgtattgt ttcgaagcaa agcggaaaac
    40381 gcatacacaa catctgctaa ttcttcactt ccttcgctga ttgcatacat tcggatatat
    40441 tctaatgtat tatataaaaa gtgtggattg atctgtgctt gaagcgcccg catatgtgcg
    40501 tcttgctgtt tgatttctaa tttgtagatg tcttctacaa actgattgat gctatccaac
    40561 atttcgttga taccgattga aagttccttc agttcatatt ccgtgtttgt tatgtcgatc
    40621 cgcgtctcta aattccctgc tgctgtttga tccatggcct gcatgacgat agatacttgc
    40681 tgtgaatatc gtttgaatgt tttataaaga aagataagca gtatattgtc taaaataatg
    40741 ataccaatga tcagcggggc aagatttttt cccgtttcga tttttacact ttttttatct
    40801 agtacagcta atatacgata atcatcagac agttcttggt gttgaacaaa attgtttttt
    40861 tccagatcgt caatcggcaa ttgtgaattt ttcttcagac tctctgtgat gatcatttct
    40921 tgtctttcaa acgtttcttt agctatttta ttatcatgga atgtgtatag tcgatttgtc
    40981 gttccagaaa tcatgtataa agagagtcca ttgaatgacg ttagattttc taaaatcata
    41041 tctagttctt tcttttgaaa accaataaaa atacttcctg actcagctcc tccttgtgtg
    41101 ataggcaact tgatataaaa ggcgtctagt aattttggtg tccccttttt tatttcccca
    41161 cctttgtttt ctctagaaga ttcataatac tccggtagtt gattcaacac gatatatatc
    41221 gcacttagtt cttcataatt tgcgtagaga tctttgattt gatttgggaa agaaactaat
    41281 tcatcggtac tgttttgctg ttcgtataca tacatcagat actgatctat gggttttgtt
    41341 aagtaggtcg tcacattttc gatcttttcg gaattcccta caagctggtt tttgatgatc
    41401 ctactcaagg ttgttttatc attcagcatt ctgcttgtgc tttgaacggc atcacttgtc
    41461 atgttttctg cctgtttttg attttgttcc caagtatgga tactaaaaat aacggtagca
    41521 gtcatcgtta caccgatcat gataaccgcg tatttccgca acagacgatt tagtaaggtt
    41581 ccttttgaaa atagaatccg aaacttattc ataactttcc aactgtttat ctaattcttc
    41641 acgccaatgt gttgtcatcg taccattcca aaccgtcaaa agaccaatga caccaaacag
    41701 gatcaatcct ttgaattgcc aagtcacgcc taaaattata ccgctaccaa taattatttt
    41761 tagaaaagac gaaaagctgg aaaaaaccga aataaaactt agctttagca gattaggaac
    41821 agagatcgta tattcactat ctaaaatcat actgtattga taagtagcaa ataggcagag
    41881 caaggcaaaa agtaaaataa aatcaatagc taaaaaaatg agccctttga tttgaacaga
    41941 taaatataaa ttgtaactca ataaagcagt accagataaa aataaactaa atagcagatt
    42001 gcctcttaaa aaatttcttt tatatatatt ccagcctctt tttattgtga tttctttata
    42061 ctcgaatccg tacaaataaa atagttcatt gactgttttc catgccgcac ctaatccaaa
    42121 gatgatcccg ccggcaaatg tatatatcca gaaatacaag gttagtttta taatgaccca
    42181 gatccggata aataactctt ccaaaacctt ccctaacata tcttctcctc caaacattaa
    42241 gtttatactt tctcattata caaaaaaagg ttgggcaatc agcaccttga cctgattatt
    42301 agagaaacaa acggaaaaat agttcctcat attttgtcgt tttgtgagcg aataccgagg
    42361 gttagctgat tgaacaccgt ttaccaagag tttgtgaaat agccgcttag tttcgagtag
    42421 taagaaaaat tttgtgaata tggctttcca catttttaca tatatttagc ttaataccga
    42481 gaaactggct tttgaacacc gtttattcgg aacaagaggt tgtgacacgt cttttgtcac
    42541 aacccctttg tctttattca ttattattct tgtcggaact catcatattg tttttgcatt
    42601 tctttcaata ccttatcata gccagccttg tccaaagcgt ctttcaattt cggtaatgtt
    42661 tcatctggat caacagtccc tgtattcaat ccatctaaat attgattcat gacattagaa
    42721 atattactta attctgtttt gacactgtca gtgttgaagc tgaatcctaa aatcggtgaa
    42781 gtttctgcat cagcaatcga ttgatcacgt ttggcaatca tgtcatccgt aatagactct
    42841 tgtgtatata gaatcttgtt gtttcctgta ttccaagcag acatatgtgt atttggctga
    42901 taaccatcta gcaatttgat tttatcatct gaaccatcga ctttttccca tgcttctccc
    42961 tcgatccccc aaacaagccc attcaataat tctggatcac tgttaagcag ccctagaagt
    43021 tctactgatt tttctttatt ttttgaagta tttgatacga caaaatttgc catttgtgct
    43081 tgagctgtag attttagtgg aacagtaatt gcttttgaga caagttcttg ttttgctgca
    43141 tttgtcaaaa ttgtatcgcc ataatcatac ggtccttgtg tttctccacg cattagccaa
    43201 gtatttcctt ctagtggata atccttattg ctcgttgcag cgtcacttgg aatgagtcct
    43261 tgtttgtacc agctatgcat tgtacgtaac agtccgatat acgtttcatt atcgtattgg
    43321 ttgatgattt tcgaatcatc tccatccaga tcaatagcaa atggtaacgt attccctaaa
    43381 ggataatcaa agttcccttg gactttgaag ccttgtccaa tggcaaaagc tgccgtgttt
    43441 ggttcttttt catggaattc cttcaagact ttttctgcat cagcgtaaga ttggattcca
    43501 tcaattgaaa gatcgtattt atctagtaaa gctttgttaa aagtaagtac ttgttgagca
    43561 aagacatttc cattgactgg gaaagcatat aattttccat tgaccagatt tcctttaata
    43621 tatgcttcat ctaaatcatt ataagctttt tcagcgtact taggcgctaa ttcagtcaaa
    43681 tcagcaaagg ctcctttttg ggcattggaa acatagttgt tcgcaaaggc gatatcataa
    43741 ttttccccgg aagaaatgat gacgttcatt ttcttttcgt aatcgcccca gccaatgtaa
    43801 ttgatattga cttttacacc gatctctttt tcgattcgtt tgtttgctac ttccatcaat
    43861 tgatcgaaat tatctggttt atctccgatt tgatacatct gcaaagtgtc cgaattgcta
    43921 gcttctgcct ggtctttaga accagaacct ccgcatgctg ctaatgttcc caacaacaac
    43981 gctgaaacac ctgtaaaggc tagtttcttc cataacttca tttttcttcc tcctaatttt
    44041 atgatttata tttttgtttc tttattcttt tactccgccg attgttagac ctttgacaaa
    44101 atgcttctgg aaaaatggat agctgatcgc aataggcaac gtcgagatga ctacgatcgc
    44161 cattctggca gattctcctg gaactgaggc taatccgcct gtcaattggc ttcctgctcc
    44221 tgaattttgt gtcagatatt gaatattact ttggattttc atcaaaagat actgtagtgg
    44281 aactagctta tcatcttgga tgtatagtaa agcattgaac cagtcattcc agtaacccaa
    44341 tgcggcaaat aaactgattg tcgcaatacc tggaacagct aacggtaaaa cgatctgaac
    44401 aaatattcgc agttcgctag ctccatcgat ccgtgccgat tcaataatcg aatcagagac
    44461 cgaacgttta aagaatgtgc gcatcacaat aatattgaag ggactgacag ccattggcaa
    44521 gatcaatgcc caaatcgtat cttttaactg aagaagattt gtcataacaa gataattggc
    44581 caccatccct ggtgagaaca acatcgtaat caaacaaaaa acggtaaaaa aacgacggaa
    44641 tggaaagttt gaccgtgaaa tcgcataagc atataaagaa gtagccgtgc tattgatcag
    44701 tgtacctaaa acagtaacaa gtacagtgac gaaaagcgct tggaaaattt tatcctgcat
    44761 ctggtcgaac aagtacgtat aaccaaatat actgaacttt tctggccaaa aactgtaccc
    44821 gtgagtcgac aatatggact catcggtaaa agagatggcg ataacaaata taaatggcaa
    44881 aatacaggaa atagcaaaga gtgcaatcat tatattagag aaaaaattag ccgtcttatt
    44941 gaaagagcgg acttggactc tctccacttt cttttttttc atttttttcc tccttagaat
    45001 aatgcagaat cgctatcaaa acgtcgggcg atcgtatttg tgatcatcaa caagacaaag
    45061 ccgacaactg attggtaaag tcctgcagca gccgtcatac caaaatctcc tgtggatgtc
    45121 aggccattgt agatatacgt atccaaaact tgagtcacat catataatgc accggaattc
    45181 ctaggaatgt tataaaacag gccaaaatca gctcggaaaa tgtttcctac ggctaaaatc
    45241 gttaaaatcg tcattagtgg aataagttgt ggtatcgtca catgtttgat ctgctgccat
    45301 ttgctagctc catcaaccat agcagcttca taataagtcg gatcgattcc cataacagat
    45361 gcaaagtaaa taatgctgtt ataaccaatc cctttccatg taccaatgaa caccaagata
    45421 aacggccaat atttcggttc attataccaa ttgacagctt ctcctccatg tccagtgatc
    45481 cactgattga atattccttt gtcaggactt aaaaaagcgt aaacaaagta actgataatg
    45541 acccaagata gaaaataagg tagtaaggac atcgtttgat aaactttaac gagtcgttta
    45601 tttctcaact cgctcataat gattgcaaat acgactgaga tcagcagatt caaaaggata
    45661 aatgctacat tatataaaat tgtattttta gtgatgagaa atgcttgatc cgaagaaaat
    45721 aaaaatttga aattttccca acccacccaa ggactttccc tcaagctagc caagaaccca
    45781 tctgctgaaa tatgaaaatt tttgaatgct acgacattcg ccattacagg tatgtaaaag
    45841 aaaaaaatca tccaaagcat acccggtaca gccatcagga caagtgcttt ataacgccat
    45901 agattcataa aaaaatgatt gaaccccttt cgttttttca tctaaaaacc cctttcgatt
    45961 cattcgcaac gtaattatag cgctttcaat aatgagaata aataaacaaa gtatagggaa
    46021 aatgaaacaa agtataggag aggttgtgaa atcagcgttt tggcctgagt attagagaaa
    46081 aaaacgggaa aatagttcct catattttgc cgttttttga gctaataccg agggtcagct
    46141 gattgaacac cgtttatcag aggttgtgaa ttcagcgttt tggcctgagt attagggaga
    46201 tcgtgtcctt actatctaac tctgagtcac aaggaacaat ggggactgta acaaaagtct
    46261 tgtcacagtc ccttattccg aacaaacggt gttccagaag tagcttctac ggaaataagc
    46321 cgaaatttca caaaaaagcc atccgaaagt cagacggaca agtctgcttt tcagatggcg
    46381 ctacaactac tctgcttatt cttttagcta tccattcaat tatttttctc tcacttgttc
    46441 tagctcttct ttggtcatgg gtcgatattg ccctttattc aaatctttag gcagccaaaa
    46501 ttttcccata cggattcttt ttaaatataa gacttctttt cctactgctt tgaccattcg
    46561 cttaacttgg tgaaactttc cttcatgcaa aatcagacgg ataattgaag tttctgtctc
    46621 ttgatctact tgatcaattt ggagttttgc cggcaatgtc tgctcatcgc catcaataat
    46681 cagtccttct gcaaataaac ggatatcttc ttctgtcatt ataccgctaa cctcagctag
    46741 atattctttc tccacatgtt ttttaggtga tagtaactga tgggcaaaca ccccgtcatt
    46801 cgttaaaatc aagaggccct ctgtgtcttt atctaatcgg ccgactggaa aaagatcttc
    46861 ccgataatcc tggtcttcca ataaatcgat tacggtttga tcatgattat cctgagtagc
    46921 agaaatgact cctgcaggtt tatgcaaaat gtagtaaaaa tctttttgat acgtaatgat
    46981 ttctcctaaa taagtaaccg catcttcgaa ttcatttact tgcgctttat cgcttttcac
    47041 cacttgtcca ttgacttcga tcgttccttt tttgattaat cctttgactt ctttgcggct
    47101 gccaagtccc atatctgcta aaaacttatc taaacgcatg cgtttccccc atttcaaaag
    47161 agcatcaatc tagctcttct gattcactta ttttattttt aatttatgtc gtaaacgcgc
    47221 tattcctggt cctagtagtc tttctgccaa gcggattttc aaagctaaat aaccatacac
    47281 taaagcccct atacctgcta ctacaagaat caacaataga gactggaatt tgctatcttc
    47341 gtttaaaaaa gcaccaaaaa tcatctttgt gatccacgaa gccaaaagca taatcaaggt
    47401 aagaataaag atcagcaatg tcctgcgcca gacaaaactt ggtttaaagc gggctacttc
    47461 atggattctc tttaagatca aggtacaaga cacagcaaat ccgatcattg tcgccaataa
    47521 agggccgtat acttcaaata aacgaatggc tgggtattga agaaggagtt tcactagaaa
    47581 cccaataacc aaataattaa ttgccgcctt gttttcaaac attccttgca gcatgttgga
    47641 aactagcata tatagtccta ggaagagtcc tacaaaactt gcttggatca gtacattact
    47701 tcctagagaa tccggtgtat aaaataatgt atttagcgga taggcaagta acataacacc
    47761 aaatgtcgcc ggaaacataa aaaatgaaaa caactgtaaa tttccgcttg tcaattttgc
    47821 cagacctact cgatctttca acgtaacagc ttctgtaatc aacggtaacc cagtagacgc
    47881 gatcgatgtt gccaatgcaa taactaccat cgtcaactta tctggattgg cactaaaaat
    47941 cgaaaaaaga tccagtaact gtgcattgga atactcggtg gatgcagaca tgatcttcat
    48001 aaaagtgaac tgatcgacta atttgaagat cgttacccct gaacccacaa taataaacgg
    48061 aatcgcttct ttaacggtat ctaacaacaa ttccttcgtt gcaatattta ttttgttttc
    48121 gctgtagtga ataaacgccg atgtatacgc ttgatgtttc ttcaaaaaat acaaaaggac
    48181 aagaatactt gctagcatac cgataaatgc cgcgaaagtt gattgcgtga ccgccgtcac
    48241 atagtcacca tccatgactt tcatgatgat gaatgtagcc aatagcatat aaaaaatacg
    48301 tgccacctgt tctacaatct gcgacagcgc ataaggcatc atttcttgat tgccttgcaa
    48361 ataccctcgt atcacactca tacaaggaaa aaccaataca gcgatactca aagaacgcat
    48421 cgttggaatc agttcttctc cgccaccaga agcatgagct agccaaggag aggcgatgta
    48481 catgaacaaa gcaaacaaca ggcctaaccc gcccatcatc tgtaatgcac ggataaataa
    48541 tcgtcgtgaa gtgccatatt cattcaatga attatagcgt gcagtttgtt ttgcaatcgc
    48601 agcaggtatt cctgctgtag agatcagtag aaacaatgca tatatattgt atcccatatt
    48661 gaataatcca ttggcagcct tagcattttc gcccatccaa gcataccagg gaatgatata
    48721 gacagcgcct agcaatcttg aaatgatatt actggcggtc atccaagcag agcctcgtgc
    48781 cattttttct tgcggtgtta attgatctaa tgctggtttt ctttgattat ccatcggtca
    48841 gattccaact ttctacaaaa cattactatc attttaattg gtaaaacaga aactggcaat
    48901 cgattttata taacttttat aagaacaatt gtttttttga attcggtttc gtttttttgg
    48961 taaagtaaag aaatatacag ccttttatgg ctaacattta taggagatat caatgacaca
    49021 agaaataaaa aaactacccg ttatattttt aggtcttttc tttatcacag ttggattgaa
    49081 ttggttcttg ctccctcacg atatagcttc cgccggagtg ggcgccatcg gacatttagt
    49141 tgaaacggcc ttttctatcc aacgctcagt tactgtttgg agcatcaatc ttatgatgct
    49201 gcttctagcc gctgtcctat taggaaaatc agtatttttt aagactgtag cgggaagtct
    49261 gctttttcct gttgttttag agattgttcc aaaagtggaa atgatctcct cacatttctt
    49321 ttcactgatt tcaggaagtc ttttgttcag tcttggggtt tacacattgt acacagtcgg
    49381 ggcctcaaat ggcggtataa cgataccgcc gattattttc cacaaatttt ttcggcttcc
    49441 aatgccgcaa ggacttttac ttaccaatag tcttatcgtc tttttgaatt attatgtttt
    49501 tggattgttg gagacactat tcgttctcct atctattaca gtcagttcat tgtttatgaa
    49561 aatactcatc cgcttgtccc ctgtgtcaag aaaatttgaa taaagctgga ttttgtcata
    49621 gcggaaacaa acgatatatt aaaaagagtg tgctataata aaccaagaaa ttgaataaag
    49681 cgagggatca atcaatgagc ttctctttag aagacatccg tcatttacta ttaaaagaaa
    49741 atctattaaa agaatttgtt tcaacaagag gctggcatct tgatgtacca gaaaaagctg
    49801 aatttcttca gttaagttat gattcaagaa aagctgatgc ttctactttg tttttctgta
    49861 aaggaatgaa tttcaaagaa gaatatttgg attcagcaat cgaacagggt attcaatatt
    49921 atgtatcaga acaaccatac gaaaattcag cagtaggaat catcgtaacg gatatccgta
    49981 aagcaatggc gcttcttgct atggcttttt acgactatcc gcaaaataaa ttgaaagtga
    50041 tcggattcac tggaacaaaa ggtaaaacaa ctgctgcgta ctttacaaaa gcaatcttgg
    50101 atcacacaac aaataaaaaa acagcattgc tttctactat gaatacaacg ttagatggca
    50161 aaacatattt caaatcccat ttgacaacgc ctgagtcatt agatttatat cgtatgatgt
    50221 cagaagcagt tgaaaatggt atgactcatc tagtgatgga agtttcttca caagcttaca
    50281 aaacacaacg cgtatacggc ttgactttag atgtcggaat cttcttgaat atctcgcctg
    50341 accatatcag tccgatcgaa catccgacat ttgatgacta tttctattgc aagcgacaat
    50401 tgatcttgaa ttcaaaaaca gttgttttaa atcatgaaag tgactatttt gatttactta
    50461 gggaaacagc cgatctattc cagattccaa cgatcactta tggtcgttcg gaagaaagca
    50521 attatcaagt gatccgttca gataaaggta ctcacggttt tactttatct tctcatgaag
    50581 atcgcttagc tatctgcgat actgcttatg atattttgct ggctggagga ttcaaccaag
    50641 aaaatgcagc cagtgcgatc attgccgcag cactaacagg tgcctccagt caagatgcac
    50701 aagacggatt aaaagaagct cgtgtaccag gccgaatgga tcaattgatc caatccaatg
    50761 gagcgcatgt ctatgtggac tatgcacata attatctaag cttgaaaaca ttgctgaaat
    50821 ttgccaaaaa tgaacatcca gatggccgtg taattgttgt attaggcagc ccaggaaaca
    50881 aagcaatctc ccgtcgacat gattttggaa aagtgctatc agaaacagct gacatcgcct
    50941 ttttgacggc agatgaccca gcatttgaag atccgaaaaa aatcgcggaa gaaatcaatg
    51001 aagcaattac taatccagat ttgatcgttc attatgaaat ggatcgtcct gaagcgattc
    51061 gacgcgcttt agcagaaagc gctccgcaag attcagtcgt tattgcggga aaaggcgtgg
    51121 atccctatca aaaaatcaat ggtgtagatg aaccttatga aggggattat gcaatcgtga
    51181 agcggttgat tgaagaataa tggtatttat atactagtgg tttcccattt ctaagaaaaa
    51241 aagggactgt gattttttgt cacagttcct tttttcttag aaatcatttt aacttttcac
    51301 tagctaattc tgctgccttt tctctttctt catttaataa tttattatca tagaatttga
    51361 taaatgggaa ccagataatg aatgcgatga ttgcacaaat gactgctaac acagcagctt
    51421 tccaatcacc accactacca acaaatgctc cgatcccgac tggtgaaggc cacggcatct
    51481 gtgcaagcat cggtttgacg atttccagcc gaatggcaaa ataagcgagt gtagcagaag
    51541 ccatcggagc taagaaaaac ggaaccgcta aatagggatt gtagacgatt ggcatcccga
    51601 aaatgattgg ttcattgata ttgaataatc ctggtacaag tgaggctttt cctaacactt
    51661 tcagctgatc agatttcgcg aggaatgcaa taaagatgat caatcctaaa gtcgcacctg
    51721 atccaccaac ggttacataa gaattgttga attctcctgc caacggataa tttgcgcctt
    51781 gtgcgttagc tgccatatta gctaatacga tcggggtcaa gaaagaagtg atgatattcg
    51841 ctccatggat ccctacgatc cacaatgcat ggatcaagaa ataaatcacc atgacaccaa
    51901 gccatgtatt cgtcaactgc gtaacaaacc caaatgggat agcaatcatt ttgaagatat
    51961 ccgttcctag tgcaactaat aatccattga tgatcatcac cacaaacgca atgacaaatg
    52021 ttgggatcag agcagtgaaa gaacgagaaa ctcctggcgg aacaacatct ggcattttta
    52081 tgacccaatt tctcttgaca cacatacaat acaattcgac cgcaataatc gacataataa
    52141 tagctgtaaa gattcctgaa gttcctaaac gttcgacaaa agagcccatc ctaataccat
    52201 ttactacagt ttctgtctca ttgatagaag caatcaagct gattttacca tcagtcatga
    52261 tcaattcagg gatacacata aagaatgcaa aaacagatag taatgccccc gtgagcggat
    52321 taacatttaa tttttgttca tctcgttcaa ttgacgttaa ttcataagca aacacaatgg
    52381 caaagtaaat agataaaatc cccatcgtca ttgtattgac gatcatgtac aagtcactaa
    52441 ctttgaaaaa agttgcatta aaaaatcctt ctaaaaatgg gaacggtaat ggcaaaatat
    52501 ttaaaaccaa aaacatcgag cctacaatcg tgaaaggaat agaagccatc cccgctgcca
    52561 tgacagcccg aacgatttta agttgcgcaa ttttccccat aggtcccatc aggtatttct
    52621 gcaaaaaatc aaacattagt tattctcctt tcctaaatat aacgcttttt catattgttt
    52681 aatacggata tactgttggt cttggttgag tgaaattttc tttaaacgat actgtataaa
    52741 tgcactggca aaaataccgc ttacaacaag aatgaaaaca aataactgtc ctccattgtt
    52801 atttgccata aaaggataca agaatgtaaa tcctgaggta aacaacactg gaatcactaa
    52861 taaattaaag acactctgga acaaaaaata ccactttgtc catggaacgt tcgtttggtg
    52921 ttttcgataa agctttactt gttctcctac tgcaggcaaa atagctaaaa tcagaatcat
    52981 cggtaaacta cttcctaaac ttttagctga tagaagcaga atcatccatt gcatgttcat
    53041 gaaaaagaaa aaggcagtca ggtaacgtac gattagataa cgattgaaat acatgttttt
    53101 caaactaagt tgcttttttt ctaattcgat tttccttttt actgtatcct gcacaatgat
    53161 ccttcctttc tatttatttt tttgatacaa ataattcatt tcctgtgcaa cttccaataa
    53221 tgtcatcgtc gtcatcagat gatcttgtgc atggaccatg ataatttcca tttctatttt
    53281 tgtcccgctg gcatattctt tcagaagttg agtttgtgac tgatgcgcat gaagaatctc
    53341 ttcatttgct tgtcgcaact tctcttctac ttcttcaaac atctctttac gcatcgagcg
    53401 aaatgcttca tgtatcagtg tccgtgcatt tccgctatgg aaaatgatat caaaagaagt
    53461 cacttgtagt gtttcactgt ttattttttc agccatctgt tttcctcctt attcgatcag
    53521 tttgataaat ttactgctga aattctcaaa aataggttca gctaagattt cctgctgtac
    53581 ttttagctgg tcaactaacc taacgattgc tttagtcacg accgtaattc cttcattttc
    53641 gacataagaa ggcgaaacta aaaaaacaaa atgaatttct tgatattgat cccactgcat
    53701 cccagaagga atcaatgcaa cggctacctt tgtttcgatt ccaactggaa cagcgggatg
    53761 tgggactgcc actgtatcac tgaatatgat ttgtcccata ttttcacgtt gctggatctg
    53821 ctttcgcatt tctcttatat atccttcttc ttcatttatg ctcagctttt gcagcaaatc
    53881 atgaagaatt tcttcctttt tcggttcgta cgtataagtc ttgaaaaatt tttcagacaa
    53941 ctgttcggtg taaatctgct ttttttgctg tagagaaaat gctggtatcg gtctatctga
    54001 ggaatgatag ggtatagatt ctccaactac ctttcgtatt ttacgaacat catcttcatt
    54061 caaaaaaata ctgacatgta aaactggaat tttgaaaaac attgtcgaaa gatcaataga
    54121 agaaataatc aggtcgattc cttttaaagt tgtttcattg atctcataat agccttttac
    54181 acttaccact gtaatatttt taccgaattc actgactacg cgattcttta atagttgggc
    54241 actgccgtaa cccgttgcac agataatcaa tgcatgtagt ttatgcgcag ctctttcttt
    54301 ttccaatgcc gccatgagat gcaaagccaa ataggcccat tcatcttcat tgatggtata
    54361 gtttttcaaa gccggcatgt tgctgaaatg cctttttact gcgtcaaaga ctttgggatt
    54421 ttctttcttt atctcctcag tcaatgggtt ctcaatgcga atacctcggc tcaatcgaat
    54481 catcatcggt gacaaatgat cgagtagtcc attgaaaagc tggagatcct ctactaatga
    54541 aaaatgaaat tcctgagaca atcttttcag aactttcgct aattcctttg atagttcctg
    54601 atcattttga ttttctttgt gattcgactt agccatgaga tgtaatgtca aataagcaat
    54661 ttcttcttcg ggaaacgata cacctgcgat tacctcaata cgttgaacga tccgctgcgc
    54721 cacttgatac tctactcgct tagaaacttc ttgttcgatg cctaattcct tgatttcaaa
    54781 cccttctcgg agccgtttga tccccaaagc caagtgtaaa gtcagattct gtatgataaa
    54841 atccgaaact tttaacttag cttctcttgt ttcatcgaga atgataatga ctagctcttc
    54901 aaaactgatg tctgggaaaa aacggctttg ccctaaatat tctttcaatg aatttccata
    54961 atggtttcca aaaaaagtat ccatgataaa atgccgtcga tttctttctt ccccttcgat
    55021 ccatgtccct tgaccatgct tagaaacgat ttttagtgaa tatggaatca atcgctcctt
    55081 gatttcttgc atgtcctttg tcaaactgga acgactgata taaagctctt ctgccaaatc
    55141 atccataaaa agaatggcat cttccaaaag caattggttc aatatatact tttgtcgatc
    55201 ttcggactca taaaatcctt gcggttctct agcatatcca ggtactattt cttgccgact
    55261 caaaaacaag tcaaatgtca gtctttgtaa aatatgcagt tggtagccat aacctggttt
    55321 agcaatgatc ttacctccgt ttttttctac taactctttg atccgctgca agtaattacg
    55381 gattgtccga tcagataata acaattcaga agctaaacgt tgactggtga catactcctt
    55441 cttgtgatca atcaaatatc tcaacagcaa tttttccttc tgtttcatta tcatccactc
    55501 ctattccatc atatgttctc ttcgatcacc tctgctaact tctggatgcc tgtagggatt
    55561 gggacatacg cttggaaagg gatactaaca acaggctttc caacagattc tcctaatttt
    55621 ttgaatttat ccaaaaacat cgtcgtttgc gggctgatca gaaataaatc aaaatcacta
    55681 ttcttaatca tattatcgcc ttctgtagct gaaactgcat ctacgagtac ctcttctctt
    55741 ttttgcttaa agaaatccgt tgtctttgag gccatcatcg aggatgacat tcctgccgca
    55801 caaataatca atgctttttt cataaatcaa tcactccttt tatttttata aaccaagcat
    55861 atcttgtaag cgttttctat tcaaaatata tatttccgta gcattgcgga aaaaatgtgt
    55921 atcatatctt gaataataat ttctggcacc gtgatatact agtgatagaa ttttttcagg
    55981 aggggattta gtgagtatca cagtgaatat tttgtataca agtacaaatg gacaagccag
    56041 aaaatttgca gaagaaatgg tcgaaagaaa cattgtcaaa gcgattcgtg cagaagaagg
    56101 aaacgagaaa tatgactatt actttccact agaagatcca gaatctcttt tactgatcga
    56161 ccgttggaaa gatgaagaag caatcgaaaa gcatcacaaa tccgaaatga tggctcaaat
    56221 aaacgaactc cgtaaaaagt ataaattaaa aatgaaagtc gaacgtttca ctgatttacc
    56281 gtaaaaagat acacatggaa tgatagcaat ttatcatcca tgtgtatctt cactttttcc
    56341 ttatttttta ttcgatctca tctaatgatt caaaccgtgt ttttctctta tttttcggat
    56401 aagtatttca gtcaccccaa tatacatgat tcctaaacat accccaagga tattctcaaa
    56461 aatgcggatc gttactgctc ctggaacccc gaataaactg gcagtgattg ccaaagcacc
    56521 aaaagaatta aaaactgttt tatatctata ggtagaacaa acacctaaag ctagaccacc
    56581 taatataccg acccagttaa aaggaataaa ttggctgata ccaataaata aaacacatcc
    56641 aatcaatgag ccaatgattc ggtctactgc tcgttctttg aaaccaatcg acatcaatcc
    56701 atagctagat acaatagaag aaaatgcaaa ccctgcccac atcaatcgct gaaaagggac
    56761 atactctcct gcaacgatca aaagactaat gccaaatgca tagatgagca tccaaatttt
    56821 ttcctgcgaa tacatgcctt tcaaaaaaat ctctttaaac aagcttttgt ctttgttctt
    56881 ttctcgatgt tttctgtaaa ggagaactga aaaccaacaa aaaaacaaaa ataataagct
    56941 acttgtttgt gtaaagaaat tcttgttcaa cgaatcttta ggtaacgaat aaacaataaa
    57001 gagatatgaa aagccgtaca aagaagcatt ccccattttg ggatcactag cggttgccat
    57061 taatatgctg cttagtaaaa taaaatgaat caacatgccc ataactgacc atttgatcag
    57121 ctggacatac ggtgctacta atagtgagaa catgacgatt gctaaaccta tgatcgaatg
    57181 ggaaatctta taaccaaagt caacaaaacg aatactcatc aacatacaga ataaaaccac
    57241 agcgtatggt ttatgcttcg attcaaataa tgttgtaatt ataatgataa aacaaatggc
    57301 aaacaatacg atgaataatg atcgtaaaaa caatgaacaa atatacatgc acttttcttt
    57361 tttagaagct gcttctcgta ttttttgttt taaaataaac ggatctagtt gtagagactg
    57421 ataaaaatcc acctgttgtc gtcctttctt tttactttta ttttttacag tcatctatga
    57481 caggttgtaa atactatgga acatcatatg gcgttgtcat tttcttgtca actatttttc
    57541 ctattcatgt ttttataaaa aaacatatcg ttttcttgta tgattaaatc accacaaaat
    57601 aaacaactga gagaacgata tgctttatga atggttctat caaaaaaatt ctgagatcaa
    57661 tagacaaaaa tttgatgatt acagaggtct cttacgaaac cttacagaag aaaaaaacat
    57721 tgatcgttgc tgcagttctc ttccctgctc catgtgtctg tagaaattgt ggttctgctg
    57781 tggtagatgg aaataggaaa ttaatggtgg tgaaaaacaa gaagaaggaa accattgtcc
    57841 actttgaata atataatcat atgccaatgg ttatacgcct aaaaaagcag cgctatacct
    57901 gtaaaaactg tcgaagccat tggaacgctc aaagttattt tatccgtcca aggcactcga
    57961 tttcaaatca tgtcagacat aaaatcactt ctttactgac tgaaaaagtg tcgttatttt
    58021 ttatttcgaa aagttgttag gtatctttga caaccgttat tcgcacattg aaagagttga
    58081 gaagctattt accaaagtct tccaaaagaa ttctgtcttg agtgttgagg gttgtgaatt
    58141 tcgttctcac gtttccgttg aggataaact gagttttatt tccgcggatg gcgagacaga
    58201 aaaattaatc gagaaaattt acctacacaa aaaattcctc gattaacaaa ctatttcctt
    58261 agctgcacta atcctaaaga aatagaattc ttagttacag acatgaacgc cacctacttt
    58321 cagctcacca aacatgttct accaaatgcg aaattggtga ttgatcgatt acttggtttt
    58381 tccacgcctt tcaaggaggc gtaaccttta ttcacgagtt ggttgaagct ttccgagaca
    58441 aaagacccga cttgtttttc tccttattga caaagagcca ttaaaactag agaaaaaatt
    58501 acaactgatc gctgattatt tgtagaaaga aaatcaaagt attacccaat aaacttgagt
    58561 cattaggcaa aaagcactgc gaaactcaag aatgattttc gcagtgtttt tgtatatttt
    58621 ttattaacta gtattactac aaaggtttat ttttcacttc tcaacgcagc acaaaattgt
    58681 ctttacttat ttactggttg ggttcaacct tctctactcc gatactaata tttgtttgta
    58741 taccccttct aaaatcggta gtttccattc aattgatggg tactagttga ttttaaaaac
    58801 tatgcttatt caatttttta ttttagctca tatatttcgt ttctttctaa attttatact
    58861 gatgaaaaca agtagcacac ccaatattga caatataaac tggctaatga tggtttctcc
    58921 agtttttgga agatgcttat ttccactgct tgttggattg tttcctctta tatctgagct
    58981 atcagcaact tttctattct cttttgttaa aaagatcgcc acttcttgtt ctttttcgat
    59041 cttgaaagtt actggtgtcg catccaattc ataccccgtt ggcgcttgag tttctaccag
    59101 ctgatatgct cctggtgcta agccatctat cgccagtttt ccatctgctc ctgtggttag
    59161 acctgactgc agaacggttc cattggcatc ttgtaactca aaaacagctc cttgcaggac
    59221 ttctccgctt tggtcatcga tctttgtcaa cacgacaccg cctggtgtaa gtcgattttc
    59281 tttcgtcaat tctaccaccg ctgtctgact tctttcgatc tcaaactcga ttggtgtcgc
    59341 atccaattca taccccgttg gcgcttgggt ttctaccagc tgatacactc ctggtgctaa
    59401 gccgtcaatc gccagttttc catctgctcc tgtggttaga cctgactgca gaacggttcc
    59461 attggcatct tgtaactcaa aaacagctcc ttgcaggact tccccgcttt ggtcatcgat
    59521 ctttgtcaac acgacaccgc ctggtgtaag tcggtttgct ttcgtcaatt ctaccaccgc
    59581 tgtctgactt ctttcgatct caaactcgat cggtgtcgca tctaattcat accccgttgg
    59641 cgcttgagtt tctaccagct gatatg
//
LOCUS       DAIGUC010000011        57913 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.011, whole genome shotgun sequence.
ACCESSION   DAIGUC010000011 DAIGUC010000000
VERSION     DAIGUC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.011"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            270..836
                     /gene="amaP"
                     /locus_tag="NOB46_000671"
     CDS             270..836
                     /gene="amaP"
                     /locus_tag="NOB46_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI1057638.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            849..1037
                     /locus_tag="NOB46_000672"
     CDS             849..1037
                     /locus_tag="NOB46_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI1057639.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1050..1607
                     /locus_tag="NOB46_000673"
     CDS             1050..1607
                     /locus_tag="NOB46_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1057640.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1639..1881
                     /locus_tag="NOB46_000674"
     CDS             1639..1881
                     /locus_tag="NOB46_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1057641.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            2222..3436
                     /locus_tag="NOB46_000675"
     CDS             2222..3436
                     /locus_tag="NOB46_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HCI1057642.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            3467..4894
                     /locus_tag="NOB46_000676"
     CDS             3467..4894
                     /locus_tag="NOB46_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1057643.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            4917..5843
                     /gene="glsA"
                     /locus_tag="NOB46_000677"
     CDS             4917..5843
                     /gene="glsA"
                     /locus_tag="NOB46_000677"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCI1057644.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6051..7511
                     /locus_tag="NOB46_000678"
     CDS             6051..7511
                     /locus_tag="NOB46_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057645.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIVLSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7732..9495
                     /locus_tag="NOB46_000679"
     CDS             7732..9495
                     /locus_tag="NOB46_000679"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCI1057646.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            9579..10037
                     /locus_tag="NOB46_000680"
     CDS             9579..10037
                     /locus_tag="NOB46_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCI1057647.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10146..10829
                     /locus_tag="NOB46_000681"
     CDS             10146..10829
                     /locus_tag="NOB46_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI1057648.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            10976..11590
                     /locus_tag="NOB46_000682"
     CDS             10976..11590
                     /locus_tag="NOB46_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCI1057649.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11606..11812
                     /locus_tag="NOB46_000683"
     CDS             11606..11812
                     /locus_tag="NOB46_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057650.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            12351..12908
                     /locus_tag="NOB46_000684"
                     /pseudo
     CDS             12351..12908
                     /locus_tag="NOB46_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            12966..15005
                     /locus_tag="NOB46_000685"
     CDS             12966..15005
                     /locus_tag="NOB46_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HCI1057651.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15114..16265)
                     /locus_tag="NOB46_000686"
     CDS             complement(15114..16265)
                     /locus_tag="NOB46_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCI1057652.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(16419..16949)
                     /locus_tag="NOB46_000687"
     CDS             complement(16419..16949)
                     /locus_tag="NOB46_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI1057653.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(17048..17398)
                     /locus_tag="NOB46_000688"
     CDS             complement(17048..17398)
                     /locus_tag="NOB46_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HCI1057654.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVAFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(17555..19084)
                     /gene="ahpF"
                     /locus_tag="NOB46_000689"
     CDS             complement(17555..19084)
                     /gene="ahpF"
                     /locus_tag="NOB46_000689"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCI1057655.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(19094..19657)
                     /gene="ahpC"
                     /locus_tag="NOB46_000690"
     CDS             complement(19094..19657)
                     /gene="ahpC"
                     /locus_tag="NOB46_000690"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCI1057656.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(19801..20463)
                     /locus_tag="NOB46_000691"
     CDS             complement(19801..20463)
                     /locus_tag="NOB46_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1057657.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            20647..22293
                     /locus_tag="NOB46_000692"
     CDS             20647..22293
                     /locus_tag="NOB46_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCI1057658.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            22284..23366
                     /gene="uxuA"
                     /locus_tag="NOB46_000693"
     CDS             22284..23366
                     /gene="uxuA"
                     /locus_tag="NOB46_000693"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI1057659.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDIGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(23474..25027)
                     /locus_tag="NOB46_000694"
                     /pseudo
     CDS             complement(23474..25027)
                     /locus_tag="NOB46_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25175..26316
                     /locus_tag="NOB46_000695"
                     /pseudo
     CDS             25175..26316
                     /locus_tag="NOB46_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(26442..27521)
                     /locus_tag="NOB46_000696"
     CDS             complement(26442..27521)
                     /locus_tag="NOB46_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1057660.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(27624..28064)
                     /locus_tag="NOB46_000697"
     CDS             complement(27624..28064)
                     /locus_tag="NOB46_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1057661.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(28121..28531)
                     /locus_tag="NOB46_000698"
     CDS             complement(28121..28531)
                     /locus_tag="NOB46_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI1057662.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(28711..29145)
                     /locus_tag="NOB46_000699"
     CDS             complement(28711..29145)
                     /locus_tag="NOB46_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1057663.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(29245..30093)
                     /locus_tag="NOB46_000700"
     CDS             complement(29245..30093)
                     /locus_tag="NOB46_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1057664.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            30482..32248
                     /locus_tag="NOB46_000701"
     CDS             30482..32248
                     /locus_tag="NOB46_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCI1057665.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            32350..33609
                     /locus_tag="NOB46_000702"
     CDS             32350..33609
                     /locus_tag="NOB46_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1057666.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            33756..35057
                     /locus_tag="NOB46_000703"
     CDS             33756..35057
                     /locus_tag="NOB46_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1057667.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            35060..35911
                     /locus_tag="NOB46_000704"
     CDS             35060..35911
                     /locus_tag="NOB46_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1057668.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            35924..36739
                     /locus_tag="NOB46_000705"
     CDS             35924..36739
                     /locus_tag="NOB46_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HCI1057669.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            36890..38056
                     /locus_tag="NOB46_000706"
     CDS             36890..38056
                     /locus_tag="NOB46_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1057670.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            38286..38933
                     /locus_tag="NOB46_000707"
     CDS             38286..38933
                     /locus_tag="NOB46_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI1057671.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            39017..39961
                     /locus_tag="NOB46_000708"
     CDS             39017..39961
                     /locus_tag="NOB46_000708"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HCI1057672.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            40096..41547
                     /locus_tag="NOB46_000709"
     CDS             40096..41547
                     /locus_tag="NOB46_000709"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HCI1057673.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            41568..42404
                     /locus_tag="NOB46_000710"
     CDS             41568..42404
                     /locus_tag="NOB46_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI1057674.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            42404..43063
                     /locus_tag="NOB46_000711"
     CDS             42404..43063
                     /locus_tag="NOB46_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1057675.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            43189..43878
                     /locus_tag="NOB46_000712"
     CDS             43189..43878
                     /locus_tag="NOB46_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057676.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            43884..44840
                     /locus_tag="NOB46_000713"
     CDS             43884..44840
                     /locus_tag="NOB46_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HCI1057677.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            44884..45396
                     /locus_tag="NOB46_000714"
     CDS             44884..45396
                     /locus_tag="NOB46_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1057678.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(45652..46200)
                     /locus_tag="NOB46_000715"
     CDS             complement(45652..46200)
                     /locus_tag="NOB46_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1057679.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(46289..47470)
                     /locus_tag="NOB46_000716"
     CDS             complement(46289..47470)
                     /locus_tag="NOB46_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HCI1057680.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(47706..49214)
                     /locus_tag="NOB46_000717"
     CDS             complement(47706..49214)
                     /locus_tag="NOB46_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCI1057681.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            49373..49564
                     /locus_tag="NOB46_000718"
     CDS             49373..49564
                     /locus_tag="NOB46_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057682.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            49767..50684
                     /locus_tag="NOB46_000719"
     CDS             49767..50684
                     /locus_tag="NOB46_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HCI1057683.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            50677..51750
                     /locus_tag="NOB46_000720"
     CDS             50677..51750
                     /locus_tag="NOB46_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057684.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            51898..52416
                     /locus_tag="NOB46_000721"
     CDS             51898..52416
                     /locus_tag="NOB46_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057685.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            52397..52789
                     /locus_tag="NOB46_000722"
     CDS             52397..52789
                     /locus_tag="NOB46_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HCI1057686.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            52865..53800
                     /locus_tag="NOB46_000723"
     CDS             52865..53800
                     /locus_tag="NOB46_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HCI1057687.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            53933..54712
                     /locus_tag="NOB46_000724"
     CDS             53933..54712
                     /locus_tag="NOB46_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI1057688.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            54705..55022
                     /locus_tag="NOB46_000725"
     CDS             54705..55022
                     /locus_tag="NOB46_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI1057689.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            55266..56876
                     /locus_tag="NOB46_000726"
     CDS             55266..56876
                     /locus_tag="NOB46_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI1057690.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            57033..57881
                     /locus_tag="NOB46_000727"
     CDS             57033..57881
                     /locus_tag="NOB46_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1057691.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        19266 a        10229 c        11305 g        17113 t
ORIGIN      
        1 aaatagaatc ttgtaataat aactgagcat aatctttgca atttttaatc ttgaataata
       61 tcctttaagt atagccagca atcaaaagta aatagagaat aagtaagcaa ttgttatttc
      121 agtatcagac tggcaataaa acgccgttat gatccagcaa tgtttggtag cgctttattt
      181 actgatgcta tgctaactgt tcgctatcta tactgtgatt gtcggtagag ttatttacag
      241 ggtaaaaata agtttatagg aggtggaaaa tgaataaggg gttaaaaata atcggtgtta
      301 tcatgagttt actgctactt tcagtatttc tagcgattgc gttgatcaat gcgccgtata
      361 ttatgcctga acaattggaa cgatttcgct tctttacttt aacgaattac tacatgcaac
      421 aatatatttt ctgggcagct gtagtatttg ccgttcttgc tattatcatc ttgctagtcg
      481 ttcttttcta tccaaagtca agaggaactt tcgttatgaa acgggaagat ggcaaactaa
      541 caatcgacaa aaaagcgatc gaagggttgg tacgttccca tttacacgaa gaagagttca
      601 ttcattcacc taaagtacgg atacgttcaa cgaaaaatcg aatccatatc catgtcaacg
      661 gagacttgaa acgaacttct tcattagtag ggaaaacagg tgtattgatg caagatatcg
      721 aagaagaagt aactaaagta ctcggaacaa aagaaacggt caaagtggca gtcacataca
      781 gcggttatga agaacaagaa gatacaagag actacaagca ctctcgagtg gaataggagg
      841 gccaaataat gaaagaacta ttttcagcat acaagctccc tattatcttt gggggtcttg
      901 gactactgct agctgtttta tggttaacga ttggattttt caagacattg ttgatcataa
      961 tcatgacagc aattggcgca ggaatcggtt tttatttgaa acagtcagga atagttgatc
     1021 aattttttaa atcataggag gaaacaaaga tggaaaacaa aaacatgaat acaacaaatg
     1081 gatcagtttt ggcaaatgaa aaaggagaaa accgcatgat gaatggtgaa ttgacttatg
     1141 aagacaaagt catccaaaaa atcatcggtt atgcattgaa agatgtagat ggtctattga
     1201 cattagatgg cggatttttc tcaaatatgg ctgaaaaatt agtcaacaca gataacgtaa
     1261 cagcaggtat caatacagaa gtaggtaaga aacaagtagc tgtggatcta gatgtgatcg
     1321 tagaatacgg taaagacatc gaagatattt acaaccaaat caaagaattg atcagtactg
     1381 aagtaaacaa tatgacacat ttagatgtta tcgaagtgaa tgtgaatgtt gcagacatca
     1441 aaacacaaga agaataccaa aaagatcaag aaacagtaca agacaaagta acagaagcag
     1501 caaaatccac aggacaattt gcttcacgcc aaacagataa agcaaaatct gctgtaggca
     1561 aaggtgcaca aaaagtcaaa gaaaataacg aaccacgtgt acaataagaa gtaagaagtc
     1621 agttaggagg aatttaaaat gggatttatt tgggcattaa tcgtcggcgg tatcattgga
     1681 gcaattgcag gagcaatcac gaataaagga tcatcaatgg ggatcatcgc aaacatcatt
     1741 gctggtttag taggttcagc aattggacaa gctttactag gaacttgggg accaacaatt
     1801 gcaggaatgg ctatcattcc atcattgatc ggtgcaatca ttttagtatt agtcgtttca
     1861 ttctttgcac gtaaattata agcaaattga agaaaaactt atgttgaaat gaagaacaaa
     1921 tttgagaacc gtagcgacac tcgctgcggt tcttttttat atattttata tgaagtattc
     1981 tttattcctt atgaaaaaat atctttaaaa ataaaaaaag acgaaaataa acggttttct
     2041 ataaaaagaa gaccgtttat tttttgtctt tatttgtgtg aaaaacgaaa aagagcacaa
     2101 cacatcaagc ttttattaat tgtctgtctt ttataaatgc aagtattaat tcaaaaaaac
     2161 agaagaaaaa aacaactaca ccttctttta tactcgtaat cgtagaaagg aggcgaaaaa
     2221 aatgaataca ttacctatca atacaggaga tacagcattc atgattttat gtacagcaat
     2281 ggtttgcctg atgactcctg gtctagcttt tttttacggc ggattagcac ggaagaataa
     2341 tatactaacg atcatgtctc aatcttttct ctccgttggg ataacaacga ttatgtgggt
     2401 atttggtgga ttcggattgg cctttggacg ggatatcggc ggtgttattg gaaacccggc
     2461 agatttcttt ttgatgagac atgttacaag cttccccaac atgtttcatg gtgcaacgat
     2521 tccattttta atgttctttc tttaccaact gatgtttatc gtgattaccg ttcctttgat
     2581 gacaggagct tttgcaggga gattgaattt aaaaggctat attatacttg ttattttttg
     2641 gaatctgctg atttatttcc ctgtttgcca ctggatatgg ggtggcggat ttttggatca
     2701 gatgggattt agagatttcg ctggtggagc agtcatccac acgacagctg gattcggctc
     2761 tttagcatgt atcctcacac ttggtcaaag aaagattcct ttaggagaaa gaagtcagca
     2821 tagcagtctt atggcagctg ctatcggtac aggactgctt tggtttggct ggttcggttt
     2881 taattccggt ggtgcacttc gagcagatga acaagcagtc aatgcatttg gttcaacatt
     2941 catcgctctt gcatttgcga tgattacttg gctgatcatt gcaaaagtaa aaggaaatgg
     3001 ctttgatttt gtcgacgtac taacaggatc cgttgctgga ttggcagcca ttacgccttg
     3061 tgccggttat gtagaagcaa aaagtgccat gctgattggg atcattgcgg gtatcgtctg
     3121 tcatgctgct gttgattttc gtaaaaagaa acaatgggat gatgcacttg atgtgtgggg
     3181 tgttcatggc atgggcggat tcacaggtac gattctgata gggatctttg catctaacag
     3241 ccatttacta acgaatccaa gcagctggta cttcttaggg attcaagtga ttggtgtcat
     3301 cattactgcc gtgtatgcct atgtgctgac aacagtgatt ttaaaatcgg cgatgcactt
     3361 tacaacgatc actactacaa aagaagaaca agaagaagga ttggactttt tcttctttgg
     3421 caacaaactc aattgaaaca aattcaaata gaaaagagga agattcatgc aacaaagcaa
     3481 aacgaaaatt cctgcaaaaa aattaacgtt ctttggcttt ttggctatga ccatctcaat
     3541 ggtcgtttca ttatatgaat atcccacatt cgcgacctca ggcttcagct tagtattttt
     3601 cttgttatta ggcggtttgc tatggtttat ccctgtggca ttgtgcgcag cagagatggc
     3661 aacggtgaaa ggatgggaaa aaggcggtgt ctatacttgg gtcagtcgca cattgggaaa
     3721 acgattcggt tttgccgcaa tctttttcca atggtttgag ataacagttg gctacttgac
     3781 catgctgtat ttcttaactg gtgcattatc ctatgcaacg ggtattggtg ctatacaaaa
     3841 caataaatat ctgaaattgg caatcctatt gattattttc tgggctattt tactctcaca
     3901 gttaaaagga accaaataca cttcattgat tgctcggatc ggttttgtag ctggtatctt
     3961 gttgccagca ttagtcttgt ttggcttagg gatccattat gtcgcttcag gcgctccact
     4021 acaaacgata ctgtctatga aaacattgat tcctgatttt tcgaaattgc ctacgctggt
     4081 tgtttttgtt tcctttattt tagcatatat gggcgtagaa acatctgcca gtcatgcaaa
     4141 tgaaatggaa aaccctaaaa aggattatcc attagcaatg tttgtattgg ttattctggc
     4201 aatcatttta gatacttttg gcggattgac cgtcgctact acagtacctc aacatggttt
     4261 gtctcttaat acaggggtga ttcaatcgtt agaattccta ttaagacaca ttgatccaaa
     4321 tcttgcatgg attgcgaaaa ttcttgcgat tcttgtttgt ttaggtgtca tcggagaaat
     4381 tgcttcttgg gtaacctctc cttcaaaagc acttcacgta gcagcagaag aaggattact
     4441 tcctgaatat tttgcaaaag aaaacacaca cggtgttcct gctcatttga tgatcgcaaa
     4501 tgggatcgtt gcaacaatct gggcagccgt ctttacatta agcggcgggg ggaataatct
     4561 ttcatttctt gcagcgatgt cattgactgt tgtaatctac ctgatgttgt actttatgtt
     4621 tttcgcgggc tatttgaagc tggtttttaa agatgacagt cttgaaagag cctatcaggt
     4681 tccaggcgga aaagttgtaa aagtaatcgt tgcttgttta ggtcttttga cttcactttt
     4741 tgctttttgt atctcatttg ttccacctgc tagtatcgca gctggacagc atgggattta
     4801 tgaaacgatt ctgattgttt cttatcttat cgtcttagtt attccattta cgatctacgc
     4861 atgccgtcat aaattccagc atgcagaaaa ataaaaaatg aaagctggtt attcaaatgg
     4921 aagtaaaaga attagaacaa ttgattggaa aaaatttcca ctattatcaa acaggacaag
     4981 tggcggatta cattccagca ttagctgaag tggatcccaa acaattaggt atggcgattt
     5041 atgatttgga tacaaaacaa ctgattgagg gaggagacgc cgatgtgcgc tttgccatcg
     5101 aaagcatgtc aaaagttccc gtattgttat tagcaatcaa agacaacgga atagaaaaag
     5161 tctttcaaac aatcaacacg gaaccaaccg gttttgcctt caattctatc atgaatatgg
     5221 aaatcaatca tcgcaaacat ccaatgaatc cttttgttaa tgcaggagcg attgcaacaa
     5281 cctcgttgat tgccggtaaa gatgcagatg aaaaatttga gcgaatcttg tcatttatga
     5341 aagagatctg tgatgatcct aatatcacat tgaatgaaga aatctatcat tctgaatcaa
     5401 gaacaggtga tatcaatcgc tctcttgctt actatatgaa aggtaatcaa atgatcgaag
     5461 gagacgtacc ggagatactc gatgcttatt tcagacaatg ctccctcaat gtcaccgcta
     5521 caggcatagc aaaattagct gctgtgctgg caaataaagg aattgctcct tggaatggca
     5581 aacaaatcat tactgaagaa agtgctacaa tcgtcaaatc aattatgaca actgctggtt
     5641 tgtatgatga atcaggagag ttttccgtcc atgttggtgt acctgcaaaa agcggtgtag
     5701 gcggcgggtt gatggcagct gtgccaaatc gttacggcat aggtgtcttc agcccggcac
     5761 tagatccatt tggtaacagc gcagctggta tccaattgtt gaaagatgta gtcaaagaac
     5821 tagacgctga catctttgaa taaccattct tgaaagaggc tggggtaaaa gtccaaacgg
     5881 ctcaaagcta cctacaatga ggctgaaatt gtgagcttgt ttgacttttg tcccagtttc
     5941 tttttttatt ggtttttgaa agggcttttc taaataaaaa ggaaacaaaa atacgattta
     6001 cagatatgat taaataaaat cataagaaaa actggaggcg tgtatcagga atgctggaaa
     6061 attacatcga gcgaaatata tttagaaaag tgtatctgtg tgaacaatta tttgaattcc
     6121 aagaaataga catcgaacaa acagctattt ctctaagggt gactacacca acgatccttc
     6181 acgatctaga aagtctagcc gagtgtctag aatattgtat aaaagaacaa gtaagagaga
     6241 agcataagta taaactcgta ttcaaacatg gtattgttct ttctgagctc acacagtttc
     6301 tgtacggtca atcttatttt ttaaagtttt taagttatta ttttaatggt atattcacga
     6361 gtacagaact ggctgatctt gaatttattt ctttgagcaa agtatataca atcaaaaaaa
     6421 tcgtattgga tttttttaaa gaaaatgatt atttgaaaaa taaagaaatc attatcccag
     6481 aatttgactc gcggaacatc ttgctagctt tagtacgtta tgtcaattgg gaaggctatg
     6541 aaaataaaaa tccgtatgta gaagaagctt gtaacgagtt gattgattat gtagagactc
     6601 atttttttaa aagaagatat tcggaagatg aaaagtcctt tatcatacga ggaatagaga
     6661 tcgcaatcgg aagaaaggca tttccccttg gactgaaaga agaagataag aaaagcgcag
     6721 aaacgaagcc gttatttcaa ttagtctgtc aaggattgga agagcaaaaa ggaattctag
     6781 acttacaaga agaagatgtc tattatattt tttctttgtt caacagtaga aattatacca
     6841 atgagaacat ggagctgtta agaaaagatt tcgaagttgt ttataaaaat tttgttctca
     6901 atgacctatc actgaatgaa ttgattttac agattattag tatcgctgaa atcgacgatg
     6961 cagaaaattt tattttcaag caatcctttt tacaatttgt ccgtacgttg tgggcagatg
     7021 gacaagtatt tttaccggaa aggatctatc ttctatcaga aaaagaacaa cttctgtacg
     7081 gaaaaattgt agaaatattg gaagagtgga aaaagaaaaa tcaaatccaa ctaagatgga
     7141 atgaaaattt cattcgaaaa ttcgtcaaaa gtctttcttt gatcaacagt gaacaagcgg
     7201 ggagacagga aatagaaatt tttgttgttt cagaaagttc agtcaaacaa tttttttatc
     7261 gaacccaatt tcatttgtat gcggaagaag gcatcgctga aataaatcct attttatttc
     7321 gttcattaga agaattgcct gatgaatgtc tatgtgcgaa aaaaagagtg gttttgtgcg
     7381 atgctgctag ctatcaaaat ggattagaaa ctgaaaagac aaagatctat ccaatctcat
     7441 taaaaggtgc aaacatccat ttgtatcata ttgctcagga acttcaccta ttaaaaaaac
     7501 atatttcttg atgagacctt aattaggaga ccttctacaa agctttttaa ttgtctgtag
     7561 aaggttttta tttgagtcct gattcgtgcg aagatctact tatataacaa gctttctctg
     7621 aaattttttt aaaatgctat tgacttagag tcaactctaa gtagtagaat agataaagtg
     7681 taacaaatct attttcatta aaagaagata gtacggagga gagaatgtat tatgagtaca
     7741 gtattacatg tattggatgc aatcaatagc cccgcagatg tcaaaaaatt atctgttgag
     7801 gaaatgaaac agttggcaga agagatgcgc caaaaaatct tgcaaaagga cagcgatgta
     7861 ggtgggcacg ttggtccgaa tctaggtgta gtagaattaa cgattgcgtt tcattatgta
     7921 tttgattcac caaaggataa aatcgtttgg gatgtttccc atcagtctta tggtcataag
     7981 cttttaactg gtcgaaaaaa tggttttgaa aaaggacatt accgtgaagt gagcggatat
     8041 tccaaccaac atgaaagtaa acatgactat tttacagtgg ggcacacatc tacatctatc
     8101 agcttagcaa caggtttagc taaagcgaga gatctgaaga aagaatcagg aaatgtggta
     8161 gcatttatcg gtgacggctc cctaagtggt ggcttagctt ttgaaggatt gaacaatggt
     8221 ggtgttttac aatccaatct aatcgtatta gtaaacgata atgagatgtc tattgatgag
     8281 aatcatggca gtttatataa aaacttagct gagcttcgtc aaaccaacgg taaaagcagc
     8341 aataacctat ttaaagcaat gggatttgat tatcgttacg tggataatgg aaacgatctg
     8401 gaaacggtga tccgtttatt tgaagaagta aaagatattg atcatccgat tgtacttcac
     8461 gtccatacgg aaaaaggtcg cggttatcag ccggcaatcg ataataaaat gaaatatcat
     8521 tggcatgtac catttgatct gtccaccggg gaggcaaagc aagtaacttc tggagaaaca
     8581 tttaatatga tcatcatgga ttatttggat aagaaaatgc aaacaagtac agctcctatt
     8641 gccgcagtca atgcagcgat accaggcgcc tttggactga aaacattcca agaaaaacat
     8701 ccagatcatt attttgacgt ggggatcgct gaacagcact ctatcacttt cgcttctgct
     8761 ttggcttctc agggagtacg tccagtcgtc ttccaatcaa gtactttctt gcaacgggca
     8821 tatgatcaat tatcacatga tttagcgatc aacgagaatc cagtgattat tttagtcggt
     8881 ggcggaacga tctcagctag tgaccgaaca caccaaggaa catttgacat tccttactta
     8941 tcaagtatcc cgaacatcaa atatcttgct ccagcaacaa aagaggatat gatctctatg
     9001 ctagattggg cgttcgaaca aacagcgcag cctgtagcaa tccgaattcc tacacatggt
     9061 gtagaacatg gtacagctat cgcaaatgat tatagtattc cagcctatca aacagtaaat
     9121 aatggaggaa aagtagcaat tttagcttta ggcggttttc ttgaattagg aaaagaaaca
     9181 gtaaaagctt ttagaaaaaa aggaatcgaa gcaacgttga tcaatccagg aacgatcaca
     9241 gaaaatgacg tagaaacatt agataaatta aaagaaacac acgaattagt catcacatta
     9301 gaagatggta gtttgtcagg aggatttggc gaaaatatca gtcgttatta tggtgattct
     9361 tcaatgaacg tattaaattt tggtgcagag aaagaattca cggatagcgt tcctgtaggg
     9421 cagctttatg aacgttatca tttaacacca aaacaaatcg ttgaagatag tctgcgtgtc
     9481 ttgaatattc aataattcat tatgctcacc atccagataa ttgtttatac tagtatctgg
     9541 atggtttttt cattataaaa agcaaagggg tggatgttat gtatcagcaa gtagaagaat
     9601 atgtcaaaaa gttccaagaa aaatatccta gttatcaatc agaaaaatta ggtttctttt
     9661 catttgggga tacagaaaaa atggcagacg agttgagcga actagttgta aaaaagataa
     9721 agactggtac atcaagtggt tacgatctgt ataaacaaga gaatgagcct ttaccaaaag
     9781 ttggtcaatt agacgtggtc ctgaatggaa aaaatgaacc agtttgtatc atcaaaaata
     9841 taaatgtgac catcttgcct tttagtgaag tcacgaaaga gcatgcttgg aaagaaggag
     9901 aaggggatcg gacattagct tattggcgga aagtccatgc tgagtttttt aaacatgctt
     9961 ataaagaagc gttgaacata gaatttacag aagagaagct ggtcgtatac gaagaatttg
    10021 aagtaatttt cttttagtaa gaaaggtctg ctgaaagaaa tagctcatta ttgtctcctg
    10081 aatagaaaag ggttacattt ttatatgaag ctgtattttt atataacatt actggaggag
    10141 atattgtgga tacactggaa caaatcaaag gcggagtcgt cgtttcttgt caagctttgg
    10201 aaaacgagcc gctacacagt tcttttatta tggggagaat ggctttggct gcaaaagaag
    10261 gcggagcagt tggtattcga gcaaatacga cagaagatat caatgaaatc aagcgaatcg
    10321 ttgatttacc ggtaataggg attatcaaaa gagattacga tgggtcagaa gtgtttatta
    10381 ctgcgacaga aaaagaagtg gaagaacttt tggagacgca agcagaaatc attgcactgg
    10441 atgcaacttc tcgtaaacgt ccgacagaaa aaacaactgc tgaacttgtc caaatgattc
    10501 acgaacacgg tcggttagct atggcagata tttcgacttt tgaggaagcg cttcaagcgc
    10561 aagaagatgg ttttgatctt ttgtctacga ctttagcagg ctatacagaa tattcacgaa
    10621 agacgcagac acctgatttt gatttattga atcaaatcat agaacaagtc gatatcccag
    10681 taattatgga aggacatact gactctcctg aacaagtaga gaaagcatat gaattaggtg
    10741 ctttttcagt cgtagttgga tctattatca cccgtccgca attgatcact aaaagatatg
    10801 tcgaagccgc aagtaaagca aataactaaa aaacacgcac ggcacagatt cttgacaaaa
    10861 aagaaaaatt gatagatagt ttaaagcaga ttctaagaag atgaaaaaag cattactttt
    10921 cattttgtct tcaagatctg ctttttaacg aattttatag aaagaaggcg aaaccatgtt
    10981 tgaacggagt ccttcagaat tgacagaacg tgaaaattac aagttgctga ttggttcagt
    11041 catccctaga ccagtagcag tagtaacgac taaatcagca aaagatatag tgaatatcgc
    11101 acccttcagt tacttcaata tcgtcagttc gaatcgaccc atcttatcct tggcgatcca
    11161 gagaaaacaa gatgcagtaa aagacacagc aaagaatatt cttgagacaa gagaagctgt
    11221 tatccatatc cttgatgagg acaacgtaga agaagtaaat aaaacagcag ccaatctgcc
    11281 taatgaggaa agcgaactgt acctgactga cttgacttta actgattcag taatcatttc
    11341 agtaccagca ttgacagaag caaaagttcg ttttgaaaca tccttatatg aacatgtcga
    11401 gatacggaat aaaaataaag taacagctga tttatttttg ctagaagtac agaaatatca
    11461 tttaaatgaa acagtctatg atgataagac aggaaggatc gatccaagaa aattgaatgc
    11521 tgtaagccgt ttggcaggaa atgattatgc agcaatagga gaaattttca cgattgcacg
    11581 tcccgaataa aaaggagcac tagttatgtt aaaaataagc tataaaccat cgacagattc
    11641 aaaagaaatg aaaaaagaat atgaaacagt gaatgatttt ctgcaagggc agtacttaga
    11701 agttccgcca ttgcaagacc attttgtcgt tactactgtt actttagatg gtaaggaaat
    11761 agaaatgcca gatcaaacga ttagcggatt gtttaattac tttaacaaat aaatatttat
    11821 tccgaaaagt gaaaaaacat ataaaaaaac acataaaact aaaaaattat caaagaatcc
    11881 tggtgcaact gaaagaattt gcaacgggat tctttcaact tatttgttat ttttttctaa
    11941 aaaatattaa agattgttaa atttcactat ttcatttcaa attccattgc ctaatcatta
    12001 ggaaaagtct atcatgaact cgtaaataga atatagtaat aaccttgtta ggtgaggctc
    12061 ctatacaaac ataggctgtt gcccagaaac gtcgaaagtc gccaatgggt aaaacagaaa
    12121 ctgttggatt aaggcttttt ccaatagcta agaatgtttt ctttacgttg tatagtgcta
    12181 aaactcggac gatgagatga tgctaggtca gaattcttgt tcgaaaaggt ttctgacctt
    12241 ttctttatat ttttgtgact gacttatttg atgagacaaa ctcgctcctc acctgacaag
    12301 tggattgctg tgtgaggagg agatgcggtg aaaaaagatc gattggtgga ggtcgctcgg
    12361 attcacttct ggttgcacaa tacaaccaga aaacacaaca agcaaaactg atctctatca
    12421 tgagagattc atatgtcgat attccaggtt acggaatgaa taagataaat gcagcttact
    12481 cttatggggg agttgattta ttaaatcaaa cattaaagga aaatttcaaa tttgaagctc
    12541 cctattatgc aagtatcaca tttcaagatt ttatcgattg cgttaatgaa ctgtttcctg
    12601 gtggagtcaa gatcgatgca gaaaaatctc tagatttaga tggcgtatat ataaacaaag
    12661 gagagcaagt gatggatggt aatactttac tccagtatgc tcgatttcgg gaagacaaag
    12721 aaggagactt cgggaggatc agaaggcagc agcaagtgat caaagctatc tctcagcagc
    12781 tgaaagacgt aacttcaata ttcaagctac ccaaagcggt tgggaaatta cttggtagta
    12841 tccaaacgaa ccttccagaa agtgtgcttc tggattgtgg tatggatttc ctcaaagaca
    12901 tatgttagaa taaacaggta taaatagtga aataaaggaa tgacaagcaa gagaaggagg
    12961 aaaaaatgaa aagaagtgac aagcacggca aaaatcgaac aggcgcttat attgccggcg
    13021 cagtgatctt aatagcagct gcgggtggcg gttattttta ctaccagcac tatcaagaaa
    13081 cccaagcagt agaagctgga gaaaagacag ttgagcaatt tgtccaagct ttgaacaagg
    13141 gagattataa caaagctgca gaaatgacat caaaaaaggc ggcaaataaa agtgcattat
    13201 ctgaaaaaga gatcttagat aaataccaga atatatacgg tgctgctgat gtcaaaggac
    13261 ttcagatatc gaatctaaaa gtagataaaa aagacgattc tacttacagt ttttcatata
    13321 aagcaaagat gaatacctca ttaggtgaat tgaaagatct ttcttataaa ggaacattag
    13381 acagaaatga tggtcaaacc acgatcaact ggcaacccaa cttggttttt ccagaaatgg
    13441 aaggaaatga caaagtaagc ctgaccacac aagaagcagc aagagggaat attatagatc
    13501 gaaatggtga accattagca acaacaggca aactaaaaca attaggagtc gttccaagta
    13561 aacttggaga tggaggcgaa aaaacagcca atatcaaagc gattgcttcc tccttcgact
    13621 taacagaaga tgctatcaat caggcgattt cacaaagctg ggtacaaccc gattactttg
    13681 tcccattgaa aatcattgat ggagcaacgc cagaacttcc agctggagct accattcaag
    13741 aagtagacgg cagatattat cctttgggtg aagcagctgc tcagctgatt ggttacgtgg
    13801 gagatatcac agcagaagat attgataaga atccagaatt aagcagtaat ggaaaaatcg
    13861 gtcgctcagg tttggagatg gcttttgata aggatcttcg tgggacaaca ggtgggaaat
    13921 taagcattac agatgcagac ggtgtagaga aaaaagttct gatcgaacat gaagttcaaa
    13981 atggcaaaga tatcaaattg acaatcgatg cgaaggcaca aaaaatagct tttgacagtc
    14041 taggaggaaa agctgcatca actgttgcga caacgccaaa aaccggtgat cttcttgcgc
    14101 ttgctagctc tccaagctat gatccaaaca aaatgacaaa cgggatctca caagaagatt
    14161 acaaagctta tgaagaaaat cctgaacatc cattcatcag ccgatttgcg acaggttatg
    14221 ctcctggatc tacgtttaaa atgattacag cagcaatcgg tctcgacaac ggcactatcg
    14281 atccaaatga agtgttgacg atcaacgggc ttaaatggca aaaagacagt tcttggggat
    14341 cttttaaaac aacgcgtgtc agtagtgatg tatcacaagt agacttaaaa actgctttga
    14401 tctattccga taatatatat gcggcacaag aaacgttgaa aatgggtgag aaaaaatttc
    14461 gtacaggctt agataaattc atttttggtg aagaccttga tttgccaatt agtatgaatc
    14521 cagcacaaat ttctaatgaa gatagcttta actcagatat cttgctagct gatactggat
    14581 atggacaggg cgaacttcta attactccta tccagcaagc agcaatgtat tctgttttta
    14641 ccaacaatgg cacacttgtc tatcctaaat tgattgcaga taaagagaca aaagataaga
    14701 agaatgtcat cagcgaaaca gcagtacaaa cgatcgtgcc agatctgaga gaagttgtgc
    14761 aagatgtaaa tggtacagca cattctcttt ctgctttagg gattccgttg gcagcgaaaa
    14821 ctggtacagc ggaaatcaaa gaaaaacagg atgtaaaggg gcaagagaac agtttcttgt
    14881 ttgctttcaa tcttgataac caaggttata tgatggtcag catgttggaa aataaagaag
    14941 atgatgattc agcaaccaaa cgagcatcgg aactattgca atacctcaac caaaattatc
    15001 aataaaaaat tgctttttaa gtacagtaaa aggactgtgg cgttatcgtc acagtccttt
    15061 tttcaaataa acggttttca cgatgtctct ttcacaactt ctttttgatt tactcacact
    15121 tcataaactt tttttgtaaa atatttgaga acaagtggag aaataagtgt acttaataaa
    15181 atcacgataa ctaaaggtga atagtactgt ggttcgatca attgactttg ctgtccaatt
    15241 tgtaaaatga tcaaagccat ttctccacgc gaaatcatac cagcaccgac catcaatgaa
    15301 ctatgttgag aaaaaccggc aatctgagca ccaaaataac ctccaagcaa tttggtcaaa
    15361 atcgctacaa gcgtcaatat agaaataaag agtagttgtt cactaaagtc agaaaaatca
    15421 acttctaatc ctacactgac aaaaaatact ggtataaata ctgcatatcc taaagcctct
    15481 acattgtggt atacttcttc tttaaccttt gtctgactga cagctatccc agcaaaaaaa
    15541 gcaccaatga cagagctaag cccaacaaga tccgctacgt aagacattcc taaacaaata
    15601 actagcgata cgatgataat agaagaattt gcgtacactt tttctgcaaa tgaaagtagg
    15661 aaaggcgcaa tccatttgac taataagaaa ataaaaacaa aataaattag ctgttcaatc
    15721 aaaacaagcg gtaaagaagc attgctagaa gcttcccccg ttagaaaaga taggctgaaa
    15781 cttagaacta aaacgactaa aatgtcatct accacagaag cacccaaaat tgttgatcct
    15841 tcttttgtat tcactacgtt tagttctttt aatacttcta ctgaaatact gacagaagtt
    15901 gccgcaagaa taatcccaaa gaaaatcgct tcatttcccg aaacttggaa tgctttgcct
    15961 gtcaaccagc caaaaacaac cgggaagatg atcccaagca aagcaacgaa cataccaggt
    16021 cggaaatatt ttttcaaaag agataaatca ctttccagac cagctaaaaa cattaataag
    16081 atcacaccaa tctccgaaaa gtcatggact agaatatcag gtttgaccca attcaatcca
    16141 gcttggccta gcaaaacacc aacaagtaat tgtccaatca ctgctgggat acctaatctc
    16201 cgcgagatat gtgagccaat cgttgttgaa atcaatatca ggcataaaat accaataaat
    16261 tccattctca tcattccttt gtataaaata tagcccgaac ttagcataac atacattatt
    16321 gaaaaaatag gaaaatatac tcacaaaaaa accaacaatc caaaagattt ttttggattg
    16381 ttggttttta tacggtctat tttaataact aaaaatgatt aacgtatagt catttttctt
    16441 attctgatga aattgataat ctcctggatg cccatgaaaa tcaaaataaa gccgaatatt
    16501 tggaatagaa gcatcaaact tttgaatgga ttgaacaata agacgaatcc gccaatcaac
    16561 aacagaatac tactataaac actccaactt ttagcttttg tattcatgct gaagaacaac
    16621 tggaacaagc tgttgatgat aacagctaat ccaagaagaa tcggcaggat agaaacgatt
    16681 gcaggtgcaa aagcatagac gatcagagct aagatcagga aaaaaagacc actgaacaga
    16741 ccgatactcc aagaacctgt tttcctttta aaacggtaag cctcaaaaag attcaacaac
    16801 ccaagcaaaa caagataggc ggtgatcaga taaccgataa aatgaaaaac agcagaaggg
    16861 tttagcacaa tcgcaatccc agaaataata taaacagcag ctcttaataa ggcgtatttt
    16921 tgaatatttt gtttaatcgt ctcaaacata taagaaaacc tcctttgact tattttaacg
    16981 tgaactagtc attttaccaa attaaatgtt acaaaatgag cgaaggagaa gaatatctct
    17041 ggaaaaatca acttctgagg atcttttcca tttttttgcc ttttgctagc tcatcgatca
    17101 ttttatctaa ataacgaatt tctttcatca agttatcctc gatgtcttct actcgtacac
    17161 cacaaacaac acctgtaatc aaggaacgtg aaggattggg gacaggggct tccgcaaaaa
    17221 attgttcgaa agccacttgt ttttgtagtt gatattctag ttctgtttgg gaataacccg
    17281 tcagccaaca aatgatttca tctacttcct cttttatacg atcttttctc tccgcttttg
    17341 ctacatacat aggataaacg cttgcaaaac ttgtcgtaaa aatacgattt tgcgccataa
    17401 tcagtcacct ttcttttttt caaattattt actacttata gtatataaga aaaagagaag
    17461 aaaaagcgat tattcaaaaa aacaaaaagg attgtgacaa aattcttgtc accatccttt
    17521 tttccgctct ctgacttttt acaatcttca tagctcaagt gcgcatcaga taatcgaatg
    17581 ctcctaaagc tgcagtagct cctgaaccca ttgaaacaat gatttgtttg tatggactat
    17641 ctgtacaatc accagctgcg aaaacgccgg ggatattcgt tgcgccattt ttctcggtca
    17701 ctatttcatt tcttggattc atttcgatcg ttctatctag ccaatccgta ttagggagta
    17761 agccgactag aatgaatact cctgaaacag ctagtgtatg catctccatc gtacggcgat
    17821 cgatatagga gagagattct acctgattcg taccgctgat ttctttcgtc gctgcatgtt
    17881 tgataacagt gacattcgca agagagacta gtttatcctg taagatttga tctgctttta
    17941 attctggtaa gaattctaga acatatacat gttttgctaa cccagccaaa tcgattgctg
    18001 cttcaacacc agaattacca ccaccgataa cagcaatctc ttttccttta aataaagggc
    18061 cgtcacagtg tgggcaataa gcaattcctt tatttttaaa ctctttttcg cctggtacat
    18121 tgatagaacg ccagtgcgca cctgtcgcga tgatggcggt ttttgcttta agtgatatac
    18181 cgttagctaa gccaatatta ataaaatgtt gctctttatt taaggaaacg gcctgttgat
    18241 tcatcataat gtcgataggg taactacgca catgactttc tacttgctgc atcaattttg
    18301 gaccttctgt gtaagaggta ccaatcatat tttcaatccc tagtgtttca acgacttgtc
    18361 cgccgaaaga atcagcgaca agtcctgtac ggattccttt acgtgctgca tagatagctg
    18421 cactactagc tgctggtcca ccgccaatca ctaatacatc ataaggttct ttttcaaaca
    18481 actcttcttc aatcaaaggg ccagtgattt tttcaacaat ttgttcgatc gtcatgcgtc
    18541 cgctactaaa ttcttctcca tttaaaaaca cagttggcac tgccatgatt tttttatcat
    18601 cgatttcttt ttggaacatc ccaccttcaa tcatcgtatg agtaatattt ggatttaata
    18661 cagctaatat attcaatgcc tgtacaacgt cggggcaatt atgacaagtc aagctaacat
    18721 aactgtcaaa atgcaatgtt tgtgttattt ttttgatttt aagactcaaa gattcactga
    18781 ttttcggtgc ccgtccacta atttgtaaca tagccagtaa aaaagaggaa aattcatgac
    18841 cgagggggat accagcaaaa acgattccac tttctttgcc aactggattg atagaaaaac
    18901 taggtgtgcg catcgaatct cttttttccc aagagatttt aggagacatt tctgctattt
    18961 ccttcgtaaa ttcagctagt ttttgactat tttcactatt atccaaacta acagaaaaaa
    19021 caataggaga ttcaatcagt gctaaatatt gttcgagatt ttgtttagtt tctttgtcta
    19081 acatatccac cacctaaatc tttccaacaa gatcaaaact tggtttcaat gtttcgccac
    19141 tttctttcca ttttgccgga caaacttcac ctgggtgggt acgtacatat tgagcagcgc
    19201 gaatcttatc aatcagtgca ctagcgtcac gaccgattcc atctgcattg atttccatag
    19261 cttgaacgat tccgtctgga tcaataataa atgttcctcg ctgagctaat ccttgctctt
    19321 catccaaaac atcaaaaata cgagaaatct gatgagacgg atcaccgatc atcacgtatt
    19381 cgattttacc gatagcatct gatgtatcat gccatgcttt gtgagtaaag tgggtatcgg
    19441 tagagcaaga aaagacttca acacctaaag atttcaatgt actgtattgt tcttgtaagt
    19501 cttctaattc agtaggacaa acaaaagtaa aatcagctgg atagaagcaa agaatactcc
    19561 agttccccat aagatctttt tcactgactt ctaaaaattc tccttgatga taagcatgtg
    19621 cattaaattc ttcgattttt ttcccaatca atgacatagt aaaacctcca ataataatta
    19681 tttatttata attattgtaa tttagttgga gttgcaaagt caatggatat tttgttattt
    19741 aataaagatt actcaaaaac gaaggttaat tataaaaata gaagaggtcg caagaaaatg
    19801 ctactgctgg aaatactcgg gataacgttg agtaacagtt tcctgttctt tcagcatcat
    19861 gtgtaagtgc aatcccgttt gaaatcgagc ttcttctggt tttttatcaa ctaaagcctt
    19921 gagtaaatca taatgttgtt ccatgatcgt ttcccatgga agcccctgaa tggtcactcg
    19981 taaccagcgg aaacgttcta aatgggtatt atggtcatct aaccagttcc aaacttcttt
    20041 tcttcctgca atttcgaaac aagcttcatg aaataaatta tctgcacgga aaaaagcgcg
    20101 ttcgtcattt attttgactg ctttttcttg ttcttctaaa atcgtttcta gcactattcg
    20161 tgtttgtgtg tccaatttgg aacaacattc aatcatgatt tgctcttcca actgttctcg
    20221 gacaaagcga gcattttctg cagaaacaag attaattttg gaaacatacg taccactttg
    20281 aggtatcgta tacacgagtt cttgctgacg tagttgaatc aatgcttcgc gaatgggagt
    20341 ccggccgata gcaagatgtt cctccagtgc cttttcagat attttccttc caggttctaa
    20401 gtcagcatag ataatttgtt tacgaatcgc ttgataagct tgtgattgca agctgctttt
    20461 catctttatt cctccaaaat catttctatg aacgtagtat aacagaagag gtctgaaaaa
    20521 caatctggta tgtcacatta actagtaaat ttgtataaat agtaaaattt tggttgacat
    20581 agcgattttt attgcataaa attcacttga atacaaaaac taatatgtta gtttaggagg
    20641 ggaaaaatga ttgatttaaa caactggagg aactttatcc ctgaattatc tcaaaaagaa
    20701 gtagaaatac ctcattttga ccgtgcatca ttaagagaaa atggacaaaa aaatcctgtc
    20761 tggatccatt tcggtggcgg aaatctttat cgaggatttc atgcagaaat cgctcaacgt
    20821 ttagcggatc taggcgaatt gtccactggt gtcattgttt gtgaaacatt cgatgaagaa
    20881 ataattgaaa gggcttacca agattttgat gatttgattc ttgaagtggt catgccaagc
    20941 agtggagagt tcgtcaaacg tatattagct gcgacagctg acagtctgta ttgtcatcca
    21001 gattgttctg aacactttga taagatgatt cgacactttg aaaatcctag tttacaatta
    21061 gttacttttg ctattactga aaaaggttat cgattgaaag atacaaataa taaatatata
    21121 ggaccgattg cagtcgatat aaaaaatggt ccaaagaagc catcacatac aatgagtatt
    21181 cttgctgtgc tactttataa acgtttttta tctggagctt ggccgattgc acttgtctct
    21241 acagataatt tttcacaaaa cggtagtcaa ttacgtactt ctttgctaac gatcgcaaaa
    21301 gaatggcaaa aggaaggtta tgtacaaaat acatttatcc aatacttatc gaatgaagaa
    21361 attgttgcgt ttccatggac gatgattgat cgtatcaccc cgaatccttc cttgtcagtt
    21421 agcaaaatgt tggcaaaaga gggcttttca aatatgtcga ttttccaaac cgcaaaagga
    21481 aataatattg ctccatttgt caatacagag gacatccatt atttaatcat ggaagatcat
    21541 tttcccaatg gacgtccgaa attcgaaaaa gctggggtat tcttgactga tcgtgcaacg
    21601 gtagataaag cagatacgat gaaggtgacg acttgcctta atcctttgca tacgtcttta
    21661 gctattatgg gttgtttact ggggtatagg agcatagctg aggagatgaa agatccagat
    21721 ttatcgctgc tagtttctga aatcgggtac aatgaaggcc tcccagttgt ggagtctcca
    21781 ggtatcattg atccaaagat ctttctggaa gaagtaatta ctgtgcgctt ttctaatcca
    21841 aatattccta atatgcctca gcgaatcgcc acggatacct ctcaaaaggt ggcgattcgt
    21901 tatggtgaga cgattaaaaa atatatggaa atagaagtta aagacccgca gacacttgta
    21961 ttcataccat tgactctcgc tgcttggctt cgatacctta ttggcattga tgatcaagga
    22021 aaaccattca tcccgagtcc agacccacta ttgacagacc ttcagcataa gctttccgat
    22081 attcaactgg gtacgcaaga tacatcacat attcatgaga aaatggctcc tattttgtca
    22141 aataaagaaa tttttggtgt agatctttac caagcagagc ttggcagaaa aatagaagaa
    22201 atgttcatca agatggtagc aggaccaaat gccgtacgaa aaacattaca ggattactta
    22261 caagaacatg gaggaaattt atcatggaaa tgacttttag atggtacgga tcacaggaag
    22321 aaaagattac cttagatgaa atcagacaga ttcctgcggt caaagggatt gtaggcacat
    22381 tgatggatat accagtagga gaggtatggc ctagggagag gatcaaagaa ctaaaagaag
    22441 aaattgagtc tcgtgggtta acactaaaag taattgaaag cgtcaatgtg catgatgcca
    22501 ttaaaattgg attaccttcc cgtgagcagt atatcgaaaa ctataagcag acaatccgaa
    22561 acttggcaga atatggaata gaagtcatct gctataattt tatgcctgta tttgactggg
    22621 tgaaatctga ccttgactac cgcttagaag acggctcatc cacgttagct tttatatctg
    22681 atgatattcc agatgatcca agagaaatcg tcgcgcgcat cgaacattcc agcaatgaat
    22741 ttggattgcc gggatgggaa cctgagcgct tagctcctat caaatccttg cttgaagcct
    22801 atgcatcagt agacgaagaa aaacttcgag aaaattttgc ctattttctc caatcaatca
    22861 tcccaacatg tgaagaggta ggggtcaaaa tggctgtaca tccagatgat ccgccatact
    22921 cgatttttgg attagctcga atcgtaaaga atcgagaaga tttagattgg ttgtgtcgca
    22981 tagtagacag cccttataac ggaatcactc tttgtacagg gagtattgca gaagatccag
    23041 aaaatgatgt atatgggatt ttagcagaat tttgccaaag agatcgaatc ccatttgcac
    23101 atgttcgaaa tattaaattt ttagctaatc gagatttcta tgaggcacca cataaatccg
    23161 aatacggttc attagacatg taccgcatac taaaaacaat gtatgacatc ggatttaacg
    23221 gatacatccg tcctgatcat ggaagaatga tctggaatga gacaggaaga ccaggatacg
    23281 gcttatatga tcgagcatta ggtgctgttt atctaaatgg attatgggaa gcaatcgaaa
    23341 aaggaaacaa aagtaaagat aattagtgaa aaaaactgta attttattat gtaaataaga
    23401 aggatgttca aattcttgat acataaatcc ggaggttgtt aataagcatt cggatttatg
    23461 tatcttattt ggtctaggaa gtaacttgat tttctttttt cgattgatcc atgagtgctt
    23521 cttcttttaa ttcaaagata tattctgaga tcctcataat cacttttttc cagtcttctg
    23581 gtgtgatgat tccttttaaa atatagattt ttttgatatg agaaggcaat tgtttcaaag
    23641 ggcagtcgct gataacgatg ttgcagttct ccataaaatc attttgtatt ttgatcgatt
    23701 catttgaaaa aatttgttct atcttaacga tcagatcttt actgatataa aaatcacgcg
    23761 tatagttcac accaatcaca attcgcggct gttttttgta gcgatcatac aaatgtacta
    23821 ggtcttcaac catccattgc acattttcct tttctaaaat aactggtaac aagtgttgat
    23881 tttgttctct gaaatccata taaaattgtt caatggcggt ttggacttct ttcaatacgc
    23941 tatgttcttg ataaagcatg aaagtaggaa ggggcgtatt tggttgattg aagttaagaa
    24001 atccattata aagtttattt cgtgcgaatg ccaatgagta aagaatcttt tctttttcag
    24061 gtataaacaa atcaaataca gtacaaaggg actccaccat ttctcttgaa taaagaacat
    24121 gaggaacgtt tgcttttttt aaaagtttgt attgctccaa gcttgtttct tccgattcga
    24181 ttttcgtgat agaaagtcga gctaaaatat tcactaagat gcgttgttcg cgacaaattg
    24241 gcagattagg tcgcaaaata tctacagaga gatcaataaa aaagtcaata tattcatact
    24301 ctgtgaattc tttttgtacg tctttcacag aagttgcagg aaaattctct ttacatattt
    24361 ttaatagaaa atataattta tctatcatac cgctatttag tcggtcaagt acttcttttt
    24421 taaaaaaagt attcatcata aaagccacta cttgcggatc ttcatcataa aattctgtag
    24481 cagtacttga aaagatgttc caataaatat ctaatgctgc atattgaatt tgtacctctt
    24541 ttccagaaaa agactttctg ccattattag aaaaggagat agacaaaccg tactatgcta
    24601 aaaatgcatt aatctttttc attttcgtat acaaataaga ggcactatag tttgtttgct
    24661 gactgaaact gataatcgaa tttgtctgac agctgaacaa agaagtcaag atctgataac
    24721 tgactgattc gttgcagtat cttccaaata gacgataata gcagtaagcc ggatcaattc
    24781 cttcaaaatt caactttaaa aaaggttttt gcttatcaat atgcagttct gttagattga
    24841 gacgctcaaa gtcttgttct aattctttga tgtatagtaa aaaatttgat tcagacatat
    24901 ggaaatgatc tgctaaatat tgtgtagtaa taaagaaacg atgttcagat aggaaaagaa
    24961 aaatatctaa ttttgtattg ctttttttct tcaagataaa cgttttaatc gcttcttgag
    25021 tttgcatgaa agaggctcct ttttacttaa attgttaaaa cttgaaaata ttactgtttt
    25081 tttcataaat ttagacaaaa aaacagtaaa catataggta gaatctctac tatcttattt
    25141 cttgcataca aaaaaatcaa ggagtgagag agttatgaga tattcaacca tcttaatatc
    25201 aacatttgca gccttaagct tatcgcttac tataaatcag acagtccaca cagaggagac
    25261 agaaacagcc aaatggacag aaaccaagtg ggccaacgtc aatcgaatta cctttcagga
    25321 tgaattttca tccttcaatt caggagtcgc aaaattaaga aaaggacaaa cagcgaccat
    25381 caaagcaaaa attgactatt cgggagactt agcacctata ctacaatcag ctgttacatt
    25441 tgagaatgtt gatcccactt tgtcgattgg ctatgacgag aacactttga ctatccaaca
    25501 caagcaagcg atatttacct tcaccgttac attaaatcag gacttgttaa aaccagcgct
    25561 ttttactgtc aaggtatcag atggactacc gaacgatcat catttaacgc cgtatagtca
    25621 gcggcagaca attgagcaag attcagccat cgactcagga ggagatcttg ttgaagaacc
    25681 aacagataaa ccagaaaatg aaaataagcc agaagtaccg cctacagaaa atccagacgg
    25741 agaacagaaa ccggaaatag aacctggaga agaacccgat acagaaactc aaccagagcc
    25801 agacaataaa tcaaaacctg aaataacccc tggagaaaaa ccagatgtaa ctccagaacc
    25861 agatacggat tctggaaacc aaacagtacc ggaaacaaat ccagacacag ataatgaaac
    25921 tgaaaatcca gaaaaaccag aggtagatcc agaagaaaaa ccagatgtga ctccagaacc
    25981 agatacggac gcaagagacc aaggaatacc agaaaaaata aacaaaaaaa caattcaaga
    26041 ggatggaaaa aaagagagta aaaaatcaaa tctagcaatt ctaaaaataa atgaagagca
    26101 gctgaataaa aaatcacgaa tatttgatag cgcccaatca gctgaaacct taaaaagtag
    26161 caaggataca acctttgctg tcctgaaacg aaaaataaac agctaccaaa atccggagag
    26221 tcacaaaaca aagttatact gtggagcgga atcattctat taagtatagc aacaatgctt
    26281 tctgcaaaaa gatttaaaca aaacagatct ctctaacatt tgaataatgt ctgtgaacgc
    26341 atttttcaaa taaaaagaaa tatccagaaa atgaccccaa aataccagat tgaaatctga
    26401 tatttggggt cgttcatact ttatctttct tcatatttat tttaagggat atctgtttct
    26461 tttggaagat ggttcgggat ctttttcact ttcaatacat ctaaaaagaa ggtaaagatc
    26521 ggaatgccga caatcaagcc ccaaacgcca aagaaccgtt cgctaacaag taagaccaca
    26581 aatgtataaa aaatcggcag ttctgttttg ctggacatca acttcggatt cagcacataa
    26641 gactcaatta gatggacaat caaaatcgta atcaggatat aaacaacatc tcggatgcct
    26701 ccttgggaat aagctatgaa agatagagga atacaagaaa tgataacacc tgctactggg
    26761 atcagactta aaatgaaaat catgatcgct aaactcagca gctgatgaaa gccaaataca
    26821 gccaaggcga ttgtagtgag caacgtattt aaaagagcga caacaaattg agcttctaat
    26881 accaaaccaa atgtattgac aaacttatcg gcaaaatagt aaatatcttg aaagaaccaa
    26941 gaaaattcac tttttaaaaa caatcttgag aatacaattg tttttttctt ttcaatcata
    27001 aaaaagaaac ttaagatgaa tgacatagca aacgccactg ccatttttcc tatatcctgt
    27061 aaatagccaa gcgcaatcga agcgccattt tgaagctgtt caaaaaaatc gtttcgctca
    27121 atataagtat ggatatattg taaaacagga tctgcatctt ttggctgatg ctcgtaaaaa
    27181 ttaataacgg actggatcat gtcaaatgtt tgatgaataa gcatcgggat atactttgtg
    27241 aatgccagat agataaggta aacgatcagt gtataaatca tgatagctaa aacacctgta
    27301 gggattcgga caaatcgctg aatgatttga acaagatgaa tcatcaaata agtaaagata
    27361 aatgtgagca aaatggttgt aatcatactt ctaactaaga aaagaacaaa aacgacaaat
    27421 aataaaacag tgagacggcg tattttttca ttcgccaaaa aacgctgata aacggtcaaa
    27481 tcgacaacct ccaaataaca aaaaataaac acgttattca ttatatgatg gaatatgaaa
    27541 ataagaaaga gcaaaaagaa aaaccgctaa atgacgttat cttatgagtt ggttttcctc
    27601 ataaaatcgt tcatctagca gtttcagccc tttttctggt cttgatgaaa attatctagc
    27661 atttttcggg tcagatgttg cagtgtatcc aattcttcct gttcaagtgg aagataagac
    27721 ttgatctttt gtggaatacc ttctgcttgt ttttgcaacg cagcaccttg agcagtcagc
    27781 gtaacattta cgattctttc atcacccgtt tcacgctgac gattaatata atttttttct
    27841 gctaactttt ttagtaaggg agtcagcgta ccagaatcca gacacaaatc atttcctagc
    27901 tctttcactg aagtcttttt cttttcccat aaaactaaca tcacaagata ctgggtatag
    27961 gtaagattca gcggcttgag gaggggagtg tagtgtctaa tgatttcttt agaggcggca
    28021 tataaaggaa aacatacttg attaactaaa tatagatctt ccatttttcc acctccgctg
    28081 ttttactata gtgtatcata gcggatttac acaaaaaagt ctattcacta actgctttca
    28141 gagtaacttc tatatttcca gctgtagctt ttgaatacgg acacacttta tgcgctgcct
    28201 ctaataattc ttgcgtttct tccagagaaa gaccttcgat agatccttca atctctacac
    28261 ctaagacaaa gctcgtttca ctttctgaat aaagggaaac ttgtgcactg acagtagaag
    28321 ccccagagat atttttttgc tgtttgatca attctaatgc actgttaaaa catgcactga
    28381 aaccagctgc aaacaattgt tcagggttgg ttgcattttc gacgcgttta ccaggagctg
    28441 caatattcaa ttcgaatgta cgatcgggat tatgcacttc tccagagcgt ccgcctgtgt
    28501 tgatcatttt cgtagaatac atttttttca taaagttacc acctttaatt atattttata
    28561 caattgaatt ttacacaata taattgtgga aagcaaagaa atggattggc ataagataaa
    28621 taagagaaag cacatgaaac agacgcgctt tctcgaatag caaacatata caaaaaatat
    28681 cagagacaaa aaataatctc atcataaaca ttacatatat ttctcaaaaa gttgttttct
    28741 ttcttcaaaa attacttcac gatggacctg atgaagcatc cataaataac caaaaggatc
    28801 tctgaacatt gagttagtca caccaaagtc catcatttct gtcatttctt gaatctctac
    28861 acagccattt cgtaatgctt tattatgtgt gtcctcgata tcagagacga tgatattgaa
    28921 ccagatcgta tttggatgtt cagcagtagg agcagtcaaa ccaagagacg tgttttcatc
    28981 cagcatatgg aatctcgtac catacaaggt aaaaatgact tcattattgc ctctagggta
    29041 atctgttgcc tcaatcagtt gtatttcatc aaagattgtt tgatacagtt ctagtgcttt
    29101 caaactatca tttaatacaa aatcgatttc cgttccttta tgcataaaga tctcctctcc
    29161 ttttcagtcg aacagttact agattctttt attataccag ctaaagaaaa cgcattcaaa
    29221 aaaatagcgg atttacttac caactcattc gattggatga taagtaaatc cgcgtcccat
    29281 tacttctgct acgctgctga caatgacaaa ggcacttgga tcgatttctt ctatcaatgg
    29341 tttcattcgg gaaaattcat gatcagtcac aacgatcaat aaaacctctt ttgactttcg
    29401 attatacccg ccttttgcct ctagcagggt aaggccacgt ccaatctcag cacttaagcg
    29461 aaggcggatg tcttccaaat aatgttcact catgaccata acagatttct ttcgattgat
    29521 acctgtttcg atataagtca tgacaattga agtgattgca atagataaaa tagcataaag
    29581 aaactcttct attccaaaaa taaacagatt aagagaaaca acgaatgcgt ctgtaaaaaa
    29641 taagccaatc gaagtattca agtggaaata ttttttaaaa atgaggggag ggatcgtcgt
    29701 accgccgcta gaagagttgt ttttatataa aatcgcaact cctaaagcaa aaatcgcact
    29761 tccaaaaatg acagacaaca accgatctga agtaatcatt gtttctggaa ctattgcaat
    29821 gattaaagga aaaaccaagc ttccgaaaag tactttaaaa aagggttttt tacctaaaaa
    29881 tagaagagct agtaccaaca taacgatatt caacactaaa ataactatag ctcggtcaaa
    29941 gcctaaagca gcttccagta atattcctag accgctgaca cctccagcag caatatgatg
    30001 aggccctaaa aacatattga tagcgactcc taatatgaag agggcaaaaa taatcttaat
    30061 gtatgtccat ataaattgtc tcgtttcttt catttattca cttccttaat tcattaataa
    30121 tactcttatc ttattataac ttacttttca ccttaagtta actttaatta ataaaaaaat
    30181 taggctagtc taaattatta tgtttcattc ttctagaata tacttctacg ccaaaaactg
    30241 ttaaaaaact tttactttag aaaattggag aaattgatcg cttaagataa attcaggaca
    30301 ctaaatagta caggaagtag actaaaactt ttaaaagttt taagtctatc tatttggcaa
    30361 gtttaaaaaa taaaaattcg gtatcaaaaa actgttaccg ataacatttt tgaaagcgtt
    30421 gtcttttgct tctctatcac ttatagtgat gacgtcatat taaaacacaa ggaggaaatc
    30481 aatggataca gctgcaattt atcatcgacc ggaaagtgaa tatgcatttc tatatacgaa
    30541 tacaagattt cgtattcggc ttcgtactag gaaaaatgat atcaaaaaag tatatgtgct
    30601 atgtggagat ccatatacca taacaactga aaaatggtat caaaaacaac gaccaatgaa
    30661 aaaatgtcta agtaccaatg ttcatgatta ttgggaaatt gaagtgacga gcgaaacaag
    30721 tcgcttacag tatgcgttcc atgttgttgg ggaagataac acggactgtt tttacggtga
    30781 tcaaggaatt tttccttatc gagaaaatgt gattactgaa ccaaattttt attttcgaat
    30841 accttatttt catcaaatcg atcgattcac tattccagaa tgggtaaaag aaacagtatg
    30901 gtatcaaatt tttcccgaaa gatttgcaaa cggggacaaa gcaaatgacc ccgaacacac
    30961 tttaccttgg ggaagtaaag atccagaccg agaagacttt ttcgggggag atttgcaagg
    31021 tgtgatggat catttggatt acttgacgga ccttggcatc aatggcatct atttttgtcc
    31081 catatttaaa gccacatcca atcataaata cgatacgatt gattattatg aggtggatcc
    31141 cgcttttggc gataaaaaac ttttaaaaaa cttgattgat gaagcacata aaagagggat
    31201 acgtatcatg ttcgatgctg tattcaatca tatgggtgtc cattcaccac agtggcaaga
    31261 cgttctcaaa aacggagaaa aatcgatcta taaagactgg ttccacatcc gttttttccc
    31321 agtagattct tatcagatga ctgacttacc agaaactgct gaaaatatcc catatgatac
    31381 ttttgctttt actccattca tgccgaaact aaatacagca aatccagaag tgcaaaaata
    31441 tttgctggat atcgcaactt attggataaa agaattcgat attgatggat ggcgtcttga
    31501 tgttgctaat gaagtcgatc atcatttttg gaaaaaattc agagaagcag ttacagaaat
    31561 caaaccagac atctatatcc ttggagagat ttggcattcc tctcaagctt ggctgcaagg
    31621 ggatgaattc catgcagtga tgaattatgc atttacagat tcgattaaag attattttgc
    31681 aaaaaagaaa atcacagctt cacaaatggt cagtggaatg aatcatcagc aaatgcttta
    31741 cagagatcag gtgaacgaag gaacattcaa cttattagat tctcatgata ctgccaggat
    31801 cttgaccctt tgccaaggta acaaagaatt gatgaagtct gtgatggcct ttatgtttct
    31861 tcaaaaaggg tctccttgta tctattacgg gacagaaata gggatgactg gtgaagatga
    31921 cccggattgc cgcaaatgta tgatatggga gaaggaggaa caagatctag agctattcgg
    31981 ttttataaaa gaacttgttt ctctaaggaa acagttgtct aagattattt ctgaaggttc
    32041 tactcagtgg ctaatagtaa atgatcgtga agataagctc tatttcacac ggaaactaga
    32101 gggacagatc atctatgttt actttaatca gtcaaaagaa ccttgggtag tagaacagga
    32161 aaatgaggtg attcttagtc aaaattgtca gttgttagaa gacgggaaag cagagatacg
    32221 acaatacgga tttttgatca tgtgttgaaa actgttaccg gtaacaacaa gaaagcgttt
    32281 gcaaatgaag atttgtgccc attataataa gggtgtaaca gcacgttgaa tacaaaggag
    32341 gaaatgaaga tgaaaaaaag aagtgtgaaa cagttgggtt tagggttaat ctctttagga
    32401 atcttaggcg gattagcggc ttgtggcaat ggtaactctt cagcagaagg ggaagccgat
    32461 gaaggaaaaa cgttaacagt ttccgttgat tctggatata aagattatat aaacgaaata
    32521 aaaaacactt tcgaaaaaga aaacgatgtg aaaatcaagc tagtagaaaa ggacatgttc
    32581 gatcagttgg aatcattagc gttagatggg cctgctggaa agggacctga cgttatgatg
    32641 gcagcatatg accggatcgg tgcgttagga cagcaaggac atctggcgga agtaaaactg
    32701 ggaaatgaag cagcttacga tgaaacagac aaagcccaag tgacttatga tggaaaaatc
    32761 tacggagaac ctgcagtaat cgagaccctt gttttgtact ataacaaaga tttagtcgat
    32821 acagcaccat caacgtttaa agatttggag aatctatcca aagacagtcg ttttgctttt
    32881 gagtcagaag caggaaaaaa tacaggattt ttagctaaat ggactgactt ttattattcc
    32941 tatggtttaa ttgcaggtta cggtggctat gtatttggtg atgatggcac aaatccttca
    33001 gatatcggtt tgaataatgc aggtgctgta gaaggaatct cttatgcaac agattggttc
    33061 aaaaatgttt ggccaaaggg aatgcaagac ataaaaagtg caggagactt cgccagccag
    33121 caattcatgt ccaataaaac tgcagcaatc attgacggtc catggcaagc gcaaacatac
    33181 aaagaaaaca atatcaatta tggtgtagcc aaaattccta ctctaaataa tggacagcct
    33241 tatcaaccgt ttggcggagg aaaaggatgg gtagtcagca attatgctaa aaacaaagac
    33301 ctctctcaaa aatggcttga ttatgtaacg aatcaggaaa atcaagaaaa attctttgaa
    33361 atggtaaatg aaatccctgc aaaccaacaa gctagggaaa cagcaaaggc taaaaacgat
    33421 gaattaacaa cagctgtgat tgaacaatat gaaacagctc aagcgatgcc aaacatccca
    33481 gaaatgggcg aagtttggac aggtgcagaa aacttgatgt tcgatgcagc atcaggttca
    33541 aaaacaccaa aagaatccgc agatgaagca gtaaaaacaa tcagtgaagc catagaacaa
    33601 aaatactgat taaaatgata accgtccatt tttataaaaa atggaacagg tgcttcagat
    33661 aaaagtggca agagcgagat ggaaaattat cttgctcttg ttgccattat cttaaaagca
    33721 gtttgcggtt tagcaagttt agagggggca ttcagatgca gcaagataaa acaagcaata
    33781 tcaacgaaaa aaaaatcacg ctttgttcac ttattccagg gatggggcag tttgtaaatg
    33841 gccaagcttt taaaggtatc gtttttttcg ccatattcgt cctattcatt ggtcagatgc
    33901 ttctgggcgg atttcatgca ttggtaggat tggttacttt gggaagtata ccaatggaag
    33961 atcattcatt atttattttg attgaaggca ctttgcaatt catcattaca atcattttct
    34021 tgatttttta cggtttgaat cttttagacg cttatcgagt agcgaagatg cgtcaagagg
    34081 gcaaaaaaat caatcggacg atgaaggaag tcatacataa tataggtgat gaaggttttc
    34141 cttatctatt gacacttccc gcttatcttc tcatgatttt tacgatcatt ttcccagtcc
    34201 tagttacatt gttcactgca tttactaatt atgacttcaa tcatattcca ccagccagtt
    34261 taattgattg ggtaggggct aaaaactttt ttagtatctt ctttttaagc tcatatcgta
    34321 atactttttt tgcagtcttt tcgtggaccg tgatttggac tttatgtgca acaactttgc
    34381 aaatcaccct tggtattctc acagcggttg ttgctcacca gaaatttatt aaattcaaac
    34441 gtattttcgg tatcattttc ttattaccat gggcggtccc agcttttatt actatcatga
    34501 gtttttcgaa tatattcaac gatagcgtag gtgccatcaa tactcaagtg attcctttca
    34561 taaaccagct tccttttgta gatatcagtg caatctcttg gaaaacggac ccgaactgga
    34621 cgaaagtagc aattatctta gtgcagggct ggttaggatt tccctatatc tatgtgatgg
    34681 ttacaggaat cttacaatcg atttcagaag acttatatga agcagcaaaa atcgacggag
    34741 caaatgcatg gcagcgcttt tcaaacatca cgcttcctgc tgtcttccta gtggcagcgc
    34801 caacatttat tacacagtat acggggaatt tcaataattt ctccatgatc tatctgttta
    34861 acaatggcgg tcccggaagc gtaggcggag gagctggttc tactgatatt cttatttcct
    34921 ggatctataa acttacgact ggaacttctc cgcagtattc tatggcttca gcaatcacgt
    34981 tgattatctc cgtcatcgtt atctgtgtgt cattgctggt atttaaaaag acaaatgcgt
    35041 tcaatatggg ggattaacaa tgaaaaaatt tcattcgagt gctcgattcc aaaaacgact
    35101 ttctcacttt tttacttact tttttctttt aatactgtca gtcattatca tctatccgct
    35161 tttgatcaca gcaagtactg ccttcaagtc aggaaatatt gcagctttta gtttagatct
    35221 ttcaagtgac tggactttag gaaactttac tcggctattc agtgaaacac tttacgggac
    35281 ttggtataaa aatacattga tcatttctgt cctaacaatg atcgtacaag tgactgtagt
    35341 aactttggcg ggctatactt atagtcgcta tcgttttatc ggccgcaaat caagtttgat
    35401 gttcttttta gtgattcaga tggtaccgac tatggcagca ttgactgcct tttatgtcat
    35461 ggctttctta ttagaagcgc tcgataagta ctggttcttg acaatgatct atataggcgg
    35521 tggaattcca atgaatactt ggctgatgaa aggatacttt gacactgtac caatagattt
    35581 agatgaatct gctaaacttg atggggcagg gcatttcagg atttttttcc agattgtatt
    35641 accgcttgtc aaaccgatgc tcgccgttca agcattatgg gcttttatgg gaccttttgg
    35701 ggatttcatg ttagctaagt tcctgcttcg aacacctgaa aatcagactg ttgctgtcgg
    35761 cttacaaaca tttatttctg atgtgacaaa ccaaagagtc tctctttttg ctgctggggc
    35821 aattttgatt gcactaccga tttgtctatt attcttcttt ttacaaaaga actttgttac
    35881 cggcctgaca tctggcggaa caaaaggata ggagcagagt atcatgcaaa catttccgtt
    35941 aaactatttt tccgcattac gtacgccaac tcaagtgttt gcgggacgca aactattatc
    36001 atggcctaaa tttttcttga tatttgtatt tttagtttcc ttgatggtca tgcctgtgac
    36061 tcttttttat gccaatcaga tccaagcgat tccattagaa caatttctat ccgttcattc
    36121 gctgatcgat gaacaaggaa cccaaaaatt ttctgaactt gaattatctg aaactgggtt
    36181 acaagcatcg caacaaacga tagctgtgac ccctgaaatt ttggtaggtg tgtctttatc
    36241 tgagaaacaa caatccgatc atggaacttt tattgatttt gagaaggaac aatgggtgat
    36301 ccaacaaaag gataaatctg gtatacgccg ctatacgatg aattatagcc catctttcca
    36361 accagattct gtacgtacgc ccgaagattt ccaacgattt ttagaaagag aattttatgc
    36421 cagtaatcgt ccaacaatca ttttatctta tagtttaagt cttggtcttg tcctatttgt
    36481 catgacgagt ctcattttat tcggggcttc ctttttcttg tggatgacaa gaaaaagcca
    36541 actttcatcc attcatacat tcaaagagag tgcaaatttg atgctgaatg ttatgggaat
    36601 aggttccatg gcagcagcag ttgtagggtt tatccacttt gactttatct tgatgctaag
    36661 tgtccaaaca acgataactg tcttgctgct tttatgggtt tttgtcaaaa caagattcaa
    36721 agataagcgt gtcgaatgac aagtttaagc gatttatgcg acaatgaatg tgaaaaaaat
    36781 gaaaaataaa gtagtttttg aaaaatttct gaaaaaatta aacttcttag ttgattcttt
    36841 tcttttttag tattaacgta atagggtagt ttttttaagg aggaaaatca tgttagagaa
    36901 aactttatac aatcaattat tttcacgttc tttctcgctc cctgtcgaag taaattattg
    36961 ggacggtaca acgaaacaat acggagatac ggacactcct ccccaaatca aaatcaatat
    37021 ccatgaagaa atcccaatga aagagattac aagtaacgct tctttggcac taggagaagc
    37081 ctatatggat catcgaatcg agatcgaggg aagtatccaa gcattgatca acgatgctta
    37141 tcagcaagca aacagctttt tacgaggaaa agattatcta aaatggctgc caaagaaaga
    37201 aaaacatacg aaacaaaaaa acaaagaaga tatccatgcg cattatgact taggtaacga
    37261 cttttataaa ctttggctag atccaacttt gacttattct tgtgcttatt tcaatacacc
    37321 tgaagatacg ttggaacaag cacaaatcaa taaagtccat catatcttag acaaactctt
    37381 tatcaaagaa ggcgaaacgt tgcttgatat cggttgtggc tggggaacat tgatgttcac
    37441 tgctaccaaa gagtataatg tcaaggcaac tgggatcaca ctaagtgaag aacaatacga
    37501 tttgattacc aaaagaataa aagaagaaca tttagaagat aaatgccgtg tattattaat
    37561 ggattaccgc gaactaaaag gcgaaacgtt tgatcatatc acaagtgtag gtatgttcga
    37621 acatgtaggt tctgaaaatc ttgaaggtta tttcaaagtg gtaaaagatt tattgaaacc
    37681 aaaaggaaca gctttgatcc atggaatcag ccgacaacaa ggcggtgcga caaatgcttg
    37741 gatcaataaa tatattttcc ctggcggtta tgtccctggt gttactgaat tagttgataa
    37801 tattacaaaa aacgatttgc aactgattga tttggaaagc ttacgtcgtg actaccaatt
    37861 gacattagaa cattggacaa agaattttca tcaagtccaa gatcaagtca cgaaagaaat
    37921 gggtgattcc ttctatcgaa tgtgggatct atatttacaa gcttgtgcag cttcatttga
    37981 atcaagtaat atcgatgtga ttcaatattt gcttgttcaa cctggaaaca atgacatccc
    38041 aatgcatcgt gcataattga ggcaaaagta ctgtttaaag actatttaaa aagaagctaa
    38101 gttttatgat gctccagaag tgaacttttt tgtctaactt ctaggattgt ctctaaagct
    38161 tagtttcttt ttctttatat tttcataata aaagtttggt tctttaattt ttaaacatga
    38221 cagaaaattt tttcttcgtt atacttgtaa tagaatacta ttttataaca aaggggatcg
    38281 aatcaatgaa aaaaactgtt atttatacta gtttatttgc agctttgttt ttagctgctt
    38341 gtcaatcaaa taccaatcaa ggcacatctg ggaatacgtc ttccagtagc gaacagcgct
    38401 cttcacaggt atcggactcc tcaacaaaag caagcacatc ttcgtctagc cagacaaaaa
    38461 gttctagtga agcaagtact cagtcagata tcaaagtgtc tgcagctcgt gcgatcgaat
    38521 tgttccaaga taaataccca gatactgcaa ttactagttt ggaattagat agtgattggg
    38581 gatcttactt ctacaagata gaaggtgtcg atgatcaaaa agaatacgaa gcaagaattg
    38641 atgctcaaaa tgaaaaaatg gagacagaga atccagaaac tctagatcga gatgaacaaa
    38701 atggtcaaaa gaaaaaagaa gatggtctgg atgttgataa attgatcacg attgaggaag
    38761 cagcaaaaat cgccgtcgac aaagtaggaa gcggtacggc aacagattgg gatttggata
    38821 aagatttagg tactacttat tgggaagtca aagtaaaaga cggcaatcaa agtacatcag
    38881 tcaagatcaa tagccaaaca ggcgaagtac tgtcaactga acaagatgat taagaatttc
    38941 ttcggaaaac aagagttgat ttttctttta gtcatgatac actagacaaa ataacttgtt
    39001 tgaaggagcg atttacttga gtttagaaac gacctttgcc aatcatatct ttgccaatcc
    39061 tttgatgaat gcatctggtg tccactgcat gactacccag gaattagatg aactggctca
    39121 ttcagaagca ggagcattta tcactaagag ctgtacgatc aatgaacgaa aaggaaatcc
    39181 cgaaccacgc tattttgatg ttcctttagg gagtatcaat tctatgggac ttccaaactt
    39241 aggtttttct tattatctag agtatgctct tgcgtatgaa aaagtgcagg aaaaccaaaa
    39301 tcaaccgtta tttttttcca ttgccgggat gagtgtccag gaaaacttgg aaatgcttga
    39361 gaaaatagaa aaaagtgggt ttaatgggat cactgaatta aatttatctt gtcccaatgt
    39421 gcctggaaaa ccacaactag cttacgattt tgaggccact tatgaaacac tgaaagaagt
    39481 attcagcatc ttttctaagc cgctaggaat caaattgcct ccttattttg attttgctca
    39541 ttttgatcag atggctgata tcttgaatca gtttccattg acctatgtca atgctatcaa
    39601 cagtgtgggc aatggtttgt atatcgatac agaacaagaa gcagtagtca tcaaaccaaa
    39661 agaagggttc ggcggcattg gcggagagta tatcaagccg actgctttgg cgaatgttcg
    39721 cgctttttat acacgtttga aaccagaaat ccaaatcatt ggtacaggtg ggattcggac
    39781 aggacaagat gcatttgaac atctgctatg tggcgcaagc atgttacaga ttggtaccga
    39841 gcttcataaa gaagggccgg aaattttttc tagaatcata aaagaattaa cgcagattat
    39901 gtcagaaaaa ggatatacgt caattgacga atttaaaggc aaattacgca ccatttcata
    39961 gcaaagagac gaaggtcatg attgatcttc gtcttttttt ataaaaaaca ctcgtctgtt
    40021 cattcctgtg caagcgtact cattgtatgt tagacgaact tgtgggaaaa taacagaggc
    40081 aaaaaggagg ataatatgaa tgatgcaaca gaattagcaa aagagcttaa agaaaaagaa
    40141 tttagttttc aagaactagt tacggatata cagaaaaaaa taaagaagca aaatcatgaa
    40201 ttgaatgcgt ttgtcgcgct tgaaccattc gagagtaatt cccacgagct attgattccc
    40261 cagtcagaaa aagggccatt ggctggtatc ccatttcctt taaaaatgct cggtcaagaa
    40321 aaaaagggat ggctagctac ttcaggatct cgtttatttg aaacacaccg agcttctcat
    40381 acatctaatt atgtgcggca agcagaagcg ataggtctag ttccttttgg acaaaccaat
    40441 gcgccagagt ttggtttcaa aaatattaca gacccagtca tctatggccc agcaagaaac
    40501 ccttggaacc ttgaatgtac accgggcgga tcaagtggag gagctgctgc tgcagtttca
    40561 tcaggaatcg ttcctttagc tggtgctagt gatggcggtg gttctattag aatacccgct
    40621 tcgttttgcg gattgattgg gctgaaacct tcgcgaggga cgatgccagt tggtccatat
    40681 gcttggagag gatggcaagg agctgctatt gatttcggct tgacagtttc tatgagagac
    40741 acggaggctt tattttatgg gatgagaagt atccattccg gtgcgccata tcaagtatcg
    40801 ccagttgagt ggcaaacaca tccaagaaaa aaacggttga agatagcttt ttgtgttgat
    40861 tcaccgatcc actcacagat tagtgaagag gcagtacttg ctgtaaaaaa agctgtagat
    40921 ttccttggaa aagaagggca tgatttgaca gagattcctt acccactaga tggtcgtaaa
    40981 ctgatcacgt cttattatca gatgaatggc gcagaaacag cagcaatgat ccgctcgatt
    41041 gaaacaggca tccagcgagc tgtcagaaaa gaagaacttg aacccatttc ttggactttg
    41101 ttccaatatg gtcagaagct ctctgccgct acttacatcg attctctgca tgtatgggat
    41161 gaagcagcaa ttgtcatgga aaacctacat caagaatacg atctattcct ttcaccaacg
    41221 actgcattta ccgcccctaa aatcagcgaa gatttgcaaa gtgatgcgat aagagcacag
    41281 atggaacaca tcagtgattg ttctgaagta gaaggtttag acgttgtttc ttccatgttt
    41341 gaggagagct tgaagatcac accttataca cagttggcta atctgactgg acaaccagca
    41401 atcagcttgc ctactcattt gacaaaagaa aacatgcctc taggaatcca atttatggct
    41461 gccagaggaa gagaagattt gctatttcaa atcggctatc tatttgaagc aaatcatcag
    41521 ttccatttac caaatccatg gaaatagcag aaacaaggag aagaagaatg aagaaaaaaa
    41581 gattgtttgc tctaataact agtgcctttt ttattttaag cgcttgcggt acagctgccg
    41641 ctaatcagga agataacagc tggagtaatg tagaaaaaaa gaaagaatta gtagtagcga
    41701 cttctggcac actgtttccc gcatcttatt ataatgatca aaatgaatta gttggttatg
    41761 atgtagattt ggcaaaagag gtggctaaac ggttaaatgt caaaatctcc tttaaagaat
    41821 acaacgtgga tggacaaatc acttctgttt caaaaagaga atcagatttt gctgcgaacg
    41881 attttggtat cacaaaagaa agagaaaaaa aattctccct ttcagagact ttcaaatatt
    41941 catttgacag tatgatcgta cgaaaaaaag atgattcagg aatccactca cttgaagatc
    42001 ttaaagggaa aaaagcagct ggcgaaccca atactagcta tatgcgttta gcggaaaaac
    42061 acggagctaa attagtcaca tatgacaatg ccacgaatga tcagtattta agcgatgtag
    42121 caaatggtcg aacagatgtt attctaaatg attattatct gcagaaaatg gccgtatctg
    42181 ctttaccaga tatccctgta aaaatactgg agaacgttta tttcaatgaa aacgaaagtg
    42241 gttttttatt gaaagaagga aatgatgctc tgaaaaagaa aatcgatggc gtattaaaag
    42301 agatgaaaga agatgggacg acaaagaaaa tatctgaaaa atattttcaa actgatgttt
    42361 cagtcaaacc gaaagaaacg atggctgagt cggtgagtga gtgatgtact ttcctctaat
    42421 tgatttttcc ctcatgtgga cttcacttcc tttcgtactg caaggcttgg tatacacatt
    42481 agggattggc ttcgtgtcgt ttcttttagg aaatctggta gggttgcttt tgacagtttt
    42541 aggtcttttg gattggctgc ctctgaatgt atttattcgt ttttatttat cgttctttag
    42601 aggcattccc gcactagtcc tgctgtttct gttatatttt gggttacctt atcaattaag
    42661 tgccttaacg gcttcagtca tctgctttac gattaccagc agtgcattta ttggtgaaat
    42721 ctatcgagga tcactagcag gcgtttcttc aggtcagtgg gacgctggtt tagcttctgg
    42781 tttttctttc tttggggtat tgaaatatat cgttttgccg caagcttttc gaatctcagt
    42841 accggcactc agtaacgtag ctatggatct agtgaaaggt acttcgttag cagcaacaat
    42901 cacagtgcca gaaatatttc aaaaagcaaa gatcataggc ggtcggacat tcgattattt
    42961 ttctctctat attttagttg cactgattta ttgggtcatt tgtatcggga tcgaaaaagt
    43021 gcaacagtat ttagaaaaac gttctatgca tcagtcaatc tgaaaaatag aaatggtgct
    43081 agcgtggctg gcaccatttc tattttttgt ttcttgtata ttctgcctag tattttaaaa
    43141 ccatttcatg taaaatgtaa atcgaaaata tgttcggagg tagaaaacat gaagaccccg
    43201 ctaaccatcg aaatagaatc ctcgttatac caatattgca tcgagcaagg cggcttggtt
    43261 gtagaagaag tcacgatgcc tgatgaccaa ggaattgtag atacgcttag ctgcttgaca
    43321 aaatttgatg gaagccgaga atggcgatgc tatgagctga aagtgacaaa agcagatttt
    43381 cgctctacag ccaaactgtc atttgttgga cattataatt attttgtttt accaagtaaa
    43441 ctatatgaag aagtaaaaac tgaaatccct acaggaatag gtgttttagt gtatcgtccg
    43501 tacacggttg aagaggagat gcctgcctct ggtacatttc tgattgcgaa aaaagcagca
    43561 aagaaagagc ttgctgtacc ggaagaagct ttgacaaacc gcttcatggc ttctttattc
    43621 agggaagtaa gaaaagcaaa gcaaatggag cgaggcgtaa aatattttcc aacagatcaa
    43681 ttgtacaaag aattgaaaag acgttcagaa aatcaagatc cattttctaa cgaacgatat
    43741 tatgaacggt ttttagagga aatagctagt caggcaatca atgagttgca agaagaagtt
    43801 atcgcgcttc agcatgatta tgaatatttg aggcaacaac agcagatccg tcggttgcct
    43861 acagagccat tggagtgaaa aatatgtact atccttattt aagaggaaaa caatttgacc
    43921 tattagcatt aaaagaagca ctgtcgcgag gattgctctc caataaaatc caaccagtga
    43981 tcgaaccagt acgtgattcc gctacgctta aaaatgtgat cgaattattt caaaaaaagc
    44041 accatccaat cgctgtgatc caaaatcccc aagtaggaca attcaaatta ttcgatcagc
    44101 atgtgcacag ttggacagtc aaagaaaata gctctgtcgt ccctgcacag atcttaacgc
    44161 cagaaaatct cagtgaagta ctggattcac ctccagcgtt tcttgttttc gatggacagc
    44221 actacccaaa agatacagag gtgtggaaac agttggcagg agttgattcg aaatttttga
    44281 taccagatac tagtcgcttt cgcatctggc tgcccgaaaa caaaattgtg atccgtgact
    44341 cttttcaaac gagaaagcat gttgaaagtt atgcagataa aacagatgac ttttttagtg
    44401 atgactatct ttttttccac gcagacggat atattggatt ttctgatttc acgatcgaag
    44461 gtagccgtta tttcgataaa gggttcccta gccgagcgct tgctatccat ctaacgtata
    44521 ttgatgctta cggcaatata cgcgtgaaac attttgtctc tgacagtaac gactctgcta
    44581 aagaccaagc attgaagttt cttgaagcag gagataaaat gaaaaaatgg atcatgcgtc
    44641 accatcatca actcttgatt acttcaggaa tgattgaatt attggctctt taccagcaac
    44701 aaaaattccc tggactggga gtgttgaaaa agtggtcact tatgcatcat ttggaactta
    44761 ttagtcacct gctagatcat ccaaaagatt ggcttaaata ttattcaaaa gttcaggaac
    44821 tatatgaagt gatccaatga ttagataatg taaatgaaaa aggaatagaa aagaggaaac
    44881 tggatgtata ttcggcaaac aaggaaagaa gaagtagaag aagtggtaga aatcattaat
    44941 gccgcagcgg atttcattgc ttcgcaaggc tctcctcaat ggcaaaacgg gcagaaacca
    45001 acaaaagaaa cgattttgaa cgatattgaa agaaaagaaa gctatgtatt aatagtggaa
    45061 gatcaaattg ctggaacagc tgcattagtc tcaagcgtgg atcccgttta cacaaaaata
    45121 gatggtagtt ggaaagaatc aactggtcct tatttatcga ttcatcgtgt cgctttagca
    45181 gaaagtactc gaggaaaaaa actagcaaaa ccgttcttag aacatttgtt gacgattgca
    45241 gccagcaaaa atatccaaga tatccgtatc gatacttatc cagctaatga accgatggaa
    45301 aagaccatct attctgctgg attcacttat caagggatga ttgaatttcc ttttgaacac
    45361 ggcgaaagaa aagcatatca aataatcatc aattgactat aaaatcatct gagcaaagat
    45421 aaagacatta acactactga aaaaaacaat catatgatag ccaagaggtt gtaacagaag
    45481 tggccagctt caaaaaacaa gaaagaattt ccgaaaatgc ttctcaaatt tttgtggaat
    45541 tttagcgtat tttacgaaat agctgctttc tgaaactccc ttcatcgaga ggtcgtgaca
    45601 tagcttttgt cacgacctct cggcttatcc tacgagtatt attcgataca tttatatcaa
    45661 taatcctttt tttattttat ctgcagcttc ttggaacgct ccatcgtttg acacgactaa
    45721 aagtgagggg atagctttca aacgtttcaa ctgtgctaaa tcttctacat aaaccgccag
    45781 tctggctgaa atctgttcag atgaatctcc acgttttttc aggcgcgatt gcaatgtttc
    45841 tttagagatc gtaataaaga taggacggac taccgtcccg aaatactcat ataaatgcca
    45901 aaaaccattt gctgtcaaaa cggcgtaaca atttcctact gtcagtttct ttttaatttc
    45961 tgctttactg gaaccatatt tatgttgagc atattggtcc cactctgcaa actcatttcc
    46021 cttgatcatc tgattgaatg tattgtcaga aacaaaataa taatcctctt gatctttttc
    46081 cccaggtctt ggtgatcgat tcgtgtaagt aatgatcttt tgttccggct gaaaaatagc
    46141 ttctgcgagt gaagtttttc cagaaccaga aggaccgata aatacatagc aataattcat
    46201 tgtcatttct cctttgatga ttgaacaagt gaaaaagctt tggaaaatat ttccaaagct
    46261 tttaaaagta actttgcttt tttgtatatt ataccagcaa gccagtcaca atagcactta
    46321 aaaagctgac taaagtcgct gttagcaaaa ttttcaatcc gtgttttgcg acaagatttc
    46381 ctttttcttc atttaatccc ttcatcgcac cagaaatgat cccgatagaa gagaagttgg
    46441 caaatgaaac gaggaagaca gatataattg ctgttgtacg ctcagtaaaa tggaaattac
    46501 catttgctaa ttctgtcata gcaacaaatt catttgtaac cagtttagtc gccatgatac
    46561 taccggcatc cactgcttct ttccatggga ttccgctgat gaaggcaaga ggggcaaaga
    46621 tgtaacctag gatctcttgg aaagtgatgc cgaatatccc gtggaagata gcattgatca
    46681 tggcaatcaa agcaacaaaa ccgataagca tagcagcaac cgtgatcgcc acatggaaac
    46741 catcaagaat gtattctccc aacatttgga aaaatgtctg ttctttgttt tcttcaatga
    46801 tcagctcatc ttctttttct tctaatacat agggatttac aattgaagcc agaatataac
    46861 cgccaaataa gttcaaaaca agggcagtga tcacatattt agaatcgatc agtgccatat
    46921 aagatccgac gatcgacata gaaactgtag acatagccga tacactcatg gtgaacaaac
    46981 gtttctcaga taggaagggt aattcctttt ttatggaaat aaaaacttcc gattgtccta
    47041 aaatagcaga agctactcca ttataagatt ccaatttgcc catcccgttg attttactta
    47101 atcctagacc aacagctttc ataaataatg gaagaatctt gatatagcgt agaataccga
    47161 taatagcaga aataaataca attggcatca atacggaaag aaagaaaggt gcacttcctt
    47221 tatttgctac accggcaaaa acaaagtcaa caccttgccc agcaaaagca agaagatgat
    47281 caaacatttt tgccaataca gaaacaaccg ctgtaccaaa agttgtacgt aataatacga
    47341 aaccaagaac aagctgtaaa acgaacatca caattagtgg tttcaatttg attgcttttt
    47401 tgttactgct gatcaaaaaa gcaagcccta atgtgacaaa taaaccaata atacctaata
    47461 aataactcaa ataatcactc ctattccaaa ttccgtttta ttttacctgt tttgcaaata
    47521 aaatactaat ctttagtgaa attttcatta cttttttaga gtgaaacgca ttcattttcc
    47581 attagaaaat aaagcgaaca aaataaaagg tttaaaaagt gtaacgtctt agtaaagtct
    47641 ataaaaaaac gaaactatcg attaagctaa tagtttcgtt ttcaacattt ataagtaaac
    47701 tttttctatt ggtaatatag attttcggaa gggtagacag gtgcgcaggt aatatcgatt
    47761 cctagttttt tcaatgtttg ttcatcattt ttattgacca tcacagtaga gtgggcttgt
    47821 gctccctcaa gttcagctag tttatcataa gcaacttgag cgattggatt cgttactgca
    47881 ctgattgata aagcgatcaa gacttcattg atgcttagtg catccaaaga ggaatgaagt
    47941 gtctttgatt tcaatccttg tattgtttca agaactaatg gtgacaataa aggaatgtca
    48001 tctgcgatat gggctaaatg ttttactgca tttaagataa ctgccgctga cgcatccatc
    48061 aatgaacttg tacgcccggt aatgatgact tcatctggta attcgattgc aatcacagca
    48121 gaaggatctt ttgtaggact ttgcgcttga atcttatctg catagtcatg ggcagggact
    48181 accacgtttc ggtcttcagg acgtaaaccg acttcttcca taatcagttt gattcgatta
    48241 actgcttctt cgtcgatcaa tccttttttg aagtcgcatt ctgtttggaa ataacgacgg
    48301 atgatttctt gtttagaggc ttcttggaca acggtatcat ccacgatccc aaatcctaca
    48361 cgattcacac ccatgtcagt aggagattga taaacagatt ctttaccagt aattttttca
    48421 ataatacgtt tgattacagg aaatgtctca acatcccgat tatagttcac agctacttta
    48481 ttgtaggcat caaagtggaa ggaatcgatc atattgacat cttttagatc gactgtggct
    48541 gcttcataag caatgttcag cggatgtttc aacggaacat tccatactgg gaaagtttcg
    48601 aacttggagt aaccagctgc atgtcctttt tggctttcat gatacagttg gttcaaggaa
    48661 gtagcgagct ttccacttcc tgggccagga gctgtcacta caacgattgg tttagttgtt
    48721 tcaatatact cattttttcc aaaaccatct tctgagacga ttttttctac gttgactgga
    48781 tagtcttcga tttctgagtg tttatagacc ttgatgtttc gtctttctag tttattgata
    48841 aagactttcg tggcaggctg tccactatag cgagtgataa cgacactgtt gattaataag
    48901 ccataaccac gtaattcatc gattaaccgc aagatatcca tatcataagt aatcccataa
    48961 tcaccacgga tcttattacg ttcaatatct ccagcataga cgcaaatcag tatttcagct
    49021 tgatctttca atttttgcag caatttgatt ttcgcatctt cttcaaatcc tggaagtaca
    49081 cgtttcgcat gcttgtcgtc aactagcttc ccaccaaatt ctaaatataa tttgtcatag
    49141 tggttcactc gttccaaaat atacgctgac tgctcttcaa tatatttttc tgaatcaaaa
    49201 ccaatttttt tcactaggtt ccctccttaa gtactaaagc attttttcat ttttttgagg
    49261 attcgtcaac tggaagagcg aaattcctca aaaaaacaaa gaaaatggtt taaaccaact
    49321 tgtctagata gttattcatt ggtatgatag tttttgataa ggaaggtgct acatgaaaaa
    49381 aagacagaaa aagaaaaacg catataaaca ctatatccgt tcgattttta ccggttatga
    49441 aagaatgctt gaagatcccg aattggaaca attgacgttt acttatctaa acgaagaaac
    49501 gcagctaact cgtgatgagc atcagcgcat tcatttcaca acaagagatc tgcctagtaa
    49561 ataaaaaata agataaaggt catcggattc gattctgtcc tatcagatgg aaagactagt
    49621 tgatcgaaaa aaaggctgta ccaaattttg gtgcagcctg ttttatggag cattgcccgc
    49681 tcttttttat aacaattttt tacagaaaat ggtactattg aagtattaat aagtgaaaaa
    49741 cagatgagta agaggaggca agtagtatga aagagccaga tacaaatgca aattatgagc
    49801 cagacgaact agaggagacg aatgcggatc aggatacagg acaagaatcg tcttcttttt
    49861 acgatatcaa agaaaaagca agcatgaatc tttcccaatt attagaagac ttacaggctt
    49921 ttgaaaaagc tgtccgcgaa gaagatatcc ctgagatcta ccgtttatac aatggccgat
    49981 tgaatgaaga attaaaaaga agctcaaatg aaaatcacga gatcgatcaa ttgctgatgc
    50041 gtaagatcca tgatcgtttt ttacaggaat ttccttttat ggaacaagta gaaaacatct
    50101 cgccaacgat gagctattac aaaatcggca cttattacca tgatcggccc acggtcggta
    50161 ttgatgcaag tctgccagaa atttttgttt tgcctaagat cgatgaagag tgggagaaat
    50221 attcccaacc ggagtcaacg gactatgaca aaaaaatcaa tgagctagac gcaaaggtga
    50281 tcactgctca gacagaaatt gaacgtttag atgaacaaat aaaagaaatc aatcgacaaa
    50341 tgactgattt gaacgacaat aaaggattct tgaatcgtaa aaaaatcgag gaagaaattc
    50401 aagaattaga gaagaagaag caagtactat ctaatgaaaa attaggctgg cttccttata
    50461 ttgagacgcc tgaaacaatc cagcagcaaa aagaagcatt gaagcaagaa gcaagagcag
    50521 accagcttcg tgcagccatc gtagaaaaag aacaaaggca aatcagacgc tatttcggta
    50581 gcaaagaggg attcggtcaa gcaatccatg aattcttgat gaattatctt ggcaatgaga
    50641 atcctaataa tcaatctaat gaaggaggtt ccgagtatga atgaacacga tgaagcagaa
    50701 tggacaaaaa atgaagaaca aacagaagat catgaagaaa cgaacacttc attggaagaa
    50761 caaacaagta atcctctgga tgacacagaa gaaatcccta tgctagagga aacaaaaata
    50821 cacgaaaaag aaaaagtaac tccgacgaat acgaatactg cagaaaacac ccatgcttac
    50881 gaaataactg aaaatcccgg gtatttagaa ggaaaagagc aagatcatca agatatcgtc
    50941 agtttgattg aaacagcgga agcagaatta gcggatttac gtatgagaaa agatttgatc
    51001 gaatcagatt ttccacaatt attagaatca tatgatcgtt ttatattgaa tgaagaacca
    51061 atctccacga tcggaaagac aagcctgatc gaatacttca cgtatgaatt actgaaaccg
    51121 ttgaatgata ttggtctgga acggtcaaat tcagcttatg acacatggaa aacaagacat
    51181 ttttcgatca attatacgtt gaatggacaa aacgaattag tcttttcctt tgtattaccg
    51241 accatcgatc aacgatacca agtggaatcg atgagtctcc taaacgtatc accagagaca
    51301 atggaaatca atgtccaaga tgaccgggtg ctttctttga tccgacactg gtcagtggat
    51361 cgagtattct ctgcagggca gatcacgata ttcaatcaca aattgaatca attattagcc
    51421 catgcaagaa cacttggttt taccgttaat cagacattac tagacaatac gaagccactt
    51481 cgtttgaatc ttcagagcga atttgaattg acgaatgaag tattggatga tatttttatc
    51541 gtggcaatga aaaatccatc ctacgatatg gaaaagatca acgaaactac ttatcaagta
    51601 cgattagata aaggacagtc tttaacgata acaacaaacg aaaaagatca aacagtcttg
    51661 tcgatctcat ctggagacta cccacgatct gtcattgatt tctttatcaa ttacgaattc
    51721 ttggtcccat taatggtgag aaagtcctga ttggataagt tggattacca gatgtcattc
    51781 agataattct gttccaaagg acttgcggca gttatccaga ataattgtca caagtctttt
    51841 ctgtatgtac taaatggacg tgaataactt gctgatgaag gagggatttc attaggaatg
    51901 tccacaaata aaatagcaca gcttagctta ttgtctgctg cttgtgtagc aggtaggatc
    51961 gcttttcaat ttattccgaa tttccagcca atgactgcta tttttttatt tatagtactt
    52021 tacttaagct taaaagatgc gttaattgtc atgagtcttt ctattgcgat cagcagtttt
    52081 tattttggtg ttggaccatg ggtcatcggc caatggatca gctatactgt tgttctgagt
    52141 ttgttttcaa tcgtctgctt gagaaaaaca gtgcaaagga atctatggtt aaagggagtc
    52201 tgtttttttc tggcgggcat ggtttacgga ataggtatga ccgtttttga tacgctgtta
    52261 tatcgtttgc ctcaaccttg gatctattac cttcaagggg tgtcgtttga tttgatgcac
    52321 agtataggca atgttgtgtt ctttcttgtt tttctgccag tcgtcaaacg tttttacaat
    52381 cattcaggag gaaaaaatga aaaaaataat ttatagtttg cttgcaatga gtgtcagtat
    52441 actcattttg acaagttgca gtacaaccta tacacaatcg gcttccaacc aaaaggagga
    52501 agtaaaaaca tcgcaaaaag caacaatcac gttacaagaa aatggtcaaa acttttcgga
    52561 aaaagaagtg ttcttcaaaa aaggcgatga tttactgagt attttgaaac gaaattttga
    52621 agtcaaagaa gataacggct tcatcacttc gcttgaaggg cactcacagg atgagaaaaa
    52681 tcaactctat tggatgttta ctgtggacgg gaaaagtgct actactggtg ccaaagagat
    52741 caaattgaat gatggacaat cggtcatttt caatttgtct aaactataag tttcataaaa
    52801 aactgttaaa gggcgaatat tgccataatt cagtgagttc agttgatgaa agaaggaaaa
    52861 taacatggaa aattttaaaa aaagcggaat gttttccgta attgctgctc taggggctaa
    52921 tattctagtt gctatcagca aatttgtcgg ctatgcaatc agtggcagtg ccgccatgct
    52981 aaacgaaagc atccacagta tcgttgattg cagcaatcag attttgctgt tattcggtga
    53041 taaacaagcc aataaaggac agagcgagtt gcatcaattt ggtgaaggac gagcaaaata
    53101 ctttttcagt acaatcgtcg caatgatgct tttcttcggc ggtggggcac ttggggtgat
    53161 ggaagctttt gaaaagttga cgcatccatc ccatgaagtg ggtaatccga tcattgttat
    53221 agcaatactg ttatttggtt tggtaatcga aggaagttcg ttacgcgtgg caatgaaaga
    53281 aatcaaagaa ttgaatactg aaaaactttc cacgatgcgc tttttgcgcg aaagtcgaca
    53341 cagtgaaata ctgattattt ttacggaaga cttgtgtgct gtaatcggtt tggtcttggc
    53401 tttagcagga acaatattga cttatgcaac cgggattgct gcatttgatg cgatcagcgg
    53461 attgctgatc ggtttcttgc tgatgggagc cgccattttc ctagcaaaag aattttatag
    53521 tctgatcatc ggtgaaagcg tgacagcaag cgatttatca aaaatcaagt tagcttttga
    53581 acgtcctgag atcagtcggc tgatcgatat aaaaacagtt catttaagtc caacggagat
    53641 tttagttgca gcaaaagcag atatcgttgg taacaaagag aatgaagctt actcggtcat
    53701 caatgatatt gaaaaaaata tgcgtcagtc tcttcctgac aagaagatgt atatatacat
    53761 tgaaacagat aaatatgacc caaattattc tcgtaaataa aacgtttatt catgaattga
    53821 agcaaaaatg agaaaaatat aatcttgttt ttaaataaaa cggctacaat ttagcgaatt
    53881 tatgttacaa tgagtccgct gtttatttgt tgtaattaaa ggagatattt taatgaacaa
    53941 aaagaaaagt gcgccatggc ttcaagcttt gcatgcagtg atgccacttt gtataagcta
    54001 tataccagta ggattagctt gcggagtatt gttgcaaaaa gttggatttg atcctctctt
    54061 atcaggactg ttatcgattc tggtcttttc cggtggcgcg cagtttttag ttgcatctat
    54121 gcttacgacg caagcatcat ttgcaacgac attattgatg gttttctttt tagaattacg
    54181 ctatacatta ttaggagcaa gtcttgccgg ttttatgaaa aaagaaaagc ggacgttttt
    54241 ggctgtcttt tctcaatcac tgaatgatga aaactatgcg gtgaactact taaagttttc
    54301 aactgaccct tcctggaata aaagaaaggc tttatatgtc aattggttct caatgactgc
    54361 atgggccggt agcaatatga tcggtaattt tttcggctcg gtgattcgag tagatgctga
    54421 ccttgtccat tttgctttga cggccatgtt cattttcatg tttatcatgc agatgaaaag
    54481 cgcactactg atctttacag gtttattctc aggcgtatta ggggtcgtat tcatggtatt
    54541 attccaaaat actttcggat tgattgcagc aacagtcatt gcttcatttg ccggatttat
    54601 gctggagaag gcattcaaaa aagaaaaagc taagaaacta agagaccgcg gtaaagatgt
    54661 caatgagccg ctcttcaact tcccggaaca ggaggccaat caccatgact aaactatatt
    54721 tgctactttt agttgcttgt ctgttcatcg tggcatatat cccgcgcttg ttcccgatgc
    54781 tttattttac tcatcgaaaa gtgccatcct ggttcagtga ctggatgaaa tatgtaccgg
    54841 tggcattatt tgcggcgtta gcttttaaag atgttttcat tactcatgaa catctggata
    54901 ttgcttggaa tatcaaaata gctgcaatga ttctagtagc aggcgtggct tacaaaacac
    54961 gttcgatggc gttgtcagtt ttgacaggac ttgcgtctgt ctttttgctg tctatgcttt
    55021 aaactgtttt attttattaa aaacagagat tgcgacataa gttgttcaaa ctgatctatc
    55081 cgaactgcat ttgcaacagt caattctgga tgcaagttta ttcgtaggga taaaaaagat
    55141 tagtgttggc ttatgatgca agctcttttt tattttagga attagagagg gatttgtcct
    55201 tctatgattt tttgctataa tagggaagat gtttatttta tgaaagaata gttgagggaa
    55261 tttaaatgaa taaaaaattg atgcaaggaa cattttggct aacctttgct aatcttctat
    55321 gtaaagtttt aggggtagtc tatttgattc cctggctaag tatgatgggg aacaatcaag
    55381 atggtatgct tgctacgaca ttgtataatg ttggctatct tccttatgga ttgttcctga
    55441 tgcttggtac agtcggattt ccaaatgcga ttgcaaaaaa agtagctgta gccacaaaag
    55501 aaggagataa cgctgcttgt cggctgattt ttagaagtac gatcaatatc atgtttgtca
    55561 tcggtatcgc ctctgctgca ctgatgtatt tatttgctcc tttactagcc ggaatcagtc
    55621 cgattgctaa cgttaataat gggatactag ctatcagaag tttatgccca tctttgattg
    55681 ctatcccaat tcttagtgca atgagaggat atttccaagg aaaaaatgat ctgcggcctt
    55741 atggaacttc tttgattatc gaacaggctg tgcgagtgat cgttatcttg gctggtactt
    55801 attacttgcg cgtattgact gacggaacca tattagaagc tgtattgatc agtacagtcg
    55861 cttctttctt cggtgggtta gctgcgatta tccatatgta tatcgtcgga cgcagaaaag
    55921 acttcttcga acttaaagat tttttgattt ccagccgtta tttcgaaaga gaaaaccgat
    55981 ctgcctctgt ctctatcatt cgggaaacac taccgtttat ttttgtcggc tcagtcatta
    56041 ctatcgttca aatgatcgac caagtaacga tgaaaccact gcttcacttt ttccgtccag
    56101 agatcgcaga tcagcaactg gaattcttat tcagccgtgc ttctgtcaat ccaaataaat
    56161 tgacattgat cctgatctcc atggtaggaa cagtagctat aagcagcttg ccaatattaa
    56221 gcacgatgaa gaaaaaagat cggatacaaa tcgaaaaaac agtaggagat agtttttcga
    56281 ttgcgttatt gattcttctt ccttcattga ctggaatgtc tttattagct ggaccactat
    56341 acacattgtt ttttggctat gatcctgaaa gtgtcggata tttccaaatg gctttgctag
    56401 cttctttgtt tttctcttta ttcacgatcc tatctacgat gcttcaatct ttgaatcacc
    56461 atcgttttgc gatccgatta actgtagaag caattatcct gaaagtcatc ttccaagtaa
    56521 tcggattagg attagttggc ggatacggga tgagcttatc aaatggctta gcattcggta
    56581 ttgtctttgt tcgcggctat cactttatgt gcaaagaata ccgaatagca cctttagcaa
    56641 agatcagcaa ttttttctta aaaactttcc gctccaccct gattatgctt gcagtatgtt
    56701 ttgccgtttt ctttttgctg aatcagcgat tgtcaatgga atcaaaaagc tatgcaatga
    56761 tttattgtgt ggctgtagga agtattggcg gcttagtatt tttattttct caattcggaa
    56821 aaaatgggtt tcgaatgttg aaaaatgtta aacatcatag cagaagcaaa gaataggtta
    56881 actaatcgtt ttttgctgtc acttgaaaaa cggcaactcg tatgattacg cttgtcgttt
    56941 ttctattttc caattttagt ttcatatcta atcttactta tgatatagtt ataaggtctg
    57001 gaaaaattct ttgaaacgag gaaattaaac acatgaaact tgcagtagtt acagatagtt
    57061 cggcatatct gccggaacgt atcaagaacc atcccgactt attcgttatt ccaatccctt
    57121 tgattatgga tgggaaaatt tataacgaag gaatcgatat cgaagcggat gaatattatg
    57181 gacttttaaa aaacagtaaa gattttccta ctacttcaca acctgtcgta ggggaagttt
    57241 tgggtttata tgaggaattg aaagagaaag ggtatgacac gattttaagt atccatcttt
    57301 cttcagggat ttctggcttt gtcaacacat tatttgcgat gaaagatgac atcagcggag
    57361 taacggtcat tccttatgac tctaagatca ctagtatgcc gatgggacac atggtagaag
    57421 ctgccttaga cttaaatgat gaaggtcagt cccttgatga aatacttgca catatcgatc
    57481 gaatccgaga taatacctat gcttatctga ttgtagatga tttgaacaat ttagtacgag
    57541 gaggacgttt gacaaatggt gcagcgctga ttggcagctt attaaaaatc aaaccgatcc
    57601 tgacattttc tgaagggaaa attgttttat tcgaaaaaat ccgttcaagt aaaaaagcat
    57661 ttgctcgagc tgaagaaatt attggtagaa gaaataacga aatacaaccg ccagtcaaac
    57721 tttacgtgat acatgcaaat aatttagaag tagcgattgc ggagaaagag aaattgcaga
    57781 aaaaatatcc aaatgcagaa atcgaaattg gtcatttcgg accagtcatt ggtacacatt
    57841 taggtgaaaa agccatcggc attgccattt cagcgcaata attcctttta ttcaaaaaac
    57901 ataccaaaaa tat
//
LOCUS       DAIGUC010000012        57673 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.012, whole genome shotgun sequence.
ACCESSION   DAIGUC010000012 DAIGUC010000000
VERSION     DAIGUC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.012"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(61..2424)
                     /locus_tag="NOB46_000728"
     CDS             complement(61..2424)
                     /locus_tag="NOB46_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HCI1057692.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="NOB46_000729"
     CDS             2872..3093
                     /locus_tag="NOB46_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1057693.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="NOB46_000730"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="NOB46_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCI1057694.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="NOB46_000731"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="NOB46_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCI1057695.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="NOB46_000732"
     CDS             complement(5894..6205)
                     /locus_tag="NOB46_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HCI1057696.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="NOB46_000733"
     CDS             complement(6202..6495)
                     /locus_tag="NOB46_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCI1057697.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="NOB46_000734"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="NOB46_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCI1057698.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="NOB46_000735"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="NOB46_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCI1057699.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="NOB46_000736"
     CDS             complement(8333..12685)
                     /locus_tag="NOB46_000736"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCI1057700.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GNTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="NOB46_000737"
     CDS             complement(12897..14606)
                     /locus_tag="NOB46_000737"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCI1057701.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="NOB46_000738"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="NOB46_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCI1057702.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="NOB46_000739"
     CDS             complement(16103..16903)
                     /locus_tag="NOB46_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCI1057703.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="NOB46_000740"
     CDS             complement(16900..17712)
                     /locus_tag="NOB46_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCI1057704.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="NOB46_000741"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="NOB46_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCI1057705.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="NOB46_000742"
     CDS             complement(18467..19189)
                     /locus_tag="NOB46_000742"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCI1057706.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="NOB46_000743"
     CDS             complement(19325..20206)
                     /locus_tag="NOB46_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCI1057707.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="NOB46_000744"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="NOB46_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCI1057708.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="NOB46_000745"
     CDS             21446..21925
                     /locus_tag="NOB46_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HCI1057709.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="NOB46_000746"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="NOB46_000746"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCI1057710.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /locus_tag="NOB46_000747"
     CDS             23226..24011
                     /locus_tag="NOB46_000747"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCI1057711.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="NOB46_000748"
     CDS             complement(24357..26048)
                     /locus_tag="NOB46_000748"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCI1057712.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="NOB46_000749"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="NOB46_000749"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCI1057713.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="NOB46_000750"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="NOB46_000750"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCI1057714.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="NOB46_000751"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="NOB46_000751"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCI1057715.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="NOB46_000752"
     CDS             30332..31033
                     /locus_tag="NOB46_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI1057716.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="NOB46_000753"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="NOB46_000753"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCI1057717.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="NOB46_000754"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="NOB46_000754"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI1057718.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="NOB46_000755"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="NOB46_000755"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI1057719.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="NOB46_000756"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="NOB46_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCI1057720.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="NOB46_000757"
     CDS             complement(34528..35508)
                     /locus_tag="NOB46_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1057721.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="NOB46_000758"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="NOB46_000758"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HCI1057722.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="NOB46_000759"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="NOB46_000759"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCI1057723.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38265..38432
                     /locus_tag="NOB46_000760"
     CDS             38265..38432
                     /locus_tag="NOB46_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HCI1057724.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38494..40305)
                     /locus_tag="NOB46_000761"
     CDS             complement(38494..40305)
                     /locus_tag="NOB46_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HCI1057725.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40302..40667)
                     /locus_tag="NOB46_000762"
     CDS             complement(40302..40667)
                     /locus_tag="NOB46_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HCI1057726.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40830..41225)
                     /locus_tag="NOB46_000763"
     CDS             complement(40830..41225)
                     /locus_tag="NOB46_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI1057727.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41243..42205)
                     /locus_tag="NOB46_000764"
     CDS             complement(41243..42205)
                     /locus_tag="NOB46_000764"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HCI1057728.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42205..42417)
                     /locus_tag="NOB46_000765"
     CDS             complement(42205..42417)
                     /locus_tag="NOB46_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HCI1057729.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42438..43136)
                     /locus_tag="NOB46_000766"
     CDS             complement(42438..43136)
                     /locus_tag="NOB46_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCI1057730.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43156..43698)
                     /locus_tag="NOB46_000767"
     CDS             complement(43156..43698)
                     /locus_tag="NOB46_000767"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCI1057731.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43830..44834)
                     /locus_tag="NOB46_000768"
     CDS             complement(43830..44834)
                     /locus_tag="NOB46_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI1057732.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44831..45820)
                     /locus_tag="NOB46_000769"
     CDS             complement(44831..45820)
                     /locus_tag="NOB46_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI1057733.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45817..46623)
                     /locus_tag="NOB46_000770"
     CDS             complement(45817..46623)
                     /locus_tag="NOB46_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057734.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46789..47745
                     /locus_tag="NOB46_000771"
     CDS             46789..47745
                     /locus_tag="NOB46_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1057735.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47822..48340)
                     /locus_tag="NOB46_000772"
     CDS             complement(47822..48340)
                     /locus_tag="NOB46_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI1057736.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48428..48577)
                     /gene="rpmG"
                     /locus_tag="NOB46_000773"
     CDS             complement(48428..48577)
                     /gene="rpmG"
                     /locus_tag="NOB46_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI1057737.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48805..49251
                     /locus_tag="NOB46_000774"
     CDS             48805..49251
                     /locus_tag="NOB46_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCI1057738.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49446..51341)
                     /gene="asnB"
                     /locus_tag="NOB46_000775"
     CDS             complement(49446..51341)
                     /gene="asnB"
                     /locus_tag="NOB46_000775"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCI1057739.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51666..52640)
                     /gene="bsh"
                     /locus_tag="NOB46_000776"
     CDS             complement(51666..52640)
                     /gene="bsh"
                     /locus_tag="NOB46_000776"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI1057740.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(52974..53061)
                     /locus_tag="NOB46_000777"
     tRNA            complement(52974..53061)
                     /locus_tag="NOB46_000777"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53027..53029),aa:Ser,seq:cga)
     gene            complement(53206..53772)
                     /locus_tag="NOB46_000778"
     CDS             complement(53206..53772)
                     /locus_tag="NOB46_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1057741.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54028..55359
                     /locus_tag="NOB46_000779"
     CDS             54028..55359
                     /locus_tag="NOB46_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HCI1057742.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAAFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55325..55675
                     /locus_tag="NOB46_000780"
     CDS             55325..55675
                     /locus_tag="NOB46_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057743.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55767..56186)
                     /locus_tag="NOB46_000781"
                     /pseudo
     CDS             complement(55767..56186)
                     /locus_tag="NOB46_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(56187..56531)
                     /locus_tag="NOB46_000782"
     CDS             complement(56187..56531)
                     /locus_tag="NOB46_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCI1057744.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            56797..>57673
                     /locus_tag="NOB46_000783"
     CDS             56797..>57673
                     /locus_tag="NOB46_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1057745.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNI"
BASE COUNT        16274 a        12169 c        10080 g        19150 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtattac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 tccattttcc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagcg agggcgttac
    34681 atatttcgct acactgacat cattgaagcc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aagtgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgccggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct aggcgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat cgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccatttt tccaatactg agttagctgc ttcaataagc
    36061 aagtttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatcttc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaattggt
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg ggaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taatcgcttt gatatctgtg tattcaggtt tccagcccag aatctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaaggctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tctttcggct ctccataagt tgctgcagta gaagagaata
    37681 cgattttatt cacgttgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattct atataattta aaaaacgaag tttactttta tggtgaaaac
    38101 aaacaaagta aaatttcgta aattcatatg gtaaatttat aataaaacat ttagtaaaca
    38161 ttttcaagga ttttttgcaa aggtttacaa acaaacgtaa aactagcctt tttttctctt
    38221 ttgttccata atagatataa caaataataa atgaggtgga ttcaatgaaa aaatttgtat
    38281 ctggaatatt agtaggaagt ctggcaacag ccgctgccgt tgctggtttg gttgcttctg
    38341 tgaaaaaaac agtgatcgat ccaattgacg aaaaagaagc aatgatcgaa gaaaaccgta
    38401 aaaaagcaat gcgtaaacgc gtttctcgtt aataattatt taaaaatacg catgaagact
    38461 ttctaaaaaa cagataagtc atcatgcgta tttttatttg tcagtcaata taagttgtgc
    38521 tattttatct gcctgtctca gattccatgg atctgtataa ggtctagcta ctgctgcagt
    38581 tagccaatcc acaccttcaa caggtattcc atagcaataa aagtcagact ggatttcccc
    38641 tgaagcatca atcacgcgat tcgtacctcg ctcaacatct atagcttctg aatgataact
    38701 tcctgtatta tctgaaaatg aaaaagggcg aacaagtttg ttttccttca aattttttat
    38761 gacaggatta cttgaacgag aaaagcttgt ttgtggcaat cgagcttcaa tcaaatagcg
    38821 actgctgatt tctttatctt gtagagaaat aacatagcgg ttgtgctttt gctgaatatc
    38881 aaatggcggt tcgatcaaat gaaaaatacc cgcatctatc agtgctgcta attctttcgt
    38941 ccgaatgatt ggcggaccga tcgttaaaaa gctatttaga tgagtaaacc atccccatag
    39001 tatttctttg tattccttag cagaaaaaac gtgccattca atagcctgcc ggattggatc
    39061 acgccagtct tttaatgcat caaatgttga agcaaatgct cctgtgcaat tgcctttttc
    39121 cgcttctttt atctgccctt caataaatat tcggctagct tctgaaaagg gctcattctg
    39181 ataggcaaga ggagtttcta aatacgacca atcccatcta taagggatta gtgctggatg
    39241 ctttccgaga cactcctctg aagagaggga gagaaaatca tgctcaaaat ttttctttgg
    39301 aatcggcaag tgatattctt cgatgatttt cttgtaataa aacaactcaa cgtctttttt
    39361 cagatagtca aaaaatgttt cgccagtcaa aaatcccgac tgatgccatt gctccaggtt
    39421 ttcttttgtt agtaaccgtg gccatgccat tgctccgcct tgcttttgat ttcttcctcg
    39481 agggtaataa gggagccccc ttcttgatcc actgtataca atcggttcct tgcctgatgg
    39541 atgatagacc agttttccct tttcgttctc gaagcgccct cctcttgata ctgtaaacaa
    39601 tccgacataa tcaaaaaaac ttaagcctag acctcttaaa aagacatttt ctttaggcgg
    39661 tatcttcgaa agatctacat ctgcaggatt agaaggaagc tgatacagta aaacattttt
    39721 ctttgcgtag tctacccaca ctctttcttc ttctgtctca tcattttccc agtgaccgct
    39781 tgctaaaaca agctgatcga tagaatagct ttgctgatct gtctgtaaaa gataaccatc
    39841 ttttcttttg cttacttttt ttactaaaga ataaacaaac tgaatagaag ctggaaattc
    39901 ttcttgcaac tttgagaaaa accagcgttg atagagtccg tataaacatc gagtagattg
    39961 ctgatctttt tccagacgat tgatttcttc tataattagt tgcttatttt tggttaccgt
    40021 ctgttcgata taatctgtag caggtccttt actccattga aacaagttgg gtccctgtgt
    40081 taccaatcct ccactggaca atgtttcatc tgtaaaaagc gtcacttgtt gagaaacaga
    40141 attcattaat aactccggtg gctgattcaa ccgccaaact cgacctccag gaccattggg
    40201 atcgaaaaga aaaagttcaa gagaatgtct gtcctgatta ttatggagaa tcctttctgc
    40261 tacacttaat cctctaggtc cggcaccaat gatccctatt ttcatttgca tgcctccatt
    40321 tcgataaatt ttttcaataa aacagcatgg ttctgatgtt cattttttgc accataaaca
    40381 aaagtaatga ctggatgttc tttcataagt tgactgagtt taaaaatagc ttgcttcttt
    40441 tcttcttcga aaatcaattc ttgctggtat ttctttgcaa atgaagcaaa tcgttctggt
    40501 acatggtcaa aagttttgcg tgcttcatta ctaggtgcaa tttctttcaa ccacagatct
    40561 aactgcgctt tttcttttga aattcctcgt ggccagaatc tatccacgag tattctatag
    40621 ccatcctctt tttcagcatc aaggtaaaca cgttttaatt tgatcatagt tgtttccttc
    40681 tttctacctt ttcgcttagc ttatatatgt agataatagc acaaaataaa aaaaatgaac
    40741 ggcacaacta tccattgcgc cgttcatgtg atcttggtca aaatctaatg attgattcgg
    40801 tttttaaagc tgtcatacaa tcatctgttt tatacttttt tacttttgat ttttccagac
    40861 catccgtcat atccaccctt aagtaaataa atctcttgat aacctgcttt acgtaattta
    40921 tttgctgtac ggatgctcaa acttttcttt tgatcgtaaa tatagacagg ctggtctttt
    40981 cgaatagatc ctaatgaatc tttcaaaaca gtgtaaggga tgtttcttgc acctaaaata
    41041 tgcccagcat caaacacatc tttttcgcga acatcgatta cttgtgcttt tctcattcct
    41101 tctcgaaatt cttcttctgt caaagtcgtt gctgaacgtt tggccattac tcgtagatag
    41161 acttcccaaa ggatgattgc aagcacaatc aatagcaaaa tgatattaat tacccataaa
    41221 accatgtaat gcctccgttt ttttaagcaa atttcaaggc taatgaggca gcaccaatga
    41281 caccagcttc attaccaagc tctgctaatt tgatttttgt tgattctctt acttgcggga
    41341 aagtaaattc tttaaaatat ttctctacac ggctacgtaa aaattctcct gctgccgata
    41401 ctcctccacc taacacgata cttgacggat ttaatgtatt ccccaagttt ccgcaagcta
    41461 aacctaagta gaagcatacg cgatcaacaa ccatcaatgc aaacggatcg tcttcttgag
    41521 ccatttcaaa gatatcttta cttgttactt cttctccgtt gtctagcatt gctttcagtt
    41581 ttgaatcccc tgcgtattct tctgccaaga aacgacctag gcgtaccaca cctgtagcgc
    41641 tagatacagt ttctaaacat ccgcgtttac cgcaagtaca ttcgaaccct tcaggatcca
    41701 cagtgatatg tccgatttct cctccagctc cgctcacgcc gtgaatcaaa tttccgccag
    41761 caacgatacc tccgccaaca cctgttccta gagtaacgaa tacaacgtct ggatcgtttt
    41821 ctccagcacc tttccatcgt tcacctaaag cagcaacatt cgcgtcatta tcgatagcga
    41881 atttgattcc tgttcctgcc tcgatcagtt ttttcacaaa ttgaacttct gtccagttta
    41941 agttatacgc accaataacc gttccagctt cgctgtccac gcttcctggg gtacccatgc
    42001 cgattccgat aaagtcttcg gctttcatat tatataaatt caaacgatga ttgattgatt
    42061 caatgatttc aggaacgata tgcttaccat catccaaaat attggtatcg atgctccatt
    42121 tttgctgaat ctctccttct ggtgttaaaa ttgcaaattt tgctgttgtt ccacctaaat
    42181 caatcccaat aatcttcttg tccattacaa atttcctttc tttcggcttt cttcaattcg
    42241 gtgctctctt tttaatatgc gccacgctgt catgtatgta tcatgatcaa tcaaacggct
    42301 atcatacaga ttacgcaatt cgatagtcat taattcaatg tcatagatgc gtgcacccac
    42361 atagataaag atgccaaatt ttttgaacag ctgctgtaca tcatataagc tctccatctt
    42421 taagcacttc cttcatatta tacaagtaaa ccatattttt ttaaacccag taaaatacat
    42481 attacaaaaa gaaatacaaa aactagtgta gaaagaatcc tttggtgtat cgaatagctt
    42541 gtctgttgtt tcggtagacc caaaacattc cctaacacta atccgccaat tagcccaccg
    42601 acatgtcccc aaacatctac agaggtatcc agaagaccaa aaacaaatgt caacacaata
    42661 aataaaagaa aatgtctgac tagctgctgg atcgctgggt tatgtttaaa atgaaaccct
    42721 aagataaaca acgcaccgaa caaaccgaat atcgaagtac ttgcaccacc agacagaaca
    42781 ttcgcttcgt taaaagcaaa gcttgctgta tttcccatta tcccgctgaa catataaatc
    42841 aagaaaaaac gccaatggcc atagattgcc tcgatttgct gccccataaa atacagtatc
    42901 agtgagttca ttacgaaatg catcagtcca aaatggatga agattggtgt cactaaacgc
    42961 caccattcat tgaagtgaac aagataagga ccatacattc cggcataata agggatctca
    43021 agtcgcggaa ataattccat catgaggaag accgctgtct gtatccctaa aaaagcatag
    43081 gtccataacg gtcgtcttaa ccatgcacgc aattttattt gctgttgata attcatgaaa
    43141 acctcccatt tcattttagt caataaacaa ttgttggatc ttctgatcaa agctctccgg
    43201 ttgccattgt tcattcaatt gttcacgaaa aacaaggcta catgtttttt tatgaaaatt
    43261 atttaaatac cggtcgtaat aaccaccgcc aaaaccgatt cgataaccgg ctctattgta
    43321 gataatacct ggtacaatga ggagatcgat catctccggc aaatagagct tctctgattg
    43381 tggctcaaga acaccaaaac tcgaacgtac aagaacggac tgttcatcca tttcataaaa
    43441 cgccatctga cgtttcggca aagttttagg tacaactatt ttcttttgtt ctttttctgc
    43501 tcgttggata accggctgtg tatccagttc aaattcattc gataaagtcg tccctatcac
    43561 ttttgctgac ttccagtact cgctggcgaa tagctgttta tagattcgct gttctttttc
    43621 ctttttcttg ccacttttgg ccagattttt cagcttttcg attcctttcc ggcgtaatct
    43681 tactttcaat tggtccaaaa actcaccctt ccttctctca taaaatggta taggaaaaaa
    43741 agaaaaatag caatcgaact ttcaaataaa tgcataaata gaataaaaag aagacctaga
    43801 aatgattggc cttccttttt taatgaattt caactgttca gcgcgtgttt ttgtctgata
    43861 aaaagtgcat acagaaaata tggcgcacca aaaagggcaa tcaaaattcc tgtaggtact
    43921 tccccactta gtagaatcac tctagcaacc atatctgcac taagcagaaa aatggaaccg
    43981 aacaaaccgc tcagaacaaa ggtccagtta ttttctttac gtacgactag cttcgcagca
    44041 tgaggagcta gtagtcctac aaaagataaa ctacctgtca ccgctacact accgcttgcc
    44101 aaagcaacag ctaacaacaa aaggattttt tgacttttag ccacgttaag gcctaatcct
    44161 tgcgcgcgtt cttgaccaaa tgatagcaat acaatcctct gtgcataaag tcctcctagc
    44221 ggaattaaga taaccgccca tggaagcaat gcccaaacat aaggccagct cgcaccccag
    44281 attgatcccg ctaaccatgc attcacaaat ccataatttt ccttagataa ttggatcgtg
    44341 catagcaatg ttaatgcaga aaggccggca ttaacggcaa taccggacaa taagattcga
    44401 ttcataccca aaaagccatt tcgatcatag gccgcaagat agacacagca agcagctaaa
    44461 acaccaccta gaaaggctac aactagcaat agaaacggca gcgaatagtg cgaaaagaaa
    44521 cctaaataaa gcatcactaa aaatcctgct ccggcattaa tgcccaatat actagaatct
    44581 gccaattcat ttcttgttac tccttgcaag atataaccag aaacgccaag acaagctcca
    44641 gctaataaac tgatcagtaa tcgaggaact cgaaattctc taacaatcag cgccaaagaa
    44701 gatgattctt tccctatgaa cgtggcaaaa agctgatcca ggtaaataaa aggcgtacca
    44761 atcattaaac tacctataga caggatgaca agtacaaaaa gcaagaaata gaacgtccaa
    44821 tatatttttt tcaccgttgt tccctcctta cttgtatcag taaaaacgga acgccaatca
    44881 atgcaatgac taatccaaaa ggtgtttcaa aagggggatt gatcatcctc gctgtaaaat
    44941 ccgccaacat aaccaatcca ccgccaacta aaaaagagac aggtagaaca taacgatagt
    45001 ccgttccaac cattccgcga acaactggcg gaaccaacag cccaataaat gaaacaggtc
    45061 cgactaacga aacggcaatg gctgctaaca ctgcaactag acagaaaaca atcaaccgcg
    45121 ttcgtttagg atgacttcca agagctaatg catgtgtttc actcaaatga atcaaagata
    45181 ttgcttttcc taatgaaaaa gaaaccaaaa cagcaagtat atataaagga aacaatactg
    45241 ctaattgttt ccatgtgata ttggcagctc cgcctacaaa ccaaaaagca agatcctgct
    45301 gcagattaaa gaattgggta agtgcttggc tgatagcagt aaaaaaagaa ctaatagcta
    45361 cgccagctaa aatcagctgt aaaggattca tgcccatttt cgaaaactgc aaaaaaccaa
    45421 atacgagcaa agttacagca aaagaacctg ccaatgacat tagaaacaca gaaaaatcag
    45481 aagctttagg ccaaaaagca aaactaaggg ccattgccaa cgaagcaccc gcgttgattc
    45541 ctagtaagcc tgaatctgct aaaggatttc ttgtcactcc ttgcatcaat gcaccgctca
    45601 atgcaaaaca actccctaca agaaatgctc ccgccacacg aggcaaacga atatttcgta
    45661 tgatttggtg actttgtttt gatctatcaa aatcaaacaa cgcctgccaa aaatctgctt
    45721 ttcccacagt cgctgcgcca tttgaaagag caacaaaaaa aataatcaaa agaacaaaac
    45781 agaccaaaag caggagtcta tttttcttca tagtcctcat aattgatcct cctgctcttt
    45841 tggcaacaaa tcataggtta gaaaaactgg tttatttgtt cttggaagcg tgacaatcgt
    45901 tgcatcaatc tcaaatattt ttttcataca ctcttttgtg atcacttctt caggtgtacc
    45961 ttctgtgatc aacttaccgt ttttcattgc taataaataa tctgaaaaac gtgaagcatg
    46021 attaatgtca tgaatcgaca tcaagatcgt tgtttgtttc atttgattga tttcagtcaa
    46081 taactgtagg atctctaatt ggtgtgccgg atctaaaaat gttgtcggtt catccaagat
    46141 caagatatct gtttcctgag caagcgccat agcgatccag acacgctggg tttgtccacc
    46201 agacagcgtt gcgatatccc gcatacgaaa tccagctaga cctgtagcat ccaacgccca
    46261 ctcaattgct tcatgatctt gcgtgtccat gccactgaac agtttttgat aagggtatcg
    46321 tccgtaagat actacttctt ctactgtcat acctgtaggg tgttcactag tttgtgctaa
    46381 taatgcaatt ttttttgcaa gttcttttga actgtatgta gagatatcag agttattgac
    46441 aatgatcttt cctgatttca caggtagtat acgggtaaaa cttttcaata aagtagattt
    46501 tccacttcca tttggcccaa tcaaactagt gattttccct tcaggaatcg taacagacat
    46561 gttttcaatg atttttttgt tttcgtagcc ggctgcaatg tcagctgctc ttaatctcgt
    46621 catttcaccc atcctttcgc tgaaaatcat tctcaattat gacgctgttt caacatttcg
    46681 tcaagcgcta ctttcatatc tatagccaaa tgaagcggtt gacagcgttc gaaatatcag
    46741 gaataataac caatgagaaa gattctcaat tatgttagga ggaaagaaat gaaattaaaa
    46801 acaaaagtat tcacattatc tagcatattg ctgctggctg gagtactgag cgcttgctcc
    46861 ccctcttcag ataaagaaac agctacaact gccaattcga cgacttcatc caatagtact
    46921 catacagtca cagatacact tggacataaa gtagagattc caaacgcgcc caaacggatc
    46981 atcggcagtt acttagaaga ctatctgatt gcactagggg aaaaacctat cgcccagtgg
    47041 actgttggca gtggttccat tcaagattat ctgcaagatg atttaaagga tgtcccaacg
    47101 atttcttatg accttcctta tgagaaagtg ttaagctttg agcctgattt gctgttgatt
    47161 tcttcttccg ctactgtcga aggcgggaaa tacgaacaat atagcaaaat cgcgccaact
    47221 tatgttgtaa aaaacggaac agatgtcaca tgggaagaac aactaaaaga tgtcggcaaa
    47281 gctttggcaa aagaaaaaga ggcagaaaaa atcatttccg attatcaaaa atccatcaag
    47341 aaaactcgag aagaactagc agataaaatc gagaacaaga cagctgcagt gttgtgggtg
    47401 accaacaact cagcctttat ggtcagcaaa aatcggtcaa gtggaagaat cgtatacgac
    47461 gatctggaat ttggtgttcc tgatctagtg gaagaggtct ccaaaaaagc cacttctgac
    47521 tggtctgctg tttcctctga aaagctagct gaattagatg ctgactacat catccttgtg
    47581 aacagtgaca aagatgctgc catgttcaat gaaccaagct ggaagaatct aaaagcagtg
    47641 acagacaatc atgtactgca attcggacct gaatctagtt ggctatataa cggacctatt
    47701 gccagtcagg aaatggtcaa tgatatcaaa gaaaaactaa attgatttta actaaaaaaa
    47761 gcatcttcac gattagtcgt gagatgcttt ttttcttatt aacaaactag acgcatagat
    47821 tttattcttc ttttgaagca accctatttt ttactctttc ccatttttga aaacgatggg
    47881 catatagatt ttcttgatcc gttatcccct catactcctc tataagggcg aagtctgaaa
    47941 aatcaatatt cccaatatac gtatcgcctt caaacgtgct atcgatcaat gttcgccaga
    48001 tccgaccagt gtaaggaaga agttcttgaa aaatccgact accacccgaa acatagatat
    48061 cttctgagat cgtttgacta tacgacaaaa gttcatcgat cgaatgcatt acttccgcat
    48121 tttctttcgt gcgaaaattt ggttgcgttg tcaacacgat gatatggcga taaggaagtg
    48181 aaagatcccc cattccttca taggtctttc ttcccatcac taaaattcga tccattgtgt
    48241 gttcgcgaaa gaaacgcata tcatttggca atcgccatgg taacaaacca tttttgccga
    48301 tcagaccatt tttatcttgt gcccacatgg aaataaacat attatccgct ccttatgatt
    48361 ttagatgttt tgagataaaa aaagtctcaa ttctttgacc agcaaggaat tgagaacttt
    48421 aaaaacatta ttttgtttca cggtgcaaag taactttgcg ttcgcgtggg caatattttt
    48481 gtttttccaa acgatcagga ttgttacgtt tgtttttgct tgttagatag ttacgttctt
    48541 tacaagaagt acactctaaa gtgatgttta cgcgcatgtt tttccctccc atttttacaa
    48601 gaatcctcta agatgactct cagacttgat tatcttacca tgattttttc tagattgcta
    48661 gtgtttttca cgattttgtt aagtaaaact acttgacgat aaatacaacg gttttacttc
    48721 tcaaacaaaa tctttttctt tttgtataaa tacccttaca cttgtttata tagattatgt
    48781 tttttaataa agggggatac taatatgcca tggaacatga aggactttcc tgcatcaatg
    48841 aaaaacttag ataaattgac aagaaaaaaa gcaatcgaca tcgcaaatgc attattagat
    48901 gaagggtacc ctgataaccg tgcgatccca attgccattg atcaagcaaa aaaatggtat
    48961 gaagatgcta gtgaatcaga aaaacgaact ttcgaaaaag aaaaaaatcc aagcaagacg
    49021 gatgaacacg atacgaatcc tcgtgctgga aaactgcttg attcagatgt gatcgtagaa
    49081 tatgaggaag aacaatggat cgtgaaatct aaaggggcaa aaaaggcaag caaccatttt
    49141 gatacaaaaa aagaagcaat cgaaaaagga aagcaagtag cacaaaacaa agaatcaact
    49201 ttgttcattt ataaaaaaga tgggacaaaa gaaaaagaaa tcgattattg aacatatgta
    49261 aaggggttgt gacgaaaatc gtgtcacaac ccccttatgt tcgaaacaat ggtgttcctc
    49321 tgccaactcc gaaccataag tcataatatc tataaaacgg gaagagctgt tttttgaaat
    49381 tgtttcttat cactcagtgt taaacggtag gagaaaacct cttttttatt gatatttgat
    49441 tttcatcaaa cagtcacata gtcgattgct tctgcttgcg gaatcgtttc atctacaaag
    49501 tagactttat accatgtcaa gaaactgaag attgtccaga tttttctttg ctcttcttta
    49561 cgtccttcgt gatggtcatc tagcaacttc atgatttttt cttgatcaaa aaattctttt
    49621 gcaaaatctg cttcgaataa tgctttgact tgttcgtagc cgtgttcttc tttcaaccaa
    49681 gctttgattg gcacagggaa tcctaatttc acacgattcg accattcttc cggaagatgt
    49741 ttgttcgcag cttgtctgaa aatatctttt gtgttgtttt gattcaataa aaacttactt
    49801 ggtatttgtt gagccaattt catgacttcg atatccaata aaggtactcg gacttccaaa
    49861 gaacttgcca tagaaagttt atctgccttt aacaagatat cttttggcat ccattgatga
    49921 agatcgacat attgcatctt attgacttca tctttgattc cttctgtttt ctcgtaatga
    49981 acagtcatga tttcatccac agatggtgct gtttgatatt ttggtgttaa cacttctgat
    50041 gcttctgatt cttcgaacac tcgagcatga ccgataaaat attcttttgc aggagcaagt
    50101 gattcatata aatggatccg tccatggaaa tttttcattt ttccgatttt acgtcctaaa
    50161 ttatagcgtg ttccttttgg taattttttc aatccttgag caatcacacg gatgaatttt
    50221 gaattcgtat ggaatccata cgtttggtat cccgcaaaca gttcatccgc cccttctcca
    50281 gattggacta cccgcacact ttgtgaagca agatttgcta aaaagtacaa aggtacgcaa
    50341 gaaggatttg aatcaggttc atctaagtga tactggatca aagggaatgc tttgaacgac
    50401 atgtctccgt cgatcactgc tgctgtatta tctaagtcca atagttcggt tagttttctg
    50461 gcttcaatcg cttcattata ggttttatca tcaaacccga ttgagaaaga atgatctggt
    50521 ttcaatacag aggttacata actggaatca accccgctgg ataagaaaga accaacttct
    50581 acatcactga ccgtatgtgc ttcaatagaa gcttgaacgg tttcgtcgat tttttcgatc
    50641 cattcttgtc gggaatgcgt ttcttttgtt tcaaaatctg catcccaata ttgctgaatg
    50701 tctatttttc catctttata cgtataataa tggccttcag gcaaacgata gacatctttg
    50761 aagaatgttt cgccgtttaa tggagaatat tggaaagtca tataaggttt caacgcttct
    50821 ttgttcaatt ctttgttaaa atcaggatga ggcagaaaac ttttgatttc tgaaccaaac
    50881 ataaatgttc cgttcatttc tgcataataa tatggtttga tcccaaagtg gtctcttgca
    50941 ccgaataact cattcttttc attatcccaa atagcaaaag caaacattcc gcggatcttt
    51001 tgcaataatt ctgttcccca ttcttcgtaa ccatgcaaaa ggacttctgt atctgcatgt
    51061 gtttgaaaaa cgtggccagc tgcaatcaat tcttctctca aaggctggta attatagatt
    51121 tcgccattaa aaataatgat ctttgtccga tcttcattgt aaataggctg agtaccgccc
    51181 tctaagtcaa taatacttaa tcttctgaat cctaaagcaa catgtttatc gatatattct
    51241 cctgaactat taggtccacg gtgaacgatt cgatccatca ttgtattaat aattgttttt
    51301 ttgttgtcct tgtcgttaac aaaacctaca ataccgcaca tttaactttc acatcctaat
    51361 ataaaattac tgtttatttc attcatatgc atcttatcat agaataaata gcggacgaat
    51421 attttctctc ttacaatttc gtcacgtgaa aacaaaagat gaaagtttct gtttttacag
    51481 aaaataaagt cccaatatct aatttaccat gttttctttt ttgaggctac cttattctct
    51541 tcgtgttaaa aaaatattag tggatgctat ttccaaaaaa accagcaaaa aaagacacga
    51601 cctaaagatc gtgtctaatt atgactgtat cagaaaatat gataccaaac ggatctattc
    51661 attaattaat tgacatagtt tatctgttgc tcttttatga ctggataact gaccaattca
    51721 tgacgatcca agtcttcttt attcatattt acagcagtaa tttgactgtc ttcatacgta
    51781 cgataataat aaatcccttt atcaacgtta cagcaagaag aataaatcgt atattcgtat
    51841 tttctttctc cagtatcgca tactcctttt tgttgctcga ctgagcctag tatatgaaaa
    51901 aattgactga tactttcaga ttctgaatca cctgatgcag cattcatttt agtaaatgtg
    51961 gcttttacaa atcgagaaac agaagagaga tctccaggta agcccaatcc tcccatccca
    52021 cgactataaa cattcaagct gatctggttt gaaaaatgat tttctggtgt tccatttgat
    52081 agcgagcgat aattgttcag attaaataat tgataatcaa atggcggatt atttgtcaac
    52141 acaccgacag gattatcata taaatgaagt ccatctttca tactttcaat tactatcgat
    52201 ttttctttat cagctaataa ccagtgtaaa ggtgacaagg gtagtttttc actaaaatcg
    52261 atattgacta gattgatagt agccaataat tctttagctt cgtctatggt tgagcattgc
    52321 cctagtatcc atggaataaa ctcaaatggt gcaacgttat cttttccttc ttgtaattct
    52381 ttataatcag cattgccagg aaaattcagt cctgccatac tcaacccttt ttcatttgta
    52441 gcctcataat agagtggata gttggatacc ccagctgcta ttcctatcat tgcataatgt
    52501 ttatctaaat tttttacctt tctaaaatcg aaacgataat ttcttggagt aatagtgacc
    52561 acttcattat aagacatctc ataatcaaaa ttccttccaa aataatggtc tttcgttgca
    52621 taagtgattg cggtacacat cgtttcccgt cctaaaacaa atcgttttta cacttttatc
    52681 ttacatctag tatttttttt atcaaaaaaa ggccaaagaa gattgattta ctagcattta
    52741 taaaaaatag tactcagggg gaatcaaaaa atattgtagg ttaaaagtac aacaataagg
    52801 ggctgtgaca aaagtcttgt cacagcccct tattccgaac aaacggtgtt caaaagcttg
    52861 catctgcggt aataagccca atcaaacgaa aaaataggaa aagctatttt tgtttggccg
    52921 ttcttattac ttgatgcagg acagcttctt cacaacctct aatcgttgat ataaggaagg
    52981 tacaggattt gaacctgcgc gccggtatta gccggttcgc cggatttcga gtccggtgca
    53041 ttaccactct gccaaccttc cgtaagtact atttttaaac ttttttcacg aaatgtcaag
    53101 cctatttcta atagataaat aacagaaatc gcttttttta gcaaaaaagt ccattgacag
    53161 tttgcagcca acggacttac cgatcaaatt catactgata gaacactatc tgattatttc
    53221 aggattatct aatgctaaaa tcgagtcaat tgtccgtttg atcagtgcaa tgatttgttc
    53281 ttctgttgga tgcatgatgt ttgatgacat caatgacgct aagccagtca ctgctaccca
    53341 tgtaccagta tgcagagcat cgacatattc atccgataat tgattgtatc tttcatcttc
    53401 tttaactatt tcacggaaat aattgtatga aaaatcatgc attttctttc cgtccccatg
    53461 ttcatcaatg tacaatgcca tgtaaagact atgatgcttt tttgcaaagt agatatagtt
    53521 caaaccgaga tcaatgattt tatcaccagt acgttcaata gggaaaacat cttcttttag
    53581 ttgttcaaag atagaatcca gcaacgtatt ttttaaatct tccatgtttt tgaattccag
    53641 ataaatcggc tgtgtcgaaa tccccatctt tttagcaata tttctcgcag taaatccttt
    53701 aaacccttcc tttgcaacaa catcataagc agcttttaga atttgatcct tggtatagac
    53761 ttttcttctc attaaaactc ccccacttct ttactgcagt atatgttgtt ttattgtacc
    53821 ctatttttag cattttttgc aaacatttta ctcaaaacgt tatattttaa attttttttc
    53881 agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca atgggttccc
    53941 ttacattttt agttttgacc taaataatag ttgtccaaat ctttcatttc aagttatagt
    54001 taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat ttatattcat
    54061 cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt tacaggtgtt
    54121 ttttttcttt ttattggctt gctttctaat actcctactg ataattggag tggattgcta
    54181 actattctta cctcgccaag caatcttttg acagattatt ttgctttagg cggtttcgga
    54241 agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc ttatcggcac
    54301 aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg tttctctttt
    54361 tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct atacgctgca
    54421 tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag cgcattatca
    54481 ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg tattttattg
    54541 gggaatttag ctggcatagc aattggtcta cttcttccgc ccttagctgc tcaaacttta
    54601 gttttccatc gtggattcac actttataat attggattca cctctgggtt gattgcgatg
    54661 acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac attggttttc
    54721 aatgaatatc actttcctct catttggatt atttttggct ttttttcgct gacagtcgga
    54781 attggtttct attataattc ctttcggctt ttggggattc gagaaatttt cgattcatct
    54841 ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt gatcaacata
    54901 ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca gttaaatgga
    54961 cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg tcatttaaaa
    55021 aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac ttttcatgag
    55081 atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtctcgc gcccataagc
    55141 ggtttttacg gcagttttta cggtgtaata gctggtgtac tacatattgc tcttgtccat
    55201 aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc aactggtttc
    55261 gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa ggaaaaaaag
    55321 acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt atttatattc
    55381 ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc ttttcataga
    55441 gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg atttgctgaa
    55501 caatcctcgg gaccctagta tggaaatcta ttatcaagaa ctattaggta atccccgaca
    55561 tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa tcatgtatgc
    55621 ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt attaacccta
    55681 ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga ttaaaatcta
    55741 ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata cacttcatct
    55801 gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc aaaccaactg
    55861 tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac atctccagcc
    55921 attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc ggtcacaagt
    55981 aagatttgat agccgtcttt atggacatgc cagtgattgc gacaacctgg ttcaaaagtt
    56041 acattaccta caccaacaga aacttcggga tcattcacta acatattcag atagctttac
    56101 ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat cacgccattg
    56161 tgtatttctt cgtgttttgt cgtcatttac gcctctttct tatcttcgct attttcttct
    56221 aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccatcc tacataaaaa
    56281 gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg cttgccaatc
    56341 ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga tatggtgatg
    56401 atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa taaaacatca
    56461 tcattcaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc tgcggtttgt
    56521 ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac tatggttcta
    56581 aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc tttcagcctg
    56641 tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa cgcttttttt
    56701 attcgccgat tgtaaaatta agctagacaa ctaaaaaagt catttgtgct acactcaaaa
    56761 tagttccgtc caaagaatta taaggagtga gtacaaatga cctataccca tcttacaacg
    56821 gatgaacttg taatgataga gtcttatttc aaaataaatc aatctgttgc gaaaactgcg
    56881 catttcttga atcgttcaag acaaacgatc cataaagtat acctgttctt caagcaagga
    56941 aaatcagcct tagagtacta tcaacagtat aagaaaaaca aatcaaactg tggtagacgc
    57001 ccgcttgttt tacctgagga acaatcagaa tatattcaaa gaaaggttgt tcaaggatgg
    57061 acacccgatg tgattgttgg tcgtgcagcg tttcctattc gttgttctgc tcgtaccatt
    57121 tatcgtatgt tcaaaaaggg gctatttaat ccttctgact taccgatgaa aggcaagcgt
    57181 aaaccaaatg gacatcaaga aagacgtgga aaacaagctt tccgtcgctc tattcatgaa
    57241 cgtgaaaaag attatagcca attctcaaat gagtttggtc accttgaagg tgacactatc
    57301 gtaggtttga aacataaaag tgctgtaatt accttagttg agcgattatc aaaagttatc
    57361 atcacattga aaccgtgtgg tagacaagcg attgatattg aaaacaaatt aaatcattgg
    57421 tttgaatctg taccgaaaaa tctattcaaa tccatcactt ttgattgtgg aaaggaattt
    57481 tcaaattgga aacagatcag taatgccaat gatattgcca tttatttcgc tgatccagga
    57541 acgccgtctc aaagaggcct aaacgagaat tctaacggat tgttacgtag agatggttta
    57601 ttgaaatcta tggatttcaa ttcagtagat gaatttttta ttcaatctgt cgcatctaaa
    57661 cgaaataata ttc
//
LOCUS       DAIGUC010000013        56388 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.013, whole genome shotgun sequence.
ACCESSION   DAIGUC010000013 DAIGUC010000000
VERSION     DAIGUC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.013"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            329..1174
                     /locus_tag="NOB46_000784"
     CDS             329..1174
                     /locus_tag="NOB46_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1057746.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1455..2675
                     /locus_tag="NOB46_000785"
     CDS             1455..2675
                     /locus_tag="NOB46_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HCI1057747.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2672..5392
                     /locus_tag="NOB46_000786"
     CDS             2672..5392
                     /locus_tag="NOB46_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1057748.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5376..6320
                     /locus_tag="NOB46_000787"
     CDS             5376..6320
                     /locus_tag="NOB46_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1057749.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6389..7399)
                     /locus_tag="NOB46_000788"
     CDS             complement(6389..7399)
                     /locus_tag="NOB46_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1057750.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7579..7923)
                     /locus_tag="NOB46_000789"
     CDS             complement(7579..7923)
                     /locus_tag="NOB46_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI1057751.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7916..8350)
                     /locus_tag="NOB46_000790"
     CDS             complement(7916..8350)
                     /locus_tag="NOB46_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCI1057752.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8488..9225
                     /locus_tag="NOB46_000791"
     CDS             8488..9225
                     /locus_tag="NOB46_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057753.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9218..10429
                     /locus_tag="NOB46_000792"
     CDS             9218..10429
                     /locus_tag="NOB46_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057754.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10633..11415
                     /locus_tag="NOB46_000793"
     CDS             10633..11415
                     /locus_tag="NOB46_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HCI1057755.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11485..12147
                     /gene="trmB"
                     /locus_tag="NOB46_000794"
     CDS             11485..12147
                     /gene="trmB"
                     /locus_tag="NOB46_000794"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCI1057756.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12245..13999)
                     /gene="ade"
                     /locus_tag="NOB46_000795"
     CDS             complement(12245..13999)
                     /gene="ade"
                     /locus_tag="NOB46_000795"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCI1057757.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14131..15060
                     /gene="tadA"
                     /locus_tag="NOB46_000796"
     CDS             14131..15060
                     /gene="tadA"
                     /locus_tag="NOB46_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCI1057758.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15017..16066
                     /locus_tag="NOB46_000797"
     CDS             15017..16066
                     /locus_tag="NOB46_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HCI1057759.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16063..16341
                     /locus_tag="NOB46_000798"
     CDS             16063..16341
                     /locus_tag="NOB46_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCI1057760.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16316..16786
                     /locus_tag="NOB46_000799"
     CDS             16316..16786
                     /locus_tag="NOB46_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCI1057761.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16803..17105
                     /locus_tag="NOB46_000800"
     CDS             16803..17105
                     /locus_tag="NOB46_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057762.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17122..17493
                     /locus_tag="NOB46_000801"
     CDS             17122..17493
                     /locus_tag="NOB46_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HCI1057763.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17465..17824
                     /locus_tag="NOB46_000802"
     CDS             17465..17824
                     /locus_tag="NOB46_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057764.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17996..19003
                     /locus_tag="NOB46_000803"
     CDS             17996..19003
                     /locus_tag="NOB46_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1057765.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19028..20212
                     /locus_tag="NOB46_000804"
     CDS             19028..20212
                     /locus_tag="NOB46_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCI1057766.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20649..22232)
                     /locus_tag="NOB46_000805"
     CDS             complement(20649..22232)
                     /locus_tag="NOB46_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1057767.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22810..22953)
                     /locus_tag="NOB46_000806"
     CDS             complement(22810..22953)
                     /locus_tag="NOB46_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HCI1057768.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23176..23655)
                     /locus_tag="NOB46_000807"
     CDS             complement(23176..23655)
                     /locus_tag="NOB46_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1057769.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23728..24012)
                     /locus_tag="NOB46_000808"
     CDS             complement(23728..24012)
                     /locus_tag="NOB46_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057770.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24090..24284)
                     /gene="ssrS"
                     /locus_tag="NOB46_000809"
     ncRNA           complement(24090..24284)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="NOB46_000809"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24356..25642)
                     /locus_tag="NOB46_000810"
     CDS             complement(24356..25642)
                     /locus_tag="NOB46_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCI1057771.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25780..26451
                     /locus_tag="NOB46_000811"
     CDS             25780..26451
                     /locus_tag="NOB46_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCI1057772.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26417..26905
                     /locus_tag="NOB46_000812"
     CDS             26417..26905
                     /locus_tag="NOB46_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HCI1057773.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26918..27865
                     /gene="prmA"
                     /locus_tag="NOB46_000813"
     CDS             26918..27865
                     /gene="prmA"
                     /locus_tag="NOB46_000813"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCI1057774.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27866..28630
                     /locus_tag="NOB46_000814"
     CDS             27866..28630
                     /locus_tag="NOB46_000814"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCI1057775.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28863..31076
                     /locus_tag="NOB46_000815"
     CDS             28863..31076
                     /locus_tag="NOB46_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCI1057776.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31087..31533
                     /locus_tag="NOB46_000816"
     CDS             31087..31533
                     /locus_tag="NOB46_000816"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCI1057777.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31704..32963
                     /locus_tag="NOB46_000817"
     CDS             31704..32963
                     /locus_tag="NOB46_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HCI1057778.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33052..33999)
                     /locus_tag="NOB46_000818"
     CDS             complement(33052..33999)
                     /locus_tag="NOB46_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI1057779.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34393..35685
                     /locus_tag="NOB46_000819"
     CDS             34393..35685
                     /locus_tag="NOB46_000819"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCI1057780.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35700..37469
                     /gene="aspS"
                     /locus_tag="NOB46_000820"
     CDS             35700..37469
                     /gene="aspS"
                     /locus_tag="NOB46_000820"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCI1057781.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37578..38453
                     /locus_tag="NOB46_000821"
     CDS             37578..38453
                     /locus_tag="NOB46_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1057782.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38719..40602
                     /locus_tag="NOB46_000822"
     CDS             38719..40602
                     /locus_tag="NOB46_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCI1057783.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40677..40961)
                     /locus_tag="NOB46_000823"
     CDS             complement(40677..40961)
                     /locus_tag="NOB46_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI1057784.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40951..41685)
                     /locus_tag="NOB46_000824"
     CDS             complement(40951..41685)
                     /locus_tag="NOB46_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCI1057785.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41814..42437
                     /locus_tag="NOB46_000825"
     CDS             41814..42437
                     /locus_tag="NOB46_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCI1057786.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42629..43750
                     /locus_tag="NOB46_000826"
     CDS             42629..43750
                     /locus_tag="NOB46_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCI1057787.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43757..46885
                     /locus_tag="NOB46_000827"
     CDS             43757..46885
                     /locus_tag="NOB46_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HCI1057788.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46904..50098
                     /locus_tag="NOB46_000828"
     CDS             46904..50098
                     /locus_tag="NOB46_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HCI1057789.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50244..50951)
                     /locus_tag="NOB46_000829"
     CDS             complement(50244..50951)
                     /locus_tag="NOB46_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI1057790.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51716..52114
                     /gene="spxA"
                     /locus_tag="NOB46_000830"
     CDS             51716..52114
                     /gene="spxA"
                     /locus_tag="NOB46_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI1057791.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52446..53099
                     /locus_tag="NOB46_000831"
     CDS             52446..53099
                     /locus_tag="NOB46_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HCI1057792.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53325..54323
                     /locus_tag="NOB46_000832"
     CDS             53325..54323
                     /locus_tag="NOB46_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HCI1057793.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54499..56307
                     /gene="pepF"
                     /locus_tag="NOB46_000833"
     CDS             54499..56307
                     /gene="pepF"
                     /locus_tag="NOB46_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCI1057794.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18555 a         9728 c        11685 g        16420 t
ORIGIN      
        1 aggcaaaaag atgaactaga aatagttcat ctttttttgt ttaaatcttt tgctaagttg
       61 aactaataga gtcttttatg aatatcgaag ttagtttttc acctaacttc gttttttata
      121 gttggttatt ataaaatagt aatatagctg atttggattc aattcatatt tatttataaa
      181 tcaaaaatac agagaatagt atataaatgt cctttcctat tcttaaaatg atgtttgtac
      241 ttacttaaat taggtataat tagtatatgt tttgtgagaa atttagactt acaataagca
      301 gtgaatttat aatcaacgta taggagacat ggatgaaatg aaactaattg gtatagattt
      361 agacggtact cttttgaatt ctgaccagag cattagtcaa aaaaatgcaa gaacaatgaa
      421 acatttaccg gaagactgtt ttccattcat ttgttctgga agagaagtag aagacattaa
      481 taatattctc aaaaaatctg gtttaaggat accagcagta gggttaaatg gttctgttgg
      541 atttgatgga gaaaaaaaga tatttgagtc ttccttcgat aaaaatgatg taaaaaaaat
      601 tgattctgtc ctatcgaaat ttccaaccaa aatatataca aatctcggaa gttatgaatc
      661 tcagaattat aaaaataaaa tgaaaaaaat ttttcacgag gtagggagtg aattttctat
      721 caaagagcta aactatgagc ttgagtatga aaaatctatt tgttcaatcc cttataataa
      781 tattgaggaa attatagaaa aggatgctat cagcatttac aaatttttta tttttattcc
      841 taatcgtcaa ttgaaagcta atatatttaa ccatttgaaa aagatgctaa atgtgtctgt
      901 tactgaatcg gcacctgtaa atattgaaat cgtacctcaa aatgtatcta aaggtgtggt
      961 gtttgatcgt ttggaatcaa tctacaattt aaagaaacct ttgagaatcg cgatcggaga
     1021 tagtttaaat gacttatcta tgtttgaaag tgcagatatt agttttgcaa tgggaaatag
     1081 tcatcaagaa atcatgaaaa aagctgatta tgtcactgtt tcaaatgata aagacggagt
     1141 atctcaagca tttgaaagaa ttcttaccat ataaactaat taaggtagta tagaacatag
     1201 aattctaaat acggaaaaat ggagcataaa ttccagtaca aatagtactt cttcagtgtc
     1261 aaacgaagcg aatataacat agatatttag gattgtgaca aaaatcatgt cacaatcttt
     1321 ttttcgaata aacttatttt ttgaagtcgg ccatttatcg taatttcttt gcataatacg
     1381 aacaaatttt cggttattga tgaaaaaaaa cattgaaaat ggtatgataa aagaaaaaaa
     1441 ggaggaaatt tttaatggtg aaatttatcc atgcggcaga tttacatatg gatcggtcat
     1501 ttgaaggact gacaactctt gataaaactg tacaggaaaa actattgaag acgaatctga
     1561 ccgttttatc aaatatcatt gaacaggcaa taataaataa cgttgatttt gttttacttg
     1621 caggagataa ttttcatcaa aatcgtcctt cattaaaaat acagaaacat ttttcagaac
     1681 agatgaaacg gttagaaaag aaccatatac ctgtatttat aatattcgga aatcatgatt
     1741 tctatcaaaa agagcggtat tggttctcct ttcctaaaaa tgtccattta tttacatccg
     1801 aaacggtaga gacaaaaaaa ataacgataa aaagtggaga aactgtctct ctcagtggat
     1861 ttagttatcg tcaaccgtgg attcaaaaag acaaagtgat ggaatttcct tctagagaac
     1921 tcacagatta ccatattggg ttgtaccacg gggaacctgg cgtctctcaa aaaggaaact
     1981 atgctccttt ccaaccctca aagatgcaag aaaagggata cgattattgg gctttagggc
     2041 atatccatgt gccaacggtc ttaaatgaaa agcaaacaat tgtttatcca ggtgcgcctc
     2101 aaggtcatac taaaaaggaa caagcttcta catctattct actagttgaa ttaagtaaag
     2161 gaagttgcca aatacatccg attaaagtag cagaggtcta ttggaagaca aaggaaatat
     2221 cattgaggaa agcaagaacg acaaaagagg tcattgttca cattcgtcag cagctttcaa
     2281 aagtagagga tggatttagt ttaattgaga taaaattaaa agattatgac catctcaata
     2341 cagatgtttt ggaacggata caatcaggag agctattaga ctatttgtta gaggaattct
     2401 cagataggat aaatgatttc tttatttggc gtatttctct catagagaat actttttata
     2461 cgaagacccc acttgctgct tctgctaaat tgatggaaca gttatttcaa tactatcaga
     2521 cacctcaaga tttccaacaa attttaaatg aagtatatag tcatcaagaa gcggctagaa
     2581 tattgagcga actgccggaa tatcaagaag aaacacttga aaaagccaag cagctgctta
     2641 atcaagattt tttatttgag gaggatcagg aatgaagatt ttaaggatcg agattgctgc
     2701 ttttggaaaa tggcgtcaaa aaagttttga cttttattca ggcaatcagc tgatctatgg
     2761 gggaaacgaa gcaggaaaat caacgattta tcaatttatt caagcaatat tatttggttt
     2821 cccttcaaaa ggccgtaaaa aaaaggatta tacaccaaaa gacggctcag cctatggcgg
     2881 caaaatatgg cttaaacatc ctgtatatgg tgaatttgct gtcgagcgct acaagcagca
     2941 aaatcgcgga aaatcgaagg tgtggctggg ggatcaagtg ggaagtgatg agttactaga
     3001 aaaactgatc gcacctttga cgaaagagtt attccagcag gtatttactt tccagcaaga
     3061 gcagttgatg gaactagatc atttgagaga aaaagagcta catgatgcgc tgatttcttt
     3121 aggcatcacg ggcagttctc aagtattcca aaagcggcaa gaatattatc agaaagcaca
     3181 acaattattc aagaaaaaag gccaaaaatt actaatcaat caaaaattaa atgaatggaa
     3241 agagctgcaa gaaaaaattc atcaaaaaca agaacaggaa gcttattttg gcaagttgat
     3301 ccaacaagaa caggaatacg agtcgcaaca gcagcagtta ttggcacaat taaaagaggc
     3361 gaacaaacaa ttttcattag ccagacagca agaacttaat ttttctttat atgaagaatg
     3421 gcaatctctc aaaaaaaaca gcactacagg tcttcctgat gagcaacttc ttttagatct
     3481 ggagtctttc tccaaacggt atcagcaaac aaatgagcgt ttggaagaat tagaagcaac
     3541 actggaaaag catagcggga tggatcagca gtcagccaga tattattttt atttagagca
     3601 ggagcaggaa ctaaaagatc tccagcaact tcaatttaca gcggaacaat taaacgaaga
     3661 atggcaaaga ttacaaattg agactagaga aacaaattca gaattgaaga ttttggaaca
     3721 aaggtggcat tggcagaaaa atccgttacc ggaagaattt ttatatgaag aagaatggaa
     3781 gcatcttctg gctgaagaaa gaaggattgc tgatctagaa agccagattt ctgtgcgtct
     3841 ccaaatagct aaagaacagc aagagatgat tgaagcagaa gtgaatgact tggaagagac
     3901 ctatccagca ttattacaaa atcagtcaga gatagcacca gtctcttcat ctaaaccgta
     3961 tatgctgatg gctggcggag caataatcat tgcaggtata tttgtaccaa tgcccttgaa
     4021 agtgatcctt ttactaattg gtgcaggcat gattggctat ttcttctaca aaaggcaacc
     4081 aaaaattaaa actaaaaatg atttctctga gataaaagga atgtggcaag aaaaactagg
     4141 acaacttgat ctagccttag ctcaattagc tgaagcagaa gaaaaacaaa agagaactgg
     4201 agaagaaaaa cagattcttc agcaagaagt atatcgtttt gcggatcatc ggcacttagg
     4261 aaagatggat acgctcaaac tcatgaaaga atatggacag gaagtcatag attatcagaa
     4321 attatatggc gtatttgagc ggaaacataa aagagaacag gaaatacaag aaaaactacg
     4381 acaaatcgac caaaaatttg agtttgttaa agaatggtta ccgatacaag ataagacaat
     4441 ttcagaaaaa atggtattgc tttcccgttt tatacaagag atggaacaga tgaaatttgc
     4501 cagaagctat cagcaaaata ctttattgaa gcaagaaatc aatcaattga aaaagaaaca
     4561 aaaagtatgg atacaagaat acagcgaaca attgactcaa gcaggcttat cttatccttc
     4621 ggaagtacct gtctttttac aaaaagccaa acaagccgaa cagcagatga aaagatacaa
     4681 tgaattatcg gaaatgctta ctccactatt tcctgaagag ctgacaaaag agaaattatc
     4741 tgtaagactg cgccaactga aagaaaagca atcccaactc cagcaagaag aaaaagaagc
     4801 aagtgaaaat cggcaacgac tccaacttca agtagaagag ttgcaaagag acggcacatt
     4861 ggacgaactt tatcaacaag ctagccggca aaaagcaaaa ttacaggaat tactggagga
     4921 atggggagca cttgaaatcg ccgggacatt cttaggtgat ctttcaacag agatgagtga
     4981 aagacaatta ccccagttgt taagagcagc aggtgattat ttaggtattt taacaaaagg
     5041 aaattatcag aagatattac tgaaaaatga tacactgact ttaacagacg gatatacaga
     5101 atttcccatc tatgagttat ctacaggtac gaaagatcag ctgattatgg cgatgagatt
     5161 tgcttacctc tcattagaag ctaaccgttc gatatgcccg atcatcattg atgatggctg
     5221 gcttcattat gatcatcagc gaaagtatca attagctgaa cttttagcta aatttggaga
     5281 aaagtatcaa ataatttgtt tttcttctga taaagaaatg gtaagctatt accatgagat
     5341 gaaccaaatc gtaaaacaat tagaaggagc aaataatgaa aaaaattcgt gatttagtaa
     5401 tcgatgagca gtttgaacaa tttgtcctga tcaaaagtgc agatgtaaga atcgctaaaa
     5461 acggaaaaaa atttattgct tttactttcc aagatacttc aggtactatc gatggtaaat
     5521 actgggatgc ttcggaggag gaaatcaata aatttacagc cggcacagtc gtttttctaa
     5581 acggtaaaag agaggtttat caaggaaacc ctcaagtaaa gattcttcat atgcgcttaa
     5641 caagggtaga tgagccagga gagcctagtt tatacatgga aagagcccct ttgaagaaag
     5701 aagaaatgga agaagaaatc aatcaattgt tgtttgagat caccaatgcg cattggaatc
     5761 gtattgttcg ctatctactt aataaatatc aaaaacaatt ttttgagttt ccggcagcaa
     5821 aaagaaacca tcatgcattt gccagtggat tagcttatca tactttgaca atgcttcact
     5881 tagggaaatc aatcgccgat gaatatcctg agctgaatcg agcattgttg tatgctggta
     5941 tcattttgca tgatttagga aaggtgattg aactttccgg tcctatgtcg acagaatata
     6001 cgcttgcagg aaatttgatc ggtcatctgg tattgattga cgaagaaata actaaagcct
     6061 gtcttgcgtt gaaaatcagc gaagctgacg aagatgttct cgtattacgt catatggttt
     6121 tagcacacca tggcttatta gaatatggct cacctgtacg tccaagaata atggaagcag
     6181 aaatattaca tcaaatcgac aatatcgatg cttcgatgca gatgatgttg acttcgattc
     6241 gtcaaacaga accaggaaaa tacaccgatc ggattttcgg tatggacaac cgaagtttct
     6301 atgtaccaaa agatttatag caaaaattta tttttttcat tcaaaacaaa aaaagcgaga
     6361 cataagtctt cgcttttttt gttttctttt attttgatga atcagttgtt tcttcagttg
     6421 aagattcttt tgttgaatca gttgattttg tgtcagaact ctttgttgaa gctgtagttt
     6481 cacttgagtc tttcgtactt gatgaagttg ttgtgaatgc actcaacaca ttttcaaagg
     6541 catcatcttt gatttttaca tttgcatctt ttaattcttc accgattact ttagttgtga
     6601 atgcattgtc acttagttta gtttcagtag cgatatcttt tagttgatct ttgtatttat
     6661 ccatgtcatt gcctttattt tggtttttca ccattttgac aacgtagtat tctgtcgcat
     6721 aagaagtagg atttgttgta gtaataacat cggagatctc accgtctttc aatttgaaag
     6781 ctgcttcttt tacttctgca ggaatagttg ttgtcgttga gtcgaattta actttaccgc
     6841 catcttcttt tgtctctgta tcagttgatt tgtctttggc taatttagag aaatcatctc
     6901 catcatccgc tgattttttc acatcttttg cttcatcttc acttgataat ttgatgattt
     6961 gtgcttctac ttctggatgg aaagatttcc aagcagtttt caaatcgtca tctgtaatat
     7021 ctacgtgagc tttcaagcca gcttcaaaag ctaaattgtt acgaatatat tctttataag
     7081 tatctttcgt atatccagca gcttctaatt gtgattcaaa agtatcacct aatgatttcg
     7141 cttgtttgtc gtattctgca tccacttgct tatcggttac tttatcgcca tatttgttat
     7201 tgaatacttt ataaatgatc atccgttgta ctaaggattg gttcgatgat tcaagttttg
     7261 cttcatcata gaaatcagat acagtgatcg ttccgccttt catcgttgcg atatctttat
     7321 tagtatcgcc tgaacaagct gctagagtta aaacagccaa cgcactagta gctgccaaaa
     7381 taattgattt ttttttcatt aaaatttgca ctcctgtaat tagttattat ttttatatat
     7441 taactatacc atatcccatt tcctttaaaa acgttgtcgt ggtagtttca aacaaaattc
     7501 aaaatttcat cacattccta ggaaatacgc aaacttttct cacttatata gttaaatctg
     7561 ttgagaaaat aatcattatt atatttgttc aggatactct ggcagatcag cttttagttt
     7621 ttctacttgt tcattgattt gtgtgatacg tggttcggct tggaatttaa aatcttcgat
     7681 atcttttttg attgcttctt ggaaagcagg aatcacagat tcagctgttt cttttgtttc
     7741 gatcaatgcg cttttaaaat gattcaggct gttatttaaa tcatttgtca gagttgttgc
     7801 ttcttccaat tcttcgatca gtttctttct tgtttcattc ccgctcctgg gcgccaataa
     7861 cagacctccg acagtgccag cagcagctcc aaataacagt cctttgaaaa agtttttaat
     7921 catcgcagga cacctgcttt acgattgttt cttgaatagc ttttagttct tccgatccat
     7981 aactatcttg atgattgaca aagtgaatag aaaaatcatc ctctttgctg tagcgaggga
     8041 ctaaatggat atgtgaatga aaaacagatt gataggctag ttcacggttg ttattcaaga
     8101 tattaagacc tttcatttct ggaaaagctt tttccaatgc ttgagcaatc ttaggcacac
     8161 gcgaaaaaac ctctcctgca agttcgggat catattcaaa aatatctgct acatgacgtt
     8221 taggcacaac taatgtgtgt cctttcgttg cttgagagat gtctaaaaaa gcatagacct
     8281 tgtcgtcttc atatatttta tagcttggga tttcttgatt gatgattttg caaaaaatac
     8341 agttttccat ataaaacatc ctttctataa agaataaata cttcagctta actttaccat
     8401 aagttaaagc tattgtaagg aaaaaaacaa aataccgtca ttttcttcgt ggtataataa
     8461 ataaaaataa atggcggagg aaaaagaatg agtttaatta tcgatcatgt cacagggggg
     8521 tacggacatc tccctgtgtt aaaagatatc agtttcgatg tacagcctgg agagatagta
     8581 gggttgattg gactgaacgg agcagggaaa agtacgacca tcaagcacat tatcggtctg
     8641 ctggaagctt caaaaggaac gatagaaatc aatcatctat ccttaaagaa aaatacggaa
     8701 gaatatcgca aacaaattgg gtatattcca gagactcctt ctttatatga agaattgaca
     8761 ttgagagaac atatcgaagt cactgcgatg gcctacgata tacctatgga tatagcaatg
     8821 aaaagagcag aaaagttgtt ggagactttt cggttatcta atcgtcttga ctggttccca
     8881 gctaattttt caaagggaat gaaacagaaa gtgatgatct tatgcgcctt tttgatcgag
     8941 ccttctttat atatcatcga cgaaccattt ttaggcttgg atccactagc tatcaatgca
     9001 ttgcttgaat tgatggtaga aatgaaaaaa gaaggagccg gtattttgat gtctacgcat
     9061 attttagcta ctgcagaaaa atattgtgat cgttttgtgg tcttacataa cggagagata
     9121 cgagcagacg gttctcttga gatgttgaga aaagaatttc agctgccgga ttcttctttg
     9181 gacgaaatct atattgcttt aacaaaggag caggcacatg agtagttttt ttcaaaaacg
     9241 tttagcaaga catcaaaaga aaatgatgaa atatatgcgt tatgtattga acgatcattt
     9301 tgttttagtt tgtcttttct tgattggcgg tgtgggatta tattattcta attggttgaa
     9361 aaccctgcag ccaccgtttg caattggagg gctcataatc tctgtatttt ggatgctctg
     9421 tttattcgtg ggtaagatgg ctacttttgc agaggcagca gatattgttt ttttacttcc
     9481 taaagaaaaa gaaatgcaaa cctatttgga acgagctttt cgctattctt gcatttttcc
     9541 gttgatcttt ttgatattgg catgcggatt ggccatgcca ttagtggtgg ttagtacgga
     9601 gcaatccttt tcgatgtttt tcgtctatct gatcatatta tggagtttga aattcagtca
     9661 tctgcaaatc aagagagcag aattgtttcg actagatcaa caagttattc gttattggaa
     9721 attaggctgg tttttttctt ctctgatctt tttgtttcta tcattttatt ggctaatatg
     9781 ggcaggaata gcaggtgcat tagtacaggc aagtctatat tactggtttt tgtggaagca
     9841 acaagaaaaa ggattggatt gggagaaaat ggtgcatgta gaagaacata ggttgcatca
     9901 gatctatcaa tttatcaatt tattcacaga tgttcctgaa attacggcaa agatcaaaag
     9961 aagacgctat ttggatccta tattgactca tattaaaaga gaatcaaaaa acacttatct
    10021 ttacttgttt gcaagaagat tggcaagagg ttctgatttt agtggtcttt atttccgatt
    10081 agtaattata ggtgggttat tgattgccgg agtagtcgac ttttatttta gtctgattat
    10141 cggtttctta tttttatatt tgatcggttt ccaactgtta cctttagcga accagttccg
    10201 ctatatggtt ctcgttcagc tttatccaat ccataagaat cagaagaagc aggcgattca
    10261 gtatctactc acatgggtat taattatcgc gtcggttatt tttggtttga ttgctgcagt
    10321 cgtattagat gggcagcagc gatgggttcc gctagcggct tatttgattg ttactatgct
    10381 ctttgttaaa ctatatgtac caactcgttt gaagaagatg tcagactgaa aacaaagctg
    10441 tgtagggtaa aaatgagaat gaaaaataga gcgttgacag taagaatgct gttcgttcta
    10501 ttttttttga gaaaagctgg ttttttgaat ggcaattaaa tgaaaaagaa cgtatatgtg
    10561 cttgacgtgt agtgttcagg cgactagaat aataagtact gcaaaacaaa gagtaagagg
    10621 acgggagaat gcatgatgga gtttcagtta gaccaagagt ggcggttacg tcccatcaaa
    10681 ggcgacacag gaaaaacata cataggcatg cgtgatgagg acaaagtctt tattaaacga
    10741 aacacgactc cgatgttggc tgctctttca agggaaggaa ttacaccaaa acttgtttgg
    10801 acaaaacgaa cggggaatgg cgatactttg acagcacaag agtggctgga aggtcgcttg
    10861 ctgactccta atgagattgg tcaaagaaac gacgtgattg atgttttgta ccatttacat
    10921 cattcaaatt ctcttaaaac catgctgacc cgtatcggtg gtcgtgtcat gacgccggag
    10981 aagatgctgc aaaaatatga aaaagaatta ccggaagaac tccagaaaaa tcaatttctg
    11041 caaattgtcc atcgttttct tcgtgagcag atcccgtcaa tagataagga aaacttatca
    11101 gtagtacacg gagatgtaaa ccatcgtaat tggttagtat gtaaaaatta tttatatcta
    11161 gtcgattggg attcaatcat gtttgcagac cctgcggtgg atattgcaac gattttagga
    11221 aattatgtgc cactgtctag ctggaatcag tggctgatca gttatggcat acgcccgact
    11281 gacgaaatgc ttgaaaaatt tcattggtat gcggccatga atttgctcca agaaatcacc
    11341 agatattgca aacgtgaaga tcatcgacgg atgaacgaag aaattttaca attaaaacga
    11401 attttcagtg gctgaggttt ggcccaaact ctgcggagat ttggccagac ctttttaatt
    11461 agaggaaagg aatggagata aataatgcgt gtccgaaatc gtccgggagc agcggaaatg
    11521 ttagcggctc acccgaattt tgtaattagt gatccaacat tgtggaaggg aaaatggaat
    11581 gaattgtttg aaaacgatca tccaatccac attgagattg gtatggggaa aggccagttc
    11641 atcactggaa tggcaaaagc ccatcctgaa atcaattata ttggagtaga aatgcaggtc
    11701 agtgttgttt cgattgcact agacaagttg atcgaacaac cgcttcctaa cctgaaactt
    11761 ctacatgtgg atggatcagc gttgacagag tatttcgctg acagcgaagt agatcaaatc
    11821 tatctgaatt tttccgatcc atggccaaaa aaacgtcatg aaaaacggcg attgacatat
    11881 aagacttttc ttgctgtaga tgaacagatt cttcgtccaa atggagaaat ccatttcaaa
    11941 acagataatc aaggattgtt tgagtattct ctggcaagtt tttctcaata tggcatgatc
    12001 ctcaaacagg tatggttaga tttacatcaa agtcaatttg aaggcaatat tatgacggag
    12061 tatgaagaaa aattttcttc aaaaggtcaa cgtatttatc gagtagaagc tcaatttcaa
    12121 gataagacca aaaagaaaag tctgtgaaac taactttctg ctttcataaa aacattaata
    12181 tccataaata aatcccagaa aatgaacatt acagatgtaa tgtattttct gggatttatt
    12241 tgatttaaaa tgtatttatt tcatcggttt ttccacaagg tggaatcaat tggaagcgag
    12301 aaaatgaaaa taatcctttg tcggtgatct tcaattcggg tatgacagat aatgttaaga
    12361 aagaaagtgt caaaaaagga tcaaaggttt tagctgctcc tagttgatgt gctttagtta
    12421 ttaattcatt caactgttca tagacgatcg aaaaaggttc ctgtgtcatg attccgccta
    12481 taggaagaga aacacaagct atttcctgct gtttgttgac aacggtcatc ccgccacctt
    12541 tttgaatcaa aagattagca gcatacagca tatcctcgtc gtttgtccca acgacaacta
    12601 gattatgcga gtcatgggca atcgttgtcg ctatcgctcc ttgtttcagc tgaaatcctt
    12661 tcactatgcc taatccaatg tttcccgttt gatggtgacg ctcgatcacc gcaatcttta
    12721 attggtcttt ttcgattgaa ggaatgaatc gttcgccttg tcggtccact ttttctacca
    12781 aatctttagt cactagacta ttcgggataa tttcgatcac atgggcttgt gaagaagaaa
    12841 gaagcagctc taacgaatgt ggatttaatg gttgagcgtt tagttttggc agacaacacg
    12901 tatatgaatt tgaatgatca gcaaataaat ggtcttggag ttgcccagat tgaacaacta
    12961 atgttccctt atagaaaact tcatgaattg gcagcttggt aagatcgtct gttaagaaga
    13021 aatcagcttg atacccaggg gcaatcgcac ctagtgtttt caaatcaaaa cattctgctg
    13081 cattcaatgt tgccatctga atggcttgta atggatcgat tccaagtgca atagcttgac
    13141 ggacgatatg atcgattgat ccttctttta ctaaatcatt gatcagttta tcatcggtga
    13201 caaagaagca tcttcttgaa ttttcaggtg tgatcgccgg tagtagcgat gccagatctt
    13261 ttgcaacggt cccttctcga accattaaat acataccaag atccaaacgt tctttagctt
    13321 cttttgcagt tgtagcttca tgatccgtcc gaatacctgc tgcaggataa acatttaact
    13381 cttccatgcc gataccagct gcatgcccgt caattttttt cttatgctgg tgcatcaatt
    13441 ggatcttttc taggatgtct gtttcattat ttgctactgc ttgatagttc atgacttcag
    13501 ctaagcctaa aacttcgggt ttttgtaaaa aaggggctaa tttttttgca tttaaatttg
    13561 caccattggt ctcaaaaggg gttacaggta cacaagaagg tagcataaaa aagatattca
    13621 tgagtgtttg tcttgcatct tctatcataa actcaagacc tgtactccca gcaatgtttc
    13681 ctatttcatg gggatctgtc actacagtag taactccatg aagcaaggat acttttgaaa
    13741 attcgcttgg tgataaaagt gagctttcga tatgcacatg gccatcgatg aatcctggca
    13801 ctagatattg cccattagca ttatgtacgc tttttccttc gtattcaccg attcctacga
    13861 tcattccttc gcagattgct acatcttttt ccatgatttc tttcgtaaag acgttgacga
    13921 tcttagcatg cttgatcact aggtcagcag gctttttttt acttgctact tcgatatatt
    13981 tccttaatgt tgtttccaat ggagtgcctc ccaagataaa tttttataag tataacataa
    14041 attcggtttt tgccaatatt tttttgtaaa ttcattttat ttgaaacaaa aagatcaaaa
    14101 agacgtatgt tttttgtgga ggggagaata atggaaataa aacgattatc ggatcaaatg
    14161 ataagtgaaa gttttgccaa acatgcccaa gacgtatata tattgccagc ttcagaagta
    14221 ttttacatct attttcgcta tggaaaaaaa cgaacattct ggaagaaagt ctcttcggca
    14281 gatggacagc aactgatctc aagatttaag tatttgggac agatggatat cggagaaaaa
    14341 agaaaagctc agttaggtgc atttacttat tctttagaaa aacaggaagt tcgtctgcgg
    14401 ttgtcttctg taggagatta ccttcaacga gagagtttag tgattcggct attatacggt
    14461 acttttgaaa caccccatcg ttgctttagt tctcgagatt ttgcaactat tttacagaaa
    14521 accgtcagac gtggattata ccttttcagc ggaccagtcg gatcaggcaa gacttctcta
    14581 atgtatcggt tggctttgga agaaaaattg caagtgatta ctatcgaaga tcctgtagag
    14641 atagaagaac cgttttttct gcagctacag atcaatccga aaatagcaca gacttatgat
    14701 acacttttga gactcgcatt acggcatcgt ccagacttgc taatcattgg cgagataaga
    14761 gatgaatcaa ctgcacatgc tgcggtaaga gcagcactaa cagggcaccg ggtttttgca
    14821 accgtacatg cacgcaatct tgaaggtaca ttggtcagaa tccatgaact gacaaagaaa
    14881 aaagaagagc tatctgaatg tttagctggt gtcatttatc aagaactttt ggaagatgcc
    14941 aatcaccatc cttctgtttt atggagttat caatttatgg aggaagaatc agtaaaaaaa
    15001 tcatgggagg aaagttatga agaagctcag gaaaatattt ggcagtcaga actattctaa
    15061 aggattaaca agaagccagc aaaaccagtt tgcacaaacc atgggagaac tgcttttatc
    15121 tggttttagt ctgcaagaat ccctttattt attactcacg atccgttcgt ttccacctgt
    15181 tattttggca aatatccaac atcagctaaa ggaagggcaa gcgtttagtg aggtactttc
    15241 gcaaatagga tatggagcag agcaactggt acagatcgag ttagctgaac gtcatgggaa
    15301 tctgccgaca actttgttgg aaattgccaa acagtttcgg cttgttgaag gatttcgcaa
    15361 tgatttgaaa aagctgcttg catatccgat gctattgctc acctttttgc taggtatctt
    15421 gtttagtatg cggttgttcg ttttgcctca gcttattggt tcaggaatgg tcatgcaaga
    15481 gcattggggt attcagctga tacaagtctt tcattggtat gttctactat tcatcctagc
    15541 ggttactcta ttggctttac tagtaaggta tcgtctgatg aagttgtctc ctgttgatca
    15601 gagtgaatgg ataagcagac aattattgat tggaccgata tattccttgt atcaatcggc
    15661 ttatttgtca ctagagattg gaaagctttt tcatgaaggt ttcgaattaa ggcaaatcat
    15721 agtctgctta aaggaaacga aacaagaaag tctgattcag catcttgcct ctaagttgat
    15781 tcaaggattg gaggcaggta tgtcattggc tgagcagttc cagaattatc gttttctatc
    15841 agaagaattc agtaaaattg ttttacaggg agaggcaaag ggaagtttag gtaaagaact
    15901 gattttttac agcgaatgga caagaaaaca gcttttcaaa cgtcttcatc actggatgca
    15961 ttttattcag ccaatcattt ttttgggcgt agcggctttg attttattag tttatgccgc
    16021 tgttttatta cctgtttacg gaagcataga ggaggttttg ccatgaaaaa gagaaaaata
    16081 tcttattata gcggttttac attgatcgaa atgctaatcg tcttactgat catcagtgta
    16141 ttagtgttgt tgttcgtccc taatttgtcg cgttatagga atcatgtaga ccaagaaagt
    16201 cgtgaagcga tcatccagtt ggtagacaca caaaaagagc tctatgcgct tcaaaataat
    16261 ggaagagttc ctactgtgga ggaattgttg aatgaaggct atatcaaacg agaacatgca
    16321 gaaatctatc agcggccttg aaggtaaggt tttagcatca ggatatacgt tgtttgaatc
    16381 actcttactg attttattac ttacaacgat cctttctttt ccagttctcg cattttctgc
    16441 atggaagaat gaattggcag tctatcaatt tttcggccaa tttgaaaaac gaatctattc
    16501 tacgcaaaaa atcgctattg tgaatcagat ccaaacaggc ttttattgga atagtgaaga
    16561 gaatcaaatc atttttcatg ttccgaatcc agataaaata aattgggaag tattagatat
    16621 tcctgatgag attaccttga aacgccatgc ttctattact tttgctgcta gaaccgggaa
    16681 tgaaagttca ctaaaagctt atcaatttta ttgggaagaa aaagagcgga cgattacgta
    16741 tcaattccag atagggagtg gtcgctatac aaaaagaatt gaataaaaca ggatttgttt
    16801 tgttggagtc ccttacagcg cttatgatcg cttctgtctg tgtctactta gtgagctttg
    16861 gccagctgtt tttgcttcag gcagaaaaga aaagtgggga ggaactgcta tttattcgaa
    16921 tgatttatga agatatcaag acgcagcgga tgtatcacaa aagaccagag cgaagggaag
    16981 aaatgatccc atacgatatc caaattgtcg ataataatgg agtaatcgaa aaagtgtttg
    17041 tcaatatgga gaaagaagcg atcagtattg aaaaaacaag taattccagc atttacgctg
    17101 attgaatgtc taattggact gatgatattg agcagtctat tgctcacatt caatcttttg
    17161 attcagcaaa ccatccaagt aagtgaattt ttgcagcgta aagatcaaaa agagtggcta
    17221 atatttttag cacaattaga agaagaactc aagagcagtc acaatgtctc tgtgaaaaat
    17281 cagcaactgc actacacgat cgaggataaa cagtatatca tcgaaagata tcaggcaatg
    17341 atacgtaaaa gaagaacttc cggcggacat caacctatgt taacaagtat cactgagctt
    17401 caattattgg aaaaagaaca cacaatttct ttttatgtac actttgaaaa tggagaagat
    17461 ggatatgcca tatggacaaa aaacgatcag tagaaaatgt tataagggct ctattttatt
    17521 ttctgtcttg cttttatttc ttttatgtac gtttttattg atggcagcat tagaaagcta
    17581 ccgtttgtca atggatctta atatacgaat caaaaattat tatatagcaa aaataatgaa
    17641 gcagatggct ttatcggaac agtctacgct tgccgaaagt tcggaaggag ttttttacta
    17701 cacaactgga tctgtaacat atcagtgggt acaacagtcc ctattcttag aggtggaagt
    17761 ctcaccgttt atctttcggt tcacagaaga agtaaaaaat gatacagata ctagtacaga
    17821 atgatggaat gttcgtgaaa acgccctctt ttctgttata acactgtttt taataaaaaa
    17881 atgtttgccg tttcacaaat aaaaaacagt gaaaacgatt gaaattttgt caattgttcg
    17941 atagaattaa acaggtgaaa aaattgttat aatatatcta gaaatgaggt gcaccatgtt
    18001 accagaaaaa atggaacaag ggtttaatca aaacctggaa gctattcagc ttttacagaa
    18061 tgcattggga acttcctttt tagaagccta tgtcgaaaat gcagaaaatt taatagatga
    18121 ttatcaagta cgtgtggtgg atggagtgcc gacaaaagag acaacgcaac ggatcacagc
    18181 tctttatgaa gagttgaaga aactttcttt cgagccagaa gaatggcgca gactgtctca
    18241 attactttta ttgaagggca gccagacaga acatttgcag gcgaaccatc aactcactcc
    18301 tgatagtatc ggttttttat ttgtttttct tattgaacaa ctatacacaa ataaaaaagc
    18361 accggttaag attctggata ttgcggcagg aatgggcaac ttgttattaa cagttctttt
    18421 aaacctatcg aatgcggggt accaaacaga aggaattggt gtggatattg atgatacatt
    18481 gttggctgtc gcagcttcta caagtgattt gacacaagca aatgttcaat actttcatca
    18541 agacgggttg caggaattat taatagatcc tgtcgatttt gcaatcagcg atttgccaat
    18601 cggttattat ccgaatgacg aaaaagcaaa agagttttta acaagtaccg aagaaggcca
    18661 tagttatgca catcatttat tgctagagca atcaatgaaa tatgtgaagc cggatggttt
    18721 tggtttgttt ttgatgccga gtggattttt agaaacggat caaagtgaag aaatcaaaaa
    18781 atggtttaaa gaagaaggtt atcttcaagg aatgattcaa ttgccagatg aattgttccg
    18841 taataaacaa tcgcaaaaaa gtattttgat cttacagaaa aaaggaccac aagcacaaca
    18901 agtaaaagaa gtcttgcttg tgaaacttgc ttcattaaaa gaaccagaga aggtgacgga
    18961 atttttcaac gagtttaaaa actggaaatc atctgctctg taatcattca acgagaagga
    19021 gagtcatatg tctaaaacaa ttgcaatcaa tgctgggagt tcaagtttga aatggcaatt
    19081 atatcaaatg ccagaagaaa ccgtagttgc gaaagggatc gtcgaacgta tcggtttaca
    19141 agattctatt tttaccatca agtacggcga taatcaaaaa ttcgaacaaa tcatggatat
    19201 cgaaaaccac gaagtagcag taaaaatgct gttagatcag ttgattgaac tgcaaatttt
    19261 aagctcttat gatgaaatca ccggagtagg gcaccgtgtt gttcacggag gagaaactta
    19321 tggggattca gtagtgatcg atgagaaagt aatggaccgc attgctgaat tagcagaatt
    19381 tgctcctttg cataatcctg caaacttaat ggggatcaaa gcgtttaaaa agattttacc
    19441 tgacattttg agtgtggctg tattcgatac atctttccac tcaacaatgc caaagcaaaa
    19501 ttatttatat agcttaccgg tgtcttatta tgaagatttc aaagtaagaa aatatggctt
    19561 ccatggcaca agtcatcgtt atgtgtcgga acgtgcggca aaattattga acaaaccgat
    19621 cgaagaacta aaaatcatca cttgccactt aggaaatggt gtatcgatca cagcagtcga
    19681 tggaggtaaa tccatggata cttctatggg attcacacca ttagctgggg tgacaatggg
    19741 tacacgttca ggtgatatcg atccagctgt tctcccatat ttaatggaaa aattagagat
    19801 tgatattgat gaaatgatca atgttttgaa caagaaatct ggtctgctag gcctaacagg
    19861 attgtctagt gatatgcgtg atcttgaaaa gaactatgaa aaagaacata ttcgtttagc
    19921 ttatgacatt ttcgtggacc gcatccgaaa atacatcggc ggttatgtga caacgatgaa
    19981 tggtgttgat gcaattgtct ttactgctgg tatcggcgag aatgacggac atgtacgtag
    20041 tgaaatcatc aaaggtatgt cttggtttgg ttgtgaaatc gatccagcgt tgaatgaatt
    20101 gcgtggtgaa gaagtagata tctctacaaa agaatcaaaa gtaagagtat tagtgatccc
    20161 aacagatgag gaactaatga ttgcccgtga tgtggagcgt ctgcgcggct aagccaaagc
    20221 attcgttagg ataaaagatg aaacgcatgc aagagggaat tcttgcatgt gttttttttg
    20281 cggagaagac cgcaaaatgg taatttaact tcaatttccc ttctttttta caggatcttc
    20341 ttagggaatt ttgcttggaa aagtggtcaa aagggaaaag actggcattt tatttattga
    20401 ttttcaggaa aatcccaata ttttattttc attcatcttt ataagggaca ttacatatgt
    20461 aaaaagaaaa aacattttta gatcagcctc gtgggctgtc gactttattc ttcgctttat
    20521 gtttagctag aaaaccgatc cgaaacattc attgatcgaa taataaaaac ttgattttcc
    20581 acctgtactt tgcctgaatc atgaaagcac aggtatgaaa atcaagtttt ttgttgcgaa
    20641 aaaacgtcct agtcaatcag ttggccgagc ggctggcggc tgatctgctc ctgatcaata
    20701 acgagtgctt cttggaagtg ttgctgcaaa aagtagcggt catggctgac tgctaggagc
    20761 gttccttgat agtcttgcag catttcttca atttcttctc gagcatagct gtcgaggtga
    20821 ttggttggtt catccaaaat caggacgttg attttttcta aaaagagttt cagcaacgcc
    20881 aaacggattt tttcaccacc ggataaatct ttgatccgtt tacccacatc gctttgataa
    20941 aagccacttt tggctaattg ccgtcgagcg acttcttcgt ttccagtcaa tgtgatggcg
    21001 taagccagca aacggctatc gggatcggca aactgcagct gctgcggcaa ataaccgatt
    21061 tgcaagctac tacctaattt gatggtgcca ccgtaaggct tttcctcacc gagtaataat
    21121 ttgagtaagg ttgattttcc tgcaccattg tcgccgatga tggctaaatg atctccacga
    21181 tagactgcaa aactgctgtc tttgaatagt acttgatcag cgtactgctg gtgcaagttt
    21241 tgaatgatga aaacttcttt gccagatttt ccaccattag acaagctttg cagccgattt
    21301 ttcgggggag gtggcggttt gacgagtgtc agtttcgcca ggcggcgttc cagttctttg
    21361 gcttttttga agaaggactc attgtctcct tcatgtgccc actgacgaaa acgacgaatc
    21421 atgactttca accgctggac ttctttttgc tgcagttcgt aattttttgt cagctcagcc
    21481 aagcgagctt ctttcaagac tcgaaaacgg ctgtagtttc cgggatactc aatcaatgca
    21541 ccttcttcca gttcccatgt ttttgtggtg acttgatcga gaaattgccg atcatgagaa
    21601 acgaccagaa ccgatttttt tgtattctgt aaatagtttt ccaaccagcg aatactgtta
    21661 agatctaaat gattggtcgg ttcatcgagt aaaagtaaat cggcatcggc tgctaaaatt
    21721 ttggctaaag cgactttaac tcgttcgcct ccgctaagtt ctgttaaccg tgcttcctga
    21781 cggtgtggaa tccctaagcc ttgcaagatc gctgcaatcc ggtcttctaa tacgtaaccg
    21841 cctagttctt caaagcgatg ctgcagctca ccgtaacggg ccagacactt ctctaagttt
    21901 gtatctggtt ctgtcatcaa tgcttcgtag cgactcattt gctgtttgag gtcctgtatc
    21961 tcagcggcag aatggagcaa gtagtggttg acggtcgctt cggaaactgt aagttcttgt
    22021 tcgaccgtcc cgatctttaa gccttttttg cgactgataa caccgctgtc gacaccttct
    22081 ctgccggtca agatttgtaa aaaggttgat ttgccagttc cgttgatacc gactaaggca
    22141 attttttcac cagcttcaat ttgacaggat aaatcctcaa ataatggatt cccgccgatt
    22201 gtttttttaa tagaaattgc ttgtatgatc atgatctctc tccttgagac cactcaaaaa
    22261 ggccatggtt atccatggcc tgtgttattt aaactcagat tatcatgaga aaaatacctt
    22321 gagatggcca ttgattttac gtgaattcaa ctgttttgga caaacttgtc ccgtcaacag
    22381 caactgtaaa accaattgca tggctaaatg cgatatggta tcgttggtaa ttttcattac
    22441 ttgttatttt agtcatgcgc atcatagtat tttccctcct tcgtgtagtt gtcttttcca
    22501 gtgtacctga aagtgtcaga aagttcaact agcgctgaca tttacttaat atttatcgat
    22561 gtgtaattct gtcagagagc tttttttatc tgactgaggg taatgtctcg tggaccacat
    22621 cattgtattc tgagctaaac cagcgttcag gcgaaatcat atggtgtttg ataaaaaact
    22681 ttgtctacat gacttccttt tgccatttgc ttaataccgt tgcattaaac agctcttctc
    22741 tttggaaatc tcaccaacat cgcgttcagg agtatcgttg tggttgcaat ggcaagcggt
    22801 agcctttcat caattcttga atgatttacc gaatgtagca cttgccttct cgcggtaccc
    22861 gaacccgaaa taaaatttta gtttggcgat aaaatcggta tccgccatcg atacttcata
    22921 ttttttcgta tcagattcat cggaaacttc cacattgacg aaccaataag ctttggcatg
    22981 cttaggtcgt tttaaaccac accagggcga ctaatcgccc tggtgttcac ttttttttat
    23041 tttacttgaa ctcattgact gttttccctt tattttaaac attataaaga ccgatgagtg
    23101 cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa aaaaacctgc cgatagttgg
    23161 caggtcgtct acgtgttaag ctttggtgtg gtctttagct ggcaattggt tttctaaatc
    23221 agttcggaca acaagcacat cgcaagctgc gtttctaata acatattcag aaacagaacc
    23281 aataaataaa cgttctacag cattcaatcc tgtggctcct aacataatca aatctacttg
    23341 attatcttct gggatttctc tggcaataat ttgttttggt gagccatatt ctacgacaga
    23401 ggttacatta ttcaagccag ctttcttcgc attgctttca taatctgcca atgtttgctt
    23461 tgccatttca gtagcttgtt ctgcaagcat tccatcaaag gatgaaacgg tttggaaaga
    23521 acgtgtgtca atgacatgtg ctaatagaag ttctccgtta tttcggatag ctacattgac
    23581 cgccttttta aaagctaatt cagcttcatc agaaccatct acggcaacca tgattttttt
    23641 gtattgttgt aacataagca ttcactcctc aagtcaatcg tattgtactc ttttattgta
    23701 gaacacttta gggaaaaaga gaattattta ctgctttggt tcagcaattt tttttgcaaa
    23761 tcggatactg aaggtggcag aaacaataat tacgatcagt aaaaagacca aggcaataaa
    23821 gcgttgattg aaaaaagctg ttaaaatacc cattacgcct aaaacagcat atgcagctcc
    23881 gtaaaattgt aggaatcctt gatttttatc atttttgttg atcaatacaa aaaagatatc
    23941 ctgtttatta aataaataat agctaacgaa taataatact aaagtggcga taatcattaa
    24001 aatcctaatc atgaacaaat cctccaaaat aagcaacaaa tagaaaaagc aatttgccaa
    24061 gagcaaattg ctttattctt taaaagatgg taatctccgt taatgccgtt gtttgtcctg
    24121 tagtattgat cccgcgaatt caagcaggtg ggtcccatgg tcgtagcttc gaactaccaa
    24181 atgataaggc atgttaccag cagtgacaca agacgggtcc caagatatca ataaaaatgt
    24241 tcggtcaaca cacaaagagg acaattcgaa catcacagat ttcccacctc tatagtagca
    24301 tatgaattta aaaagagcaa tgagagagct cgcagaaaca gaaccgtttt cttgtctagt
    24361 tttttggagg atgctttttc cactctttta tacggtaata ctgttgaccc agagcctgtt
    24421 catatttccc tgtatctttt ggctgataat actgagcatt cttcagttta tctggtaaat
    24481 attgctgatt gacccaagcc tgatcaaaat gatgaggata ctgataaccc acgccacggt
    24541 tgagtgattt cgcacctttg taatggctat ctctcaaatg atcaggaaca tctccagctt
    24601 tgccctctcg aatatcagca agtgctgcat ctaatgccat gtaggcagaa ttggattttg
    24661 gcgacaagca aagatcgacg acgacgtctg ctagtgggat acgtgcctca ggcaatccca
    24721 atttttcagc agctaataca gcgttcactg tacgagccgc agcagcagga ttacctaaac
    24781 ctatatcttc ataaccgata accatcagac gccggcaaat acttgccaga tcacctgcct
    24841 caactaaacg ggcgagataa tgaagtgcag catccacatc acttccacga atcgattttt
    24901 gaaaagccga aataacgtca taatgagcat ctccattttt gtcatgggta agagcttttc
    24961 tttggacaca ttcttcaatg atcgacagtg taagatgaat ccttccttct ttatctgaag
    25021 gagtcgatag tgtagccagt tccagcccat tcaatgcact ccgcaaatcg ccgttcgttg
    25081 cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat tgcttgttgt ccaaggccgc
    25141 gttctttatc ccttaaagca tgttcgactg ccaactggat gtcttgttct gttaatggtt
    25201 tgacttcaaa gatctgtgta cggctgcgga tcgctggatt gatggtaata taaggattct
    25261 cagtagtcgc tccgatcaag atgattcggc cactttctaa atgaggaagc agaaaatcct
    25321 gttttgtttt atctaatcgg tgtacttcat ccaataagag gatcactgta ccactcattt
    25381 ttgcttcttc cgctacaact tgtagatcct tttttgaatc tgtagcggcg tttagcatgc
    25441 gaaatgcata attagtagag ccggcgatcg cacttgcgat actcgttttt ccagtaccag
    25501 gaggtccata tagaatcatg gaagagagca tgcgagcatc gaccatgcgg cgtatgattt
    25561 ttccttcccc gactagatgc tgctgaccaa cgacttcatc gatcgttcga ggtctcatgc
    25621 gataagccaa tggctgttgc ataggatttt cctccttctt gtttttacgt cccttaatta
    25681 tatcatattt agcaagatgc ctagaaagaa cagccttctg ttgttttgtt ttcatagctt
    25741 atccaactaa tattgtgtat gataaagtag gtgagaaaaa tgacggataa acaaaagata
    25801 gatgaatttt tttggaataa aacgacgcca gaagtggcac gggatttatt ggggatgtat
    25861 ttggagcatg acacaccaga aggaagatta gctggatata ttgtagacgc ggaagcatac
    25921 ctaggtccag aagacgaggc cgcccatagc tatggtttaa gaagaacacc gcgtgtgcgg
    25981 gcaatgtatg aaaaaccagg tacgatctac ctttacacga tgcatactca tcggattttg
    26041 aacatcatta ctcagccaga agggattcct caaggagtaa tgatacgtgc aatcgaaccc
    26101 gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa aaactggtcc agatatcagc
    26161 aacggtccgg gaaaattagt ggaagcatta gcaattcctc aagaacttta tggtcagtct
    26221 atagcagata gttcgttacg cttagttttt gagaaaaaaa agacaccaaa aaagatcaat
    26281 gctttgccta gaatcggtat cccaaacaaa ggtgtatgga cagaaaagcc gttgcgtttt
    26341 gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa accaaatcga gaaagattgg
    26401 ggttggagga aagaaaatga aaaagaagga tctattaaca tatttagatg aaataattga
    26461 aaaacaagtg acagactatg atgtagcttt agattgggat acaaaaaatc atacgatcga
    26521 gatcgttgtt cgcttgtttg cagaaaataa agcacaattt gagattgatg atgcagaagg
    26581 gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc gtacttcttt ttaatcctca
    26641 gaaatctgtt tttgatgaac gcaattatct agcagtaatc ccttatgaag gaaaaaaagg
    26701 gttggcaaaa tcagtagctg attctttagt ggaatatcta aatgaagtat tagctcaagg
    26761 gcaaagcgat ttgcttgatt ttttggatga agacgatgac gaagctgtat tcgagcttca
    26821 ctgggataat cagcaactag cagaattagt agaagtaaaa cagcaaaatg aagcagatac
    26881 ttatttaccg tacccaagtt attaaggagt gacagatatg aaatggaatg aagtaaaagt
    26941 agaaactgaa agtgaagcag tcgaagcagt tgctaatatt ttgatggagg caggggcgag
    27001 tggtgtcgcg attgaagatt ctttagatgt tgaacatttt cagtcggatc aatatggtga
    27061 gattttagat aaaaatgatt ttacatcgct gaaagaaggc gcactagtca tggcttattt
    27121 tccggaaacg actttcttac cggaaatctt gccttttatc aaagatcgta tcacacaatt
    27181 acctgagttt ggtctagcta ttggaaaaaa taaagtaaca gttagtgaag tagaggaaag
    27241 caactgggca acagcctgga agaaatacta tcatccggtg cgtattacgc gaatgctgac
    27301 ggttgcgcca agctgggaaa actaccagac agaagatcct ctagaaaaaa ttatcacact
    27361 agatcctggt atggcatttg gcacaggcac tcatcccacg acttccttga cattgacagc
    27421 actagaaaca gtcttgcgtg gtggtgaaac attgctagat gtgggaactg ggtcgggcgt
    27481 gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc tatgcctttg atttagacga
    27541 agtagccgtt cgttcggcga aagaaaatat ggatatgaat gaaatagcca aagatgtcca
    27601 tgtatcagct aacgatcttt tgacaggaat cgagattgaa agtgatgtaa tcgttgcgaa
    27661 cattttagca gatatcatct tattgatgat cccagatgct tggcgtttac tgaagcaaac
    27721 aggcacgctg atcgtttcag gaatcattga agagaagaag caaatggttc tggatgccat
    27781 gttagaacaa gggtttatcg tggatcaaat tttccagcaa aaagactggt atgcaattat
    27841 tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt ttaaaagaat catatgaatc
    27901 aaaagactat tttgttttag aaggggaaaa ctatcaccac attgtacggg ttatgaggat
    27961 ggaacccgag gatgaagttt ttttggcatt caatgatcaa atagccattg ttgcagaaat
    28021 cacggagatt actgaagagg ctgtttatct gaaagaaatt aaaaaagaag aaaatcaaaa
    28081 ggaactgcca agttcgatta ccatagcgag tggctatcct aaaggggaaa agctggattg
    28141 gatcgttcag aaatccactg aattaggagc gcaagctttt cttggtttcc cggcatcagc
    28201 ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga caacaacggc ttgaaaagat
    28261 tgctcaagag gcagcggaac aatcccatcg gcagatcgtg ccatcagtag agttattgga
    28321 aacgaaacaa gatttatttg agcggctaga tgattatgac gtggtcttgg ttgcttatga
    28381 ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa attcttagtg aaacaaaacc
    28441 agatagtcga atcttagctg tctttggacc agaaggtgga ttatcccgcg atgaagtcga
    28501 ttattttgta gaacacaaag ggatactttg tggattagga ccaagaatcc ttcgtacaga
    28561 aacagcacct ctttatttat taagtgctgc tagctatcaa tgggaattaa tgaatccttc
    28621 tttcagctaa cgttcttcat taataaaaga gtatcgacag aaagaattga aaaaatagtc
    28681 aacaatttgt ataatagaaa caattattta tacaatggat acgaaaaatc gtttgaaaaa
    28741 gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac tgcacggatt ttgggacaat
    28801 tatcaaacag atatttgtcc cgattcccgt tttaccgaaa aaagaaaggg ggatcgattc
    28861 ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat aaagctcgtt agtcaataca
    28921 tgggtcccga acatgtagca tttgttgaga aagcatgcga atacgcgact gctgcacatg
    28981 acggacagtt tagaaaatca ggcgaaccct acattattca tcctatccaa gtcgcaggta
    29041 tattagcaga tttaaaaatg gatccccata cagtggctac aggcttctta catgatgttg
    29101 ttgaagatac agaaatcact ttagaagatc tgagagaaga atttggcgat gacgttgcta
    29161 tgttagtgga cggcgtaacc aaattaggga aaataaaata taaatcccac gaagagcagc
    29221 tagcagaaaa ccaccgaaag atgctgctag caatggctca agatttacga gttatcatgg
    29281 tcaaattagc tgatagacta cataacatgc gtacgttgaa gcacctgcga gaagataagc
    29341 aaagaaggat cgctcaggaa actttagaaa tctatgcgcc tcttgcacat cgtctaggga
    29401 tcagccggat caaatgggaa ttagaagata cagcacttcg ttatctaaat ccaaaacagt
    29461 attaccgtat cgtccacttg atgcagacga agagagaaga acgtgaaaaa tacgtaagtg
    29521 gtactgttga agatattcga atagcgacag aagagctggg gatttttgca gaaatctatg
    29581 gacggccaaa acacatttat tcaatctatc gtaaaatgaa agatcagaaa aagcagttca
    29641 acgaaattta tgacttgcta gctattcgag tgatcgtaga ttcaatcaag gattgttatg
    29701 ctgtattagg agcaatccac acaaaatgga aaccaatgcc cggcagattt aaggattata
    29761 ttgccatgcc aaaagctaat atgtaccaat ctttgcatac taccgtgatc ggtccggcag
    29821 gaaatccggt agaaattcaa atccgaacac aggaaatgca tgaaatcgct gaattcgggg
    29881 ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa agtagaacca gatggtatga
    29941 cgaaacaatt aagctggttc catgagatac tcgaacttca agacgaaagc tatgatgctt
    30001 ctgaatttat ggaaggcgta aaaggagata tctttagtga taaagtctac gtcttcacac
    30061 caaaaggaga cgttactgag ttaccaaaag gatccggacc attggacttt gcatacagta
    30121 tccatacaga tatcggtaac aaaaccactg gtgcaaaagt aaatggcaaa atggtgcagc
    30181 ttgattacaa attgaaaaac ggagatatca ttgagatcat gacttctcca aattcatttg
    30241 gcccaagtcg cgactggttg aaattagttg ctactagcaa agcaagaaat aagatcaaac
    30301 gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa aggccacgaa tccgtggtca
    30361 aatgtattac agatctagga tttacgccta aagatatttt gacgaagaac aaactgcaag
    30421 aagcactcga tcgttttaat tatcaaacag aagatgatct ctatgcagct gtagggtatg
    30481 gagaagttag ccccttgacg atggccaatc gtctgactga aaaagaacgt aaagaacaaa
    30541 aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa tcagccgaaa aaagaacctg
    30601 acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca aggggtagaa aacttactaa
    30661 ttcgtatcag tcgctgctgt aatccgattc ctggtgatga tatcgttggt tatatcacta
    30721 aaggcagagg gatatccatt catcgtcgag attgtccgaa tgttcagcct gacaaaccaa
    30781 atgtagcaga acgtttgatt gaagtcgaat gggaagatac atcgaataca cgaaaagagt
    30841 atgatgcaga tttggaaatt tacggctata atcgttcagg cttattgaat gatgtacttc
    30901 aaacagtcaa tgcgctaacg aaaaatctca acagcgttga agcacggacg aataaagata
    30961 aaatggcgac gatccatttg acggttggta tccagaattt atcccaccta aagagtatcg
    31021 tggataaaat caaagcagta cctgatgtct acagtgtacg ccggacgaat ggataggagg
    31081 acagatatga gagcagttgt tcaacgggta agtaaagctg ctgtgtcagt cgatcagcaa
    31141 gaaattggaa aaattggcta cggcctactt gttttattag gcattcatga aaccgatacg
    31201 caaaaagatg tggactatct ggtaaaaaaa attgcacaaa tgcgtatttt tgaagatgaa
    31261 caaggaaaaa tgaatattag tgtagaagat gtgggaggac aaattttaag tatctctcaa
    31321 ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa gctttgtgga agccgcacga
    31381 ccagaaacag ctattccttt atacgaatca ttcaatgaag gaatcagaag tcgcggcatc
    31441 acagtcgcta ccggacaatt cggagcagat atgtcggttt ctctcgtcaa tgatggacct
    31501 gtaacgatca ttattgattc taaaaacaaa taaagtaatc tggttttcac tagtaaaaac
    31561 tatgaaacac gtcgcttaag ttagactgat aaactctaac ttaagtggct tttttgtctg
    31621 caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta agcttaaatt atacaagtta
    31681 ttttttatag gaggttgctg aagatgaaag aagtaccagt agtagatatc aaaatcacag
    31741 atttaaaaaa attgtatcaa aaaggataca acatgttgga ggagttacgc catgaagcgg
    31801 acgctcccgt cgtcaaagca aagattttca ataaagaagc tatcacgatc tacggatcat
    31861 cagcagcaaa agtattttat gatccaagga atttcaaacg aaaaggtgct atgccaaaat
    31921 tagtattgaa gacacttttt ggtcaaggtg gagtacagac tttggatgga gctgctcatc
    31981 accatcggaa aaatattttt atggatctaa tgacaccgga aagaatggaa gattatcatc
    32041 gtatcttaga taagaatctg acacaagcac ttgaagcaca gcatggtcaa tttgaactat
    32101 ttgatttaag taagatggtt ttctttacat ctatttgcga gtgggcaggt atcaatttat
    32161 cagcgatttc taaagatgag gtcgaaaaat tagcagaata tcaaatctct atgatcagcg
    32221 gaacgtttac ttctccgatt gatcacataa aaggtgtcga aaatcgcaaa aaatcagaaa
    32281 aatgggcgca aggcttgatt gaagaagctc gacaaaatcc tgtggctgga aaagaaaatg
    32341 tggcattata tgcttttgcc aatgccacag atttagatgg tcagctttta cctctggaag
    32401 tggcagctgt tgaattattg aacatcatcc gtccaacggt tgctctaact gtgtgggcgg
    32461 cattgatggg acatgcactt ttcagtagac cagatttgta tcagcaatta aaaaatgact
    32521 tttcgacgtt acaagatccg tttattcaag aaatgagacg ctattatcct ttcttcccaa
    32581 tgctacctgc gatttcgctg aaagaagtag aagtagatgg ttatcgtata ccagaaggca
    32641 gttgggttat tttagattta tatggaacag accatgatga acgaacagtt gaagcgccag
    32701 attcctttat gatcaaacgg tatgtaggga aagcaaaaga tatttcctat aaagaagaat
    32761 atgagatgat tgcacaaggc gggggaaatt ttcgacaaat gcatcgctgt gcaggagaat
    32821 ggatcactct tcatagtcta cgtgtgtttt ccgatcagct agtaaataag tttgagttct
    32881 ctgtacctga acaagattgg acgattccat tcaatcagtt tccgacttat ccgaatagcc
    32941 gagcgctact ttacaagaat tagattagca taaacttatc gaaaaaaagg aagatcaaac
    33001 agtgctgatc ttcctttttt catattacta taaattgata aggtcaattg atcaaaatcc
    33061 acgaaatgct tcatcaatgg tttgataatc ttcattggat aaatgcaaat ctaaagcttg
    33121 gacattgtca gatacttgct ctggacgctt agctccaggt ataactacag acactcgtgg
    33181 attcttcatg taccaagcta aaacaagttg cgcaggagtg gcttggtatc ttttagcaat
    33241 ggggcgaagt acatcgacag cggttaaaat ttctctgaaa cgttctcctt ggaaatctgg
    33301 atttcttttt cgaggatctc cttcaccaaa ttgtttttcc tcaccaagtt catattttcc
    33361 tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa ctgattttgt ttttttcaag
    33421 ataagggaat aattcttttt cagcctgccg atggatcaaa ctgtatttat cttctactac
    33481 atcgacatat ccatctgcat tcgcttcttt caattgttct aacgtgaagt ttgacacacc
    33541 gactgctcgg atttttcctg cttcttttaa ttcgtgcaat gtagcaactg attcattttt
    33601 tggtgtgctt tcatccggaa agtggatata aaaaatgtcg atgtaatcag tttgcagacg
    33661 ttttagtgca tcttccaccg attgtttgag aaactcagga gaattatcaa atgttcgccc
    33721 tttatttggt acatgagcag cttttgtagc gatgacgaca cgtgagcgat catattcttt
    33781 ttccttcagt acctcgccaa tcagttcttc ggaacggccg tttccgtaag cataagcggt
    33841 atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact acttgttttc ctgtctcatc
    33901 ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt gctcctaatc caagctgttc
    33961 tgcgtagact tgtgaatgtc cgattcttat ttctgccata gctgattcct cctttttgtc
    34021 tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt tttgtgaggg gaaatagtca
    34081 gatatctctt gactttgaga ctggttttta gtaggttata agtaatatcg aatgtcaatg
    34141 aaagagcgag taagtttttg aaactttaca agagaggatc atcgaggctg aaaatgatct
    34201 aaagtttcat tagcctaaag acactctgga gatggacgag tgaaaagccg tcccgcgtac
    34261 gagcgttatt cgtaagagga aagagaaatc tttcaaaatt aggtggtacc gtgtatgaat
    34321 ttcattcacc cttgttcatg atgaacaagg gtgatttttt tatttacata gctaagaaag
    34381 ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa atgatatttt gccaggcgaa
    34441 tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat tattcagaga ttatcagtat
    34501 aatgaaatgc gtacaccgat ttttgaacac tatgaagtga tatcccgaag tgtaggggat
    34561 acaacggata tcgtttcaaa agagatgtat gatttttatg acaaagggga acgccatgtg
    34621 acgcttcgac cagaaggtac agcaccaatc gttcgttctt ttgttgagca taaattgttc
    34681 ggcccagagt atgcgaaacc gttcaaaact ttttatatgg gaccaatgtt tcgctacgaa
    34741 cgccctcaaa aaggacggtt acgtcaattc catcaaatcg gagtagaagc atttggatca
    34801 gaaaaccctg caactgatgt ggagagcatg gtgatggcac ttgatttctt caaacagttg
    34861 gggatcacgc aaatccggct agtcatcaat tcattaggtg ataaagaaac gcgtcaagcc
    34921 tatcgtcaag cattgatcga ctatctttta ccttttgaat cagagctgag tgaagactct
    34981 aaacgccgcc ttcatgaaaa tccattacgc gtattggaca gtaaagacaa acgagatcaa
    35041 aaatttgtgg cagaagctcc atctatctta gattatctaa gcgagcctgc tcaaaaacat
    35101 tttgataccg ttgtttccat gctggatgca ttggctgttc cttatgaaat cgacagtaat
    35161 atggttcgcg gactagatta ttacacacat acgatttttg aaatcatgag tgacgcacca
    35221 aaaatggggg cacaagcaac gatttgcgca ggcggacgtt atgacaatct agtggaagaa
    35281 ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg gtatcgagcg attactcttg
    35341 actatggagg cagaggaagt agttatccct gcatttaatg agttggatgc ttacgtggtc
    35401 gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg tccaagcgat tcgaaacttt
    35461 ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa aagcgcaatt taagacagca
    35521 gataaagcga atgccaaatt agtattggtg atcggtgaag atgagcttgc tagtcaaacg
    35581 attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt ttccattaga agagatatat
    35641 gaacattttg atgaagtcta tgatgaaatg actttattcg agtaggagga aaaaaataaa
    35701 tggcacaaag aacgatctat tgcggattag tttccgaaca acaattagaa caaacagtta
    35761 cattaaaagg atgggtacaa aaaagacgag accttggggg agtaatcttt atcgacctac
    35821 gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga aatcaacaaa gaagcatggg
    35881 aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt gactggggaa gttagaagac
    35941 gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga attcgaagtg attgcaagtg
    36001 aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca aattgaagat gatcaagcaa
    36061 tcagtgacga aatacgtttg aaatatcgtt atttggatct gcgtcgtcca aaaatgacta
    36121 aaaacatcaa attaagaaat gcgacaacaa aagcgattcg tcattattta gatgataatg
    36181 actttctcga tatcgaaaca ccttacctag ggaaatctac accagaaggc gcaagagact
    36241 acctagttcc ttcacgtgtc catgctggac atttctatgc gttgccgcaa tctcctcaat
    36301 tgtttaaaca attgctgatg aatgctggat tcgaccgtta ttatcaaatc gttcgttgtt
    36361 tccgcgatga agatttacgt ggagaccgtc agcctgaatt tacgcaagta gatattgaaa
    36421 caacgttctt aacagcagaa gaaatccaaa cttacacaga gggattgatt gcgaaggtaa
    36481 tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc tcgtatgacc tatgatgaag
    36541 caatggctcg ctacggcagc gacaaaccgg atacacgttt tgatatggaa ttgatcgatc
    36601 taagcgatac agtcaaagaa gtagaattca aagtcttcca aatggctctt gaaaacggcg
    36661 gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg ctactcacga aaagacatgg
    36721 atcagttagg tcaatatgta ggacaattcg gagctaaggg gcttgcatgg ctgaaagtag
    36781 aagaagacgg attgaaaggt ccaattgcta aattcatggg agaagcaaca gaagcaatca
    36841 ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt tggcgcagat aaaagtgaaa
    36901 tcgtcgctgc tgcattaggt gctatccgga cacgtttagg aaaagaatta ggactaattg
    36961 atgaatcgaa attcaatttc ttatgggtaa ctgattggcc acaatttgaa ttttcagaag
    37021 aagaaggtcg atatgtctct gctcaccatc cattcacgat gccaaaagaa gaagatatcc
    37081 cgttattggc tgaagaccct gcaaaagtct atgcagaagc ttatgatatc gtcttgaacg
    37141 gttatgaact aggcggaggt tctatccgta ttcatactcg tgagcttcaa gaaaaagtac
    37201 tagaaactct aggctttaca aaagaacaaa tggaagaaca atttggtttc ttgttaacag
    37261 ctttagatta cggattccct ccacatggcg gtattgcatt aggattggac cgttttgcaa
    37321 tgttattagc cggagaagat aatattcgtg aagtcattgc ctttcctaaa aacggaaaag
    37381 cagcagatgt gatgagtgat gcaccaagta tggtttcgcc tttacaattg ttcgaattga
    37441 atattgatgt aacgaatata gaagaatagc cgataaaaag gtaaaaagga tttgtcgaat
    37501 acgcttcttt tgacaacctt gatttaattg aaaaacactt tataatgaag ccataacata
    37561 taaagcgggg cttttccatg aaaaaaacat tcgaaaattg ggcttatcat gattacacga
    37621 ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc agtcgcattg aatttctttt
    37681 atcagccagg acatatttat tcaagtggta ttactggtct agctcagatt ttgacgactt
    37741 tgtcaaaatc actgatagga ttcgaagtac cggtatcaac aactttgtat ttactgaata
    37801 tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa gtttacaatt ttcactttta
    37861 tcacagtcac tttgacctcc ctttgtatcc atattttacc ggaaacagtc ctatctaccg
    37921 atccaatcat ctgtgcgttg tttggggggg ctgtgatggg actaggtatt gggctagcgt
    37981 tgagaaacgg cctatcatcg ggcggtctag atatcgtgag tatcacgatt cgtaaaaaaa
    38041 caggaaagtc gattggttct atttcgatct acttcaatgc attgatcgtt tttgttgccg
    38101 gaattctatt tggctggcaa tatatgtttt acagtacgtt gtctattttc gtcagtggaa
    38161 aagtaactga tgtcgtttat actaaacaaa agaagatgca ggtaatgatc gtaacgaaac
    38221 atccagaaaa agtagtaaat gaaatccaaa actgtatgcg tagagggatc acgatcatca
    38281 atgaagcaga aggtgcttat aagcatgata agcagacagt attgatgacg atcgttacac
    38341 gatacgaact gcctctactt agagaagcaa tgaaagcttc tgatccacaa gcttttgtaa
    38401 gtattgcaga aaacgtccag atacttggtc gtttctatga ggatggcatt tagatcgagt
    38461 ttgacaaaaa ttcatgaaat actgctgtag acagacgttc gtttgtctgc agtttttttc
    38521 taccatagta gaatcagcaa agaaaaactg cttttttatt tgaaattttc ttaaagttga
    38581 aaaaaagcat gtttattttt ttaaatttat gggatgatag aaaaaaatag tagagaaagg
    38641 acacgattct acttgctatt ttcacttaat acccgtatat tacgaatgaa aaaagtttat
    38701 gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa aaaacagccg ctacatcact
    38761 gggtttgatg ggctccgttc attagctgtg gtgggtgtta tcttctatca ccttctgcca
    38821 actagtatga aaggcggcta tttgggcgtt ccgatttttt tcgtcgtatc tggttatttg
    38881 atcacggatc tgctgcggca ggaatgggaa caaaatggaa aaatcaatat ttggcaattt
    38941 tatgtcagaa gaatgaagag actctatccg gcacttgttt ttatgcttgt gacagcttcg
    39001 gcttatatca ctttgtttca gcgagggctg ttaaacaatc ttcgaggagt tgtggtcagc
    39061 agcttactgt atgtcaacaa ctggtggcaa atcaataacg gtttatctta tttcgatcga
    39121 tttgctaatg agtcaccgtt tacgcatatc tggtctttag cagtagaagg tcaaaactat
    39181 ttggtttggc cgatcttgtt tgtattgttg atggtatttg ttcgtaaaag aaaatggatc
    39241 ttttatactg tgttaggtac atccttcctc tccgccatct tgatgatgat cttgtataca
    39301 ccaggaggcg atccaacccg tgtttattac ggtaccgaca ctcgtctgtt ttctatatgg
    39361 ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt taaagaaaaa catcccgaaa
    39421 caagcgaaaa atattctgaa tatcgctgga ggaatctcgc ttttggcact gattctttgc
    39481 ttcttctttt tagatgatca ttacaatttc atctattacg gaggaatgct cctagtgagt
    39541 ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg gagcaagttt gaatcgatgg
    39601 ctgacaaatc cagtatttac ttggattggc aaacgaagct atggcattta tctgtatcag
    39661 tttccagtta tgatttttta tgaagcaaag gtgactgata ttgccgatca tgttttgttg
    39721 catactttag tggaaatcac attgattcta atcatcagtg aactttctta tcgatatgtg
    39781 gagcgtccgc tagcacgttt tgattatggt cgtacattcc aagtgatgaa aggatggttc
    39841 agcaaaccga tcatcagtaa gagcaaacca tgggttgttc caggcacatt acttgtagca
    39901 attgcactcg ttggtttcgt tacggcaccg aaaaacgctg taacagccga tcaaaaacaa
    39961 ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag aaaccagaaa caattcagaa
    40021 aacaccacta gttcggttga ccaagcgatc cttgataagt acgagttgtc caaggcacaa
    40081 gggaataagg cacaaaaatt agaactaacg gcatttggtg attcagttat gttggatgct
    40141 gcaacggatc tacaagaact ttatccaaaa gtagtggtag atggagatgt cggacgacaa
    40201 ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac aagatttgtt gaaagacact
    40261 gttctgatcg gactaggaac gaatggctca ttctcggaag ctcagtttga tagtgtgatg
    40321 gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc gagtaccgac gaagcgctgg
    40381 caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa aatacgacaa tatgacgctg
    40441 attgattggt acagctacag taatgaccat agtgactggt tttatgatga tcaagtccat
    40501 ccaaatcctg aagggatgac acattacatt cacttagtca gcgaagcctt gctaggagga
    40561 agttcaagta cgaacagcag tgagacaaac gtgacagaat gatagctaca aaaaacttca
    40621 ggcaaaaaca tttgtttttg cctgaagttt ttttatattt accgtgtttt taacattcat
    40681 atagattcag gaagcaaaac ggttgagtgt gtctgtaaat aacgttcttt ttgttttcgg
    40741 gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc ttcttgaaga aaatacttct
    40801 gcatggatca tcttaacagg tcttcttttt tgaagacgag tatatttagc accagtacca
    40861 ttgttatgtt cctctaatcg tctagaaaga tcggttgtat atccaccata aaatgtctga
    40921 tctttacaga ataatacgta aaaataatgt tcatttgcca tagagcatct cacgaatctc
    40981 tgcagtgtat tctccatcca tattgtaagt gatcaatggt ggagcgactt tgaatccgtc
    41041 taatttgcct tctttgattc cttcaactaa caaaatattt gcctcttttc caggttttgg
    41101 gtaaacaaat tggatccttt taggtgcaat tcgatagtct tccatgacct gaatgatttc
    41161 taagaaccga tcaggacgat ggaccatagt aaagcgtcca tttgttttta gtagcttact
    41221 tgaaatatcg atcacttctt ctaacgtcgt atgaatctca tgacgggcga ttgccaggtg
    41281 tttattaggg ttcgttttat ttgttggcag ccctttgaaa taaggtggat tacagacgac
    41341 taagtcacaa gaattatgtc gaacgacaga taagctgtct ttcagatcga tggtgtggac
    41401 agtcatttgt tcatttaaat ggttaagcgc gatactacgt cttgccatgt ctgctagacg
    41461 aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt ttacttaaaa aaagtccaac
    41521 tgcgccattt cctgcacaaa ggtcaacaat cttccctttt ttaggtacac gggaaaagtg
    41581 agcaagcagc acagcatcta aagaaaaaga aaacactttg gaactttgga taatcttgat
    41641 atcttctgcg tataattggt cgattcgttc gtcttcgtga agcatggatt ccctccaaaa
    41701 tgaaaaaaat agtcgtctgt attatactat ttttattaaa aagaaccaag gtggcttgtc
    41761 aaacctctat tttttatgca tactatgacc ataagaaggg aaaggaagag actatgtttt
    41821 atcgatttat gcgcggggta gttcgagtac tattagcctt agttaatgga aatgcccgct
    41881 atgagaataa agaagtttta ccgcaagatg agaattacat actagttgct ccccatcgta
    41941 cttggtggga cccattatat ctggcggtag ctgcagcacc caaggaattc agctttatgg
    42001 caaaagaaga actgttcaaa aatccagttc tgcgatttat attaactcga tccaatgctt
    42061 ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa aacacctgta aagattttga
    42121 aatcgacaaa tttgagtttg atcatgtttc ccagtgggac aagacatgct acagaactta
    42181 aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa aatcgtgcca gctgtatatc
    42241 aaggtccgtt gacacttggg gatctgttca agcgtcagag agtgacagtg cgtttcggcg
    42301 aaccaatcga cttatcagat atcaagaaaa cggataaaga aggtatggcg gagatcgaac
    42361 gacgaacaca agcagctttt gacaaattgg acaaagaagt gaaccctgat ttcaaatatg
    42421 aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg gtcttttgaa tctactgtcc
    42481 tgttcagttc agactttttc aatgaaaacg agggagagac gtcaagtctg ccctcttttt
    42541 gcgttccaat atgtaaaata gaagacaggt gtcatgtaat ggatcaaagt gttataataa
    42601 ttagaaggac attttttgag gtgattgaat gcgtttttta catacagccg attggcatat
    42661 cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag cgtcatgtac tatcttctat
    42721 actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg attgccggag acttatatga
    42781 taggagtgtc ccagctgttg atgccgtaga attatacaat gaattgatgg tcgattggaa
    42841 tttaaaggaa aagatcccga tttttgctat atcaggaaat cacgatagca gtacgagact
    42901 ttcagcgggt acgccatggt tcagttattc gaactatttt ttgcgaacac agctagcaga
    42961 agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc tttcttcctt actttgaacc
    43021 aattgcagcg agattatatt ttgaagatga caatatccga acgatcaagc aagcggtagc
    43081 caaggtgata gataaaatgc aggagctatt tgattcagaa aaaaaacaag tattgattag
    43141 ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa acgaaaatcg aagtaggcgg
    43201 gttggattcg atccctggtg aactacttac accgtttgat tatgtagcac taggacattt
    43261 gcataatcaa gctgctttga gacaggataa tgctcgctat agcggttccc cattgaaatt
    43321 ctctttatct gagatcaacc aaaaaaaagg cgtatggatc gttgacctga caacaggcct
    43381 ggagttgaat tttagggaga tcgaacccct gcatgatatt gaagaaataa cagcgagttt
    43441 caaagaattg ctggatcctg ccttttatca gtccgtcaat cgggagaatt acatctatat
    43501 ctatctcact gatagaacga tcatcccgaa tatgatgaac cagcttcggc aaatatatcc
    43561 tcgtattttg gggattgaac gggcaaacgg tcgagcagaa caaacaaagc gcaaacgaaa
    43621 agtactagaa atgaaagatc ctcaaaaatt agcagaagca ttttttagtg aaatgacgga
    43681 agagcagcta actgcaaacc aagaaaaatg gctcggagaa acgttgcaag aaatcatgga
    43741 aatggaatga tcaagaatga aaccgaaaaa attacaactt aaaaattttg gtccttttat
    43801 caatgagacc gtagattttt cacgtttgac agaagcaccg ctttttttga tcagcgggaa
    43861 gacaggagct ggcaaaacga cgatttttga tgggatcacc ttcgcacttt ttggtgaaac
    43921 ttccggaaga cttcgctctg gaaaagagat gcgttctttg tttgctacac cagacgaaga
    43981 aacaagcgtg actttttctt ttgaacatca gcagatgagc tatgaaatcg aacgaaaacc
    44041 agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa aaacaggcag ccaaagtaac
    44101 gttgaccatt tttgatggga aaggaaaaga aataaaacaa atcacaaaac gtacagaagc
    44161 agatcagttg atcagagaac tgatgaatct cgatgcgaaa cagttttctc aaatcgtttt
    44221 actaccccaa ggagaattcc gtaatttttt ggtttcatca agcagtgata aagagactgt
    44281 tttacgtcat ttattcggta ctcaattttt ccaacagttc aatgagcgat taaaagaaaa
    44341 agcaaaacaa cagcaacaaa aattggatca tttagagcaa gagctgcatc ttctgcaaaa
    44401 aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg tttgaagccg ttttagccca
    44461 atggacaaac catcaggcaa tactcgaaaa acaaatcacg gaagaaaaag aagctctaac
    44521 ggaacttcag gaaaaacaaa agcaactaga aaattcctac tatcgttttg aaagcttgaa
    44581 aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa aaggaattag ctgctcaaaa
    44641 agacgaaata gaggaaaaga aacgatggat tgggtattat gaatttacgc aacgattagt
    44701 cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa atagaactgt cacaaaaaag
    44761 tagtgagcaa acaaagaaac tagcgatgac tacgcagaat tatgaagagt ggcaaaaaaa
    44821 tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa gctgctcaaa aactgcaaaa
    44881 caaacagatg atggtgccaa ttgtcgaatc cttacgtagt aaaaaacaag acgcagaaca
    44941 attaacaatt tcattggata aagaagaatt gaatgccgag aagctgtatc aaaatctcgc
    45001 tatctatcag gaaagaactc gaattcttca agaaaattta ctggatcagg aaaaactgca
    45061 agaagatcgt cttgcttttg gacagttaaa atatctagat gaaaagcagc aagaaataga
    45121 aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata agagaagaac tcaaaaaagc
    45181 aactgaagaa ataacaaaaa atagtcagct attgaaagaa cagacagaac aagcagaaca
    45241 gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt cagctttttt tgcgtccagg
    45301 ggagccatgt cttgtttgtg gatcaacgga acaccccata caacaattaa aacacgaaca
    45361 gccaaataag gaagatatct taaaagtaga acaacaactg gcagaagctg agtctgctgt
    45421 agaaagaact cagcaaatca ttgccaaaag tgaagcacat gaaaataatc ttcaacaaca
    45481 attatcagat ttagaacaaa aaatcatggc aacgaatata caattggctg aacaagaaga
    45541 acacttgcaa caggctttga aaaaggcatt tcctgagata acagaacaaa aaacaaaaac
    45601 aactcttgta gtaatcgaac aatctttaga tagacgaaaa agcaagatgg ccaatgcaag
    45661 aatagagctg gaagaaataa gacaacaagc agaaaagctc gaacaacaat tagctgtcta
    45721 caaacagcag cagacagaaa aaaataatca gctccagcaa ctgcaaggag aaatcaaaag
    45781 tttagaacaa caattgcaag atacggatag taactgttta gaagaggaga tacgacgact
    45841 tgaaaaacag ttagaagaag actcgaatca actagctgtt gagcagaaag caggagtgca
    45901 attgttgcaa gatcttcata cgcttcggac acagcttgat cttcaacatg aacaaataga
    45961 aaaaatagat gaaaaaatag aaaaggaaca agaaagaata gctaaaaagt tagaaagcca
    46021 gtcgtatttt tcaacaattg aagaaatctg tgcatttgca caacagcaag cacaatataa
    46081 agaaaaccaa cgtacagtta cttcttatca tgaagagcaa ttagtgacag ctgaccggct
    46141 gcgtcaatta gaaaatatcc agctaactga gacattccca gatacagaag agatcagcca
    46201 acagttagaa gaaataagac gtatgatcga aataaagcaa gaaaagatat acggtttaca
    46261 agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt ctttcgattt atcacacaag
    46321 ccagacgaaa ttagatgagc ttacgcaatt acagcagctt tcgcaaacat tcaacggaga
    46381 aaatcctaag aagactagtt tggaacggta tgtgcttcag gtttatcttc aagaagtgtt
    46441 acaagtagca aatgatcatc tccaacgttt aacgaaaaat cgttatcaat ttgagctagc
    46501 ggataccatt ggcagttatc gagggaaaac cggattagaa atcaatatct atgatgatca
    46561 ggcaggtatg tctcgaagtg cgcataccct gtctggcggt gagagtttta ttgcagcact
    46621 ttctttagca ttagctcttg ccgatgtgat ccagacacaa gctggtggtg tagcaatcga
    46681 tgcattgttt attgatgaag gatttgggtc attagatgaa gaagctttgg aaatggcaat
    46741 ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc ggcatcatta gtcatgtaag
    46801 agaattgaaa gaacgagtat tacaacaaat aagaattgat acagaaggta gcggacaaag
    46861 caaaatacgc tatcaacttg gataaaaagg gagattggta actatgaaat ggagtattcc
    46921 agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa ggccgagtgt tatcggttgt
    46981 ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg ggcagtgaat tgtatatggt
    47041 tgatttggat ggtacagcaa aagagataga ttactgccaa tgtccctatt gggaggaaca
    47101 taaatattgt aagcatacag ttgctgtgga actttattta cggtcgaaaa atctatctcg
    47161 tatcatgaaa aaagaccagc caatgctaga accggtaaaa gcaacaagtg agggagaaat
    47221 cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat cctcaagcgg tgcaaccttt
    47281 gattattgaa taccaagtag aaacgattga gactaatcag tatcacccag agctttctat
    47341 tttggcactt tacttgcgta tcggttcatt ggcatcaccg aaaaaaacat atatcgtaaa
    47401 aaacatctat gattttttac aagcttacac agaaaaagaa acttacactg ttaataaaca
    47461 gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa gatcaaaaaa tactcacgca
    47521 tcttgcagga agtgctcaga cgcatcaatt attaggtacg aacggcttac aagtcaaagg
    47581 aaaactagat aaaagatatc tgcttctccc agtagaacaa gcccgcttcc tgttagagca
    47641 gatgaatcag actacacgtt tgcatctgca gataaatgaa caaaacgatc aaggaataca
    47701 attttccgat caaaacaaac ctttatcatt caaagtggaa aaatttggag aagattattt
    47761 gctgcaagca ttgaatgatt ttgatttttt ctttatgcat tatcagtggg gagttatcca
    47821 agggacattt tattctctga cgaaatatca acaaacggtt tatcaaactt ggaaacaatt
    47881 gattcgccga ttggagaaac cagaagtagt gttcaagaaa aaagaattac cgtctttgtt
    47941 taaagagatt atccctctgc tgtcagagat cggcgacgta gctattgccc ctgcagtaga
    48001 agaggaagta gcagatatcc ccgtcgaatt tattttcttt ttccgaaaag caaaaggaaa
    48061 aatccaagct cgagtcgatt tcgtctatgg cgaagtcatc tattcgactg acccgaagca
    48121 tgaggtctcg acagaacagg cttttcaggt gttacgtgac acagtagaag agaaacgagt
    48181 acttgatcta ttcagaatgt atcgctacca gaaaaatgaa actggttatg aacgtccatt
    48241 gccaagcggg gaagaactat atgccttttt ccgcacagaa ctatctgtct tccgtcagtt
    48301 tggtgaagtc agacttggaa gaaaattgcg agagttgtat ttagatgcgc ataaacatca
    48361 accgaaaatc gaagtaaccg agaccggttc atggctcgat attcgattcg atgtgacagg
    48421 gatagaggag caagaaatcg atcatgtcct gcaaagcttg ctgagaaatg atgcttttta
    48481 tacattagaa aatggtcagg ttctttcttt tgattcagaa gaatttcaac aaacaagcca
    48541 agtgttgcaa caattacggg aatcgatacg tacagaagaa ggaacgatcc atgtacctaa
    48601 aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc aatgctactt ttagtgaatc
    48661 gttccaaacg atggtacaag atctcattca tccagaaaga taccaggcac agcttcccaa
    48721 aggattgaat gcaacgatga gagattatca aaagcaaggt tttcgatggt tgaagatgtt
    48781 aggtcattat cagtttggcg gtattttagc cgatgaaatg ggacttggga aaacactaca
    48841 gacaattgcc tttttacttt cggaaaaaga agaacggaaa agcttctctg ctttgatcgt
    48901 agcgcctgcg agcttaattt acaactggca ggcagaggtg agaaaattcg ccccttcttt
    48961 aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa gaattactgg ctaaagacac
    49021 agatatccga gtgacttctt atgccagctt aagacaggat ctagctaatt atcagtcgca
    49081 aaaaattgat tatttgattc ttgatgaggc acaaatggtc aaaaatagca gtacgaaaac
    49141 tgcacaagca ttgagagaat tagctgtacc tcagcggttt gcactgagtg ggacaccaat
    49201 cgagaataat ttagaagaat tgtggtcatt gtttgcaacg attatgccag gatttttccc
    49261 gactaaaaca aaattcaggg aacttgccgc agaagaaatt gcgcaaatga ttcgaccgtt
    49321 tattttacgg cgagataaac aaactgtgtt gaaagacttg ccggaaaaaa cagagatgaa
    49381 tctatattct gcacttacag aagaacaaaa aactgtttat ttagcttact tgcgtcaaat
    49441 gcgtgaagaa atcacatcaa tggattctga agcattcaag aaaaaccgga tcgggatact
    49501 tgctggtctg acaagactgc gacaaatttg ctgcgatcct cgtctgttta ttgaagatta
    49561 ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta ctggtagctg ccaaagagaa
    49621 caaacgaaga gttttgctgt tttctcaatt tacagggatg ctgactatct tgcaagaaga
    49681 gttagccgag ctagggatct cgacatttta tttaagaggc agtacgaaac cacaagatcg
    49741 gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat gtttttctga tttccttaaa
    49801 ggctggggga actggattga atctcacggg agcagatacg gtcatcttgt atgacctttg
    49861 gtggaatcct gccattgaag aacaagctgc tggacgtgca catcggatcg gacaaaaaaa
    49921 tgtggtagaa gtgtggcgta tgatctctga aggaacgatt gaggaacgca tggattcact
    49981 ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa ggtaatgaag aacagttgac
    50041 gaaactgact gaagaagaca tccgcatgat tttaagtgta ggagaaatcg aggagtaaga
    50101 gactcgaaaa agcgttcagt aatgggtaag aaagcctttc taaagaagcg attgtttatt
    50161 tgatttaaaa aatagcaagg aggctgggat tccattttat cccagcttcc ttgctatcat
    50221 ttttttattt ctatttttaa aggttataca aagattgtct tcattgtctc taacagctga
    50281 tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt caattttgcg ttctcgatgg
    50341 ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta gaacatcatt gtcgtaatta
    50401 tcgccaacgt ataaggtctc ttctggaagc atatgaaatt ctttctcagc tagctgaaaa
    50461 atctcttttt ctggtttttg gaaacctgtt gcttgagaaa tgagcatatt gcgggaagga
    50521 atccaattgt tcaattgaag ttgcttcagt ttttttgtct gatggtcagt cggcccattt
    50581 gtgataattc ctaatgggac attcttttcc ttcaagaaat cgagggtttt tttgacctcc
    50641 tcatgcaagc agatattatc aagttcttcc tcgtaaattt tttgaaataa gaggccatct
    50701 tcttccgtaa tatgagggta gtctaaatct tttagtgatt ggctgatccg atgtgctcgc
    50761 atatattcta gtgtccaatc tcctgccatt acttttggga agttttcatc actatgatgg
    50821 cggaaccgga tatatagtgg atgcatatct gcatctgaaa caagcggaac gactcttttg
    50881 accgcgtttc gaaatggctg ctgctgatca tacatcgtat catcaacatc aaacacaact
    50941 gatttaatca aaattttaca cgcctttcgg ttttcattga ttttttcaca aatccttgac
    51001 tattgtaaca gaaaaaattg tctaaaaaag ctgataaata aaggtttttc ttactatatt
    51061 tctatttcct tgacagaata aggtttttat atttcagttt ttttcactaa aaatcgtgaa
    51121 acacgtcaat aagtttgatg aacaaattaa tcattatggt agaagtcgat tgatttattt
    51181 taatgcaatc tctgtggaat tttcgaaaga tttatttttt taatacagtc tcaatataac
    51241 tattcaaaca taaaataacg ttatttgatt tatttgttta tagtaaattt tatttagtaa
    51301 tcattgcttt aaaatactac gcttatataa cagagaaaat aagcgttata ataaagaaca
    51361 gtattattta aaatgacaga aaacattact attaaagaaa taaaaaacat aaaaaatctt
    51421 aagaaatcgg tttcatttag cttttgagat aaaataatag tacagtttta tacgctgttt
    51481 catatgttta gaaaatttga attagatttg aaaactctaa tttttaaatg ataaaaaaag
    51541 cgagaatgct ggttttactg tatattaacc ttagataact ttcatttttt taaaaaaatt
    51601 atgaaaaaaa ggtagctatt taaaagttga ttatgtataa tagaaacaga tgggagatta
    51661 ttatgatctt ctgttacaaa aaagtgattc ttatcacgaa aaggagtggt gcacgttgtt
    51721 aacattatat acttccccaa gttgtacttc ctgcagaaag gctcgtgcgt ggttgcaaga
    51781 acatcagatt ccatttgttg aacgtaatat tttttcagaa ccattgaaca gttctgaatt
    51841 aaaagcgatt ttacaaatga cagaagacgg aacagaagaa atcatctcga cacgttccaa
    51901 agtattccaa aaactgaaca tggatttaga tgatctgccg ttacaagaat tattggaact
    51961 tgtgcaaaac aatcctggat tgcttcgccg tccaatcatg attgatgata aacgtctgca
    52021 agttggtttt aatgaagatg aaattcgtcg gttcctaccg cgcgatgtac gacaattaga
    52081 attacgtcaa gcacaattga tggctggatt atagaaggat aatacgaaac ttggaaaaga
    52141 ctattacaaa gatagttttt ccaagttttt ttgtttttac aaaaagtatt cttgattaga
    52201 tgtataaaaa ggtagtagaa gatgatgatt gcacgaaaaa tagagaggga aaattagctg
    52261 aaaagtcggc tatatagtat tcgtctgcca aaaatgttat agttaaataa gatagcttga
    52321 aaggttgaaa aatccgctgg ttttattaaa ttcgcttaac agcgagattt tttttcttta
    52381 catttaagct gatttcgcta caatgaatct atattaaaca ttgtggcaaa gtgaggtgta
    52441 gcaaaatgga aatggaacat attaatgaaa atacgatccg tgtactaatt ggtcatgaag
    52501 atttagagga acggggcgtt tcatttttgg atttacttgg caatcacaaa gaaatcgaaa
    52561 atttctttta tagtattttg gaagaagttg atatcgaaga ggagttccga ggaagcgaag
    52621 ctgtcacttt ccaagttttg ccaaaaggag acggattaga actgtttatc agtaaaaatc
    52681 ttccggatga agaaatttct caatcagaag attctactgt tgattcagaa gatgtgagtg
    52741 actttcttcg tcagcagatt attggcagcg atccggagga agaattatct ggaagcgccc
    52801 tagaagaaca ggaaagacaa gcaacttttg cttttgaaga ttttgaacaa gtgatccaac
    52861 ttgcaacaga tgtcgaacta gagtctgctt ggactgattt gtatttattc gaagagcgct
    52921 attacctagt cgttcacttc tggatggaaa atctcaacca agcggatgta gagaatcaga
    52981 ttgctcgaat tttggagttt gctgaaaaga gcgatcgtac accagaaaca ttgaatgaat
    53041 atggacaatg tctgatggcg cgtaatgcta tcgagcgaac gaaattttat tttgtataaa
    53101 tcagcattat agtaagagac tgtgacaaaa attgtgtcgc agtctttttt tcgtataaat
    53161 gtgttcaaaa gcttgcatct gcggtaacaa gcccaaccaa acgaaaaata ttgggaacta
    53221 tttttgttta gctgttctta ttacttgatg cagaatagct ttttcacgcc ctcttttttc
    53281 gtgtaaataa attcttagac gtaaataagt tcagagggag aaaaatgctg cttgcaatga
    53341 atgaatataa taagtgctgt tttgctaaac atgcagaaaa aggaaagaaa tattattgtc
    53401 gtggctgtcg aaaaagagtg attttgaaaa agggaaagaa aaaatgtgct cattttgccc
    53461 atcaaaaatc agataactgt tcggtcttta gtgaaagaga atcaaaagag cacttacagt
    53521 taaaggaatg cttcatggat tggctgggac agtcagtaga accagtattt ttggaagcct
    53581 atttgccgag gttgcggcaa aggccggata ttttgttggc gaatctagca atagaaatcc
    53641 aatgttctag actgtctcac cagagattta ttgaaagaac ccaaaattat ttgaataaca
    53701 gttaccaagt atggtggata cttggtaatt cttttcttgg acaatcgcaa ttctcattga
    53761 tagaaaaaag ttgctgctac tataatagaa aaagaggagt gcattgctgg aaagctgatc
    53821 tcaagaaaca aaagctttat ttgtatcatc atattacaga gactgtatca gggcatattt
    53881 ccttttgcag tagctgctgg actttttcta gtagggacct taaagaaata ttcactagta
    53941 acgaaattaa aatgaaccaa atgaaaaaaa tagaaaaagt gagtgaagat gggaagaaat
    54001 ggctgacacg ccaacttatt cacaagcaaa agaatacagt atccatacaa gaacaatgct
    54061 acttgcgtca taaacatctt ttgcatctat catcgtggat ctatcaaaaa agtcggtttt
    54121 tcttttattt acaagaacag gtttttcttt atcgaatgtt gtacgaagaa gccttggaaa
    54181 accagaaagt tcctgatttc aactcatggc tttgccaaat aaaagaacat aaaagggaat
    54241 ggctttttcc tatgattgat gaagagatgg tctatcagca gttttttaac gaatgcatac
    54301 acttgtcttc tttgaaaaaa tagtaagtat aaaaataggc taggaatcgg ttttctatgt
    54361 aaaacaagat ttagttatgc taaaattgat ggaagcagac acatgaatga gtagaaaagt
    54421 tagatgctgt gacatgtgga tgttagacta tgatctattt tgatagatag agctaaggga
    54481 agaaaaggag tggatttcat ggaagtaaag cagttgccaa aacgagaaga attgcctgaa
    54541 aatttaactt gggacttgac caagatcttt tcaagcgacc aagagtttga tgagaaatat
    54601 ttggaattat cagaagagtt aaaacaatct gaaaaacaca aaggaacact tgatcaaggc
    54661 gcttctcaat ttttaaatgc gattgaattc gtattgaggg tttatcgcca aactgaagtc
    54721 atttatgtat atgcgcacct taaaaacgat caagacactg gaaatacaga ttaccaagcg
    54781 ctttatgcaa gagcaagcag tctgttttcg aaagttagtg aagccgtttc ctggtttgaa
    54841 ccagaaatat tgcaattgtc agatgaccag atttggcaat atttcaaaga agaaccaaaa
    54901 ttggaagtct atcgccatta tatccagcaa atagtagata atcgagccca tgtcttatct
    54961 gctgagcagg aatctcttct tgctggagca ggtgaaatct ttgatgcttc aagtgataca
    55021 tttgctgttt tgaataatgc agatctagtt tttccaacga ttgaaggaga aaatggtgaa
    55081 atagtccaat tatctcatgg cgtgtatggt cagttgctag aaagcacgga tcgaagggtg
    55141 cgcgaagcag catttaaggg gttgtacagt gtttacgaac aatttagaaa tacatttgct
    55201 tctactttag gcacacatat aaaaggacat aattttaaag cgaaagtccg taattacagc
    55261 tctgccagag aagcgtcttt gagcaataat catattcctg aaagtgtata cgatactttg
    55321 gtagacgtgg taaacaagca tttgcctttg ttacatcgat acatggaatt acggaaacgt
    55381 ttattagaag tggaaaaact gcacatgtat gatctttata caccggtctt aggggaagct
    55441 ccaattacct ttacgtacga agaagcaaaa gaaaaagctt tagaagcact gaaaccaatg
    55501 ggtgaagaat acatggccat cgtagaaaaa gcattctctg aacgttggat cgatgttgtc
    55561 gaaaataaag ggaaacgaag cggtgcttat tcttcgggaa gctatgacac aaatccatat
    55621 attttattga attggcatga tacgctggat cagctattta cgcttgtcca cgaaatggga
    55681 catagtgttc atagttattt cactcgttcg aaccagcctt atgtgtacgg cgactactcc
    55741 atctttttag cagaaattgc ttcgacaacg aatgaaaata tcctaacgga gtatttattg
    55801 gaaacagaaa aagaccctcg tgtacgggct tatgtactca accattactt ggatgggttt
    55861 aaaggaacag ttttccgcca gacacaattc gctgaattcg agcatttcat gcatacggaa
    55921 gatgaaaaag gtgtgccatt gactagtgaa tacctaagtg atagttatgg taaattgaat
    55981 gcaaaatatt atggtccagc agtcgaagaa gacccagaaa ttaaattcga atggtcacgg
    56041 ataccgcatt tttattataa ttactatgtt ttccaatact cgactggctt ttctgctgct
    56101 tcagcactgg cgaagaaaat actaaaccag gaaccagagg cactagagaa ctacttggct
    56161 tacctaaaag caggtaacag cgattatcct gtggaagtaa tgaaaaaagc aggagttgat
    56221 atgacacagg ctgcatatat tgaagatgca atgtcgatgt ttgaacaacg tctaaatgaa
    56281 ttagaagaat tgatcgatcg tttataaggc tttctatttt tgattttctc gaatagaaac
    56341 gaaaaaaata cgtcggctct cttgtaaggg agtcgacgta ttttttta
//
LOCUS       DAIGUC010000014        54513 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.014, whole genome shotgun sequence.
ACCESSION   DAIGUC010000014 DAIGUC010000000
VERSION     DAIGUC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.014"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            262..570
                     /gene="rpsJ"
                     /locus_tag="NOB46_000834"
     CDS             262..570
                     /gene="rpsJ"
                     /locus_tag="NOB46_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCI1057795.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            601..1230
                     /gene="rplC"
                     /locus_tag="NOB46_000835"
     CDS             601..1230
                     /gene="rplC"
                     /locus_tag="NOB46_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCI1057796.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            1258..1881
                     /gene="rplD"
                     /locus_tag="NOB46_000836"
     CDS             1258..1881
                     /gene="rplD"
                     /locus_tag="NOB46_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCI1057797.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            1881..2171
                     /gene="rplW"
                     /locus_tag="NOB46_000837"
     CDS             1881..2171
                     /gene="rplW"
                     /locus_tag="NOB46_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCI1057798.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            2210..3043
                     /gene="rplB"
                     /locus_tag="NOB46_000838"
     CDS             2210..3043
                     /gene="rplB"
                     /locus_tag="NOB46_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCI1057799.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            3086..3364
                     /gene="rpsS"
                     /locus_tag="NOB46_000839"
     CDS             3086..3364
                     /gene="rpsS"
                     /locus_tag="NOB46_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCI1057800.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            3387..3734
                     /gene="rplV"
                     /locus_tag="NOB46_000840"
     CDS             3387..3734
                     /gene="rplV"
                     /locus_tag="NOB46_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCI1057801.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            3748..4404
                     /gene="rpsC"
                     /locus_tag="NOB46_000841"
     CDS             3748..4404
                     /gene="rpsC"
                     /locus_tag="NOB46_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCI1057802.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            4407..4841
                     /gene="rplP"
                     /locus_tag="NOB46_000842"
     CDS             4407..4841
                     /gene="rplP"
                     /locus_tag="NOB46_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCI1057803.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            4831..5019
                     /gene="rpmC"
                     /locus_tag="NOB46_000843"
     CDS             4831..5019
                     /gene="rpmC"
                     /locus_tag="NOB46_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCI1057804.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            5044..5310
                     /gene="rpsQ"
                     /locus_tag="NOB46_000844"
     CDS             5044..5310
                     /gene="rpsQ"
                     /locus_tag="NOB46_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCI1057805.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            5368..5736
                     /gene="rplN"
                     /locus_tag="NOB46_000845"
     CDS             5368..5736
                     /gene="rplN"
                     /locus_tag="NOB46_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCI1057806.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            5773..6081
                     /gene="rplX"
                     /locus_tag="NOB46_000846"
     CDS             5773..6081
                     /gene="rplX"
                     /locus_tag="NOB46_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCI1057807.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            6109..6648
                     /gene="rplE"
                     /locus_tag="NOB46_000847"
     CDS             6109..6648
                     /gene="rplE"
                     /locus_tag="NOB46_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCI1057808.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            6667..6852
                     /locus_tag="NOB46_000848"
     CDS             6667..6852
                     /locus_tag="NOB46_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCI1057809.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            6888..7286
                     /gene="rpsH"
                     /locus_tag="NOB46_000849"
     CDS             6888..7286
                     /gene="rpsH"
                     /locus_tag="NOB46_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCI1057810.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            7318..7854
                     /gene="rplF"
                     /locus_tag="NOB46_000850"
     CDS             7318..7854
                     /gene="rplF"
                     /locus_tag="NOB46_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCI1057811.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            8015..8371
                     /gene="rplR"
                     /locus_tag="NOB46_000851"
     CDS             8015..8371
                     /gene="rplR"
                     /locus_tag="NOB46_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCI1057812.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            8392..8892
                     /gene="rpsE"
                     /locus_tag="NOB46_000852"
     CDS             8392..8892
                     /gene="rpsE"
                     /locus_tag="NOB46_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCI1057813.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            8907..9086
                     /gene="rpmD"
                     /locus_tag="NOB46_000853"
     CDS             8907..9086
                     /gene="rpmD"
                     /locus_tag="NOB46_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCI1057814.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            9130..9570
                     /gene="rplO"
                     /locus_tag="NOB46_000854"
     CDS             9130..9570
                     /gene="rplO"
                     /locus_tag="NOB46_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCI1057815.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            9570..10865
                     /gene="secY"
                     /locus_tag="NOB46_000855"
     CDS             9570..10865
                     /gene="secY"
                     /locus_tag="NOB46_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCI1057816.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            10927..11574
                     /locus_tag="NOB46_000856"
     CDS             10927..11574
                     /locus_tag="NOB46_000856"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCI1057817.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            11765..11983
                     /gene="infA"
                     /locus_tag="NOB46_000857"
     CDS             11765..11983
                     /gene="infA"
                     /locus_tag="NOB46_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCI1057818.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            12016..12132
                     /gene="rpmJ"
                     /locus_tag="NOB46_000858"
     CDS             12016..12132
                     /gene="rpmJ"
                     /locus_tag="NOB46_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCI1057819.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            12150..12515
                     /gene="rpsM"
                     /locus_tag="NOB46_000859"
     CDS             12150..12515
                     /gene="rpsM"
                     /locus_tag="NOB46_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCI1057820.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            12543..12932
                     /gene="rpsK"
                     /locus_tag="NOB46_000860"
     CDS             12543..12932
                     /gene="rpsK"
                     /locus_tag="NOB46_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCI1057821.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            13012..13950
                     /locus_tag="NOB46_000861"
     CDS             13012..13950
                     /locus_tag="NOB46_000861"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCI1057822.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            13978..14358
                     /gene="rplQ"
                     /locus_tag="NOB46_000862"
     CDS             13978..14358
                     /gene="rplQ"
                     /locus_tag="NOB46_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCI1057823.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            14630..15469
                     /locus_tag="NOB46_000863"
     CDS             14630..15469
                     /locus_tag="NOB46_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI1057824.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            15445..16314
                     /locus_tag="NOB46_000864"
     CDS             15445..16314
                     /locus_tag="NOB46_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI1057825.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            16304..17101
                     /locus_tag="NOB46_000865"
     CDS             16304..17101
                     /locus_tag="NOB46_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI1057826.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            17304..18050
                     /gene="truA"
                     /locus_tag="NOB46_000866"
     CDS             17304..18050
                     /gene="truA"
                     /locus_tag="NOB46_000866"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI1057827.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(18383..21052)
                     /locus_tag="NOB46_000867"
     CDS             complement(18383..21052)
                     /locus_tag="NOB46_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HCI1057828.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(21290..21478)
                     /locus_tag="NOB46_000868"
     CDS             complement(21290..21478)
                     /locus_tag="NOB46_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCI1057829.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            21748..22110
                     /locus_tag="NOB46_000869"
     CDS             21748..22110
                     /locus_tag="NOB46_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1057830.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            22162..23844
                     /locus_tag="NOB46_000870"
     CDS             22162..23844
                     /locus_tag="NOB46_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCI1057831.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            23961..25997
                     /gene="recG"
                     /locus_tag="NOB46_000871"
     CDS             23961..25997
                     /gene="recG"
                     /locus_tag="NOB46_000871"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCI1057832.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            26046..27047
                     /gene="plsX"
                     /locus_tag="NOB46_000872"
     CDS             26046..27047
                     /gene="plsX"
                     /locus_tag="NOB46_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCI1057833.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            27169..27411
                     /gene="acpP"
                     /locus_tag="NOB46_000873"
     CDS             27169..27411
                     /gene="acpP"
                     /locus_tag="NOB46_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI1057834.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            27679..28683
                     /locus_tag="NOB46_000874"
     CDS             27679..28683
                     /locus_tag="NOB46_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057835.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            28684..29628
                     /locus_tag="NOB46_000875"
     CDS             28684..29628
                     /locus_tag="NOB46_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057836.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            29628..30590
                     /locus_tag="NOB46_000876"
     CDS             29628..30590
                     /locus_tag="NOB46_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057837.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            30617..31531
                     /locus_tag="NOB46_000877"
     CDS             30617..31531
                     /locus_tag="NOB46_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057838.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            31557..33338
                     /locus_tag="NOB46_000878"
     CDS             31557..33338
                     /locus_tag="NOB46_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1057839.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            33686..34372
                     /locus_tag="NOB46_000879"
     CDS             33686..34372
                     /locus_tag="NOB46_000879"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCI1057840.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            34392..37973
                     /gene="smc"
                     /locus_tag="NOB46_000880"
     CDS             34392..37973
                     /gene="smc"
                     /locus_tag="NOB46_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCI1057841.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            37982..38791
                     /locus_tag="NOB46_000881"
     CDS             37982..38791
                     /locus_tag="NOB46_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1057842.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            38802..39800
                     /gene="ftsY"
                     /locus_tag="NOB46_000882"
     CDS             38802..39800
                     /gene="ftsY"
                     /locus_tag="NOB46_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCI1057843.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            39987..42254
                     /gene="gshAB"
                     /locus_tag="NOB46_000883"
     CDS             39987..42254
                     /gene="gshAB"
                     /locus_tag="NOB46_000883"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HCI1057844.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(42343..42795)
                     /locus_tag="NOB46_000884"
     CDS             complement(42343..42795)
                     /locus_tag="NOB46_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HCI1057845.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            42945..43895
                     /locus_tag="NOB46_000885"
     CDS             42945..43895
                     /locus_tag="NOB46_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI1057846.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            43888..44847
                     /locus_tag="NOB46_000886"
     CDS             43888..44847
                     /locus_tag="NOB46_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI1057847.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            44844..45599
                     /locus_tag="NOB46_000887"
     CDS             44844..45599
                     /locus_tag="NOB46_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1057848.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            45622..46575
                     /locus_tag="NOB46_000888"
     CDS             45622..46575
                     /locus_tag="NOB46_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1057849.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(47219..47515)
                     /locus_tag="NOB46_000889"
     CDS             complement(47219..47515)
                     /locus_tag="NOB46_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HCI1057850.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            47870..48226
                     /locus_tag="NOB46_000890"
     CDS             47870..48226
                     /locus_tag="NOB46_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI1057851.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            48236..49135
                     /locus_tag="NOB46_000891"
     CDS             48236..49135
                     /locus_tag="NOB46_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCI1057852.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            49652..50383
                     /locus_tag="NOB46_000892"
     CDS             49652..50383
                     /locus_tag="NOB46_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI1057853.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            50528..52555
                     /locus_tag="NOB46_000893"
     CDS             50528..52555
                     /locus_tag="NOB46_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCI1057854.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            52663..53760
                     /locus_tag="NOB46_000894"
     CDS             52663..53760
                     /locus_tag="NOB46_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI1057855.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            54067..>54513
                     /locus_tag="NOB46_000895"
     CDS             54067..>54513
                     /locus_tag="NOB46_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057856.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        18213 a         9637 c        11691 g        14972 t
ORIGIN      
        1 aaaagagtca gtattttcta aatgaaactt tatgaaaaca aaatgttttt tacaagaaaa
       61 agccttgctt tgtgagttta tatatattat aatgacaaag gtgcgtttac tttagtgaat
      121 tgcacagacg taatcagaat gatttcgtcg gctaagaaac gagaggttgc gacacgcccg
      181 gacgctttgc cacgaacgag cgtgacggaa attttcgtgg agctatgtct acttttcaaa
      241 ataggcgaag gagggaacaa gatggcaaaa caaaaaattc gtatccgttt aaaagcgtat
      301 gaacaccgta ttttagatca atcagcggat aaaatcgtgg aaactgcaaa aagaactgga
      361 gctagcgtgt ctggtccaat tccattacca actgaacgca gtctttacac aatcatccgt
      421 gcgactcata aatacaaaga ttcacgcgaa caattcgaaa tgcgtacaca caaacgtctt
      481 atcgacattg tgaacccaac accaaaaact gttgatgctt tgatgaagct agacttacca
      541 tctggtgtaa acatcgaaat caaattataa aactaaaaca aaaataatgg aggtgtactc
      601 atgaccaaag gaatcttagg gaaaaaagtg ggaatgacac aaatcttcac tgaatctggt
      661 gaattaattc cagtaactgt tgtagaagct actccaaacg tagtactaca agtgaaaaca
      721 atggaaacgg atggctacga agctattcaa gttggttacc aagatatgcg tgaagtttta
      781 tcaaacaaac ctgcgaaagg tcatgttgca aaagcaaaca cggctcctaa gcgcttcatt
      841 cgtgaattca aaaatgttga gctaggagaa tatgaagtag gaaaagaaat tacagtagat
      901 gttttccaag caggagacat tattgatgta acaggtacta cgaaaggtaa aggattccaa
      961 ggggttatca aacgccacgg acaaagccgc ggaccaatgg ctcacggttc tcgttaccat
     1021 cgtcgtcctg ggtcaatggg tccagttgca cctaaccgtg tatttaaaaa caaacgtctt
     1081 gctggccgta tgggtggcaa ccgcgtaact atccaaaact tggaagttgt acgtgtcgat
     1141 gcagaaagaa atgttatctt gatcaaaggt aatgttcctg gagctaaaaa atctttaatt
     1201 actatcaaat cagctgtgaa agctaaataa ttgtaggaag aaaggaggaa ctaaggaatg
     1261 ccgaatgtag cattattcaa acaagatgga agccaaaacg gtgaaatcac acttaacgaa
     1321 gaaatcttcg gaattgaacc taatgaaagt gttgtttacg atgcaatcgt aatgcaacgt
     1381 gcgtcattaa gacaaggaac acacgcggtt aaaaaccgta gcgctgttcg cggcggcgga
     1441 cgtaaaccat ggcgtcaaaa aggaacaggt cgtgcacgtc aaggatctat ccgctcacca
     1501 caatggcgtg gaggtggcgt agtctttgga ccaacaccac gttcttacag ctacaaactt
     1561 cctaaaaaag ttcgtcgttt agcaatgaaa tctgtattgt cagaaaaagt tgctgaaaac
     1621 aacttggtag caatcgaagg cttgaacttc gacgcaccaa aaacaaaaga attcaaacaa
     1681 gttcttgcta acttatctat cgactctaaa gtattggttg ttctagaaaa aggtaacgac
     1741 tttgctgctt tatcagcacg taacttacca aacgtttctg tagtaacttc tgataatgtg
     1801 agtgtgctag acgttgtatc aaatacaaaa gtgttagcaa cacaaactgc tcttactcaa
     1861 attgaggagg tgcttgcata atgaacttac tagacgtaat caaacgccca gtgatcactg
     1921 aaaaatcaat gcttgccatg gatgacaaga aatacacttt tgaagtggac actcgcgcaa
     1981 acaaaacttt agtaaaacaa gcggtagaag ctgcttttga cgttaaagtc aaaaacgtga
     2041 acatcgtgaa cgtacgtgcg aaattcaaac gtatgggcaa atatgcagga tatacaaaaa
     2101 aacgtcgcaa agcgatcgtt acattgactg aagattcaaa agaaatccaa ttattcgaag
     2161 ctgctgaata agcactaata gataactcat taaattagga gggaaaaacg tggcgattaa
     2221 aaagtacaaa cctacctcaa atggtcgtcg taacatgaca ggttctgatt ttgctgaaat
     2281 cacaacatca acacctgaaa aatcattgtt acaaccattg aaaaaccatg ctggacgtaa
     2341 caacaacggc cgcatcactg tacgtcatca aggtggcgga cacaaacgcc aatatcgcgt
     2401 gatcgacttc aaacgtaaca aagataacgt tgttgcaact gttcaaacga tcgaatatga
     2461 tccaaaccgt tcagctaaca tcgcgttagt acactatgaa gatggagtga aagcttacat
     2521 cttagcacct aaaggactag aagtgggtat gaaacttgtt tcaggtccag aagcagatat
     2581 caaagtcgga aatgctcttc cattagaaaa cattccagtt ggtactgtta tccacaacat
     2641 tgaaatgaaa cctggtaaag gtggacaatt gatccgttct gctggtacaa gtgctcaagt
     2701 acttggtaaa gaaggcaaat acgtattgat ccgcttgaac tctggtgaag ttcgtatgat
     2761 cttagctgca tgccgtgcta caatcggttc tgtaggtaac gaacaacacg aattaatcaa
     2821 catcggtaaa gctggacgct ctcgttggat gcgtaaacgc ccaactgtac gtggtagcgt
     2881 aatgaaccct aatgatcacc cacacggtgg tggtgaaggt aaagctccta tcggacgtaa
     2941 agcaccagtt tctccttggg gtcaaccagc tcttggttac aaaactcgta acaaaaaagc
     3001 taaatcagac aaacttattg ttcgtcgtcg caaaaataaa taattacttt gaccatgtgt
     3061 cgcacatttt gagaggaggt tcaccatggg tcgtagttta aagaaaggac cttttgtcga
     3121 tgagcattta atgaaaaaag ttgaagctca agcaggggtt gaaaagaaaa aagttatcaa
     3181 aacttggtca cgccgttcaa cagttttccc aagttttgtt ggatatacca tcgcagttta
     3241 tgatggacgt aaacatgtac cagtttacat ccaagaagac atggtaggac acaaattagg
     3301 tgaatttgca cctacaagaa cttatcgtgg acatgctgct gacgataaga aaacgaaacg
     3361 ctaatttgag gggaggataa atccaaatgg cagaacaaat cacatcagct aaagcaactg
     3421 caaaaacagt tcgcacttca cctcgaaaag cccgtttagt aattgacctt atcagaggta
     3481 aaagtgtcgc agatgcaatt tcaatcttga aattcacacc aaacaaatct gctggaatca
     3541 ttgaaaaagt attgatgtca gcagttgcga atgcagaaaa taactttgac ttagatgttg
     3601 aaaacttggt agtaagcgaa gcttttgtta acgaaggacc tacaatgaaa cgtttccgtc
     3661 ctcgtgcaaa aggatcagct tctccaatca acaaacgtac aagtcatatc acggtagtcg
     3721 tatcagaaaa ataaggaggg ataatcagtg ggtcaaaaag tacatccaat tggaatgcgt
     3781 gtaggcatca tccgcgactg ggatgctaaa tggtatgctg aaaaagagta tgctgagttc
     3841 ttacacgaag atttaagaat ccgtaaattt atttcaacta aacttgctga tgctgctgta
     3901 tcaacagttg aaatcgaacg cgcaacaggt cgcgtaaaca tttcaattca cacagctaaa
     3961 ccaggtatgg ttattggtaa aggcggttct gaagtcgaaa gcctaagaaa agaattaaac
     4021 aaattaactg gtaaaagaat ccatatcaat atcgtggaaa tcaaaaaacc agatctagat
     4081 gcaaaattag taggtgaagg aatcgcacgt caattagaaa accgtgttgc tttccgtcgc
     4141 gctcaaaaac aagccatcca acgctcaatg cgtgctggcg ctcaagggat caaaactcaa
     4201 gtatctggtc gtctaaacgg agcagatatc gctcgttcag aaggatactc agaaggaact
     4261 gttcctcttc atactttacg tgcggacatt gattacgcat gggaagaagc agatacaaca
     4321 tacggaaaac taggagttaa agtgtggatc tatcgtggag aaattcttcc aactaaaaaa
     4381 aacactgaga aaggagggaa ataatcatgt tagtacctaa acgtgtaaaa caccgtcgtg
     4441 aattccgcgg aaaaatgcgc ggggaagcta aaggcggaaa agaagtagca ttcggtgaat
     4501 acggtttgca agctgttgat tcacattgga tcacaaaccg ccaaatcgaa gctgctcgta
     4561 tcgcaatgac tcgttacatg aaacgtggtg ggaaagtatg gattaaaatt ttccctcaca
     4621 aatcttatac tgccaaagca attggggtac gtatgggttc tggtaaaggg gcacctgaag
     4681 gatgggttgc accagtaaaa cgtggtaaaa tcatgtttga aatcgcaggc gttcctgaag
     4741 aagtagctcg tgaagcgtta cgtctagctt ctcacaaatt accaatgaaa actaagatcg
     4801 taaaacgtga ggaaatgggt ggtgaatcga atgaaggtta aagaaatcag agaattaacc
     4861 actgccgaaa tgcttgatca agaaaaacaa ttaaaagaag aattgtttaa tcttagattc
     4921 caattagcaa caggtcaatt agaaaacact gcacgtatta aagaagtacg taaatcgatt
     4981 gcacgcatca aaactgtgtt gcgtgaacaa gctaagtaat tatggaagga ggccattaag
     5041 cgtatgactg aaggaagaaa tcaacgcaaa gtttatcaag gtcgcgtggt ttcagacaaa
     5101 atggataaaa caattaccgt tgctgtcgaa acaaagaaaa accaccctat ctatggcaaa
     5161 cgcatgaact attctaagaa atacaaagtg catgatgaaa acaacacagc aaaagttggc
     5221 gacatcgtga gaattatgga aactcgtcca ttatcagcta caaaacgttt ccgtttgttg
     5281 gaagtagtcg aagaagcagt tattatctaa taacacgaga ttttcctata tagattgaat
     5341 gcaaaatctg aaaggaggat acacaacgtg atccaagcag aaagtcgttt aaaagtcgct
     5401 gataactcag gcgcacgtga aattttgacg atcaaagtcc ttggtggatc tggtcgtaaa
     5461 actgctaaca tcggtgatgt gatcgttgct acggttaaac aagcaacgcc aggtggggtt
     5521 gtcaaaaaag gtgacgtcgt taaagccgtt atcgttcgaa caaaatcagg agctcgtcgt
     5581 acagacggtt catatattaa atttgatgaa aatgctgcag tgattattcg tgatgataaa
     5641 agccctcgtg gaacacgtat ctttgggcca gttgcacgtg aactacgtga aaacaacttc
     5701 atgaagatcg tttcactagc accagaagtt ttataatctt gagacactta tcaaaggagg
     5761 tgcgaaacag ttatgtttgt taaaaaaggc gataaagtta aagttatcac tggaaaagac
     5821 aaaaacaaag aaggcgttgt actagcagcg ttcccgaaaa aagataaagt tattgtcgaa
     5881 ggtgtaaatg tcgttaaaaa acaccaaaaa ccttctcaag ctgctcctca aggtggaatt
     5941 gttgagatgg aagcgccaat tcatgtttct aacgtgatgg tggttgactc tactggtgta
     6001 gctggccgag ttggctacaa agaagtagac ggcaaaaaag tccgtgtttc taaaaaaacc
     6061 ggtgaagttt tagataaata aaagtttaag gaaggagggt cttactgaat gaaccgccta
     6121 aaagaaaaat atcttaaaga agtaactcca tcattgatgg aaaaatttaa ctatagctct
     6181 gttatgcaaa cacctaaagt tgaaaaaatc gtcatcaaca tgggtgttgg tgatgcggta
     6241 tcaaacgcta aaaacttaga taaagcagtt gaagaattaa ctttgatcac tggtcaaaaa
     6301 ccaatgatta caaaagctaa aaaatcaatc gctggattcc gtttacgtga aggaatgcca
     6361 attggtgcaa aagttacatt gcgcggagaa agaatgtacg aattcttaga caaattggtt
     6421 tctgtttcac taccacgtgt acgtgacttc catggtgtaa gtaaaaaagc ctttgacggt
     6481 cgtggaaact atactttagg tattaaagaa caattgatct tcccagaagt agattatgat
     6541 ttagtagata aagtacgtgg tatggacatc gttattgtaa caacagcaaa ctctgatgaa
     6601 gaatctcgtg agttgttgac acaattaggc atgccattcc aaaaataatt aaaggaggcg
     6661 aactacgtgg ctaaaaaatc aatgattgct aaaaacaaac gtcctgcaaa attttcaaca
     6721 caagcttata ctcgttgcga acgttgcgga cgtccacatt cagtttatcg taagttccat
     6781 ctttgccgta tttgcttccg cgaacttgcc tataaaggtc aaattcccgg cgtgaagaaa
     6841 gctagctggt aaaaagtaaa ttcgcataag aaggaggtaa aagatcaatg gtcatgacag
     6901 atccaattgc agattttcta actcgtatcc gtaacgcaaa catggttaaa catgagtctt
     6961 tagaagtacc tgcatcaaaa attaaacgtg acatcgctga aatcttgaaa cgtgaaggtt
     7021 tcgttcgtga tgttgaatac atcgaagatg acaaacaagg cgtgatccgt gttttcctaa
     7081 aatttggtaa aaacggcgaa cgtgttatca caaacttaaa acgtatctct aaaccaggtt
     7141 tgcgtgctta tgtcaaagct gacgaagtac caaaagtatt gaacggttta ggtatcgcaa
     7201 tcatttcgac ttctgaaggt gttgtcactg ataaagaagc tcgtgaaaaa aatatcggcg
     7261 gcgaagttat cgcttacgta tggtaatcaa gtagaatcta caaggaggtg tctttaagtg
     7321 agccgtatcg gaaataaagt cgttgttatc cctgaaggag taacagttac tcaagacgga
     7381 aacaacgtta cagttaaagg accaaaaggt gaattgactc gtactttttc agcagatatc
     7441 aaaatgaata tcgaaggaaa cgaagtaact ttcactcgtc caaacgacag taaagaaatg
     7501 aaaacaattc atggaacaac tcgtgcgaac ttcaacaaca tggttgtagg tgtcagcgaa
     7561 ggtttccaaa aagcgttaga actaatcggg gttgggtacc gtgcacaatt acaaggatca
     7621 aaacttgtat tgaacgttgg ttactcacat ccagtagaaa tcacaccacc agctggagta
     7681 actgttgaag taccagctaa cacacaagta attgttaaag gtgcgaacaa agaagaagtt
     7741 ggcgaattag ctgcaaacat tcgtggaact cgtcctccag aaccttataa aggtaaaggt
     7801 attcgttatg ttggcgaata tgtacgccgt aaagaaggta aaactggtaa ataatcgttt
     7861 agaaaaattg catagaagcc agcagcagga aaaaggcatt tggctgaagt ttaccttcaa
     7921 aaaaatacat ttttacttgt gccgcagctt ctatttttcg aaacgtattt actgcttgaa
     7981 atagtagtac aataaaaata aagaggtgac aattgtgatt acaaaaccag ataagaacaa
     8041 aacacgtcaa aagagacatc gtcgtgtacg taacaatatc tctggtactg ctgagcgccc
     8101 acgcttgaac gtttttcgtt ctaacaaaaa catctacgct caaattattg atgacgtagc
     8161 gggtgtaacg ctagcaagtg cctctacctt ggataaagaa atttcaggtg gaacaaaaac
     8221 agaagcagca caagctgtcg gtaaactagt tgctgaacgt gcagctgaaa aaggcattaa
     8281 agtagtagtc tttgaccgtg gtggatacct ttaccatggc cgtgtgcaag ctttagctga
     8341 agctgctcgc gaaaatggac tagaatttta gaagaaggag gaataccatt catggtttat
     8401 atcgatccaa aacatttgga attagaagac cgcgttgttg caattaaccg tgtaacaaaa
     8461 gttgttaaag gtggacgtcg tctacgtttt gctgctttag ttgttgtcgg tgacaaaaac
     8521 ggacacgtag ggtttggtac aggtaaagct caagaagttc ctgaagcaat ccgtaaagca
     8581 attgaagatg cgaagaaaaa cttagttgaa gtacctatgg ttggttcaac aatcccacac
     8641 gaagtaatcg gtgcttttag tggtggtaga atcctaatga aacctgctgt agaaggttct
     8701 ggggttgctg ctggtggacc agttcgtgcc gtattagaat tagctggggt agcagatatc
     8761 acttctaaat ctttaggctc aaatacacca atcaacgttg ttcgcgcaac agttgaaggt
     8821 ttgaaacaat tgaaacgtgc agaagaagtt gcagaacttc gcggcaaatc agttgaagaa
     8881 ttaatcggat aaggaggaca acaataatgg ctgaattaaa agttacttta aaacgcagta
     8941 ttatcggacg tcctcaaaac caacgcgata cagttaaagc gttaggtctt acaaagatta
     9001 acagttcagt ggttaagcct tctaatgaag caattaaagg catgatcaat actgtttctc
     9061 acctagtgga cgttgaagaa atttaattta gaaaaatcat aactagaaca ttaaggaggt
     9121 gccaaaccta tgaaacttca tgaattaaaa cctgctgaag gttcacgcca agtacgtaac
     9181 cgtgttggtc gtggtacttc atctggtaac ggaaaaactg ccggacgcgg acaaaaagga
     9241 caaaaagctc gttcaggcgg cggtgtgcgt ttaggatttg aagggggaca aacaccattg
     9301 ttccgtcgtt taccaaaacg aggattcaca aacgtgaacc gtaaagacta tgcagtcatt
     9361 aatcttgatg tattgaaccg ctttgaagac ggagctgaag taactcctgt tgctttagtt
     9421 gaagctggaa tcgtgaaaaa cgaaaaagct ggaatcaaag tattagctaa tggggaacta
     9481 aacaagaaat taactgtgaa agcagcaaaa ttctctaaag cagctcaaga agcaattgaa
     9541 gcggctggtg gatcaatcga ggtgatctaa tgtttagact attaaaagat gcttttaaag
     9601 taaaagacat tagatcgaaa atcctattta ctgtatttgt gttgtttgta tttcgcctag
     9661 gtgcacatat tactgtacca ggcgtaaatg ctgcttcatt gcaaaacctt tcttctttgc
     9721 catttttcaa catgttgaac ttggtaagtg gtagtgcgat gcaaaacttt tccattttct
     9781 caatgggggt ttcaccatac attactgctt ctatcgtcat tcagcttctt caaatggaca
     9841 tcgtgcctcg atttgttgaa tggtcgaaac aaggggaagt tggtcgtaaa aaactgaatc
     9901 aagcgactcg atatctgaca ttagtattgg catttatcca atctgtcggt atcactgctg
     9961 gattcaatca atacgctcaa ttaggtttcg tgaataatcc taacgtagca acttacgtaa
    10021 cgatcggttt gattctaaca gccggtacga tgtttgttac ttggctagga gaacagatca
    10081 cagaaaaagg tatcggaaat ggcgtatcaa tgatcatttt tgcaggtatc atttctagat
    10141 tgcctgaaag tatcagagaa atttatgaag attactttat aaatattgat ccttcagaca
    10201 tatggaaatc tgctattttt gtggccattt tactagtagc ggtcttgttg atcgtgacat
    10261 tcgtaacatt tttccaacaa gctgaacgca agatcccgat ccaatatacg aaacgcgtag
    10321 ctggcgcgcc tacaagcagc tatctgccgt tgaaagtaaa tgcagctgga gttattccag
    10381 ttatctttgc tagttcgttt attgctacgc caaatgctgt tttacaagca ttgagcggta
    10441 gattcggttc tgaaaactgg tacaaagtga tgatggagat ctttaactat aatacagcac
    10501 ctggtgctac gatttatacg attctgatcg ttgccttcac tttcttctac gcctttgttc
    10561 aagtaaaccc tgagaaatta gcggaaaact tgcaaaagca aggaagttat ataccaagcg
    10621 tacgccctgg taaggggact gaagagtatg tctcaagatt actgatgcgt ttaagtacag
    10681 ttggtgcagt cttccttggt ttagtggcat tgcttccaat cattgctcaa atggtttggg
    10741 atcttccaca atcaatcgga ttaggcggta caagcttact gatcgttatc ggtgtagctt
    10801 tagaaactgc gaaacagtta gaaggcttaa tgctgaaacg taaatatgtt ggattcattg
    10861 agtaagaaag cgtgttgagg tttcccctca acacacgttc tcacacattt attaggaggg
    10921 aaaacaatga acctcatttt aatggggctg ccaggcgcag gtaaaggaac acaagctgaa
    10981 aaaatcattg atgcttatgg tattccgcac atctcaacag gagatatgtt ccgcgcagcg
    11041 atgcaaaacg aaacagctct tggcctggaa gcaaagtctt atatggataa aggtgcatta
    11101 gttcctgatg aagtaacaaa tggaatcgtg aaagagcgac tagctgaacc agatacagag
    11161 aaaggcttct tattagatgg ctttccacgt acgctagatc aagcaaaagc tctggacgca
    11221 atgctaaaag atttgaataa aaaaattgat gctgtcatcg atatccatgt tggtgaagaa
    11281 atcttggtcg aacgtctagc cggccgattt atctgcagca attgtggagc aacttaccat
    11341 aaaattttca accctacaaa agttgaagac acatgtgatc gttgcggtgg gcatgaattc
    11401 tatcaaagag aagatgataa acctgagacg gttaaaaatc gtctggctat caacatcaaa
    11461 aatagtgaac caatcttggc ttattataaa gaacaaggtt tgctaaacac tattgatggt
    11521 gctcgtgaaa tcgatgctgt atttgcagat gtacaaaaaa tcattgaaaa atagcacgat
    11581 tgcccgtagc cgacttgcat tatgcagtta ctcttgtcaa gttcaataaa ttatgataga
    11641 atatgtcagt ccgacttcta gagaatcctc tagatgatcc attttgagaa ttttgaggtg
    11701 ggaactgcag tttccgccat tttatcgtgt gaaaatgcga aacaagtaca aggaggtact
    11761 gtgcgtggca aaagaagata tgattgaagt cgaaggtaca gtcgtcgaaa ctttgccgaa
    11821 tgcaatgttt aaagttgaac tagaaaacgg acaccaagtt cttgctactg tttcaggtaa
    11881 aattcgtatg cattacatcc gtatcttacc tggtgacaaa gtaacggttg aattgtctcc
    11941 atacgatctt aaccgtggcc gtattactta tcgctttaaa taattgtact ccgtaaaact
    12001 acaggaggta ttatcatgaa agtaagacca tcagtaaaac caatgtgcga acattgtaaa
    12061 gtaattcgtc gtaaaggacg cgttatggtg atttgcccag caaatccaaa acataaacaa
    12121 cgtcaaggat aattggaggt gctataaata tggctcgtat tgcaggagta gatattcctc
    12181 gtgataaacg tgtagtagtt tcacttactt atatctatgg tattggtaac actactgcta
    12241 aaaagatctt agctgatgct ggtgtatctg aagatgttcg cgttcgtgaa ttaacgaatg
    12301 aacaaacaga tgctatccgt gcagaagtag ataaattaaa agttgaaggg gatcttcgtc
    12361 gtgaagtgaa cttgaacatc aaacgtttga tggaaatcgg ttcttaccgt ggaatccgtc
    12421 atcgccgtgg attgcctgtt cgtggacaaa acacgaaaaa caatgcacgt actcgtaaag
    12481 gcccagctcg cgctatcgct ggcaagaaaa aataattctt aagtgaagga ggttaaaact
    12541 tcatggcagc aaaaaaagtg aatcgtaaac gccgtgtgaa gaagaatata gaagcaggta
    12601 ttgcacatat ccattctaca ttcaataaca ctatcatcat gatcactgat actcacggaa
    12661 atgcattagc gtggtcatca gctggttcat taggtttcaa aggaagcaaa aaatcaactc
    12721 cttttgccgc tcaaatggca gcagaaactg ctacaaaagc agcaatggaa cacggattaa
    12781 agactgttga agtaacagtt aaaggacctg gttctggacg tgaagcagca attcgttcat
    12841 tacaagctac aggtttagaa gtgactgcaa ttcgtgacgt gactccagtt cctcataatg
    12901 gtgcccgccc tccaaaacgc cgtcgtgttt aatgagtgcc gctcattttg agttttatca
    12961 gtaacgtcat tgaacaagac acttttcgtt ttgaaagggg taaagataag aatgattgag
    13021 ttcgaaaaac caagaatcgc aaaaattgat gaagaaaaag attatggcaa gttcatcgtt
    13081 gaacctcttg aaagagggta tgggactact ttagggaatt ccctacgtcg tattttatta
    13141 tcttctttgc caggtgctgc catcactaat attcaaatcg atggtgtact gcatgaattc
    13201 tctaccatca aaggtgttag agaagacgtc actcaaatca tcttgaacat taaaggctta
    13261 gcgctgaaaa tgtatggcca agaagaaaaa acccttgaaa tcgatattac cggacctgct
    13321 acagtaactg ctggcgatat tatcgttgat agtgatgtag aaattcttaa caaagatatg
    13381 tacatctgta gtgtctctga aggagctacg ttccatgctc gcttaacagt gaaacctgga
    13441 cgtggttatg ttcaagcaga tgaaaataaa aaagaagata tgccaattgg cgttcttcca
    13501 gtcgattcaa tctacacacc tgttcgtcgt gtgaactatc aagttgagaa cacacgtgtt
    13561 ggacaccgtg aagattttga taaattgacg atggagattt ggacagatgg ttcaattgaa
    13621 ccgttggaag caatgagttt gtctgcgaaa atcatgactg aacatttgga tatttttgtg
    13681 aacttaactg atgaagcaaa aaatgctgaa atcatggtcg aaaaagaaga aacacaaaaa
    13741 gaaaaaatgt tggaaatgac gatcgaagag ttagacttgt ctgttcgctc ttacaattgt
    13801 ttgaaacgtg caggaatcaa tactgtacaa gaacttacaa ataaatctga gcctgaaatg
    13861 atcaaagtcc gtaacttagg acgtaaatca ttagaagaag ttaaagcaaa attgcacgac
    13921 ttaggtttag gtttacgtaa agaagattaa aaccttttac gaaggaggga aaccaacgtg
    13981 agttatcgta aactaggacg cacatctagc caacgtaaag cgatgttgcg tgatttaaca
    14041 actgatttat taatcaacga acgtattgtg actactgaag ctcgtgcgaa agaagttcgc
    14101 tcaactgcag aaaaaatgat cactttaggt aaacgcggag atttgcatgc acgtcgtcaa
    14161 gctgcggctt tcgtacgtaa tgaagttgcc agcgtgcgtg aagaaaatga ggacatcgtc
    14221 attgaatcag ctttacaaaa actgttcaac gatattgcac ctcgttacgc agaacgtcaa
    14281 ggcggataca cacgcatttt gaagacagaa ccaagacgcg gtgatggtgc accaatggtt
    14341 gtcttagaac ttgtctaaaa tcacactaat aacatcactt tatagatgat tcttttagag
    14401 tgttatgatg ttggaagata tttttccgag tctagctcag cgctgctcct caagcgaata
    14461 tcgcttgggg agtaagcact catcataaag tgttttttta taccttcaat tacctgtcat
    14521 gacagatatg tttgaaggca taaaaaaaca ttttaagcga gaaataattg aaaattttgt
    14581 ctttttttga tagtgttagt aggaacttta ggatgaagaa ggagtaatca tggagccaat
    14641 tattgaatta gaaaagataa attataaata ccagccagat gatcttcgcc ccgcattgaa
    14701 agatgtctcc tttacaattg ataaaggtga gtggatcgct attattggac acaatggttc
    14761 aggaaaatcg acacttgcca aaacgatcaa tggattgctt ctgccagaat cagggatcgt
    14821 gaaagtggga aatcaaatat tggatgaaga aaatatttgg acgatccgac agatggttgg
    14881 aatgattttt caaaatccag acaatcagtt tgttggttcg acagtagaag atgacgttgc
    14941 ttttggtctt gaaaatcaag ggattcccag agaagaaatg ctagtgcgtg tgaaagatgc
    15001 acttgagaaa gttagaatgg ctgagtttgc ttcacgcgag cctgctcgtt tatcaggagg
    15061 gcaaaaacaa cgtgttgcca ttgccggcgt ggttgcctta cgacctgata tcattatttt
    15121 agatgaagca accagtatgc tagatccaga aggtcgtgaa gaagtgatct ctacgatcaa
    15181 gaagatcaaa gaagaaagtc aattgaccgt tatatctatc actcatgata ttgatgaagc
    15241 agctaatgcc aatcggatac tagtgatgag acaaggcgaa cttgtccgtg aaggtacacc
    15301 aaaagaaatt ttttctgctg gtcctgaact gatcgactta ggtctagatc taccatttcc
    15361 tgaaaaactg aagagcgcac tgaaagaacg tggggttgat gtgcccagtg aatatatgac
    15421 agaagaaagg atggtggatt ggttatggac atccgttttg aacaagtaga cttcacttat
    15481 cagccgaata caccatttga acaaagagcc ttatttgaca tcaatatgac gatcaaagaa
    15541 aacagttata ctgcattagt agggcatacc ggaagcggga aatcaacctt acttcagcat
    15601 ttgaatgcgc ttgttaagcc aacaagcggt acagtccata ttggagaacg agatattcag
    15661 ccggatacgg ataataagaa tttaaagccc atccgaaaaa aagttggcat cgtctttcag
    15721 tttccagaag cacagctatt cgaagaaacg gtagcaaaag acattgcttt cggtcctaaa
    15781 aactttggtg tcagcgaaga agaagcacta gtcctagcaa aagaaacatt agaacaagtt
    15841 gggctggatg aaagctattt ggaacgttcg ccatttgaac tttcaggagg gcaaatgcgt
    15901 agagtagcaa tcgctggtgt gcttgccatg aggccggaag tacttgtatt ggatgaacca
    15961 acggcaggac ttgatcccca gggcagaaaa gaaatgatgg agatgttttg gcgtcttcat
    16021 aaggaacagc agatcactat tgtattagtt acgcatttaa tggatgatgt agccaatttt
    16081 gcagattatg tctatgtgtt ggaaaaggga cgaatcgtta atagcgggga gccgcaagag
    16141 gtctttcaaa acattgaatg gctaaaagaa aaacaactag gcgtacctac tgccaccgag
    16201 tttgcagaag aattaatggc taaagggatg aactttgcta ccttgccttt gacagctgaa
    16261 gaattagcag acgctatcgt ccattatgct ggaggaaatg cccatgatga ataaattgat
    16321 atttggtcgt tatatgcctg gagattcctt gatccatcga ttggatcccc gagctaaatt
    16381 attagccagt ttttatttta tcggaatcat ttttttagca aataattggg aaacgtacct
    16441 tttgttggca tttttcacat tactttctgt cttcttgtca aaagtagatt tgaaattttt
    16501 tatccgaggc attcgcccat tgatctggct aatcctcttc actgtagctt tgcaggtctt
    16561 gtttacaagt ggcggagaaa cttattggag ttggggtgtt ttccatatca ctgaatttgg
    16621 tgtgatgaac ggcctcttta ttttctgtcg attcgtgttg atcattttta tgtcgactct
    16681 actcacgctt actacaccgc ctttggaatt atcggatgcg attgagtact tgcttcgtcc
    16741 attgaaagcc gtacggttcc cagtccacga aatttcattg atgctgtcga ttgctcttcg
    16801 ttttgtgcct acattgatgg acgaaacaga aaagatcatg aacgctcagc gcgctcgcgg
    16861 tgttgatttt ggtgaaggaa acctagttca gaaaatgaaa gcagtcattc ctttgctgat
    16921 tcctttattt gtcagcagct tcaaccgtgc ggaagatctt gcgactgcta tggaagcaag
    16981 aggctacaaa ggtggggaag gaagaacgaa atatcgtgta ttgcattggc ataatagaga
    17041 cacgatggtt atcattgctt ttgtattatt aactgtgcta ctgatctttt taagaggata
    17101 aacgttcagt gggccgctat ctattctttt cttgctgatc tgtttgcaag aaaggatgca
    17161 agcagtgtat gacaagaaat attagggtct gtggcagact aaggtcacag gcctctttct
    17221 tttatctgaa aagaaagaac gaaaaaattt tatagaaaaa tcattattcc agataacctt
    17281 ttaggaacaa aggagagaaa aacatggtac gttacaaagc aatcattgcg tacgacggaa
    17341 caaattttaa tggattccaa aaacagccaa atgggcgtac tgttcaagaa gaagtagaaa
    17401 aaacattaca aaaaatggca aatggaaaag aaatcacggt ctttggttcg ggaaggacag
    17461 atgccggagt acatgcgatc gggcaagtaa tccattttga ttatccagag gagcgtccgt
    17521 tagaacgaat gcgtttcgcg ctagataccc agtcaccaga ggatattgct gtaagacaag
    17581 tagaaattgt ttcagaagac ttccacgcaa gatatttggt caaagaaaag acgtatcaat
    17641 ttcgagtgga tatagggaaa ccacgcagtc cttttcgacg ccattatgca agttattttc
    17701 cttacccact tgatttggaa aaaattcagc gggcgcttcc tgatttatta gggactcacg
    17761 atttcacctc tttttgtgca tcaggaagct cgatagagga taaaatacgt acgatctacg
    17821 aggctaagat ggaggtaaat gaaacaaaag acgaattgtt gtttacattt aggggaaatg
    17881 gcttcttgta taagatgata cggatcttag taggaacgct tttgaaaatt ggcaatggcc
    17941 gattgcctga agatagtatc ccagatatta ttgcgaaaaa agatcgtaat gcagcaggac
    18001 ctacagcaca ccctgaagga ctttatttgt atgaagtgaa atatgaataa gaggttatga
    18061 tagaagtggt cagcttcaag aaataagaag gtatttacga aaattacttc tcaaaatttt
    18121 gcaaaatttc ggcttatttt cgaagaagct acttctggaa caccgtttaa gaaagaggtc
    18181 gtgagcctgt catttaactc tgagtcacaa agagcaattt caaaaaacag cttctcatct
    18241 ttgatgaata tcgtgacttg tggacgaggc gttgataagt gaatcatctt tttgttacct
    18301 attttttctg taaccaaaaa acgatggaac gttgttttga ttgcccttgg tgcggacagt
    18361 ctgaacaggt tccatcgttt ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt
    18421 gttcttctat tgctggatca atcgtgccat aaaaggggcg attgcggtca aggtaccaga
    18481 cataaagaat aaacaatgca atacatagga caaaaaggat tgcacctatc gtaaatcctt
    18541 caggcaagta actgaaagtg acagtatgtt tacctgctgg aacttttatc atcaagaatg
    18601 cgtctttgaa attgctgacc ttgactggtt tcccatcaat tttagctttc catcctttgt
    18661 cataaggaat agttgtcacc aacatggaat cttcagcggt atttacagtc ccagaagctt
    18721 ttctgccagt ggcttccatt tcgacacctt tttctttgat ctgattcatt gcggcttgat
    18781 aggctacaac atctagacca acgactttag gctccatgaa acttatttct ttcgtcccat
    18841 aaaaacttgc agtaaatgtc actgttgtct cttgaggata atagccaaga tcatagtatt
    18901 gaccagaaat gttgatttgc gtttttcgcg atgtaccatt gacagtgatc gtcgcactag
    18961 aactttctaa ttgcgcaaaa ttggttggga acaaacttaa gtaagcttgt gtatttgcag
    19021 gcacatggac ttcccaagtg agctcttttg gctggttatc tgctgtttct gagtaagtga
    19081 cgccagtcgt tgtctttgtg atcgtcgtat tcaactgatt cttcaaagta ggtgtataga
    19141 atgtaaaata ctgttcattt agaccagaca atgtattgat caagtttgtc tgactggtca
    19201 aattatctgt cactggctgc tcaacatcat taacggacaa cggtgcagta aatgctagtg
    19261 gcaatgcatt gacattctga tacagtgtat agtcgccgct ttgaccagct tggcggaagc
    19321 catatttact gaacgtgctt tcgtttttag aaatgttata tttgattcct gtaaacccat
    19381 ccatcagcaa agtattattg ttataacgga tattcaaatt tgtccctctt gaacggaaac
    19441 ctaatttatc caggtaagag gaagaattac gatttcttat agaagaaaac aaactgatac
    19501 cactgtaacc atagttgatc gaatcgtttg cagatactgg atccagattt tccaagcggt
    19561 aaaacgagtc ggaatctttt tttgtttcat ttacaagagc tttcaagtca ggataaggat
    19621 cagtatataa actgcgggaa gcataattcc aatcatcaag aatgccatgg atcatactgt
    19681 tcgtattgac cagtgcttca gcagacatga tcaataataa caatatactc agatgattga
    19741 atgaaagttt tttatgctga taaaatccca cagcaaaagc ataaatccct aagaaaacca
    19801 ctgtcaatac aaaggaagtc atcgtcacat aggtgtagct tccttcaggt ttgatgcccc
    19861 atgccaccgc aaagagagca gctacgacca aaatgattcc taacaacagc ccaccatcgt
    19921 cttgttctat cttttcccat ccttttcctg caagcaggag cactaagaaa gagaacagat
    19981 aggcataacg gaataaaaac atattcggtg catgcatacc atgccagaac aaattcaatg
    20041 gaacaagata aaaacttgcg ataagtatgg cgaaaagact gccgtacaaa aatttatttt
    20101 tcaacggtac tttccgactg gcaaaataaa acagacagag gactaatggt agcagacctg
    20161 cgtaaacgaa cggaatcgat ccgtattttg tcgtgtcata aacaccaatc atatttttca
    20221 tgattagatc cagataagaa gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct
    20281 cgccatttga ccgaagatcc agcactgctg gcaatacaat gatcattgaa gcgccgcctg
    20341 ccagtaaaga agtgatacca taaggaacaa tcgttttttt atattctgac cagtttgtca
    20401 atagacgggc gataaaatat aagaaagaaa atacgccaat cataaaaccc atataaaaac
    20461 tggataaaaa caagagtaaa taactgataa ataaaagttt cggccgttta agatccataa
    20521 cacgatgaat ccccaaaatc actaatggaa gataaacaaa tgcatccagc cacatgatga
    20581 tctccgaatg tgcagtgata aatgagatca atgcgtaact gacgctaagt gcaacatgcc
    20641 cccagcgagg aatcttgaac gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga
    20701 ccttaagcaa agtcagaaca tacagtgcat ctggcatcat ctggtttgga aaaaagaaca
    20761 ccagtggcgt gaagatcccg cctagatagt aagaaattaa agataaataa ttcaatccta
    20821 gagaagcatt ccatgtataa aaaatacttt gctttccaag aagaacattt cggaagctgg
    20881 catgaaaatt agaaaactgt gaaaaggcat cacttgccaa aatacttctg ctgcttccag
    20941 gatagattcc gatacttaga taaacaagtg ctaaaatcaa aaacggaatc aggaaactag
    21001 ctgctgcgta gcgtccgttt tctctaaaga atgactttaa attttttttc atatttattt
    21061 tccaccaaat ttctatgaag ttgtattcag tttatcatat ccttgttttt ctctgcttaa
    21121 aaagagtcta gttttcacaa aaaaataaaa tttagaataa ataacttcat aatttgttcg
    21181 tataacaaaa ataaacgcaa aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt
    21241 tattaaataa aaaaccgttc actatctgaa cggtccaagt atcattcaat taaacgcgtt
    21301 caacttttcc tgatttcaaa gcacgagttg acacccaaac ttttttaggt tttccgtcga
    21361 ccataacgcg aactttttgt aagttaggtt taacagtacg ttttgttgag ttcatagcgt
    21421 gtgaacggtt gtttccactt tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg
    21481 taatttcctc ctttgccttg atttggagca atagaataat tcagctcata ccagactaac
    21541 atatcatata gaatgggaat ttgcaagtac attttcatag atacaattga caattgagaa
    21601 gaataattgt aaattaaaca aggttatacc tgaaattttg caaggttttt gagtactttg
    21661 ggtaactgcc ttttatttca agttgcgcta tgataaaata tgatagaaga aaaatgggag
    21721 ttttttaccc gttaaggagg ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc
    21781 attgaaatta ccaatgatgt aattgcaaca gttgttggtg gcgccgcgac agatgtgttc
    21841 ggtgttgtag gaatggccag caaaaatcaa attaaagata atattactga gattttgcgt
    21901 aaagaaaatt actcaagagg agtagttgtc cgccaagaag ataatggtat tgctgtagat
    21961 gtttatacga ttatcagcta tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa
    22021 aaagtgaaat acaatctaga ggcattatta ggcgtaactg ccaattcagt taatgtcttt
    22081 gtacaaggtg ttcgtgtact gccagactag gcaggagact ggctggtaac tcagcagtcg
    22141 atctgaagga ggattatcta ggtgagtgta acagaaataa gtgcaagcca gttccaggaa
    22201 atggtccagg caggtgcgaa tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat
    22261 gtattccctg tgccagatgg cgatacggga acaaatatga atctatctat gactagtgga
    22321 gctaaggcag tagtagattc aacctcagaa aaagtaggag aattagcagc aatgctttca
    22381 aaaggattgc tgatgggtgc gcgcggaaat tccggcgtta ttttgtctca attgtttcgt
    22441 ggattttcta agcaaattcc agatgttgtc tcattaaatg cttctgatct tgctgcagcc
    22501 ttcactcatg gagttgaaac tgcgtataaa gcagtaatga aaccagtaga aggaacgatt
    22561 ttgacagtag ctagagaagc agcgaaagct ggagaaaaga aagcaaaaag tactgatgat
    22621 gtcgttgaag taatgacagc tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca
    22681 gacttgcttc cagtcctaaa agaagtcggt gtcgtagaca gtggagggca aggactgctg
    22741 tttgtttatg agggcttttt aagtgcattg aatggagaat tccaagcgga tgaaacatat
    22801 gaaccttctc cagcagaaat ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa
    22861 ggtcaaatgg cgacagaaga tatccatttt ggttactgta cagaaatcat ggtaaaaatc
    22921 ggagaaggac ctacagtcga tagtacattc gattacgaag aattccgtaa ctatttagat
    22981 ggtataggag attctttact tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat
    23041 acagaaaacc caggagaagt cttgaattat ggacaaaaat tcggttcatt agtcaaaatc
    23101 aaagtcgaca acatgcgctt gcagcatgag acgattttgg aacacgatga agaagtgaac
    23161 gagtttgcga aaaaagaaat accacgtatc ccgtatggta tcgtagcgat cgctgctggt
    23221 aaaggcgtcc aagagctgtt tgaaagttta ggcgctaatt atgttatcag tggtggacaa
    23281 acaatgaatc caagtacgga agacattgtt aaagcgattc aagaagtaaa cgcagataaa
    23341 gtgattgtct tgccaaacaa taagaacatc ttcatggcag ctgatcaagc agcagaagta
    23401 gcagatatcc cagtagcagt tgttccttca agaacgattt cccaaggatt gacagctatg
    23461 ctttcattca atgatcaagc ttctttagaa gaaaacaaag aaacgatgac agaaatgttg
    23521 tctagcgttg tgagcggtca agtcactcac gcgatcagag atacctcaat tgacggtgta
    23581 gagatcaaag aaggagactt tttgggcatg atcgatggaa aaatcctgat ctctaaccca
    23641 gatatcacag caacagcgtt aagtacacta gaacaaatga tcaatgagga cacagagatc
    23701 gtaacgatct tggcaggtga tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa
    23761 ctaacagaaa aacatcctga tttggaaatc gagatccacc aaggagatca gcctgtctat
    23821 ccttatctat tttctgctga ataatttctg tgtcagaata tctttctaac acagtattca
    23881 ttcataaaag gccttcggtt agtgatcagg tatgatcgct gaccaagtcc tttttttgtt
    23941 aaaggaggga ggaaaaattt atgcgttctt tagatgatcc aatcactatg ctggcaggag
    24001 tcggagaaaa aagagcagct agtcttgcca gcttgggcat ccaaacgatt gaagacttac
    24061 tgacttatta tccttttcgc tacgaagata ttcaggaaag aaatctaaac gagatccagg
    24121 atcaagaaaa ggttactttg aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg
    24181 gttataaaaa aagccgattg caatttcgta tgatgcaaga acatgatgtg ttcaacgttt
    24241 ctttttttaa tcaaccttat ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat
    24301 acggtaaatg ggatgcaaag cgtaaagcct tgaacgggat gaagatttta ggttctcaaa
    24361 caatggatga cttttcgccg atatatcacg tcaacaaatc aattcgtcaa acgacattag
    24421 ttgatctaat caaaaaaggg tttcaagaat acggcacatt gattgaagaa aatctgccaa
    24481 acaaccttgt ggagaaatat cgactgcttg accgagcttc tgctgtaaga agtatgcatt
    24541 ttccaaaaga ccacgaagaa aaccatcaag ccaaacgacg tgtcgttttt gaagagttct
    24601 ttttatttca aatgcgtctt caaggattga aaaaagcaga aaaagcagaa acgaatggtt
    24661 tggagatcct ttatgatgtc caaaaattga aacaatttac tcaaaagcta ccttttgaac
    24721 tgacaaatgc acaaaaacgt gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc
    24781 atatgcagcg acttttgcag ggagatgtag gtagcggaaa aacagtggtt gccgcgattg
    24841 cgttatacgc taccgttaca gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct
    24901 tggcacaaca acatatggaa agcttgcaac agctgtttga tcccaatgaa gtaaccatcg
    24961 cattgattac ggggtcaacg aaagcaaaag aacgacgtga gctccttgaa aaactagagc
    25021 aaggggaaat taacgtcgtg atcggcacac atgcattgat ccaagatgga gtcgaatttc
    25081 agaatttagg tctagttatt acggatgagc agcaccgttt tggcgtgaac cagcggaaag
    25141 tacttcgtga aaaaggctgg cgaccagatg tcttatttat gacagcgact ccgattccta
    25201 gaacattagc tattacagca tatggtgaga tggatgtatc tatcattgat gaacttccag
    25261 ctggacgtat cccgatcgaa acacgctggg taagaacacc tcaattggac agtgtactgg
    25321 attggacgaa aaaagaactg gcaagaggac atcaaatgta tgtcatctgt ccgctgattg
    25381 aagaatcaga agcattagat gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac
    25441 tatttgcacc aaaatatgaa gttggcttgt tacatggtaa aatgaagaat caggaaaaag
    25501 aagtaatcat ggaagccttc aaagacaacc agatgcagat attagtttcg actactgtaa
    25561 ttgaagtagg ggtaaacgtg ccgaacgcga ccgtcatgct gatcatggat gcggatcgat
    25621 ttggattggc acagctgcac caacttcgtg gacgtgttgg acgcggaagt gatgcttcct
    25681 actgtatctt agttgctaat cctaaaaatg aactaggtgt ggaacggatg aaaatcatga
    25741 cagagaccac caatggtttt gtactaagcg aaaaagatct ggaattacgt ggtcctggtg
    25801 aagtatttgg cttccgtcaa tctggtctgc ctcaatttgc gattgctgac ttggtgacgg
    25861 atggaaatgt tttggaggta gccagagaag aggctgcagc cctttggcaa ataaaggatt
    25921 ggcagatgct tcctgagtat cagcctttag cgcaaagcct ccaaatagaa aatcaggata
    25981 atcgttattt cgattagcag actgtgctat actttatact gatgacggaa aaaggagtgg
    26041 aaacaatgaa aattgccgta gatgcaatgg gcggagatca cgcacctcaa gcaattgtag
    26101 aaggcgtggc tttagcgcag caagattttc cagaagtaga attcttactt tacggaaaag
    26161 aagcagaaat caagaaatac ttaacaaatg aaaaaaacat cacgattatc catacagacg
    26221 aaaaaatcaa tagtgatgat gagccagtaa aagcaattcg acgaaaaaag actgcatcaa
    26281 tggtccttgc tgcacaagca gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga
    26341 atacaggcgc gctactagca gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac
    26401 gccctggctt gatgtctacc ttgccagtag tagggaaaga aggtgccggt ttcgatatgc
    26461 tggatcttgg cgctaacgca gaaaacaaac cagaacattt gttgcaatac ggtattttag
    26521 gttcttttta tgcacgtaaa gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca
    26581 acggaacaga agcaacaaaa ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga
    26641 atgaaacaag cttgaatttt attggaaacg tagaagctcg tgagctactc aatggtgtgg
    26701 ctgatgtagt ggtcacagat ggatttacag gcaacgctgt tttgaaatct attgaaggaa
    26761 cagcaatgaa tatgatgaat ctattaaaat ctgctattct aaatgaaggg atcaaaggaa
    26821 aaatgggcgc tatgctttta aaagacggct tacgttcttt gaaagcagaa atggattatt
    26881 ccaaacatgg cggtgccgtt ttgtttggct tgaaagcacc agtcattaaa actcatggag
    26941 caacaggccc cgatgctgtt cgctatacga tccgccaaat ccacacaatg cttgagacag
    27001 atgtagttgg acaattagtc gaacaatttg aaaaaagcga agaatagtat ttggatatct
    27061 gaagcgatcc gttccattga aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag
    27121 ccatggtgta ggtaattgac aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa
    27181 gaagtattta acaaagtagc gaaaattatt tcaaatcatt ttgagataga taccgataaa
    27241 gtgacggatg aattgaacat caaagatgat ttaaaagctg attcaattag tattatggaa
    27301 ttcgttttag agcttgaaga tgaattcggt acggaaattt cagatgaaga cgctgaacaa
    27361 attgaaacag tcggtggcgc agtagattat atcagcagcc atcttaaata atttcaaata
    27421 aaagcaaaga aggataaaaa gctgcatgca gctttttatc cttctttttt taatcttttt
    27481 gacacgtaaa agtcattttt ctgataattc tggcgataaa cagaaattat gttgcaaagt
    27541 aaagcggttt tctatataat tattaataat tcattacaca aagataagaa taacctttgt
    27601 tataaaacga tttattctgt gtaatgtcct tttttattaa gaaaaacttc catttaggaa
    27661 gcagagaggg gtattcgatt gtccgataac caattattag aagttcagaa cctacataca
    27721 ggattccgac tcaaagatga ctattacgat gcagtagatg acgtttcatt tactttagac
    27781 aaaaacgaga ttttagcaat cgttggggaa tctgggtgcg ggaaaagtac cttggctact
    27841 acgattatgg gattacttga tcctaataac acaaaaatta caggtgagat tttatataac
    27901 gatctgaatt taatcgacct gaacgaaacg ctctataata aaatccgcgg aaatgatatc
    27961 ggaatgattt tccaagatcc gttgtctgca ttaaatcctc tcatgagaat cgaagaccag
    28021 atcaaagaag gactttccta tcacacaaag atgaatgcag aacagcgtca agctcgtgca
    28081 ctagaattgc tagaacaagt agggattcct aatcctgcga gagttggacg ccaatatccc
    28141 catgaactat caggcggtat gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa
    28201 cctccaatcg tcattgcaga tgaaccgacg acagccctag atgtaaccat ccaagcacag
    28261 attcttgatt tactgaaaga ccttcaggaa gaaacaaaaa cagggatcat cttgatcact
    28321 catgacttag gagtcgtagc agaaatggct gatcgagtgg cagtgatgta tggcggacag
    28381 ttcgttgaag tagcaggtgt aaaagaactg tttgatcatc ctaagcatcc ttatacacgc
    28441 tctttactga actctatacc acaagaagga aatcatgatg cagaactcca tgtgatcgaa
    28501 ggtgtcgttc cttctctgaa aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt
    28561 ccatggatac cagcaagcga tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac
    28621 cacttggtac gttgctcctg ctataagcat ttccacttta gagacgaaaa aggagaggtg
    28681 tagatgacag aattaatcac aatcaaagac ctgaaagttc attaccctat tcgcagtgga
    28741 ttcttcaatc gagtaacgga tcatgtatat gctgtagatg gtgtggattt tattatcgaa
    28801 aaaggaaaga catatggttt agtgggagag tctggctctg gaaaatctac tacgggaaaa
    28861 gccgttgtgg gattagaaaa ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta
    28921 acgaagcgaa gcaaccgcaa aaaaatgggt tataacaagg atgtgcagat gatcttccaa
    28981 gattcaatgt ccagtttgaa tcctaaaaag cgagtgttgg atatcattgc tgaacccatc
    29041 cgaaattttg aacggttaag cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat
    29101 atcgttggga tgccggaaga tgcgctatat aaatatcctc atgaattttc aggcggacaa
    29161 cgtcaacgtc taggagtagc ccgtgctgtt gctaccaatc caaaactgat cgtagccgat
    29221 gaacctgtat ctgctctgga tctatctgtt caagcgcaag tattgaattt catgaaacga
    29281 atccagcaag aatacggcct cagctattta ttcatttcac atgatttagg tgtagtaaaa
    29341 cacatgtgcg acaatatcgc aattatgtac aaaggtcgat ttgtagaaat cggtacaaga
    29401 gaagacattt ataatgaccc gcgacatatc tatacgaaac gtctgctttc agctattccg
    29461 caaatcgatg tagaaaatag ggaaagccac aaagaaaatc gacgaagagt agaacaagag
    29521 tatatccaaa accaaaaaga atactatgat gcgactggtc gagtctacga tttgcgtacg
    29581 atcacaacta cacacaaagt ggcgttgaaa gatggaggtg caagctaatg tggaaaacga
    29641 ttctgcgacg tgttttattg atgatcccgc aagttattat tttaagtgtt ctgatcttct
    29701 tattagccca agcgatgccg ggggatccat ttaccggttt gatcaatcca aatcaggatc
    29761 cggcagtgat cgaacagatg cgacaagcag ctggcttgaa tgacccatgg tatgtccagt
    29821 acttccgttg gatcggaaat gctttgcaag gcgattttgg tcaaagtttc ttatacaaac
    29881 gctctgttgc tgacttgatc ggcgaacgga tcatcaacac tttatatcta tcgatcttga
    29941 cagttgtcct tacttatttg attgctgtgc ctctggggat gcttgctggc cggtatcaaa
    30001 attcaatctt ggataagatt gtcgtaatct acaacttctt tagttttgct gttcctttat
    30061 ttatcttcgg cttgatcatg ctatttgttt ttggttatcg tttaggctgg ttcccaacaa
    30121 gtggatcaca aacactaggt ttgcaaggtg gatttatcac tcaatggata gaccgtttga
    30181 aatatattct gttaccatca attacccaag catttttggc gactgccgtc acaatccaat
    30241 atctgcgaag tgaagtaatc gattcgaaat cgctcgattt tgtcagaaca gcccgttcca
    30301 aaggggtacc gacgaataaa gtattcagtc gacatatttt ccgaaatgca gcgttgccga
    30361 tggcttctca aatggggtat gaaatcactt cgttgattgc tggttctgta gttatcgaaa
    30421 agatttttgg ttatccggga gtcggaaaac tatttattga ttccatcggc caacgggact
    30481 ataccgtgat cacatcctta gtattgattt taggaatcgc gacgctagtg gggacattac
    30541 tttcagatat catcatgagt atcgttgacc cgcgtattcg gattcaataa aaccaatcag
    30601 aaaggagaat ggatcgatga gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc
    30661 tatggggata cgaatgattg ctcgagaatt taaaaaagat aaaattgcta ttttttcatt
    30721 aggtttgcta gtggttttat tattagtgat ctttatcggt gcgatgctga ccgatcaaga
    30781 caaagtgatg tatgttagta tcttcgacaa atacgctgca ccaggaacag tttcgacaca
    30841 aggacaaaag ttcattctgg gagcagatga aggcggacgt gatgtattag gacaattgat
    30901 cataggtgct agaaactctg ttacgatcgg atttgcgatc acgatcctta cttcgatcat
    30961 cggggttgga ttagggatca tctctggcta ctacggaggg atcattgaca acatcttgat
    31021 gcggatcgtt gattttatca tgattctacc gatcatgctg atcattatcg tcttcgtatc
    31081 gattatttcc agatacaatg tctggtcctt tatattcatc atgagtgcat tttattgggt
    31141 agctaaagcc cgattattcc gaagcaagac attatctgaa gcaagaagag attatgtcag
    31201 tgcctcaaaa acaatgggaa ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa
    31261 tctaagttca ttaatcatta ctaatttgac gatgaacttt gcggcaaaca tcggtatcga
    31321 gacaactttg actttcttag gtttcggctt gccggcaaat gtacctagtt taggtacatt
    31381 gatcggttat gcaagtaacg gagaagtctt agtgaatcgg caatggatct ggttacccgc
    31441 atcaatcctt attttagttt tgatgttgag tatcaattat gttggacaag cattcaagcg
    31501 ttctgcagat gcgcgccaac ggttaggcta gtatagaagc gaagggggaa ataggaatga
    31561 agaaaacgat ttttggattt gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg
    31621 gcggaggtac agatacctct ggaaacaact ctggaggcaa cggcaataac aaagaggaat
    31681 taacttttcc aattgcaaca aaaaataatg atgatgcaat cgaagacggc gaattagaag
    31741 ctgcggtcgc aacggacagt cagtttaaag gattgttcca gtgggagttt taccaagatt
    31801 catatgatgc agcttttatg gctccttctc atgaaccgct atttgcaaac gatgacgatt
    31861 tcagaatcac agacgacgga gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga
    31921 caatcaaagt aaaagacaac gtcaaatggt cagatggtga agatgtaacg gcggacgatg
    31981 tgattttccc ttacgaaatc attgggaata aagattacac tggtatccgt tatgacgaca
    32041 ctttccgtaa catcgtaggt atggaagaat atcatgatgg aagtgccgac acaatctccg
    32101 gaatcaaaaa aatagacgac aaaacagttg aaatcgaata taaagaagta aacccaagca
    32161 tgcttcaatc gggtggtggt atctggtcat atgcagcacc aaaacatacg ttagaaggtg
    32221 tagcaatcaa agatatggaa tcaagcgatc aagtacgtaa aaatccagtg acttttggcc
    32281 cttattacat gagtaatatc gttgcaggag aatcagtaga atacttgcca aacgagcact
    32341 actggaatgg tacgcctaaa ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg
    32401 caactgaagc attgaactct aaattatatg atatgatttt ccaaatgcca acagatactt
    32461 acgataccta taaagaaatt gctggctata caaacttagg ccgtgaacaa acttcttata
    32521 cttatctagg attcaagtta ggtaaatgga atgcagatac aaagagtgtg gaatacaatc
    32581 cagattcaaa aatggctgat aaatcattac gtcaagcaat gggctatgca ttagataata
    32641 atgcagtagg tgaacgtttc tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc
    32701 cagtattcca gtcataccat gatgatgaga tgaaaggatt cacacaagat ctagacaaag
    32761 cgaaaaaact attagatgat gctggctaca aagatgtgga tgacgatggt ttaagagaag
    32821 acaaagatgg aaataaacta acaatcaact ttgcttcgat gtccggtggg gaaacagcgc
    32881 aaccattggc agattactat atccaacaat ggaaagaaat tggtttggat gtccaataca
    32941 caacaggtcg tctgatcgaa ttcaattctt tctatgataa attagaaaac gatgatcctg
    33001 aaattgatgt ttaccaagct gcttggaata caggaactga tccaaatcca agtggactat
    33061 ggggaccaaa tgctgcgttc aactacactc gttatgaatc agaagaaaat acaaaattga
    33121 tcaacgatat cagttcaagc aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa
    33181 aatggcaaca atatgcattt gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag
    33241 tattgccagt caacgaccgt gtcaaagact gggattggtc ttatgatgta ccaaacccat
    33301 gggcaaatgt ttctgttaca gcagattcac gttcataatc actaaaaatg accgaaaaag
    33361 ggcgatgtcc tttttcggtt ttttgatatt tttctgttta tttctctaat attcaggtca
    33421 aggcgctgat ttcatgactt ctccaataaa cggtgttcaa agtccagttt ctcggtatta
    33481 agtcaaattt atgcaaaaat atggaaagcc attttcacaa aattttttct tcatactcga
    33541 aactaaacga atttttcaca acttctcgtc aatcactagg attattaaag ctttacttac
    33601 cttttgaccg aaccatttca aatttgacaa aaaaccagta taataaggaa gtatcgaaaa
    33661 aatatccata aaaggaatgt ggaaaatgga caaccagctg acaaaagaac taaaagaaaa
    33721 ctataacatc gtttttcacg atctaaattt gcttgaacaa gcttttaccc attcatccta
    33781 tgtgaatgag catcgcaatc tgcaattatc ggataatgag cgacttgaat ttttaggaga
    33841 tgccgtttta gaactgatgg tttctcagta tttattccgt ttatatcctc atttgccaga
    33901 aggaaaattg acaaaaacac gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc
    33961 caaagaatgt cactttgatc aatatgtttt gttgggcaag ggagaagaga attcaggagg
    34021 acgtacgcga ccagcattgc tttgcgacct attcgaagct tttttaggcg cgttatatct
    34081 tgaccaggga ttcgacacga cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa
    34141 agcaggtgct ttttcacatg agatggatca taaaacaaaa ctacaagaag tcttgcaaaa
    34201 atcaggtgat gtatcaatcg aataccgatt gatcaatgaa gaaggtccag ctcatgaacg
    34261 agtattttgg atcgaagttt atgtagatga tcaattgatt ggcactggac aagggaaatc
    34321 gaaaaaatta gcagaacaag ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt
    34381 gagggaaagc tttgtatttg aaacgaattg aaatagccgg ttttaaatca tttgcagaca
    34441 agacagtcat tgattttgaa aatagcgtca cagcagtggt tggaccaaat ggcagcggaa
    34501 aaagcaatat tacagaggct atccgctggg tattaggaga acaatctgct aaaagtctgc
    34561 gaggcggaaa aatgccggat atcatctttg ccggttccga tacccgtaag cagctgaata
    34621 ttgcagaagt cacagtgatt ttagacaata gtgatcatta tctgccattg gagtacaatg
    34681 agatcagtgt aacccgccgt tatcgacgga ctggggaaag cgagtttttc atcaataaac
    34741 aaagctgcag attaaaagat atccaagaat tgttcttaga ttctggatta ggaaaagaat
    34801 cgttctcaat catttctcaa ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc
    34861 gtcgtgggat ctttgaagaa gcagctggtg tcttgaaata caagcagcgg aaaaagaaag
    34921 cagaacagaa gctttttgaa acagaagaca acctcagccg cgtccaagac atcatccacg
    34981 aattggaaga acagttaact cctttggccg cccagagtga ggcagcaaag gagtttttac
    35041 ggctaaaaga aacactgact caaaccgatg tctctttgat ggttgctgaa atcaagacag
    35101 caaaaaaaga ttgggacaac aaacaagcac agcttgcgaa attcaatcta gaattaggca
    35161 aactatctga gtcgatccaa gaacaagaat ccattttggc gaagcagcgt aaagaaaatg
    35221 cgcaagccga tcgtctgatc gaaaaaaatc agcaagtatt attagatctt tcggaaaaac
    35281 tgaagcagac agaaggacaa aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa
    35341 gctcgcaaga atatcaaact tcattagcag aagcacaaaa aaaggttaaa cattttgaaa
    35401 agcttcaaga aagcttgatg aaagcagcag cagaaaaaga aacagagatc caaaaagctg
    35461 aagcaaatct cataaaaaca cagcaagaat tagaaaaata ccaaaaatca acgaaagaat
    35521 tattggcaga attaagagat caatatgttg atttgatgca agaacaagca gctgtaggaa
    35581 acgaactgaa gtatctagaa cgtcaatata tacaagaaac agcaaaaagc aagcagacgt
    35641 tagccaagca atcggaagta gaagcatcag tagaccgatt gatcttacaa aaagaagaat
    35701 tgacacaaaa gcaggcgcag ctaaaatcat ctttaactga aacaaaagag aagttagaaa
    35761 tgatccaaca aaacgggaaa aagttccaag aagcattagc aaaagaacag cctaaaatgt
    35821 atcaattaat gaatcaagtc cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc
    35881 aagaaaacta ttttggtttt taccaagggg ttcgattggt cttgcagcat aaacagcagc
    35941 tttcgggtat tgtcggagca gtggctgaac tgatcgatgt tcctgcagat ttcacgttag
    36001 ctatcgaaac agctttaggt ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg
    36061 ctcggcaagc catcacgtat ttgaaacagc aaagaggagg aagagcaaca ttccttccac
    36121 tgacgacaat caaaccaaga caattaccgg ctcatatatt gacacaagca gcagctgtag
    36181 aagggtttat agggattgcc agtgaacaag tcagttatcc cgatcaaatc caaactgtgg
    36241 ttcaaaacct gctaggaacg atccttttag ccaaagactt aactagtgcc aatgcaatcg
    36301 cgcaaacgat ccgctatcaa tatcgagtgg tttccttaga aggtgatgtg atgaatgccg
    36361 gaggatccat gacaggtgga gcgaataaac gaggaaacca aggcagtttg tttgtacaaa
    36421 atcaagaatt gaaacagttg actagtgaat ttgaagaagc agataaacaa ctccaagcac
    36481 aagaaaaaaa agttcaggag ctgcaacaag aaacagctcg tttagccgaa gaacaagaag
    36541 ttttgcgtac acgaggcgaa caattacgtt ttgaagaaca agaagcgaca aatcagctac
    36601 aaaacatcat aaatgaactt gaacgttttg aaaaagaaaa gcaaatctca acttttgaga
    36661 cacgtgaact gcagcagttt atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca
    36721 aacaaacaga tcttgaatcg caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc
    36781 aagaaagcga ccagatggaa gccagaagag cacaagtaca aagtcaaaaa gcacaagaac
    36841 aagcagatct tgctgtcttg aaagagcagt ttaatcatct gcagatccag ctccgcggtg
    36901 cccgagtcca aaaagcagag gcaaccgaac gtcaagaagc gatagaaaag cagttggcga
    36961 cattgacagc agacttttct gatcatgaag tcacagaaga aagtttggaa aaacaaatta
    37021 acgaattatc tgctcagcga gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc
    37081 gagatagaag gcaaaaggag atcgataagc ttgaagcagt cttggcagag cgtaatcgtg
    37141 agcaaaaagc acgactgtcg gaacaatcca aattagaagt ccaaaaagac cgagctgaaa
    37201 tgattttaga taatcatttg acctatctgc agtcagaata tcagctgaca tttgagaaag
    37261 cttcccaaga ctatcaagaa acaaccgata tcgaagacag tagaacaaag gtttcatcct
    37321 taaaagaaca gattgaaaaa ctgggaccag taaacttaaa ttcaatcgaa caatacgaac
    37381 aagtcagtga aagacataca ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa
    37441 accaattgtt tgaaacgatg gatgagatgg atgatgaagt gcggacaaga ttcaaagaag
    37501 tatttgaagc tatccgtcaa gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta
    37561 aagctgaatt agtactgacg gaaccaactg atttgctgaa aacaggtatt gagattgaag
    37621 tacaacctcc tggcaaaaaa ctgcaaagtc taagtttgct ttctggagga gaacgagcac
    37681 ttacagccat cgcgttgctc ttttccatta tccgtgtctg tcctgttccg ttttgtatct
    37741 tagatgaggt agaagcagcg ttagatgaag ccaacgtgaa acgttttggt cgttacttga
    37801 gcgatttcca agatgacaca caatttatcg tagtcacaca ccgcaaagga acgatggtcg
    37861 cagcagatgt actgtacgga gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg
    37921 tacggatgga agatatcaat gaagaggcga aaatcaacga aacgaaagtg taggaacgaa
    37981 aatgatcaaa ttagtagcaa tcgatttgga cggtacatta ttaaatgaac aaaagctgat
    38041 ttcagatgag aataaacaag cattagcaca agcaaaacag caaggggtca agatcgttct
    38101 atgtacagga cgccccttag ctgcgatggc gcattatctg caagaattag gactggtaga
    38161 tgaaggtgac tacagcatca ctttcaacgg cggtttggta caaaaaaatg atactggtga
    38221 aatcatggaa aagaaagtga tggaagtatc agatatccaa cgcttataca aactggctca
    38281 gcaattggat ctgccactag atgttttgtc tgacaatgtg gttttacagc tgcctagtgc
    38341 cccaaggaag caatccttgt acaatgtgtt gaataagctg ctgcaattcc aaccagcgga
    38401 tataagcgat attacagatg aatttgtgct taataaggca gtaatcgctt atgaccaaga
    38461 agaattagat cctaaaatca aagaaatacc agcagaattc catgaaatgt atgagatcat
    38521 caaaacaaga agtatgcttt tggaatttat gccaaaaggt gttacaaaag cttatggtat
    38581 ttctttattg gcaaaagatc ttggtttgaa acaagaagaa atcatggcga tcggtgatga
    38641 ggaaaatgat ttaccgatga tccaatatgc tggactaggc gtagcgatgg agaatgctgt
    38701 gcctttcgtc aaagaagcag cagatttcgt gacagccagc aatgaagaaa atggcgtagc
    38761 caaagtgatc caaaaatttg tattagagta gggggagtca aatgggattt tttgataaaa
    38821 tcaagcgtgc ttttactggc gaagagaaaa cagaagaagt tgaagtacag gagaagtacg
    38881 acaagggttt agaaaagacg cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca
    38941 attttcgaac agtcgatgaa gacttttttg aagaattaga agaaacactt atcggtgcag
    39001 atgtaggttt tgaaacagcg atacgaatta ccgaagcatt acgtcaagaa gtgaaactca
    39061 gaaatgcgaa aaaatcggca gaagtccaaa atgcgatcat cgagaaactt gtggatctct
    39121 atgaagcgga aggaatcaat gaagtaaatg aactaaatat ccaagaagac ggactaacag
    39181 ttattttgtt tgtcggtgtt aatggtgtag ggaaaacaac aagtattggt aaacttgccc
    39241 atcagttcaa aaacgaaggt aaaaaagtat tgatggcagc agcagatacc ttccgcgctg
    39301 gagcaatcga ccagttagtt gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca
    39361 atgcaggagg cgatccagca gctgtcgtat tcgatgcttt ggaaagagca aagacagagc
    39421 aggcagatgt tttactagtt gatactgcag gccgactgca aaataaagtg aacttgatga
    39481 acgaattaga aaaaataaaa cgagtaatcc agcgggaatt accagaagca ccccaagaaa
    39541 cacttcttgt attagatgca accactggtc aaaacgcgat ggttcaagca aaacaattca
    39601 aagaaacaac agatgtgacc ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg
    39661 gtatcgtact tgctatccgt aatgaattgc atttaccagt gaaattggtc ggtcttggtg
    39721 aaggaatcga tgacttggag ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag
    39781 gattactaaa agaagaataa cccatgtcta aaaagcagga gctgtgacaa aagttgcagc
    39841 tccttgtttg aatgattgtt tttaacatag ctgtgttttt gatgccttca tttttatact
    39901 tatttgtaag cggttctcaa acaatttcgt tctttttctt agactttttg attataatta
    39961 gattcatatg aattggaggt cacttaatga tgaattttaa gcaattatta ttgcatgtca
    40021 atgcgcgccc ttttatcgac caagctcgat ttggtataga acgggaagga cagcgggttg
    40081 atcttgcagg aaatctagca aaaaccgatc atccagcaat ctttggcgat cgatcctatc
    40141 acccctatat ccaaacagat tttagcgaaa cacaaacaga gatgatcacc cctgttaccg
    40201 attctattcc cgaattattt cagtatctcg ctgctgttta tgatgtgact gctcgttcta
    40261 taccgaaaga agagatgatc tggccattaa gtatgccacc tgccttaccg gaaaaagacg
    40321 aagagatcat tattgcaaaa ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag
    40381 caaaagaata cgggaagcga aaacagatgg taagcggtat tcatttcaat tttgaatttg
    40441 gcgatgagtt gctaagaaca ttgttcagcc atcaggaaga atttcaagat ttttccgaat
    40501 tcaaaacaga actttatttg aaaacagcga gaaactttat gcgctatcgc tggatgatca
    40561 cttatttatt cggtgcttca ccaatgagtg agaagaacta ctttttagat gaatcacatc
    40621 cgcaagaacc tgttcgcagt attcgcaaca gtgcgctggg ctatacgaat catccaaatg
    40681 tgaaagtttc ctatgcttct atgaaacagt atttagcaga tatcgagcga atgatcgaag
    40741 aagggaaact ttcggaggag aaagaatttt atacaccgct tcgtttccga ggcggaaaga
    40801 aagtcgcaga tttagcaaca acaggtgttc gttatattga attgcggaat atcgatttga
    40861 atccttatgc aagattgggt atcaatccag agcaagttcg gttcttacaa ttattcctga
    40921 tgtacatgtt atggacagaa gaaaaagaag actgtgacca atgggtagca gaaggtacga
    40981 ctcgaaataa caaagtagca ctagaacaac catcagatca aacagaattt catcaagaag
    41041 gtagagaaat tcttgaagga atgaagcaaa tgctggttga attggattgg ttggattctc
    41101 tttatttagt agaggaagca ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga
    41161 aactctatca agaagcacag ctatcgagtc agcaagaagt tgctgtggca ttgggacatc
    41221 aatattataa agaaagccat gaacgtccct atcagttggc cggttttcgc gaaatggaac
    41281 tttctactca gatatttatg ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag
    41341 atgagtcgga tcaatttttg cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg
    41401 caaacatgac aagtaaggac agctatatcg tcccacttat catggaaaac aaaacagtaa
    41461 cgaaaaaagt cttaaaagaa gctgggttcc gggtaccagg aggcgcagaa ttttcatcca
    41521 tggaagaagc ggtaaaagct tatccgagat ttgccgagca ggcatttgtg atcaaaccta
    41581 aatcaaccaa ttacgggtta ggtatcacga ttttcaagga aggagctagt ctggaagatt
    41641 atcaagcagg tttagccatt gcttttcgtg aagacagttc ggttttagta gaagaattta
    41701 tgccgggaac ggaatatcgt ttctttgtga tcgacggaga agtccaagcc atcatgttgc
    41761 gagtccctgc taatgttatt ggtgacagta tccgaacagt gaaagaactt gttgaagaaa
    41821 aaaatagtga ccctttgcgt ggaacgaatc atcgtgcacc tttagaattg atccaattag
    41881 gtgaattaga acaattgatg ttgaaagaac aagggttgac gatcgaatca gttccccaag
    41941 ccaatcaaat tgtttatcta agggagaact caaatatcag tacaggtggt gattcgatcg
    42001 atatgactga tgaattttct gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac
    42061 taggagctaa gattagtggt atcgatttga ttataccaga taaagaaatc gatcctacaa
    42121 ctgataaaaa agcatatggg atcatcgaag caaatttcaa tccagccatg catatgcatg
    42181 tttatccttt tgcaggaaaa ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc
    42241 ctgaagtatt ttaaaagaaa aagcttttga cagattgtcc tatttgatgt caatctgatc
    42301 aaaagctttt tttgcatgta aaaatttatg tgttttttcg ttttaaaata aacgatccca
    42361 gaagcttttt ttcttttttg gtttttcttt ttcagctggc gaagagtttt cttctgggta
    42421 ttttttttcg atatcaatca caggttcatt tactgcttct tttgctgtta agagcaatcc
    42481 gaattcctca ggatttgcag tgacgtaatc gttgactaca gtgaaacggc tattgttttt
    42541 cgttgctagc tggatatatt ggttttggac agaaaggggt agagccccat tcaagagtat
    42601 ggaagcatct ggatgttttt tgagttcttt taaaaagttt tctttgtttt ttggttggat
    42661 catttcagca acagtcatac taagatagca gcgttccctg aatgtcccta aatatttatg
    42721 ctgttcttca gggttcacta aaggtgtacc ataaagtccc ttatccaaat ggctttttac
    42781 atcatcttgt gccataaaaa ataccctcct tcttctcttt gtctttctta cgattatagc
    42841 atattcccaa taatacctaa aacatatgaa aaagcggttg cttttgttca acgattcact
    42901 taaaataaga atgaaaatca ttctcaatta gaaaggtgga ttggatgcgc tacggacgac
    42961 tagtagcatt attagttatt ttaagtagta tttcattgtt catcggagta tcgaatgtac
    43021 aattgtcaga actgctccag ttagatgggc aaagcttaca aatcttgcta gtgactcgtt
    43081 tgccacgaac gatttgtttg atccttgtgg gagcgaccag tagtatttgt gggttgatca
    43141 tgcaacattt gacccaaaat aaatttgttt caccaacgac tgcgggcacg atggatagtg
    43201 cgcgtttagg tattttagtg gctatgattt tcctacctgg tgcatccttg attgtccgat
    43261 ccttgacagc attttgcttt gcttttgcag gaacattgct ttttttatcc cttacgcgat
    43321 tgttcctcca gaaaaatcaa ttgatgcttc cgttgattgg agtcatgtta gggaatatca
    43381 ttggttcagt tgctactttt tttgcttatc aattccagtt ggtacaaaat atgacttcat
    43441 ggcttcaagg gaattttgcg actgtgatac gaggaaatta tgagttattg tatgctgttg
    43501 ttccattgtt gctcttggtt tggctatttg cttaccgatt tacgatcatt ggtctgggcg
    43561 aatcgtttgc agtaaatctg ggaatagatt accagaagat gcagttttta ggcattggct
    43621 tagtatcatt ggctagtgca gtcatgttga tcatggtagg aagcattcct tttatcggag
    43681 tgatcattcc gaatcttgtc tctagaatat atggagatca agtgcacaaa acaattggcg
    43741 taactgcttt agcaggtagt ttgttcttag tattttgcga tcttgtcgct cgcgtgttga
    43801 tttttcctta tgaaatacca gtcagtgtga tcgttggaat catcggtggg gctatcttcc
    43861 tttatcttct gataagggga cgacgatatg cttaaaaaaa agccatctat ttttattggt
    43921 atgcttgttc ttgttttatt tgttacagga atgtacttga cgatccatac atatggaaac
    43981 tggcattttg catgtgcatt gaggagtaag aaaatttttg catttatcct tgtctcgcta
    44041 gctgtcagca gtgccacaat cagctttcag acaattacgc ataaccagtt tttgactcct
    44101 tcagtattgg gacttgagtc gttatatgtc cttgtccaaa cggtcctttt cttctttatc
    44161 ggaggagtga cgatgcttca gcagacaggt acagtttttt tcttattgaa cgttgggctg
    44221 atggtcgggc tgagtctatt gttatttttc tttcttttga aaaaaatgag agcgaatctt
    44281 tttttattac tgatgtcagg gatgatttta ggtacgcttt ttggtagtgt cagtaccttt
    44341 ttacaagtca tcatggatcc gaatgaatat gatttgcttc aaggcagatt atttgcaagc
    44401 tttggcaata tccagagtca gtatcttttg cctgcttctt tgatcattat cggctgctgg
    44461 tacctgttat ttcgatatcg acatgtgcta gacgttttcc atctcggaaa tgaacaagca
    44521 gtaaacctcg ggatagacac agatcgtttt gaatttttga ttttatgttg tgtcagtctt
    44581 ttgacaggga catcaacggc tcttgtgggt ccagttactt ttttagggtt tattgtcgca
    44641 aatatcagtt atcgtgtctt ttctacttat cgtcatggtc agctatttat cggaagcttt
    44701 ctggtagcta tgctgtttct gacaggagga cagctcgcag tagagcagat tttcggctgg
    44761 aatacaacag tgagtgtcgt cgttgaattt gtcggaggaa tttattttgt cacaaaattg
    44821 attcgcgaaa ggaagagtat cctatgattg atttacaaaa ggtcaataaa ctgtaccatg
    44881 gaaaatcagt ggttaaagat gtacagttaa cgattcctga aaagaaattg actgctttta
    44941 tcggtccaaa tggtgctgga aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa
    45001 aagatacagg tgaaatctat ttagaccata acgaagtaaa ggcttggaaa tccaatgaat
    45061 tagccaaaaa attatcgatc ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga
    45121 aagaattagt agaatttgga cgatttcctt atacgaaagg aaaattgacg acaaaagacg
    45181 aggaaatcgt tcaggaatca ctggaacacc ttgggttaga agaaatagcg gatcaatcga
    45241 ttgacactct ttcaggcggt caactccaac gtgcgtatat tgcaatggtg ctagcgcaag
    45301 acacggatta tattttactg gatgaacctt tgaacaatct agatatgaat tttgcggttc
    45361 aaatcatgca gattttaaaa aatttagtac aagaaatcgg gaaaacaatt gttattgttc
    45421 ttcatgatat caactttgct gcaagttatg cagacgaaat tgttgcaatg aaagatggac
    45481 agttatttac gcaaggaacg acccaagaaa tgataaaaaa agatgtattg gatgaattat
    45541 acgaaatgga catacggatt tgtgagattg aaggccgcag attctgtctt tatttctaaa
    45601 actaacatta ggagagaaga gatgaaaaaa ttagtagtag gtatcttgat tctagcatca
    45661 tttggtttag cagcatgtgg aaatagcaac aacaccagtc aggcagacac aaaaaaaagc
    45721 agcacacaaa ctgaaactac attgacgata acagatagta atggagacca aatcgaggtg
    45781 ccaaataatc cagaaaaagt cgtcgtattc gacaatggtt ctttagatac gatggatgct
    45841 cttggtgttg gagataaggt agttggagca gctacaagca gccttcctga gtatctttca
    45901 tcctataaaa aagtagaatc agcaggtgga ataaaagaac cagacttaga aaaaattaat
    45961 cagcttcagc cagatctaat catcatttct ggccgacaaa gagattttca aaaagatcta
    46021 agtcaaattg ctccgaccat tttcctttct ttagatgcga aaaatccatg ggaatctttc
    46081 cagcaaaatg tcactgcttt aggggagatc tttggtaagc aagaagaagc taaaactcaa
    46141 ttagaggaat tatctagtgc aatcgatcag acgaaaaaga aagcagaagc tactgacaaa
    46201 aaagcactag tcacacttgt gaatgaaggg caattatcag cctacggatc tggttctaga
    46261 ttcggtttca tccatgattt atttggcttt gaacaagcag atgatcaaat cgaagcatcc
    46321 actcacggtc aaagtgtttc ttatgaatat gtgctggaaa aaaatccgga tatcttattt
    46381 gtagtagaca gaacaaaagc tattggtgga gacgacagca aagatgatat ttctgccaat
    46441 gaactggtag cacaaacgaa tgctggtaaa aatcagcaga tcatctccct tgaaccagat
    46501 gtctggtatt taagcggggg cggtttagaa tcaatgaaac tgatgatcga agatgtgaat
    46561 caagcattta aatagcataa ataacagagg attaaactct catactatgt aacaataatg
    46621 tttcttacat tcttaaatag caagagccta tcctcaaaga agttatcaaa aaccatccgt
    46681 aaaatcgtat tgatgatttt acggatggtt tttatttatt tgagaaatct tttttcaacg
    46741 tgaattcatt atctacatca tacgggttga ttctagaatg gggagtggca aaaaatagtg
    46801 tgatccattt tttcagcatc aagatcgcct cctttgattt gaatcaaagg tacaaagcga
    46861 aacttagata aaacttaaat ttagatattt ttattttgta ccgatctctt ctttaaacga
    46921 tgttccatct gctgcttctc ggcaataagt ccactagact agaaaatatg agaagctatt
    46981 ttctgtccag cgttcttatt actcaaagca aatcgcagtt gtcacaatct cttctaaacg
    47041 atgttccatc tgctgcttct cggcaataag cccactagac tagaaaatat gagaagctat
    47101 tttctgtcca gcgttcttat tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac
    47161 aatgttcaat cagctgacct tcggtattag ctcaaagcac tgatttcaca acctctattt
    47221 aggcatgtgt ctcagcaagc ggttgatagt tgatgatctg catttttcga taaaaatcgg
    47281 cgggaagctt actccaccgt tttaataatt gatagaaata actctcttct gctttgattt
    47341 tatactcgct taatatcaat ccaaaactat tcgttttttt tgaagctaat tttttataaa
    47401 tatccaatgc tttggtttta tcttcattga caaagagtgt ttttacttca atataagaac
    47461 cctcgatatt ttgtgtttct tcgataaaat agatgttttt tatatattcc ttcatagtga
    47521 ttcctccaaa gaagtctttt atttgataag tttactctac cgaagagttg ttaataatcc
    47581 gtgaacaaaa agtaattctt tttccaatag ttgttaaagg ttttttattt tttatagtat
    47641 tttttgttat ttaagaaagg aataaggtta aacaaataac aggttgcttt ttgggtcttt
    47701 ttccgttcaa gaaactgaac gaagaaaagg gaaagttgtc tcttttgtga taagagaaat
    47761 cataataaac gaatgactta ctttccaata aattgagaac agtcagaacc agacaaatta
    47821 gttgcatctg atgaataaag tgattattct atgacatgag gtgatacaga tgaaattaga
    47881 agtgacaaaa gaagcacaag aagtattgaa gaataaatta gaagcagacg atcaactttt
    47941 attagatatc gaaaacggtg acggtccatt tgcagaaagc caagtcagtt gccaattgga
    48001 tacggcattt cgattgatca ttgtcaaaaa agatacacaa acagatctaa gtctttattc
    48061 tgtagtggct gatacaccag ttggaccaat caaaatcaaa gacagtgcaa tactttacat
    48121 ggatgatcca tccacacttg ctttagaacc aacttataat agtttacaat taaaaggacc
    48181 aagcggcttg agaaaaggca acttgcaagt tgttcgaaaa gactagaggg ataaaatggg
    48241 aaaattggcg atcatcagcg acctacatgt ggacatcaat aaattcggcg aatcagagct
    48301 gatgcagctt tggcaagttt tgcaaaagca caagatcact cggcttcatc tagccggaga
    48361 tacggctaat aaagtagacc gttgcctagc tgttgtcgaa tttttcgtca ataaaggatt
    48421 atctacgaca tttcatttcg gcaatcacga gttggcagat gtgcccaatg aacagatgat
    48481 ggaccatttt ccagacccac attttttaaa tgaacggtat attgctttaa atgagcagac
    48541 cgttctttta gggatgaatg gctggtacga ctatcagttt tccgaattga aagattacga
    48601 ggcaatcgta cgaatgaagc gtttgtattg gtatgatcgg ttcatccagc gtgggaaaac
    48661 agatctcgag gtcaatgcag aaatgcttgc agctgcaaaa aatttgctag accagctgga
    48721 agcaaaaaaa cttgaggtga ttttatccac tcatttcgtt cctaaacggg catttatcat
    48781 gtatcaatct gctccttatg agcgttggaa caaattaaat gcatttttag gatcagaatc
    48841 attcggagaa ttacttgacc gttattcaaa tatcaaacaa gtagtttttg gccatacgca
    48901 tcgtcgcttt gaagataaat ccatcggtca cacgatttac agctgcagac cttttggtta
    48961 ttattatgaa tggcagctga cccgagattt tgtcttgaaa gaacagttgc tagacagcta
    49021 tgatcctatg aaattacgtg tcctcttgcg tgcccatcac ccagcttttc aggcctatca
    49081 aacacaacat ttgcaagagg aatttgaaca agcgatgaca atcgttccgt attgagacag
    49141 cattagtaat gtgtaaaaga aaataccttg taaaacataa ggataagtaa gagcagtaga
    49201 tccatttatc gtggatatgc tgcttttttt gcggaaaata atcagcgaat gtttatttga
    49261 tcggatgatt tgtaactcgc agagtactag atgcaagcgt gtattctttt tttgaacgat
    49321 aatcacaaaa aaaaatataa tatacatttt ttatttaatt ataattaata ttgattgaag
    49381 tctaggcagt caagtcacat tttgatagat aggaggggga cttacgaatt attttaaagg
    49441 ctatgacagc tgtatttcta gattgtgttt gcatcaagtt gcaataaaaa ctagaaatca
    49501 aatcgggctg ataatcattt ataactaatc gatacatagg accaaatata ggtctatgtt
    49561 cttttatttc ataagtatcg taaaacagaa ttttgctatg gattaatcca atcgactgat
    49621 atgtttagta aataaagaaa gaggaatgtc aatgatgaaa aaagaaatcg tattaacagc
    49681 agcaatgatg ttattcagca tggtagcaag tacgactttt gtttctgcaa ctgaagtata
    49741 cccaaaggaa tataacacag aaggaacgat tacatttgaa gcaggagatg agggtgtaac
    49801 tcctcctgtt gatccagaga atcctgatcc caataaacct gtcgatccat cagatcctcc
    49861 aagccctgga acaggagggg cattatcgat tgattatgga tcaaaattca aatttgggac
    49921 tcaaaaaatt tctactgcgg ataaaacgta ttatgcagct gctgatgtga tgaacgatgg
    49981 gtctagaaaa ccgacatatg tccaagtgac agataggaga agtaccttat ctgggtggaa
    50041 attaagtgtc tctcaaccag aacagtttaa aactgccagt ggggatgaac tagttggagc
    50101 acagctgaaa tttacgaaag ggcaggctgt ttctttggtt gatccaacat atacgccgca
    50161 aacggtgaat tctgaattaa cgttgacacc gggaggaaac aatacgttag caattaatgc
    50221 taaatcagga acaggtgtgg ggacttgggt ctatcgattt ggtgcaaatg aaaatgaaaa
    50281 tcaagatgcg gtacagcttt cggtacccgg taaatctgtc aagttagcgc aacaatattc
    50341 cactaaatta gtttggacat tagaagatac acctaacaac tagtttactg aaaagaactg
    50401 ttaaaaataa atacgtagtc atattgtctt gcgaggtaat cgagcaaaaa ttgtcaaagg
    50461 ctaggctaaa tttgtttgga tacgaatagt tcatctagga atttaacgat caggaggaaa
    50521 agatatattg aaaaagagga ggatcgtgct cattttaagc agtctcttag tgactaatat
    50581 ctttccgatc atagggtact ctttggaatt gaatcagttg gagcatggaa atagaagaga
    50641 cgaagaaagc aaactcactt cgacattcga cagtttaata gaatccaacc agacacaaga
    50701 aagcagtgag gatttaagta tttcgagtag tggagagacc actgacaacg tagaagctga
    50761 gggttcggac aaacaaggac tagaagatgc accaatttct gcggttgagc tgcctgacga
    50821 tcccaatatt atttctatcg ataaaatttt tcaaacacct atcggtacta gcacgtccat
    50881 attggaaaat gggaagttac tgcagttgaa cccagcagaa aggtctcaaa gaggagctat
    50941 ttggtcaaat aagaagatta gtttactctc ggattttaca tttaaatctt atttatactt
    51001 aggaaatcaa cgagatagag cgggagatgg catgaccttt acattgactg gcgatcctag
    51061 aatggctagt aatcccagtc aagttattgg atcgccaggt atgggaattg gctcatattc
    51121 tactcgttct ggccaacctt acattgcgaa tgcgctctcg attgagtttg atacgtataa
    51181 aaatagtggt tcttctgatc gaatggatcg agagataact gctgataata gagggcatgg
    51241 acatgtcgct tttgtcacgc ctaaaccaaa taataataat tattctggag agcatactgg
    51301 cgtgacggta gctcctacat ttctttctaa tggcacatgg cgcttgttaa taattaaatg
    51361 ggacgcggag caaagaagtc ttacttatga tttggaaggt gtcggtcact cttctcggat
    51421 tatacctgat ctcattaggc agtttggttc tacagaagta aattgggggt ttacttcttc
    51481 aacaggtact ttttttcaag aaaatgctgt cgctgtcacg cgacttccat cgaatgtcac
    51541 atcaacagct gatgtaaaag tcaacgatag tgattatggg gccatcgctg aagctggagg
    51601 aaacgataag ataactatca gaaatacatt gaaggtcgag ggggattttc ttgaatataa
    51661 gaaaatgcag actagtatcg acctcccaca agaattaact attcccgagc atatcttgat
    51721 caatggaaat caaattgatg ccaaagatat cttgataacc ggaaatcgag tcacgctaaa
    51781 tctgacagat tattttattg ctggagatac gttaataatc gaattggaga caactttgca
    51841 ggaagtaatt cctgaaaaag tactcactat gcattttgaa taccttgaaa acgggaattt
    51901 gattgagcaa tcgaatgaaa taaacctaaa gatcgcaaag ctgaaggaga tagatatcca
    51961 tgtttattat aaagataaag acagtcagat tgatattgct gaaatgaaaa caatcactgg
    52021 gaaaatagga gagaagtata aagaaactcc tattgatatt gaagggtatg tttttgactc
    52081 ggattcagcg aatacagaag gcatcttctc cgaaaataca gaggatatct atttttatta
    52141 cagaaaaggc aaactttatc tctcaactgc tcctcaatat gtcaattttg gaaaacataa
    52201 aatatccagt agaccattaa gtgaattcgg acagttttca ggtgggttga aaattataga
    52261 tgaacgggct tttggaagtt ggaaattaca attgaaacaa gagaaagttc ttacaaatgg
    52321 agattttgag cttccagaag ctctttcctt tgttacctct gaaaatacaa cggttatagg
    52381 gacatccgct gttacgattt tcgaaagtga tcaaaagggt gaaagcgatt tgtcctctct
    52441 tttagattct acagctcatc gtggaatcag aatagatatt cctgtagaaa accaaagaat
    52501 cggaaccttt gaggggaaac tatcttggat acttgcagat gtcccaggaa attaacagga
    52561 agagaagaat ataacaaaat tattgagttt caagaagggc acaggtacca taggctcttg
    52621 tgtcccacag agacaagatt ttgttatagt cttctcttac atatgattaa aggagcgatt
    52681 ttcttgagac caaaacaaca attatttata acactcctag ttattttagg ggcacttttt
    52741 aacaatatat cagtgtcagc tagtgcattt aatttttcag tgacgccgat aacttcagag
    52801 aatcaaatcg acaagagaaa aacttacttc gatcttcaac ttgatccgga tcaggaagta
    52861 gaagtaaaag cggaattgag aaatgataca gaaaaagaag tgaaaatcga tatttctgtg
    52921 aatagcgcaa ccaccaattc aaatgtgatg gttgaatacg gaaaaaacga gattgaaaaa
    52981 gacatgagcc tgatctttga tctggtagat tatgtgagct atccacagat agtgacgcta
    53041 aaacctaaaa gtgtccaaac cgttgctttt catgtcagga tgccgaatga gcgatttgat
    53101 ggtgtattgg ctggtgggat cacattccaa gaaatccaga cggaaaagga ccaaacagaa
    53161 actaaggatc aaagcttatc gattgagaat gaatacacct atattattgc tttgttgatg
    53221 caacagacac tgaacgaagt tgctccgaac cttactcttc atgaagttaa accagatcaa
    53281 atcaatgcaa gaaatgtcat cttagcaaac gttcaaaatg atcaaaaaac ctatatcaat
    53341 caagtagtta ttgaaacaaa aattacaaaa aaaggacatt ctgaagtttt atatcaagag
    53401 gaaaaagaag gattgcagat tgcgccgaat acaaattttt cttttccaac tgctttaaat
    53461 ggtcaaccgc taaccccagg tgaatatcac cttacaatga ctgttttagg aaatgaaaat
    53521 gaaaatggaa aattttcgag aaaaaaagga aatactacga tcaactatac caatcaatgg
    53581 gtatttgaaa aagattttac aatagacgga aaagtagcca aggaattgaa cacgacggat
    53641 gttacgatta aaaaagacaa taattggatt tatatcttag tagcttcact tttcttattg
    53701 tttattttat tatgcatact tttgtttgtt ttgagaaaaa aagaagagaa agaaaagtaa
    53761 ggttaagata acaaatagta aatttttatt attgtaggat ggttgggctc tttttataac
    53821 aatataaaat ataccatttt attaataaaa atgcatacta gtaaatgata taattctaat
    53881 aacaggtttg atcgcgagaa aggccaaata aaacgctctc caaaatgtta aaaaaaagac
    53941 aggacgatgt atattataca aacaagaatc gctgacaaca gtgactcgga tccaggaaat
    54001 cagttttatc cccagctagt tggtgaatgc atggaaagta atatacgtag aaagagctga
    54061 tgactaatga attatgagtt ttttttaagc aaagaagatc acagaagtta ttcattactt
    54121 aaatatttag aagcaagctc aaatttatca gagtcaatat cgaatgttca agaagagttg
    54181 tcgctatcga catttctctt gaaaaaaacg atcgataagc tgaaacatga tttacaaaag
    54241 ttcgatctag agaaaaattt gcgagtaacc gtcagtgaat tggatatatg tctggaaatt
    54301 aatggaaaat gttctagcaa agctctgtta tctcgttata taacggattc tttatctatg
    54361 aaaatggtat tggctttctt tcaggaaaaa tatatctcag tagaaaattt tgctaaacag
    54421 catcacgtga gttattctgt ggcttataaa gtattacaaa gactaaaaag aaatctaaaa
    54481 aaatatcaaa ttttttttga aaagagaaag ttg
//
LOCUS       DAIGUC010000015        54054 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.015, whole genome shotgun sequence.
ACCESSION   DAIGUC010000015 DAIGUC010000000
VERSION     DAIGUC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.015"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(85..2238)
                     /locus_tag="NOB46_000896"
     CDS             complement(85..2238)
                     /locus_tag="NOB46_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCI1057857.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2633..3481)
                     /locus_tag="NOB46_000897"
     CDS             complement(2633..3481)
                     /locus_tag="NOB46_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1057858.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3705..5645)
                     /gene="thrS"
                     /locus_tag="NOB46_000898"
     CDS             complement(3705..5645)
                     /gene="thrS"
                     /locus_tag="NOB46_000898"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCI1057859.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5982..6161)
                     /locus_tag="NOB46_000899"
     CDS             complement(5982..6161)
                     /locus_tag="NOB46_000899"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HCI1057860.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6208..8031)
                     /gene="cadA"
                     /locus_tag="NOB46_000900"
     CDS             complement(6208..8031)
                     /gene="cadA"
                     /locus_tag="NOB46_000900"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI1057861.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8309..10588
                     /locus_tag="NOB46_000901"
     CDS             8309..10588
                     /locus_tag="NOB46_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1057862.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10681..11328)
                     /locus_tag="NOB46_000902"
     CDS             complement(10681..11328)
                     /locus_tag="NOB46_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057863.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11507..12226)
                     /locus_tag="NOB46_000903"
     CDS             complement(11507..12226)
                     /locus_tag="NOB46_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1057864.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12357..13508)
                     /locus_tag="NOB46_000904"
     CDS             complement(12357..13508)
                     /locus_tag="NOB46_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCI1057865.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13725..14465)
                     /locus_tag="NOB46_000905"
     CDS             complement(13725..14465)
                     /locus_tag="NOB46_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1057866.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14469..14792)
                     /gene="rsfS"
                     /locus_tag="NOB46_000906"
     CDS             complement(14469..14792)
                     /gene="rsfS"
                     /locus_tag="NOB46_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCI1057867.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14849..15442)
                     /gene="yqeK"
                     /locus_tag="NOB46_000907"
     CDS             complement(14849..15442)
                     /gene="yqeK"
                     /locus_tag="NOB46_000907"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCI1057868.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15426..16076)
                     /locus_tag="NOB46_000908"
     CDS             complement(15426..16076)
                     /locus_tag="NOB46_000908"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCI1057869.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16086..16397)
                     /gene="yhbY"
                     /locus_tag="NOB46_000909"
     CDS             complement(16086..16397)
                     /gene="yhbY"
                     /locus_tag="NOB46_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCI1057870.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16413..17522)
                     /gene="yqeH"
                     /locus_tag="NOB46_000910"
     CDS             complement(16413..17522)
                     /gene="yqeH"
                     /locus_tag="NOB46_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HCI1057871.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17519..18046)
                     /locus_tag="NOB46_000911"
     CDS             complement(17519..18046)
                     /locus_tag="NOB46_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HCI1057872.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18226..19011)
                     /locus_tag="NOB46_000912"
     CDS             complement(18226..19011)
                     /locus_tag="NOB46_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCI1057873.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(19004..19873)
                     /locus_tag="NOB46_000913"
     CDS             complement(19004..19873)
                     /locus_tag="NOB46_000913"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCI1057874.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19874..21253)
                     /locus_tag="NOB46_000914"
     CDS             complement(19874..21253)
                     /locus_tag="NOB46_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCI1057875.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21261..21680)
                     /gene="fabZ"
                     /locus_tag="NOB46_000915"
     CDS             complement(21261..21680)
                     /gene="fabZ"
                     /locus_tag="NOB46_000915"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI1057876.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVAPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21705..22181)
                     /gene="accB"
                     /locus_tag="NOB46_000916"
     CDS             complement(21705..22181)
                     /gene="accB"
                     /locus_tag="NOB46_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCI1057877.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22184..23419)
                     /gene="fabF"
                     /locus_tag="NOB46_000917"
     CDS             complement(22184..23419)
                     /gene="fabF"
                     /locus_tag="NOB46_000917"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCI1057878.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23438..24175)
                     /gene="fabG"
                     /locus_tag="NOB46_000918"
     CDS             complement(23438..24175)
                     /gene="fabG"
                     /locus_tag="NOB46_000918"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCI1057879.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24187..25104)
                     /gene="fabD"
                     /locus_tag="NOB46_000919"
     CDS             complement(24187..25104)
                     /gene="fabD"
                     /locus_tag="NOB46_000919"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI1057880.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25211..25435)
                     /locus_tag="NOB46_000920"
     CDS             complement(25211..25435)
                     /locus_tag="NOB46_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI1057881.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25488..26450)
                     /locus_tag="NOB46_000921"
     CDS             complement(25488..26450)
                     /locus_tag="NOB46_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCI1057882.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26460..26900)
                     /locus_tag="NOB46_000922"
     CDS             complement(26460..26900)
                     /locus_tag="NOB46_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1057883.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27206..28171
                     /locus_tag="NOB46_000923"
     CDS             27206..28171
                     /locus_tag="NOB46_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI1057884.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRAQLPDLQ
                     EMTFEQKKKELQGLFQGQNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKHFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28228..28458)
                     /locus_tag="NOB46_000924"
     CDS             complement(28228..28458)
                     /locus_tag="NOB46_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HCI1057885.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28544..29431)
                     /locus_tag="NOB46_000925"
     CDS             complement(28544..29431)
                     /locus_tag="NOB46_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCI1057886.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29520..30743)
                     /locus_tag="NOB46_000926"
     CDS             complement(29520..30743)
                     /locus_tag="NOB46_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI1057887.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30760..31806)
                     /locus_tag="NOB46_000927"
     CDS             complement(30760..31806)
                     /locus_tag="NOB46_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI1057888.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYSIRVPIQAISNGIDLEKYRPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31970..33697)
                     /gene="ptsP"
                     /locus_tag="NOB46_000928"
     CDS             complement(31970..33697)
                     /gene="ptsP"
                     /locus_tag="NOB46_000928"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCI1057889.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(33697..33963)
                     /locus_tag="NOB46_000929"
     CDS             complement(33697..33963)
                     /locus_tag="NOB46_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HCI1057890.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34442..36676
                     /locus_tag="NOB46_000930"
     CDS             34442..36676
                     /locus_tag="NOB46_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1057891.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36824..37144
                     /locus_tag="NOB46_000931"
     CDS             36824..37144
                     /locus_tag="NOB46_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI1057892.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37349..37573)
                     /locus_tag="NOB46_000932"
     CDS             complement(37349..37573)
                     /locus_tag="NOB46_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HCI1057893.1"
                     /translation="METEWQIRERKKQKKEEMLRLCRLLDLKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37771..39351)
                     /locus_tag="NOB46_000933"
     CDS             complement(37771..39351)
                     /locus_tag="NOB46_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCI1057894.1"
                     /translation="MNNPELKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39752..41128)
                     /locus_tag="NOB46_000934"
     CDS             complement(39752..41128)
                     /locus_tag="NOB46_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI1057895.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41256..42374)
                     /locus_tag="NOB46_000935"
     CDS             complement(41256..42374)
                     /locus_tag="NOB46_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1057896.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42516..42796
                     /locus_tag="NOB46_000936"
                     /pseudo
     CDS             42516..42796
                     /locus_tag="NOB46_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(42874..43407)
                     /locus_tag="NOB46_000937"
     CDS             complement(42874..43407)
                     /locus_tag="NOB46_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HCI1057897.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43501..44679)
                     /gene="mutY"
                     /locus_tag="NOB46_000938"
     CDS             complement(43501..44679)
                     /gene="mutY"
                     /locus_tag="NOB46_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCI1057898.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44672..45469)
                     /gene="recX"
                     /locus_tag="NOB46_000939"
     CDS             complement(44672..45469)
                     /gene="recX"
                     /locus_tag="NOB46_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCI1057899.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNRGKSQKELLRKIQQTLMTKGFSQEVIQQAMADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45576..46958
                     /gene="rlmD"
                     /locus_tag="NOB46_000940"
     CDS             45576..46958
                     /gene="rlmD"
                     /locus_tag="NOB46_000940"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI1057900.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMICEINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47132..47710)
                     /locus_tag="NOB46_000941"
     CDS             complement(47132..47710)
                     /locus_tag="NOB46_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HCI1057901.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48032..48502
                     /locus_tag="NOB46_000942"
     CDS             48032..48502
                     /locus_tag="NOB46_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCI1057902.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48610..49836)
                     /locus_tag="NOB46_000943"
     CDS             complement(48610..49836)
                     /locus_tag="NOB46_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI1057903.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50590..50790)
                     /locus_tag="NOB46_000944"
     CDS             complement(50590..50790)
                     /locus_tag="NOB46_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1057904.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(50924..51532)
                     /locus_tag="NOB46_000945"
     CDS             complement(50924..51532)
                     /locus_tag="NOB46_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCI1057905.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51617..52087)
                     /locus_tag="NOB46_000946"
     CDS             complement(51617..52087)
                     /locus_tag="NOB46_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCI1057906.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52135..53049)
                     /locus_tag="NOB46_000947"
     CDS             complement(52135..53049)
                     /locus_tag="NOB46_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI1057907.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53195..53998
                     /locus_tag="NOB46_000948"
     CDS             53195..53998
                     /locus_tag="NOB46_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HCI1057908.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
BASE COUNT        15499 a        11446 c         9197 g        17912 t
ORIGIN      
        1 aaatttaagc aaaaatgtga gaagctattt tcacaaaatt tttcttcata ctcgaaacta
       61 agcggctttt tcacgacctc ttttttattt tgccatgaac atatcataat acgcgtccat
      121 tatttcttta gcaatcgtca agtttatgtg gtcttgttcg tctaataagt tcggcaagac
      181 aacactgatg gcaatttccg gattgtctgt tggtccgtat gccacgatat tactattgac
      241 tgtcgcaata tctggatgac cttccgcaac cgtttctgca gtccctgttt ttgcggaaag
      301 gtccattttc gcactggcta atggtttggc tgttgtgtaa ggatcggtac catggacaac
      361 ttggtggaat ccttcacgga ggatcgccat attttctgca gaaatattga ccgtattttc
      421 tactgttgtg ccaatttctt tcttcacttc acccaagttt ccattttcgt cattgccata
      481 gatcgctttg actaggtgcg gctgtactcg tttcccgcca ttagcgactg ttgaagcata
      541 ttgagctaat tggattggtg tatatgtgtc aaactgtcca aatgccaaat cggtaaagtt
      601 acctggagca taccattctt tgccattatc cgcattgaac ttcttcatat aatcaacaga
      661 acgtgagatc ccaggagatt cattcggcaa atcgatccca gtcgttgtac caagaccaaa
      721 ctctttgaaa gagtctctca attgctgata agctttagct tcttcatcta aactaggtag
      781 tcccattcca ggtgtatagt ctagtcctaa catctttaac gccactttga tcatatacgt
      841 attagaagac aattccgatg ctttgactgc atcaagagca acttgtccgc ttcgattaaa
      901 gacagagctt ttttctgaag caccttgcag acgaatcggc tcatcaatca aaacttgatt
      961 tccgctgatc gcgttacttg cccagcctgc tgtcaaagta ccagccttga ctacagaccc
     1021 tggatcaaag gcgctagtaa tcgtgcctaa agcattctcg gtgatttctt tggaaccttg
     1081 ttcatgactg aaaccagtca ttgctagcac ttctcctgtc tgaggattca tagccactgc
     1141 ataagcacca ggcgaatact gtgctttgcc gttgttgatc aatgtttgat aattcctttt
     1201 caaaatttct tctacttttg attggaattc tgcattcata gataacatta aattagaacc
     1261 tttttcccca gagaagattt ctttttgatt cgaaacattt ccttcattat caagggaaac
     1321 ttcatattgg gttttggttc cttgcaggac atcttcatat tgtttttcca aataactttg
     1381 tcctacacgg tcattccgag aataaccttt tgctaggtat ttctctgctt catctgctgg
     1441 aagtccttgc ttttcagtcg tcacactgcc aagaatactt ttcagtgaac ttgctgcatt
     1501 atattctcgt gtccagtctg tgccagtcga aactcctgga agttcagaag cgcgttctgc
     1561 cacaacagct aactcttgat cagtaacacc agagtttttg atatagacag tgtttaattc
     1621 atatgcacta ttcatccgtt taaagatggt tgcaattttt aattgctcct cgtttaaatt
     1681 aatctcatca gctgtgactt tattgaccat cgcactatat tgttcgctgt tccctaattg
     1741 cttttctttt gccgaaagtc tttttgtggc ttctttcaaa tgtttgggat cagccagcca
     1801 aaaatctttt ttatctctat ctgtcagatt ttcatctacc ggaacatcga tcagcgagtt
     1861 cagcttcgtt gcgatttcaa gcaaatcttt agccgtaact tgtgttcctc tcgtatatgt
     1921 gatggcctga ttcgctttat tcgtaactaa agcttttcct gtggagtcgt agatcattcc
     1981 gcgaggagta ctttcttgga ccgtaatcgt agaagtagac ttcactcgcg cctccatctc
     2041 ttcgccgttc acgatctgca aataacccaa tctagcaatc aacgcaacaa ataacgtaaa
     2101 tataatgaaa aaaagaaaat ttaagcgaaa aggaacatgg gaccggcgaa acgttttgtt
     2161 cttaggttct tgtgcacctt ttcttatttt ttctaaccaa gaagtattta atattttttt
     2221 cataaaatct ttcatcattt cctatccttc cgcctattta cattcatgct tcattgtacc
     2281 caaaaacttc ttaataaaca agaagtattt aatatttttt tcataaaatc tttcatcatt
     2341 tcctatcctt ccgcctattt acattcatgc ttcattgtac ccaaaaactt cttaataaaa
     2401 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
     2461 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
     2521 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
     2581 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
     2641 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
     2701 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
     2761 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
     2821 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
     2881 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
     2941 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
     3001 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
     3061 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
     3121 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
     3181 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
     3241 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
     3301 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
     3361 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     3421 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     3481 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     3541 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     3601 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     3661 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     3721 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     3781 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     3841 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     3901 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     3961 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     4021 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     4081 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     4141 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     4201 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     4261 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     4321 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     4381 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     4441 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     4501 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     4561 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     4621 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     4681 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     4741 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     4801 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     4861 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     4921 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     4981 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     5041 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     5101 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     5161 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     5221 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     5281 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     5341 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     5401 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     5461 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     5521 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     5581 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     5641 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     5701 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     5761 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     5821 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     5881 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     5941 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     6001 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     6061 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     6121 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     6181 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     6241 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     6301 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     6361 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     6421 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     6481 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     6541 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     6601 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     6661 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     6721 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     6781 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     6841 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     6901 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     6961 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     7021 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     7081 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     7141 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     7201 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     7261 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     7321 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     7381 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     7441 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     7501 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     7561 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     7621 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     7681 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     7741 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     7801 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     7861 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     7921 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     7981 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     8041 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     8101 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     8161 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     8221 ttcgattcat cagttaaaga gtaccttttt tcgaaaaact atgctatact tttaattcgt
     8281 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     8341 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     8401 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     8461 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     8521 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     8581 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     8641 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     8701 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     8761 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     8821 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     8881 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     8941 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     9001 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     9061 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     9121 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     9181 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     9241 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     9301 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     9361 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     9421 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     9481 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     9541 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     9601 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     9661 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     9721 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     9781 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     9841 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     9901 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     9961 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
    10021 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
    10081 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
    10141 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
    10201 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
    10261 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
    10321 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
    10381 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
    10441 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
    10501 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
    10561 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
    10621 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
    10681 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
    10741 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
    10801 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
    10861 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
    10921 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
    10981 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
    11041 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
    11101 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
    11161 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
    11221 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
    11281 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
    11341 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
    11401 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
    11461 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
    11521 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
    11581 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
    11641 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
    11701 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
    11761 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
    11821 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
    11881 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
    11941 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
    12001 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
    12061 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
    12121 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
    12181 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
    12241 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
    12301 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
    12361 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    12421 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    12481 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    12541 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    12601 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    12661 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    12721 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    12781 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    12841 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    12901 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    12961 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    13021 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    13081 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    13141 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    13201 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    13261 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    13321 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    13381 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    13441 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    13501 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    13561 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    13621 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    13681 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    13741 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    13801 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    13861 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    13921 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    13981 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    14041 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    14101 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    14161 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    14221 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    14281 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    14341 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    14401 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    14461 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    14521 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    14581 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    14641 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    14701 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    14761 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    14821 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    14881 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    14941 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    15001 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    15061 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    15121 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    15181 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    15241 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    15301 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    15361 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    15421 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    15481 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    15541 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    15601 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    15661 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    15721 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    15781 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    15841 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    15901 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    15961 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    16021 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    16081 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    16141 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    16201 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    16261 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    16321 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    16381 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    16441 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    16501 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    16561 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    16621 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    16681 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    16741 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    16801 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    16861 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    16921 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    16981 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    17041 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    17101 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    17161 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    17221 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    17281 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    17341 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    17401 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    17461 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    17521 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    17581 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    17641 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    17701 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    17761 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    17821 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    17881 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    17941 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    18001 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    18061 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    18121 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    18181 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    18241 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    18301 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    18361 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    18421 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    18481 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    18541 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    18601 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    18661 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    18721 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    18781 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    18841 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    18901 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    18961 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    19021 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    19081 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    19141 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    19201 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    19261 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    19321 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    19381 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    19441 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    19501 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    19561 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    19621 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    19681 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    19741 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    19801 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    19861 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    19921 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    19981 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    20041 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    20101 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    20161 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    20221 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    20281 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    20341 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    20401 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    20461 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    20521 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    20581 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    20641 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    20701 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    20761 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    20821 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    20881 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    20941 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    21001 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    21061 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    21121 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    21181 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    21241 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    21301 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    21361 tcaacttcaa ggtataaggt atctcccggt gcaactttct tacggaattt tgctttgtcc
    21421 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    21481 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    21541 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    21601 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    21661 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    21721 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    21781 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    21841 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    21901 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    21961 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    22021 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    22081 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    22141 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    22201 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    22261 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    22321 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    22381 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    22441 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    22501 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    22561 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    22621 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    22681 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    22741 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    22801 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    22861 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    22921 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    22981 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    23041 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    23101 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    23161 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    23221 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    23281 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    23341 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    23401 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    23461 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    23521 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    23581 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    23641 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    23701 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    23761 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    23821 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    23881 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    23941 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    24001 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    24061 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    24121 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    24181 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    24241 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    24301 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    24361 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    24421 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    24481 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    24541 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    24601 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    24661 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    24721 cattttcccg cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa
    24781 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    24841 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    24901 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    24961 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    25021 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    25081 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    25141 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    25201 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    25261 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    25321 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    25381 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    25441 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    25501 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    25561 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    25621 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    25681 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    25741 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    25801 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    25861 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    25921 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    25981 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    26041 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    26101 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    26161 ccttgtactt gtgctgctac agatggcgtc gtgtaatcgg gcgacattgt tgctactaaa
    26221 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    26281 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    26341 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    26401 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    26461 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    26521 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    26581 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    26641 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    26701 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    26761 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    26821 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    26881 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    26941 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    27001 tatatgagct ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa
    27061 tttcttttat tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg
    27121 aacagaacta tagaattcct taaaacttgt ccattatttc aaaatttgtt atagtctttt
    27181 tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct
    27241 gccgggtgtc tatcttatga aagaccgtga tggtaaggtc atctatgttg gtaaagcaaa
    27301 acggctcaaa aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt
    27361 attacgtatg attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga
    27421 tgctttattg ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat
    27481 gaattatttc agtaattata attatgtaca tattaccaat aagggatttg tattaacaga
    27541 tactcctacg gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt
    27601 gcgtataatg gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt
    27661 gcgagcccag cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca
    27721 agggctgttt caaggccaaa ataaaaagct actaacttac ttgaaaaaaa gacaacaaca
    27781 tttcatctat cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt
    27841 tacttatttt attagacgga tccaggaaca aaagcatttt ttaagaacac catcgctcac
    27901 cttcagcatg ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg
    27961 tcaacttgca gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa
    28021 gaaagaagct catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca
    28081 aatcttgatc agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa
    28141 caaaaaagaa gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc
    28201 aacttcaaat gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac
    28261 gatatcgata ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt
    28321 atcggtcgct ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg
    28381 aacttgcagt tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac
    28441 taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa
    28501 gcatagccta cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg
    28561 gtatttttcc ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac
    28621 ctttatctgc caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat
    28681 ccattttttc tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa
    28741 aaccaggtgt gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag
    28801 ctgcacttcc acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg
    28861 catagacaag catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca
    28921 tttttgtatg ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt
    28981 tgaataaagg cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg
    29041 taccattctt tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt
    29101 tttcttttgc tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa
    29161 ctaaaatatg tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt
    29221 ctacatcttt ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt
    29281 ttggtgtatc tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc
    29341 gattatagac agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca
    29401 tgacgcctgt tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc
    29461 ttgcttctat gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt
    29521 tatcttttaa atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt
    29581 cttcgcatct cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg
    29641 ccgaaatgtg tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga
    29701 acttcactgg aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt
    29761 ttccctaatg aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa
    29821 ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca
    29881 ctgacaaaat aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct
    29941 gtgaactgca caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca
    30001 taaggtcctt ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga
    30061 aacccattaa tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc
    30121 atcaaatggt tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg
    30181 atatcagaac gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct
    30241 attacaccat agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc
    30301 gtatgatttg caaataatct agacaagtat tttacatggg attgcctgat cacttttcct
    30361 ttaccgatat aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt
    30421 ttcaacttct tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga
    30481 ataagatcta gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca
    30541 actcttcgat ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc
    30601 aacttatccg cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct
    30661 aattcttgtt ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta
    30721 tcggtaaaaa agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac
    30781 tttttttaat ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc
    30841 ttcaccgatt ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact
    30901 cggtagttct tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc
    30961 catatagcag ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag
    31021 tacgttttgt ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga
    31081 agggaaaaag aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta
    31141 accaggaaac aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg
    31201 aatcgagtac atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc
    31261 aatttctacg aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac
    31321 tttttgatcc ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg
    31381 gcgatatttc tctaagtcga tcccattgga aatagcttga atcggcacac ggatactata
    31441 gctttccaac aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta
    31501 caatcctacc agatattttt ttacgatagg agaaagctgg ttcgatccga taaaggaatt
    31561 tcggaaatct tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc
    31621 tttattgacc atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc
    31681 ttctttttca tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc
    31741 aagcgcacgc ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac
    31801 cttcacctta cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa
    31861 acttaagccc tatttttatc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa
    31921 aaaactggcg tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat
    31981 attcatgaac aagttcaacg acttcttcca tcgtatcgca ttctttcaat gcacgatcag
    32041 caagttcagc cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag
    32101 atgtcgcact cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt
    32161 gatctccagc catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa
    32221 ttacattttt gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc
    32281 gttcgttcat acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga
    32341 agaaatctac ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca
    32401 tgatgccgac ttggatcgta tcagatactt ccttgccttc actgatcaat ttttgttttt
    32461 cttcttcaaa gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca
    32521 tgatacgtaa gttaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca
    32581 tttcgtcgcc ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca
    32641 tttcatgagg taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa
    32701 caactacagg ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat
    32761 cttctgttgg gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg
    32821 cttctccacc attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta
    32881 attcaaaatg cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg
    32941 ctttttgtgc tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag
    33001 gatcgatgat tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt
    33061 tagcagtaat ttcttttgta ccaacgattg ctggaatttc taaagaacgt gccatgatag
    33121 cagaatgtga agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta
    33181 attgtgctgt atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca
    33241 ttgatggatt tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacatcac
    33301 gaatatctgc agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga
    33361 tatacatatc cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat
    33421 tttgcttgat ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata
    33481 cttgcgcttc tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt
    33541 cagtagattt agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg
    33601 ttgccttact gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac
    33661 cgtcactagc ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt
    33721 cattgtttca acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt
    33781 aacatcagaa ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac
    33841 tgatttacct ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa
    33901 tagtgtagct ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc
    33961 catattaatc ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt
    34021 aattcagaga atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg
    34081 ttagatacaa cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt
    34141 tttcatcctt ttcttcacat tttataacaa acgtgtttat tttctttttc ttgtcgcttt
    34201 ctcttctcct gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa
    34261 ttacttgctt ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata
    34321 gagatttcac cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct
    34381 catgaaaaac gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt
    34441 catgctttgt caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa
    34501 tggtcagcgg acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca
    34561 aaatggaggt ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga
    34621 tcttttccgt tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc
    34681 aacacaattt ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga
    34741 aggtttattg ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga
    34801 tcctgtgatc ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac
    34861 caagaacaat cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg
    34921 tttagcacaa aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat
    34981 tcgtttagat gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg
    35041 tatgcaaaaa ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga
    35101 agttcacgaa atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat
    35161 tttaaaacca gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga
    35221 gtaccgcatc atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga
    35281 tgaaccaact gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga
    35341 ctatcatcat gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg
    35401 ttacgtccaa gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc
    35461 taagaaaaac ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga
    35521 agcagaagaa caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta
    35581 tcgcgatcag atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac
    35641 acctgtgatt accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt
    35701 gggtgaatta aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc
    35761 tcatgtcatc ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg
    35821 tgttggatta aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg
    35881 tgtaggtaaa acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc
    35941 aatgattcgt ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg
    36001 ttctcctcca ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag
    36061 aaatccttac agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca
    36121 tatgttcttg caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag
    36181 ctttaaagat acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa
    36241 cgttggtttt ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa
    36301 ctactttaca ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc
    36361 aaaagaaaac ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc
    36421 agcacagcaa cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg
    36481 ctatgatcca tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga
    36541 tggtatcgct gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga
    36601 taaagatgga aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga
    36661 agaaacggct gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg
    36721 tctcattctt ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat
    36781 aagagaaaca agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt
    36841 aacaaacagc cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt
    36901 caaggtctac acagccggaa ataccactat tgtctacact gaagcccctg aacataatga
    36961 aattctgctg atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa
    37021 ttatttctta gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga
    37081 attggcaggc cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt
    37141 gtaaacaaat tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg
    37201 tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct
    37261 aaaattcacg aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa
    37321 acgcttctgt ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta
    37381 cttttctctt ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat
    37441 ggatgattga tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttaaatcta
    37501 ataatcgaca taatcgtaac atctcttctt ttttctgttt ttttctttca cgtatttgcc
    37561 attctgtttc catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt
    37621 atattttttt gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa
    37681 atccgtcacg gctctaaaca aaatatgaga gactgttttt gtttggctat tcttattact
    37741 tgatgcaggg cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattagg
    37801 atatttatcc gcaaaccagc gttctgcaaa ttggttctcg aataagaaca atggttggtc
    37861 gaaacggtca cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg
    37921 atcgatccag cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc
    37981 atttaacata cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata
    38041 ttcttccgtt agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat
    38101 tcctttgtgg aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc
    38161 tggagtaaat gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc
    38221 cccaatctga taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc
    38281 gacgttttct ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt
    38341 tgtacgttcc aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa
    38401 agcgattcgg tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga
    38461 aaattcttcc tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc
    38521 tggtgccaat tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga
    38581 accaaaaaat actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc
    38641 agcctctttg attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag
    38701 aggatgattt tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata
    38761 attttccgga cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc
    38821 tttacccata ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa
    38881 ttcttctaac aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa
    38941 tatcgggatg ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc
    39001 ttttgcacta tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc
    39061 ttcagaaaaa tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc
    39121 aaactgcata acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc
    39181 tgatttggca aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc
    39241 accaaacaat agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat
    39301 cgcaaaagtt ctgcgattgt ccacttgttg ctttaattct ggattattca taacctaact
    39361 ccatttcttc cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa
    39421 gaaagacaat ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta
    39481 aacggcgttc tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag
    39541 ctgtttttgc ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc
    39601 aactactaca actgaatcag tatagcatgg attcatcgaa tgaaaaagcc accaaaccat
    39661 aagagtcaaa tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca
    39721 agcaacacgt ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt
    39781 cttttctgaa gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa
    39841 aaatgacacg gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat
    39901 tatcgacatc aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca
    39961 aataaccagc catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga
    40021 actcatcaat cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa
    40081 gattctcaac ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt
    40141 ctagtgttgc taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct
    40201 gcgtcttttt catttcatat aacagatcat caataaagac cgtttcagga acgaataaag
    40261 gctcctgcat gattttcttg atatctaaat tatcaaaacc gaatttatgg gcagctttta
    40321 gtaaattctt tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga
    40381 ttcttgaata gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat
    40441 caatcataaa tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag
    40501 aaaaaacccc ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca
    40561 tataacgcat ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga
    40621 tacgcgccaa taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac
    40681 caatcaagcg tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa
    40741 tacgtttagg gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa
    40801 tgatatttgc aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg
    40861 ataaagtatt agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga
    40921 ttgtcgatag gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat
    40981 ctccttcatc agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg
    41041 aagctgctaa aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca
    41101 gcgactgact ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt
    41161 agtttacgat agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat
    41221 tttctttgca ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc
    41281 ttgttttcat tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg
    41341 cagattgcgt aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct
    41401 actagaagaa cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta
    41461 ggataaatga tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat
    41521 gcttttaccg gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt
    41581 cctaaatatg gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc
    41641 acaccaatta ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct
    41701 tgtccgctaa tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg
    41761 tttcttcttt tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc
    41821 aacatataga acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt
    41881 ccaacgatcg aacctaaact attggatact ccactaagga attgctgaat gattgtcccg
    41941 taagaaatgt ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat
    42001 tcggctacct cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc
    42061 aatgaggaaa tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct
    42121 gcaactaaaa ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc
    42181 aacagcttga caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca
    42241 aataacgtgg aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc
    42301 atgatcaatg cagctatgat caataattca agcgaccaaa acattagttt agactgtcta
    42361 agtttttcaa acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa
    42421 aaattctttt attctttttt tatttttgaa aacttgccat actttttatt tgttttattt
    42481 tccagtatac tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata
    42541 caatgagcaa tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac
    42601 agggtatgcc tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc
    42661 tgtactcaga taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa
    42721 aaatgaaatt acagcggatg gcgatccttt tgaagatgct ggcatgcctc atatttatat
    42781 gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa
    42841 aatctctcac tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg
    42901 gttataccaa atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc
    42961 aaccagaatc ttcacatttt cttttaggat gaagtcaata tcgttcggat aattcatcat
    43021 tttgctgtgc atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac
    43081 cttgatatcc aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga
    43141 agctagatta caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca
    43201 gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga
    43261 ttcagtgact aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac
    43321 catggtatct cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac
    43381 aaactctcct tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt
    43441 gtgtttgggt gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc
    43501 ctagaaagga ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac
    43561 cttaggaaaa acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc
    43621 ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt
    43681 cagatgacta aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc
    43741 ctgcttttca aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat
    43801 ttctggcttt gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat
    43861 cattggaaat gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata
    43921 cgctccagaa tgattttgaa gagccgcact gatataataa acgtcttttg gctttgcttt
    43981 ttttgttttt acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg
    44041 gatcggacaa gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat
    44101 cattgcttgg ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc
    44161 aaagattttc ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac
    44221 tactcgcatc acgttgccgt caaccgcggg ttctggaagt ccaaatgcga tacttgcaat
    44281 cgcgcctgtc gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg
    44341 catttcccca tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct
    44401 tgagtaataa ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag
    44461 ctcttcaatt gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac
    44521 tctggtttgc tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg
    44581 ccaaggcagg tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt
    44641 tgtttcttta tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa
    44701 tgaatcgctg gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta
    44761 gatttctttt tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga
    44821 ctaaataatc atattctatt tcttgatctg cttcttgcgg aagatcagcc atcgcttgtt
    44881 ggatcacttc ttgagaaaaa cctttcgtca tcaatgtttg ttggattttt ctcaataatt
    44941 ctttttggct ttttccgcga ttttttccaa acgctttttc ggctgtctga tgtgcatttt
    45001 gaacttggtc ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac
    45061 ctttttgctg catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg
    45121 tgcgcacata actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg
    45181 ctacgatttt atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt
    45241 ctttttccga tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag
    45301 ctccgctact cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata
    45361 atcgatagcg tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta
    45421 cgcgatagaa agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc
    45481 tcgaacatat attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag
    45541 aataaaccac agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg
    45601 gacaaacggt tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt
    45661 tcaaacggtt gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa
    45721 tcacgaaagc aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca
    45781 aagatcgcgt agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac
    45841 acttagctta tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa
    45901 aattcaaacc agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc
    45961 cttggcatta tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa
    46021 ttgaagctgg tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg
    46081 ttcaagaacc tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg
    46141 atgcacccat ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa
    46201 tcggtgttaa aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc
    46261 aaaaaaacgc aatgatctgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc
    46321 aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg
    46381 gaaaagaagc cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct
    46441 tctttcaact caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag
    46501 atgtccagcc taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa
    46561 gtgtagcaaa acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg
    46621 atgcaaaaaa aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag
    46681 cagagcaagt tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag
    46741 atccaccacg tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa
    46801 aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa
    46861 gtaaaaagtt caagattgaa tatttacagt ctgtcgacat gtttcctcag actgcacgtt
    46921 gtgaagttgt cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt
    46981 ctgccctgta tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat
    47041 accgtacttg tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg
    47101 acatagtttt tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat
    47161 aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc
    47221 gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt
    47281 ctatttttgt gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg
    47341 gtttggtaat gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa
    47401 tatttaatgt tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta
    47461 aaggctcaaa gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg
    47521 tagcttcgat actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg
    47581 ctgctgatgt tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac
    47641 ctggaatgct aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa
    47701 tctttttcat gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt
    47761 aacacaaaca ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga
    47821 tgcagattat aacagaagta gacgagaaaa gtacaaatag aaaacatgag aaccaaatca
    47881 tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca
    47941 atcatcaatt tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg
    48001 taaactacta ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg
    48061 ggtttgtgtt ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc
    48121 cggagaatat tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg
    48181 gccgatgtgg accttactgt atatattgat gggtatttct ctttatttgt tacttaatca
    48241 caacaacaaa aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa
    48301 ttttatatgg tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat
    48361 tacactttta gttattttct tgtcagtgct tatgtatcag ttgtggctac atcatcgcct
    48421 ggcaatgtgg ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta
    48481 ttcaatttat tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa
    48541 aaagtgccac ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac
    48601 tatttttttc tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc
    48661 attttgttcc tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta
    48721 ctgacttgta tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt
    48781 gttttctgaa taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt
    48841 cgaatcgcca tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt
    48901 aggtaatgta tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag
    48961 aagatcattt tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg
    49021 caactggtct tgtttgattg tttcaaacgc aggggtgtag ttcgtcgcta catcaagcat
    49081 gtcatcccaa tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata
    49141 attgcttacg ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg
    49201 acgacgttgt cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa
    49261 acctttttct ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa
    49321 gtcaatttta ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc
    49381 caaattgatc gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat
    49441 ggccatttcg acaccaccaa atgcataggc atgatttaat ttatctaccg ttccataacc
    49501 tacgatattc gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg
    49561 attaactgtt actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc
    49621 ggtatctaaa cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc
    49681 agaacgtttg gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc
    49741 ttctcccata aatctgattc cgtatgctga taatccggca atcagcaaaa caaatacccc
    49801 taacaaggtt aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc
    49861 taaaatattg tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac
    49921 tttaaaaaac atttttgtgt aacgattact attttttaaa atttctcaaa attcttaact
    49981 atcataccat accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta
    50041 tcttttttta cgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt
    50101 gcagtaaaat gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag
    50161 attatcattc gatttcacga aaatttcttc ctatgactgg tccttttgtt aaacccatct
    50221 tctattcgtt ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattt
    50281 cattaccatc atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt
    50341 taaagtaata gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt
    50401 ttattcaaca tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc
    50461 cttgcttgat aattagttag gacatgtcaa gtgaacaaat gcatttactt agccaaaaaa
    50521 tctaaaaact tcataaatag acaaaaagac acgactctct aagaagtcgt gtctttattc
    50581 aacaaattat tataatttag tcacttcagc agcttgaggt ccgcgtgcac cttcaacaat
    50641 cgtgaattct acttcttgac cttcttctag gctcttgaag ccgtctcctt gaattgctga
    50701 gaaatgaaca aatacgtcat ctccgccgtc tactgtaata aacccaaatc ctttttcatt
    50761 gttgaaccat ttaaccgttc cgtgttccat aaatgtatag cctccaaaaa agttcttgca
    50821 agtaaccttg caagaacatt atacccaatt tagaaaacgc tagcaagctt tcgctctttt
    50881 attttccaaa ttatttttaa gactgatatg acggaggaaa tggttatttt gctgcttcga
    50941 aacgtttgtt tacttcatcc caattaataa cattccagaa tgctgcaata taatctggtc
    51001 ggacattttt atatttcaaa taataagcat gttcccaaac gtccaaacct agaattggtg
    51061 tctttccttc catcaatgga gaatcttgat ttgcagtaga ggtaatagct aattttccat
    51121 tttccattac aagccaagcc catccagaac caaatcgtcc agcggctgct tttttgaatt
    51181 cttctttaaa agaagaaaaa tcaccaaaag cttcattaat cgcttctttt atttctcctg
    51241 taggttcgcc accagcattt ggtgccatga tttcccagaa aaatgaatgg ttagcatgtc
    51301 cgccaccatt gttacgtaca gctgtcttga tatctgttgg aatagcgtcc atatcagata
    51361 ataattcttc tattgttttt tcgcctaatt ctgggtattt ctcaattgct gcatttaaat
    51421 tcgtcacata agtattgtga tgcttatcat gatgcagatg catcgtttct tcgtcaatat
    51481 aaggttccaa tgcgtcatat gcataaggta gatctggtaa tgtgtaagtc ataaaaaaat
    51541 tcctcctcaa tgttttcttt ataatgtcta cattacaaag agtaacaaag agaaggaaat
    51601 tcttcaattg ttatgcctag tcgtcttttt cactttgacc tacttcttct tcaaaaacct
    51661 cagtttcttt aaaaataaac aacttgctga aaatatagtt cgctaggata acaataattt
    51721 gagtgatgat tttcgccaca tactcattgc tgttcataac attgatcaac aataccattg
    51781 cccccatgtc caatccgtaa gaaaggatac ggtagaagaa gaacttaccg cattcaataa
    51841 gtgcatgtgt aaaattcggt gattttgaat ggaataccca aagtttgttc gttacaaaag
    51901 caaacaatac agaacaaaac cacgaaatag aattggataa ggccatactt aaatcaaaat
    51961 attggcgtgc gagagcaaaa ctaacaaaat ttacaatcgt agccaaacca ccaaaaaaga
    52021 gatagactag tatctcccaa tatccttttg cttctaaata tccttttaac tgtcgatact
    52081 gcttcatgag ccaacctacc ttattaaaaa ttcttattta tcatactcta tatttcaata
    52141 actttcatct ttatttaaaa aaattaattt tttttgatcc tttgcctttg tctctgcttg
    52201 gatcgtcaca tgtgtaatac catattttaa ttttaataaa gaaattatac gaggatatat
    52261 cttttcaatc tcgcttagta gctgatcttc aaaatcaata tgtccgtcga aaataattat
    52321 cttttcgcta tactgccaaa tatggacatg atgaacattc tttaccccat cgattgcttc
    52381 aatttcttgt tccatttttt catagtcaat agcaggtgca ctttgtatca aaatagcggc
    52441 agcttttttg atcaccatta tcgcttctat caatatatat atcgaaatga tcagtgtaat
    52501 aactggatcg atccagtaga tatcgaaaaa acggatcaaa attgctccga taatcacact
    52561 taccgaagac agtgtatcac ttaacaaatg caaataacta gattttatat tcaaactttc
    52621 atctgcttct tgtcgtaata ataatactga gaacaaattc gctagcaatc caataactgc
    52681 tactgttagc atcaaatgac tatttatctt ttctggtgaa gtgaaccgct tgaatgcttc
    52741 aacggttaaa aacaaggata atatgatcaa tatgaatgag ttgatgaaag cactcaatat
    52801 ttctaaacgc tggtagccat acgtacgttt tttatttgct tcttttcggg ccattttttg
    52861 tgccccgtaa gaaaaaataa ttgccaatgt atcactaagg ttatggaaag catctgaaac
    52921 aagagacaaa ctccctgaca taatccctcc aataaattct gataaagtga tcaccgcatt
    52981 caaaaccact actccaaata gtttttttga tgatctctgt ggctgtgtag gcactattcc
    53041 ttcctccatt ttatttatat tggatagtct ttagacaaga ataacatttt tttgatattt
    53101 caccaatcat tcagatgttt ccctaaagca cttgtatttc acttgatact tcgctagaat
    53161 tgcaagtgat gacactacta gatgaggagt acttatgaca acaaaacaat taattatcag
    53221 ttcctttata cgattcaaag acctaaagga ggcgagaaat gtcccatttt ggaaagccat
    53281 tgtctatctt ttagttttga gtataattat ggctttgcca atctcttttc aagtttttca
    53341 agtcttaaat aacattcaat tggatgggca aaagattgct actcgcattc ctgattttac
    53401 aatccaaaac gggcagcttc aaaccgaaga aaaagaagga ttcatttacc aaacaaactc
    53461 cattatcttc acatttgatc cagagggaaa acgaacagaa caggacatct ctactgattt
    53521 gatggggaat tttgttagtg tcgggatgtt aaaaaacaaa cttatcatag ctcttcctaa
    53581 tacaggcacg acttctgctt tgttgaacaa taaccaatta gaacttccct acaccaatga
    53641 atctttaaaa aacttaacag gtaagcagct ccgttctttt ttaagtgaag catctatacc
    53701 actttggata aaagtcctga catttatatt ttctatttat cctagttttc tgaatctgct
    53761 gatcactttg ctatttacca acattgctgc ttttctctat gcacgctttc gactaacaaa
    53821 agctactttt cttgattgtt taaaaacatt gatctattca atttcattgc ctactataat
    53881 tgcaacaatc ttgatggtct ttcttccttc ttttgacact agcgccttca ttgcttttgc
    53941 aggaatcttt atttttgctc aagctgtcaa aggatgggca aaaatatcga tcaattaaga
    54001 aataaagaca actcgttatt tctacttaaa tagacccttt tagaggttgt gaca
//
LOCUS       DAIGUC010000016        52015 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.016, whole genome shotgun sequence.
ACCESSION   DAIGUC010000016 DAIGUC010000000
VERSION     DAIGUC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.016"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..233)
                     /locus_tag="NOB46_000949"
     CDS             complement(<1..233)
                     /locus_tag="NOB46_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057909.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDA"
     gene            complement(327..1121)
                     /locus_tag="NOB46_000950"
     CDS             complement(327..1121)
                     /locus_tag="NOB46_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HCI1057910.1"
                     /translation="MSKQCAKCGGKIGLTSYKIKDKQIVCGNCMKKAGYGMTTPYKII
                     RSLNLEDLDKDPSEKRKLNISDHTAQNNHDIGNDRMRTTEEMVEFCLKYGYGKGMTKK
                     WTTHHFNLISDQLNSDEYVIFCFVGLHNYISSTKHDNNYAYALTNKRLIVAQQKMIGN
                     NVQSIILDNLNNISKKRGMLLGTLTIDTLGKVLNVAVDKDTVDRISDSLNEIIYNLKR
                     RNISATNSNTSTISSASEIRKYKELLDDGIITEEEFNKKKQELLDL"
     gene            1767..4574
                     /locus_tag="NOB46_000951"
     CDS             1767..4574
                     /locus_tag="NOB46_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1057911.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            4765..5256
                     /locus_tag="NOB46_000952"
     CDS             4765..5256
                     /locus_tag="NOB46_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1057912.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            5359..6348
                     /gene="manX"
                     /locus_tag="NOB46_000953"
     CDS             5359..6348
                     /gene="manX"
                     /locus_tag="NOB46_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCI1057913.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            6381..7184
                     /locus_tag="NOB46_000954"
     CDS             6381..7184
                     /locus_tag="NOB46_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HCI1057914.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            7205..8119
                     /locus_tag="NOB46_000955"
     CDS             7205..8119
                     /locus_tag="NOB46_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HCI1057915.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            8202..8576
                     /locus_tag="NOB46_000956"
     CDS             8202..8576
                     /locus_tag="NOB46_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HCI1057916.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            8715..8960
                     /locus_tag="NOB46_000957"
     CDS             8715..8960
                     /locus_tag="NOB46_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1057917.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            9132..10196
                     /locus_tag="NOB46_000958"
     CDS             9132..10196
                     /locus_tag="NOB46_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI1057918.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            10442..10867
                     /locus_tag="NOB46_000959"
     CDS             10442..10867
                     /locus_tag="NOB46_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1057919.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            10860..11309
                     /gene="nusB"
                     /locus_tag="NOB46_000960"
     CDS             10860..11309
                     /gene="nusB"
                     /locus_tag="NOB46_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCI1057920.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            11406..12260
                     /locus_tag="NOB46_000961"
     CDS             11406..12260
                     /locus_tag="NOB46_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HCI1057921.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            12261..13598
                     /locus_tag="NOB46_000962"
     CDS             12261..13598
                     /locus_tag="NOB46_000962"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCI1057922.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            13603..13827
                     /locus_tag="NOB46_000963"
     CDS             13603..13827
                     /locus_tag="NOB46_000963"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCI1057923.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            13829..14719
                     /locus_tag="NOB46_000964"
     CDS             13829..14719
                     /locus_tag="NOB46_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI1057924.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            14728..15546
                     /locus_tag="NOB46_000965"
     CDS             14728..15546
                     /locus_tag="NOB46_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HCI1057925.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVTVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            15653..16102
                     /locus_tag="NOB46_000966"
     CDS             15653..16102
                     /locus_tag="NOB46_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI1057926.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            16120..17802
                     /gene="recN"
                     /locus_tag="NOB46_000967"
     CDS             16120..17802
                     /gene="recN"
                     /locus_tag="NOB46_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCI1057927.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(17857..17973)
                     /locus_tag="NOB46_000968"
     CDS             complement(17857..17973)
                     /locus_tag="NOB46_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HCI1057928.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(18046..19002)
                     /locus_tag="NOB46_000969"
     CDS             complement(18046..19002)
                     /locus_tag="NOB46_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI1057929.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            19173..19541
                     /locus_tag="NOB46_000970"
     CDS             19173..19541
                     /locus_tag="NOB46_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HCI1057930.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            19711..20142
                     /gene="mraZ"
                     /locus_tag="NOB46_000971"
     CDS             19711..20142
                     /gene="mraZ"
                     /locus_tag="NOB46_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCI1057931.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            20163..21122
                     /gene="rsmH"
                     /locus_tag="NOB46_000972"
     CDS             20163..21122
                     /gene="rsmH"
                     /locus_tag="NOB46_000972"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCI1057932.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            21127..21528
                     /gene="ftsL"
                     /locus_tag="NOB46_000973"
     CDS             21127..21528
                     /gene="ftsL"
                     /locus_tag="NOB46_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCI1057933.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            21529..23721
                     /locus_tag="NOB46_000974"
     CDS             21529..23721
                     /locus_tag="NOB46_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI1057934.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGIAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            23747..24709
                     /locus_tag="NOB46_000975"
     CDS             23747..24709
                     /locus_tag="NOB46_000975"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCI1057935.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            24723..26084
                     /locus_tag="NOB46_000976"
     CDS             24723..26084
                     /locus_tag="NOB46_000976"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCI1057936.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            26110..27198
                     /gene="murG"
                     /locus_tag="NOB46_000977"
     CDS             26110..27198
                     /gene="murG"
                     /locus_tag="NOB46_000977"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCI1057937.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            27213..28433
                     /locus_tag="NOB46_000978"
     CDS             27213..28433
                     /locus_tag="NOB46_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HCI1057938.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            28589..29914
                     /gene="ftsA"
                     /locus_tag="NOB46_000979"
     CDS             28589..29914
                     /gene="ftsA"
                     /locus_tag="NOB46_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCI1057939.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            29937..31178
                     /gene="ftsZ"
                     /locus_tag="NOB46_000980"
     CDS             29937..31178
                     /gene="ftsZ"
                     /locus_tag="NOB46_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCI1057940.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            31195..31872
                     /locus_tag="NOB46_000981"
     CDS             31195..31872
                     /locus_tag="NOB46_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCI1057941.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            31886..32485
                     /locus_tag="NOB46_000982"
     CDS             31886..32485
                     /locus_tag="NOB46_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCI1057942.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            32500..32787
                     /locus_tag="NOB46_000983"
     CDS             32500..32787
                     /locus_tag="NOB46_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCI1057943.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            32836..33618
                     /locus_tag="NOB46_000984"
     CDS             32836..33618
                     /locus_tag="NOB46_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCI1057944.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            33639..34346
                     /locus_tag="NOB46_000985"
     CDS             33639..34346
                     /locus_tag="NOB46_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCI1057945.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            34608..37406
                     /gene="ileS"
                     /locus_tag="NOB46_000986"
     CDS             34608..37406
                     /gene="ileS"
                     /locus_tag="NOB46_000986"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCI1057946.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(37455..38981)
                     /locus_tag="NOB46_000987"
     CDS             complement(37455..38981)
                     /locus_tag="NOB46_000987"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCI1057947.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(38996..39643)
                     /locus_tag="NOB46_000988"
     CDS             complement(38996..39643)
                     /locus_tag="NOB46_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HCI1057948.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(39827..40156)
                     /locus_tag="NOB46_000989"
     CDS             complement(39827..40156)
                     /locus_tag="NOB46_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HCI1057949.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            40333..41061
                     /gene="sfsA"
                     /locus_tag="NOB46_000990"
     CDS             40333..41061
                     /gene="sfsA"
                     /locus_tag="NOB46_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCI1057950.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            41077..42090
                     /locus_tag="NOB46_000991"
     CDS             41077..42090
                     /locus_tag="NOB46_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1057951.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            42090..43367
                     /locus_tag="NOB46_000992"
     CDS             42090..43367
                     /locus_tag="NOB46_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI1057952.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            43430..46132
                     /locus_tag="NOB46_000993"
     CDS             43430..46132
                     /locus_tag="NOB46_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1057953.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            46284..46601
                     /locus_tag="NOB46_000994"
     CDS             46284..46601
                     /locus_tag="NOB46_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1057954.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            46631..46951
                     /locus_tag="NOB46_000995"
     CDS             46631..46951
                     /locus_tag="NOB46_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI1057955.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            47059..48519
                     /locus_tag="NOB46_000996"
     CDS             47059..48519
                     /locus_tag="NOB46_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1057956.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            48587..48808
                     /locus_tag="NOB46_000997"
     CDS             48587..48808
                     /locus_tag="NOB46_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057957.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            48839..49021
                     /locus_tag="NOB46_000998"
     CDS             48839..49021
                     /locus_tag="NOB46_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HCI1057958.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            49021..49434
                     /locus_tag="NOB46_000999"
     CDS             49021..49434
                     /locus_tag="NOB46_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCI1057959.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            49557..50738
                     /locus_tag="NOB46_001000"
     CDS             49557..50738
                     /locus_tag="NOB46_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1057960.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(50809..50973)
                     /locus_tag="NOB46_001001"
     CDS             complement(50809..50973)
                     /locus_tag="NOB46_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057961.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            51127..51200
                     /locus_tag="NOB46_001002"
     tRNA            51127..51200
                     /locus_tag="NOB46_001002"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51161..51163,aa:Arg,seq:cct)
     gene            complement(51269..>52015)
                     /locus_tag="NOB46_001003"
     CDS             complement(51269..>52015)
                     /locus_tag="NOB46_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1057962.1"
                     /translation="HIRASLKDAVEEGLIPFDPTRKAVIKGKDSLKPKEDKYLDYDQF
                     KSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDIDFEDQIITINKTWNYK
                     LNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEVKNPHNFVFFNLKNGLV
                     SSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNILSVSKRLGHSSLETTM
                     STYLHIVRELEDQDKEKINAVFDSLYKNDN"
BASE COUNT        17277 a         8778 c        11059 g        14901 t
ORIGIN      
        1 gcgtctggca cgtcagtcac gatatcaaac aaaaagtata catccttctt cattctagtt
       61 ttcgcagcag gaattttgaa atagttctta ttagaataat agagattaat taataagcta
      121 tcttcgattg ctaaaaagaa aacttctgaa ttccatactt tataaaaatc tttgataaat
      181 ctattcgaag gatcaaattt aaaccataat tgtgtttttc cttccatcaa cataatgttc
      241 acctcaaaaa gagtatacga acaaatgttt gtattgtaaa tagaaaaaga tgagctaaat
      301 taaatgctca tcttttttga tagatattat aaatctaata attcttgttt ctttttatta
      361 aattcttctt ctgtaatgat tccatcatcc aatagttctt tatattttct tatttctgaa
      421 gctgaggaaa ttgttgatgt attggaattt gtagcagaaa tatttcttct ttttaaatta
      481 taaataattt cgtttaaaga atcacttatc ctatcaacag tatctttatc aactgcaaca
      541 ttcaatactt taccaagagt atcaatagtt aatgtaccca acagcattcc tcttttttta
      601 ctaatattat ttaaattgtc taatataata ctttgtacat tattgcctat cattttttgt
      661 tgagctacaa ttaaacgttt attagttaat gcgtatgcat aattattgtc atgcttagtt
      721 gatgagatat aattatgcaa tcctacaaag cagaagatta cgtattcgtc actgttaagt
      781 tgatctgata ttaagttaaa atgatgagtt gtccattttt tagtcattcc tttaccgtag
      841 ccgtatttaa gacaaaattc taccatctct tcagtggttc tcattctatc attacctata
      901 tcatgattgt tttgtgcagt atgatcagat atgtttaatt ttcttttttc tgatggatcc
      961 ttatctaaat cttctaaatt caaagatctt attattttat aaggagtagt cataccgtaa
     1021 ccagcttttt tcatacaatt gccgcaaaca atttgtttat ctttgatttt atatgaagtt
     1081 aagccaattt tacctccgca ctttgcacat tgtttactca cattagttcc tcctagatat
     1141 cagctttcta ctactattaa tattctatca atagtgacca tactttgacc atacttttta
     1201 gaaagaatag aaaattccaa gatatttaat aatagaagaa aagcactaac atcatgggtt
     1261 cagaagaatt gagagcttat caggaaacag tataattgaa gtgtctgttt atccagtagc
     1321 tcaagaagct taattgaatc ttatgattaa agaggttgtg acaagacttt tgtcacagcc
     1381 ttttttgttt ataaaaataa aagttgtagt ggaggctacg aagtttactt tgtcttttta
     1441 cacttaatat ttttttgcca atttggaatc aggatgtttt gataactatc gttttcaatt
     1501 gatggaagct atattgtttg ctatcagtga aataattata tggtaaacag tgttcttttt
     1561 cttgtttcca ttataaaaat cgtatcggga tttttcgttc ttttaaattg aacatttcta
     1621 tctatccgcg tgttatcaac aaaacaaaat caggtaaata gttgacgaaa cagaaataaa
     1681 tacatagtat tatgttttga agcctaagta caatagtcta tagaaaagga gcgataccat
     1741 tggcaaaacg cattgaccga atttatatgt atgtcaaaga aaaaaccgct catttaacaa
     1801 aggcagaata tgatcaagga gtaacaacac aggaaattgc tgaagtgtta gggattcagc
     1861 gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga aggaaaactg ataaagacag
     1921 acggacgacc agtacgttac atatatcaaa cactcgttac gcacgtaaag ccagttacaa
     1981 aacatgtagt cagttacaaa gaaacgccgg tctctgaaga aaaaaataca ctccaaatag
     2041 atactaagga tatctttgca aaaatcattg gagctaacgg cagcatgaaa aattcagtgg
     2101 aacaggcaaa agctgcgatt ttgtatccgc caagaggatt aaattgtttg attacaggac
     2161 ctaccggatc aggaaagact tattttgcac acgcgatgta tcattttgca aaagcgcatc
     2221 atgtaataga tgaggaaacg gaactgattg ttttcaattg tgctgattat gccaataacc
     2281 ctgagctttt gatgagtcat ttatttgggt acgcaaaagg tgcttttaca ggcgcagatg
     2341 aagaaaaaat ggggattatc gatcaagcgg atggcggtat gctgtttttg gatgagattc
     2401 accggttgcc gcctgaaggt caagaaatga tcttttactt tatggatcat ggaacttaca
     2461 gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt acggatcgta ggtgcgacca
     2521 cagaagaccc aggttcttct ctattagaaa cttttgttcg gcgtatccca atcaatatca
     2581 aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt cgatttagta aaaatcatga
     2641 ttgcccacga agcaaaccgc acgcagcgaa agatttcttt gacagaagat gtagcaaaag
     2701 cattgatcgg cagtgtgacc tatggaaata taggacaatt gaagtcaaat atccagttag
     2761 tatgtgcacg aggatttcta aatcatatgc aatcacccga aatctcgatc acaatcgatg
     2821 atttgacaga agggattcgt agcggattga ttcaattagc aagcaaccgc agtgcaatgg
     2881 cagagctttc taaaatattg gagccaaaga taactgtagc accaaatgat acgatcatga
     2941 aaatccaatc ggactcctat gagttacctt ataatctata tgatatcatc ggagataaag
     3001 cagctttact gaagtcggat ggtttggatc aagaagcaat caatcatttc atttctacag
     3061 atatcaacat ccatctgaag tctttctata aagaccatgg tttttctttt aatgcagaca
     3121 gcaaattagc agaatttgta gatccgaaaa tcatagaagt gaccaatcag atttatgtaa
     3181 tggtcaaaag atctttacca tatgagtttc agcaaaactt tatttatgct atgagcttgc
     3241 atatcagttc ttttttgaaa aaaatcaact taggagaaga acggcatacg aatgataaca
     3301 tccgtgagat ggcttttgat tttccagatg aatatgctgt tgcgaaagaa gtgcgtagtt
     3361 atatcgaaac gtattttcaa gtggagattc cagaaagtga agactattac ttgaccgttc
     3421 tactcgtctc gttacgggca aatcaagcaa gcggcagaat cggtgtagtc gttgcagctc
     3481 acggaaacag cacagcaagc agtatggtcc aagttgtcca acagttgtta gatgcagaga
     3541 acgtacgagc agtagacatg cctttggata tggatccgaa aacagcattg gaccgaattg
     3601 aacgcaatgt acaagaagta gatgaaggaa gcggggtcat actcttagta gatatggggt
     3661 cccttgcgtc gtttaattcg caaattcaaa gagacactgg aattccagta cgtactgttg
     3721 atatggtaac aacttctcta gttttggaaa ctgtacgaaa ggtctcagta ttagggacag
     3781 atctagatat gttgcatgaa tcattgaaaa attttcgagg ttacgcagaa atatcttctg
     3841 tagaatctgt tcaggaagca aaacctattc ataagaaaaa agctgttttg gctatctgcg
     3901 catctggcga aggtacagca caaagaatca aagaattgat cgaacgagcg gtaaacaagc
     3961 gtcaagaaac agaattagaa gttctagctt tgtcgattgt ggaagtgaaa gaagaactgc
     4021 cagttatcca aaaagaatat cagatcatag ctactactgg gattactgat ttgaatatcc
     4081 aagccccatt tattccttta gaacgtttta ttgatcaaaa tatcgaagtc attttggatc
     4141 agttgctgat ggaatcagaa ttggaggaaa ctgaattcat ctccctagat gaagagtcag
     4201 ctaaaaatac gtgtgttgag tttatctctg ataacttcat ctttattaat ggtagtaagt
     4261 taatcgatcc aatgtggcaa ttttctacac aaatctctca gacgacggga atcggcgatg
     4321 aagaatatgg attcaaaatc aacctagtga tgcacacagc aggaatgatc gaacgtatta
     4381 ttcggaatga accattgact gtggaagaaa acgaattgac aaatacaacg aatgatcctc
     4441 tttatagcca attggcagcc tcagttgttc tgttggaaga tcagataaaa gtaaaagtgc
     4501 cgatagaaga aatgtattat ctgctacgtc tagtccataa tcagttagat aaaaaagaat
     4561 acactgtgcc atgaatacac aaaaacgata cacttttata gtgtatcgtt tttgtgtatt
     4621 ggttaagaat cctttaaatt caattagtgt atcgtaaaaa agttggcacg ctttttgctt
     4681 atagtagtgt gtgctaggag gtggttgttc acacagaaat gataggggtt tctgtgaagt
     4741 agtgaggaag aaggagtttt gcagatggat attcgattgg cacgtataga tgatcgttta
     4801 atccacgggc aagtcgcaac agtttggtcg aagcaaacag gtgttgaacg tatcattgtg
     4861 atcagcgatg tagtcgctca agataaattg agaaagtttc tactaaaaga agctgcaccg
     4921 ccggggatca cagcaaatgt aataaccgtg cagaaaatga ttcaaatcta tcatagtgga
     4981 ttattatcac gagcaaaagt gatgctttta ttcaccaatc cccaagatgt tgaagcggtt
     5041 gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg gtatgagttt tactgaaggc
     5101 aaatcaatga ttaccaattt tgtttcagta aatcaacaag atattgattc ctttcgttac
     5161 ttgaacagtc aagaagtgga gttagagatt cgaaaagtac ctgctgacag gaaaatcctt
     5221 ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag aatggttgtt ggaaaaggtc
     5281 aaataattct gttgtaatgg ttagcaatta ttaatatttt tgaatttgtt acaacaaaag
     5341 taaataggag gtataaatat ggtagggatt atcctagcaa gtcatggaca atttgctgaa
     5401 ggaatcttac aatccggttc aatgatcttt ggcgaacaag aaaacgtcaa agccgtgatt
     5461 ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat tggaagaagc ggttgcttct
     5521 tttgataatc aagacgaagt gttattctta gttgatttat ggggcggaac accgttcaat
     5581 caatcaaaca cattattcga agagcacaaa gataaatggg caatcgtcag cggtttgaat
     5641 ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa tggaatctgc tcatgaaatt
     5701 gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag taaaaccgga agaattagaa
     5761 ccggcagaag caccgaaagc agcagttgaa gacgcacaac ctaaaggagc acttccagaa
     5821 ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag cacgtgttga ctcacgtctg
     5881 ttacatggac aagttgcgac agcttggaca aaagcagtgc aaccaaaccg tattatcgtt
     5941 gtttcagatg cagtatcaaa ggatgatctg cgtaagagac taatcgaaca agctgctcct
     6001 ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga tcgaagtagc aaaagaccct
     6061 cgttttggaa ataccaaagc attgctttta tttgaaaatc ctgaagacgt attgacagct
     6121 gttgaaggtg gcgtagacat caaagaatta aatgttgggt caatggcgca ttcggtcggt
     6181 aaagtcgttg taagtaaagt attgtctatg ggacaagaag acgttgaagc gtttgagaag
     6241 cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac ctaatgattc acgcgataac
     6301 atggatgata ttttgaaaaa agcaaaagct gaattagcaa aagcgtaata aataatatta
     6361 aaatttatag gaggcttatc atgtctatta tttcaataat tttagtcgta ttagttgcct
     6421 ttctagctgg tatggaaggt attcttgatg aatttcaatt tcatcaacca ctagtggcat
     6481 gtacattgat cggtttagtt accggtaacc tcgaagctgg tatcgtactt ggcggtacgc
     6541 ttcagatgat cgctttaggt tgggcaaata tcggtgccgc tgtagcacca gatgctgcat
     6601 tagcatcagt agcatcagca attattttag ttttaggtgg acaaggtgtt aaaggtgttc
     6661 cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg gttgttctta acaatgatcg
     6721 tacgtacaat cgctgttcca atcgttcatt tgatggatgc ggctgctgaa gaaggaaaca
     6781 tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt acaaggggtt cgtatcgcgg
     6841 tcccagcagc agcgttgcta tttatcccag cacaaactgt gcaatcattc cttgaatcaa
     6901 tgccagcatg gttaacagat ggtatggcta tcggtggggg aatggtcgta gctgtaggtt
     6961 acgctttggt aatcaacatg atggctacaa aagaagtatg gccattcttc gttattggtt
     7021 tcgttgtagc tgcaatttct caattaacat tgattgctct aggtgcttta ggtgttgcat
     7081 tagctcttat ttacttgaac ctttctaaaa tgggtggttc atcaaataat ggaggcggaa
     7141 gcaactctgg tgacccttta ggcgacattt tgaatgacta ttaatcttga aggaggaaaa
     7201 taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat cgtttagctg ttgcgtggcg
     7261 ctctaccttc attcaaggtt catggaacta cgaacgtatg caaaacggtg gctgggcatt
     7321 ttctatgatt ccagcaatca aaaaattata caaaacaaaa gaagaacgtt ctgcagcatt
     7381 aaaacgtcac ttggaattct ttaatacaca cccatacatt gcttctccaa ttttaggggt
     7441 tacattggct ctggaagaag aacgtgcgaa tggcgcgcct gttgatgatg tagcgattca
     7501 aggggttaaa gtaggtatga tgggtccttt agctggtgtt ggtgacccag tgttctggtt
     7561 tacagtacgt ccaatgctag gtgcactagg tgcttcatta gctatgggag gaaatatcct
     7621 tggaccaatc atcttcttct taggttggaa cattattcgt tgggcattca tgtggtatac
     7681 acaagaattt ggctacaaag ctggttctaa aattactgat gacctttctg gcggattgtt
     7741 acaagacgta acaaaaggtg cttcaatttt agggatgttc gtattagctg cccttgtaca
     7801 aagatgggta tcaatcaaat tcttaccagt tgtatcaact gtaaaattag ataaaggtgc
     7861 ttacatcgaa tgggataaat tgccttcagg tggtgaagga atcaagagtg catttgaaca
     7921 agttaataat ggcttagccc tttctcctga aaaggtaaca acattacaag acaacttaga
     7981 ccaattgatt cctggtttag ctgcattagg attaacattg ttatgtatgt ggttgcttaa
     8041 gaaaaaggtt tctccaatcg ttatcatcct tggtttattc gtagtcggtg ttgttggaca
     8101 cgtcatcgga cttttataat ccataaaaat atagctcggg cgttgtcccg agcttttttt
     8161 atatagtata ctgttcataa acaaatatct ggagggagaa aatggttcaa tcaatcaata
     8221 caaaagtaga cttggtaatt gatgctactt cgtttacggg tctgacagat tacgggcaaa
     8281 tcatgatagg tgataatggt tttgagtttt accatgcgcg agatagacgc aaatatatcc
     8341 aaattccatg ggaagaagtg gattatgtac tagcatcagt catgctaaag ggaaaatgga
     8401 ttcctcgata tgccattcaa acgaaaaaaa atggtacata cacattttct tccaaagaac
     8461 ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga agatagaatg gtacaatcat
     8521 tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat gtttaaacgc aagtaaaaaa
     8581 taaagaaaac ttctaagagg aggttttctt tattttttta ctttgcagaa gaaaatatga
     8641 aatagcaaaa ccaattattt gtccccttta aatcccatat gctaaaattg attagcaaag
     8701 aaggaggtta tattatgagt tggttatgga cattgattgt tggagccgtg atcggagcaa
     8761 ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg tgtaacgaat atcattgctg
     8821 gactagtcgg ttcaagtatt ggacaagcga ttttcggcga atggggacca aaagctgcag
     8881 gtatggcact tattccatct attttaggcg cagtgatttt ggtagcagtt gtctcatttt
     8941 tctttggaaa acgatcataa gtttttacaa aatagtaaac taaaaggagt tgcagcgaga
     9001 ctgtgactcc tttttggctt tatttattta aaataaaaag aagttttccg gaaattttta
     9061 tttaactgtc gtgtacgaag aaaagtttgc tataatggaa aaaagcgtgc aaagaaagag
     9121 ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa aaaaatgcaa gaagaaaatt
     9181 tggattcatt tttggttacc agtccgtaca atcttcgtta cttaacgaac tttacaggta
     9241 cgacaggatt agctgttatt actttggaaa aagcattttt tattactgat tttcgttata
     9301 ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat taaaaatgtc ggacctattt
     9361 ttgatgaggt agcaaactta gtacgcaaag aagaactgca ctcattagct tttgaggaaa
     9421 caacagtctc atttttagaa tattcggttt tagaagaaat catcgatgcg gaattagtac
     9481 ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga tgaagaagaa atcgctatta
     9541 tcgaaaaagc atgtcatatt gcggatatgg catatgatca catcctgaaa atgatccaac
     9601 cgggcatgac tgagattgaa gtcgcaaatc aactagactt ttatatgcgt tctcttggcg
     9661 cttcaggtgt ttcttttgat acgatcgttg ctagcggatt gcgttcggct atgccgcatg
     9721 gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat cacattggac tttggttgct
     9781 attacgaagg gtacgtttcc gatatgacac gtacattcgc tattggtgat cctggggaaa
     9841 aattaaaaga aatttatcaa atagtcttag atgctcaatt agcagttatt gatgctgcaa
     9901 aaccaggaat gactggtgtc caattagatg cagttgctag agattatatt tcaaaacatg
     9961 gttacgggga agcatttgga cattctacag gacatgggat cggtttagag atccacgaag
    10021 gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc aggaaatgtg atcactgatg
    10081 aaccagggat ctacttacca ggaatcggtg gagtacgtat tgaggatgac ttgttgatca
    10141 cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga attgatcatc ttatagtttc
    10201 atcaatagaa gaagtaagcg taaaaatcag tgttcacaga ctttgttata gaaaatcact
    10261 cgatttaatg atacactata gaagaacttt taagctgtaa gagataataa agttgggtgt
    10321 tttctccaat tcatagcagt ttgcagctga tcggcggcag ttttcttacc acgtgatcac
    10381 tatgccgcat catagagaat tcggatgtat ctcgtgctta ggcaaaggga ggaataaata
    10441 aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa gatttaggag agatcgtgat
    10501 cgctcctgaa gtcatcgaag taattatcgg gattgcagct tctaaagtag aaggcgtata
    10561 cggaatgcgc ggaacttttg ccagcaatgt cactgaatta ttaggacgtg cagctcacgg
    10621 aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa gtagatcttt actgttatct
    10681 agaatatggt gtttcagttc ctaaagtagc aatggaaatg caggaacggg tcagccagca
    10741 agtccttttc atgacggata tcgatttatc tgaagtcaat atccatgtag tagctgttgt
    10801 tcctgaaaaa ttagaacaac caacaatcga agaacttttt gaagacgaag aggaagagaa
    10861 tgaataaaga attatcaaga cacgagattc gggaaatggc attgcaggct ttatttccat
    10921 tagacttcaa tgcagaccta acaaaagaag atgcgatttt caacgcaatc gaattagacc
    10981 accgcgacat gatcaacgaa gatgaatcag agtttgttcc tgtttatctt gatacgctag
    11041 ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt gattgaaaaa catttaaaaa
    11101 acaattggca catcaatcgg atctcaaaaa tggatttggt gatcttgcgt atcgcgattt
    11161 ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc tttaaatgaa gcaatcgagt
    11221 tggcaaaaac atttagtgat gaccgttcac gtaaattcgt caacggtgtt ttatccaatg
    11281 tattgaaaga attagaagct ggggcgtaag tcctagcttt tttctatgaa tcatcataaa
    11341 cctgttataa atcgggaaaa ttctatggta gaatgaaaac acaaaaaata tctgggagtg
    11401 gttagatggc agaattgatt aacggaaaag aattagctga aaaaatgcag gcagagattg
    11461 ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc cggattagtc gttttattgg
    11521 taggggaaaa tccagccagc caaatctatg taagaaataa agaacgtgta gcaaaagaaa
    11581 tcggaatcca ttcattggta gagcgttatc ctgagacgat ttctgaagac gaactacttg
    11641 cagaaattga aaaatacaat caagatccta gttttcatgg tatattggtc caattaccat
    11701 tgccaaagca tatagatgaa gaaaagatcc tgttagctat ccgccctgaa aaagacgtag
    11761 acggttttca tccgatgaat ttaggcagac tccttgcggg taaaccggac aagattcctt
    11821 gtactccata cggcatcatg aaaatgtttg aagcttattc tatcgatccg gcgggtaaac
    11881 gagcagtagt tatcggacga agcaatatcg tcggtaaacc gatggctcag ctactcttga
    11941 tggcagatgc aactgttact gttgctcatt ctaaaaccga aaatctggct gaactggcac
    12001 aagaagcaga tattttagtc gtagcaatag gacgtggaca ttttgtcaca aaagaattcg
    12061 taaaaccagg tgctgtagtg atagatgtag ggatgaatcg tgatgctaac ggtaagctga
    12121 tcggtgatgt gaaatttgat gaagtggagc ctattgcagg ctggatcact cctgtgccaa
    12181 agggtgtagg gccaatgact atcacgatgc tgatgtatca aaccgtaaaa tctgccgaag
    12241 cttttggagc aggtgaatag atggcacaag aatatttaac tgtcactaca ttaacgaagt
    12301 atttgaaaag aaaatttgat gccgatcctt atttagaacg cgtatattta acaggcgaaa
    12361 tatcgaattt ccgtttacgt gccaatgccc atcaatattt cagcttaaaa gatgaccatg
    12421 caaaaatatc tgctattatg ttcaaaggag cattccaaaa attacgattc cagccaaaag
    12481 aaggaatgaa agtccttgtc gttgggcgta tttcattata tgaagcggga ggttcttatc
    12541 aaatctatgt agagcacatg gagcctgatg gaataggtgc tttatatcaa gaattggaag
    12601 aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg gcctaaaaaa atgctgccac
    12661 gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg agcggttatc cgcgatatca
    12721 tcacgacggt gaaaagaaga tatccaattg tccaattggt tttgttccca acagttgtac
    12781 aaggaaacca agcagcggac aatgttgtca ggaatatcca gagagtagaa gagatgggca
    12841 atttcgatac aatgatcatc ggtcgtgggg gtggttcgat tgaggattta tggccgttta
    12901 atgaagagcg ggttgctcgg gcgatttatc aagctaatac gccggtgatt tcatctgtag
    12961 gacatgaaac agataccacg atcgctgatt tagtagcaga tgttcgggct gccactccaa
    13021 cagcagctgc agaattagct gttcctgttt tgtcagaaga gttgatgcgc attcaagaac
    13081 ggcaagctag attgcagcag gcgtttgtac gccagatcca gcgcaaacaa gaacggttcg
    13141 agcgtgctcg acgttcctat gtatttcggc agcctgaaag attgtatgaa ggtcagacca
    13201 tcaaattaga ccagttgaaa cagcgattat atcaagctac acagcaaatt tatcatgcga
    13261 aagaaaaaca aacgatcgca ttaagccacc aattggaaca agtggctccg ctttatcgag
    13321 ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg cttagaagag aaaatccaac
    13381 aatatatgaa acaacagcag cagcgttttg ctcaagctgt tcaatctctt gatttgttga
    13441 gtccattgaa aatcatggga agaggctaca gctatacgac gttaaatgat caagtagtaa
    13501 aaagtgtcac cgagattcat caaggggatt tgctgacgat ccattatcaa gatggaatcg
    13561 ttaaaggaca agtacaagag atagacaaag gagaataaaa atatggaaaa tccaactttt
    13621 gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt tagaacaagg agacgttcca
    13681 ttagaatcag ctctagattc gtttaaacga ggaatggaat taagcaaaca ttgccaagat
    13741 acattagcta aagcagaaga gaccttgacg aaaatgatga cagaatcaaa tgaagaagtt
    13801 gattttgacg gaaacgagga aagctgagat gagattaact gacttttcag ctattcatct
    13861 acctgctgta gaaaaagaaa tcttgtcttt tttagatgag catacaacgg atagaggact
    13921 ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa agaatacgtc ccttattact
    13981 tttaacggcc gttgcttcct ttgatgagcc tattgatgtt cccgtctatc aagtagcagc
    14041 tgctttagaa atggtgcata cgtattcctt gatccacgat gatttgcctg cgatggacaa
    14101 tgatgatctt cgtagaggaa aacctaccaa tcataaagta ttcggcgaag cattagctat
    14161 attggccgga gatggtttgc ttacaggagc attccagcta atcagtatgg cacacttagg
    14221 taattctcct aagcttctgc tgcttcagca attagctgtt tgtgcgggat cacaaggtat
    14281 ggttgctggg caagctgcag atatcgaggg cgaatcgaaa aagctttctt tagaagaatt
    14341 agcatttatt catgaaagaa agacagggca tttgattcgt tatgccttgc tggctggtgg
    14401 catattagcg aagcaacctg aagaaatctt attgctactt caacgattag ccgaacattt
    14461 aggtttagct tttcagataa gagatgatct actcgatgtg attggtacaa cgaaaacatt
    14521 agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat acttacccgc gtttattagg
    14581 cctagaaaag acacgtgagg cgttggagat tgagctgtta tccgccaaca agatcataga
    14641 caaattagaa gaggacgttt tttcttttga tggcgggctg atgcgccaga tgatcaagca
    14701 atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac gcgtagatgt attagcggtc
    14761 aaacaaggat tatttgaaac aagagaacaa gccaaacgtt cagtgatggc tggtttgatt
    14821 tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa aaattccagt gagtagtgaa
    14881 ttaagagtca aaggtaaaaa acttccttat gtttctcgag ggggattaaa attagaaaaa
    14941 gcactcaaag catttgatct atctgttgaa ggaaaaacat tgttagatat tggtgcatcc
    15001 actggcggat ttactgatgc agctttgcaa aatggcgcaa aaatgagtta tgctttagac
    15061 gttggctaca atcagctagc ttggaaaata agacaagatc ctagagtcgt cgtaatggaa
    15121 agagtgaatt ttcgttatgc aaaacccgaa gactttacct taggaattcc agaagttact
    15181 gttatcgatg tttcttttat ttcactaaaa ctgatgctgc ctccattaca tgctatttta
    15241 aaagaagagg gagaagtgat tgctttaatc aaaccccaat tcgaagcagg cagagaagct
    15301 gtagggaaaa acggaattgt tcgtgaccct cagacccatc aaaaagtttt agaagacatt
    15361 ttgtcatttg cggcacaagg tggatatgat gtgctggaat taagttattc tccgatcacg
    15421 gggggagaag gaaatatcga gttcttggct cacttgagga aagtacccga aagcggaaca
    15481 atcaattcag ctattaatat ggcagaagtg gtttcaaatg cacacgaaca gtttgaccat
    15541 aaataaattg taactgtgaa aatcaagtga gaagtatgcg gattcttctt tattatacca
    15601 aggaaataag ctatcattga ttaagaagaa tatgctaagg agcgaagacg taatgagaaa
    15661 aaaagatcgg catcgtttga ttactcgatt gttgagtgag caagatatcc gaaagcagga
    15721 agaatttgtt gaaatcctga aaagcaaagg aatatctgtt actcaagcta cgatttccag
    15781 agatataaag gaactgaaac tgatcaaggt accggcttca gatggcggct accgttatag
    15841 cataccagct gaaacaaacg aagatgtaaa tactaaattg gaaaaactat taaaagacgc
    15901 tttcgtggca gttgaccaaa tggaaaaatt tgttattttg aaaacattgc cgggaaatgc
    15961 ttcggcagca gcaaatttga ttgataaacg ttacaagaaa gaattatttt cgattatcaa
    16021 tgatgacgat aatgttttga tgattacacg aactgaagac caggcagttt tattgaagaa
    16081 agacttcctg cattaccttt aagttgagga gcgaatgtga tgctacaaga aatcagtatt
    16141 actaactttg cgattattcc ggaattgcgg ctttcttttc acgaaggaat gaccgcgctg
    16201 accggagaga ctggtgcggg taaatccatt attatcgatg ctttaggtct gttagcagga
    16261 ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa aatgtgtgct tgaagggttg
    16321 tttgaactac caaaacaaga aggattctct gaactgatgg ttgaattagg gatcgaaaca
    16381 gatgaggaca atctgattgt tcgacgggat atgtccttaa ctggaaaaaa tgtttgtcga
    16441 gtgaatggtc atattatcac attagctaat ctgagaagaa tcggcagtta tttagtagat
    16501 atccaaggac aaaacgaaca tcaggaactg ctccagcctg aatcacatct tgctttattg
    16561 gatcgttttg gagatgtagc tttccaacag aagaaaaaga gttatcagca agaatatatc
    16621 tcttatcgtg agctggaaaa aagggtacga aaagtgcagc aaaatgaaaa atcctatgtt
    16681 cagagaatag atatgctcca tttccagcaa gaagaaatag ctgctgctga tttgcaagtc
    16741 ggagaagaag agaaattaaa agaagaaaga gaaaaactta gcaattatca aaaaattgct
    16801 gatggattag ctgcaggtta cggagcactg acgaataatg aacaaaacag tgtagatggt
    16861 gttggcttgg ccgtttcaga actgcaaggg atcgcccatc tagatgtgga gtatgaagca
    16921 atttatgaaa atatccaaag tgcttactat ttgctgcaag atgcaatcgg cgatatgagt
    16981 cgtcagattg atttattgga gttagatgag agtcgtttag aagaagttac gcaacgttta
    17041 gaattaatcc gacagttgaa acgtaaatac ggcgaatcca ttgagtcaat attggcttac
    17101 tatgacgaaa tcaccgaaga gctagcttct tctgattttt cagaaggtca attggacaaa
    17161 atgaaagagg aactagagca aaaagagctt ctacttcagc aacaagccgc agatcttcat
    17221 gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca ttctgcatga attgaaaagt
    17281 ctgtatatgg aaaacactga gtttgaggta cgtttcttaa aagaagaaaa tagacaattg
    17341 aatcatgatg gatttgacca aatcgaattt tacattacga ccaatccagg agagccactg
    17401 aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc ggatgttgct tgctttgaaa
    17461 actatttttt cttctgagca aggtgtgaca agtattattt ttgatgaagt ggatacaggt
    17521 gtgagcggaa gagttgcaca ggccatcgca gataaaattt ctcaaatatc gaaatactct
    17581 caagttttgt gcatcactca tctgcctcaa gttgctgcag tcgccgacta tcaatattat
    17641 attgtgaaag cagtgattga tggacgtacg caaacttctg tttcagagtt gaaaacaaaa
    17701 gaaagagaag aagaaattgc acgtatgctg gctggaagtg agattacaaa actcacactc
    17761 gaacatgcaa aagaactatt gaaactcgca aaaaggacct gagccacctc gcagtggttc
    17821 aggtcctttt cagcagctga tagctatatt ttatttttac atgacactca ttacagcagt
    17881 caatacaaca gatccaatcg ttaaaatcag cattgtccaa atgacaaatt ttgttacttt
    17941 agcaaaagta cttgtttgtt ttttttcacg cattgttttc aacctcgtca ttaattagtt
    18001 gattcaagtg tacaatcttt tttccatttc cacaagaggg cttttttata aaaacttccc
    18061 tttttttaaa taataggtag ttacgataca aataaataat gttaatagaa ctagccatat
    18121 aaaggcatca tccctttcag caataggtaa cttaatgttc attccataga tactgccgac
    18181 gattgtcggt atagttaaaa taatcgttaa agaagttaaa attttcataa tattattcag
    18241 attattcgat acgattgctg aaaaagtctg attcatttgt tctactagtt ttaattgaat
    18301 gcgagaagta gtcattgcct gctctgtttc caccaataca tcacgtaaat gatttttcaa
    18361 agcatgattt tcttggaaaa gtttattttg cgctagttct ttcaatgcat ctaaattagc
    18421 agaagtcgct tctctgaaat aaacgaggct tttttggata tccatgattt gataaagttg
    18481 tttgttttca gtggatactt gaagtttggc ttccaaagta tcgcattgag attgaagcgt
    18541 agctaaataa ctgttgtaag agagtgtgac ctgccaaatg aattgaaaga agatattgag
    18601 attaggcgaa atatcacttt ttggaaaggt ctggctaaag actttcttta aaaacagtgg
    18661 ttcatgattc gtaattgtga taagcttctt tttgggcgtc aaaataatag agagcgggta
    18721 tgtatccact tgaaaataac cgctaggact tgttttagca aaaggatatt gtaacaataa
    18781 taacgctggc tttgtcaact ttgattgatt gaattcttct gtacgggaat tttctgcatc
    18841 gtccaatatg gaagtgatgt aatctgacgg aatttcaaat tgatgtgtca gctgatgaat
    18901 ctcttcttga ttaggacgtt ctacacaata ccagatcgtt tggtcagttt cctttccggt
    18961 attacgcagt ttctcattat ctaatgtaaa atatttgatc atgattttcc tcctgttgcc
    19021 tgtttctttt attataacgg atagggaatt ggaatacatg gaatgtgttt gtaagatata
    19081 gaatataact gcataaattt aaataaaatg aaacagttgt gtaaagtata tacagtatac
    19141 ttgaagcaac gataaaaaag gagtttacgt tcatgggcac attcacacca cttatcttgt
    19201 tttggtatat ttacccggta atcgttttgt ttggttgcca atttcttgta aaattatttt
    19261 cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc gattcctttt ttgtggggcg
    19321 gtatgcatgc attgtctaga aatacaggga caatttctat cttaccgttt ttctttattt
    19381 ctgttttgct aatgggaatt tgtattgctg ttttccaagc atattattat gaagaaatta
    19441 tttatccgcg ttatttcaag atgacttggc gtttggtttt tctgttgaca atcgtcttgt
    19501 acgctgtctt gatcattgtg aacatacttt cttacctatg aaaaaaatag aaaagctgta
    19561 aaaagtcttt taaaaggctt tttgcagctt gatttttaaa aaaatgttta tgaataaaaa
    19621 aagttgttcc cggatttccc agaaaaggtg gtagaaagtg ggggattgtg gtagactaat
    19681 tttagttagt ggaggaatgg ggggctttca atgttgatgg gtgaattcca acataatatt
    19741 gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg aagaacttgg cgaaaagttt
    19801 gttctgacac gcggattgga tggctgtctt ttcggctatc cgatgagcga atgggaaaat
    19861 ctggaagcta aactgaacga aatgccgttg gctaaaaaag acgcacgtac ttttgtgcga
    19921 ttcttctatt cggctgccac tgaatgcgaa cttgataaac aaggacgaat caatataccc
    19981 agcacgttaa gaaattatgc agctttgaca aaaggttgcg tagtcatcgg tgtatctaac
    20041 cgaattgaaa tttgggatga gacacgatgg caagattttt ctgcagcagc agaagagaac
    20101 tttgacgaaa ttgctgaaag tatgattgat ttcggactat aagaatagga agaggctgac
    20161 taatgactga aacatttcaa cactatacag tcatgttgaa agaaacggta gatggattga
    20221 acatcaaacc ggatggcgtt tatgtagact gtacactcgg cggtgccgga catagtgaat
    20281 atttattaag ccaactaagt tctaaagggc atctgtatgc gtttgaccaa gatcaaaaag
    20341 caatcgatca cgccaagctg cgtttagctt cttatgtcga acaaggtatg gtcacattta
    20401 tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga gcatgtagat aaggtagacg
    20461 gcattttgta tgatctaggg gtttcctctc ctcagctaga tgaagcagaa cgtggattta
    20521 gttatcatca agatgcaccg ttggatatgc gcatggatca gtcagctcct ttatccgctt
    20581 atcacgtaat taatgaatat tcctaccatg aattagtaaa gattttcttc cgctatggcg
    20641 aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg agtacgaaaa acaaaaccaa
    20701 tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt catcccagct cccgcaagaa
    20761 gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt gcggattgca gtaaatgacg
    20821 aactcggtgc cgaagaggcc tctttagaac aggcaatccg gttattgaaa gtcaatggaa
    20881 gaatcagcgt aatcacattc cattcattgg aagacagaat tgtcaaaagt atgtttaaag
    20941 aatatagtac ggtacaagat ctaccaccgg gacttcctgt catacctgac gaattccaac
    21001 cagaactgaa agtcattact cgtaaaccaa tccttccttc agaggaagag ctaacagaaa
    21061 acaatcgatc acgcagtgca aagttacgta ttgcagaaaa aataagaatg aaagaggagt
    21121 agaatgatgg cagaattaaa gaaaatgcaa gattacgaat atgatttacc tgaattggtg
    21181 gatcagccgg aacaacaaat gcctgattct tcttcgaatc aagaaatcat tcttccacaa
    21241 tcaccggcaa aacgattaaa gcagatttct gctttggaaa aaattgctgt ggcaagcgtg
    21301 gcgattgcta ttgttgcttt atgtgtttta acagttatgc tgcgcacaaa tatcagcgga
    21361 gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg ataaaaagca agaaaaaacg
    21421 agtttagaac aagaaaaaaa cgaactttct cgtactgaac ggattaaaca aatcgcagaa
    21481 gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag tgaagtaaat gagtcttaaa
    21541 aataaaattc ggcggtttat ggaaaagaaa aatctaaatc cgatgaacaa tcgcaaaaaa
    21601 gtaggtatca ttttatttgc tacgagtatt ggattgttct ttttatttgc cgtccgtttc
    21661 tcgtatatcg ttattggagg tcatgttgct ggtacctcat tagctgaaaa aacaaaacag
    21721 ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa cgatttatga tcgtaacggt
    21781 gtggcgctcg cagaagatgc ctcctcttat tcaattaaag cgatactctc aaaaacatat
    21841 acctctgggg ataaaaaact gtatgttgaa gaaaagaatt ttgataaaat agcagaaatc
    21901 ctgcataaga atctttctat agacaaaaaa gatgcactga atattttaga ggacggcgca
    21961 aaaaaagagc tgtatcaagt tgaatttggt agctatggga aaaatatctc ccaagaaacc
    22021 aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg ctggtcttta ttttgtcgac
    22081 catcaggctc ggatgtatcc aaatggcgtc ttttcttctc attttattgg atacgcagtt
    22141 ccagacaaag atgagaatgg cttagttggt aaactaggtt tggagtctgc ttacaatgat
    22201 atcttgagcg gtaaagatgg taagattatt tatcaaaaag ataattttca aaatcctctg
    22261 ccaggtacag tggcagaaga agaaaaagct gtcgacggac aagatatcta cacgacttta
    22321 gacagcagac tacaaagtta tttagaaaca ctgatggatc aagtaaatga agaatatcag
    22381 ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg gagaaatctt ggcaatggga
    22441 caacgaccta ctttcaatcc tgaaacaatg gaaggattga ctggaaaaga tgctatctgg
    22501 cgtaatttct tggtacaaga tagttatgaa ccaggatcaa ccatgaaagt tttcactact
    22561 gcagctgcta tcgaagaagg agaattcaac gagaatgaaa ccttccaatc tggaaaaatc
    22621 caagtagaag atgctacgat caatgaccat gactttggtg aaaaaggtgt gctgaccatg
    22681 cgtcaagctc tttcatggtc aagtaacgtc gggatggtca tactggaaca gcgattaggc
    22741 ggacgatggt ataactattt acaaaaactg ggatttggac aaagtactca ttctggatta
    22801 gatgatgaag taaacggtgc tttacctaca ttaaatattg tcgaccgagc aatgagtgct
    22861 tatggacaag cggtaggtgt gacgaatttc caaatgatga aagctttcac ttctattgcg
    22921 aataacggta caatgattca acctcgatat atcagcaaag tggtggatcc ccaaactgga
    22981 gaagagcgaa caactcaaac agaagttcta gggcaacctt tttcaaaaga aacaacagaa
    23041 aaagtccgtg aatatatgag agatgttgtc gaaagcgaaa actacggtat tgcttatggt
    23101 gtatatagtg tacctggata caatgtatcg gcaaaaaccg gaacagccca aatcgcttct
    23161 gatacagggg gatatcaaac aggagataca gcctacctgt attcgattgt ggagatggtt
    23221 ccttctgaag atccagacta tgtcttgtat ctaacaatga aacaccctaa gacatatgat
    23281 cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac gggcaatgga ttttaaagaa
    23341 actgaagaag attcagatac agaaacaaaa acagaaaaag tatccgtagc cgattatcgt
    23401 aatcttgaag cggacgttgc agcagctgat gctcaaaaaa gtggactgca acctgtagtg
    23461 atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca acggtgatca gttgatctct
    23521 ggagaaaaac tgatcctata tactggtggt gataagctga tgcctgacgt aacaggatgg
    23581 tcaaaagcag atatcatgaa gctggggaaa atcctcggta ttgaagttag ttttgatgga
    23641 gatggttatt gtgtcaaaca agaacttgct ccatatgaaa aaatcactga agacaaactt
    23701 agttttactt tagaagaata agaagagaaa taggagagaa aagagcatgg aatggacaca
    23761 agcattgatt cccattgtca gcagttgtgc aatgacaatt gccgcaatgc cgctatttat
    23821 tggttatttt caaatgaaaa agcaaggtca ggcgattcgt gaggagggac caaagtggca
    23881 caatagcaaa gccggaactc ctacaatggg cggcttagtg tttctgatcg gctctatttt
    23941 gacaggaatt tgggttggag cttggcaaaa acagctaact cctactcttt tcatcttgct
    24001 ttttgtatta gcgttatacg gagtaatcgg ctttcttgat gattttataa aaatattcaa
    24061 gaaaagaaac atgggactga actcgaagca gaaattgatt ggacagattc tagggggaat
    24121 catcttttat cttgtttacc gttctgaagg ttatccaggt gtattgaatt tcttcggact
    24181 agatctacct ttaggaatca tttatggtat tttcgctctc ttctggcttg ttggattttc
    24241 aaatgcagta aatctgacag atggcatcga tggattagtt gctggcttag gaagtatctc
    24301 ttttgcagct tacggtctaa ttgcttggca tcagcatcag tatgatgtat taatcatttg
    24361 cttaagtgtt ttaggaggtt tactgggttt cttcgtctac aacagaaaac ctgccaagat
    24421 ttttatggga gatgtcggtt cattagcgtt gggcggactt ttagcggcaa tttctataat
    24481 gctaaaccaa gaatggacat tgcttttgat tggtttgatc tatgttatgg aaacagcaag
    24541 tgtgatgctt caagttactt cctttaagct tacaggaaaa cgaattttta aaatgtctcc
    24601 aattcatcat cactttgaaa tgtgcggatg gtcggagtgg aagattgata cagttttttg
    24661 gttgatcagc attgtgactt cgttgatcac attatggatc gtttggtagg agatgacggg
    24721 aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct tgtcttagga ctcgcaaaaa
    24781 gcggagtaag tgcggccaaa ttattacatg aattgggcgc acttgtcacc gttaatgatg
    24841 gaaaaccttt tgacgaaaat ccggaagcac aagagctgct ttctttaggg ataaaagtaa
    24901 taacaggtag tcatccaatc gaattgttgg atgaagaatt ttcattgatg gtcaaaaatc
    24961 cagggattcc ctacagtcat cctttagtag caaaagccca agaaatgggt attccggtaa
    25021 ttacggaagt tgagctagct tacgaagtag cggaatgccc aattattggg attacaggaa
    25081 cgaacggaaa aacaacgaca acaacgatga caggactact actgaatgca ggagcagatc
    25141 aaggaattgc acgtttagcg ggtaatattg ggtatccagc aagtggtgta gcgcaagaag
    25201 caaaatcaga agataaaatt gtgatggaat tgtctagctt ccaactcatg ggaatcacag
    25261 atttccgccc tcatatagcg gtgattacca atatctatga agcacatatt gattatcatg
    25321 gtacaagaaa agaatatgtc aaagctaaat ggaaccttca aaaaaacatg acagaaaaag
    25381 attatctgat ccttaactgg aatcagtcag aactacaaga attagcgcaa agaacaaaag
    25441 cacgcgtact gcctttctcg acaaaagaag tgttggaaga cggtgtgtat gctgacgatt
    25501 actcaatata ctataaaaaa gaaaaaataa tggaaatatc tgaacttggc gtaccaggta
    25561 agcataatgt agaaaatgca ctagctgcta tttctgtagc aaaattgtat ggtatatcaa
    25621 atgaagctat acgagaaacg ttgcattttt tccatggcgt accacatcgt acgcaatatg
    25681 taggagaaat ccaaggcaga aaattttata atgattcaaa agcaaccaat attttagcga
    25741 ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt gttattggct ggcggattag
    25801 acagaggaaa tacatttgat gaattaattc cttcattaaa aggaatcaaa gcaatggtcg
    25861 tatttggcca aacaaaagaa aagttgatgg atgctggaaa aaaagcaggc atcgagacaa
    25921 tagtaacagc cgattctgta gaacaagcag ttcctttagc attagaaaac agtacagatg
    25981 gtgatgtagt tttattatca ccagcgaatg ccagctggga tcaataccca aattttgaaa
    26041 ctagaggaaa cagattcatg gaagctgtga accgattaaa atagaaaaag tagaagcgag
    26101 cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag ggggacatat ttatccagct
    26161 cttgcctttg tcaattatgt aaagactcaa gaaccgaatg ctgaattcat gtatgtggga
    26221 gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag gaatgccttt ccataccttg
    26281 gagattcaag gatttaaacg aaaaatttcc atgcataaca tcaagacggt ccgattgttt
    26341 cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt ttcaaccaga tatcgttatc
    26401 ggtactggag gatatgtttc cggagcggta gtgtacgctg cagccaaaat gggtattcca
    26461 acagttatcc atgaacaaaa cagtgtacca ggtgttacca ataaattttt aagccgatat
    26521 gtggatcgga tcgctctttc atttaaagat gcggcttcct tttttcctga aaacaaagca
    26581 gttcttgtag gtaatcctcg agcacaagaa gtagcagata ctaaaaaatc agatattttg
    26641 aaaacatttg atttggatcc agaaaagaaa acagtcttga tttttggcgg tagtcaagga
    26701 gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg aatatattcc ttcttcttac
    26761 caagttttgt atgcttcagg agatagatat tatgaagaga tcctaaataa aataaatcct
    26821 gaaatacaaa atattagtgt ccagccttat atcaaaaata tggcagaggt catggcttcc
    26881 agtgatctgc tggtggggcg tgctggtgca acttcgatcg cagaattcac agctctgggg
    26941 ttaccggcag tgttggttcc cagcccatat gttacgaatg atcatcagac taaaaatgca
    27001 atgagtcttg ttcacgcagg agcagcaaaa atgattgcag ataatgaact aacaggtgaa
    27061 tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag aattgcaaaa gcaaatgtgc
    27121 cgagcttcta aagaacaagg aatccctgat gcttcaaaac gtctttatga cttagtaaaa
    27181 caaataatca aaaaataaag gcggtggtct tagtgagtaa gaaaaaagaa ccaaaaaaat
    27241 tgtctcatcc gtcttctgat gaaaacaatt tgactccttg gcaaaaggct aaccgaaaat
    27301 atctggcaga acaagagatg aaaaaccaag agccaaaaaa agaagacata acattagata
    27361 cacccctttc agattctgaa gaagaaaaaa cggttcaaga ggaacagcaa gaagaaagcc
    27421 agtccgagaa aaaaatcgaa ttttttgaag agatcaagca aaagaaaaac ggtggaccat
    27481 ataacggttc ttttttgaac cggctgccca atttaaaaag tcaacggcac aaagtactat
    27541 ttcgtcggtt agctttgatc atcactgtat tgggtatacc gctgattttt ttgatctatt
    27601 atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc aggcaataag acagtcaaca
    27661 gccaagaaat catctctgat acaaaattgt cattaggaga aaatgtttgg ggacagtatt
    27721 ttcatcgatc tacttatatc gatcgcctta aaaaagcaca gccaagaatc gaaacagcaa
    27781 atatacattt caaagggatg aatgaattcg atttggatgt aacagaatat aaagagattg
    27841 ctttgatcgc aaaaaacaat caatactacc cagtgattga aaatggaaca gtattagatg
    27901 aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga agagttcaaa gactctgcaa
    27961 aaatcaaaga attaacaaag caatacaatc agttatcatc agaattacaa aaagcaattt
    28021 ctgaaatcaa gtacacgcca agagcaagca ataaaaatct gatccaattg aatatgaatg
    28081 acggcaatca agttattgta aatatcaata atcttgcgaa ccaaatgaaa tattattcgc
    28141 aagtagccaa agatatggat gaaaaaggtg tgatcgacat ggaagttggt atcttctcgc
    28201 atccttacgg tagcactcaa gaaacggaag aatcgggcca atcggaagaa acaactgaaa
    28261 gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga ggcagaaacg caaaaagcac
    28321 aaacacctgg atcgtctagc acaaacggat catctgattc aaatgattca agtgaaacaa
    28381 gtcaaataga agataatcca agtacaactc cgtcaagttt aaatgaaaat tgataaaaca
    28441 actttaaaaa gtaagaatgt actttctaaa aaccagtaat ttatggtaga attggaagca
    28501 gtgaatatat ctattaataa gtatatttta aaacggacgc tagttgttcg cttgtatatg
    28561 gaatagtaag taggagggaa tcccattcat ggcaaaaaca ggaatgtatg taggccttga
    28621 tattggaacg acatctgtta aagttgtcgt ggctgaatat atcgacagcc aaatgaatat
    28681 tattggagta ggaaacgcaa aatcagaagg gattaaccga ggcattatcg ttgatatcga
    28741 taaaacggtc caagcgatac aacgagcagt acgacaagca gaagaaaaag caggtatcca
    28801 gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt gaagtagaaa attgccaggg
    28861 aatgattgca gttaacggag attcaaagga aatcaccgat gaagatgtca gaaatgtggc
    28921 ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa atcgtgtcaa tattgccaca
    28981 agattttact gtcgatgggt tcgagggaat caaagatcct cgtggaatga tcggcgtaag
    29041 attagaaatg tacggtctgt tgtttacagg acctaaaacg atcatccata acatacgtaa
    29101 atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg attactcctt tagcgctgac
    29161 tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg atcgtcattg atatgggtgg
    29221 cggccaaaca acaacggctg ttatgcatga taagcaattg aagtttacca atcttgacca
    29281 agaaggtggc gaatttgtca ctaaagatat ctctattgta ttaaatacgt catttaacaa
    29341 tgcagaagcg ttgaaaataa actacgggga tgcataccca gaacggacat caccagatga
    29401 agaatttcca gtagatgtga ttggtcagtc agaaccagtg aaagtcgatg aacgctactt
    29461 gtcagaaatt atttcagctc gaatggaaca gattttcaac aaagcaaaag atgcattgga
    29521 ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg acaggcggag ctgctagtct
    29581 tcctggtgtt gtggacttgg cacaagaaat cttcggcgta aatgtaaaat tgtatgttcc
    29641 aaatcacatg gggctgagaa acccggtatt tacaaatgta ataagtatcg tggattattc
    29701 agcaaacttg agtgaagtgt atcaattggc aaaaattgct gttacgggtg aaacctcagc
    29761 agctcgtcaa atggtagttg aacaagaaac aacaaacaca tatgagagct atgaagcacc
    29821 tgaagaaaca atctacgatg agccggaacc aaaagagtcc ggagaaaatg taaaaaataa
    29881 aatcaagggt ttctttacaa atatttttga ttaattcatc ctgggaggaa taagatatgg
    29941 aattctcaat tgataataat atcaatgacg gcgcagtaat caaagtcatc ggagtcggtg
    30001 gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa cgttaaaggt gttgaattca
    30061 ttacagccaa cacagacgtg caagcattaa aaaattcaaa agctgaaaca gttatccaat
    30121 taggccccaa atatactcgt ggtttaggtg ctggttctca gccagaagtt ggacaaaaag
    30181 cggcagaaga aagtgaacaa tccttacgcg aagctttaga cggtgcagat atgattttca
    30241 tcactgcagg aatgggtgga ggaaccggta caggtgctgc accaatcgtt gcaggtatcg
    30301 cgaaagaatt gggcgcattg actgttggtg tcgtgacacg tccattcact tttgaaggac
    30361 cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt gaaagaaaat gtggatacat
    30421 tattaattat ctcaaataac cgtttattag aagttgtaga taaaaagaca ccgatgcttg
    30481 aagctttccg tgaagcagat aatgttttac gacaaggtgt acaaggtatc tctgatttga
    30541 tcacagcgcc aggttacgtt aaccttgact ttgctgacgt gaaaacagtg atggaaaacc
    30601 aaggtacagc attgatgggg atcggtgtgg ctagtggaga agatcgcgta gtagaagcaa
    30661 cgaaaaaagc aatctcctct ccattgcttg aaacatctat tgatggagct gaacaagtac
    30721 ttcttaacat cacaggcggt ttggatatga cattgttcga agcacaagat gcttcagata
    30781 tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct aggtacatct atcaatgaag
    30841 aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg tatcgatgaa tcaaaaaagg
    30901 aacgcaagtc tagccgacca gctagacaag cacaaatgca atcacctgct caaaagactg
    30961 tattagatat ggatcaagct aaaccaactt cttcagaaga agaaaacagt tttggcgatt
    31021 gggatatcag acgtgaacaa aatgttcgtc ctagagttga tgattccaat tttgacaata
    31081 tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac aaaatctcat ggcgatgatg
    31141 aattaaatac gccaccgttt ttccgtcgta aaaaataaag gagaggaaga gcacatgatt
    31201 gctgacaact tgcagaaaat caagcaagaa attcaggatt cgtgtgctct tgttcatcgt
    31261 gatccgaaag aagttacatt agtagctgta acaaaatctg ttgaatccgc tcaagctgaa
    31321 gaattggtta gagctggcgt tatgaattgt gcagaaaacc gagtagataa attattagaa
    31381 aagaaacaag atttatttga ttttcctgaa ataaagtggc atttaattgg taatttacag
    31441 cgcagaaagg taaaattgat tgtaaatgaa attgattact ttcatgcgtt ggacagttta
    31501 agattagcag aagaaatcca gaagcggtta gagaaagaat tatcctgttt tattgaagta
    31561 aatgtttctg gtgaggaatc aaaacatgga atttcaccag atgagctttt accgtttgtg
    31621 gaatctttag ctgcctgcac aaaaatcaag gttgttgggt tgatgactat ggcgcctaaa
    31681 gaagcttctg atgagcaaat ccataaagtg tttggtacgc tgaaagaatt gcgtgatctt
    31741 gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat taagtatggg gatgagtcaa
    31801 gactttcaaa ttgcgattga agaaggtgca acatttatcc gtgtaggaac agcgctattc
    31861 aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac agaggagcaa ttgctaattt
    31921 tttcggatta gctgatgagg aagagtacga ataccaagat tatcctgaaa caacaaaaaa
    31981 ggctgtacag ccaactaaaa aaaatacaac acagaatcaa tcaactcatt ctgtatctgc
    32041 tgcgaatact catgaaaaac aaaaaacggc gacttcacgt cctgtaacgc atgaaagtat
    32101 tcagccggct gaaaagaaaa aagtaattga actacatcaa tcacctacaa aaactgtagc
    32161 gaaagaaaga acagcttcaa gaacctctac acaacctaaa gcaaatcttg ctggaaaaat
    32221 cactgtaatg gaaccaagag cttattctga agctatggcg attgctaaac gaatcattgc
    32281 tggagaagca accttagtga attttcattt agtagaagaa aaacaagcga gaagaatcgt
    32341 tgattttcta acaggaacag tttatgcact agatggagat atcaaacgtg ttggagatga
    32401 gatttttctt tgtacaccga ctgggatgga gattgacagt tcaaccgctc aatcttttgc
    32461 agatgcgaat ttgtttgatc tgtaagagga ggaactacga tttatactat tgcactatta
    32521 cttcatttac ttcaacgggc agcctatttc tatagcatta tcttgatggt atatgcattg
    32581 ctctcttggt ttccaggcgg gtatcaatca gggctaggac gattattagc taagatctgc
    32641 gaaccgtata tcagtttgtt cgatcgtctg cctttgagga ttggaccctt ggatttcaca
    32701 attttagggg caatcctgat cttgaactta gccgtacaag gtttagcaca gatcgttata
    32761 tggataactg tccatttagt ttattgattg aagcaacaaa atctttattc tcagaataga
    32821 taggagggga aaattttgga tgcaaatgta taccagcact ttcgggcaga tgaacgtaca
    32881 tttatcgatt cggtaggcga ttggattgaa caggttcaag gacaatatgc accctatctg
    32941 accgaatttc ttgacccaag acaatcctat attttagaaa cactgattcg acaaagcagt
    33001 gatttgcgtt tcatgtttta tggcggatat gaacaggcag aaagaaaaag atgtttgatt
    33061 ttccccgatt attacgaacc tgtagaggaa gattttgaaa cagcattgta tgaaatccat
    33121 tatcctagca aatttgccag cctaagtcat gggaaaatcc ttggaacttt agtgggaacg
    33181 gggatcaaac gctcttactt tggcgatatc atctcggacg gtgatcgctg gcaagtattt
    33241 attgcaaatg aggtggatca ttttgttgct gcacaagtaa caaagattgg aaaggttgct
    33301 gtacgcttgg aaccaatcaa atacacagaa atgattatgc cgaaagatag ctggacacaa
    33361 gaaagaggaa cagttagttc catgcgacta gacagtgtga tctctgagat ttataatatt
    33421 tccagacagc ggtccaagca gctgatcgaa gctggtaaag taaaagtgaa ctggacagaa
    33481 aatacaagac ctgattttgt acttgaacta ttagatatta tttcagtcag aggttatggc
    33541 agagtccaga tccaagaact tgaggggaag acgaaaaaag aaaagtacag ggtactgttc
    33601 ggtgtattac gtaaataaaa taaaaaggtg gtttactcat ggctttaact ccattagata
    33661 tccaaaataa gacattcccg acaaaaatgc ggggatataa tcaagacgaa gtagatgatt
    33721 tcttagattt agttgttcgt gactatgagg aattgactca aagaaatcga gaattagaaa
    33781 aagcagtcaa acattctgaa gaaaaacttg agtacttcaa tgaattaaaa gatgctttga
    33841 accaatcaat catcgtagct caagatacgg ctgataaagt aaaaacaagt gcaagcaagg
    33901 aatccgaagt gatcgttact tctgcacaaa acaaagcaga tgagttagtt gcgaacgctg
    33961 aaaaacgtgc acatcaatta acaactgatg cagaagaaaa agcaagaaaa atcttgacag
    34021 atgcaacaga aaaagcaaga cagcttgcga cagaaactga agatcttaag aaaaaaacac
    34081 gagtattcca tcaacgtatc agcttgatgc ttgagtctca attagaacaa gtgaaaagtc
    34141 cggaatggga tgaaatttta caaccattct ccagctacgt gactgacagc catgaagtga
    34201 tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga tactgatgta aactcagaca
    34261 caggagtcat agaagcacct atgacggcat ttgatacaca ggctattgat atctcgatcg
    34321 tgcctggtga aaatgaaaac gagtagaaca gaaaagcact ttgttattct taaagcgagc
    34381 cgatgagagt ggaagttcgg taagacactg catggtgaaa gatcctctac ttgagacctg
    34441 cttttccgaa attagagtaa gaagcagcgg ctgacctcgt tattggtcac agagagtttg
    34501 cactagatag atgcaactaa atttgggtgg taccacggca tgttcgtccc ttgcggctga
    34561 acatgctttt ttgtgtccgg aaaacaaata aaggagtgta tggttgaatg aaaatgaaag
    34621 aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg taatttgcca aaccgagaag
    34681 gcgagtggca aaaagaatgg gaagaaaatc gaatctacca aaaaagacaa gagttgaacg
    34741 aaggaaaacc tagctttgtt cttcatgatg gacctccata tgccaatggt aatatccatt
    34801 taggacattc attgaataaa atcagtaaag acattatcat tcgttcaaaa tcaatgtctg
    34861 gctatcgtgc accatatgtt ccaggatggg atacacatgg attgccgatt gaacaagtat
    34921 tggctaataa aggcgtgaaa cgtaaagaaa tgtccatggc agaatacttg gaaaaatgtc
    34981 gtgaatatgc actttcccaa gtagataagc aacgagcaga tttcaaacgc ctaggagttg
    35041 caggagattg ggaacatcct tatgttacat tagatccttc ttatgaagct gcacaagtac
    35101 gcgtatttgg taaaatggct gaaaaaggct atatttacaa aggattgaaa ccaatttact
    35161 ggtctccgtc aagtgagtct tctttagcgg aagctgaaat tgaatataaa gatgtaaaat
    35221 ctccatctat ttttgtagct ttcaatgtca aagacggcaa agatattctt gatgaagata
    35281 cagcttttgt catttggacg acaacaccat ggacattgcc agcaaaccaa ggtattgctg
    35341 taaatccaaa atttacgtat gtattggtgg aagccgatgg ccgtaagttt gtcgtagcga
    35401 aagatttgct agaaacagtc caatcagaaa tcggttggga aaatgtaaca gttctaaaag
    35461 aatttgctgg acaagaaatg gaatatatga ctgcaagtca tccattctat gaacgtgaat
    35521 cacttgtgat tttaggcgat catgttactt tagacgctgg tactggatta gtccatactg
    35581 ctccaggaca tggggaagat gactatatcg ctggtagcaa atataaacta tctgtagtgt
    35641 cacctgtaga ctcaaaagga ttgtttacag aagaagcacc tggatttgaa ggtatctttt
    35701 atgacaaagc aaatcctatg atcactgatc tattaaaaga aaaaggagct ttgctgaagc
    35761 tagatttctt tactcatagt tatcctcacg attggcggac gaaaaagcct gtgatctatc
    35821 gggcaactcc acaatggttt gcatctatcg ataaattccg tcagaatatt ttggatgaag
    35881 tagaaaaagt agagtgggtt atcccatggg gtaaaacacg tttgtataat atgatccgtg
    35941 accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg agtaccactt ccgattttct
    36001 atgctgaaaa tggagaagca atcatcacac cagaaacaat cgaacatgtg gcaaaattat
    36061 ttgctgaaca tggatcaatt atctggtttg aaaaagaagc gaaagaactt cttcctgaag
    36121 gatttaccca cccaggttct cctaatggcg aatttacaaa agaaaaagat atcatggatg
    36181 tctggtttga ttctggttct tctcatgaag ctgttttacg tcagcgacca gaattatcat
    36241 tcccagcaga tatgtattta gaaggatcag accaatatcg tggctggttc aactcaagta
    36301 tcacgactag tgtggctatc aatggtgtag caccatacaa atcagttatt tctcaaggat
    36361 ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt aggaaacatc attgcaccag
    36421 aaaaagtgat caaacaattt ggtgcagata tccttcgctt atgggtatct agtgtagatt
    36481 atgaagcaga tgttcgtgtt tctatggata tcttaagtca agtggcagaa gtatatcgta
    36541 aaatcagaaa tacgatgcgt ttcttattag cgaatacaga agatttcgat cctaaaaaag
    36601 atactgtttc gtacaatgat ttacgttctg tagacaaata tatgaccgtt cgattgaacc
    36661 aagtaatcaa agaaatccga gaagaagggt acgacaaata taacttcatg catatttacc
    36721 gtacagttat gaacttcttg acggttgatc tatcgtcatt ctacctggat tttgctaaag
    36781 atgtagttta tattgaagca gaagatgatt atcaacgtcg ttgcatgcaa actgttttct
    36841 atcaaacagc tgtagctttg acaaaattat tgactcctat cattccgcat acagcagaag
    36901 aaatctggtc attcctgaaa gaagaagagg agtacgttca gttaagcgag tttcctggtt
    36961 atgaagagtt tgcaaaccaa gaagaattga tggatacctg gactgctttc atggacttcc
    37021 gtgataatgt cttaaaagca ttggaagaag caagaaacag caaattgatt ggtaaatctt
    37081 tggaagcaaa actaactgtt tatccaaaac aacaagttcg tgaaatgtta aaagctttgg
    37141 atgcagatat tgcacaatta ttgatcgttt caccagacta ctttgaagtt atggcagcag
    37201 atgaacaagt gccagataac gctatggtat ttgatgatgt tgctattaca gtggaaaaag
    37261 cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa agatgtagga gtagatgaaa
    37321 aacttcctca tctatgcggt cgttgtgcaa aaatcgttga agacttctat cctgaagctg
    37381 tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg tgtgacatgt tctttgtcac
    37441 accccctttt gttatcaatc gtttaatttt ccacgttcac gataccagtt atctggttgc
    37501 cagatccatt cgaatccgtc tttttcaagt agttcgaaag ctgctttagg tcccattgat
    37561 ccagctttgt agttgggaaa atccggttgt gtttggtccc aagcttttcg aatgacatcc
    37621 acgatatgcc aagattgagc gacttcttcc caatgagaga agttcgttcc atcaccattc
    37681 aacgcatcta atagtaattt ttcgtaagct tctgggctat tttcaaccat ttctgcacta
    37741 tttctaaatt ccaatttgat tggttccgtt tcaaatcctt gccctacttc tttcccattc
    37801 aaggataaag aaaatccttc agttggctga atatagatcg ttagaacatt aggtggaagt
    37861 gtcgtatcgt cacatggttc atcgacagat gttttgaata cattaacagg aacttgtttg
    37921 aatacgatgt tgatccgagt ccctttttca gtcaaacgtt tgcctgtacg tacatagaaa
    37981 ggaacacctg accaacggaa gttatcgata gtgaatttgc ctgcgacgaa tgtttcagtc
    38041 tctgattgag catccacttt gtcttcttcg cgatagccct tgaattgtac accatccaat
    38101 tcaccttgag catattgccc gcgaacgaag ttttctaaca cttcttcttc gttataaatg
    38161 cggatagctt tcaatgcttt gatcttttct gtacggattt ctttttcgga aaatgctact
    38221 ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat gattttgcac catgtcttta
    38281 agtgcgccac tatgatcgta gtagcccccg cgatcttcta caccgaggtt ttcgccaaaa
    38341 gtaatttgga tattgtcgat atagcgattg ttccattgag cctcaaaaat attattggca
    38401 aaacggatag ctgagatgtt ttggatcatt tcttttccta aataatgatc aatcctgaaa
    38461 atatcttgtt ctgggaatac ttctctgatt tgctggttca attcaaaagc agactggtaa
    38521 tcagaaccga acggtttttc tatgatcaaa cgattgaagc cattttttgt cataatattt
    38581 tgtgatttca aatgagaaac gatcgttcca aaaaattgag gtgccatagc caaataatag
    38641 acacggttac cgtttaattg atagtgtcca tctaatcggt cagacaattc ttttaatgtc
    38701 tgataatgcg ttgaatcatt tacatcatgg gattgatagt aaaaatggct tgcaaaggta
    38761 gttgcttctt catctgaagg attcaatgca cggattgttt ctttgacaac ttcacggtag
    38821 tgctcatcgc tccagggacg gcgagcggtt ccgattacag caaaatgctc gcctaaattt
    38881 ccttttctgt aaaggcggaa caaagacggg tacaatttac gctgggctag gtcacctgta
    38941 ccgccgaata tcgtaaacaa tacatttttt tcattagaca tgtggataca ctcctttata
    39001 ttttatcgac aaaaatcgtg ctggccgcct taaagctgac ggggattttc tttctatcat
    39061 tttggatagt gatcggtcct tcataagctg cgatgtcaac gatctcatat tcttcgttga
    39121 tattcaggtc aatagtgact aagtaatcca acaattcttt ttcatcaagc actcgtgcga
    39181 tacgcacttt tgtaccgaca ggataggact ccaatgtttg tcggcgttct tcatggacaa
    39241 cttcctcttt tttaggaatc gatcctccat gaggacaatg ttcaggatga ttcaaatagt
    39301 tttctaaatg atctgcaaga tgttccgaag tcacatgttc caatacttca gcatcatcat
    39361 ggacttcatt ccagctatag tctaaatgtt caactaaaaa aacttcccat aagcgatgtt
    39421 tgcgaatcag actgctagct ttttgcagtc cgcttgcagt caattgtaca ccttgataag
    39481 gggaatgttc tacaagctct tctttcacaa gtttagaaat catttcactg acagatgcag
    39541 ctgagacatc tagactagat acgatttgtt tattgttgac tttcgttgta tctccaccta
    39601 gttctaaaat gattttcaaa taatcttctc gatttggtgt catattcgat catcctttca
    39661 tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg ttaattgact atttttctaa
    39721 ataaaaaaca aaggattttt agacgttttt acaacaaaaa acgaaagatg atagagaaga
    39781 ctcattcttt cgtttataaa ggatatatat atacattggg agggatctat ttttcagata
    39841 acaacttata tgaagtgtct gcagattcgt cataaagagt ttgttcggga taagaaaaga
    39901 taagataaaa accatactga tcacgtacga ctaaacgata ttcatctatt tctaccacag
    39961 atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc agatgtaatc tgtaattgtt
    40021 gtttttgctg gctatcacta aagaaccatg taccttgata ctttgagagt ccttctgact
    40081 tttccgcttg ttttttcttt ttcaagtaaa taaaacttga gagaacggta atgagtgaac
    40141 caagaaaata gatcattttt tttatcacca aatcactcct ttatgagaaa ataatcgcat
    40201 agacatattc tttcttcttt atttcattgt accgaataaa agctaaaatt tctctaagac
    40261 tttcgactgg tttttttact gtttttctac aaattatgat aggatacata gtaggaagaa
    40321 aggtgacata atttgaagta tcagcaagtg gaaatagctt tttttattga ccgcccgaat
    40381 cggtttatag cacattgtat gaaaaaagac ggagaaataa ttattgcgca tgtcaaaaat
    40441 acaggtagag gaaaagaggt cctgatacca ggcgctgaag tggctattgt atttgctcct
    40501 ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa aaaagaaggg tgactggttt
    40561 aatatcgata gtcaattgcc taatcggctg gcaattgatg gtattttaga cggcacgatc
    40621 cttttaccag gattaactgg tccatttacg gtatacaagc gtgaagtaac ttatcttcac
    40681 tccaaatttg atatttattt agagacggtg gtcggacaaa aagcatttgt tgaagtcaaa
    40741 ggtatgacac ttgaaaataa agcgattggt gcttttcctg atgcgcccac actcagagga
    40801 ttgaaacata taggagaatt aacgtatgcc gcacaagatg gttatgccgc ttatgtcttg
    40861 tttattgctc agttcgaaca tcttcatctg gcaacgatcc atgaagaaat gcaaccagca
    40921 ctagctgata tggttcgaca tgcgcagcaa agcggagttc aaatcctcgc ctataattgt
    40981 caagtatcgg cagatgaggt aactgtcaag caggccattc catttgatgt agatatccct
    41041 tttgaagatc ctatacaata gaaagaaggt aaaataatga tcaacttagg tattatcgga
    41101 acaaattgga ttactcatca atttgtccaa gcagctttaa gcacaaaaaa atatgaattg
    41161 acagcggtat attctagaca tttggaaaaa gcacaggaat ttggttctca ttatgaaggg
    41221 gatatcgaat tcgcaacaga tttgaagact tttttcaata ttactcatat ggacaccatt
    41281 tatattgctt ctccgaatag tcttcacttt agtcaagcta agcaagcaat tttggcagga
    41341 aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa aagaaatgga tgaaatcatc
    41401 catttggcaa atgaacacaa tgtgtatttt tttgaagcag caagaaatat ccatgaatca
    41461 ggttttaaaa agattgccga ttacttacca ttaaaagacg agataatcgg tgcaaatttc
    41521 agctatatga aatattcttc gcgctatgac caagtattag atggagaaga accgaatatc
    41581 ttctcgactc atttctcagg tggtgcattg atggatttag gtgtttacct tgtatatgca
    41641 gctgttgctt ggtttggaat gccaaaagaa gtccattatt tcccaagaaa gatttctact
    41701 ggtgtagatg gtcttggatg ggggatctta cgttatgaga attttgatgt atcgatccag
    41761 ccaggtaaaa tcggtgattc ttatttaccg tcagagattt attttgactc aggaacgcta
    41821 gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc atgatcgcgc gcataaagaa
    41881 atcattgatt tggcggtaac agctgcagaa aatccaatgg cagatgaagc agaggatttt
    41941 gccaatgtca tggctcatcc gaaagatcca gcttggggat tgttgtatga agagtggatc
    42001 gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa gaaaaaatgg cggcatcaaa
    42061 ttcgatgcag ataatgagga agatttttaa tgaacgaatt tgtacaagta tttcccgaaa
    42121 attggcagaa aaaatatgag gataaagggt ttatctcacc ttctcttatt caacgagcag
    42181 tttttcagcc actaagtaat aaacaaagta tagtagcggt ttctcctaca ggttcaggta
    42241 aaacactggc ttatctttgg cctctactac taaacgtgga accaggtgaa gcaagtgcgt
    42301 tggtcatttt tgcttcttct caagaactag ctattcaagt agcagatgtt gcacgtgaat
    42361 ggggaaaaga caaagagttg aaagtccaat ctttggtggg cggagccaac gtcaaacgtc
    42421 agattgaggg tttgaaggaa aaaccagaaa tcttgattgg tacaccagga agaatattgg
    42481 aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa aacaatggta tttgatgaag
    42541 cagaccagct atttgacgct gggaacagcc aaatcattga tcaaattctt catcaagctc
    42601 caacagagta tcagctagct tttttttcag cgacagcaga tcgttccctt gaaagcattg
    42661 aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac agcagaggac gattctcgaa
    42721 aaggactgag acattacttt ttacgtgtac cgatacgaaa gaaagatgac tacttgagac
    42781 gtctcacgca tatagaagat tttcatggtc tgattttctt taatcaactg actgaattag
    42841 gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt aggaagtctg gcctctgatc
    42901 agaacaagct actccgaaaa gcagcgctag aacaattcaa aaagaaaatg gtcagagcac
    42961 ttttgaccac agatgtggcg gctagaggtt tagatattac aggtcttcct tatgtagtga
    43021 atgcagaagt tccgttaagt gaagaagctt atttgcatcg ttcgggaaga actggtcgaa
    43081 tgggtaatga aggaatagta attacactcg tacaagataa taatctaaga gatttaaaac
    43141 ggcttttacg tccatcaaat ataacacttg aagagatttt tttatacgga ggtaagctgc
    43201 aaactgagca gccaaccaaa gaagatgcag ctcctgcagt aaataaaaag tatgcgaaaa
    43261 ctttttctgg aaaggagcag aacccagaat ataacaaaga aaaaataaga aaaaaagtta
    43321 aaaataaatc aaaaaaagag agaaataaag gagcaaggcg caaataagcg cctttttatg
    43381 ctatgattat gaaaacggga acaaaattgg ttgccagagg aggggttatg tgaaagaacg
    43441 tcaagaagag atcttgcagc tattgacaga aaaccaacaa ggattgacag caagtgatgt
    43501 agctgagcgc ttaactatcg atcgaagcaa tgcaagccga tatttaagtg aactatacaa
    43561 ggcccatcat attgtaaaaa ccgctggccg accagtcgtt tactctttgc caacggaaaa
    43621 gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa gtgacttttg aaacactcgt
    43681 tggagaaaat gattctttaa aagtcagcat acagcaggca aaagctgcga ttctttatcc
    43741 accgcggggg ttgcatacga ttatttttgg agaaactggt acagggaagt cgatgtttgc
    43801 tgaatgtatg tatcattttg caatcgattc agagatgctt tctgcagatg cgccatttgt
    43861 ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg ctctttggac acatctttgg
    43921 gatcaaaaaa ggggcttaca caggagcagc tcaagatagt cccggtctaa tagccaaagc
    43981 agacggcggt atattgtttt tagatgagat ccaccgttta ccgccggaag ggcaggaaat
    44041 gctgtttact ttcattgata aaggtattta ccgtccgctt ggagaaagtg cacaagtaca
    44101 tgaagcatct gttcagatca ttggggcgac gactgaatct tcagaaagtt tcttatctac
    44161 gttcaatcga cggattccta tggcaatcac cttgccgaat cttgcttcac gttcactgga
    44221 tgagcgttat gaaatcatct ctctttttat caaacaagaa gcgaatcgtt tgaatcaacg
    44281 tatcgatatc gaaaaagaag cgattcttgc cttcatgctt tatgatgcgg aaggaaatat
    44341 cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa tcttttttac attaccgtac
    44401 tcatcatgag aaaaagctaa tcattcgaaa agaagaactt tcccttcaag tacaaaaagg
    44461 attactgaaa atcaaggaaa taccggaacg tctcgaccga ttcatggaca gcaaaagtca
    44521 gtatttgaca tttgaaccag gatttgctga tgttgtctgg tcacaagatc cagaacgaaa
    44581 catgcaggtc tataacgata ttgaggaaaa agtcacttct ctttccgaaa ccggtgtgga
    44641 gaacattgat ctagagaccc tcatttcaaa agatgtggat gcttatttcc agacatatgt
    44701 caaagaattg actaaaagtt cgattcccaa agatcttttg ccagatgaaa tctggcggtt
    44761 aaccaatcaa ttgtatgatg tggctgaaaa acggttagac cgtatttata atgaaaaagc
    44821 tcgttttgct tttgctttgc atctgcaaag tacattggat cgtgtgagag aaggtcatat
    44881 gatcgtccac ccagatttga ataacgtacg gaaaaatttt aagagggaat tccaggtagc
    44941 aatcgatctt tcaacgatca ttgaagaaga agaacaagtt gagattcctt ttgatgaaat
    45001 cggctttatt agtatgtttc tttctatcaa tctaggagaa agtgagcctg ttaaagaaaa
    45061 caaagtagat gttctcatat tgatgcacgg cagacagact gcttcaagca tgttggagat
    45121 ggcacaagaa ctattaggaa caaaagtagg gaaagctttt aatatgccac tggttatgga
    45181 agttcaaaca atgtatgaag aagtgttaca atatgtcaaa aactatcaag agcatttgac
    45241 gaatggccta ctcttgttaa cagatatggg atcattaaac accttcagtg atttgattta
    45301 tgaagagact ggcattcgga cgaaagctat cacgatgaca agtaccatga ttgtgataga
    45361 agcgatacgg atggcaagtg ttggaagaag cttagaagat atttatcaaa atatccagct
    45421 ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa aagtctgaaa ctttacagcg
    45481 taaaaaagcc gtaatcgtga catgctttac tggtgaagga gtagctgcca aattatatca
    45541 gcgtattatg ccagtgatta atcaaaataa ggtagaactg atccagatgc agtttttaga
    45601 acgtgaatca ttcaaaaaac acatcgatgc cttattggaa gaatatgaga tcaaagcaat
    45661 tgcgggaaca gttgatgttg attatcaaaa tatcccattt ttttcagcct atgacgtttt
    45721 tgatgatgaa aaactaaata ttttaaagcg tatagctgat gatgagatcc cgacagctaa
    45781 aattgtcgat tcacttgctg gatcattaag cgatgtcttt tctattgatg aactgatccg
    45841 ttcattgcaa aagacagttc agcagatcca gaccgatttg tcgattatcg tggaacctgg
    45901 agtagatact ggaatcgtta tccatttagc cttcatgtta gacggattga tcaaacaaga
    45961 aagccatcgg caatttgaga aactgtctat tttctcaaaa atttatcgtt tggaaatgga
    46021 tatcgttcgg gcaaacttga tggcactaga acgaaaatat caggtaaaaa ttccagaaga
    46081 tgatatcgca tttcttacac aaatgtttct tgaaaataaa ataaaaaaat gaacacacta
    46141 atcatactgt ttacacacta aacatctgtg tgcgcactat aaaaaagagc taaaaagcat
    46201 gaaaacgcta tttcagctct tttttttatt ggcatgcttc ttgcgttata taaaagtgta
    46261 aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat catgttagtt tgttcagcag
    46321 ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc agcagaagaa aaagggatgg
    46381 aagccgatat ttttgcggtc tctgcctcag atgcagataa taatttagaa tctaagaatg
    46441 tcgatgtatt attattaggt cctcaagtac gtttcatgaa agctcaattt gaacaaaaac
    46501 ttgcgcctaa aggtattcca ttagatgtca tcaatatgca agactatggc atgatgaacg
    46561 gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata aatcaagtat gcagttgggg
    46621 gtataacaac gtggaagatc aacaaaatct agaagccatc atggggttaa tcatgtttgg
    46681 cggtaatgca aagagcgatg caatggaagc gattgcggct gctaaaatcg gtgattttga
    46741 gttagcggat aggaaaatcg ctgatgcaga agaatcactt atacaagcgc atcatgcaca
    46801 aacagacatg ttgacacaag aagcacaagg aaatcatatg caagtgacat tattgactgt
    46861 tcacagtcaa gatcacttaa tgacatctat tgcgtttact gatttagcaa aagaaatcat
    46921 cgaactttat cgtcgcgtat acagcgaata aatacaactt cttttttgaa cggaagaaga
    46981 aaaatttttg aacggatttt ttattttgtt ataaggagaa ctctctttat ataaaaaact
    47041 tataggagga agtaaaaaat gaacggacta tcaagttgga tggagaaata catcctgccg
    47101 gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt tgcgtgatgc ttttatcggc
    47161 acactgcccg caacaatggc gggatcagtc gctgtaatga tcaatgcaat tattcgtgat
    47221 ttaccgcaac agtttaacag tacctatgct gacagtttag cagcagacaa aggaatcttt
    47281 gccgtattga atgtcatcat cggaatcaat ggttttgtct ggaacggtac actagcaatc
    47341 gccggattga tctttgcctt ttcttggggg tataatcttg cccgagctta tggagtaaat
    47401 gatctagctg gggggatcgt tggtttagct accttgattc aaggtatttc ctttggtcca
    47461 gcattatcag cagcattaga tgtgaatgtt ccttcaaatg tcgcagatgc aatcaatagt
    47521 tctgagattg gtgcaacgat tgcagatggc acactgtcag ttggattatg gggttggcta
    47581 aaactagatc atttgaatgg aaacgcttat tttacagtta tgatcatggg agctatttca
    47641 gtcattattt tttgtaaatt gatgcttgcc aacattacga tcaaaatgcc tgattcagta
    47701 ccaccagcag tatctaaagc atttgcagcc attttaccag cgacgatcgc tttatacgtc
    47761 attgctatta tcaattatat cgtaggtcgt gtagctgatg ggcaactgat cattgatttg
    47821 gtgcaaaaat atattgcaga accattccta ggattatctc aagggttggg agcagtattg
    47881 atcgtcacag tatttgttca agtattctgg ttctttggta ttcatggacc aaatgtattg
    47941 gcaccagtgc tagagggaat ctggggacaa gcacaactaa tcaatattga tattttccaa
    48001 aaaggttata acggaaaaac tggtacacca gccgtgttag atgcaatcga agatggaaaa
    48061 gcttatatgt gggtccgcgg atcgttcgat gcttttgcat ggtttggcgg atcaggcgga
    48121 acgatcgtct tactgatagc tatcttgatt ttctctaaac gtgcagatta tctaacagta
    48181 gctaaattat ccattgggcc tggtatcttc aatatcaacg aaccagtgat gtttggtctg
    48241 ccaatcgtat tgaatgcaat catgtttatc ccattcttga ttgctccagt agtagcaaca
    48301 gcaattggat ggacagctac ttatcttggc ctagtcgctc cggtatcgca gcaagtcaca
    48361 tgggtagtac cgccgttctt attgtcattc ttagcaacag gagcggattg gcgggcaccg
    48421 atcgtaacat tagtatgtat ggtcgtgact ttcttgattt gggcaccatt tgtcatctct
    48481 gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag atgaacgtga ggagcgggac
    48541 gctttaagtt tcgttcctca taatgaattt tcgaggagga actgaaatga ttacaattgc
    48601 cagtgcaatg caacaagatg aaatcaaaga attgttagaa ggatacaatg aagaaggaat
    48661 gacttttaca tttaaagaaa aacaaggaat caagctgttc tttgaaacaa gtgcagaaga
    48721 tccggaagtt gcggctaaaa aagcaaagga actaatcaaa gcacagcctt ggggaacagt
    48781 cctttatttt caatcaacag ctgtttagaa aatggtttaa aaagatagga tggttgagat
    48841 gataaaaaac ggtttatttt tatgtagtat tggttctttg atcgtgttgt atagtttgaa
    48901 tccacattcg caaaggtatg atttgtatag tatggtcaca ggtctttttc taacaggatt
    48961 aggaatctat ttcttcatga aggggaaaaa aagagaagaa gcaaaggaga aaaataacta
    49021 atggaaatca cgaaaaaatt aaatattcca gcatcgtttt tttacgataa agttatggac
    49081 tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag taactagaaa acagctgaaa
    49141 aatttggagt acgtcaaaca attctcgcaa aataaccggg ctcgcataaa aatcgaagaa
    49201 gtcattgaaa accagtctta taagtttcgt acatcgacaa cgaagaatga attcgtcgtt
    49261 cattatcaaa tcaaaccatt ggacgattcg acctgtgagg ttcattacac agaaaaaatg
    49321 gagtcttatg gcatgcttca aaagttgaat gatatgcttt taggaacaat cttgatgtat
    49381 tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg aagcaacgta ttaaatcaat
    49441 gaaacatggt actatttagt tattgaaaaa tgaagtaagc tagaaggaat ttttcatagg
    49501 aagatagatc tttcctgcga atcctcacta gcttttttgt aggaaggggc agcaaaatga
    49561 caaacaaagt aagagagcta ggtgtatctt cgattgagga aatgtttgat ttagccactt
    49621 atgcatttaa tggggcagat acacctgaaa ggcgagaacg ttttcgtaca cttgcggaga
    49681 attcttggaa ttacggattt tttgatgagg aggatcggct aacaagtcaa gtcatggcga
    49741 ccccttttcc agtgaatttt tacggacaag agtacctaat ggccggcatt ggctatgttg
    49801 cttcttatcc agaagcaagg ggacaaggcg ggatcaatca gatcatggaa aagatccttg
    49861 aagattgccg tgatcgtaaa gtaagcttat cttatctggc gccattctcc tatcccttct
    49921 atcggcgcta tggctatgaa caatcatttg ataaaatcag ttatcaacta aacagtcgtg
    49981 atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg tatggatttt gaagatgcaa
    50041 aagctgcaat cagaagaatt tatgaacaga tgccggaaaa ccaacgagct ggtctgaagc
    50101 gcgaagactg gtggtatacg tataaattca agcaaaaagg caattaccag tttgctttgc
    50161 attttgatga taatgaggaa gcaacgggat atatcgttta tcagcttgca acgtcttcct
    50221 ttattattgc ggagtgggga tttttggatc atgatgcttt ttgcagcctt gttcgcttcg
    50281 taagttctca caatggtgct tttgaaacat ttgaatattc atgcggctac ggcggtaatg
    50341 atcaaaatta tctattagaa aatccatttg cttctgtaat gatcacacct tatatgatgg
    50401 cgaggatcgt agatatttct ttgtttttgg aaaattatcc atttaaaaag agacaagctg
    50461 catttgccct acaaatagaa gaagatcatt atgcgaaatg gaatgaagga atcgtggaag
    50521 taacaatcga aaatggaaaa aatcatctct caaaagtaga acaaacaaaa ctcccaatcg
    50581 ttcgaggaag tatccaacat atcacgcagc tattattagg gtatcgtaaa gtggaagagt
    50641 tggtattcca agaaagaata caggtgacaa aagaatatga agaaacgtta agctcaatct
    50701 tgccacagca acagccaatt cttaatgact atttttgata aaaaacgggt gatgacaata
    50761 tttttgtcac cacccttttg tttttcattt ggcatttgaa ggaaaatgtt aaagtaaatc
    50821 ctcttttttc gtaaatttga attttttgtt ttcttttgtt ttagggtttt cttttttgtg
    50881 gtcttggatt gcttctttcg taatcttttc ccgatttttt ttagatgaat ctaagcgttc
    50941 tgcgtatact ttttcttttg gcttatcatt cattggaaag gacctcccta cattatttca
    51001 ttctacctct agtttatcat ctgttaagga ctagtggaaa cgttttgcct aacttataag
    51061 ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa caagctacaa ttgatttatt
    51121 gaaattgttc ctgtagctca gtaggataga gcaatcgcct cctaagcgat aggtcgctgg
    51181 ttcaattcca gtcaggaacg tacaaataac ccctgtatcc tttgtgatac aggggtttgt
    51241 tttgtgtttg tgccaaaaat gtgccaaact agttatcatt tttatataaa ctatcgaaca
    51301 cagcattgat tttttcttta tcctgatctt caagctctcg aacaatatga agataagtag
    51361 acattgtagt ttctaaactg ctatgtccta aacgtttcga tacgctaagt atatttactc
    51421 cttgataaag taaaatagat gcatgtgtat gccttagtcc atgcaaagta aattgctttt
    51481 caatccctaa ttcttttaat tttttgcgca aatatttgct gacggcgttt gatgaaacta
    51541 atccattttt taagttgaaa aaaacaaaat tatgagggtt tttaacttca aaattctcga
    51601 ataattcttt ttgattgatt ttaaactttt ttaagagatc aatcgtatgt ttatcaatgg
    51661 aaattttcct atttgaagtt tcgttttttg tttttcccca ttcatttaat ttataattcc
    51721 atgttttatt aatagtgatg atttgatctt cgaaatcgat atcttcccat gttaatccta
    51781 gaagttcagc aaatcgcatt ccagtagcac cagcaactaa cacgagcata ggagaagagt
    51841 actgcgcaga aaggttttct tctacgagtt tcattaaaga tttaaattga tcataatcta
    51901 aatatttatc ttcttttggc ttcaatgaat cttttccttt gattactgct tttctagttg
    51961 gatcaaacgg aattaatcct tcttctacgg catctttcaa cgatgctcta atatg
//
LOCUS       DAIGUC010000017        48706 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.017, whole genome shotgun sequence.
ACCESSION   DAIGUC010000017 DAIGUC010000000
VERSION     DAIGUC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.017"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            23..646
                     /locus_tag="NOB46_001004"
     CDS             23..646
                     /locus_tag="NOB46_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057963.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="NOB46_001005"
     CDS             1096..2145
                     /locus_tag="NOB46_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1057964.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="NOB46_001006"
     CDS             2142..3023
                     /locus_tag="NOB46_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057965.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="NOB46_001007"
     CDS             3026..3796
                     /locus_tag="NOB46_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1057966.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="NOB46_001008"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="NOB46_001008"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCI1057967.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNGTDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="NOB46_001009"
     CDS             5107..6270
                     /locus_tag="NOB46_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI1057968.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="NOB46_001010"
     CDS             6387..6797
                     /locus_tag="NOB46_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1057969.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="NOB46_001011"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="NOB46_001011"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI1057970.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="NOB46_001012"
     CDS             9370..9654
                     /locus_tag="NOB46_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1057971.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="NOB46_001013"
     CDS             9814..10050
                     /locus_tag="NOB46_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1057972.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="NOB46_001014"
     CDS             10047..10445
                     /locus_tag="NOB46_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI1057973.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="NOB46_001015"
     CDS             complement(11112..12056)
                     /locus_tag="NOB46_001015"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI1057974.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="NOB46_001016"
     CDS             complement(12352..13296)
                     /locus_tag="NOB46_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057975.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="NOB46_001017"
     CDS             13517..14731
                     /locus_tag="NOB46_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1057976.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="NOB46_001018"
     CDS             14753..16768
                     /locus_tag="NOB46_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HCI1057977.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="NOB46_001019"
     CDS             complement(16851..18224)
                     /locus_tag="NOB46_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI1057978.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="NOB46_001020"
     CDS             complement(18250..18534)
                     /locus_tag="NOB46_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1057979.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="NOB46_001021"
     CDS             complement(18536..20551)
                     /locus_tag="NOB46_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI1057980.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="NOB46_001022"
     CDS             complement(20730..21035)
                     /locus_tag="NOB46_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HCI1057981.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="NOB46_001023"
     CDS             complement(21124..22155)
                     /locus_tag="NOB46_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1057982.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="NOB46_001024"
     CDS             22362..23237
                     /locus_tag="NOB46_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1057983.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="NOB46_001025"
     CDS             complement(23389..24231)
                     /locus_tag="NOB46_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1057984.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="NOB46_001026"
     CDS             complement(24323..26200)
                     /locus_tag="NOB46_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI1057985.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVCNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="NOB46_001027"
     CDS             complement(26197..27618)
                     /locus_tag="NOB46_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI1057986.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="NOB46_001028"
     CDS             complement(27621..31010)
                     /locus_tag="NOB46_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI1057987.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="NOB46_001029"
     CDS             31267..32658
                     /locus_tag="NOB46_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1057988.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="NOB46_001030"
     CDS             complement(32731..33378)
                     /locus_tag="NOB46_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI1057989.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="NOB46_001031"
     CDS             complement(33386..34072)
                     /locus_tag="NOB46_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1057990.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="NOB46_001032"
     CDS             complement(34078..35151)
                     /locus_tag="NOB46_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1057991.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="NOB46_001033"
     CDS             35373..36047
                     /locus_tag="NOB46_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1057992.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="NOB46_001034"
     CDS             36052..37392
                     /locus_tag="NOB46_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1057993.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="NOB46_001035"
     CDS             complement(37541..38527)
                     /locus_tag="NOB46_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HCI1057994.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="NOB46_001036"
     CDS             39251..40282
                     /locus_tag="NOB46_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1057995.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..41923
                     /locus_tag="NOB46_001037"
     CDS             40391..41923
                     /locus_tag="NOB46_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCI1057996.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            42062..42874
                     /locus_tag="NOB46_001038"
     CDS             42062..42874
                     /locus_tag="NOB46_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HCI1057997.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            42864..43349
                     /locus_tag="NOB46_001039"
     CDS             42864..43349
                     /locus_tag="NOB46_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1057998.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            43372..43917
                     /locus_tag="NOB46_001040"
     CDS             43372..43917
                     /locus_tag="NOB46_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HCI1057999.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(43990..45633)
                     /locus_tag="NOB46_001041"
     CDS             complement(43990..45633)
                     /locus_tag="NOB46_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI1058000.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45762..47990)
                     /locus_tag="NOB46_001042"
     CDS             complement(45762..47990)
                     /locus_tag="NOB46_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1058001.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(48023..48502)
                     /locus_tag="NOB46_001043"
     CDS             complement(48023..48502)
                     /locus_tag="NOB46_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058002.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        14828 a         8971 c         9165 g        15742 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgga
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaaactaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgattta tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcacatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaaac cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattacag actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga atgaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attcctattc tttatttaat ggaacaacct gctttgtctg tttctcaatc
    40861 atttttagac aaaaatgaaa tttcttatat gacccatact tctggtacaa ctggtatccc
    40921 taaacttatt tgtcattctg ctcattctat gggatggcgg acgaaatggc aaaaaacagt
    40981 tttcacaaaa atttcggaaa agaaattaat cgcttttcac atctctccag tgcattccag
    41041 attcaatatt ggtatctctt ctttgatgtc catgggattt cctatgatgc ctttagcaaa
    41101 cgcacaaagt tcaaaagttg ttcatatgtt ggaagctcac cggccaattg cactagagac
    41161 ccatccgaat aactttgttc agtggcgttt tactgctaag gagcatccag aagctttttc
    41221 gggtatccga tactatcact ccacttttga tgctataaac aaccagacaa tgaagacatt
    41281 tttgcgaacg tcgatggcac aggatgcggt atttcttcaa gtatatggcc aaagtgaatg
    41341 cggaccaatg attcttaagg ctcatacact agagagtttg aaaacaagtg atgcaagaga
    41401 tatgggcgtt ggactggaag acatgacaag cgctcggatt acagattcag ttgggaatgt
    41461 cctacctgaa aacacagatg gtcatataca attactgtct aaaggacggg ctttgactta
    41521 ttacaaggaa gatgcacggt tccaggaaaa tgtttatggc gattggtggg atagcggaga
    41581 ttacggtttt atggataagc atggccacct atttttgaaa gatcggcaag tggatttgat
    41641 cgaaacgatc aatagtacat tagctattga agacttttta ttagattcgt tagatttttt
    41701 ggcagaagta gtgattgtaa gggataaaaa tcattctcca caaccgatta ttgctttagc
    41761 tcctgataaa gaaatggatt ggaatcgatg gtgggagcaa gtccatgaac ttcctcgctt
    41821 gaacgtccct atcatccgtg attttgatgc aatcccgcga acagctacaa tgaaagtgca
    41881 acggcttcaa atcgagaaag aattaaaatc acaaaagtcc taactattta aggaaagaaa
    41941 gatccatttt ggtctttctt ttctttttgt ttttttaaat tggatgagat aaaaatatgc
    42001 caattggctg tttttctttt ttgaaaattt cgttatactc ttattcatgg aggaaaatgt
    42061 tatgaaaaga atcttgacaa ttggcggttc tgatccattt gctggtggag gaatccaaac
    42121 agatttaaaa acttttgaga attttggtct attcggacta agcgccttga cttctatagg
    42181 ggcactagat attaatgagc gatttatgct ggaatctata tctttggaat tgcttaaacg
    42241 acagttagtt tcgattgata aaatgacttc attagatggt atcaaaattg ggttattgaa
    42301 ttcaagtgaa gcaatcatgg ttgttcgaga cttcataaaa acaaaacaaa atatcccaat
    42361 cattttagac cctgttttgg cattcaaaga aactgaagct gtgatcaatc aattgtatat
    42421 ttcgcagctc atcgaagaac tttttccact tgttacgatg attacgccta atttggcaga
    42481 agctgcttta ctttctggtc aagctcttcc ctcttcgtta acagaaatga tccatctcgc
    42541 taaagaactc actgcttcag gaacaaaaaa cattgtgatc aaaggcggca caaggatggc
    42601 tggagatgaa gctgtggatc ttctctattc aattgatcat tatgaggtat tttctcataa
    42661 aaaaatcgac actacaacag taaacggggc cggttgtgcc ttttcttctg caataacagc
    42721 gaatcttgtg ttaggggcag attttaccaa agcagtagca gaaagtaaaa aatttgttgc
    42781 ccattgtatt tctaatggcg tgctgatgaa cgatcatacc ggaagtgtct ggtctggcgg
    42841 tattcaaaaa ggaggaatga gaaatgaaaa ctaagcaatt aacgatctat gctatgctga
    42901 ttgcgttgac agttgccctt tcattaacaa ttttgatccc tgtaccggct acgaatggat
    42961 ttgtgacatt atgcgaggcc gggatctata ccgctgcttt tctttatggt ccaacgggtg
    43021 gattagttgt tggtgcttcc agtggtctat tgatcgattt gatttcagga tatccgcagt
    43081 gggcagtttt ttcattagtg atccacgggt tacaaggata tgttgctggt tctttcagca
    43141 aatcttctac tcgtatgtgg ggattagggc ttttattagg aagcttagtt atgatcatcg
    43201 gctatggtat cgccggttgg attttatatg attggccggc tggagtggct tctataccag
    43261 gaaacatctt ccaaaatctg attggaatgg gacttgcctt tcctataact gcaagtcttc
    43321 aacgtattca agcacggaag caatattaat tgaaaaagaa ggttttagaa aatgaagttg
    43381 tcagaaaaag aattaaaaga ccaattgact gaaatagtta atgacatatt ggctgaggca
    43441 cacttgaaaa aaggtgatct ttttgtttta ggatgcagca caagcgaagt cgttggagga
    43501 catattggaa aaaattccag tgcggaagtt ggtcaatgga tcatccgtac gttaaaagag
    43561 ttgttggatc ctaaagaaat tgcgctagct gtccaaggtt gtgaacattt gaaccgagca
    43621 ttagtagtag aacgaacagt ggcagaagca aaaaatttcg aaattgtctc tgttgttcct
    43681 gcactacatg ctggaggtgc ttgttctgtt gctgcttttg accagttcaa tgatcctgtc
    43741 gaagtggaac acgtagttgg acaagccggt atcgatatcg gtgacacatc aatcggtatg
    43801 catatcaagc atgtccaagt acctgtcaga cctcgtttga aaacccttgg acaagctcac
    43861 gtgacagccc ttcgctctcg tcctaaatat atcggtggtc ctagagcgaa ttattgaaat
    43921 gagtaattga cagagcaatc tgaaaaactt cctcgcaaag tccaactaat gaactttaac
    43981 gaggaagttt tacttgtttg ttttatataa ccgagcttca taaggtgcta gtatgccttt
    44041 agcttcaaat tctccgctag aggaatttga caagagtaat gtccaggact gatctgcttc
    44101 ttttggaagt tcatagtcag caagtgattc tgttaagttt accataataa gatattgttc
    44161 atcttctaaa tatctttcat agacataaag ttgtggatgt tcatgaagat attctttata
    44221 agaaccgtat atcagacctt tattggtttg tctaatgcgg atcatgttct tatagaattg
    44281 caggaccgac tctggttcat attcttgttg ttctacattg atcgttttgg tatttggatt
    44341 agtgatcagc caaggttcat gtgtagaaaa accagcatat tgttccgaag tccattgcat
    44401 gggtgtcctg ctgttgtctc tcgttgtttc acgaatgata tccaatgctt cttctcttgt
    44461 cttaccttcc gcaagcagcc ttttataaag tcttttcgaa tctactgcat caacttgatc
    44521 gatcgattca aagggcatat tcgtcattcc gatttcctgt ccttgataaa taaatggcgt
    44581 accttgcaaa aagaaataca tcatagcgat tgcttttgca gacatagccc aaaaatcggg
    44641 acgagtatct ccaaacactg aaacggcacg aggaacatca tggttttcca tatataaagc
    44701 gttccatccg ataccatcca atgaagtttg ccaagcgctt aatgcatgtt tcaatttaag
    44761 gacatctaat tgcccttctt tttcttgctg ccagatatgg atatgatcaa attcgaatat
    44821 catatcgaaa taaccgtctt tccctaccca ttgtggtcct tcttctgcag tgacaccact
    44881 tgcttctccg acagtcatga tatcgtactc ttcaaaaaca tgtttcaaat cggtcaaatg
    44941 ttcttcgatt cctgagacat tttgaaaggg tgagaaaggg ttctctgtgg cttttactga
    45001 atattcatct ttttttacat gagaaatcgc atctaaacga aatccatcta tccctttatc
    45061 caaccaccat cggatcatat tgaatagttc ttctttcaat ttctcgcttt cccaatttaa
    45121 gtctggttgt tcttttgcaa aaacatgcag ataatactgt ccagtttcat gagaatactc
    45181 ccaagcagaa ccgccgaaaa tcgatgtcca attattcggt tctttgccat ctaccccgtc
    45241 gacccaaatg taataatcgc gatacgggct ttctttagat tttttcgatt cttcaaacca
    45301 ttgatgctga tccgaactat ggttgatgac aagatccata atcactttga tccctaattc
    45361 atgtgcttct tttagcaata aatcaaaatc ttccatcgtt ccgaatctct cttctatatc
    45421 ttgatagtca cttacgtcat aaccattatc gacaaatgga gattgataga tcggattgat
    45481 ccagataaag ccgataccaa gatctttcaa ataattaagt ttttcacgga tcccattgat
    45541 gtctccttga ccatcgccat tgctatcttt gaaactagca ggatagattt gatagcctac
    45601 tgcttctttc caccattttt gttcttgtat catatcgttt cactccttta acggtccctc
    45661 ttgattataa ccgattctat tttagaagta tccttgttac cggtaactag aaacgaaaag
    45721 ctcaacgaat ctgctaagtg cgttcgctga gctttatttt atcatagata gcgggcaatc
    45781 agttgaatca tttgcttggg aaattcattc aagtcagtaa tatctacaaa acgactttca
    45841 ccgtagatcg acttgatttc ttctttgtct tggccaatag ctgcggagac aaataggatt
    45901 ccttgacgtt catattcttt caaaacagac tggatatctt cttttgcttt tttgcctgta
    45961 taatccggca acgcttttgg ctgaccgtca ctaatattaa gcaacagttt ggttgttgcg
    46021 gattgtctgt ttaatttttc tgctgctaaa cgaagtgcag caccatcacg attgttttgc
    46081 cttggtttca tagtgactaa tttttcattt aaccattgaa atccgtcttc aaattcttta
    46141 taagaaaaca aagaagtctt ttctcttgac gaacggtctg ctgtatctcc gtaaatcaac
    46201 aatgggatat cgactttctt agaaaattcg gcaatggcaa tcgctgcttt ttttgccgct
    46261 tcgatccgat catcccgtat cattgaccca gattcatcga tccgtacagc taccgctaaa
    46321 gaaggttgct catgtggcgg gttctttttg tcaaaatttc tcaaatcacc atatgctact
    46381 ttgcttgcat tgaaccgctg accttcgtat tttccttttt ggtacgtctc tgtttgttca
    46441 ttatccagta actctaaaat ttgccggcta agtgattcta ctattggcat tacttgcatg
    46501 tgtagctcac gtgcttccgg cgtttttcct tggaaagctg gtcggtgaac gatgagacct
    46561 tctttttcat gaatcgtttc cttcatgatt tgtcgcgctt ctttattcag ttgcttcttg
    46621 atttccttat catgtgcttc catgtcagaa gcagacattt cttgagaatc atctcctgtt
    46681 tgttgttctt tttgattttt tccttcgata tcgctactgc gttctttttg catttgagga
    46741 ggaatctcgt ttttttctat tgtttcttct tgtttctctt ctccctcatt tggttcttca
    46801 gcagacaacg atttcttttc atctaagcgc agaatttctt cagcattttc agtgatgttt
    46861 cgttcatttg cttcttcggc gctaatggtt ctttcttttg tatgctcaga ttgaggatga
    46921 ccccattttt cttttctcaa tatgtcctga agttccagta gcaatccact gtcagacaaa
    46981 gcttgttcaa gaattgccaa ttcatctgaa tcagtggata atttatacaa aacttttgga
    47041 taaatcgact ggagtaaatc ttgtccttgc ttataggtat ttgcccaata aaaataagaa
    47101 cgcattcctg ctacaccttt gatggcgtta gcttttgcag tttcatccaa caaacggata
    47161 atctctgcca tctttaagag aagttcttgt ttttggatca tagttttcgc catcgcacgt
    47221 tctgccatga cttctaaggc aggaagatcc attttttccg catgttgcat ccgatctctt
    47281 aaagattcat ttaatgggcg atttccttgg taatttcgat ttgtagtgat cacaatgacg
    47341 caatctggat ggcgacgaat gattcctgtc ggtaaattca acatcccatt tggttcgagc
    47401 gctgagttaa gtgccacaag aacagaggca tctcggatga cagtcggctc ttgaatctct
    47461 aataaatagc ctttttcaat cgctcgaacg atttcagaag ggtaatagct gtaatggatt
    47521 gcatctggat aatcagcttc gatcctttga actagctctg ctaatttttc tttagcagaa
    47581 aaaggatcaa tgccgtaatg gttctggatc agtgtcagta cagcttcaag tgtatctgtt
    47641 tggtaaatag cttctagtaa ttcttggtct tgttccttat tagaatctac tacaggtaat
    47701 aaggctccga aaacatctga tttgtccata tctgcaaaac aggtcacttt tgtataggga
    47761 agttgcagat cagcagatag tgctttggct aattgtgtct tccccgaccc ggcatctcct
    47821 tccaaaagta cgttactgat tttcatttca ggatcttgcc aattcccttt gatttcggag
    47881 gcgatccgcc attcttctgc acttgtccga tggcttttcg gtttcttcca gatcatttgc
    47941 ttttctagcc gtgaaaaggt tcggttttct gttagtgaga aattctccat gcttctcttc
    48001 cccttttgat catctctgtc tattaatatc ctagctcatc taaaagacgt tttaaaatac
    48061 ggaatcgttc cccaatcagt tctccgtctt tttgtagtgt atcgtaatac aaaatgatgt
    48121 cttcatcgat ctttggattt ttggtatcta cttctaccgt cattcggttc ccttgtaatc
    48181 caatgatgtc tacgactgga ttttctggat cataaaattt ttcataacga taagcatctt
    48241 ggaagtataa acttccttgc gcagctaaga tcgctaaatc taaaatacgt gtgattggta
    48301 attcttccga ctgtcgtgac catttttctc cagtatgtcg ccataccttg cctgagatat
    48361 cgacttttcc acgatcattc cactgagcaa ggcccagtga aagccctttt gcatccatat
    48421 ttaatgcatt tcttccatca actttatcat agtcttctac aacgattact ggtttatgtt
    48481 ttaaatttgt tggtatttcc attattttaa ctcctcatcc ttttattttt agtaaataag
    48541 taaattagta gtttactcat ttactaaact atatgcgaca ttatagagga ttgaagtgag
    48601 gattgcaaag aaaaagagct tcattgatag aaataaaaac accatctcgt tcttttacac
    48661 gctcattagt aacatgtaga aagtccaaga tgatgttgga atattt
//
LOCUS       DAIGUC010000018        48524 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.018, whole genome shotgun sequence.
ACCESSION   DAIGUC010000018 DAIGUC010000000
VERSION     DAIGUC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.018"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(280..495)
                     /locus_tag="NOB46_001044"
     CDS             complement(280..495)
                     /locus_tag="NOB46_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058003.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            complement(547..1461)
                     /locus_tag="NOB46_001045"
     CDS             complement(547..1461)
                     /locus_tag="NOB46_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058004.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            complement(1461..2360)
                     /locus_tag="NOB46_001046"
     CDS             complement(1461..2360)
                     /locus_tag="NOB46_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HCI1058005.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            complement(2360..2947)
                     /locus_tag="NOB46_001047"
     CDS             complement(2360..2947)
                     /locus_tag="NOB46_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058006.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            complement(3111..3302)
                     /locus_tag="NOB46_001048"
     CDS             complement(3111..3302)
                     /locus_tag="NOB46_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058007.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            complement(3375..4277)
                     /locus_tag="NOB46_001049"
     CDS             complement(3375..4277)
                     /locus_tag="NOB46_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058008.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            complement(4294..4770)
                     /locus_tag="NOB46_001050"
     CDS             complement(4294..4770)
                     /locus_tag="NOB46_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058009.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            complement(4786..5385)
                     /locus_tag="NOB46_001051"
     CDS             complement(4786..5385)
                     /locus_tag="NOB46_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCI1058010.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            complement(5389..5442)
                     /locus_tag="NOB46_001052"
                     /pseudo
     CDS             complement(5389..5442)
                     /locus_tag="NOB46_001052"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5944..6423)
                     /locus_tag="NOB46_001053"
     CDS             complement(5944..6423)
                     /locus_tag="NOB46_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058011.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            complement(6442..7071)
                     /locus_tag="NOB46_001054"
     CDS             complement(6442..7071)
                     /locus_tag="NOB46_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058012.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            complement(7068..8444)
                     /locus_tag="NOB46_001055"
     CDS             complement(7068..8444)
                     /locus_tag="NOB46_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HCI1058013.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            complement(8524..9786)
                     /locus_tag="NOB46_001056"
     CDS             complement(8524..9786)
                     /locus_tag="NOB46_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058014.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            complement(9799..10146)
                     /locus_tag="NOB46_001057"
     CDS             complement(9799..10146)
                     /locus_tag="NOB46_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058015.1"
                     /translation="MEIISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            complement(10166..11035)
                     /locus_tag="NOB46_001058"
     CDS             complement(10166..11035)
                     /locus_tag="NOB46_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCI1058016.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            complement(11267..12073)
                     /locus_tag="NOB46_001059"
     CDS             complement(11267..12073)
                     /locus_tag="NOB46_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058017.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(12161..12961)
                     /locus_tag="NOB46_001060"
     CDS             complement(12161..12961)
                     /locus_tag="NOB46_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058018.1"
                     /translation="MVEISKTTLDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            complement(13300..14409)
                     /locus_tag="NOB46_001061"
     CDS             complement(13300..14409)
                     /locus_tag="NOB46_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1058019.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKPETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVLGALASLKVLILLIKEFRKA"
     gene            complement(14399..15262)
                     /locus_tag="NOB46_001062"
     CDS             complement(14399..15262)
                     /locus_tag="NOB46_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1058020.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            complement(15331..17166)
                     /locus_tag="NOB46_001063"
     CDS             complement(15331..17166)
                     /locus_tag="NOB46_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI1058021.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            complement(17215..19605)
                     /locus_tag="NOB46_001064"
     CDS             complement(17215..19605)
                     /locus_tag="NOB46_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HCI1058022.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     KFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNTLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            complement(19595..19738)
                     /locus_tag="NOB46_001065"
     CDS             complement(19595..19738)
                     /locus_tag="NOB46_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058023.1"
                     /translation="MLSTKKVINRCGDFNLGMGAKVITTPTYRGSFSSPNWYKEGVTR
                     DEA"
     gene            complement(19875..21122)
                     /locus_tag="NOB46_001066"
     CDS             complement(19875..21122)
                     /locus_tag="NOB46_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCI1058024.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETAKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTETDTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            21514..21930
                     /locus_tag="NOB46_001067"
     CDS             21514..21930
                     /locus_tag="NOB46_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058025.1"
                     /translation="MNKKRKLSVLITLVSILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETVTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            complement(21965..22038)
                     /locus_tag="NOB46_001068"
     tRNA            complement(21965..22038)
                     /locus_tag="NOB46_001068"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22002..22004),aa:Asn,seq:gtt)
     gene            22169..23317
                     /locus_tag="NOB46_001069"
     CDS             22169..23317
                     /locus_tag="NOB46_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HCI1058026.1"
                     /translation="MSKHKHQKRKKNKLTLVFPLFLILLAFSGMYAEHSYPEHHATKK
                     SSTPATKTTTDLTNQQPIEPKNATSAGIEQLLVEKNFSGTVLVFQHGQVILNKAYGWK
                     DQARRIHNTIHTQYCIGSVQKGQTAYLIMQAVKSGKISLEEKLSTFYPQISNSEKISI
                     KDMLNMSSGLRIDEKKIAALNTTDPQKILSETIRQTTVAANSSYSYQPVNYVLLAGIL
                     EQVYHTDYSTLFDKLLRKPMKLKETSFYSETNNQQALSYSESSSGPVYAPTTVSSYAD
                     ELGTGNVFMSGEDLYSYFQDLYQDKFLTTQERAALWQSYPGEKYASGIYNMTNNYHSR
                     GVKARFEALVDFSKDGQNGIILLSNVWTQPKGYNDIVSKLYKQVVAGS"
     gene            23435..23507
                     /locus_tag="NOB46_001070"
     tRNA            23435..23507
                     /locus_tag="NOB46_001070"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23468..23470,aa:Thr,seq:ggt)
     gene            complement(23511..24187)
                     /locus_tag="NOB46_001071"
                     /pseudo
     CDS             complement(23511..24187)
                     /locus_tag="NOB46_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181200.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            complement(24296..24889)
                     /locus_tag="NOB46_001072"
     CDS             complement(24296..24889)
                     /locus_tag="NOB46_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1058027.1"
                     /translation="MDFNEKLKQLRQNKQWTQEELAERLFISRTAVSKWESGRGFPSI
                     DSLKAISQVFDISIDELLSNSELLSIAENEQQQQRKNFQHLLLGISDCMVGLLIVLPI
                     FGQAQGNHIAFVSLWQLSQETIIFKLIIFSFVILTMLFGIFELAFSRREQRIIGSVSL
                     ILSLFGVLLFIMTRHPYPATYVLMLLAVKGISLLNSR"
     gene            complement(25033..25437)
                     /locus_tag="NOB46_001073"
     CDS             complement(25033..25437)
                     /locus_tag="NOB46_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI1058028.1"
                     /translation="MGKQLVLVSHGLFCEELKKSTEMIMGPQESIHTVSLLPAESAED
                     FRAKFEAVIADLDDFVVLADLMGGTPCNVVSRMILEGQAIELYAGMNMPMVIDFINSE
                     LIGTELALVESATSNICHVNERIIGDDDDEDE"
     gene            complement(25475..26284)
                     /locus_tag="NOB46_001074"
     CDS             complement(25475..26284)
                     /locus_tag="NOB46_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1058029.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEIMKTHTQFFNTSNFFNTIVTGIDLAIEEKEGIGGKDTVSGMKA
                     GLMGPFAAIGDSIFAALIPTIFGALAANMAINGNPTGIFIWIIAQIAVMIFRWKQLEF
                     AYREGISLVTTMQHRLTALTDAATLLGVFMVGALVATMINVKFSWAPSIGDVTLNMQN
                     NLDMILPRLLPAGIVAAIYWMLGKKNMTSTKAIFIVLVVCVALSALGVISK"
     gene            complement(26271..27167)
                     /locus_tag="NOB46_001075"
     CDS             complement(26271..27167)
                     /locus_tag="NOB46_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1058030.1"
                     /translation="MDILWWQILLLTLYAGYQILDELQIYSSLSAPVFAGLFAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSVALGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDKLVEDMNYKGIERNFLMGAIPWSFSRMIPVFLAL
                     AFGGGLVEKVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHFPYLILGFT
                     LTALLGTVFTNMQVLGTGVAGVVKNFEGIFNSLPMLAIALIGFALAAISYKNGQMIPS
                     SPAPKEVASNDSDEGEIEDDEI"
     gene            complement(27180..27659)
                     /locus_tag="NOB46_001076"
     CDS             complement(27180..27659)
                     /locus_tag="NOB46_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HCI1058031.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNITRIMVVDDEVAQNDIEK
                     SGLKLATPAGVKLSVLPIEKAANNILAGKYDSQRLLIIARKPDRLLKLVELGVPIEEI
                     NVGNMSQTDETRSITKSINVVDQDVEVFNQLHAKGVRLIAQMVPSDKAEDFMNLLAK"
     gene            complement(27662..29440)
                     /locus_tag="NOB46_001077"
     CDS             complement(27662..29440)
                     /locus_tag="NOB46_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HCI1058032.1"
                     /translation="MKTFEIKEDFLLNGEAFKIMSGAIHYFRIDPADWYHSLYNLKAL
                     GFNTVETYIPWNLHEPKKGEFHFEGILDLERFLSIAKELELYAIVRPSPYICAEWEFG
                     GFPAWLLNEDTRIRTNEIGYLKHVADYYDVLIKKLVPHQLSNGGNILMIQIENEYGSY
                     GEEKDYLRSVRDLMINRGITVPFFTSDGPWRATLRAGSMIEEDILVTGNFGSKAEENF
                     ASMQSFFDEHGKKWPLMCMEFWDGWFNRWKEPIVQRDAEELAEAVKEVLIRGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLNEQGNPTEKYFAIQKMIHDTFPEIQ
                     QMEPLTKNTMEVKGIHLRNKVSLFSTLDTISQPVKTTYPETMEMLGQNTGYILYRTSI
                     KKDAEEERLRVIDGRDRSQLFLNQKLQATQYQTQIGEDIIVPMTEETNQLDILIENMG
                     RVNYGHKLFADTQNKGIRTGVMADLHFLTDWSQYCLPLDSCEAVDYSREWQPEQPSFY
                     RYEVVLDEVEDSFIDLSNFGKGVVFVNQVNIGRFWEVGPTLSLYIPKGLLKEGNNEIV
                     IFETEGTFQPEIQLVKKPLYKEMKEG"
     gene            29611..30321
                     /locus_tag="NOB46_001078"
     CDS             29611..30321
                     /locus_tag="NOB46_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1058033.1"
                     /translation="MVIPKYQIIKDELKQQIISGKFENGDKFYTEAELAEMFSVSSIT
                     VIRALNDLVKDGFIVRHQGRGSFVSRARKGKIVEFSDIELFPISNDQVQVLSITRGND
                     PVYLSKLELPDTAFYYCIKRLRKAEETPYIYQQTYLPEQYVNPNYQELSYYNSIYQRF
                     KLDYNIHMNEEDFTETNEIKFPTPSDAAKLLEISADEPTVLQVRVTKRRDTQQMLEYV
                     ESYKKWNFYKIELVSKNN"
     gene            complement(30552..31514)
                     /locus_tag="NOB46_001079"
     CDS             complement(30552..31514)
                     /locus_tag="NOB46_001079"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HCI1058034.1"
                     /translation="MIVTVTMNPSIDISYPLEKLKLDTVNRTDQVSKTAGGKGLNVTR
                     VIHDLKGDVLATGVLGGFHGAYISEELKKAGIKQAFTEIQEESRDSIAILHEGNQTEI
                     LEAGPTVSEAEQQAFLENFQELVKEAEIVTISGSLAKGLPLNFYQRLVQLAEEQVVKV
                     LVDTSGESLRQVLTGEHKPFLIKPNLEELEALLGQPFSIDDLEELQSALAQPLFTGVE
                     WIVVSLGKDGALAKYRDSFYRVTIPTIKTVNPVGSGDATIAGFAYGLSQKMSVTELLK
                     LCMAAGMANAQEVRTGHVNLANVDMHFEEINVRKASRTRSAFEQ"
     gene            complement(31526..32533)
                     /gene="lacD"
                     /locus_tag="NOB46_001080"
     CDS             complement(31526..32533)
                     /gene="lacD"
                     /locus_tag="NOB46_001080"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI1058035.1"
                     /translation="MLTLTTGKKAAMDRLSTKDGIISALAIDQRGALKKMIKALNVEP
                     TDKHIEHFKELVSSELTPYASSILLDPEYGLPAAKVRHADAGLLLAYEKTGYDATTPG
                     RLPDLLADWSVLRLKEQGADAIKFLLYYDVDEDPAINHQKHVFVERLGSECAEEDLPF
                     YLELVSYDAQISDAGSFDYAKVKPHKVNDMMKEFSKPQYKVDVLKVEVPVNMNFVEGF
                     GTGEIAYTKEEAANYFLEQSQATDLPFIFLSAGVSTELFQQTLVFAKEAGSTFNGVLC
                     GRATWKNGVKPFIESGEAAARDWLQSEGRENIESLNNMLKQTASSWHDKVQVAEEEAV
                     N"
     gene            complement(32556..33728)
                     /locus_tag="NOB46_001081"
     CDS             complement(32556..33728)
                     /locus_tag="NOB46_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1058036.1"
                     /translation="MFTIEKEKLEQMGAEITTREIRQQPELWKETIDLYQSAQGELEN
                     FLTEVQKQAKGQRTRVIFTGAGTSQYVGDTLVPYLRKHGDRQAFSFESIGTTDIVAEP
                     EEYLIKEEPTLLVSFARSGNSPESLAAVEIANQVVDTIHHLSITCAKEGKLAQISQAD
                     SKSFLFLMPVRSNDDGFAMTGSFSCMTLGALLTFDQTALAEKQNYVETLNALGNEVIA
                     REHDIEEIVALDFERIVYVGSGSLAGLTREAQLKILELTAGKIATVFDSSMGFRHGPK
                     SFINEKTIMFGFVNNDPYTRDYDLDILEEVHEDEIASGVFAITQPGKRNFSGDTFEFA
                     TGTSLLPDAYLALGYVMVAQTVALLTSVKVANTPDTPSPTGTVNRVVKGVTIHDYK"
     gene            complement(33741..34472)
                     /locus_tag="NOB46_001082"
     CDS             complement(33741..34472)
                     /locus_tag="NOB46_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1058037.1"
                     /translation="MENSFKNKALYHQLVDLLKKRMESGMIPHDKLPSERELTAQYGV
                     SRTTVRLALQELENTGYIYRRHGKGTFVSDIKTAAADLAGAYSFTEQMKSLGRHPETR
                     ILSFEKMEADKFIAQRLNLPLGEAVFKLSRLRIADREPLMIEDSYLPVKFFLSLDDQL
                     LRSKPLYDLFSEDFKQTVRLADEELYASIASKDDAKQLMIPEGAPVLHLVRQTYNMKN
                     EIIEFTLSVARADQFHYQIRHIRNS"
     gene            complement(34928..36247)
                     /locus_tag="NOB46_001083"
     CDS             complement(34928..36247)
                     /locus_tag="NOB46_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1058038.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKHGRKIRLVVKREVNKFRYCGD
                     IRKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGVVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEDYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRKQYEEEKEKTFKAIRWDWGRQREIYMSKLW"
     gene            complement(36364..37101)
                     /locus_tag="NOB46_001084"
     CDS             complement(36364..37101)
                     /locus_tag="NOB46_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058039.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANHQD
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(37524..38087)
                     /locus_tag="NOB46_001085"
     CDS             complement(37524..38087)
                     /locus_tag="NOB46_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058040.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLENLDSYVRAE"
     gene            complement(38074..38601)
                     /locus_tag="NOB46_001086"
     CDS             complement(38074..38601)
                     /locus_tag="NOB46_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058041.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSDKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            complement(38624..39961)
                     /locus_tag="NOB46_001087"
     CDS             complement(38624..39961)
                     /locus_tag="NOB46_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HCI1058042.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVSGDVAKNIDDIYKFMNGEYGLSGATIAGILGNWKQESGNDPRTVEG
                     YYGDGQREVEFIKQFTDGLMGIGYGQWTAGRHTALVNWAKKNFGGAWWTTEAQLDFMF
                     KGDGGFVAILKDYALNASDDVVANAVAFHKNWEISADSESAVVAVRGGNAKEIWEYMK
                     SKGMDGAKDVSKINKIAGGTSTGGGSNNSSSSASGTVEDACATTDDANSGSGSMGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            40081..40559
                     /locus_tag="NOB46_001088"
                     /pseudo
     CDS             40081..40559
                     /locus_tag="NOB46_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(40674..40906)
                     /locus_tag="NOB46_001089"
                     /pseudo
     CDS             complement(40674..40906)
                     /locus_tag="NOB46_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(40909..41226)
                     /locus_tag="NOB46_001090"
     CDS             complement(40909..41226)
                     /locus_tag="NOB46_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058043.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            complement(41337..41519)
                     /locus_tag="NOB46_001091"
     CDS             complement(41337..41519)
                     /locus_tag="NOB46_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058044.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            complement(41556..42356)
                     /locus_tag="NOB46_001092"
     CDS             complement(41556..42356)
                     /locus_tag="NOB46_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058045.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            complement(42493..42912)
                     /locus_tag="NOB46_001093"
                     /pseudo
     CDS             complement(42493..42912)
                     /locus_tag="NOB46_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(42908..43216)
                     /locus_tag="NOB46_001094"
     CDS             complement(42908..43216)
                     /locus_tag="NOB46_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058046.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            complement(43378..43908)
                     /locus_tag="NOB46_001095"
     CDS             complement(43378..43908)
                     /locus_tag="NOB46_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058047.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            complement(43924..44289)
                     /locus_tag="NOB46_001096"
     CDS             complement(43924..44289)
                     /locus_tag="NOB46_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058048.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            complement(44295..45038)
                     /locus_tag="NOB46_001097"
     CDS             complement(44295..45038)
                     /locus_tag="NOB46_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058049.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            complement(45169..45891)
                     /locus_tag="NOB46_001098"
     CDS             complement(45169..45891)
                     /locus_tag="NOB46_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058050.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            complement(45897..46142)
                     /locus_tag="NOB46_001099"
     CDS             complement(45897..46142)
                     /locus_tag="NOB46_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058051.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            complement(46153..46737)
                     /locus_tag="NOB46_001100"
     CDS             complement(46153..46737)
                     /locus_tag="NOB46_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058052.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            46859..48442
                     /locus_tag="NOB46_001101"
     CDS             46859..48442
                     /locus_tag="NOB46_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058053.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
BASE COUNT        14121 a         9975 c         7200 g        17228 t
ORIGIN      
        1 ccatctttaa agaaatacga tcaaaaaaca taattcccat attatttgct cgttcaacaa
       61 tttgaaatat atctattagt tcttcttttt tcataactgc tcttccttta acttgttaat
      121 ctaacttgct tacaaatata tcctaccaca tttgtgtact atctgtcaat atttttttgt
      181 gtataaatgt gtattataaa acaaataatt ttacacaaac aaaaaagagc ctaactgctc
      241 ttagcaataa gctctcatca ctgctcctcg tgaatttagt cagtacaatg tatttgcctt
      301 ttctttgata aaatccttat acgaaaaatt gttcaaccaa aattgtttta gcactaccga
      361 atttttgttt ccatcattca actccaattg accaaatctg ctgatcatat catcaatttc
      421 atcaattatc tcttgtgcca tcatgccgtc ttctagacgt tctaatacgt acaattcaaa
      481 aacatccctt ttcattcaaa atgccccttt caggttacct tttgccattt tatgggctaa
      541 ctccgcctac tcagcttttt ttatatacct actgatattt gctttcgtat ttcttggcat
      601 accacctgct tgcaggtaat gttcacgata ataagcatct agctctgaaa cagctttttc
      661 taatctattc gttgcattca acactgagcg gtattcacgt ttttccctta atacacgtct
      721 taaatggttc atcgctgata tataaggctt atagtattcc aatacagtat atcctctaga
      781 aatataggca attggatttc tagcttcatg gatcaattct aaaatatctg ttggatcagg
      841 cttatccggc atctcttctt cgatttccat aatactgatc aagtagtcca atccggaatc
      901 atcgactcca taactttcac accattcttt taggttgttc aagtcatgaa taacatcttc
      961 aggatcaaac tctctaaaag cagtgatccc ttggctataa tattttatat attccattgc
     1021 cgattcaaaa tcctctggcg gtatgaaagc ttcaatttct tcttcatcaa tcgctttcag
     1081 cactattccg atacctgagt ttgaaggata ttttctcaat ccttcttcaa ttaaatcctc
     1141 atctattcgt cctttttgaa acatcaccaa taattgttct aacagctgat ctaaaaccct
     1201 gcgctcttca ttcagttcca ttgcattttt aacttctttt tcaccgagtt caaagtaagc
     1261 tttgatcaac ttttcttgtt cttttcgttc aactaatttc ttcttcaagt cattcatatt
     1321 gagaatgaaa tccatgtgat tactcttttg ctgattgaca aaatcatatc tttgttccaa
     1381 aacatcccga tattttttta gttcttcttg aattatttca aagctatcaa gtacatgaag
     1441 aattttttca ttattattca tcagcccatc tcctgtagtc tcacgtttgt tttcgacttt
     1501 tcaaaagtat tgtatttaaa agcaattaac cctacaaccc tgctatcttt gatgcctatt
     1561 tccttgttaa aaattccgtc caatgttcct ttgactaaat tatcaatatc cggctgtgaa
     1621 gtacgcatca gtgaatcaag ctttttctta tcttttctca cttggtaaaa ataatctatc
     1681 tgagctataa cccccatagg agcattcatt acctttttca gttgatcatt taccaaatct
     1741 ttctctttaa gcgtattctt gatattttcc aaatagtcgt tgtactcttt tggatagtaa
     1801 gtgataatcc catttcctct aaatttagac tttggtcttg gcgttgctac tggtttaaaa
     1861 tcaaatgtag cttcccatat atctccgttc aatccttcag aagtatccca ctcaaattct
     1921 gaatatcgtt tgatcctcac aactgttttt ccttcgttcg ccacattata tttaaaagca
     1981 attaagcctg tgatatggct atctcgtata gctgagatgt taaaaatacc atccatagca
     2041 ctttttacta aattatctaa atctggcgct gttgtcttca taatgttata gactttttta
     2101 tagctttttg gtatctggta gtaaaagtcc acttccataa ttgcgcccat aggatcattt
     2161 acaatcgagt aaaattcatc atctaataaa tcttgatctt cgataaagct ctttattttt
     2221 ttcaaataat caagatactt tttatcatag taggttgaaa tccttttctc tgctacgtca
     2281 ttagtttcat cagcagcatt ccttcttgca cttggtcttg gtgcagatac aggttggaac
     2341 ggtaaagtta cagtccacat tagtcttttt tgatctcttt caaatagatt tttttaaagg
     2401 tatcaaggct taaaggagct accttttgca tcttccggat tttatttact tgttccaatt
     2461 gtttcaatag accatcttct tttctaaggt actcaggatt tgttatttgt ttattccgat
     2521 actcgattaa tgattgaagc tctcttactg ttaaaacatc ctcaattttt gcttctttac
     2581 tcgttatctt ttttagatac cctaatactg ttggataaga tttgccgatc acttctgcga
     2641 tttctttttt attgtactca ccaaattttc caagcaacca gtcattcatg atcttacttg
     2701 atacttttgg gtatacaaga attgcttttt caatggaatg actgccatta tttctgatca
     2761 gttgactatc tttacactca actgtaacgc catcacctaa atcaacaaca tattgccaaa
     2821 cgcctcttcg attcttatta agagaaataa tcgttccctc tttatctcta taatcctttg
     2881 ataattcact tactgttgta actctttccc caatgctaaa atgtctaata tcattattgt
     2941 tttccactta ttatccctcc aatattgctg gttatctctt cctctgacaa ggaactatat
     3001 atcatataaa gaattttaac attattcgga atgagtgtaa agaaacttta tataaaaaga
     3061 gtgatttagt ctaagaccaa atcactcttt cttttttatt aattatattg ttatctgata
     3121 gacctattag taaatgcacg tcttattgtt tgatcattct cgatcaattc ttctaacaac
     3181 tctgaaactg ttactttctt acctcttgct ctttcttctt ctttagctcg cttttctaaa
     3241 tatttaacag aagctatttt taaagtcaca tactttctaa ctttttcttt atttactacc
     3301 atcagctatc atctccaagg tgtcacacct atatattatt ggtgtgacac catttgttta
     3361 ttataacttt ctggctattt agccaattta atcgttaatg cttcgtttgc tgtagaatct
     3421 ccaaaaactt taccgtcttc ataaactaca tgaactggca aatctgcacc gtctgaatct
     3481 ggtttagcag taccacgata caaaccaatt actctttttc ctagttctct tgcaaccgta
     3541 acttttttat cctgatccat agattcaact gaattgaata aggtaacatt aatcatttgc
     3601 ttttcagtat ccaatttaac agttttgata gctttgaaga cttcagtgtt aaaccgatca
     3661 gccatagaac cagaaacaga ttcaaacgat ttgacttttt caggatcaaa atcaatttta
     3721 tctggtagtt ccgcttcgac agtagaactt gattcagttg tactttcttc tgtagctact
     3781 tcttttttcg ctgattcgat aatctttttc gttgatgttt tatttatttt tacatcttta
     3841 tagtattctt ctccatcaac gttaaaaacc aatgtcagct tgtgtacagg gctattctct
     3901 ttaactgtat aaaacacttc aaattgtgat tgagacggct taatagtagc gagaacgtcg
     3961 tctgatgctt tcttgccatc ttccttcact gtcagcgaaa catttttata actcgttaca
     4021 ttttcaaatg ttccatctat tactaccctt cccaaagaat ctggagcata actattatta
     4081 actcccgata taccaaattg tttatcgtta cttccaaaaa tcttagtggc attaaacaca
     4141 ataaaggtta caatcacaat tccaatgcct atgttacgca taatcggatt atttgtttga
     4201 aattgaccaa taattatagc gattgcccca aaaaaagcaa gaattaaaca taaataacct
     4261 aacagggtta atagcatgat tcatcacaac tttctattct ttatttttct ttttggtttt
     4321 cgtttgttca aactcatgct catttagata agtaatcaat aaatctcgca tggatttgct
     4381 atccttactt agcgtatcaa acgcttcttg taagtcagca tccttctcta cagcattaaa
     4441 ccaatgcttc gttccaaatt caaaaagatt actaatcact cttaacggtt cttgatcagt
     4501 attcgtatta agccattcaa gtatccgttg ttgagctaat cctaatttac tttcgtcttc
     4561 gtgatttgta cgtgcttcat agattttagt gtgtatatca tcaaaatagt ggattcgttc
     4621 tcttagcgct tcacgttgtt cgtacatagc ccttttattt ctaacttctt cgtctattgt
     4681 ttcaatcttt tttcttaaca gtatttgaag tgataacatt tctgagacag acaaaaacac
     4741 tggaattttc ttttcttttc tttttggcat ttttagcact cccttttaat tcttttgttt
     4801 gatcaatgaa acgttcttta gaataaatcc caagatcatt ccacagacaa atccgattac
     4861 atgtgacaag acatttgcct cgcctgattc aaaagtagat accaataaaa tgccgattat
     4921 caataataca aaaacactta gtaataaatg tttcttgcta tcaaaacgga tgtatgcaat
     4981 cgcaaataaa gcaatccatc caaaaatacc tccactaagc cccatactta cgatgttgct
     5041 gtgtagcaga aaaggaacta agcttcctag aaatcctgat atgattaaaa cgatcaataa
     5101 tgttaaccac tcatactgat cattcagtgc ttcttcaaga actactaaga acaataaatt
     5161 agaaattaaa tggtacaagt taatatgaga aacgatagaa atgaatatat tcgggaacaa
     5221 gtgtccttca tacaaaccac ctaaagcaac catttccttt gcactcaatg tatttccaat
     5281 tatgcttttt ccaatctgca aaaaatcaaa caggaaaatc aatacacaaa caaaaactac
     5341 agtcgctact aggtatcgac tactattttt gtttttttct ctcattcgct acttcctttg
     5401 ctttagtaac tgccgattct ccatattctc taaaaagagt cgatgttagc tttcctctcg
     5461 gaatattgta tttttttaaa atttcagttg ttgaaagatt tttttcaaag tcttcaataa
     5521 tttgtttatg aagatttatt ttagccaaat cattggttgt caaaacaggt tctttagctt
     5581 gaatatcgcc ttgacgaatt aacctttgaa ttttattttt gctttttaaa aaaggatatt
     5641 tttcaattaa agggtcaatt gcattccctt catcaatcca cttacctatt tcttgataaa
     5701 ctctcttttg aaattttttc ctcagctcaa tcgggttcgg aaaaacattg tgcttaaaat
     5761 cgtgtgatac taggctcttt gatttgccta attcatcagc gacttcttgc attgtaattt
     5821 tgttttcgat atagcattgg acaagagcat tatatttttt agggttatta ttatttattg
     5881 tcatgttctt acctacgttc attgctaatt ttttggtatt tttctgtttg tgtattgcga
     5941 tttttaaaag gcatttccta atacgttaaa ttttgataat cggttcaatt ttactgcttt
     6001 atcaatttct gcctgtgacc aaggttctat taaacgcatt tggtacgtca ctagcagatc
     6061 gacatgttca tattcaaact tttctattcc gtaaatctga taaaatattt tttcttcgtt
     6121 gttactataa ggaatcactg ttccgatctt aaatatgttt cgtgtgttgt ttacaccaat
     6181 ttcatcagta atcttgtgtc tatattctaa taacacgtat ttcttatacc tgcttgtcag
     6241 atcaggtgaa tagttaacag attgacaaac caagtcactg gttatacgtg gatcacctat
     6301 tctgttaatt ctcgtgttat agattccgat aataatatag tttttatctt tatattctat
     6361 agtttctccc acttctaact tttgattaaa gcctgttcta tttgcttcaa aaagttctag
     6421 caatcttttt cacctctact gctactgcca aacaaattta gctttatcat gccatgtttc
     6481 agacattact tttttaccat tttcgtcaaa tatcaccgct tcccactttg ctgttccatc
     6541 cggctgttta caaatatctg caaaccatag gatcgttttt cgatcgttga atttccttac
     6601 tttcttctca aatttattga tctgaactct attttgattg ctgttccaac ctactaatag
     6661 gcggttatct gattctgtac catgaaaacc aatgggaacg atgtgggttc tatcaaatgc
     6721 ttcttttcct tctggataga gcattggtct aagtttccta cgtttcaagt catctcttgc
     6781 ttgataccgc catgccgatt ttggattgaa tttaatagct atttgatgct tgcttttgtc
     6841 atggtaaaaa tatgcgacat cggcttcagc tccaagcaac ttttctcttg cactatttga
     6901 ttcaaacggt ttattcactt ctaaaacctt cacccctaaa atgccatgat caagcatctg
     6961 tttaggagtt agtaccgctt ttttatctct tttcttcgct cgtttcacaa ctacttcatc
     7021 tgtatattta tatggagtaa gccatcttaa aaaagaactg acgatgatca tttatgcacc
     7081 tgtttttttg cttttaacat tttttgcatg ataggtgaag tacttccatt tatttgtttc
     7141 ttttcagatt tatcagttgt gatcactacg ttttctgagc cttttggatc attagcttta
     7201 ggtttggttt tagatgcaat cggctgttta ttattcgtgt tgtttgaggt ttgcggttca
     7261 ggatcagctt ttcctaatgc ccttaaaact ttttctagtt tttctgcttg cagtttttct
     7321 agtgttttag ctccctgctc gactttttct tctttgttct tttcaagctt aatagcaaac
     7381 gcactcttct tttcaattga tggctcttta gatgatggat ttgctaaagg tgtgttcaaa
     7441 tttcttttag cagattttct tacaggagct ttaccaattc caccaaaatc ctcgtcttca
     7501 ccgccctcac cacgagtttc agctacgatt gctcggtaat caacatattc tggttctggc
     7561 atagtatttc taaggtgatt gaagattgtt tcaatttctt tgttactgat gtaagctccc
     7621 tgcgctctaa ccatacttcc atcaacaagc ttaataagca tatctccctt tggacttaga
     7681 ctttctccac cgccttcatc taatacaatc ctactttcta aatcacttgc taccataagg
     7741 caaacacgtg acggaaaatt ggctttgata ataccagtga caactgttga tcgaggagat
     7801 tgtgttgcta agataacatg aatacctgct gcccttgcca tttgtcctaa ttgaacaatc
     7861 aaaccttcta cttctttatg tgttccaacc aactgtgaat attcatcaac taataagatc
     7921 acatagggaa atctatctaa tccatttttt tcggcatatt cgttatatag cgtgatgttt
     7981 tgtaaccctg ctttttccat cagtttgtaa cgttcatgca tcaagatcac aagatattca
     8041 aaaaaatcat aagcttcatc catatctgta attggatcag ccaacatgaa cggcaatttt
     8101 ttgtatcttc caaattcaac cctttttggg tctacaattc ctatttttaa ttcatcaggc
     8161 gttgagtgac acattactgt aacaagaatt tcattcagta atactgattt ccctgatcct
     8221 gtcgttcctg caaccaacat gtgtggcatt tcgctgatgc aaaaatgagc aattgtgcca
     8281 tcaggcttaa ttccaaaaat agcatctgtt gggtctttag cctttgtgtt caacatattg
     8341 acactgaatt ttccattaag ctttatatta ggttctttat ctagcaaaat agattcagct
     8401 ttttcggctc tctttttgac tttctctaat aatttcatag ccatttctat tcctcacttt
     8461 tctcggtact tttctgtttg tgaactggta gtttgtattt tctgtttcta tttgtgatgt
     8521 cttctaaaac acgctattga tcattgatgg tacatcaatt ggaatacgat cattttctcc
     8581 taatggtaaa gtaatttgaa tacgccctgc gttgatccgc acgattacac ctgatatatg
     8641 caagtaagtt tcaatttctt ctttcattga gcttagttga atttttctgg tacgagataa
     8701 agtaaacaaa tattcaatag atgtattccc aacgtgcata tctgttagac ttgcaggtac
     8761 gtcagcagaa gatagataaa gttctaaaga ttgcttttga gtttcggcat attttctagc
     8821 tttttcggtt tggttttgga tatttttgga attatcggca aagagattga ttggaaaaga
     8881 aaattgtgaa tttgaaactg cgattgaaga tgttgctctt tccgtttctt tgtttttggt
     8941 acttactctt tccttacgtt ctctttcaat atttactgat gctcggaaaa tgaaataatc
     9001 gcctgaaact tcatcttctt tttcaccaaa tttggctcgt ccgcttgttg ctcttgtcag
     9061 gatcgaccct aaatcttgaa tttgtcgtaa aactgtttct ctaactttct tcccttttgg
     9121 ttgcgggatt tttacgatat attctcgaat atcttcattg acacttagat cacgtcttgt
     9181 atgaacagaa attttgatat ttttaagcgt tgatagcaca tcggattcta attgcgtttt
     9241 gtttcgtttt ctttttttgt tgttcgtttc atctcctata atcttgtttg gatcatactt
     9301 cacatccata gcttctagag cttctctttt caaccttcta ctttccatat catcaaaaaa
     9361 tggtctttgt tctccatagt gatgcctgaa catcaaagta accaaatatc caacaaagaa
     9421 taccgttcct gcttctaata ctaaaataga gatgtctacc aagtgtagct ttgcaaaaaa
     9481 gctttgtaca ttatatgaat aacttaaata attgggaaaa aacgcattga gtaactcttt
     9541 aaacatttct tttaatccta aatcatctgt tccgttaaca tcatttaacg agacaagaat
     9601 acttactaag gtatctacaa gcagttgtac aacctttgtt acccaatgca aaatatatat
     9661 gccaattgca ccaactacca atgcacgtcc aaccagatat actgatttag aaaaactggc
     9721 tacaggataa tatttttctc catcgcttcg cttatattcc tttaattcaa tggatttttc
     9781 gctcatctga atatctcctt attttctttc tgattttggt tcatcgtcac ttatgctgtc
     9841 ctcacacatc tgcgtatctt taggaatgat tactctgatt tcgtctaaca tttctctctc
     9901 aatgatcatc gccccttttg tactaacagt tttctctgat aattcaacac atttccctat
     9961 ttcagaatct ggatcaaaaa tagcctgttc tacgtcaaaa tgattcttag ctacatacac
    10021 gatactcatt gtttctaact ctctagcaac tgaatattta cccttcttca gaagatagta
    10081 gccatttcct ttttttattc gatttgcaac tgatttatct aatccattga tgcttattat
    10141 ttccaattct tcaccttctc aatttctaat ctcttaccca agtaccattt tgatagttga
    10201 tgttgattcc tttttgattg ttaaatacat aaacattaag gtttaccgtt tttccattat
    10261 cgttaactga gaaagcttcg acatgagaac cacgaggaac caattcattc cctttataaa
    10321 ttggatcaac tttatacaat actttttcat tcttattttt atagattgca tcacgtacaa
    10381 tcgtttctga gtaagccatc cctccattct gatcattttt cccaacattt tgcgctctcg
    10441 ttccaagtgt taaattgtgt acctccatat ctcctcctag cgaccatgct aatgaatgac
    10501 ttttgttata gagataacct ttatatcctt ctagctgagt gatttcattg tttgaatctt
    10561 tgccgaccca agtatctctc tcttgatcaa atactccatc cttgtattct cctgcaatat
    10621 ggacagaact tttgaaagat ggacgttcca catttttaga tgagtgagaa tttacagcat
    10681 cataggtgat caacgcttca acatctcctg ctcttccaag ttgatctaaa tctgcataat
    10741 ttacccaaaa ggtttgactg cctttttctg ataatgcttc atggtcttct tttgtcagtg
    10801 tatatttccc atcattaatg tttacgatat tatttggata tttgtttgga tcataacgta
    10861 tccctaaaaa ttcttttgat tcactgtctg ctttattacc tacctgaaca ctacttttga
    10921 tctgaaaatc atgttcctga gtgctgttat tctgaaagta acccttgcca ctaagaccaa
    10981 ccgcaactaa aactaaaatt cctaacaacg atcgactaaa cttcttcttt ttcataccat
    11041 cattcctttt attgtgttat cataataaga taaatatata ataaactata ttgtaaattt
    11101 tgtcaaatgt atttttattt atccccacta taaaccttga tatatagcca atttaaaaaa
    11161 ggatggcaaa aaattatcaa gttaaaaaaa taaattttga accaaattat ttttaaaaaa
    11221 atagctagtt tttttatcaa aaaaaaaaga gcttttcagc tctattttat tcaatatcat
    11281 tttgatcaat taataatcgt acactccaat taaccgagtt ttgatcactc aaatatttat
    11341 aatctttgtc atcaaaaacc agttgccaaa ctctggtacg aacagtttct tcgtccactt
    11401 cctcatctga agagtattgc gataatgctt cttcaactat atactttaca acttcctcaa
    11461 aatcagtagg aactttatca ataaccactt catagtcttc ttgttttacg atattgggat
    11521 caatatgttc atccaaacat acctcagtga gtttttcttt cacctctgta tctctttctg
    11581 tttttaggta ctctgcatag tcttccttag accattgttt ttcaagatca tccgctatac
    11641 ttttaataaa ggattcttta tttaaccaat tatctgcggt atctatacct tcaaactcaa
    11701 aagctgttcc ttctatacgt gatttgacga aagcatcaat tttcttgtat tgattattca
    11761 tttcccatga aacacactca tcttcttgcg taatatcata aattttttcg gaaaaactaa
    11821 ctaattcatt ccacgatttc tcctcggcaa attgacttag tttcgatgcg ataaaaggaa
    11881 attttgcttt taagtcatcc atattcttga tctcaaattc gatattttct tctcctacag
    11941 ctgaaatcca tgctgaaaga ttgattgcaa tatcgctaaa gtcttctaca ttttcgacat
    12001 ttcctgtatt atcttttatt actgcttcta aagccatatc ggttgttgca ctcatggttt
    12061 gatctcctct cataatagag caaaaagccg gtttaaccgg ctttttgcat ggtacgtttt
    12121 gtttggtagt tttctgcttg tgtttatgtt gaaataatcc ctatagctct tcttttaata
    12181 gttcttcaac tttatctctt aactctccct gaccactctc taatagattt aaatagctca
    12241 tcagaatatc cgtttcatac gtttttaatt cagctctata ctcactttct gaatatgatc
    12301 gtaaataccc atcattgcta aatgcaacta gatcatcttg aaagttccat tctcctaaat
    12361 ttgttttact cactgcttcc catggactat tactaaacat ttcattaaag aaatcttcgt
    12421 cgttttgata taccttcaat tcaggaaaat agttgctgtc ttcattgatt tcttgcacca
    12481 tttttccaag ttcttcttca gataatttac cttccaataa ttttactttt tctctgtcat
    12541 ctgcataagc catttgaacc tctccttttt ctttttcaat ttcttcaggt gtttgttttg
    12601 gcgtaacttt caaatctatt ccattgccta ttagacccat tagataacca tagaacgttt
    12661 taaagtcact tgtagcaaga gatttggcat cagggtatgt atcccctcca attttatcta
    12721 aaacaaaatc agcaatcgtt acccaaggag aatatatcgt acacactaca tcccatgtag
    12781 catcttcaat attcgtccat gtcggaaagt cattttcatt caaatagtct tttttcagtg
    12841 tttcgatcag agtttttcca ctttcgtttt ggcttagata ttcaacaaat tctgcaccat
    12901 caaacctgct actaaatagt ttagctaatg agtctaaagt tgtttttgat atttccacca
    12961 ttactacacc tcctattaat attttacgat gacttgtttt tcattcacaa ataagatttt
    13021 ctacatctta tctattgctt tatagctttt ccatacatta tttctaaata caaccaataa
    13081 ccctattaaa ttaagctttt gagtttatct tttctaataa tattctgata aatattctga
    13141 taaaaaaatt tgttgtattt ttttcttgac tttttctttg gaattaagat cagttttgat
    13201 tttatttaaa agtgaatcta gctctattca aaataaaaaa gagatcaata atagtatcaa
    13261 tcccttttta ctgtactcta tcaattttta taatcttcat tatgcttttc taaactcttt
    13321 gattaaaaga ataagaacct ttagacttgc taatgctcct aatacagtcc aaatgactaa
    13381 aagcattttc tgatgtttat tggtaattcc tgtaaatatt gaacttgcct tttcagcaaa
    13441 cgttctgtct tgcatctcta cgctaccttg ttccggaata ttaagatcat tatttccatc
    13501 taattccttg ttggcacgat caacatcctc aaataaatca ttagaagatg taacagtttc
    13561 tggcttatct gaaacggatt cactatcaat ggcatcagcg tatgcggtat tgccaactgt
    13621 tacttgtggc gtgatgtatt ttgctttttc atctcttaga cttctaacta ataaacgatc
    13681 gtagttctga ggatatggat gacaagtata aagtgttaac atatctaaat caggaatatc
    13741 agtcagtgtt gaattctgac cgtaatttct aataacgtct gttcggaaaa ccgtataaac
    13801 tgctttttca ccaagataat ctatataaat gtggtctccg gctactaatt gatcaacata
    13861 aagaaattgt ggtgacgtat aaccgccacg atgacctgct attactgttt gatgaccttt
    13921 acctgataaa ggtagactag tagcactcat ttgtgccaca cctctatata aatgctcctg
    13981 tgaagcgcct agaaacaaaa gctctagcac atttattttt ggaatataga cataaccaac
    14041 cgctcctgaa taggtagatg gttcaaaatc tttcgtttga ttttttgaaa aaacatctcc
    14101 tgtgtatgga ttgacctttc cttcagcttc acgaatatca aatgatccac cgtctgtttc
    14161 ctgagtattg tctactcctt tatctgtttt ctgagtattg tctaatcctt ggttaccgct
    14221 gttcgatttt atttgttcga ctttttttgc cacttcctct tttgaaggag tttgtttttt
    14281 ctcaattttc tcttggattt ccgccacatt ctcttttgtt ttgaattgat gatagagctg
    14341 atttgcagga taaattgtta aaaccaaagt gcaaataaga gtcaaaaaaa gtagtatttt
    14401 attcttcatt tttcattcct cgtctctttg ctactatttt tttaataatg actatcacag
    14461 ctattattaa taaaacccct acaactacga taggatacca gttcatctgc gcctttacct
    14521 ttaaatcttc tttcttcttt tctttctcaa caatactttt ttggtaaggt atgctaaccc
    14581 ctctaacgag taacctatga gaattatctc caacaggtgt acatgtcata agtgttacat
    14641 aatcttttcc tgccacagga agcaaatcct caaattcggt tggtagaatt gtttttatcc
    14701 gatctacttg ataagcaagt tttttccctg aaatatcaat aaaaaattta tcaccaagtt
    14761 tgagcaactc taaatctgta aaatattttt tattaggaat gcctgaatga gctgatataa
    14821 cagaatggtt tccaatccca ccagttggat aatcagttcc ggttaatatt cctgctcctg
    14881 ctgatagttg aaaatcgttt acgccatcat aaattggcaa atccacatta atctttggta
    14941 taagaatttc acccactaat tcacctaatt tatccttctg aagatttcca tttgaaggaa
    15001 tattgttatt atcttcagga atcgtgactg aggtttgttc tgtgtctttt cgtttcctat
    15061 taacttctga atatcttttg aagacttctt cattctcctt ttcagaagct tcatcatatt
    15121 tttccttata ggagtttagt gtttgttgag tttggtagta ggtataagcc tgagtaatta
    15181 caggatatag acctactcct aaacatagca acatcccaat ttttaagatg atcaacttga
    15241 tattcttctt tttcatgctc atacctactt ttcacacact ttttaaaaag aaaccctaga
    15301 gccaaaaaca ctctagggaa ttttatttca ttaagctttg tgttgttctc gtttgtagac
    15361 aacatatagc cctgttcctg ccacacctgc aaccactaga aatactactg ttccaattcc
    15421 acctgtacga actgtttcag gtgttttaag gttcttgatg tctgttactt cgctagaagc
    15481 atcatcattc gataccacaa atggaacatc gtttctagtt ggtgtatatc ctgaaggagc
    15541 aacaacttct tcaagagcat aatcattgat ttttttatct gtgattgttg gattaccttg
    15601 tttatcaaaa tctacatcat aggtatattg caaaccttca atttggaact taccgtctga
    15661 tccggaaacg aattcagtag ctttagattt atctgcaatc caagtaacag ctttcgttgt
    15721 tggatcttgt tttaggtaag taactttatt cggatcaatt ttgttcttca ctacaaattt
    15781 tgctccactc aatgctttgc ttgtatctcc atctgtttta atgaattggt gatcaccaat
    15841 gattgtataa gcgtgatcaa ctggtgtttc gtcttcgggt tcatatccat tgttgtagat
    15901 cgttgaaaca tcattcttaa gtggtgtatc cattttagct ttactattag tatgagcgtt
    15961 catcaaaatt gtaaagaagc gatcccctgc atcaaattgt ttctgaagct tatccatacc
    16021 tgattcagta aagacatagt ttgtcgtttg tccgtcacgt tcgatactgt aatcagtatc
    16081 taaagtcatt ccttcgatca cttctgatga atcataagtt aactctgcac ctagaacatc
    16141 tttgacaaca tatttttcgt aattaccaat attaccagga attgatggtt tcaatgtata
    16201 ttgaacatct tcgccagtat caacggtttc tttatcaatt accttagtaa ttacaggtcg
    16261 tttgtagttg gtaacatcaa gaactacttt agcagtctcc ccacgtttaa cgctaaattt
    16321 gaatttttta ccatctagta aataggttgt tctattagca tctgttccca aatcggtttc
    16381 taggaaataa tagtcaccta attccaaacc atccacagtt aatttacctg tgctgtctgt
    16441 tttataagtt ccaacaacct gatcagatcc atcatctttt cgcaattcaa aaacagttcc
    16501 ggcaagagcc tttccatctt cgtctttttt atcaagctct gctgagttta attggaaata
    16561 gtttttagga tagacatgta catcataatt aaagtattga tcatctgatc cgtttagttc
    16621 aggtacgtta acaatcatag gatacgcttc ttcaactaca cctttgactg ttcctgtttc
    16681 aacaatcaaa tacaagttat ctgttaaatc gtctgtattt acttgtatag gtatgtctat
    16741 attcccttgt gaatcagtct tcattctact tacttcactg tattttttgt ttagtaataa
    16801 tcgtgcttta gcatcatcaa tatgttgacc ttttgtagta tcactatccg tccatcccaa
    16861 ggatttagct tcatctttag taagtttcac ataagagaac tcaacgcctt caagaggttt
    16921 tacaccattt ggtaaagcta tttctttccc tttgttatca atatctgaga cagggttccc
    16981 atccccatta gtatttgtta ctttatggat atgaatcgtt ccagttcctt gataattata
    17041 gttttgttgt gcatatgcta cttgcccccc tagtccaagg ctagaagaga ttgagcttgc
    17101 gcccaatccc actcctagca aagtaccaaa tagcattaaa tttgaaaaaa ttttttttga
    17161 tttcatacgt cagccttctt ttttcatatt tacttctttt ccattaacac ttttttattt
    17221 tgctttgtgc tgttctcgat aatacagtag caccatactc aatcctgcaa ttagaaatac
    17281 aagaaggaag gctgatgtac cgattccgcc tgttcttact gtttcaggta caaggtgatt
    17341 aattactgta tattcaaagg tttgtccatc gtcagcaacg gtgatgcctt ctttagacca
    17401 tttccctgta taaccattag ggttttgtgt ttcttcgatt ttgtacgttt tgttggcaac
    17461 aatattaaat gttgccaagc catttctgtc cgttttttgt acaactttta cacctttgtc
    17521 gtccgtcaaa gtgaattctg cgtttgctaa tgctttccct tgatcatcga ctttatgaac
    17581 tttgatcaca ccttttttca aagtgttttt agctgtatat tcaaagactt gtccatcatc
    17641 tttgacggta attccttctt gtttgaatgc gcctgtgtaa cctgttggta cttttgtttc
    17701 ttctaagttg taagttttgt tcgcaataat gttgaacgta gccagaccag ttgcatccgt
    17761 ctttttaact tcttttacac ctttttcatc cgttaaggtg aattctgcat ctgctaaagg
    17821 ttttccatct tgatcgactt tatgaacttt tactacacct tttttcaaag tgtttgtagc
    17881 tgtatattca aaagtttgcc catcgtcttt aacactgata ccctcttgct taaatgcacc
    17941 tgtgtaacct actggtactc cggtttcttc tagactatac gtcttgtttg ctacaatatt
    18001 gaagcttgca agtccatttt catctgtttt ttctacttgt gttgcacctt tttcatcggt
    18061 taaagtgaac tctgcatttg ccaaaggttt tccatcttga tcgactttat gaacttttac
    18121 tacacctttt ttcaaagtgt ttgtagctgt atattcaaaa gtttgtccat catctttaac
    18181 ggtaattcct tcttgcttga atgcgcctgt ataaccagtt ggtactccgg tctcttcaag
    18241 gctgtaggtc ttgtttgcta caatatcgaa gcttgcaagt ccgttttcat ctgttttttc
    18301 tgcttgtgtt tgggatgaat catccgtcaa ggtaaattca gcattagcta atggttttcc
    18361 atcttggtca acctttttaa cttttacttt acctttttta attgtgttcg tagcagtgta
    18421 actaaatttt tgtccatcgg tattaacagt aataccatcc tttttaaatg aaccttgata
    18481 accttcagga acttttgttt cttctaagct gtatgttaag ccttgttgca aatcaaacgt
    18541 agctaaccca tcatctccgg ttgtcttaac agatttagca ttgttattgt cagttagagt
    18601 gaactccgct ccttttaaag catttccatc ttgatcaact ttcttaactg ttacctgacc
    18661 aacagctctt gtccatttag cactcaaaga tttagagtcc tttgtttctg aagtagtgat
    18721 cataactacg gcatcttgat acacgcctcg tccatcaaaa gtaaaaggat tggttgtgct
    18781 aacattagca gtacctttaa atgacaaagt accacttggt gtagtcacag gtactttaat
    18841 agtaaaactt gaatttaatt tcacagtgtt gttagtaatt tctttaccat ctgcatcata
    18901 aatcttcata ccagctggtt ttgctgatgt aaaagtgagc ttcgcattac cagtcttatt
    18961 tgatgctgtt ttatatgtga aagtgtgata ttttccttcg tcagctgtct tagaagctgt
    19021 gatagaaaac tcagtgttgg gcgtatcttt tccattctta gcatagtcat aaattttttc
    19081 aaatgctttt tttacacgag ctgtttctgc ggcggtatgg tttggatgtg accatacaat
    19141 ctgtgaaact ttaaagtttc cggctaaaac ccatgaaact aattgtgttg cataccatgc
    19201 ttctgtatca tttcctgcac ccagttcctt tgctgttttt gatggaaaac cacctttaaa
    19261 catacgatag aactcatcac tgccagctcc cttgtacttc aagcttccgg ctccacttcc
    19321 tgttggggat ggcaattctg aatccataca atatccaata tttccatgag aatctttaaa
    19381 ttgacttgaa atcatccatt catttggatg attcggcata ttaaccctaa tataaccgtc
    19441 tgtttttacg ccagtttctg taaattttgc acttgtcggt tttgtgacat ctgcttcagc
    19501 tcttattgct gaaaaaggca ttataagcgt agataacacc attactaaag tcgcaaaaca
    19561 ataaattatt tttgatttta aaattatcgt tttttcatgc ttcatctctc gttactcctt
    19621 ctttatacca gttaggcgaa gaaaatgagc cacgatatgt cggtgtggta atgaccttcg
    19681 cgcccattcc taagttaaaa tcaccacacc tattaatcac ttttttcgtt gaaagcaagc
    19741 tgtttcaacg ctctagtatt catagcatca ccccttttag ttctacccac catgagcaac
    19801 aagttttcta agtagttaag caaggacaaa taaagactat acttaactac ttagtatata
    19861 aacaatctct tttattaacg taccgaaacc gctaattgag atacgttata tgctgtttca
    19921 aatgatcctg cattaatcca acttgcccca aacacaggat cgacaacatg gtaaaaaccg
    19981 tctttaaatc catcaacggc tactacatgt cgattccaaa tagcatcgcc ccaaaacatt
    20041 gatttatgtt gagcaggttc aaaggcataa gttacccacg ctactacagg atttccattt
    20101 acaatctcat cttttaatcc ttgtaccgat gaaccagaaa tatctacaac atttccgcca
    20161 ttagcaacac cccatgaaac tacaggagcc ggattcatac cttgataagt tccatccaca
    20221 ttgtgtctcc attcaccaga aaaaccatta tttggattat tatcaggaga tagtggcatt
    20281 gatttaacaa aagtcattaa atcttgattt gttgcaacac ctttataatg taacgcttct
    20341 agcaaagatg ttccttcgca aagcattgtg ttaccttgac taataaatgg aacgcctagc
    20401 acaacattag ttggttgttc gggtttactt ggtgaagtag aactgtcagt ttcatcactc
    20461 gaacctgttt gtgattgatc actagaagat gtactggttg attcatttgc atcatttgat
    20521 gttgattgtg agttatttgt tgatgttcca gtatcagttt ccgtagtgct actttcactt
    20581 gttccctgtg atgcttcttt ctcacttgta gaattatttg tattagatga acttgctcca
    20641 tcaacacttg aagcacttgt ttctgtctta tcagaagtgt ttgctgttgg ttccgattct
    20701 tttgcagtct cggatttttt gttctcttgc tccgtatttt caacaggatc aggtttatct
    20761 ttttgaacag tttgactaac tacttcgcca tctgcttcct taactgttaa tgtatcttta
    20821 ctgatgttga aagttcgtcc aattgggata gtccgttgtt ctccttttgc caaatcaaca
    20881 ttgttcaatt cggcaaactc agcaacagta gtcttgtaac ctaagctttt aagcttctct
    20941 acagttgacc aaatagtatc tccttttttg aacgcataac ttgattgtcc tgttgtaatt
    21001 tggatttgat ccggtgtgtt tgcagtccat tcatcagcat gtgaggttac tggtactgat
    21061 aaccccgcaa gtacagctga tgcaaataaa accataccaa gcgaattttt cttcatattc
    21121 attccttctt tttgttttta ttttctgttt gtgatcgcaa tgcttctatt ccttcttccg
    21181 ttataatata ggttttgtca cccactttct tgaacgaacc tttaggcaaa cgatttggat
    21241 aatagttgat tatgtttgta acataatttc tacctttacc caaaatcaaa cttgcttccc
    21301 ttgcggtgta caagttgtat ttgtctaggt tcaatttctt tttgtttgcg atttagacct
    21361 acccctttcg caaaatttat tgtataataa tagtaccatt gcactgtcat aattgcaata
    21421 tttttttggg gtttatcctc atttaatagc ctaaaaaggc ttgttagata aggaatatct
    21481 aactaatcaa aacaaaaagg aagttaagaa aaaatgaaca aaaaaaggaa attatcagta
    21541 ttaattacac ttgtttctat attgactatt cttagcggta tcttgtcgct gaaaatattc
    21601 aatcaaataa acacaagctc aaatgccaaa gatggaatag tcgtagaaaa tacctctaat
    21661 tctaaagaaa ctgttactac tacaaaaaaa gacaaatctg ctgagatcac tacgaaaaat
    21721 tatttaataa agactgttta ttttgatgaa cgaaaaacag caattctcaa agatgaggaa
    21781 ggatcagaat taaagctacc tataacggta tccgataagt tcaacggaac gttctcctta
    21841 caaaccgctg aaggatcacc tgacaatctc aaagttgggc aaacaatcat tcttggtaaa
    21901 aacgacgaac tgtattcatt tgtaaaataa aaaaatagag acgatcaaaa gatcatctct
    21961 aaaactccgg cagtaggact cgaacctacg acatcatgat taacagtcat gcgctactac
    22021 caactgagct atgccggaag aatactttac tataatatca atttttattt catgatgcaa
    22081 tcctaatttt caaaaattag atggaactgc tgaaaatttt tatcgaaata aaaatggaac
    22141 gatttcaaat agaattagag gatttattat gtcaaaacac aagcaccaaa aaagaaagaa
    22201 aaataaatta acacttgttt ttccgctttt tttaatactc ctagcattca gcggaatgta
    22261 tgctgaacac agctatcctg agcatcacgc aacgaaaaaa agcagcacac ctgcaacgaa
    22321 aacaactact gatttgacca atcagcaacc aatcgaacca aaaaatgcta cgtccgctgg
    22381 tattgagcag ttattggtag aaaaaaattt tagcggtact gttttagttt ttcagcatgg
    22441 acaggtgatt ttgaataaag cttatggctg gaaagatcaa gctagaagaa tccacaatac
    22501 gattcataca caatattgca tcggctccgt tcaaaaggga caaactgcct atttgatcat
    22561 gcaggcggtt aaatctggta aaatttccct agaggaaaag ctcagcacct tttatccgca
    22621 aatttctaat agtgagaaaa tctctatcaa agatatgctg aatatgagtt ctgggttacg
    22681 tatcgacgaa aagaaaattg ccgccttgaa cactactgat ccacaaaaaa tactttcaga
    22741 gacaattcgt caaacgactg tggctgcgaa ttctagttac tcctatcaac cggtcaatta
    22801 tgttttgtta gctggaattt tggagcaagt ctatcatacc gactacagca cactatttga
    22861 taaactttta agaaaaccaa tgaagctgaa agaaacaagc ttctattcag aaacgaacaa
    22921 tcagcaggct ctttcatact cagaaagttc ctccggccct gtttacgctc ctacgaccgt
    22981 atcttcttac gcagatgaat taggaacagg caatgtgttt atgtcggggg aggatttgta
    23041 cagctatttt caagatcttt atcaggacaa atttttaaca acacaagaac gtgctgcatt
    23101 atggcaatcg tatccaggtg aaaaatacgc cagcggaatc tataacatga caaataacta
    23161 ccattcacga ggagttaagg cacgttttga agcccttgtt gatttttcaa aagatggtca
    23221 aaatggcatt attctgctct caaatgtctg gactcaacca aagggatata atgatatcgt
    23281 ctctaaacta tataaacaag tcgtcgcagg ctcgtaagcg acgactcgtt tataaataaa
    23341 gaattcacag cagctaatgc cgcatttttt tctgtttaac cagttgacaa ataagcttgt
    23401 tttcgctatt ctatatcttg tgttaaataa ctatgccgcc ttagctcagc tggtagagcg
    23461 tttccatggt aaggaagagg tcgtcggttc aagcccgaca ggtggctctt ctaagaacgt
    23521 tgagttttca acgttctttt ttttgtttag aactactttc aattcctgca aggtagcagc
    23581 tggcaagtgt cagacctaat aaaattccac caaaaatatc ggttccccaa tgggctccag
    23641 acaaaaaacg tccgataacc agcgcaatca tgaccaccag gctcacatag gcgatgattg
    23701 cttttcccgt tcctgtttcc tttcttaata cataaaaagc tgacagtaag actgtaattg
    23761 ccagaaaagt atgacttgac ggataggatg cctctagctg tccatccact aaaatcggtc
    23821 gataattgat gatgactttt tcaaaaagaa catagcaagc ggcgactcca gcataaagaa
    23881 atcctagcgc aagaatttcc ttgtccacta gtaagagctt cttgcgggta tacaattgga
    23941 aaaatcctcg taaagcaaaa taccccacga ttatcaatgg aaaaatccct aagatttccg
    24001 tcacttgata ccaaaattca ctagtaccta tcttctgaaa tacgtattga ttaattgtag
    24061 aaaagcccac ctccgaatgc tgcggaccta ttttctgtac atcgaacaag gataaagaaa
    24121 tcgtgtataa aataaagacg atcaataatc ctatggctgt ttctaattgc ttctttgcta
    24181 ttttcatttg actaatcctc tcctaacaat tatttggaag ctatccaaat aaaacgtatc
    24241 agagactgcc agaaacaaaa agaagcgcac cgtcaccttg atgtgacgat gcgtatcaac
    24301 ggctatttaa tagggaaatc cccttcactg ccaaaagcat taatacatac gttgccgggt
    24361 atggatgtct agtcatgatg aaaagcagta cgccgaacaa cgataaaatc aaagaaaccg
    24421 atccaataat tcgttgttct cgcctagaaa aagcgagttc aaaaatgccg aacagcattg
    24481 ttaaaataac gaatgaaaaa ataataagct tgaagataat tgtttcctgc gaaagttgcc
    24541 ataaagagac aaacgcaata tggttccctt gtgcttgacc aaaaatcggc agaacaatta
    24601 ataagccgac catgcaatct gaaataccta aaagcaaatg ttgaaagttt ttccgctgct
    24661 gttgctgctc attttctgca attgacagca attcactatt ggatagcaac tcatcaatag
    24721 aaatatcaaa aacctgcgaa atagctttta aggaatcaat actgggaaac ccgcgacctg
    24781 actcccattt ggaaactgct gttcgtgaga taaatagtct ctctgctaat tcttcctgcg
    24841 tccattgctt attttgacgt aattgcttta gtttctcgtt gaaatccact ctaatctccc
    24901 attctttctt ttctcctcaa tcataccata atagcagaac agaaaaagga gctggttcga
    24961 aagtctttta gactttcaaa ctagctccta ttcacaaata aacgacgcct ctatatcatc
    25021 ttctatgaga ttttactcgt cctcgtcatc atcgtcaccg atgatccgtt cattcacgtg
    25081 gcaaatatta cttgtcgcag attcgactaa tgcaagctct gtaccgatca attcactatt
    25141 gatgaaatca atcaccatcg gcatattcat tcctgcgtat agttcgatcg cttgcccttc
    25201 taaaatcatc cgcgagacta cattacaagg tgtcccgccc attaaatcag ccagcacgac
    25261 aaaatcatct aaatccgcaa taactgcttc aaattttgcg cgaaaatctt ccgctgactc
    25321 tgcgggaagt aaactgactg tatggatgct ttcttgcggt cccataatca tttccgtact
    25381 ctttttcaat tcctcacaaa agagtccatg actcactaaa actaattgtt ttcccattgg
    25441 ttcgctcctc attattcatt ggaatcagcc taacttattt agaaatcaca cctaatgctg
    25501 ataatgccac acagactact aatacgataa agatcgcctt ggttgaagtc atgttctttt
    25561 tacctagcat ccaataaatc gctgcaacga ttcctgctgg taataagcgc ggtaagatca
    25621 tatcaagatt gttctgcata ttcaacgtca catcaccaat gctcggtgcc caagagaatt
    25681 ttacattgat catggtggca actaacgccc caaccatgaa gaccccaagc aaagtcgccg
    25741 cgtctgtcaa agcagttaag cgatgctgca tcgttgtaac taaagagatt ccttcacgat
    25801 aagcgaattc cagttgtttc caacggaaga tcattaccgc gatttgtgcg atgatccaaa
    25861 tgaagatacc agttggattt ccattgatcg ccatattcgc tgccaaggcc ccaaaaatcg
    25921 ttggaatcaa tgcggcgaag atcgaatccc caattgccgc aaagggaccc attaacccag
    25981 ccttcatccc tgatacagtg tcttttccgc cgatcccttc tttttcttca atcgccaagt
    26041 caatcccagt cacgattgta ttgaagaagt ttgacgtatt aaaaaattgt gtatgagtct
    26101 tcataatttc ttttaactcc ggcgtgtcat cgccataaat cttacgtaat tgcggcaaga
    26161 ttgtataaag atagcctgat ccttgcatcc gttcatagtt ccagcctaat tggaaggtaa
    26221 acaagcttct gcgattgatc tgcttaaaat cttccttcgt caacttataa ttagatttcg
    26281 tcatcttcaa tctctccttc atctgaatca ttggaagcaa cttctttcgg tgctggggaa
    26341 cttggaatca tctgtccatt cttataactg atcgcagcta aagcaaatcc gatcaatgcg
    26401 atggctaaca taggaagtga attgaaaatg ccttcgaaat tcttcacaac acccgcaaca
    26461 ccagtgccta aaacctgcat attcgtaaag actgttccta gtaacgctgt taacgtgaac
    26521 cctaggatca agtaaggaaa gtgttttttc acaggcaagt aacgtaataa aatcgcaaac
    26581 ccgacagctg gtaaaactgc tccggctaca gatagaccgt cacctaacca tttcaaatca
    26641 ccattcaaga cagcaacaac cttttcgact aagcctccgc caaatgctaa cgctaaaaag
    26701 actggaatca tgcgagaaaa tgaccatgga atggccccca tcaagaagtt gcgttcaatg
    26761 cctttataat tcatatcttc gactaattta tcaatccgat gagcgaaata cgtattggca
    26821 aaacgagcca aaatatctaa ttgaatcatc aagctggcaa ctggtaccgc aattgcagcg
    26881 atcgcttgct ctggattcat tcccaatgct actgaaaaag ctgttgctag aatcgttccg
    26941 gagttagcgt caatttttga tgcgcctcca aatgtaccga cacctagtac ggtcaattgc
    27001 atactaccgc caataataag tcctgctttt aaatcgccca ttactaggcc ggcaaataat
    27061 ccggcaaaga ctggtgcact caatgatgaa taaatttgta attcatctaa aatttgatac
    27121 cctgcatata atgttaataa taagatctgc caccataaga tatccattta cttatcctcc
    27181 tatttcgcta atagattcat gaagtcttct gctttatcac ttggtaccat ttgtgcgatc
    27241 aatcgaacgc ctttagcatg taattggttg aatacttcta catcctgatc gacaacattg
    27301 attgatttag taattgaacg cgtttcatct gtttgcgaca tatttccaac attgatttct
    27361 tcaattggaa cacctaactc aactagcttc aataaacgat cgggtttgcg ggcaatgatc
    27421 aatagacgtt gagaatcata tttccctgct aagatattgt tagcggcttt ttcaatcggc
    27481 agcacgctta gcttcacgcc tgctggagta gccagcttca gtccgctttt ttcaatatca
    27541 ttttgtgcca cttcatcatc taccaccatg atccgcgtaa tattcagttt tgttgtccat
    27601 aagtttgcta cctgtccgtg aattaaacgt ccgtcaattc ttactccaat aatactcatt
    27661 gttatccctc tttcatttct ttatataatg gtttttttac caattgaatc tctggttgaa
    27721 aggttccttc tgtttcaaaa atcacgattt cattgttgcc ttctttaagt aatcccttag
    27781 gaatataaag cgatagtgtt gggccaactt cccaaaatcg tccgatattt acttgattga
    27841 caaaaacgac accttttcca aaattcgaca gatcgataaa gctgtcttcc acttcatcaa
    27901 gcactacttc atagcgataa aaacttggct gctctggctg ccattctctt gaataatcaa
    27961 ctgcctcaca agaatccagc ggcaagcaat actgcgacca atcagtgagg aaatgcagat
    28021 cagccataac tcctgttcga atccccttat tttgtgtatc agcaaataat ttgtgtccgt
    28081 aattaacccg ccccatattt tcaatcaaaa tgtctaattg attggtttct tcagtcatcg
    28141 gaacaatgat atcctcgccg atttgcgtct gatactgtgt cgcttgtaat ttttgattta
    28201 gaaatagctg actacgatcg cgaccatcaa tgactctcag tctttcttct tccgcgtcct
    28261 ttttaatcga tgtgcgatac agaatgtagc cagtattttg tcctagcatt tccatcgtct
    28321 ctggatatgt cgttttcacc ggttgactga tcgtgtctaa agttgaaaac aagctgactt
    28381 tatttcttaa atgaattcct tttacttcca ttgtgttctt tgtcaacggt tccatttgtt
    28441 gaatctcagg aaacgtatca tgaatcattt tttgaattgc gaaatatttt tcggttggat
    28501 tgccctgctc atttagcgga gccccgtaat cataagaagt aatttgcggc aaatcaatga
    28561 ctcctcgtgc ggagcagcca ttcataaaac caaaattcgt tcccccatga aacatatata
    28621 gattgatact gcctctaatt aagacttcct taactgcttc cgccaactcc tcggcatctc
    28681 gttgaacaat aggttccttc cagcgattga accagccatc ccaaaattcc atgcacatca
    28741 ggggccactt ttttccgtgt tcatcgaaga aactctgcat ggatgcaaaa ttctcttcgg
    28801 cctttgaacc aaaattgccc gtaactaaaa tatcttcttc tatcatgctg cctgctctaa
    28861 gtgtcgcacg ccaaggccca tctgaagtga aaaacggaac cgtgattcct ctgtttatca
    28921 tcaaatctcg aaccgaacgt aaatagtctt tttcttctcc atatgaacca tattcattct
    28981 cgatttggat catcaaaata tttccgccat ttgacaactg atgaggaacc agtttcttta
    29041 tgaggacatc ataataatca gccacatgtt ttaaataacc gatttcattt gttcggatgc
    29101 gtgtgtcttc gtttagtagc caagcgggga atccaccaaa ctcccattct gcacaaatgt
    29161 atggtgatgg tcttacgatc gcatataact cgagttcctt tgcaattgat aaaaagcgtt
    29221 ccaaatctag tattccttca aaatggaact cacctttttt tggttcatgc aaattccatg
    29281 gtatatacgt ttcaacggta ttgaagccta aagctttcag gttatacagt gagtgatacc
    29341 aatccgctgg gtcaatccga aaataatgta ttgctcctga catgatctta aaggcctcgc
    29401 cgtttaaaag aaaatcttct ttaatctcaa atgttttcaa aagctccctc cttaaatgaa
    29461 agcgttttta atatattaat atattaaatt attcgatact gaaagtcaac tctccttatt
    29521 ttagtggaat gtgttaaaat caagccataa ccacaaaatc aaaaaattct aatgaaactt
    29581 ttaattccta ttcattgttt ggaggttcct atggtcatcc caaaatacca aatcataaaa
    29641 gatgaactaa aacagcaaat catttctggc aaattcgaaa atggcgacaa attttatacg
    29701 gaagccgagt tggcagaaat gttcagtgtc agctcaatca ccgtcattcg cgcgttgaat
    29761 gatttagtca aggatggatt cattgttcga catcaaggcc gcggttcttt cgtctcgcgc
    29821 gcccgtaaag gaaaaatagt cgaattttcc gatatcgagt tgtttcctat aagtaatgat
    29881 caagtacaag tcttatcaat cacacgagga aatgatcccg tttatttaag taagctcgaa
    29941 ttgcctgata cagcatttta ttactgcatc aaacgcttgc gcaaagccga agaaactccg
    30001 tatatctatc aacagaccta tttgccggaa caatatgtga atcctaatta tcaagaactg
    30061 agctattaca attccatcta tcaacgcttt aagctagatt ataatatcca tatgaacgaa
    30121 gaagacttta ccgaaacaaa tgaaatcaag ttcccgactc cttcagatgc agcaaagctg
    30181 ctggagattt ctgctgatga accaactgtt ctccaagtcc gtgtgaccaa acgaagggat
    30241 acacagcaaa tgctggaata tgttgaatcc tataaaaaat ggaattttta caaaattgaa
    30301 ctggtctcaa aaaacaatta atcctgacta gatcgagctt attgctcgat cttttttact
    30361 atgaaaaaag tataaaattt tcacatgaat aaatcgtttt acagcaggca tatccatgtc
    30421 cggcttcacg aactagcttt ttcggcaata agcaaaaata tttcgaaatt tgagaagcac
    30481 caagtaggta ccaatcaaca tcagttctct tcgatcactg tgtttcttgg caatttagaa
    30541 atattttggt cttattgctc aaaagctgag cgagttcgcg aagcctttct tacgttgatc
    30601 tcttcaaaat gcatgtccac attcgctaga ttgacatgac ctgttcgcac ttcttgagca
    30661 ttggccatac cggctgccat acaaagcttc agcagttctg ttacgctcat tttttgtgat
    30721 aagccatagg caaacccagc tatagtagca tcacctgacc ccactggatt aactgtttta
    30781 atcgttggaa tcgttactcg atagaaagaa tcacgatatt ttgcaagcgc cccatctttg
    30841 cctagtgaca caacaatcca ctcaacacca gtaaataaag gctgagctaa agctgactgc
    30901 agctcttcta agtcatcaat tgaaaacggc tgacccaata aagcttctag ctcttcaagg
    30961 tttggcttaa tcagaaaggg tttatgctca ccggttaaca cctgcctcag gctttcacca
    31021 gaggtatcca caaggacttt taccacttgt tcttccgcta attgaacgag cctttgataa
    31081 aaattcaatg ggagcccttt agccagactg cctgaaatgg tgacaatctc ggcttcttta
    31141 accaactcct gaaaattttc caaaaaagcc tgctgttccg cttctgaaac tgtcggacca
    31201 gcttctaata tttccgtctg atttccttca tgcaagatcg caattgaatc tcgactttcc
    31261 tcttggattt ctgtaaatgc ctgcttgata cctgctttct ttaattcttc cgagatataa
    31321 gcgccatgaa aaccgcctaa aacacccgtt gctaaaacat cgcccttcaa atcatgaatg
    31381 acacgcgtga cattaagtcc ttttccgcca gctgttttac tcacctgatc ggttcgattg
    31441 accgtgtcta gcttcagttt ctccagtgga taagaaatat caatggacgg gttcatcgtt
    31501 actgttacta tcacgagctc gcctcctagt tcaccgcttc ttcttctgcg acttgaactt
    31561 tgtcatgcca tgagcttgcc gtttgtttta acatgttgtt caagctttcg atattttcac
    31621 gaccttcgct ttgcagccag tcacgagcag cagcttcacc tgattcaata aacggcttta
    31681 caccattttt ccaggtggca cgcccacaga gcacaccatt gaaggtggag ccagcttctt
    31741 tagcaaatac caatgtttgt tggaatagct ccgttgaaac acctgcgctt aagaaaataa
    31801 atggtaaatc cgttgcttgg ctttgttcta agaaatagtt tgccgcttct tcttttgtat
    31861 aagcgatttc accagtacca aagccttcaa cgaaattcat attcactggg acctccactt
    31921 ttagaacatc cactttgtat tgcggttttg agaattcctt catcatatca ttgaccttgt
    31981 gcggtttcac tttggcatag tcaaatgaac cagcatctga aatttgcgca tcataagaaa
    32041 ccaattctaa gtaaaatggc aaatcttctt ctgcacattc actgcctaac cgttcgacaa
    32101 agacatgctt ttgatgattg atcgcaggat cttcatccac atcataataa agtaaaaact
    32161 tgatagcatc ggcaccttgt tcttttagtc gtaaaaccga ccaatccgct aatagatcag
    32221 gtaaacgtcc tggtgtggtt gcatcgtagc ctgttttttc atatgccagc aatagacctg
    32281 catctgcatg acgtactttt gctgcaggca gaccgtattc agggtccaat aagatcgaag
    32341 acgcatatgg tgtcagctcg ctcgatacca attctttaaa atgctcaata tgcttatccg
    32401 ttggttcgac atttaacgct ttgatcattt tttttaacgc cccacgttga tcaattgcta
    32461 aggcactgat aatgccatcc tttgttgata aacggtccat cgccgctttt ttacctgttg
    32521 ttaatgtaag catgtttctt cctcccagtt aattcctatt tatagtcatg aatcgttacg
    32581 ccttttacca ctcgattgac tgttcccgtt ggtgaaggcg tgtcaggtgt attcgcaact
    32641 ttcaccgatg ttaaaagcgc gacagtttgt gctaccatga catagcctag tgctaaatag
    32701 gcatctggaa gtaaagaagt cccagttgca aactcgaacg tatccccaga gaaattccgt
    32761 tttccgggtt gagtgatagc aaagacaccg gaagcgattt catcttcgtg aacttcttct
    32821 aagatatcta aatcgtaatc ccgcgtgtat ggatcattat tgacaaaacc gaacataata
    32881 gttttttcat tgataaatga ttttggtccg tgtctaaagc ccatcgatga atcaaagact
    32941 gtcgcgattt ttccagcggt cagttctagg atttttaatt gtgcttctct ggtcaagcct
    33001 gctaaactgc cggaaccgac ataaacaatt cgttcaaaat caagtgcgac aatttcttcg
    33061 atgtcatgct cacgggcgat cacttcgttt cctaaagcgt tcaatgtttc tacatagttt
    33121 tgcttttccg ctagtgctgt ttgatcaaat gtcagcaacg cgcctagtgt catacaggag
    33181 aagctgccag tcatggcaaa accgtcatca ttcgaacgaa caggcattaa gaataaaaag
    33241 ctcttggagt ctgcttggct gatttgcgcc aattttccct cttttgcaca ggtgattgat
    33301 aaatgatgga ttgtatccac gacttgattt gcgatttcaa ctgctgccaa gctttcagga
    33361 ctgtttccgc ttctggcaaa ggataccagt aaggtcggtt cctctttgat taaatattct
    33421 tcaggctccg ccacgatgtc agtggttccg atactttcaa agctgaaggc ttgacgatcg
    33481 ccgtgtttgc gcaaataagg aaccagcgtg tcgcctacat attgggaggt tcccgcaccg
    33541 gtgaaaatta cgcgtgtacg ctgacccttt gcttgttttt ggacttctgt aagaaaattt
    33601 tctaattccc cttgggctga ctgataaagg tcaatcgttt ctttccaaag ttccggctgt
    33661 tggcgaatct cacgcgtcgt gatctccgct cccatttgtt ccaatttttc tttttctatt
    33721 gtaaacatgc tttaattctc ctaactattt cgaatatgac gaatctgata atgaaattga
    33781 tccgcgcgag cgacgctcaa agtaaattca atgatttcat ttttcatatt gtaggtctga
    33841 cggactaaat gcaggactgg tgctccttca gggatcatca gctgtttcgc gtcatccttt
    33901 gaagcgatgc tggcataaag ctcttcatct gctaaacgga ccgtttgctt aaaatcttct
    33961 gaaaaaagat cgtacaaggg cttgcttctt aatagctgat catctaatga caagaagaat
    34021 ttgacaggca gatagctatc ttcaatcatt aaaggctctc gatccgcgat ccgcagccga
    34081 ctcaatttga aaactgcttc tcctaaagga agattgagtc gttgtgcgat aaatttatca
    34141 gcttccattt tttcaaagga taaaattcgc gtctcaggat gtctgccgag gcttttcatt
    34201 tgttcggtaa agctgtaggc accagctaaa tctgcagcag ctgttttgat atcagagaca
    34261 aatgtccctt ttccatgacg ccgataaatg tatcccgtgt tttccagctc ttgcaaagct
    34321 aaacggaccg tcgtccgact aactccgtac tgagctgtta attcccgctc agatggcagc
    34381 ttatcatgag gaatcatgcc gctttccatc cgcttcttca ataaatctac aagttgatga
    34441 tacaaagctt tgtttttaaa agaattttcc atgggcttct ccttctttta aactggttat
    34501 aaccacaacc caatggtaag gtggtttttt tacctttgtc aacaataaat cttttagtaa
    34561 ttttactatc ggcttaaaat gctgatttat caagttttcg taagataaaa tatgctagta
    34621 aaatttttct ttcatactat attcaaatag acttttcaat aattggtatg aaaatctaat
    34681 accagttgac gcaattagag cataagaaaa ccaccggaga attcattctc cggtggactt
    34741 tttgtatgat taaccttctt attgaagatc actgatctta aactctattc caagggcatt
    34801 tctataatat tccggataca tctccttccc acatttttca caggtaaatt ggggaggatt
    34861 gttcggatca tttgcaatat ctgcatcatc taaaaatttt actacatcca ttgggattga
    34921 ttctttttca ccacaactta gacatataaa tttcacgttg gcgtccccaa tcccagcgaa
    34981 ttgctttaaa agttttttct ttttcttctt catactgttt cctgaattct ttttggtcaa
    35041 tttttcgatt ctcctctcgc ataaatcgct ttgcatggtt atctttcgca tatttaataa
    35101 ctaaccttcc atttttgcgc acactcatcc caacgaattc atagtactca ccgcaacaag
    35161 aacattctaa gggattttca ccaaattctt cggttattct ttcttcccag gattttggtc
    35221 ttaaggcctc attcagattg ataaacagct tttttactcg tttctgatac tccttcatga
    35281 cctttttcat taatgttttg attctacgac tatagattcc atagcgacga atcgttttga
    35341 aattcttatt ttgaatatgg cgaatcagtg cagctatgaa ttcgtctata ctcatggtca
    35401 tcgtctcttt agtattcgtt cgtttgtcca tatagttgaa catgacagtg tcgccatcat
    35461 acattaagat tcggcttaat gcgatcgggc cacgcttcat ataacgactg atgtattgga
    35521 gtagtgactt tagatttgtc ctgcttcttt taggagcatt tacgtaaaac ccttctccat
    35581 tgttcttgta cgcagcttgt aatcttgatt gaactctttg cttgtcccac tcacctaacg
    35641 ttcgtctaat tagtttcaat acagcatttt tccagtattt tcttaacata gaaaaaggta
    35701 aataatcgta gtcttcccaa cttccatctc ttgttaagcc acccatagtg acaaccatat
    35761 gaacatgcgg attaaattct agttttgatc caaaggtgtg gattgtagct actacacctg
    35821 ccttcacctt tcttttctca aaataggcaa gaataatttt tgcggcttca tccattagtc
    35881 ctttcagtaa ggaatctcga tagttttcca tcataaagat ttcccgtaac ccctcatcga
    35941 tcgtaaagat tacgtgccga tgtgtcactt taaacatatc attcgccaca accgctgacc
    36001 acctttggct ttcacctgtt gcacatgttg gacagaattt tccacgacat ttcaagggaa
    36061 caaactttgt ttgatgacat ccttcgcaga caaacagtcg gtatcctttt cgaatatctc
    36121 cacaatatct aaacttgttt acttcccgtt tgacgactag ccgaatcttt cgcccgtgtt
    36181 tctcaacaaa attatcccaa ttatggtgtt cgtcaaaaaa gattgcttcg agaatattcg
    36241 ctttcatagt aatattttac ttgttcaaaa acaaaatgaa aagggctaaa aagactggta
    36301 gtgcagcctt tttagtcctt aactttttat actttcttta ctgttaaaaa aatggagcaa
    36361 aggctagtca agcccttgct ccattttcca ttcttcaaga ggtgtagcta tttcaacacc
    36421 aaagtttaaa tactgtggat gctgtagata catgatatcc attctatttt cgataaactc
    36481 ttttaacgtt gagtagatgt atttttctaa tgctatatct gcccaactac cataatcaag
    36541 tttattcgtg atcttgacgt ttatttcaat ttgagaaaca tcaatatttt gaacatcagg
    36601 aaacttattc agtcttagct cttctctaac cgcttctact agcggttcat attgtccgcc
    36661 tagttcgcta attgttgaaa ctatttcatc tgaattccaa cgatcttcca atacctttgc
    36721 tacattttct ttaggcggtt gtctttctat aaattcttca ggtgtttcat caaactctac
    36781 tctaaagttc aatttatctt gatggttagc atacatataa tcatctctgt ttgattcaaa
    36841 aaagttacga attcctgtgt ctgatttatc acttaactcc ttatttgcta aagtagccca
    36901 aaaatcccaa gttcctttat tttcagtata caaagtaaaa ttaatgttta tatagtttgc
    36961 agtttcagga tacccttgct ctctaagagc atctttaaca atcactgcta agtcagtttc
    37021 aaaattctcc ataaaaaatt cactaaattc ttttggattc cacgtttctt ctaataactt
    37081 ttctaattta cgatctgcca ttattattct cccccacttt actttcactc ttatatctaa
    37141 aaactgctta aaattaagag ctatacctta tcataaaagg tattttatgc tttatttaag
    37201 cctacaattc tatattacaa ttatcatcta gaccattttc ttatgtcaaa taaaccatat
    37261 atattgtctt taatagtttt atttgacttt ttaagaaagt atttactttt gacttttttt
    37321 acgttttaca acatatacgt attgtaatgt tcagctcaat ttattataat ctaaatgaat
    37381 tgattaataa aaattctgag gttcgggttt tttatcaatt cttttctgtt tgtgtttgtg
    37441 atgaaacaat cctttttcgg taggttttgt tatcatcgtc agcacaaaga gctaacgttg
    37501 gtaccgttag ctcttttttt attttactcc gctcttacat agctatctaa attctccaag
    37561 taaaacaatt gattttctcc tatgcttgtt actccacgcc aaattgttgt tgttgctgtt
    37621 gttggagtat ttcttgtctg tgtaatcaat tcaaccattt tacctttttg atttgttgta
    37681 tagtaatcag cagtatagct agatattgga ctattaccag tgcctaccat cgtgccagaa
    37741 atatcaacag gactagactt tactatctga ggaaattctt tttgtatttc cttcatattc
    37801 ttcgtatatt tttcccatga attccagttg taaaataaat taaagaattt cctactttgt
    37861 tccttgattt cagcattccc caattctttg tattgggctt cctgcatagc tttcactttc
    37921 tggttattct tgactacttc gatttgttta cttttaaggt cttccaattc tttgacatta
    37981 ttatcataag catttttctt ttgaaatagt accacacaac aaaggatcac aattatggaa
    38041 agtattccaa tcgccttttt agcagtagtg atttcatgat tttgcataaa aagcaccccc
    38101 agtcactttc ttatcattat ttagtgtgat ggttaatgtg gtatcataca ctttttttcc
    38161 attgtattga acttcaaaat cggtcaatgc ttcatacaac ccactactag atgtcttaat
    38221 tccaaagttt gttagcttaa aagtaaaagg cttatagtac tcgatttttt ctttatcact
    38281 actcttatca gtaattggtg gtttacctgt gacaataaat agttttctca aaaattcttc
    38341 acctgattga tctgcaaact tattttgaac tgatccattc aacatttctt gaatatcatt
    38401 ttctaaatct ttccgtaatc catccacctc atttggttta acctctttaa agaatgtcag
    38461 cttatcttca atatgcacac tgtgtttttc agcttctatg tcctgattct gcttattgaa
    38521 gaataggatt ccaacaagca gtgctaataa cataccagaa agcaaagaaa tgataattgt
    38581 atctttcact ttactattca tctatatcgt ccttcattcc aatttatttt tcgatttcaa
    38641 atttagcttt tcctacaccg ctaaagaaat gcacattatc tgatccgtcc actccatcaa
    38701 tcaaagttac cgaaactccc cttgttggag cttgggttgg tggaacatta aagttagcac
    38761 atagaaatga cccatcttca aacaccgcta taactacacc agtatgccct gcatcgccaa
    38821 cagcccataa ccatccatct gaagcactaa acccataacc tacgattggt ttgttcgtta
    38881 ttttcgctcc tgccgatttg tagctttccc atacgtagcc accatttcca gtagtcggtt
    38941 gattcccatc gtataattgg ctcatataag cccacgtcaa ctctgtacac tgaccttgat
    39001 atattccgtt aaaaggtgaa gttgaccaat ctggttcttt gaattttggt agcgtgatcg
    39061 ctttcccata ttttttcaaa gcttcttcat aagtcatatt cgctattact tgaccttttt
    39121 taccgttaat ttttccttct ttacccattg atccagaacc agaattagca tcatctgtag
    39181 ttgcacaggc atcttctact gttcctgatg ctgagcttga tgaattattt gatccaccac
    39241 cggtacttgt tcctccggca attttattga ttttgcttac atctttagct ccgtccatgc
    39301 ctttgctttt catgtattcc caaatttctt ttgcatttcc accacgtaca gccactacag
    39361 ctgattcgga atctgctgaa atttcccaat tcttatgaaa cgctacggca tttgccacaa
    39421 catcatcaga agcgtttaaa gcataatctt ttaatatagc aacaaatcca ccatcacctt
    39481 tgaacataaa atccaattgc gcttctgtcg tccaccaagc gccaccaaag tttttcttcg
    39541 cccagtttac taatgcagta tggcgacctg ctgtccattg accatagcca atacccatca
    39601 gaccatcagt gaattgtttg ataaattcaa cttctctctg tccatcaccg taataacctt
    39661 ctaccgttcg aggatcatta cctgattctt gtttccagtt acctagaata cctgcgatag
    39721 tagcacctga tagcccatat tccccattca taaatttgta aatatcatca atattttttg
    39781 ctacatcacc tgatacagcg ccacttccag tatcgtttcc atcgctatct gttcctgacc
    39841 cactaccttc agtagtacag ttaaattgtg catcataagt agctatccca tcagcatgta
    39901 tcacttgcgg atttattgtg attacactca ttgcaatccc tgtaaattgc accattaaca
    39961 taagcaacgt ggcaatcttt ctcttagatt ttttcaataa ctacgccccc aaaaagtgta
    40021 cttttttatg ttattatgat aatataataa cataaattaa tagaaaggaa aagctaataa
    40081 atgactgata aaacaagtga tttacctaaa ctagctccaa aaacatctcg agtaaagaga
    40141 aaaaaagatg gaaaaacaaa aaatgctgta aagaaaaagt cagtaaaaga aacatcctcg
    40201 ttactacttg atattccaat gagttctttt gatgacaata cggacgaaac ttctgttaaa
    40261 attgcaactc acgttggaat gaacaatcaa aatgattctt tttacaactt gttaaacagc
    40321 ctaagagagt tggaagataa aaaaatcagg taatcgcatc aaaagctcct gatctcacaa
    40381 ccgatttgga tgctgaaatt atccaaatca aacaagatga gcgatcagtt aaatcgctac
    40441 tgaaaaccta ctttgatggt tttgataaag aactagctcc ttatagccaa gcaatcctaa
    40501 ctaaaccaat acaagctcca catatttcaa tttccctaca aaaaaagagt gatgattaaa
    40561 caatcattac tcttttttag atttctggta agcgctgatc gcaaaaacca tcaacaatat
    40621 tgattcaaaa aatatgttca ttcgtgtctc ttttttccat tatagatttc ccactattcc
    40681 attaaatcga aagtcacacc gattactaca aagattaacg tgaccacatt caaaaacatt
    40741 aaaagatatg ctgataatct catcattttt ttagttcact tactggtaat ctaaacattt
    40801 gaacgattgc actggaaata ccataattag caatgacaaa caaaaaatac gcaataattt
    40861 cacttacacc tagatagatc agtaaaataa ataagtcact taacattgtt agtttcctcc
    40921 cagtatatga ttttcatttt tgggaagtct tttataatcc aattcctcaa aaaaaggaac
    40981 catagtgtca ctaatatagg ttttagtttc aggtaccgcc aaaattcccc aatcaagaat
    41041 ttcttcccat gatacatcat caaattctaa aatattatga tcaactgacc tattaccaag
    41101 ttcatatcca ccaaagatca ccatattatc aatcatgtat agaatttcat caggcgaacc
    41161 atgagttaat gtttcgtcct cttcaagcag ttcgtttaat ctttgtttgt attcctctct
    41221 tttcatactt ttatcccttc tgactcattt ttttgaattt taacattttt aacccaagca
    41281 tgactatctt tacatgctat taatttttat ctccattttg atatttctgt ttttttctac
    41341 tcaccaatca accgtaaatc ctcaatattc tcaccttcaa gcgaatatga atatacttcg
    41401 ccgtaaatat tttctataac tacgacttct tcttcaaagt ctatggactg cacatcaaac
    41461 cattctcctc cgccaaattc gtctatgatt agtacctgca atattttatt tactgccatt
    41521 tcaatttccc cttataccat tctatgtctt ccaaactatt tttcttcttt ccataccaag
    41581 gtttcacgta tctcaaaatt ttctttaaat aagtgttccg gtacttttat aattaactct
    41641 tttcctactt ttatcagata gtctttttca cctaatgaga tttgaccagt cggtaactgt
    41701 atagaaactc ttttagtttt attaaatttt ttagttttca atacagtata cggtctacag
    41761 aatttctcta agcgttcaaa tcttttacta tcgtattgga aataagcttt aggaacagat
    41821 aaagtacaaa aactatcggt aacagcactt atgtcttttt tagaaattat cccaacttta
    41881 gaacttctaa ggaaagttgc taatttctta tatccaccat gacttgtttc aatatagatg
    41941 ctattgtatt ggctgtcgtc tatctcattt attgtttcaa cctttttcct gacaggtgtt
    42001 tcaacgagtt ctcgaacctc ttcttcactg tacgctaata caattaactc ttccccattt
    42061 accatcttta gaacatacgc ttgcttcttt tttcttggct tattttgaga ttcaacataa
    42121 ccagacatgg aatctttata cttccaagca tgtacttttt tctctaattt ctgtatctct
    42181 tttttcagct gtagatattc agacattttt tcattgtaac gttcgcaata taaacaatat
    42241 tcatcttttc caaaatcatg atcaagtcct tcttcaatat gtttattcaa caaaccggaa
    42301 aaatactgat catactgctt ctttcgtaac ttcagctctc gtaaatcttc agacatttca
    42361 tttttccttt ccaattattg gtgccatttc acaatttggg attgactaaa caccataatt
    42421 aatttgtaag ctaacacaat tacaactgtt ggtaattgtg ttagtctcca tcaacttgtc
    42481 tggtggcttt ttttattgca caaatttcat agctctcaaa aagcgcttgg cttgaaaagg
    42541 tgttattcta cgaaccttat tcgccaattt ccaatctgat aaagcaattt gccattcgtg
    42601 catttcaaaa tccggcatga tttctttgat atactgtagc tctttctttt ctctttcttt
    42661 taagaaacgg ctcatcgagt ttaacattgg aactaaggat gcgtaggtac ttgaataact
    42721 tccaatgcgt ttcgtagtaa ttacataatc aataaaaaca ctattaagaa aggtcaagtt
    42781 tataaactct gattcataca ctctaaaatt tgcagttaat cgcttcgcct tgtcacccca
    42841 atagtcactt ttgttgtagg ctttttcccc tcgaatatag cactctgttt ctctttcgta
    42901 ataatagtca tacttttttc atcatcaaat ctgagagttt ttgattatct ttttcactgt
    42961 aaaataatct actcgttaaa cttttaggat aatctttgat agaatatgca tcccaaacaa
    43021 ttctttgaac atattcacga tctatatttt ctctgacttc cccagtccaa aaatgttgac
    43081 cataatggca tctttctatt acattgttag cagaaacttc aaaataggat tgttcccttt
    43141 gtatcctcat accaatcatc atagcgcagg aaataactat taataacaat cctgttttta
    43201 atctattatt ccacatgcag tttccacatc cttatcttga taaaaatcct cttgaccctc
    43261 tccaattact gttttaaata taaccaccaa aacaagatca tgctaagaaa tccaagagta
    43321 tataagatga tacattcttt gttaattatc caaaaaactc tgatttcttt gagcttttca
    43381 cgcattagga aacaccttgt tatatctttt ttgtatttct ttcaattgtt ttttaaaact
    43441 cataaacaac tgttcatgat ctggtctaag cgttagaata tctaaattat ttatcttttt
    43501 taattgtgta ataaaatcta ttttggattt tctttcaata tcaaaaccga caataatctt
    43561 tcctgttgga tcaacgcatt tcacttgaat aactttgtca ttttgcgata gctctaatat
    43621 tgatgatttt tcttttgcct cttccaaaag atgttctaac acttcgttag gtgttccatg
    43681 atagtaataa atcatggtct tctcgaaaat ttttatcgga tcaacaccat attcttttcc
    43741 gattcgataa aaaaatttca ttggaatttc ttccggattt ctgttcctgc ttgaccagtt
    43801 agagatggtt tgataatttg caaaatggat tcgttccgct aatctctgaa ctgtggtctc
    43861 taaatcttct tctattaatt gttttacagc actaatgttt tgtgacattt gctttctatc
    43921 ccttcaaatt cgttgcatta tcaattctaa gatttcatgt tttagtgcat ttctatctac
    43981 attttgcttt tttaactctg caccataata tcttcgcaat cccttatcca agcatacaat
    44041 tccttgatct aatagatcat attccgcttt ttcaaacctt cgctttgcct gctcaacaag
    44101 caaaatgata ttgtgatgta tctgattaaa ctgccgatca tattcctcta aagttttagc
    44161 atctaagtta gcaatatgat cctctgctaa tttttgtgtt aaaaataatt cgactttctc
    44221 agatttcaac atctgtattt tttcatactc ttgttttgct tggatatagt catctttcaa
    44281 gctagacatc taactcatct ccttgcctgt ataaactgat acggactgtc caaaattgaa
    44341 taggttggtg atgacttcaa gaagacttca cctttttcac atgaaaataa accaattaat
    44401 tcttcaattt catttacgat cagatattta ttagttaaaa ttttcccatt ttctttttct
    44461 agctcgacaa tcgcttgatt ccatgtattt tgcactaaat cttgaatcaa tttcaatcta
    44521 tccacttttt tcatctcata cagggcaatt tcagcttgtt taatgccttt taatttgcga
    44581 aaggcatatt tgtattgtgt gtaggttaaa aagcctgtgt agttatacat gggctttcct
    44641 gatgtcttgt agtcatttaa gcttggatat atttcagttt tccatttttc ttctgaacgt
    44701 tgatcaataa ttcttaattt ttcaggtaaa tcaatttcat agtattcttc aattttcagc
    44761 tcacgataaa gtagatgttt ttccttttct ttttcaatta caaaagaatt atttcccttc
    44821 agtttagcta tttcttcact tgtgagacca agcctaattt tttctacttc acttctaagt
    44881 tcacgaatac ttgttgcctt taaccacttc ccatttgcac cattattgta accggtaagt
    44941 aactgtattt tataaattcc ttcaccatga agcaccttat atataccaac ctgattcttt
    45001 tgcggaatat gagcttcatt tgcactgatt tctttcatta cgcattctcc tttataatct
    45061 agttaattag cttgtgtgtt tcgagtagtt gagtaagaac gtttgtttca gaaatcattt
    45121 atttgttatc acttaatttt aaaaaaatag ggcttacgcc ctaaagatct atttaacttt
    45181 ggattgatcg tccataacag gctctgattg ttgatataat ttatatgctc ccaaatccat
    45241 ataatattta gttgtacttt caatcatttc atcagttgta tttgttgtca ttcccattac
    45301 atcccagtat agtgtgccgt taactttctt tggtgttact actgcaactg ttggcgtatg
    45361 atattgattg ttctcatcag ccagaccagg aatgttttgt acccactcag gtacaccatc
    45421 agtaatatct acagcaactg cgtaatactc gtaagctggt ttatttatgg taatatcatg
    45481 cattaatgtt ggagcataac taaatccttc ttttatttct tgcatgattt ttgattctgc
    45541 tttttgacaa tctggacaat caggtttgta aagaacgata gtcagatttt tattttgcaa
    45601 tggatcattc ccataatttt catcattttt tactgtatta ataaagttgt tataaacttc
    45661 atccggcttt tgacctttat taatgtcttc gtatttttga tacttttcag cattattttc
    45721 agtcattgaa gacattgttg ttgatgccga tgtagtgctg tttttagtaa ccatcgtact
    45781 actagacttt gtgtctttgt tattattagc actattagtt gtaccacatg ctgtaagggt
    45841 tattaatgct gctgtcgata acaatacaac cttcaattta gttgatttca ttttattcac
    45901 ctatcctttt ttcttttgtt taacaataaa agaataaccc gtactatcca ataaaacaac
    45961 agcatcaata tggaaaccca aaccatttgt acaatccaag cataaagact aaataatagg
    46021 tattgtggat ttttttgaat gattgtattt gagatgccat ttcctacagt aaaatacatt
    46081 gttacgaaaa taacaccttc aattatcaag tgatttgttg gttgatttat aatttttttc
    46141 atatttttac tcctaaacta aatttattct tcctgctaaa tattgaaaat tatatgggtt
    46201 ctgcacatat tccctaagtt ccttaatact tgtttcaata tcaccaaagg ctgttttaat
    46261 gtttgctgac ccatctttat atacaatcat ttccccttca cccatacaaa aagaaatttc
    46321 agtattagaa ttgattgttt tttcagcacg accattgata atttcttgac catcacgcca
    46381 tataaaatac ataagataaa atacctcata agcgttgtat ccagtatccg ttgtcattga
    46441 taccaaaaca tcagcatctt gtattcctga taaagctaat ccaatttcat ggatcacatc
    46501 aacttcattt tcttcccaat ctccactttc gaagacggta taggtttgat tgttagcaaa
    46561 tggttttctt tctatatcga acattccttt ccaatcaaga atcatgtacc cgattaaatt
    46621 gtgaaagaaa attagataaa ataaatacaa taagatgcta actacaaaaa tatcagccat
    46681 tattgacata ggattatcag gatataacca gatgtaaaac gattgtttca aatccatttt
    46741 ttcatcatct cactctacat atttatgtta ttatgataac acaacaacat aaatatgtct
    46801 cgctttttaa ttttttttta tggtaaactt gtcatacaaa taaaaaaagg agatttatat
    46861 gtttatatta gatgatgaaa taaaaaaagt taaaaatcct agaattattc cattattaga
    46921 agaagttaga agtagttttt atcagggaaa ttatcgttct gcaatagctg tcaattacag
    46981 tgcgcttatt ttagatttaa ttgataaatt atctgattta gcaaatattt acgaggataa
    47041 tacttctaag aaaattttag aagatatagc tagactaaga aaaagtgatc caaactctcc
    47101 aaaatgggaa atggaactac tagaaaaagc ttatagttca actgagctaa ttgatagcta
    47161 tgaatatgag gatttaaaat atattaagga tcaaagaaat tattcagctc atcctgtagt
    47221 cacttacaac ggtaatactt gggaattaag agatataaca aaagaaactt gtcaggatgt
    47281 tatacggaag tcctatgaaa ttatattcct aaaaaatcca atattaggaa aaaaagtaac
    47341 gatcgaaatt atacaatatg caagtcgcat acatgctatg tctgttacac ctgaagaatt
    47401 tcactctgca ctaaaaaata gctatctaaa taaactaagc gaaaaagcca aagaaaacct
    47461 atgtaagaca gcctttaagt ttgtttttca attatcttat ggaaatgagg aagcagatag
    47521 agatagggaa agtactttca gactacttaa tgccctaatt tttgataata aagaattcta
    47581 tttaaatatt ctaaaaaaag aaattgcaaa gtataggttc acagctgaat caagagagga
    47641 aattaataaa tcacttggtg aaaatcaaca gatcacgtat acaaaagggt tctttttact
    47701 tacttttata gctacccatc cagaattaca acatgatttt tcagacgaga caattcaaaa
    47761 tttacaaata tcaataaatg attttaaacc gaaacaacaa gtactaacag aaatagaata
    47821 ttactaccgt ttacgttccc ttgcagttct aggaaacaac aatgaagaat tacaaaatca
    47881 cttaaatagt ctagttgatc ctatactcca gcaaaaaatg agagtttctt cgctaccatc
    47941 ttcaacatta gaaacaatat ataatcaata tttatatttt ggtgaaaaag agatgttcat
    48001 agattttatg atcgaacatc ttaccgatgc tagttcattc aggttagcag ataaggatat
    48061 ggaagtatta ccatggattt acaataaatt aaatcaggag caatttaaca aattactata
    48121 caacctaaat ggaaataatc aattttacaa aaacagtaat tttccgcctt ttatttctaa
    48181 tctgttagac ttttataatc agaaattcca agtgaattta cgtaaacatt atagtgggct
    48241 tctatatcca aatgcagtga ctatggatca gggttttcaa ttaaaggata aagaattaaa
    48301 aaaactgtat gaattagctg aatcgaaaag tgatatgtat ctagacataa tagataatat
    48361 tattaataag tctgaagact atttaagaaa agaaatcaat tccgagaaag aattgttaaa
    48421 ttatgttcac aaaataaaat aattttttat aacacaagat gcacttttat agagagtgta
    48481 aaatattttg tgtaaatgaa aaaatccata caaaaaagga agtc
//
LOCUS       DAIGUC010000019        43468 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.019, whole genome shotgun sequence.
ACCESSION   DAIGUC010000019 DAIGUC010000000
VERSION     DAIGUC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.019"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..186)
                     /locus_tag="NOB46_001102"
     CDS             complement(<1..186)
                     /locus_tag="NOB46_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058054.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKN"
     gene            complement(201..2885)
                     /locus_tag="NOB46_001103"
     CDS             complement(201..2885)
                     /locus_tag="NOB46_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058055.1"
                     /translation="MKIIGKKIANRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TKSQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLSTIVVGLMILSLVIVGYKMIIGKGTVDLKSVGMNVVMSISLI
                     LLMPTLIHSGIEFSKTFYNDSTTITDSDEGVAWSLIEQGVTDLAYINKTDQYSMIDKT
                     NDRNNLTKENFWKTDLTQVLTDNVLDKMEKENPIADNLRYELVENSDNEFVATKFSDN
                     FLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRVLGVLV
                     FATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFVNYLNAGEGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKN
                     SGGNDQAEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMASERATK
                     PFKSMRDIANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNTNHASAIQQKVKQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEIMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQDRRSVDVRENLQNTTSSQSGNRIVDVRENVQSSASNQSRTVDV
                     RENLQNTTSSQSGNRTVNVRENVLSSGTSQPRTVDVRENLQNTTSSQSGNRTVDVREN
                     VQSSTSSQGFKTVDVRENVQKDSGEMKEKAQKINIVEDRKSAKKFDSNHETVIIDSEI
                     RENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLKK"
     gene            complement(3110..3979)
                     /locus_tag="NOB46_001104"
     CDS             complement(3110..3979)
                     /locus_tag="NOB46_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HCI1058056.1"
                     /translation="MAEKRMLSKTFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYVKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKLDVILKSGQVEPLRVDLMEKWYPVGIPSINHLEVQSSQDQISSDK
                     SSLVKNSIDKINQVDTIINEEIINEKGIQLIHKLGDRFTKSQREKFVQLIVDMKNSTE
                     REFKIRIDGPHYYEQTNKMIIRLFNTINEKLNLGKELNEMKYVNTVSRNHWKEIALEE
                     QDNRMYIIDALSK"
     gene            complement(4133..4435)
                     /locus_tag="NOB46_001105"
     CDS             complement(4133..4435)
                     /locus_tag="NOB46_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058057.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGESFERK"
     gene            4637..5434
                     /locus_tag="NOB46_001106"
     CDS             4637..5434
                     /locus_tag="NOB46_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1058058.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            5485..6627
                     /locus_tag="NOB46_001107"
     CDS             5485..6627
                     /locus_tag="NOB46_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1058059.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENYSVKMYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(6725..8116)
                     /gene="sufB"
                     /locus_tag="NOB46_001108"
     CDS             complement(6725..8116)
                     /gene="sufB"
                     /locus_tag="NOB46_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCI1058060.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(8121..8591)
                     /locus_tag="NOB46_001109"
     CDS             complement(8121..8591)
                     /locus_tag="NOB46_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HCI1058061.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(8578..9813)
                     /locus_tag="NOB46_001110"
     CDS             complement(8578..9813)
                     /locus_tag="NOB46_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI1058062.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(9810..11096)
                     /gene="sufD"
                     /locus_tag="NOB46_001111"
     CDS             complement(9810..11096)
                     /gene="sufD"
                     /locus_tag="NOB46_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCI1058063.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(11109..11882)
                     /gene="sufC"
                     /locus_tag="NOB46_001112"
     CDS             complement(11109..11882)
                     /gene="sufC"
                     /locus_tag="NOB46_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCI1058064.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(12079..12927)
                     /locus_tag="NOB46_001113"
     CDS             complement(12079..12927)
                     /locus_tag="NOB46_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI1058065.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(12951..13637)
                     /locus_tag="NOB46_001114"
     CDS             complement(12951..13637)
                     /locus_tag="NOB46_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058066.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(13630..14664)
                     /locus_tag="NOB46_001115"
     CDS             complement(13630..14664)
                     /locus_tag="NOB46_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1058067.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(14727..14983)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15059..15397)
                     /locus_tag="NOB46_001116"
     CDS             complement(15059..15397)
                     /locus_tag="NOB46_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HCI1058068.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(15399..15755)
                     /locus_tag="NOB46_001117"
     CDS             complement(15399..15755)
                     /locus_tag="NOB46_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCI1058069.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(15761..16948)
                     /locus_tag="NOB46_001118"
     CDS             complement(15761..16948)
                     /locus_tag="NOB46_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI1058070.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(17139..17984)
                     /locus_tag="NOB46_001119"
     CDS             complement(17139..17984)
                     /locus_tag="NOB46_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1058071.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            18218..19183
                     /locus_tag="NOB46_001120"
     CDS             18218..19183
                     /locus_tag="NOB46_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCI1058072.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            19560..20603
                     /locus_tag="NOB46_001121"
     CDS             19560..20603
                     /locus_tag="NOB46_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCI1058073.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(20665..21129)
                     /locus_tag="NOB46_001122"
     CDS             complement(20665..21129)
                     /locus_tag="NOB46_001122"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCI1058074.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            21375..22322
                     /locus_tag="NOB46_001123"
     CDS             21375..22322
                     /locus_tag="NOB46_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1058075.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(22533..24605)
                     /locus_tag="NOB46_001124"
     CDS             complement(22533..24605)
                     /locus_tag="NOB46_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI1058076.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(24538..24915)
                     /locus_tag="NOB46_001125"
     CDS             complement(24538..24915)
                     /locus_tag="NOB46_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HCI1058077.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(25044..25622)
                     /locus_tag="NOB46_001126"
     CDS             complement(25044..25622)
                     /locus_tag="NOB46_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1058078.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            25754..27046
                     /locus_tag="NOB46_001127"
     CDS             25754..27046
                     /locus_tag="NOB46_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI1058079.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(27106..28224)
                     /locus_tag="NOB46_001128"
     CDS             complement(27106..28224)
                     /locus_tag="NOB46_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HCI1058080.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(28238..29659)
                     /gene="arcD"
                     /locus_tag="NOB46_001129"
     CDS             complement(28238..29659)
                     /gene="arcD"
                     /locus_tag="NOB46_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HCI1058081.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(29905..31026)
                     /gene="mnmA"
                     /locus_tag="NOB46_001130"
     CDS             complement(29905..31026)
                     /gene="mnmA"
                     /locus_tag="NOB46_001130"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCI1058082.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            31430..32029
                     /locus_tag="NOB46_001131"
     CDS             31430..32029
                     /locus_tag="NOB46_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HCI1058083.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(32167..33453)
                     /gene="efmA"
                     /locus_tag="NOB46_001132"
     CDS             complement(32167..33453)
                     /gene="efmA"
                     /locus_tag="NOB46_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HCI1058084.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(33724..34068)
                     /locus_tag="NOB46_001133"
     CDS             complement(33724..34068)
                     /locus_tag="NOB46_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HCI1058085.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(34205..35350)
                     /locus_tag="NOB46_001134"
     CDS             complement(34205..35350)
                     /locus_tag="NOB46_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI1058086.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(35530..36504)
                     /locus_tag="NOB46_001135"
     CDS             complement(35530..36504)
                     /locus_tag="NOB46_001135"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI1058087.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(36584..37459)
                     /locus_tag="NOB46_001136"
     CDS             complement(36584..37459)
                     /locus_tag="NOB46_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HCI1058088.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            37589..39496
                     /locus_tag="NOB46_001137"
     CDS             37589..39496
                     /locus_tag="NOB46_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HCI1058089.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(40037..43315)
                     /locus_tag="NOB46_001138"
     CDS             complement(40037..43315)
                     /locus_tag="NOB46_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HCI1058090.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        12263 a         9119 c         7721 g        14365 t
ORIGIN      
        1 atttttttcc agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc
       61 ttcttgaatc atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt
      121 tactgattca cataattcgt caagttctaa gaaatcatgc gtactaatct ttagaattaa
      181 ttgcatgaca atcccccctt ttattttttt aatagattat cgaaaagtgg attaggatca
      241 ttaagtgtat ctctgaataa ctcattgtct tcataagtga atcttcgtct tgattttgat
      301 cccttatcat tttcacggat ttcactatca ataatcactg tttcatgatt tgaatcaaat
      361 tttttcgctg actttctgtc ttcaacaata ttgatttttt gtgctttttc tttcatttct
      421 ccactatctt tttgaacgtt ctcccgaaca tctactgttt tgaatccttg actacttgta
      481 gaactttgta cattttctcg tacgtctact gttcgatttc cactttgact acttgtagta
      541 ttttgcaagt tttctcgaac atctactgtt ctcggttgac ttgtcccact acttagtaca
      601 ttttctcgta catttactgt tcggtttcca ctttgactac ttgtagtatt ctgcaagttt
      661 tctcgaacat ctaccgttct cgattgattt gacgcactac tttgtacatt ttctcgtaca
      721 tctactattc gatttccact ttgactactt gtagtattct gtaagttttc tcgaacatct
      781 actgagcgtc tatcttgact acttgtagaa ttttgtagat tttctttgac caatttttct
      841 aatccggtat ttgaattttt agcttcttga attctttctt tggtcaacgc ttctttttcg
      901 tccatattag cccctgtacg cccttctaca cgtttcctca acatttcctc acgattcatt
      961 atttcaggcg tgtattttgc ttcctgtcgc ttctgattaa ttaattcttc agcagactta
     1021 gcttgaccgt gcatagcatt tttacgttct tcaatatctt gtttaacttt ttgctgaatt
     1081 gcacttgcat gattagtatt tgattcagca ttatttttca ttgcttcacg catacgttca
     1141 gaactagaca taattctatc agcgttttca actttagcgc catcttttct atccgaaaga
     1201 cgcgttggca tagaatcagc atattttcca gtttcatctt ctttattttt agctactata
     1261 ggtttgctat ttttattaat agcggacacg gtaccatcat ctaaaccttc tttaaattta
     1321 ttcttggtat cattagctat atcacgcata ctcttaaatg gttttgttgc tctttcacta
     1381 gccattgtag ctccatccga agctaagcct gataatccac gttcacgagc atacccaagc
     1441 gttttccccg ttttattagc tttttgagaa agtgattgac caaagttgcg ttcaggtttt
     1501 cgttcttccc cttccgcttg atcgtttcca ccactatttt tcccaccttt agatcggttc
     1561 ataccacctg ttcctttacg aaacagcata gctcccatac caaatgctga agcaagctgg
     1621 ccatagcctt cttttaaacc aatatccacg ccaaagtaac gcatgactgt tccactaccc
     1681 tttattagaa cgaacacggc acagatataa gcaattgttt ttataaaaat attcgttgag
     1741 ataccttcac cagcgtttag ataattaaca aacattgcaa acatagacaa tccgaatccc
     1801 tgaaaaccga cagtcaaata acactgtaga atatctgaca aaacttgttt tgatcgttgt
     1861 cctgtttcta agtcagtagc aaataccaaa actccaagta cgcgtttaaa tgctaactcg
     1921 agtattgctg taattataat gaaagcacta aaaacatacg ctactgctaa agcaatcaat
     1981 ccaaatgaaa ttccccacaa gttcgcttga tagcgataat atcctgattt gataccatca
     2041 acaaaggttg acaaaaaatt atctgaaaat ttagtagcaa caaattcatt atcagaattt
     2101 tcaactaatt cataacgcag attatcagct attgggttct ctttttccat tttgtcgagt
     2161 acattatctg tcaatacttg cgtaagatcc gttttccaaa aattttcttt tgttagattg
     2221 ttccggtcat tcgttttatc gatcatggaa tattgatccg ttttattgat ataagctaaa
     2281 tcagtaaccc cttgttcaat cagcgaccac gccacgcctt cgtctgaatc tgtaatcgta
     2341 gttgaatcat tataaaaggt tttagaaaac tctattccgc tgtgaatcaa agttggcatt
     2401 aaaagaatca atgaaattga cattacaaca ttcattccaa cagattttag atcaaccgtt
     2461 cctttaccta taatcatttt ataaccaaca atcactagtg aaagtatcat taagccaaca
     2521 acaatggtac ttaaaactga ttgatagact ttgttcaatc cagcactttc cacaaagcta
     2581 aacaaatcta aaacctcggg aatcatattt tgaatgccat cgacaacagc gaacattgat
     2641 tttataacag accagcctat ccacataccg aactgactgt aaaaatttcc gttatatttt
     2701 ttaagataat tctgataaag tggattagtt aaaaactcag tttggctttt tgtatcatca
     2761 aaccagttga aaatactgcc ttctgcaacg ttactcgtaa aaataatcat agctatgaga
     2821 ataagaaaac taatcaacaa ccaatttatt tttctattgg caatcttttt tccaataatt
     2881 ttcattgtta cctccctcag cccagtttct gaggctctca gagagctttt gagcaatttt
     2941 ttggtcaatg atgatatgag ttacataact atcattcact gctcttaaat cgagaacaat
     3001 agtgttgaag cagatacact cgattaattc aagtgtatct gcgttttggt caagacagca
     3061 gatttgatct attagacgat ttccaatcat attaagagtc ctttcttgtt tatttactta
     3121 gagcatctat gatatacatt ctgttatctt gttcttctaa agcaatttct ttccagtgat
     3181 ttcgagatac cgtgtttaca tacttcattt cattcaattc tttacccaag tttaatttct
     3241 cgttaatcgt attaaataat ctgattatca tcttatttgt ttgttcatag taatgtggcc
     3301 catcgattcg aattttgaac tctctttctg ttgaattttt catatctact attaattgaa
     3361 cgaatttttc tctttgactt ttagtaaatc tgtcacctag tttatgaatc agctgtattc
     3421 ctttctcgtt aattatctct tcattgataa tagtatcaac ttgattaatc ttatctatac
     3481 tattcttaac taaactagat ttatctgaac taatctgatc ttgacttgac tgaacctcca
     3541 aatggttgat gctaggtata ccaactggat accatttttc cattaaatcg actcttagcg
     3601 gttctacttg gccagatttc aaaatcacat caagttttat tggctttaat tttgagaaaa
     3661 attctggttt taagttcaat aacttgaagc gataaataga tggtttatac ctatctattc
     3721 gtatattttg gttttgtaac caatgcggta ggaatgctaa caaatcttca tttaaaaaaa
     3781 atacaaaacc ttttgtaaaa agtatcttta catcatcgtc aggagtcccg agcattttca
     3841 cgtatggata tgcttcaaca attccgtcat cgtctgcatt tgtgttcaga tatacatata
     3901 ataattttgc tgaatctgac atcttcataa aacttgcatt atttaaaaat gttttggaca
     3961 gcattcgttt ttctgccatg gatttcacac ttctttctat ttgaatggta aaataaattc
     4021 aaataaagtt ttatcagaac tttattgttg ggtgtttccc ttcgtctaca aactatcggg
     4081 agcactcttt tatatatttt tttcaattct tttcaagtct aaatttgtta tttcattttc
     4141 tctcaaaact ttcacctctt ttcattcgag caaacataaa ctcattaact gcctttttcg
     4201 aataaaattt tcttgcccct aattcaacaa cgggcaatcc ctcatttctc accgcatttt
     4261 ttaaaaagtt ttcgctcaca tttaagtatt ctgccatttc tttttgattt agatattctc
     4321 tagtcatacc cgcattttct tgagccttct caatcgcttt tgtagcaatt tgataaaact
     4381 gctttagaaa catttcctcc tgttcttctg aaatcattaa ttttattgct tccacaaaaa
     4441 cctctccttt ttaattaatt attctataac tcctctacct ttataagtac aaataaatac
     4501 aaattgcgta aaaaaatgta tttatttgta tttataagaa taaagtatca tactccagat
     4561 aaaaagtaaa tacttttaaa tacttttgtt ttataaatat gatatactat ctttaaaaat
     4621 aaaaaggaga aaaaagatga agccaaatcc ttcagaagca ggaaaacgaa tcaaacaatt
     4681 acgcctttca tgtggtttta ctatggaaga acttggaagg aaaatagata attcaccacg
     4741 tgcgaccata tccaactggg aacgtgggac caatttacca aatccacaaa agctgaaatt
     4801 attatcaact atcactaatt caacaattga ctggattaaa tggggaactt tagaagaata
     4861 tataacttca taccttatcg atatagggta tgagctatat attaaggact ttccagaaat
     4921 acctcacaaa gtctttaaag acattcaaga aagatatagt gatacgtttt cgctagataa
     4981 agactatgag ttattgaatc ctataataaa aaatatattt acaaaatatt actcaaaaga
     5041 ttttgaaatt tatctaaatg agatacttgc taataatatc aatcctctga ttgaagagta
     5101 cgctaaccaa agacactcta tctctaaaga gctatttttc aaaagagcca acagtaaact
     5161 tcaagacaag ataagaaatg gtgatttcaa atacggtgaa aaagaaagaa tgattgattc
     5221 tttaaaacag ctattagacg aaatggactt agcctataaa gatatttcaa agtattcatc
     5281 tgtcgaggat ttcttttata aaattactaa aaaccaattt gaaacagaaa aatttatttc
     5341 agatcttagt aaaaaataca atttcccata tgagaaaaat agtataatcg caaaattttt
     5401 aactgataat cacgataaat ttaaaaataa ttgattcttc aaataacttc tctacctgca
     5461 ataatgaagt aaggagagaa tcaaatggca acatttttta gttataaatt acaaaatggc
     5521 gaaaaatatt ggggatttga aacttattta gggaaagatc ccaagactgg aaaagatata
     5581 cgtacaaagc gtagaagatt caaatcaaaa gctgaggcgc aaacagcact taatagacta
     5641 cttgtagact ttaaagaaaa acaagagttt aaaatcaatg ttacaacttt tcaagagttg
     5701 tatgaattat ggattgataa ctacagaaca agagtaaaac cgtcttctgt tgccgttgct
     5761 caacgttttt gcaaaaacca tatattacct gcttttgggg aattacgatt ggataaaata
     5821 agtgttagct attgccaaaa acaggtgaat gaatggcaca aaacattaaa acaatatggt
     5881 ttcttgagaa aaacaactgc tcaaattttt aaatttggag tagcaatgga agtctgtaag
     5941 gataatccta tgtctaaaac attgcttcca agaaaaattg aagaagaaca acccttgaag
     6001 ttttacacga aagatcaatt acaactgttt ttacagaata ctaaagaaaa ttattcagtt
     6061 aaaatgtaca cttttttccg tttattagct tatacaggaa tgcgtaaaag cgaggcattg
     6121 gcgcttcaat gggaagatat agactatttc aacaaaacaa taacaattgg taaaactatc
     6181 gctcaagacg agtttaatca agtagtttta caagtaccta aaactaaaaa ttcatcaaga
     6241 acgattcagc ttgatgattt tacacttaaa caactgcgta tttggcaaca agaacaaatg
     6301 aaaataatga tcttatatgg ctataacacg aattcaccaa aacagtttct tttcactaca
     6361 aacacaaaca agttgtacta cccccaagta gtaaacgatt ggttagactg gatttacaaa
     6421 aagacaccga tggagcctca aattactcca catggattta ggcataccca ctgtagctta
     6481 ttgtttgaaa gtggtgcgtc gataaaagaa gtacaggaac gattaggtca taaagatatt
     6541 aaaactacca tgaatatcta tgctcatgtc acaccacaat ctgttaagaa aactggtgac
     6601 cgatttgcaa aatttatggg cgaataattc caaacgtagc caaaaacgta gccaaccatt
     6661 aaaatacaaa taaaaaaacg ctcgaaacgc tttaatatca acgtttcgag caatgaaata
     6721 gttgttaacc cacagaccct tccatctcat aactgatcaa tcgattgagt tcgactgcat
     6781 attccattgg aagttctttg gtgaatggtt caacaaagcc catgacgatc atttcagttg
     6841 cttcagattc ggtcaggcct cggctcatca gatagtagag ttgttcttct gagatttttg
     6901 agactttggc ttcgtgttct aaagagactt ggctgttgtg gatctcattg aatgggatcg
     6961 tatcggattt cgaccattcg tccatgatga tcgtgtcaca ttcgatatga gagatcgaac
     7021 ccgcactgtt tttggcaaag gttacttgtc ctcgatagtt tacttctccg ccgtcttttg
     7081 aaattgattt agagacgata gagctagatg tatttggtgc attgtggatc atttttgcac
     7141 ccgtatcttg gatttggttt gctcctgcaa aggcgatgga gagcatggtg cctcgtgcac
     7201 cttttccatc taagtaaaca cttgggtatt tcatcgttgt ttttgcacct aggtttccgt
     7261 cgatccattc aacggttgcg ccttcgtatg cttttgctcg tttggttact aagttgtaca
     7321 cattgtctga ccagttttgg atcgttgtgt aacggcaata cgcatctttt cttgtaaaga
     7381 tttctacgat ggcggcatgc aggctgttac ttgaataagt aggtgccgta caaccttcga
     7441 catagtggat gcttgctcct tcgtcaacaa tgatcagcgt acgttcgaat tgccccgtgt
     7501 tttccgcatt gatccggaag tacgtttgta atggaacatc gactttgacg ccttttggca
     7561 cgtaaataaa ggtcccacct gaccatacgg ctgaattcag cgctgctaat ttgttgtcgg
     7621 ttggcggtac aagttttgaa aagtactctt tgaataattc agggtattct ttcaaagcag
     7681 agtcagtgtc agtaaagacg attcctaact tttcgaattc atctttcata ttatggtaca
     7741 cgacttctga ttcatattgt gcggaagcac cggctagata agctcgttca gcttctggta
     7801 taccaatctt ttcaaatgta tctttgattt tttctggtac gtcttcccag tcacgagcgg
     7861 gtttgtcact tggtttttgg taatatttga tggcatcgaa atcgatgtct gaaaggtcgg
     7921 ggccccatgt ttgcattggc attttgttaa atgtttctag agatttcaga cggaattcaa
     7981 gcatccattc tggttcgcct ttgattcttg acatctcacg gatcacttct tctgtcaagc
     8041 cttctcctgt actgaaaacc ggttcgacat catcgtgaaa cccgaattta tattcttcta
     8101 attctggtac gcccatgttc tcactcctct tccttgtggt aatgatggaa agctgcggta
     8161 ccatcgtttt ccattgcttt tcctagtgct ttccaggcaa gtgtcgcaca tttgatccga
     8221 gcgggaaatt tagctacacc accaagcata gcagcatcgc ctaattggtc gggatctttg
     8281 acttcttttc cttggacaag ctgtagaaag tctacagtta aatgttctgc ttcttctatt
     8341 gattttccga tgacggcgtc tgtcatcatc gaggcacttg ccgtactgat ggagcagcca
     8401 ctgccgtcaa aggcgatatt tttgatgatt ccgtctttta catcgacttg caattcgatc
     8461 acatctccac atgtggggtt gttcaattcg atcttgcttg tcgagtcagt caagcttcca
     8521 cgatgatgcg gatgggaaga atgatccaag atcacttgac ggtataaatt gtctaattta
     8581 gatagtccca tgttggaaaa actcctttgt tgccatgatt gcttcaacta aacggtcggc
     8641 gtcttgcgtt gtgttgtaga aataaaagct cgcgcgagca gtcgctgata cttcaaggta
     8701 cttcaatagc ggttgcgcac aatgatgacc tgctctgacg gctacccctt ccatgtctaa
     8761 agctgtcgcg acatcatggg gatgtaaccc atccaaattg aatgcaacga ctcctgtccg
     8821 aaaattcggg tcttgtggac cataaacagt caatccatca attgcttgta attttggcaa
     8881 cacataagcg gctagttctt cttcatatcg atggatattg tccataccga gtttttgcaa
     8941 ataatcgatt gcatggccta atgcgatagc gccggcgata tttggtgtcc ctgcttcgaa
     9001 tttccaaggt agttctttcc atgtactgtc gtataattcg acaaaatcga tcatttcgcc
     9061 accaaattca acaggttcca tttcttctaa ccattttcgt ttaccatata aaacaccaat
     9121 acctgttggt ccgcacattt tgtgtccgct gaaagcaaag aaatcacagt ctagtgcttg
     9181 gacatcaatg gccatgtgcg gggcagattg agcaccatct actacgatga ccccgccgtt
     9241 ttcatggaca agttcagcta attcttgaac aggattgaag acacctaaga cattggatac
     9301 atgagcaatg gagacgattt tggttttgtc cgtaatcttt ttcgctgcat cctccatatc
     9361 caggaagcct tcttctgtta gttcgatata tttcaagaca gcacctgttc gttttgccaa
     9421 ctgctgccac gggataacat tagaatgatg ttccatgtaa gagagcacta tctcgtctcc
     9481 tgctttgata tagcggtcgc cgaaggttct ggctacccaa ttcaagcttg tcgtcgtacc
     9541 acgagtaaac agcacttctg ctgtttcttt tgcatggatg aacgcccgta ctttttctct
     9601 tgcttgttca taatcatggg tcgcgcgttc tgctaacgta tggacaccgc gatgaacatt
     9661 ggcgttatcg tgttcgtaat agtacgctaa tgcctggagt acttgttttg gcttttgggt
     9721 cgtcgctgca ttatccagat aaactaaagg ttcatcattg acgtcttgaa ataagatagg
     9781 aaaatcattg cgtagctttt tagcatcgat catccattca acttcccttc gattacttcg
     9841 actaattctt tccgaacttg ttctacaggg attgctgtta agacagaacc gaggaatcct
     9901 cgaatcacta agcgctctgc ttcttcttta tgcaatcctc tactcatcag atagtacatt
     9961 tcttctggat caactcgtcc tacactggca gcatgtccag cagttacttc gttttcatcg
    10021 atcaaaagaa taggattcgc atcaccacgt gctttatcag aaagcatcaa gacacgactt
    10081 tcttgttggg catctgcacc ttttgcccct ttcaagatgt ggccgatacc attaaaggtc
    10141 aatgttcctt tttctcggat cactccgtgt tgcaaaatat gcccgatcgt atgaggggct
    10201 ttattggtta ctcgtgtatc gattccttgg atttgtctgc ccgagctgat tgccacgatt
    10261 ttgacttctg cgtgtgcacc ttctcctgct aaatctgagt caaagtcagc gatcacatga
    10321 ccgtcattca tgacaccaat tgcccagtcg acagaagcat ctcgtaaaat gtgcccacgg
    10381 cgattcatat aagaagtaat attttctcct aattgatcta cggctgaata tttgattttt
    10441 gaaccagctt tagcgatgac ttccacgatg atattacctg atgattttgc tacttgttct
    10501 ttggttgtct ggaaacgttc cagataagaa aattcactat gttcatctgc cacgatcaac
    10561 acatgcttga agaagtgctc atcggatgcg ccatcttgaa tgaataagga ctcgagtggt
    10621 tcatcgatca cgacattttt aggcacatac aggaaaatac cgctgttcat aaaagctaca
    10681 tggagtgcag tcaattggtc ttcgttcatg tttactgctt ttttcatata atattcttgg
    10741 actagttctg gatattcgat cattgcagtg aacaagtcgg taaaaatgac tcctttttct
    10801 gctaattcca caggcagttg ttcaaaaatc gtccatgaac cttgttggac aagcacagga
    10861 ttgtctttca ttgcatcaaa tgccggaatc gtgcctgttt cactgatggt ttgtgtttct
    10921 ttcacatcaa ataacgacca gcgatggaat ttcacccgat cgatatgcgg caatggcagt
    10981 tcatctgctt tcgctagtgc gtcttgacgg aaggttctca tccaatcagg ttcgccttta
    11041 cttaaagaaa aatcatttac cgcgtcaaga taatcgagcc agtttttttc tttcattctt
    11101 gctccccctt acgcttcttc ttctttatag tcgattccta attctttact gataccagcg
    11161 tagccttctg cttccagacg tttagctagg tcagcattcc ctgtcatgac tactcggcct
    11221 tccatcatga tgtgaacgac atcaggtgtg atatagttca ataatcgttg atagtgggtg
    11281 atgatcaatg caccgaaatt gtctccgcgc atttcattta ctcctttagc aacgactttc
    11341 aaagcatcga tatccagacc tgaatcgatt tcgtctaaaa ttgcaaatgt aggttctaac
    11401 atcaacaatt gcaggatctc attccgtttc ttttctccgc cagaaaaacc ttcgttcaga
    11461 taacgttcag ccatttcttc tggcatattt agtaaagcca ttttttcatc taactttttc
    11521 aaaaatgcca taacagaaat tttgtcgttt tcatcacgtt tcgcattgat cgctgcacgc
    11581 atgaattccg cattcgtgat acctggtatc tcacttggat attgcatagc taaaaataag
    11641 ccaagtcgcg cacgttcatc tacttccaag tctaaaacat ttttcccgtc aaacaaaatt
    11701 tcgccttctg ttacttcata gtttggattg cccatgatag cggcagataa ggtagatttt
    11761 cctgtgccgt taggtcccat gatggcatgg atttctccgg ttttcattgt taggtttacg
    11821 cctttaagga tttctttttc ctcgatcgac acatgtagat tttttatttc taagacagac
    11881 atgcattata cccccaaatt ctctttcgtt ctcactcatt ttagactaat tgagaatgaa
    11941 gcgcaatgac cttccttact aaaatcaaat atcttttatt tattattaaa caattttgat
    12001 ttctaaatta gaataggtat aaaaaagatg agaaataagc cattacagac ttatttctca
    12061 tcttttttgt tccatacctt attttgcatc agcctttact ggtttaacag agccgcccca
    12121 tttgtctgtg atccattctt ggacttcttt gcggtgaagc acttcaatca gttttttgat
    12181 tttgtcactg tcttcatcac ctttacgagt cgcaataata ttcacgtaag gagagttgtc
    12241 cttttcaagc aatacggcat cttctaatgg attcaaccct gcgccgtaag cgaagtttgc
    12301 gttgattgca actaggtcac cttcatcatt ttggtacgta gaagctaaaa gtgatgggtc
    12361 gatcgtatgg ttgaacttca agttcttagg gttttcttca atatcatcga atgttgctgt
    12421 ttccagatct actccatctt tgactttgac taagccagca tcttgtagaa ttgtgatgat
    12481 gcgtccccag tctgattcag aatttgaagt aatgattgtt gcaccatctt ttaattcgga
    12541 aacatctttg acttttttag agtacaagcc cattggttcg atgtggacag caccggcatt
    12601 gacaaagtca tatccttttt ctttgatttc tttgttcaaa taaggaatat gctggaagta
    12661 attggcatca atgtcgcctt cttccaaaga ttggttcggt aatacatagt catcgaattt
    12721 gacgatttca agatcgattc cttcatcttt caataatggt ttcacatgtt ccaaaatctc
    12781 tgcgtgcggt gtcggtgaag cgccgacttt caatgtcgtg tcgtctgctt tatttgctga
    12841 atctttgctg tcgctgttgt taccgcatgc tgctaatcct acagtcagca aaagcgctgc
    12901 tgcaaatcca aaaattttct ttttcatatc ctacatcccc ctatatccta ttatcttttg
    12961 tctgttttct tagttaagaa atcaccgatt ccttgaacga taaatacgat tagtaaaata
    13021 attaaagtcg caacgaatgt cactgttaga ttaccacgct ggtagccttc ctgccaagca
    13081 agacctccaa gtccacctgc gccgatcgcg ccggccatcg cagtaaatcc gatcatcgag
    13141 atcgttgtaa ctgttaatcc agaaatcaat gcgggaatac tttcaggtat caagaccttc
    13201 cagatgattt cccagtaact tgctcccatt gcatctgctg cttccagtac accagggctg
    13261 acttcacgaa aagcaatctc tactagacgg gcataaaatg gtgctgcgga taaaacaaga
    13321 gctggaatgg ctgcttgcgc acctagcata gtgcctacga ttgctttagt aaatggaatg
    13381 atcaaaacca tcaggatcat aaatggcgtt gaccggaaaa tattactgat gatcgatacg
    13441 attccataaa tgattcgagc atacggtttg tttttgcgtc caatagagta aaggatcaat
    13501 cccaaaacta atccgatgat cgtcactaag accattgaga ttaatgtcat atatagtgta
    13561 tcaaggatag cctgattcat cgtttccggg ttgatttgtt taaaatctag atatgtttct
    13621 gaaaagcttt tatccacgat ggatcacctc aattcctact ccttgttctt tgatgaacac
    13681 ttctgcttga tctaattctt tggtttcacc agtcatcaag acagtcaatg aaccaaagga
    13741 accttctttc acttgtttga tctttccata cacaacgttg acatcgatgt tatagcgtcg
    13801 aatcgcttgg gaaatgactg gctcgttggc atttctttcg ctaaaggtca aagttgccaa
    13861 acggccgctt ggattttctt tgatgagttc agctaatagt tctgtcgaat cagcttctgg
    13921 ttcgatgtct tgttgtacaa agcgtttggt tacttctttt ttcggttgtc tgaagacagt
    13981 caatacgtct ccttcttcta cgactttccc caactccatc acagcgactt tgttgcagat
    14041 tttgcggatc acattcattt catgtgtgat caagacgatg gtcaaattca atttcttatt
    14101 gatcgctaac aataagtcta atacttcttc tgttgtttgc gggtccaatg cgctagtagc
    14161 ctcatcacaa agcaggatct caggatcatt tgccaatgct cgtgcgatac cgacgcgttg
    14221 tttctgtccg ccggaaagtt gtgaaggata tgcttgtccg cgtccttcta acccgactaa
    14281 acgcaacagt tcttctgccc gttctttacg tttgctcttt ggtacgccag ctaattccag
    14341 cggcagctgg atattttcaa gtacagttct tgaccataac aggttgaaat gctggaagat
    14401 cataccgatt ttctttcgga atgtacgtaa ttctttgttt tttaattttg taatatcttg
    14461 atcgtttacg atcacttcgc cgctcgtggg aagctcaagt ccattcagga gacggactaa
    14521 tgtacttttt cctgcgccag aatagccgac gattccataa atatcccctt tttcaacgtt
    14581 tagtgaaacg tcattgacgg cttggatgtt tccgtttttc ccattgaatg tctttttgac
    14641 attcgttagt tggattaatg acatgccatt cacatctttc tcttataatt tttcaaacaa
    14701 aaaagccttc gccctcttgc cttaagcaaa aggacgaaag cttgaacttc cgtgttacca
    14761 ccttgattta ccgttacttc gcaataacag cctcttccag tacttggact tagcttcttt
    14821 ccgtatactg tcgcgctgta acgggcactc ccgtagtaag tttgcttacg ctcgcttact
    14881 ctgctctaag accatcttcc atctcatttt cgttacccat tttcagcaaa cagggctctc
    14941 ttcaaacgtc cgtgacatgt actcttcttt tcaaagcttt ctcgtttcat ataggattgc
    15001 ttatgattat agcaactgga agaatcagtg tcaacttttt tcaagtgatt ttctgatttt
    15061 ataattcgtc aaattctttt ggatcaacat ctttgaaact taagatccac gcattcattt
    15121 catctgaatc attcaagata ttgatatctt caccgatttt atcattaaca gaagaaactg
    15181 tacccgttag cgggctggca aattcattga ccgctttttc cgcttcaact tcgatcagag
    15241 gttcatcttt ttttagcgat tgtcctgctt ttggcagatt ggcaaacgtg atgtctccaa
    15301 gttcttcttg cgcttcattt gtcaaaccaa cacagtattc ttttccatta aataagatcc
    15361 aaaggttgtc ctttttcttc aaatgcttgc ctgccatttt atatcagttc tccttcataa
    15421 attttttcat tgaatccaat tgcaacaagc tggtcctctc gtaagatcag tggtcgcttg
    15481 atcagcatac catctgtcga taagacttgg ctcgcttttg aagccgtaaa ctcgcctact
    15541 tgatctttca gtccaagttc ccgatatttc atcccgcttg tgttgaacag gcgacggatt
    15601 ggtacttgac tcgtttctag ccaagtctca atcgttgagg ccttcggtac ttctttgatc
    15661 atatcaacgg tttgataact aacgccatgc tggtctaacc acgctttggc ttttttgcat
    15721 gttgaacatt tcgggtacca gtaaaaggtg tacaattttc ttacctcctt gaagatcttg
    15781 caggtgcttc attttggtat ctcatcgata atatcaaccc gataccgatc atgttcccta
    15841 aaatcgagga tcctccctga ctaatgaaag gcaatgggat ccctgttaaa ggaagtaatc
    15901 cgatatttgc tccaatattc tcaaagacat ggaacagcag catcatgatc aaaccgcttg
    15961 cgatataggc gtaaaattca ttattcgtat cgaaacacac ccgaatcata cgatagatta
    16021 aaataaaata caagaaaatg acgaatgcac caccgataaa gccgaagttt tcaccgataa
    16081 cggtaaaaat catatcggac tcacgaacag gcacatagat attgcttacg ttgaatcctt
    16141 taccaaacaa gccaccggta ccaattgcca aaagtccttg ggccggctga taactcattc
    16201 ctgacgtatc atggaaaggg tccagccatg aatcaatacg tgcaaactga taagatttga
    16261 atccaacttt ataaagcaag tctcttccgc cttcagtcgt aaccaagaag atcgttcctg
    16321 ctccaacgac tactgccaag attactacag gtgcgatgat gcgccaagag attccagaca
    16381 tcaggaaaat cccgccaaag atcgcaagaa agacaagcat cgttccaaag tcatcttggg
    16441 ccatgatcaa tgctaaaacc ggtattgtca cgatcaagag cttcccaatc agccaaaagt
    16501 ccgatttcat cgtccgttct tttacttgcg tattatgttt agttacgatc agtgccatca
    16561 tcaagatgta cgcaatcttc atcaactctg ctggctggaa agtaaacgca ccgaatcgaa
    16621 accagttttt agaccctgtt gaagcagcta aattctgatc atagaatttg agcaagagtc
    16681 ccattaccac taaccccaaa ccataaaggt aaggagtcag tttccagatc catttggaat
    16741 tcaaatgcat gatgacaacg attgctgccg ctccaactaa ataccagaca acttgcatcc
    16801 ctacgccttt caagactgct ggattgttcg gatcatggct aagtgctaca tataatgaga
    16861 gcagaccaat caaacataac agaaagactg gtaaaatcac gccataatca atacgattat
    16921 cgttcgaagc ttttaatttt ttttccatgt ttcatccctt ttcttaaaaa ccatactgct
    16981 gattattata gcggtccagt tagataatgg aaagtctttc catagacatt tgggaaaaat
    17041 taactttccg tttgtgcagt tgcttgagca aatgcagtac aaaagcctac tgcttatctt
    17101 tagtgtatca tagaactttt tttgatacat gcaattatct accagctgag attctcctcg
    17161 ctgtgagaag tttctgtgct ttcattgtat cgaaggatct cttcggcaat ctctagcagc
    17221 tgatcagaaa ccagattggt tcgttggatg aaataaaaat atcgatggaa attcaacgga
    17281 gtcattggca cattttctgg aacagagcgc ttagacaaaa tcgagcgacc gattccttcc
    17341 ttcagcaacg caacaattac atcgttactt ttcacgatca tcttcttatc ttggatattc
    17401 atctcttcaa aataacgctg cgtgtaatga aaaacaccag agtttgcttc tcttacaagc
    17461 cacaatttgc tttttgggtc cccagcgatg actagctggt cttccatcaa agagtatctt
    17521 tgtacgccgg aagtctctaa tggcttttcg ataaaaccaa aatcggattc atgtttcgct
    17581 acttgttcta atgattcatg agaattcgtg atttcgatct caaaatgcac tttaggaaac
    17641 cttttgatca gatgtttcat caactgaggc aaaagataga cagcaaaggt gtgggaagca
    17701 acgatccgac atacttcttc ttcattttgt tcattgagca atttttgctg agtttcttcc
    17761 cattcttcta acaaaaccag tgtccgttca tataataagt cggcttgctt agttggaagc
    17821 atctcttttc ttccgttacg ttgaaaaaga tcgatattca attcccgctc caactgtttg
    17881 atttgattcg agactgctgg ttgagataaa aacagtactt ctgctgctct ggaaaaattt
    17941 cttgtttcat atactgctcg aaaagtcgtt aataacttaa acatggcacc acttccataa
    18001 ctttttatga taattactat aaaaactatt tgatttaaat atacaaaaaa ccatctataa
    18061 tagaaatgta caacaaaaca gttgctgatc caactagtaa cttagatgaa gacaatcagc
    18121 tgtctgcttg ctcgtaatca tacattccta ttcattttac aatgtattcg ttcatcttgg
    18181 tactaaaatc tattaaataa aaaggagaat attatatatg aagaactttt tgaaaattat
    18241 tccgatcccg atctgcgggt tgatccttgg gttagcttcc cttggaaatc tgtttaaaga
    18301 ctatcaccat gttgctttag gcaatctaac tggcggtatc tctatgattc ttatgatatt
    18361 catttttgtt aaattgttta tcttattcga acacacgaaa caaacgttgc atgatccaat
    18421 catcgcctcc gtttcaccaa cttttacgat gtcactcatg gttatttgta cttattttgt
    18481 ttcatatgaa agtattgcac caattgtcaa attcatttgg ctgtgcgctg ttatcttcca
    18541 agtgatcctt gtcttttatt tcaattatca ccatgttatc aaagctgatc tttcaattga
    18601 agcaatttat ccaagctggt ttatcattta cgttggattt ggggtcatca ctgtaactgc
    18661 cgggaacttc ttcccactta ttggaaaaat tttcttttgg atttcattga tctgctatgc
    18721 gttcttattg ccgatcatca tcaaacgtgt ctttttcgta agaaatatgg ctcatccgac
    18781 acgtccgctg attacgatcg ttgcagcacc tggttctctt tgcctaacag gttatcttaa
    18841 aaactttgct gaacctaatt tttatcttgt cgtagcattg ttcgctttat ctcaagtatt
    18901 gtatttcgtt gtgctgtcta tgcttccacg tttgttcaag cttcgttttt atccaagcta
    18961 tgcagccttt acattcccgc ttgttatctc tgcaacagct atatttacta ctgttcatta
    19021 cttcaacagt ttaggtatct atagtagcgt attggatttc ttaaaagttg cggaatgtct
    19081 gtttgcaagt gtagttgtct tctacgttct tgctcattac gtacgtttct taattaaaga
    19141 acatagcaaa catggaaaat ttgtttctaa aaaaatcgct taataatcga ttcaataggt
    19201 tgtgaaaaag ctgttctgca tcaagtaata agaacggcca aacaaaaaca gctgttcatg
    19261 tttttgtact ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaccaaga
    19321 ggtcgtaaaa gaagtggtca gcttcaagaa ataagaagga atttacgaaa attgcttctc
    19381 aaatttttgt gaaatttcgg cttatttccg tagaagctac ttctggaaca ccgtttattc
    19441 gaaacaagag gtcgtacaag acttttgtca cgacctcttg ttcttttgtc aaaatactgg
    19501 tttagtgcta ctatgttcga gtatgctttt agtatttatt gacgaaagga accgatcaaa
    19561 tgaaatcatt gtcacatcca ataaaatctg taaaggattc agcggtccgc gaaatcttac
    19621 ccggtttact gctttctttt gccatcgctg ccttcagcag gcttcttgct atttatctgc
    19681 cacagttagg tggagcgact attgctattt tattgggtat tttattagga aatacttttt
    19741 ttaaacagcc tgttctagca atcggcacaa aatttgctga aagcaaacta ttagaattct
    19801 ctgttttttt actaggtgca actgtcacag ctcaaacgat tgctcaaatt ggtgtaaaag
    19861 gaattgtttt tgtgttactg caaatgtcag tcactatcat cggtgcttac ttgattggta
    19921 aaaaactgca attcagcgat acttcttctt tgatgatggc tggaggaaac gctgtttgtg
    19981 gttcttctgc tattgcttca atcgcccctt ccatccatgc gaaagaggaa gaaaaaggac
    20041 agatcatcac actagtcaat ctactgggta ctgtgatgat gttgactctc ccttttcttg
    20101 gattacagtt gtttggtgga aatctcattg aaaaaagtgc acttttgggt ggtacactcc
    20161 aatctgttgg tcaagtagtc gctggggcaa gcttacttga caattctgtt gtcgaattcg
    20221 ccatgctatt taagattcta cgtattatga tgctcgttgt tgttgtctat ctgtttgaaa
    20281 aattcatgca caagaaacaa ccagctctgt ttgaaacgcc aactgatacg cagaaaaaac
    20341 gaaaattacc gcttccttgg tatgtattag ggtttgtgat cttttgtttg gtcaacagct
    20401 tgttttcttt acctgtagtt attgaccaat cggcacattt tatcagcagc tggtttgaga
    20461 tcactgcttt agcggcaatt ggtctgcgtt tagactttgc aaaattcatg aaagaaggta
    20521 cacgcttctt atcttatgga ttagctgtcg ggcttctcca aacagtgatg gctttactat
    20581 ttatttggct gatcaaagtt tagaatgaac atgaaaaaac agttgtgatt ctcgcatgga
    20641 acaatgtccg aatcacaact gtttttaatt ttgcagatat ccttctaaca acaacaattg
    20701 gcgtttgatt tcaaccccat ctattgcgtt tcccatatat cctgtcagtt ttccattttg
    20761 cccgatcact cgatgacaag gaataacgat tggcaatgga ttggttcgat ttgcctgccc
    20821 aatcgctcgc acagctttcg gactatcaac agcaacggct acttctttat acgttcggat
    20881 ttctccataa ggaatggtcg acaaagcttt ccagacattt tgctgaaaag gcgtacctct
    20941 ctttatagat aaaggaacat caaattcttt tctttttccc gcaaaatatt cttcaaactg
    21001 ttcttgtgtg cgcgttaaaa ttcgctgatt cgctgattcg ctttctgaaa ttggctgaaa
    21061 agatacagca gtcaatccgg attcatctgc atctaaccat aaaaagccga taggtgtgtg
    21121 tattttcatt ttgtttgctc ctagtcaata gactggaact tcctcctttt tctctatcca
    21181 aaactacttg ccaactaata aaaattgttc ttaaaagttt gataaaccga ggaaacatgg
    21241 taaactaaat acgttagttt acaaaaagaa tacctgttct tttacgtaaa atcaaatttt
    21301 aaaggtgtta tttaaggttt attaaatttt gaatgtaaac catatataaa catacgattg
    21361 aaaggataga aacgatgaaa gtatcaattg ttgtcccatg ttttaatgaa gaaaaaactg
    21421 ttcctctttt ttttgatgag gttgaaaaat tcaaaggtgc ccatgagttc gaatatttgt
    21481 ttattgacga cggatcaaaa gacggtacgt tagcagcaat caagaagcta gcctcagctt
    21541 atccttatgt ccgctttgtc tcattttcca gaaattttgg gaaagaagcg gctctgtacg
    21601 ctggattgca agcttctaca ggagatttag tgaccgtgat ggatgttgat ctgcaagatc
    21661 cgcccgaact gcttcctgag atgatcaacc ggatcactac ttctgatatc gattgtgtcg
    21721 gcacccggcg ttcgactcgt gaaggcgagc ctgcgatacg cagtttcttt gcgaaaaaat
    21781 tctaccagtt gatcaataaa atcagcgata cagaaatggt cgatggcgct cgtgatttcc
    21841 gcttgatgac tcgtcaaatg gtggatgccg tcctagaatt aacagaatac aaccgatttt
    21901 caaaaggatt atttagctgg gtcggattta aaacagaata tatttcttat gaaaaccgcg
    21961 aacgtgtggc tggcgaaaca tcttggtcct tctggaaatt attcaactac tcgattgatg
    22021 gtatcgtgaa cttctcggat gcaccgttaa cgattgcttc atttatcggc gctttgtctt
    22081 gtgtcggttc tggtattgca attttgttca ttattttgcg ggcattgttg tttggtgatc
    22141 ctacatcagg atggccttcc atggtctcga tcttcctgtt cattggtgga atccaattgt
    22201 tatgtcttgg aatcatcggg aaatatattg ggaaaatctt cttagaaacg aaacagcgtc
    22261 ctgtttatat cataagagaa acagaaaaag tgaagccaaa tgaattgaag cctcaccaat
    22321 aatatacgtc aaatgaagta aacatttttt taaatgaaaa aggactgtga caaaagtctt
    22381 gtcacagtcc ttttttccga ataaatggtg ttccagaagt agcttcttcg gaaataagcc
    22441 gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt cttgaagctg
    22501 accacttcta tcacaacctc tttcatatct tattacttct tcattgctgc ttttagtgct
    22561 gctgctaatg ggctttcttc tggttcttct gcttgtgcat attttttcag caagcgtcgt
    22621 tcttcatgtt tggtcatttt cttcttctgc tcttttttat caagcaattt ttctgtcgtt
    22681 ccatcgtatt tacaacggaa ataagcaccg tttttacctt cgatgatttc cattttccgg
    22741 tgacattgcg ggcatcgatg attagagact tttggatctt ttcttctgcg gtagttgcaa
    22801 tctgaattgg tgcagacata gattttgccg tcacgtgtgt ttttctcgcg cagattggcc
    22861 ccacattctg ggcatttctt ttgggtaatc gagaaatctt gatattcttg tttgcttgat
    22921 ttgatctcat tcaccaagcg ttttgtttct ttttcgattc cattcaagaa ggttcctgct
    22981 tgtttctttc ctgcagcaat agcttcaagg tctttttccc agctttctgt caaatctggt
    23041 gttactaaag agggatttac caatactaat aattgcttac ctttaggaga tacttgcagt
    23101 ccttgagggg tacgttccat cagttcagat ttgattagtt tctcgataat ctctgcacgc
    23161 gtagctgggg ttcccagact gtatttttcc atttgaccaa gcaagcttgc ttctgacaat
    23221 ggtttaggcg gtgcagatag ttcttttttg atggcgaaat cgggattgat tctcattcct
    23281 ttttcccatt tgactgtttc cgtctcagtt tcagtttcgc ctttccatcc tgcttggacg
    23341 acacgatttt gccgaaaaat gaatcgttct ttaccaaatt caaccgtaac ttttgtttgg
    23401 ctgactttat ggggttgagc aaacagtcct aaaaaacgag agacaatcat ttgatagatt
    23461 tttcgctctt cattacttaa tttttcataa cgtgctctgt tttcagttgg caaaagtgca
    23521 tggtgatcgg tcactttact gtcttggaat acttttgtct gttggacgat ggctccgttt
    23581 ttcaaatact gcttgacctc aggagcaaag tcgctgactg cttgcaatcg ttctttcatc
    23641 gtacttttca tgtcatttgt cagatatttg ctgtctgtac gcggataagt aacgatctta
    23701 tgggtctcat acaaactttg tacaagactt aatgttttct ttgcagaata gccatagcgt
    23761 tgattggctt ctctttggat ctctgttaaa tcataaggca atggcgcaga ttccgttttt
    23821 aatttttctt ggacttctgt gacagttcct ttgcttgtac tgatcaattg aacaagtttt
    23881 tgtgcttctt cttgtgtttt taaagcaaat tgattttttt gaagcatttt ggcttgttct
    23941 tttccagctt gcaacgtgat cgtgaaatac gtttgtggac ggaactgctc gattttcttt
    24001 tcttggtctc tcactaatgc tagtgtcggt gtctgcacac ggcctgctga taaattatcc
    24061 gcgtacttca cagttaaggc tctggtcaca ttcaatccta ccagccagtc cgcttttgcc
    24121 cgggcaagag cagattcata caatgcatca tattctttcg caggtcttag ttgcttgaat
    24181 ccagttttga ttgctttatc tgtttgagaa gagatccata accgcttcac tggtttattg
    24241 aaatgcacat actctaagat ccagcgagca acaagttccc cttctcttcc ggcatctgtc
    24301 gcaatgactg cttctgagac atcttttcgc tgagccagct gcttgattgc ttttaattga
    24361 tgtcctgttt taggaagtgg tttgattcct agttttttag ggatcattgg caacgtgtcc
    24421 atttgccagc tctgccattc cttattcaga tcttccggca ttttcaatcc taataaatga
    24481 ccaagggccc aagtaacgat caccttgggt ccttcataat aatttttgtg cttttgatta
    24541 gcaccaagca ccttgcttag gtctttcgca acgcttggtt tttccgctag aattagttgt
    24601 ttcataaaat tcctttctgc tttctactgt gatgggctga tgatttttca acaacgcaag
    24661 tcccttgtat tgctgtaaat catcgtcaca ctcttcacac cagcgctcat ctccgtcatt
    24721 ccaaaaggcg ctgagaaagt tactttttgc attgatatat tcataatttt gatggatttc
    24781 gttccattgt ttttcgtacg cttgtcgtgc ttcttcgaaa gactcgaatg tttcttcttc
    24841 ttcaatatct tcttcccagt cttcaaaaaa ccaccaaggc tcattgtccc cgaacatggt
    24901 aattacttga tacatactcg tgctccttct ttcagctttt ctagactcat cttagtcact
    24961 tttcaagaaa gttgcaagaa ttttctctta taaaagggtc atttaatgaa catcttaaaa
    25021 ttgttacaaa tgaatctgat tgtttaaggc aaagtagcga taaagttatt gatcatccaa
    25081 aaatagctgt cttctggatc gattgttggt tcttttgtaa agtatcctaa aaaacgtaag
    25141 gaaagataac cgtggatcat actacgaagt tccctgcttc gatgaacttt ttcttctttc
    25201 gttaattgaa aagcctcaaa tatctgcaaa atgatctgat tcgtttcatg gattccatct
    25261 aataaaacag cttcattggt atgcggtaca ctgatcagta actcatacac tgcttgattt
    25321 gaaaaagcaa aggatcgata agtttctgca tagatctgca gtgcttcctg accacttttt
    25381 cccacaagag cccgtcgcag ctggtcatta agttcctgca gaagtttcgc tgttagcgct
    25441 gttttgacat cacgaatatt tttgaaatgg ttatacagcg agggagcctt gatatccaag
    25501 cgtttggcta aatgctgaaa ggttatttgc tgaacatcca tctcttctgc tagttctcga
    25561 aagcagtcga tgattttctc ttgagacaga tttctttttt tcatttccat gtttcctctc
    25621 ataaaataaa tccttcactc tttcagttta ccacgaaaaa gaaagagaaa aaagagactt
    25681 tcattgataa actacatatt gtagtttata ataaagagct gtagatgaaa attttcagaa
    25741 agaaggagtc taattggctg caagaataaa ggaaaaatta tttaggaaaa gagaaacttg
    25801 ggaacaaaac ttgtttgtct tatggtttgg aacatttatg gctggtatcg gatttagttt
    25861 agtcatgcct tttatgtcac tttacataga tacgttaggt aattatagta cgtcacaatt
    25921 gaacttttgg agcggattga ctttttcatc tactttcttg gtgactacgc ttatctctcc
    25981 ttggtgggga aaattagccg accaaaaagg aagaaaattg atgctgttgc gtgcttcatt
    26041 aggaatggca atcgtcattt ctttgatggg ttgcgtgact agtgtgtatc aattagtcgc
    26101 attgcgtctg cttcaaggga ttttttctgg ttatatcagt aatgccactg cccttgtcgc
    26161 aactgggacg ccaaaagaaa aaagtggtca agttcttgga accttagcaa ctggttctgt
    26221 tacaggaaca ttacttggac cgcttcttgg cgggatctct gcttcagcgt ttggctatcg
    26281 ccctaccttt ttcattacag ggatcatctt atttttcgtc ttcttgttga gtctgttttt
    26341 cgtccatgaa aaatttgtcc cagtgaaaaa agaaaacatg gtttctgcca aacagatttt
    26401 caaagacttg aaatatccac acgtcgtcat cggtatgttc gtcacaacga tgatcatcca
    26461 agcatccaac aattccatta gtccaatcat cagtctgtac attcgccaat tgctgcatgg
    26521 acatgggaat gttacgttga tcagcggaat cattgcttcg atacctggga ttgccacttt
    26581 gatagccgct ccaagatttg gtcgcttagg tgacaagatt gggagtgaaa gaatacttgc
    26641 gattggtttg ggttttgcga ttctggttta tatcccaatg gcattcgtca cgaatgtttg
    26701 gcaattagct gccttacgtt ttttgattgg tatctctgat gcttgtctgc tccctgctgt
    26761 ccaagcattg atcacaaaat attcgcctca tcaagctgct ggacggatct tcagttataa
    26821 ccaatctttc caagcaactg gtaacgtagt agggcctatg atcggctcca gtgtttccag
    26881 tgcatttggt tatcgcggcg tctttctttc gacttctctt cttgttttgg tcaacttctt
    26941 gcttgtacga cacaatacac aagagatcca tcagcaagaa actgcagaag aaaaagcttc
    27001 aggagtctcc atagcttcag ggcactctcc ttctcataga caataagcgt aaatgaaaaa
    27061 cactgcttga acagttgtca cagactgtcc ttgcagtgtt tttgtttagg cctgtttttt
    27121 caagaactca gataagagga ataatccctt ttccaaggtt tcttttttac aacagtaacc
    27181 tagtcgggca tgcttcggta aatcaaaggc acttcctggt actaatagta ctcctgtttc
    27241 ttctaataaa ttgatacaaa atgtctggtc atcttcttcg atggctaatt taatgaaaga
    27301 agtagagacg taattgggag cgacaagttc aactttcggt tcattggcta cccattgttt
    27361 taaaatcaca aggttctctg taatgatctt tttgtttcgc gccaatattt tttctttatt
    27421 cttcaatgca tgtacagcaa gatcatctga caggactccg ccgcaaatca tcgtgtagtc
    27481 tcgatacttt cgaaaaactt ctgccaactc aggtccagta gctgtccagc caatacgaat
    27541 acctggaatg gagtaggttt tggataggga attggttgct ataccttttt catagacatc
    27601 tacgatcgac aagaattcac ctttatccgt taaaggcgca tatacttcat ctatcaatac
    27661 atatgcatct actgtacgag caatttctgc gattttttct aaagttttcc gatctagcaa
    27721 tgtgcctgta ggattgtttg cactattcaa acagatgatt tttgtttcag gtttgactaa
    27781 ggcttctagc tgttctaaat caaactgcca atcttcttct tccttcaaat gaacaaagtc
    27841 aacagcggca cctaaagatt tggggatgtc atataattgc tgataagtag gaagcatcga
    27901 aacaacatgg tctcctgctt ccactaacgc gtatagagct aaaagattag caccagtcgc
    27961 tccattcgtt tgtaagatgt tttccggatc gacggtttga taaagagaag cgacttcttg
    28021 tttgaaaaca tctgatcctt cgatccagcc atagtccaat ggttcgtttt tgcgtttttc
    28081 gaaaaattta cttacgctag tcccatctaa gccaacgagt tcgtctaatg tcaatgcttc
    28141 gatcgagctt tgtgcaatat catataccgc tttcttttcc catttattta gccattcttc
    28201 tacaccgaaa tttgcgattt tcatgtttct ttccccctta tatcttgatc cagcctacag
    28261 caagcaaccc gattgaaagc agtgcggcca cacaaatcag cccaatcatt actttttctt
    28321 ttcccgtaat ttgatgtttg gtttcacgac aagcgatcca gtagaagcaa aaaccaggaa
    28381 gataggcaat actacataaa aggacataag aaaatcctgc taaaatgatg cccatcaatt
    28441 caaaaactac agcaatccca ccgatcacta cttgtttttt gattccttct tttaaagaaa
    28501 actggacttg atagatcccg acaagtagat aacaaatcaa aattgccgct gtacataaag
    28561 aataggcaaa ttgataggca taatcagtaa ctaagaaagt caataagaat agattagtca
    28621 agattgcagt aacaactaac gaataagttg gggcattttt tttattcgtt tttccccaac
    28681 ctttcggcaa cagaccgtct cgagccatca acatcgttgt ttctgctggg agcatcgtcc
    28741 aagacaacca agaaccaatg atcgaaataa tcaagccgat attgatcagc gctgctcccc
    28801 aatttcccac gattcctttt aaaatatttg ccatagcagg ttgtgaaata gttgctaact
    28861 cttcttgaga taagacgccg tatggcaaga tcgaagcaag gatatagata aacaataaac
    28921 aaagcagacc aatgatcgat gcttgctggg cttctgaacg tttcttcgcg cggttggcta
    28981 aaacacttgc gccttcgatc cctacaaaga cccacatcat aaccatcaaa caacctttaa
    29041 tctgcaacca gatcgttcct tgctgccctg ttccattcac tagattatca gatacgttac
    29101 cccaaaaatc agcagtgaat atattcactt taaatgcgat aaatacaaat attaaaaata
    29161 ggaataatgg cactaattta cagatcgtca cgattgtatt gatgacgctc gctccttcaa
    29221 ctccattgtt tactaataaa gtcagacccc aaataaaaat acttgcaaat aaaatagaag
    29281 gaacattttg tccacctttg aatatcggga aaaattctcc catggcgctc atcagcatcg
    29341 ttgcaaaagc aacatttccc agccacgcag acaaccagta accccaacca ctgatgaagc
    29401 cacctaattt accaaatgaa gcttccgcgt aaccgaaaat accaccatct agatctggac
    29461 gcttttctcc taaatgattc agcgataata ccaaagctaa aataccaatc ccaacgatta
    29521 tccatgaaag gatcgctggc cctggagctg cagaactagc cagatcactt gtgatcccaa
    29581 acacaccgct tccgattgac gaactgacaa ccagagcaac cagtccccat ttgctaatac
    29641 ccgtcgattt cttttccatt tccatcaccc tcacttataa aattgaacaa atcacttgca
    29701 aaagattccc ttctattttg caactgctct tgcttaacaa aaagcaactt tattcatatt
    29761 attggatatt atgaactttt tacacaagta tttcaagtat aaaatgaata aaaattaatt
    29821 ttattgcaaa aaaacagcta tgctatccaa aagaaaaggt gtttcttttg ttagccatag
    29881 ctgttttgat tcatttaata tcgcttaaac gtattgtaaa acttttgttt cttgatatgc
    29941 gtggtcgatc aaaccaccac ccagacattc cattccatca taaaatacaa ctgcttgtcc
    30001 aggagtgatt gcacgtacag gttcgtcgaa tacgacttct gcacgattat catccaataa
    30061 gcgaactgtc acaggaacgt cttgctgacg ataacggaat ttcgctgtac acttgaattc
    30121 ttttggcatt ggttcattcg tcgtaaagtg gatttcactt gcatccaagc ttgtggcata
    30181 caatgcagga tgatggaacc cttgccccac atataatgtg tttgtcgcta gatcttttcc
    30241 tacaacaaac cagggttctt gcgaatctcc tccgccaccg atccctagtc cttgacgttg
    30301 accaatcgta taatacatca agccagcatg ttgtcctttg acttcaccat caagagtgac
    30361 catatttcct ttttttgctg gcagatagtt gctcaaaaat tgtttgaagt tcttttcacc
    30421 aataaagcag attcccgttg aatctttttt cttagcagtc gcaaggcctg cgcgttcagc
    30481 aattgcccgt acttctgatt tttccatgcc gcctagaggg aacatcgttt ttgaaagctg
    30541 ttcttgtgat aattggctaa ggaagtaagt ttgatcttta ttattgtcta ctccacgaag
    30601 catgtggacc acgccgtttt catcgcgagt gacttgcgca taatgtccag tagctacata
    30661 atcggcgcca agatccattg cataatccaa gaatgctttg aatttgattt ctttgttgca
    30721 catcacgtct gggttaggtg tacgtcctgc gcggtattcg gctaggaaat attcaaatac
    30781 acgatcccaa tattcttttt caaaattcac agagtaataa ggaatcccga tttgagcagc
    30841 tactttcgct acatccttat aatcttccgt ggccgtgcat acaccgtttt cgtccgtgtc
    30901 atcccaattt ttcatgaata ttccgatcac gtcgtatcct tgttccttta acaaaagtgc
    30961 tgttacagat gagtcgacac cgccgctcat ccctacgaca acgcgtgttt tgctgttgtc
    31021 tgtcatgata tcaccatcat ttcaattaga ttctgaaaca tctacgagtt gaaggtcgca
    31081 acttttcagt attttacatt atacgtcata tttctgaaaa tttcatccct taattatcaa
    31141 gtcgtaaaaa tactgttcta ctggacctat tcagtacaca aacatgatag tcaaccaaaa
    31201 aatcactcat cttttgagca ttcgatataa aaaattggca tactcataaa aagggccagc
    31261 ctttcggcaa taaggaataa ttttataaat tgtgaaaaac tatttttcaa aattgcttct
    31321 tatcgcttaa agctgcacgt ctcatttaca accttttctt tttagatgtt atgagttgct
    31381 cagataagtg attttgttta ctctaagaaa aaagggaggc aaaagataca tgaattactt
    31441 tatcagtgat atgcactttt tccatgaacg cttattagga aaaaacgact ttgctccgcg
    31501 gctctttgca aatgtggatg aaatgaacca acagttgatc actagctgga atgcagtaat
    31561 aaaagaaacc gaccatgttt atcatctagg cgaccttgct atgcatccgc aatatgaaaa
    31621 agcaaatgca gaaattttgg aactggtcac tcaactgcaa ggaacaatcc acttgatcaa
    31681 agggaaccat gacagtcgcg cttttttccg ttatttagaa aaaaatgatc ctaggcttac
    31741 tgacggaagt cccaaatttt atttttatga tgtaggtgcc atcgttaaat tcgaccatca
    31801 acaatattac ttgactcatt atccgatgtt gctcgggcct aacgacacta tccgcaatct
    31861 tcatggacat atccatcatt acagcgtacc tatcgagaac gatgtcaatg taggcgtaga
    31921 cgcaccggaa agagaactct taaaggaaaa actaccattt ggcactccgt tatctgagca
    31981 acaaatcaaa gaaatctatg aagcaaagag gaagtacgat aggtcgtgaa aaaactgccc
    32041 tatatcaagt attaaacaaa taaagataat tactcatatt tttcatttga gtaggcttat
    32101 tgccacagga acattaggat cagaaatgga gttgtaacaa gacttctgtc acaactccat
    32161 tccatactat tcgtcttttt gctcatggtg ttcttttacc agttttttct gtaattcttt
    32221 atcataattt cgggcagctg acgttaaaaa taaaacgatt ccgcataata aaatcccgat
    32281 tccggaaaac aagaacattt tttctacccc taaacgatca gctaatggtc ctgcaaataa
    32341 taatccaatt ggacctgcca ggttcatcaa agagttgaag ttccctaaga cacgacctaa
    32401 aacattcgat tcataactct gctggatcat tgccatcagc agtgtattga aatatggcgt
    32461 tgcacaacct gctcctgcat tcaagataag aaagtacaag aacccttgac tatcgtttgg
    32521 aaccaatccg cttgcaccga tcgtcaggcc cataatgatg taggctataa taataggttt
    32581 cattcggtct ttccatgttc ctataaaact gatcagtgca ccgcctaaga gcattccgac
    32641 tgcgtagact acttccactg ctcccgcctg tccaacggaa ccaccaaagt aatctagcgt
    32701 catcaatgga tacagactga ttgctggcat gaacaacagc atcacaaatg caccattgat
    32761 cgttatgtac cataaccctt tattatccat caattgctgc agcccaaatt ttgcatcttt
    32821 aaaaatagta agcggaactt ccaatatttc aggagaaact tttgggatct tcacaaaaat
    32881 caataagccg acaccaaaaa ctgcccccaa tacatctaat aaaataaggt aattgacagg
    32941 aacgactgaa aacaaagccg cacctagagc tggcgcaatg atgaaattcg ctgattggac
    33001 cattcctaac tgtccattcg tccttgttat gtgagaagat ggaacgattg tcggcataat
    33061 cgactggatc gttggcattt ggaatgtttg tgcgaccgaa cgcataaaca aagacacaaa
    33121 aactagccaa atcgggaagg attctgaaat cgttccgact actgctaaaa taagcgcgaa
    33181 aatcgctaca ataatatccg tgacaatcaa aagagctttt ttatcccagc gatccactag
    33241 cggtcctaca aatgggctta gtaaaaccat gggaatcatt cctagtaaag tagcaaaact
    33301 caaaattgtc gccgaaccgg tttctcttgt caaataccag atgatcgcat attggacgac
    33361 catactagtg attcctgaca aaaactgtcc cgataaaaag aacaaataat ttctcttcca
    33421 attcgttaaa acgaccgact gttcattttc cataaacatc cctcttttct ttttcatttt
    33481 gtatagcgtt tgcacaacaa tcattatacg ggattctttt ttcaaaaaat acctttttcc
    33541 ctaaataaca atcgtttcaa tttaaatttc tttacttaga aacaataaat cagcaaaata
    33601 ttaaaaataa caacatgtgt taaatttaaa aataaaaaag acaactaatt tgcgtcgtcc
    33661 ttacaaagtt agtcatctaa caataggccg tttcaaaact agttgtcttt ttatatccac
    33721 agatcattcg actttttcga ataacccacg gctaatcatc ccatccatca gaaaataaaa
    33781 tttatcttgg ctcattttct gttttggatc tttgaaaata ttgactgctt tcaatccatt
    33841 tgctgtagtg atcgacattt tcaatgtttg aatatctttt gatacagtga tttttaattt
    33901 gaatccttct ttgctttgcg gcgtggcatc taatggtcgg atcaattgat aattgcctcc
    33961 gtttgtttct gtaaatccat tatcgcgcaa tgtatatctt tttgcatcag gatgcaaacg
    34021 atagctaatt ggtgcgccca gtaccgttgc tgttgtttca aatgccatga ttttcacctc
    34081 gataaaatta gtttctcttt attataaaag tttatcctga tttttactag gtttttcagt
    34141 taagttccct aaaaaatgaa ggcgttctct cagacatctg ttcatataag aatgacttca
    34201 ctagttattt tttgacagca cgaactaatt gatcaaggaa atactggatg tcgtcttcgg
    34261 tatttcccaa accaaagctg atacggatgg attcttttag tatcggtgta tcttctccat
    34321 acattgcttc taatacgtgt gaaggctcga tatttcctgc tgtacaagct gaaccagtag
    34381 aaatagcgac cccattaaga tcaagcttca tcagtagcaa atcatttgct tcgccaatta
    34441 agcgaagatt caacacatga gggagtttat tcgttaaatc accatttact tgataaggga
    34501 tttcgtttgc ttctaatgta tcaagaatca attgctggaa tcctttatat ttgttgttac
    34561 gtgcttcacg ttcttcaggt gacagcagtt caactgcttt tgccataccc cagatccctg
    34621 ctaaattttc tgtacctgca cgccgctttt cttcctgctc cccgcctaaa agcaatgcag
    34681 ggatatttac tccgtctcgt ttatataaga aaccgacgcc ttttggccca ttgattttat
    34741 gagcagagat acttaataaa tcgattccta attcttctgg atggatcgtt tggtttccgt
    34801 acgcttgtac cgcatctgta tggaaataag ctggatgatc cgctaaaagt tcaccgattt
    34861 ctttgattgg catcaaattt ccgatttcat tgttcccgta catcacagag accaagatcg
    34921 tatcttctcg taacgctttt ttgacctctt cgatcgacag attccctttt tcatctacag
    34981 gcagatatgt aacgtcaaac ccctttgtct ctaaatattt catggtatta agaacagcag
    35041 gatgttcgat agctgtagtg attagatgtc tgccttcttt ttgacgcgag aacgctgttt
    35101 ctaagatagc tgtattatcc ccttctgttc ccccactgtt aaagatgatc tcgtgaggtt
    35161 ttgcttgcag actgtctgca atgatttgtc ttgctgtttc caatttttca tgcgcgtggc
    35221 gaccaaatcc atgtatgctt gaaggatttc caaacgtgtc ttgcatgatt gccgtcatcg
    35281 cttcaattac ttgtggatgc atgggggtag ttgccgcatg atccagataa atagttttca
    35341 cttcattcat cccttccaaa ttattgctag gcacattcta gcataaaata gcgaacaaac
    35401 caaagaagag ctcatttttg tctagaggac gtttcatggg catagaaaaa aggagctgtg
    35461 acaaaagtct tgtcgcagct ccttgaagct gctcacttct gtcacaactt ctttccctct
    35521 tttttttgtt tattcgaatt ctttttcttc cagacggaat aacggactca tcggtgtatt
    35581 ttcatggatg cgtttgaccg cttcacccat taattctgaa catgtaacga ttgttaagtt
    35641 ttctggatga cgattttctt ctgtgaaaac agaatcagtg atacaaatat ctttgattgg
    35701 tgcattgtct aaaatacttt tcgcatgatc ggacaataat ccatgtgacg cacaggcata
    35761 tacttctttt gcgccgtttt cttttaatac atttgctgct cgtgcaagcg ttgctcctgt
    35821 gttcaagata tcatctacca tgatacatgt ctttccttga acatcaccga tcacataacc
    35881 accctcagtt gaagcatcat ctgcatgatc tacgatggct aatgtgctgt tcaaatattc
    35941 tgaaagacta cgtgcacgct gaacaccgct gttttttggc gaaacaacta cgatgtcatc
    36001 tcccgtcaga cctaattgac ggtaataatg agcaaacaac ggcatcgtaa ataaattatc
    36061 tacaggaata tcaaagaatc cttgtacttg aaccgtgtgc agatctaaag tcagtactcg
    36121 agttgcccct gcttcttcga tcaagttagc gatcaatttc gcagtgatcg gttcatgagg
    36181 tttcgccgtg cggtcttgcc tagcataccc atagtaaggc aatacgacat tgatcgtttt
    36241 cgcacttgct cgcttcattg catcgatcat gatcagtagt tccatatagt aatcattgac
    36301 aggtgcattc gttgattgaa cgatatacac atgatcccct cgaatacttt cttcgatatt
    36361 gatggaaatc tcgccatcac taaattgctt cacgacgctt ttacctaatt ctgttccgaa
    36421 cactttcgcg attttttcag ctaatggacg gttgccattc aaactaaaaa tcttcaacgt
    36481 gtcatcctga tacttattac tcatgtagtc ctccccaaaa cttctctatt cttcgatagt
    36541 ttaacatatt tttccaagat tttctgttaa tttcagcaaa ttcttaagga agtgaaactg
    36601 ttccgttact ccaactggca ggaatgactt tatgataatc gccccagttg tcgtgtactt
    36661 tgtaataacg ttctcctgtt tcagtttcaa aataagcgta cgctgtcacc caatgattgc
    36721 catatgtact gccaagtact ttcaaaatac caatcatcac aggtttgcct tcacgtatac
    36781 gttttgtagc tcgctgccat gaacctagaa gagttgctcg tgcacgctca tgattgccat
    36841 tcttctttaa aaaactagaa atccctgtac taacctgaaa aggaatcgta ggaagtccta
    36901 gtggttggat ctggctacgc aatgccttcg tcaaaaccaa cgaatcagcc gtatttttct
    36961 tgcgaatctc atttggaagc atccacccct tacgatagtc ttgataatag gcaaggagaa
    37021 ctgctgccgc gtaagtacca caaagatagc ctgagggggt agcccatttc ttatacctca
    37081 aaaaacgttc ttctggcaat cccacccagc aatttgcgag ttcctttcct gacctttttt
    37141 cttcgatcaa aacgggaata tcttcttttc tgttgatcca tctagataac tcgattggct
    37201 cttcattgat cagcttccat tttttacaag aaagaccctc ttgataagta tattttgctg
    37261 gagaatattc taccggatgt cctgattgat cgataatcac ataactttga tcttcaaaaa
    37321 ccagagctaa aaaaagcaat ttactttttc ttgactgcag ctgctgagtg ctggctaatt
    37381 ttttaatttt tttatctact ttgaaatata aaggtttatc cactacttga ttcagttggg
    37441 atcgcctcct ttttttcatt ataagtgaag gattgaaaaa aacaaatcag tttgattgtt
    37501 cgaattttca attttttatg ttctatttgt taattccttc attttgtaag ataatgggca
    37561 cacgaaacaa aaaaggagcg atcgatgaat gaacaaagaa cgattgaaac aagatttcta
    37621 tgaagcagtc aatgaagaat ggcaaaaaac agcaaaaatc cctgcagata aaccagctac
    37681 aggcggtttc caagatttag ttgacgggat cgaccaactt ttgatgggag aaacagacga
    37741 tctgcttgcc catccagaaa aagtgtcttc agaaaaaatg aaacatttcc ttgcatatta
    37801 tcaactggca aacgattatg accgaagaaa tgagttgcat gctcaaccgc ttcaacctat
    37861 aatcgaaaaa gttgaatcat tgcagtcttt cgacgaattg aataagcaat ttccagaatg
    37921 gctgttggat acattaccat tgccatttaa tctggatgta gatgcagata tgaagaatgc
    37981 gcaaacgaac gccttctttg cttatccgcc ttctttattc cttccagata agacgtatta
    38041 tgcatcagac catcccaacg gtgcacaact aataggcgtt ttctttgata tggctgttca
    38101 gttattagag cttgccggca aagaaaaaag tcaggcagaa gcaatcacgg aacaagcagt
    38161 gcaatttgat aaattgattg ctcctcatgt aaaaagtgca gaagaaaacg cagattacag
    38221 caaaatgtat aatccgcaat cttttgatac atttattaaa tacacagata aactggactt
    38281 gaaaaaactt gtcacgggtt tgattgggac aactccagat aaagtgatcg taactgatcc
    38341 agtgtacttc gatcatttga atgacatcct gacagaagct cattttccgt tattcaaaag
    38401 ctggatgatc attaaaacag tacgttctct tagtggttat ctatcagaag aattccgcca
    38461 agtcagcgga atctattctc gcgtattgtc tggaacagac gaagcaatgc ctcagaaaaa
    38521 agcagcgtat taccttgcct ctggacaatt cgatcaagta gttggcgatt actacggaaa
    38581 aaaatatttt ggcgaagctg ctaaaaaaga cgtagaacaa atggtgaaaa aaatgatcgc
    38641 cgtttataaa aaacgtctag aagaaaatga ctggcttggg gatgcaacaa aagaaaaagc
    38701 cgtcataaaa ttaaataact taggtatcca agtaggctac cccgataaga tcccagcatt
    38761 attcgaccag ttcaaaacag tacctgcaga tcagggtggt actttgcttt caaatactct
    38821 tgttttcagc aaactcacat taaaagatcg tttcagcaaa tggaacaaac cagtggatcg
    38881 ttcagaatgg gaaatgagtg ctgacacggt caatgcttat tatcatccat ttcggaatgt
    38941 gatcgtcttt ccggcagcga tccttcaagc accattttac agtctagaac aatcaagctc
    39001 tgctaattat ggtggaatcg gagctgttat cgctcatgag atttcccatg catttgataa
    39061 taacggcgct ttatttgacg aatatggcaa cttgaacaac tggtggacag aagaagatct
    39121 tacacaattt caaaacaaag cacaagcaat gatcgaagaa ttcgatggtc tgccttttgc
    39181 tgacggaaaa gtaaacggaa aattaaccgt ttcggaaaat attgctgatg caggcggtct
    39241 aagctgtgca ttggaagcag caaaaacgga atcagatctt tctatcgagg aattctttgt
    39301 caattgggca acgatttggc gtacaaaagc aaaaaaagaa taccaacaac ttttactgca
    39361 aatcgatgtc catgcccctg ctaaactccg agcaaacgtg caaccaaaaa accttgacga
    39421 attctatgaa acatttggta tcacggaaca agacgctatg tatctagcgc cagaaaaaag
    39481 agtgcgaatc tggtaagagg ttgtgccaga agtggtcagc ttcaagaaat aagaaggaat
    39541 ttgggaaaat cgcttctcaa atttttgtga catttcggct tatttttcga agaagttact
    39601 tctggaatac catgtattag aggttgtgaa aaagctgctt agtttcaagt agtaagaaaa
    39661 attttgtgaa aatggctttc cacatttttg cataaatttg acttactacc gagaaactgg
    39721 cttttgaaca ccgtttatcg agaggttgtg aaatcagcgt cctgacctga gtattagaga
    39781 aaaaaacgga aaaatagttc ctcatatttt gccgtttgtt gagctaatac cgagggtcag
    39841 ctgattgaac accgtttagt ggagagattg tgaaaaagct gtcctgcatc aagtaataag
    39901 aacagccaat caaaagcagc aaggagaacc tcatctataa aaagatagaa ggaagtgaga
    39961 catctattgg tctcatttcc ttctattttt actttcctca gtcaattgtt ttacatcata
    40021 aaaggagaaa ttccacttat ttttttcgct gtttcatgac ataaacaact acaccgatta
    40081 acaaaattcc tccagctaat gctagcaacg ggttattaaa ttctcccgtt tttgggagtc
    40141 cttgagtgcc atttttttca ctttcttttg ctgtcctatc cggatgagaa ggttttccat
    40201 ttggttttcc atttggtgat tcatttcctg gattttctct ttctggtttg tcatttcccg
    40261 ggggcacatc ggcagtttct cgcacagtga tcgctttttg ctgggtaaca gattctgtat
    40321 gagcagacca tttttcccca tcaaatattt ccgaacgata agtgacttct agcgtatatt
    40381 ctccttttga aggtgctgaa aaaatagcgg tatgattaga aaattgagca cttgactgtg
    40441 tttcaacgat ttggatcttt tctgggaaat aacgcatatc ttcaaagaca ggcgttcctt
    40501 gatttggtgt gaaagttgac acaaaaactg taaaaggctt cagttcaatg atatttcctt
    40561 ctgcattctc cgccacacca tttgcttctt gtataataat cggattattt tgttcatttg
    40621 gttttgtctg atttggttct tgtacgattg catactctgg atattccgaa gacggtgagg
    40681 tttctccgtc aaaaatagca cctacagata atggaagacc atccactctt tccttttctg
    40741 tttgacgatt ccccggttta atctgcatca gtccatgaac atggatactt ccattttcat
    40801 agcgcgtaac aggctgctga ccttctttcg aacatgtatt tagagactcg atccaatctt
    40861 ttgatatggt atgtccaaga gtattttctg attgtttctc tcgttcattc caatagtagt
    40921 tcaacgagtg gtagatttga tcttcgtttt gattcaatgg gcggatctgc tctctcatct
    40981 caagattctc tgttcggaaa gataagatac cagaagcatg gtagtctgtg tttcctgctg
    41041 aagaggtata aagagccaca ttatatgaac cgttattaaa acttgtactg ctattgacga
    41101 taatatctgt tccgctattg gaatcgattc ctttcgcaag attttcgaaa gacaaactat
    41161 tgatcaattc atgagggccc gttaaagaag aaccgcccat tttgaatcca ttaccgttac
    41221 cttctccctc aattcctggt acccagccgt ttcgataagc aactgagttt ttgatgatta
    41281 cttttccgat cgaacctgtt tcatttttag caaaaaggtc ccaaccgtca tctgcattat
    41341 gatacgcgat acaaccgtca aatacatttc cttctcctat tgtcagtttg gccgcaaatc
    41401 catcggcatc ttcaaatcct ggatcggcat tttcaaaaga tgtacagttc ttgactaagt
    41461 tatgcgcggg ccatgcttcg aaaggatcat ttgagctacc gctgatttgg attcctgtat
    41521 ttccattccg ataagcatga atctcttcga tcaaattatg atttccagaa atctgtaatc
    41581 ctttttgcat agctgcacta tttgtaatgt caaaccctcg taaaccccag tagtgactga
    41641 acagtgtcat cccatttcca gttcctttaa aatcaagtac aggacgcttg ttttctggat
    41701 ttttctctgc aatcaactga atcgggtttt ctcttgtccc gttaacgcct tttggaatcg
    41761 tcaatcctct ttcgaaggaa taagttccag gcgccatgac gattgtctgc ccagcatatg
    41821 cgtatctcaa tgcttgtgtc agagataatg gattttgtct gcttccgttt cctgcatctg
    41881 acccttctgg tgttacataa actgtcgaat atttaggttt acggtagtcc actgtatgaa
    41941 gaatctcttt tgtttcataa ctagtcatct ctacgtattc ttctggcgga tagtttttat
    42001 ctggcgtaaa actgaaagta aattcgttcg ttccttccat cagttttgtc tgataatcaa
    42061 attcccgatt cgcagtgata gccaagtttt ttgcgttctt aagcacctct cctgttgctt
    42121 tatttttaat tgtcaataat ccgtcagcat ttgctctaaa ggacatagta tgatcttggt
    42181 ttcctgaatg attactagag gtcacagtgt aaatcggatc aatcaagcga gtaggtcttt
    42241 cttgcccagg aggatctgtc gcaggatctg agtaagcaac ttcgattcct tctaccttga
    42301 tcgtcatatt ccttgctgca gcaaatcctg cataaataac cgattcatct gaagcgtata
    42361 atttttccca gtcatacatg atgtcagaag ccatttcttc tcctgtttca ggatcgtaat
    42421 aatatgcctc taaaccagta ttcgtttttt tcatctctac gtccagttta gtaatcgagt
    42481 tcgtggccgg aaacagattc ccatgaccgt ttccgaatat attataagaa cctgtttctt
    42541 tttccaagaa ccctgctgaa gtctctaaag gtgttgtttc cactgagaca ctcccaggag
    42601 ctggcgcagc ttgcggatct tcagatgata ttcctgtgat tgcccgtgtc cccaatccaa
    42661 gtcgcatcgt atatttgctg ccgctcgtgt tgaccacttc ttgtctatcc gagtcccaga
    42721 catattcgat ccgactgcct agtatggcaa atgaatttga ataaaatgcc tgcccaaaca
    42781 aatgattttt tggtactgcg tctcttacca ttaaagcaaa tccttcttgg gcattcgtat
    42841 aggtccaaga ttctatttcg atcgtcgccc gcatcctaaa gttgatgtct ttggggattg
    42901 cttgataata ataggtcatt ccatctgatc cgcttgactg gaattttccg ccgttattcg
    42961 tggaagagag ccgcacgccg tcttctaatg gttcaatggc atacctacta gcacttgtgc
    43021 tttctccgaa aacaacccct ttccactctt catttgcttc ttcagattgc ttttttgtct
    43081 tttcattttc tgattctttc atcataggat catttccttc ttccgtatcc atatcttcac
    43141 tagttcttgg tatttcctcc attgttgaca tcccttcaat gttcacgtgt gcattttctt
    43201 cgttcacaga ctgttgttcg ttagcagcaa cttcaacgac agaaattaaa accggggtac
    43261 tgagcataag gagattcatc attagcgcac tgtattttat acgttttttt aacaagtgta
    43321 ttcctcccgt aacaaattag aaagcgttta cttaaagtat tacctaattt atttttactg
    43381 tcaataaaaa acaaaattat aataagtgta ttttataaaa agaaaaaata taacttaagt
    43441 tgttgataat aaagagattt attaacgg
//
LOCUS       DAIGUC010000020        42516 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.020, whole genome shotgun sequence.
ACCESSION   DAIGUC010000020 DAIGUC010000000
VERSION     DAIGUC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.020"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..595)
                     /locus_tag="NOB46_001139"
     CDS             complement(<1..595)
                     /locus_tag="NOB46_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1058091.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDE"
     gene            788..1819
                     /gene="queA"
                     /locus_tag="NOB46_001140"
     CDS             788..1819
                     /gene="queA"
                     /locus_tag="NOB46_001140"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCI1058092.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            2438..5077
                     /locus_tag="NOB46_001141"
     CDS             2438..5077
                     /locus_tag="NOB46_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1058093.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(5245..5943)
                     /locus_tag="NOB46_001142"
     CDS             complement(5245..5943)
                     /locus_tag="NOB46_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI1058094.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            6161..7306
                     /gene="tgt"
                     /locus_tag="NOB46_001143"
     CDS             6161..7306
                     /gene="tgt"
                     /locus_tag="NOB46_001143"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCI1058095.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            7403..7783
                     /gene="yajC"
                     /locus_tag="NOB46_001144"
     CDS             7403..7783
                     /gene="yajC"
                     /locus_tag="NOB46_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCI1058096.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            8088..10685
                     /gene="adhE"
                     /locus_tag="NOB46_001145"
                     /gene_synonym="adhC"
     CDS             8088..10685
                     /gene="adhE"
                     /locus_tag="NOB46_001145"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCI1058097.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            10914..12020
                     /locus_tag="NOB46_001146"
     CDS             10914..12020
                     /locus_tag="NOB46_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI1058098.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            12037..13061
                     /locus_tag="NOB46_001147"
                     /pseudo
     CDS             12037..13061
                     /locus_tag="NOB46_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            13067..13546
                     /locus_tag="NOB46_001148"
     CDS             13067..13546
                     /locus_tag="NOB46_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCI1058099.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            13562..14341
                     /locus_tag="NOB46_001149"
     CDS             13562..14341
                     /locus_tag="NOB46_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HCI1058100.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYKWVIRF"
     gene            14305..14628
                     /gene="kduI"
                     /locus_tag="NOB46_001150"
                     /pseudo
     CDS             14305..14628
                     /gene="kduI"
                     /locus_tag="NOB46_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            14648..15451
                     /locus_tag="NOB46_001151"
     CDS             14648..15451
                     /locus_tag="NOB46_001151"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HCI1058101.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(15700..16764)
                     /locus_tag="NOB46_001152"
     CDS             complement(15700..16764)
                     /locus_tag="NOB46_001152"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCI1058102.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(16761..17846)
                     /locus_tag="NOB46_001153"
     CDS             complement(16761..17846)
                     /locus_tag="NOB46_001153"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HCI1058103.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(17859..18836)
                     /gene="mvaD"
                     /locus_tag="NOB46_001154"
     CDS             complement(17859..18836)
                     /gene="mvaD"
                     /locus_tag="NOB46_001154"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HCI1058104.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(18829..19773)
                     /gene="mvk"
                     /locus_tag="NOB46_001155"
     CDS             complement(18829..19773)
                     /gene="mvk"
                     /locus_tag="NOB46_001155"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HCI1058105.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            20088..20747
                     /locus_tag="NOB46_001156"
     CDS             20088..20747
                     /locus_tag="NOB46_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI1058106.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            20832..21737
                     /locus_tag="NOB46_001157"
     CDS             20832..21737
                     /locus_tag="NOB46_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI1058107.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(21739..22371)
                     /locus_tag="NOB46_001158"
     CDS             complement(21739..22371)
                     /locus_tag="NOB46_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI1058108.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    22522..22647
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            22691..23215
                     /gene="infC"
                     /locus_tag="NOB46_001159"
     CDS             22691..23215
                     /gene="infC"
                     /locus_tag="NOB46_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCI1058109.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            23287..23487
                     /gene="rpmI"
                     /locus_tag="NOB46_001160"
     CDS             23287..23487
                     /gene="rpmI"
                     /locus_tag="NOB46_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCI1058110.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            23540..23899
                     /gene="rplT"
                     /locus_tag="NOB46_001161"
     CDS             23540..23899
                     /gene="rplT"
                     /locus_tag="NOB46_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCI1058111.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            24251..25489
                     /locus_tag="NOB46_001162"
     CDS             24251..25489
                     /locus_tag="NOB46_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCI1058112.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLGISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAES
                     YTYNDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLL
                     PVLGVVLLDLPIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGF
                     LMTLAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFHGPMNLVGSGSA
                     ILAVVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIP
                     TGWIIGAILCLITFLLYGNA"
     gene            25537..27666
                     /locus_tag="NOB46_001163"
     CDS             25537..27666
                     /locus_tag="NOB46_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCI1058113.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            27641..28330
                     /locus_tag="NOB46_001164"
     CDS             27641..28330
                     /locus_tag="NOB46_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058114.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFVTYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(28738..29424)
                     /locus_tag="NOB46_001165"
     CDS             complement(28738..29424)
                     /locus_tag="NOB46_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1058115.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(29560..29754)
                     /locus_tag="NOB46_001166"
     CDS             complement(29560..29754)
                     /locus_tag="NOB46_001166"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058116.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(29804..30244)
                     /locus_tag="NOB46_001167"
     CDS             complement(29804..30244)
                     /locus_tag="NOB46_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HCI1058117.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(30248..31093)
                     /locus_tag="NOB46_001168"
     CDS             complement(30248..31093)
                     /locus_tag="NOB46_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HCI1058118.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLEKQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            31242..32660
                     /gene="pepV"
                     /locus_tag="NOB46_001169"
     CDS             31242..32660
                     /gene="pepV"
                     /locus_tag="NOB46_001169"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCI1058119.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(32736..33938)
                     /locus_tag="NOB46_001170"
     CDS             complement(32736..33938)
                     /locus_tag="NOB46_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058120.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
     gene            complement(33925..35712)
                     /locus_tag="NOB46_001171"
     CDS             complement(33925..35712)
                     /locus_tag="NOB46_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058121.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            complement(35725..36678)
                     /locus_tag="NOB46_001172"
     CDS             complement(35725..36678)
                     /locus_tag="NOB46_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1058122.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            complement(36863..37213)
                     /locus_tag="NOB46_001173"
     CDS             complement(36863..37213)
                     /locus_tag="NOB46_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI1058123.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            37413..38492
                     /gene="pepA"
                     /locus_tag="NOB46_001174"
     CDS             37413..38492
                     /gene="pepA"
                     /locus_tag="NOB46_001174"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HCI1058124.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            38635..38955
                     /locus_tag="NOB46_001175"
     CDS             38635..38955
                     /locus_tag="NOB46_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI1058125.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTASWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            38977..39441
                     /locus_tag="NOB46_001176"
     CDS             38977..39441
                     /locus_tag="NOB46_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1058126.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            39648..40253
                     /locus_tag="NOB46_001177"
     CDS             39648..40253
                     /locus_tag="NOB46_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HCI1058127.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(40292..41581)
                     /locus_tag="NOB46_001178"
     CDS             complement(40292..41581)
                     /locus_tag="NOB46_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCI1058128.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            42010..42489
                     /gene="rlmH"
                     /locus_tag="NOB46_001179"
     CDS             42010..42489
                     /gene="rlmH"
                     /locus_tag="NOB46_001179"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCI1058129.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT        13468 a         7880 c         8879 g        12289 t
ORIGIN      
        1 cttcatccat gtcatgggtt acaaatacga tcgtttttcc caaacgctct tgtaaatctt
       61 tgacaaggtc ttgcaaggaa tcacgagtga ttggatcaag cgcaccgaat ggctcgtcca
      121 tcaagatgat atcttgattc gctgcaaggg cacgaacgac tccaatacgc tgctgctgac
      181 caccagataa ttcatgtggg tagcgatcta acatctcacg gggcaattcc acaagatcaa
      241 tcattttttc agctgtttta ttccgttctt cttgactgac tttcaacaat ttttggacaa
      301 gagtgatatt ttcacggatc gtcatgtgag gcatcaatcc aatactttgg ataacatagc
      361 cgatctgacg tcgcaattcc actggatcaa tttcttggat ggattttcca tcaatcaaaa
      421 ttttcccttg tgttggatca gtcattcggt tgatcatccg catcgtcgtc gtttttccgc
      481 ttccgctcgt accgataaaa caaatgaact cacccttttc aaatgaaaga ttgacgtcct
      541 ctacagcgac ttttccacct ttataaattt ttgacacatt ttgaaattca atcatggtgc
      601 cacctctttt tctattttca atgaagaact atctattact agtatgccta aaacaatgaa
      661 aaaatacaaa tagggtagtt tttttattta ggaaaacaaa aaatagaagt gaaaaagtgc
      721 tgattttgcc aacagaacga aaaacatgat agaatgatga agcacatgat agaaagtgag
      781 tgacgatatg ttaacaacag aagattttga ttttgacttg ccggaagaat taatcgcaca
      841 aacaccatta aaagaccgcg atcattctcg tttacttgtt ttggatcgga aaactggaga
      901 gatggaagat aaacatttcc atgaaatcat tgaagagtta cagcctggtg atgcgctagt
      961 tatgaataat acacgagttc tgcctgctcg tttatatgga gaaaaaccag atactggtgc
     1021 gcatttagaa gtccttcttc taacgaatac acaaggagat acgtgggaga cattgatcaa
     1081 acctgcgaaa cgtgccaaag ttgggacaag aatctctttt ggtgatggca gattgcaagc
     1141 agtagtgaaa gaagaattgg aacacggcgg acggatcatt gactttgagt atgaaggaat
     1201 ttttctagag attcttgaat cattgggaga aatgccattg cctccatata tcaaagaacg
     1261 tctggaagac ccagatcgct atcaaactgt ctatgcgaaa gaaaatggtt ctgctgcagc
     1321 gccaacagct ggattgcatt ttacgaaaga attacttgat gagatcgaag caaagggtgt
     1381 tgaattagtc tatctgacac tacatgtagg gttaggtaca ttccgacctg tcagcgtaga
     1441 taaaattgaa gaacaccata tgcatagtga attctaccgt ttgacggaag aagcggctga
     1501 gcgattgaac caagtacgta aaaatggcgg gaaaatcgtg gctgtcggaa caacttcaat
     1561 tcgaacatta gaaacgattg gaacgaaatt taatggagaa atcaaagcag acagcggatg
     1621 gactgatatt ttcattacgc ctggctatga attcaaagtg gtagaagctt tctcaactaa
     1681 tttccatttg ccaaaatcga ctttagtcat gttagttagt gcctttgcag gaagagaatt
     1741 gactttatct gcttaccagc atgcgattga agagcgctat cgtttcttta gttttggaga
     1801 tgcgatgttc gtgaaataag gttatgaaaa gccgctagtt ttgaataaca aaaaagcttt
     1861 acaaagattt tatgacaaag aaaaagccga gctctcgata agctcggctt tcttgtacct
     1921 cggaaggatt caaataaaca gaaatgattg taactttcca tcatacatgc aaagcacggt
     1981 gttgaatttc ttcatgttaa acaaaaattt tgttttcgtt acatcttcaa catttgaaac
     2041 atctcttgtt cctattcaat tttcagacgt ttacgttatt caattgttac gtatcgcatt
     2101 acttcttgtt tcggatactt cgtgatccaa acatccatac gcattcacta tttataggtt
     2161 tgtactctac acgcatgtct gggtgaaacc tgtacttcta acaactttgt ttgcttacac
     2221 tgttctatcg agaaattctt ctgtctattt gatggtatcc tccttcctta catctatata
     2281 atagcatcct ttggtagcgt ttgcaaatat aagcacttta aattttacgc tttcttaaca
     2341 aataatcgat aagcccttta tttgaagtaa ataaaaaaag gatgttatag taaaataagt
     2401 accttttttt gtacgaagat tttaaaggag gaataggatg gaagaataca agcagacaat
     2461 agaagaagta aagaaggtaa cagaagcaga tccagatact gggttgtctt cacaagaagt
     2521 ggatgaacgg cgaaaaaagc agggattgaa taaattcgat gaggcgccga aagaatcgat
     2581 gatcaaaaaa ttctttcgaa gcttgtccga ttttacaacg atcatccttc ttgtagcagc
     2641 ggtgatttcc ttttataccg catttgctac agaacatggg gatttatttg aaggactgct
     2701 gatcatcgct atcgttgtga tcaactcggt attggcgatt gtccaagaag gaaacgcaga
     2761 aaaagcactg gaatccttgc aagatatgaa taaacaaacg gcaactgtca tacgagacgg
     2821 caaagtgacc actgttgagt cagagcaact ggtagtgggt gatattcttg ttttagagtc
     2881 cggtgatgct atttctgccg atgcccgttt gatcgaagca tcacaattac gtgtagaaga
     2941 atcggcgttg actggagaaa gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga
     3001 agatgagtca ttaggtgacc aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg
     3061 tcgtgggaaa gcgatcgtca ctgccattgg catggctaca gaaatgggta agatcgcgga
     3121 tcttttgaac gaaaatacta tgcaaaaaac acctttacag gtccgattga atcagctagg
     3181 caaacgaatc agtatgatcg ctttagcggc tgcggcttta gtatttgtga ttggtgaact
     3241 gcaaggagaa ccactccttg agatgttcat gacttcgatt tccttggctg ttgcagctgt
     3301 accggaaacc ttgactgtta ttgttacgtt gacacttgca tacggtgtgc agaagatggc
     3361 gaggaaacat gcgatcatcc gacagttgcc agcagttgaa acgctaggaa ccgctaatgt
     3421 tatctgctca gacaaaacag gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg
     3481 gagcaaagaa gatgaagtaa cgaatatcga agattcaatg acgaacagcg cgatggaaat
     3541 attgaaaatg gctgcactat gtacagatgt gacggtcgag caagaagatg acgaccttgt
     3601 tatcaaaggt aatccaacag aagtagccat cgtaagggct gttgaagaga attatcatac
     3661 aaaggcagaa ttagaagaaa aatatccacg agtaaacgag cttccttttg attctgaacg
     3721 aaaaatgatg acaacagttc accaaatggg cgaaaaatac atctcaatca ccaaaggagc
     3781 attcgatgtt cttgctccgc gctttagttc aggcgatgta gaacaagcgg cgatcgttaa
     3841 tgatcgcttt ggtaaacggg cactgagagt gattgctgtt ggttatgcta cttatgacga
     3901 agaaccgcaa gatatttctt ctgaagcact ggaaaaagac ttacgtttga ttggtctgat
     3961 cggaatgatc gatccaccac gtccagaaag taaaggagca atcaagcgag cgaaaaaggc
     4021 tggcatcaaa acagtcatga tcactggaga tcatgtggtg actgccagtg ccatagcgaa
     4081 agaattaggt atcttgaatg atccgtcaga agcactttca ggatcagaac tgcatcaatt
     4141 atcagacgaa gaattagatg cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc
     4201 agaagacaag atccggatcg tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac
     4261 tggggatggt gtgaatgatg caccagcgtt gaaagcaagt aacgttgggt gtgccatggg
     4321 gatcacagga acagatgtgg cgcaaagtgc cgcagatatg attttgacgg atgacaactt
     4381 tgcgacgatc gtagacgctg tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc
     4441 tatcaacttt ttgctaagct gtaatatttc ggagatcttt attgttttga ttgcgatgct
     4501 gttaggatgg ggagcaccat ttacagctgt gcaactactg tttgtcaatg tagttgctga
     4561 tggacttcca ggatttgctt taggaagaga gccagcggaa cacggcatca tggatcagcc
     4621 acccattccg aaaaatgaag ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa
     4681 tgcaggggtc ttcaccatcg taaccttgtt tggttattat ttaggtagtt atgtcgatac
     4741 tatcagccca tgggtagacg caagtcagca tgtcggtcaa actgttgcat tcttgatctt
     4801 agcttattca tcgattctgc atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt
     4861 caatttagcg accaataaag ctttggtaga aatggcgtta ctggcattag ctattacaac
     4921 ggctgttgct ttgctgccat ttacgcaaga actattcggc ctagtacaca tcagtttgaa
     4981 tcactggttc ttggtaggga ttttatctat cgtaccaatc gcggtgaatg aactgatcaa
     5041 gttccatcga ttaccggaag cagaagaaga ggaatgatta actgtttcta agttgatttt
     5101 ctttttactg gaactataca aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt
     5161 gctaatgggc tgaatgtttc ttttactgcc tctcgataaa cggtgttctc ctgccacccc
     5221 ctcggtcaca agtcacactc tcttttaaat atcttttggc aattgttcat aaaatgctgc
     5281 ttttgttgca gaaatgtatg ggctgagcca tagataacca ataccagcag ttgctaatgc
     5341 taagatatgc cagccgataa atgaaagatc taaccagaaa agttgtcctt tataaccatc
     5401 catcaatttt cgacttgcag tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg
     5461 gacgatatcg tagtaaataa aatagctttg agaataagaa tagcttttaa tgattccagg
     5521 aataactaat agcaaacccc ataatgttgt aaagatcgag atcagcacag ctaagctgat
     5581 cactccgccg ataaacaaac ctttgaatcc acgaaatgca tctttgaatg gttcgatctg
     5641 atctttttgt ccacgtaaaa tatcaagata agtccaagaa ataccgctca tgaacaaagc
     5701 gctaatgatg ctggaaataa ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt
     5761 cgcttctgag acgctcgctg atccatcata tatggtggtg gcaaacaaga taataggaat
     5821 cataataaga agaatagtag caataccaat caatgtaggg attagattta gtaaaacagc
     5881 ttgtccccaa cgtcctttta gactctcttt tgcttggcgt tttaattctg cagaagattg
     5941 catgattttt ccctcctttt ctttaataac accaatatac catgtatcaa aaaatatttc
     6001 tgtcataatg tttttctttt ttttgttatt cataaaaaaa ggataaaaaa aagaatatta
     6061 aataaagtag aaggaagccg agggaacttg caaaaagcac ttgaaacgat tatgatggtg
     6121 ggagttgtca agatatttta tatagaaagt agggaaatga atgacgcaac ctgccattcg
     6181 ctatcgttta atcaagaaag aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc
     6241 acacggaact ttccccacac caatgttcat gccagtagga acattagcta cagtaaaaac
     6301 aatgtcccca gaagagttga aagaaatggg tgctggcgtt attttaagta atacatatca
     6361 tttatggcta cgccctggtg aagacttagt agaagaagct ggcggactgc ataaatttat
     6421 gaactgggat caaccgattt taacagattc aggcggcttt caagtttttt cattaagtga
     6481 tatgcggaat atcgaagaag aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat
     6541 gtttttatca ccagaaaaag caatcaacat ccaaaataaa ttgggctctg atatcatgat
     6601 gagttttgac gaatgtccac cattcgatga aagttacgac tacgtgaaaa aatcagtaga
     6661 acgtacgtct cgatgggcag aacgaggatt gaaagctcat gctaatccag accgtcaagg
     6721 attatttgga atcatccaag gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga
     6781 tctagtcggg atggatttcc ctggttactc aatcggcggg ttatctgtcg gggaacctaa
     6841 atcagaaatg aatcgtgtat tagaattcac tacaccgttg atccccgaaa acaaaccacg
     6901 ttacttgatg ggtgtcggtg ctgctgattc attgatcgat ggtgttatcc gtggagtaga
     6961 catgtttgac tgtgtcttgc ctactcgaat cgctcgaaat ggcacatgta tgacttctca
     7021 aggccgtcta gtagtgaaaa atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa
     7081 atgtgattgt tatacatgta aaaactatac acgtgcctat atccgccatt tgatcaaatg
     7141 tgatgaaaca tttgggattc gtttgacttc ttaccacaat ttatacttct tgttgaatct
     7201 aatgaaacaa gtacgtcaag caatcatgga tgataatttg cttgaattta gagaagcctt
     7261 ttttgaagaa tacgggttca ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta
     7321 aaaattaagt aaaaaactag tgttatcagc atttttctgc taaagtgttt tttgtagata
     7381 cagaattagt gaggtgaaaa aaatgggaac attaccaatg cttgtgatgt ttatcgcgct
     7441 attagcaatg tggtttttta tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa
     7501 cttgttagat agcatgaaac caggtgattc agtcgtaacg atcggcggat tacatggagt
     7561 tgtttcagaa atcgacaatg acaaacggac agttgtttta gactgcgaag ggatcttcct
     7621 tgagtacgat cgtgcagcaa tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc
     7681 aacgactact gttgaaacaa cagaagaacc agctgagaca gttgaagtaa aaactgaaac
     7741 aacagaaacg ctggaagaga cagaagagaa ggaagaaaaa taagtatcaa agcttattta
     7801 aagacgaggt agggcagaaa gatgtcctac ctcatttttt attcaaaaaa gaaagagata
     7861 agagcatggg atatattgct caatattgaa taatcgggtg tgtcatataa ataataataa
     7921 ataactttat atatttttct atacaaacac ctgtaaataa agcaatttta tatttaaaaa
     7981 taactgtgaa aaaaatcaca aaaaagtgtt tacatagaaa aataaatatt gtatgatata
     8041 catgtgaatt atttaacaaa taaccatgac ccattaggag gataatgatg gctaaagtaa
     8101 tagaaaaaga aaaaacgaag acaattgacg tacaagcaat gattgatgat ttggcagaaa
     8161 aagcaaatgc agcattgaaa gaaatggaaa gctttgatca agaaaaagta gaccatatcg
     8221 tgcatgaaat ggcaatggca gctttggatc aacatatgcc attagcgaag atggctgtag
     8281 aggaaacagg ccgcggtgtt tacgaagata aagcaatcaa aaatatgtat gcgtccgaat
     8341 atatttggca taatatcaaa catgataaaa cagttggtgt gatcaatgaa gatgtccaaa
     8401 aagggttgat tgaaattgct gaaccagtcg gtgtggtttg cggagtaact ccaacaacga
     8461 atccgacttc cacaacgatt ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg
     8521 tttttgcttt ccatccaagt gcccaaaaat cttctgcaga agcagcacga gtggtacgtg
     8581 atgctgctat cgctgccgga gctcctgaaa attgtatcca atggatcgaa catccttcga
     8641 tcgaagcgac ttctatgcta atgaaccatc caggtatcgc gatcgtctta gcgacaggtg
     8701 gagctggaat ggtcaagtct gcttactcta caggaaaacc agctttaggt gtaggtccag
     8761 gtaacgtacc agcttatatt gaaaaaacag caaaaattaa acgtgcagtg aacgatttga
     8821 tcgtttcgaa aacatttgat aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg
     8881 ataaagaaat ctatgcagca gtaaaagcag aattccaagc acaccaagtt tatatcgtaa
     8941 aaccagatga attgcaaaaa ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca
     9001 atccatcaat cgttggacat tctgcgatgg aaatcgcaaa attggcagga atcagtgtac
     9061 caaaaggaac gaaaatgctg attgctgaat tggaaggcgt aggcccagat tatccgctat
     9121 caagagaaaa actttctcca gttcttgcca tgatcaaagc taacaacacg gaccatgcgt
     9181 ttgatttgtg tgaaggtatg ttgaatcttg gaggattagg acatacagca gttatccatt
     9241 cagaaaacga agagttgcat gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag
     9301 tgaatacacc atctgcagaa ggcggcatcg gtgatatcta taacgaaatg attccgtcat
     9361 tgactttggg atgcggttct tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa
     9421 acttaatcaa tgtcaaaact gtagcgaaac ggagaaataa catgcaatgg ttcaaattac
     9481 cgccaaaaat cttctttgaa aagaactctc tattgtactt agagaaaatg gaaaacgttg
     9541 aacgtgtcat gatcgtttgt gaccctggta tggtccaatt cggttactgc gatacagttc
     9601 gtgaagtatt ggcacgacgt aaaaatgatg tgaagatcga agtcttctca gatgttgaac
     9661 cgaacccatc gacaaatacc gtatacgcag gaacgaaact gatggcagac ttcaagccag
     9721 atacagtaat cgctcttgga ggcggttctg caatggacgc agctaaggga atgtggatgt
     9781 tctatgaaca cccagacaca tctttctttg gtgcaaaaca aaaattcttg gatatccgta
     9841 aacggacata taagatcgac aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat
     9901 cagggactgg ttctgaagta acgccatttg cggtcatcac tgacagtgaa acacatgtga
     9961 aatatccgtt agcagattat gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg
    10021 tcatgtcagt tccagcatct gtcacagcag ataccgggat ggatgtgtta acacatgcaa
    10081 tcgaatccta tgtttcagtc atggcttcag attatacacg tggattgagc ctacaagcaa
    10141 tcaagttagt ctttgactat ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg
    10201 aaaaaatgca caacgcttct acaatggctg gtatggcgtt tgctaacgca ttcctaggta
    10261 tttgtcactc agtcgcacat aaaatcggcg gggaatacgg gatccctcat ggacggacaa
    10321 atgcgattct tttaccgcat attatccgct ataatgcaaa agatccacaa aaacatgcga
    10381 tgttccctaa atatgactat ttccgtgcag atacagatta cgcagatatc gcaaaattct
    10441 taggtctgaa aggcgaaaca acagaggaat tagtcgaagc tttagcaacg gctgtttatg
    10501 aattaggaaa atctgtcggc atcaacatga gtctaaaagc tcaaggagtc acacaagaaa
    10561 cactagatac aaccgtagac cgtatggctg aattagctta cgaagaccaa tgtacgacag
    10621 ctaatccgaa agaaccattg atctctgaat tgaaacagat catcattgat gcttacaacg
    10681 gataagcaaa agaaagcgta gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa
    10741 cgttgtttct ccaagttctt tttttaattt ccaagtaact gaaagttact tttgttattt
    10801 aacatttagg tcaattttag acagtttttg ttcaaaaagc gatatttata gtggacggta
    10861 ttactgctat attaaggata taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta
    10921 ttaaagaaga gatttttgta cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg
    10981 aaaacctgac aacgatcaaa gacgataatg gtgaattttt gttggacttt gatggactga
    11041 aagtagatga caaaagctgg acagtgtgga attggccaca aggtgtcggt ctatatggta
    11101 tttataaaaa ttaccagatg acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt
    11161 ttgaggatcg tatggaagaa ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat
    11221 tgactatggc ttacttgtat gaagacacga aagattcacg ctatttgcct tatttagaac
    11281 aatgggcaga atgggtcatg aatgacatgc ctcggacaaa tgaagacggg ttacagcatg
    11341 ccacatatgg accggaaaat aagaatcagt tgtgggacga tacattgatg atgacagtgc
    11401 ttcctttggc aaaaatcggg aaactgttga atcgcccaga atatttagaa gaagctcgtt
    11461 accagtttat gatccatatc aaatacttga tggataaacg aacaggattg tggtatcacg
    11521 gctggacgtt tgaaggaaat cataactatg ccgaagcatt ttgggctcgt ggaaactgct
    11581 ggttgacgat tgctattcca gagatcattg aaatcttaga attatcgaaa gaagatgcat
    11641 tgcgcaaatt attgatcgaa acacttgaag cacaagtgcg tgcattaaaa acttatcagt
    11701 ctgaaagcgg tttatggcat acgttgttgg atgatccttc ttcttacgta gaatcttctg
    11761 caactgcagg atttgcttac ggtattttga aagcggtcca taaacgttat ttaccacaag
    11821 aatataaaga agtcgcttat cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag
    11881 gagaagttca aaacgtttca atcgggacag gaatggggga cagtttagat ttttatcgga
    11941 atatcggaat cacagcaatg ccttatggac agtcgttaac ggtgctttgt ttgacagaat
    12001 tgctcgtctc ttattgttaa aagaaaggaa acccatatga aaaaaacatc actgctgttt
    12061 gcagcaagtt cgcttagcct aggtctgcta ggtctaagcg gctgcggaaa taattctagt
    12121 gtggcaactg tcgcagatgc agacgtaaat gagatagtta ccttgcgctt tgcttatgca
    12181 agcaacagcc agtaattgat gcaatgaatg aatttgggcg tttagtaaaa gaaaaaacag
    12241 atggttccgt acagatccag tatttcccag atggacaact gggtggagac cgtgaactga
    12301 tcgaattgac acagtcagga gcagtagatt tcacaaaagt aagtgcctca gcgttggaaa
    12361 gtttctctaa agattattcg attttttccg ttccttatct attcaatgat gaagaacatt
    12421 tctttaaggt gatggataat gaagaaataa tggagccaat ctaccaatcg accaaaaatt
    12481 taggatttac cggattgacc tattatgatt ctggtcagcg cagcttttat atggtagacg
    12541 gtccgatcca tacgccggaa gatttgaagg gaaagaagat ccgtgtgatg caaagcgaaa
    12601 ccgctatcaa aatggtagag cttttaggcg gttcgcccgt acctatggga agtgatgaag
    12661 tgtacacgtc tcttcaatcc aatttgatca acggatcaga aaacaatgaa tttgtcttgt
    12721 atacagctgg acatggcggg gtagctaaat actattccta tgatgagcat acacgtgtgc
    12781 cagatatcat catcatgaat gatgccatca aagaacagct aactgatgaa caggaaaaag
    12841 ccattgaaga agcagcgaaa gaatcaacgg tttttgaaat tgaagctttt gcaaaagcaa
    12901 ttgaagaaga aaaagcttta gcacaagaag aacatggagt ccaattcaat gatgtagata
    12961 atacaccgtt tcgagaggca gttgacccac ttcatgatat attcaaaaac gatcctacct
    13021 acaaagacct ttatcaaaag atccaagagc aaggagcgta gctgtaatga aaatgatttt
    13081 aaacaaggta ttagagatcc tgggagctgt tttgcttgtt gggatggtcg ctgttgtttt
    13141 atggcaagta ttttccagaa cggttttagg aaatccaaat acggtcacgg aagagcttgt
    13201 tcgattcggt cttgtctggt ttgccatgtt gtcttccgcg tatgttgtgg gacaaaaagc
    13261 acatttagcc gtaacggttt taagtgaaaa attaactggc aaaaaaagta aaattttaga
    13321 agttgttgtt caaagtttat ttctggtatt tgctgcgatg atcatggtgt atggcggatg
    13381 gaatgctgtc acattgacaa tggggcagat ctcgccttct ttaagtattc ctatgggata
    13441 tgtttatctg tcagtacctg tatcgggggt actcatcatt atctatagcc tgatcaatct
    13501 aatcgataca ttaagcaaca agccagcaat tcaagaaaaa atataaaaat ggaggaataa
    13561 aatggcaata gaagccggat tagtgttatt ttttgtattt gttgtgttgc ttgtattagg
    13621 gatgccgatt gctataagta ttgcattctc atcgatgatg actttattgt tagttatacc
    13681 gtttgatgtt tctgctttta gttcagctca aaaaatggtg ggaagtatca atagtttttc
    13741 gctgatcgct attccgtttt tcgttctctc gggcattatc atgaataatg gagggatagc
    13801 taagaaacta gtggattttg cgatgttgtt cgtcgggcgc gtgccggggg ctttggctca
    13861 tacgaatgtg ttagggaatg ctttatttgg ttccatctct agctcggcca ttgccgcttc
    13921 taccgcgatt ggtggagtgt tgatccctca gcaagtggaa gaaggatatg accggaagtt
    13981 tgcgacagcg gtcaatatcg cgtcagctcc gacaggtatg gtcattcctc caagtactgc
    14041 ttttatcatg tattcacttg ttgctggtgg tgcttcgatc tctgctttgt ttatgggagg
    14101 ttatctcgta ggcgctttgt gggcgctagg aatcatgcta gtagcattca tcgttgctaa
    14161 aaagaataaa taccctgttg tcgaaaaagg acagatggct catgctggaa aaataataaa
    14221 agaggcgatt cctagccttc tattgattgt catcattatc ggtggtatct tgacggggat
    14281 atttacagca gtagaagctt cagcgatagc tgtcatttac aaatgggtta tacgatttta
    14341 gaaccaggaa gtgcttggaa tacgatgcct tgtcatacac atgaacgtcg tatggaagct
    14401 tatgtctatt ttgattatgc caatgaagat acacgtgtgt tccatatgat gggcaaacca
    14461 gatgaaacaa aacatttagt cgtagacaat gaacaagcca ttatttcgcc aagctggtcg
    14521 atccattcag gtgtaggtac aagcaattac tcattcatct gggcaatgtg cggagaaaat
    14581 atcacctata cagacatgga tatggtgcaa atggatcaat taaaataagc ataagggaga
    14641 gaaaatgatg gaatttagta tggatatgtt tcgtttagat ggaaaagtag cattagtcac
    14701 cggtgctgtc tatggtattg gatttgagat tgcacgctct ttagctacag caggagcaaa
    14761 aatcgtattt aataacttga atcaagaatc agttgatgaa ggtatagcgc attataaaga
    14821 agcaggcatc gatgcaaaag gttatgtctg cgatgtgacc gatgaagaag cggttcaagc
    14881 gatggttcaa cagatcaaag aagatgtagg ttcagttgat attctagtca acaatgcagg
    14941 gatcatcaaa cggacaccga tgatcgaaat ggatgcggca gacttccgcc aagtaatcga
    15001 cgtggattta aatgccccat tcatcgtttc aaaagcagtt attccggata tgatcgaaaa
    15061 aggcggcggt aaaatcatca atatctgctc catgatgagt gaattaggac gcgaaacggt
    15121 cagtgcttat gctgcggcaa aaggcggatt aaaaatgctg acgaaaaaca tcgcttctga
    15181 atacggtcaa tacaatatcc aatgtaatgg aattggacca ggttatattg ctacaccgca
    15241 aactgctcca ttacgcgaaa cacaagaaaa cggtgaacgt catccattcg atcaatttat
    15301 cgttggacgt acgccagcag cacgctgggg cgagccaatc gatttggctg gaccatctgt
    15361 cttcttggct tctagcgcat ctgatttcgt taacggccat gtcttgtatg tggacggagg
    15421 catacttgcc tatatcggaa aacaacctta aaagagcttt agtacaccgt ttagtggaga
    15481 ggttgtgaaa tcagcggctt gaacgaatac cgaaggacag ctgattaaac atcatttatt
    15541 cgaaaaaaga ggctgggaca gaagcgttta actccaagaa ataagaagga attcacgaaa
    15601 attgcttttc aaatttttgt gaatttcagc ttatttccga aggagttgct tttgcttccg
    15661 ccgtttatac gtgtttagag cgtgggataa aagtgttctt tacttttgtc ccacgctctt
    15721 ttctgtgcgt cttccatact tcactaagtc gatccctctt gcttcgcacc aatccttcac
    15781 tggtccggaa aagatcagtg attgttggtg tagggccgcg gtattcgttg cgccgaccat
    15841 agtataaagc agacgaagct cttcttgcca ttgcttcatc agtataatag tttcttctac
    15901 gccgtgattc atcagatgcg tcagtacggt tcctgaagta cccactgcat ttgcgccgag
    15961 acaaagggct ttaaatatgt cataggcatt gcggatacct ccggaggcta ggatttccat
    16021 agaagtgtct gcttcatttg cttcaagcaa tgaagagact gtcgattgcc cccagtcagc
    16081 taaataactc agttcccgct tggagcgacg ggcgttttcg atctgggtga agcttgttcc
    16141 gcttcgaccg ctgatatcaa ctgtatgaac tcctaaagca gctagatcat tgagcgtttc
    16201 tcttgtcatg ccaaaaccga cttcttttac gatgaggggg acgtcaatgg ctgtttgagt
    16261 ctcttgaata agtactttcc aattggtaaa atcacggtct ccctcaggca taaccaactc
    16321 ttgaggtgca ttcaaatgaa tctgtaaggc atctgcgtga aacaatcgga tagcttcttg
    16381 ggctctttcg acagaagtcc ctgcaccgat gttggcaatg attttcccgt gaggatattc
    16441 ttgtcgcata atcgtataag tatcggctaa agaagggtct ttcaaggcag cgctgactga
    16501 accagtggca atcatcaaat ctgcttctct tgcgacgatt gcaagatctt ggttgatttt
    16561 ttttgttttt tcgcttccgc cagtcatcgc attgatataa aatgggctgc ttagtgtaaa
    16621 cccaactgcc tgtgtactta gatcgacatc agaaactgct atttgcggca aagggttatg
    16681 gatgatccgt acgaagtcaa attcgttttt ttgtttatca tgaaaggctt tagctagtga
    16741 aacatgttcg tcttttcgat tcatcggttt tcctttcttt gatcgctata gacatgtaac
    16801 ggcagtggag tgatttctgc tttttcccat gcactcatta aaggaaggat gccagatttc
    16861 tggtcaacaa ttacgattcc gcaatcgcca ccacctgcac cagaagattt tgcggctcct
    16921 tcatactgtt cagctaaatt acacaatttg ttcaaagcag gcgtttcgat gacgacccca
    16981 gtgattgcag ataaatcatg cagtaattgt cggttttttc gaatcatctg ttggatcaac
    17041 gttacattat tttctttaaa ccctttgatc atttcgttga cacattctgt actgtttttt
    17101 aagaaaagct gataagccac cattttgtct tctctcgaac ggtgaacttg atcgaccaaa
    17161 tcagaagtag aggcagggct acccgtccaa ccaatcaata aacgtaaatc ttcaggagca
    17221 atcaatggct caatggatag acctggccaa tccagggcaa gtaactcact gatagaatgc
    17281 tgagtttctt gttcttggag ccaaggatgg tcgaaggttg agaaagcgat ccagccacca
    17341 taacagctag cagcgatgtc gccgcaggaa ccattatctt gaactgctaa attggctagt
    17401 gctgcaatct tgaaaatctc caactgagat aaattcaacg cgtaaaaaac attcaaggct
    17461 ttgaccgttg caacggtcac ggcaccgcta gaacccaatc catatttccg gccatttgaa
    17521 ctgtctaact cacttgttac tttcagatca taaaaggata aaagaatgtt tttttcttgt
    17581 gcatactttt cagtcaaacg aatagcagca aggatataat gaaaaggatt ttcccgaata
    17641 tctaaaacta attctccgtt gcgtcttgtc caacgtacag gcatcccact atattgtgca
    17701 gattggatac ttccgacttt tcgtgcggat tctacagtga ctgttacgaa ttgatcgact
    17761 gcagcgataa ctgctggatg tcctgtttca acaactgcat attctccggc aatatagagt
    17821 ttgcctggtg cagatacttc aatcataaaa atctcccttt attcaataat cgcaattcct
    17881 ggaccagcat gggcagtaat tacttgttct ttgctaaata atttggtaaa tgtttcttgt
    17941 acctcagata aatggctgtt ttccactaaa actttgacat tagggccagc atccatcgta
    18001 aagtagcatg gaatgccttt ttttctcaat tgccgcaccg catccatcgc ttttaagctg
    18061 tcaggagacc agtaagtgaa tggaggctgg gcagctaaag tcgttccatg catttttagt
    18121 ccgtttcttt ccatcgtttc tccgagaagt tggaaatctt ttgttttgat tgcttgtttc
    18181 aattgatata gatccccttc aacggaatct aaccagcctt gataaaaact ggatgtttcg
    18241 actgtccgac gcatcccatt tctgctggac acttcttttt tctggtcgtt gatcaaaacg
    18301 aaaaccattg ctaaatcgtc ttcgaaagaa tcggaaggga ctggcttagc gtaagaactt
    18361 aagtcgtcat ggcctttttc ccattcgacg aaaccaccga aaatacttcg gcaagctgaa
    18421 ccagacccgc gtcgagcaaa tcttgaaaga gagagatcgt ctaatccaag cttaagagca
    18481 gtattgcaag ctcctgctaa agcagctagc ccgctggcag aggaggctaa tccagctgcg
    18541 gtaggaacga aattctgact gattactgaa gcttttagtg agaggccggc ttctttacga
    18601 aaaaggtcaa gaaactgact gacttttttt gttgcttttt cgtcttgtaa ggtgccatct
    18661 agataaaatt catctaccat atagctatca gaaaagatga cttctgtctc tgtataaaat
    18721 gcatccaatg ttaacgaaag gctgttgttc attggaagga tgagttcttc atttttctta
    18781 ccccaatatt tgattagagc aatgttggta tatgcgcgtg ctttgccttt aaacataggt
    18841 atgtactcct aatccttgta tccaagtttc agcagcaccc gcatcttcaa gtgcttgact
    18901 gatttcttgg gcttttgttt ttgtttgtgc taatgcaatc atacagccac cgcgtccacc
    18961 gccagttaat ttggcaccca atgccccggt atcttttgct gtttggatca atagattaag
    19021 aaaatcattg ctgattgtca gcttttccag aagtgactgt gattcatcca ttgtctgtgc
    19081 caacgtttct ggtgaattct caatgattgc ttgttttgct tgcttcgtca agtatcctaa
    19141 tttttggatc atttgtccag tttcatgagg ctgggtttca aagaggtgag cgacatcttt
    19201 gacggcttct cttgtttgtc ctttgattcc tgtatcagcg acaatcaaaa aagcatcgat
    19261 gttcaaagaa aagtagtcaa aaggatgccc ttttgtaaaa taaatcggct gcaagctgct
    19321 agtagcggct gcatcgattc cactaggatt accgtgggcg attttttccg aaagctggac
    19381 attttctaat agtatttcac gagacaaagg aaatgctaag taatcataaa aagcacgagt
    19441 gactgctgtg gcgactgcag cgcttgatcc cattccacgt tcagcaggaa tcgtgctttc
    19501 aatggtcagt tgcaagtttt tttggatgtc atgctgtttt tttaagtgaa tgaataattt
    19561 tttgatattt tttaatgcat gaggagcttc ggctaaattt cctgaatagt aggaagaaac
    19621 cagttgatcg tccattgcat ccagctcttc aaggaatgcg gtgacttttg ttgcatagaa
    19681 aggaaaggca atcgctggtt ctccataaac aaccgcgtgc tcgcccatca atatgatctt
    19741 tccgcttgat tctccttggc catagtttgc cataatctaa ctccttctca cgtaaaagtg
    19801 atttttaagc aaaaaataaa gcgcccaaaa cgagttgcgc tgcttcacga atttttttgt
    19861 ccactaaggg tctcaaaaaa cattcctcct ttattttact aaaaccatct cagaagtaaa
    19921 actaagaata cgttttctaa agaaaaaaca cttttttctt aagaattttt tgacttttgt
    19981 tcttctttga ctagaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    20041 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    20101 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    20161 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    20221 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    20281 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    20341 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    20401 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    20461 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttagagcgt atcgaaaaac
    20521 gtggtcgttc gtatgaacaa ttgtcctttg acccaagtct atacgattat tacaaagaat
    20581 tgaacagacg ttatgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    20641 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    20701 tcgaagaaaa attagcagag attcgccaaa ccaaagtatc catttgattt acagttgctc
    20761 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    20821 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    20881 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    20941 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    21001 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    21061 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    21121 ataccgagta cgtgattcga ctaattcgat cgcttttgga acggatgcca gacatgagtg
    21181 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    21241 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    21301 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    21361 aacaaaatgt agtactttta gaacaaatca aggcactggc tatttatcgc aagttgtcag
    21421 aaaaggaaaa agaagagttg gacgatgcac tgatcgaagc acgacaagca gttgaaatga
    21481 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    21541 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    21601 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    21661 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    21721 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    21781 tgcttgctct tgattgacga ttagtcccgc caaagaatct tgagataaag cgattgttgt
    21841 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    21901 taactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    21961 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    22021 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    22081 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    22141 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaac ctgttttttg
    22201 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    22261 ttggttacct ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    22321 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    22381 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagc ctgctaatct
    22441 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    22501 tgctatacta taatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    22561 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    22621 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    22681 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    22741 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    22801 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    22861 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    22921 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    22981 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    23041 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    23101 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    23161 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    23221 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    23281 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    23341 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    23401 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    23461 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    23521 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    23581 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    23641 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    23701 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    23761 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    23821 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    23881 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    23941 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    24001 aagtctaaaa taacataatt aaggtttttt aattgaaaac tgaacattta tggtcatcct
    24061 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    24121 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    24181 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    24241 ttttgtcatc atggctactg tatggatggg attagcgcta gtcggaaaca cgttttcacc
    24301 aaactcggcg atggaagggc aaggagtaat tgatgtgttg acgcatatct atacgacggg
    24361 gccagctgag tacgccaaat cgatcttggt aaatgtcttc tttggtgcct ttttcgggcg
    24421 tgttctagta gatagcggaa tcgcagctac cctgattcga aaggtagttg aacttggagg
    24481 ggacaagcca agaatcacga tgagcttact atgtattgta accgctgtta tattcatgtc
    24541 gatgacagga atcggaccag tgatttctat tgcagttatt gtgttgccga tcttgatgtc
    24601 attaggtatt tcagtaccgg ttgcactgtt ctcatttatg ggctcgatta tggctggaat
    24661 ctttgctaat atcgtcaatt tcaaacaata tcaaacgatt tatgctggtt tcaatccagc
    24721 ggctgaaagc tatacttata atgactattt ccaaattggt atgattggga tgattgtaag
    24781 cttagttgtg gtactaacgg tcgctaatat atcaatgaac aaaaagaaac gctatgcaat
    24841 ggcagcaaac gtaccagctg aaggtggcga cgcaccaatg atctcatggt tagccgtatt
    24901 attaccagtt ttaggggtcg ttcttttaga tcttccaatc atcttaggtt ttattctagc
    24961 aggtatctgg gcattgctgt ttactggaaa attgcgcgga ggttataaag aaatctgtcg
    25021 tcagtttgcg aaattattta cagatggcgc agtcgatgtt gcaccaatgg ttggtttctt
    25081 gatgacctta gcgatgttca ataattcagc tgcgtatgct tctccttatt tttcagctat
    25141 ttttggagat tggataccgc aatcaccatt agtcttggca atcgtatttg ctatattgac
    25201 accactagga tttttccacg gtccaatgaa tctagtcggt tcaggctcag ctattttagc
    25261 tgtcgtgtta gctgttaatc caacgatgtc gccagccttt ttgttcccgt tatttgcaat
    25321 tacaacgatt gctcctcagc atttagatat tacacaatct tgggttgctt ggggattagg
    25381 ttatacaaaa gtaacttctc gagaatatat gaagaaatcc atcccaactg gttggatcat
    25441 cggtgcgatc ttatgcctga tcacgttctt attgtacggg aacgcctagt aaacaaaacg
    25501 tcgataaaaa cgattagata aatggaggaa aagaaaatga aacgttttgt gcgaatggga
    25561 attgatgttg gcggtacaca tacgaaagca gtcgcaatcg ataatgcgac gcacgaaatc
    25621 atcggaaaat cttcagtgaa aacaacccac gatgatgtcc gtggagtagc cgcaggtgtc
    25681 gttcagtctt ttcaaaattg tttgcgggaa aataatatca gtccagaaga tgttgtgttt
    25741 gttgcacatt ctaccacaca agcgactaat gcactgattg aaggagacgt agcaaaagtc
    25801 ggcgtaatcg ggatggcaaa aggtggatta gaaggttttt tagcaaaacg acaaactaga
    25861 ttgaacgata tcgatttagg gaataagaaa aaaatagaga ttgtcaatgc attcttacct
    25921 gtcaaaaact taaatgtaga ccgtgtttca gaaacgattt cttctttaga aagagaaaga
    25981 gcagaggtct tggtttcttc tatggcattt ggagtagata atggggaacc agaacgagtt
    26041 gtttatgaag cagcatctgt gaaagcgatc cctacaacga tggcttctga catcacaaaa
    26101 ttatatggat tgacaagaag aactcggaca gcagcaatca acgcatctat tttaccaaaa
    26161 atgctagata cggcaacctc gacagaagac tccgtacgag aagcaggggt caatgtttct
    26221 ttgatgatta tgcgcggaga cggcggagta atggaaatca atgaaatgaa aaaacgacct
    26281 gttttaacca tgctttccgg tcctgctgca tcagtcatgg gctctttgat gtacttgaga
    26341 gcgtctaatg gtgtttattt tgaagtaggc ggaacaacaa ccaatatcgg ggtcattaaa
    26401 aatggacgtc cagcaatcga ttattcaatt gtaggtggcc acccaacata tatctcttca
    26461 ttagatgttc gggttctagg tgtggcaggc ggttcgatgg tacgggctaa tcagtcagga
    26521 atcatcgatg tcggtccacg ttctgcacat attgccggtc tagattatgc agtatttacg
    26581 gagacagaaa aaatcaaagg tcctaaggtt gaatttttct ctcctaaaga aggagaccct
    26641 gctgattacg tcaaggtagt gatggaagac ggagaagaag tgactattac aaatacatgt
    26701 gcagccaatg ttcttggatt agtgcaagaa gaacattttt cttatggaaa tgtcccatct
    26761 gcacgaaaag ccatacaggc attagcagac tattgtcata cgacggttga agacatcgca
    26821 gagcagatca tggaaaaatc ctatgctaag attgaaccgg tgattttaga attggcagac
    26881 aagtatcact tggagaaaga tcagatttct cttgtaggtg tagggggcgg cgctgcctca
    26941 ttgattactt actttagtaa taaaatgggt gtgaaatatt cgattcctga aaacgccgaa
    27001 gtgatttctt ctattggtgt agcacttgca atggtccgag atgttgtaga acgtatcatc
    27061 ccttcgccaa gtaaagaaga tatacgatcg ttgaaaaatg aagcgatgaa taaagcgatt
    27121 gaatcaggcg ctacaccaga atcgatcgaa gtacacgtag aaatcgatcc acagacttca
    27181 aaagtaacgg ctatcgctac tggttctacg gaagtgaaag caaccgatct aaccaaggag
    27241 atcacaacag aagaagcact agagcttgct gcagaggata tgcgattaaa taaaaatgaa
    27301 gtttgcttat tggaaaatac acctttcttt tatgtatgcg gcgaacagaa tcgttcaaaa
    27361 aatgctggaa gtcttcggat catcgatcaa aaaggattta tcaaggtcca acgtggacat
    27421 gcttcatgta tgaaaacaac tgcagccaat tatatgacag ctgtcgaaca actttgggaa
    27481 gatatggcag tttatcaaac tgaattgatt gcccgaccag aattttatct ctgcttagga
    27541 gcaagagtct ctgattttac agcgacggat ctggaacaac tacagctttt gatggatctg
    27601 gaagtatcta ctatggaacc ggaggaagaa gtgatcgtcg ttgccggaaa tatcaaacaa
    27661 acataagtta gaagagttac taaacgaatt acaacagatc cccgaagaaa tttggggatt
    27721 ctaccagttt cggcgagatt tattttggaa aaagattcct ttgtccaagc agaaaattct
    27781 tatacaacaa tcaatcgatt gtggtatcga aacggcatgt agcatcaaaa aaaagtaccc
    27841 ttttgccgat gtaggagaaa tctgtgaaca aatggctgtt ccaatcgttt cctgtgaatc
    27901 agagcaaata aacgaacgaa tcacttttgt aacttatgca gaagatgaag ggatccgatt
    27961 gatgacggag ccgttagaaa aattaaaatg ttcaggacta gcttcgatct ctaaagaaac
    28021 agcgcaagct ttgattattg gacatgaact atttcaccac atcgaagctt ctgttaaggg
    28081 aatttatacg caaagcgaaa aaattgtgct gtggcggttg cctttttata cacatcaatc
    28141 aaacattcgt gcattgagcg agatagcagc gatgagtttt tcaaaagaga tgaatcaaag
    28201 cgatttttcg ccttatgtat tagaggcagt cttactttgg ccatataatg aaattcgtag
    28261 ccaagggatc ttagaagaaa taaaagaaat agaaaaaaga tgtacggagt atgatttaga
    28321 ttacaaataa agagactgtg acaaaagtcg tgtcacagtc ctttttttcc gaataaacgg
    28381 tgttctcctg tcaactcctc ggtcacaagt caaaatattc aacaaacatg agaagctgtt
    28441 ttttgaaatt gttccttgtg actcggagat gaacggcagg ctcacgacct cttggaaaaa
    28501 ggtgttcaaa agcttgcatc tgcggtaata agaacagcca agttaaaaac ataagaagct
    28561 atttttactt ggctgttctt attacttgat gcagggcagc tttttcacaa cctctcaata
    28621 aacggtgtgc aatcagctga ccctcggtat tagctcaaaa aaaacggcaa aatatgagga
    28681 actattttgc cgtttatttc tctaatactc aggtcaaaac gctgattcca aaacctctta
    28741 tttgatgggt ctgtcctgaa tatcttcaaa ataatcgggg taattatgaa tcacgtattc
    28801 ttgctcctcg ataatcatat gtaaatgcat cgtgcaaaga aatccgactt catcaaagtt
    28861 atgatcaatc attgattgaa gcattgtctg atgttcatct aatactcgac cccagtctaa
    28921 ttctgaaatc gtcaaacgta accatctgaa acggttcaag tgcgtactat aactttctag
    28981 ccaatcccaa atttctcgtt ttccagcaat ttcataacaa gttcggtgaa aatcagtatc
    29041 caaatcaaaa aaagcttttt tattttgagc gatcactgcc tgatcggttt gttctagtat
    29101 tttttctagt ttagcttgat cttgcttggt cattttcgca ctgcattctt gcaggatcgg
    29161 tttttccaac ttttcccgcg tataacgggc taatgaagca gatcggatat cgatttttga
    29221 aacataagtg ccggactgtg gaatggtttt tacaagctct tgattgcgca gttggatcag
    29281 tgcttctcga atcggtgtac gcccgatagc tagttgttct tctaacactt tatcggagat
    29341 tttacttcca ggtgctaact cggaataaat gatttgttta cgtatagatt cataagcttg
    29401 ctgttgcaaa ttattgataa ccatttaacc ttcctttcta tgcagatata atctattata
    29461 acataaatcg cttacaaatc gtgtgggcat aaaaacacag tctgcaaaaa aagccctgat
    29521 aggcatgcct attagagcct cgaaaagaaa aatattgaat caatctggtc gtacctcttg
    29581 gatcggtttg acacgaccgc cgattctttt agcaaaagct tcggattctt ttttgtcttt
    29641 gaaaatgagc agattgtcta agtttttttc ccgagtgcga cagccagttt tatcgatgta
    29701 accgtgcatt actttaacga catacatggg gatcacctgc ttttttcttt tcattatacg
    29761 aactactcga cacaatacaa gaaaaatgct tagacggtct ttattaagaa tttacatcat
    29821 ccaaagaagc gtacgcttgg aataactgtt ctaactccgg attgactttg ctcagcttca
    29881 ctaatcgttg cgaatcagaa agtaaaaaac agtgtttact actgccagta gtttttaatt
    29941 ttttgtcttc agttcccaca atttcgtagc taaaatccaa ccgtgttccc gtatactttt
    30001 ggatagttgg gtggatgctc actttttctc cgtaatggat catttcttta tagctgcaat
    30061 ttacttccag aacggggatg atgatcccag attcttcgat ttttttatag ggaaacccta
    30121 gatgtaccaa taaggctacc cgagcctctt caaaccagcg gatataattg ctgtgatgaa
    30181 taatccccat ttgatctgtt tcataataaa aaggttctcg cacataacct gtaaatttct
    30241 ccatgactca tgcctcgttt tccattgatt ttttacaaaa ataattcatc cacttcggaa
    30301 gtgcttcgct gatttgtgtc ggcaaaacaa tatattgttc ttttgccagc tggtctccaa
    30361 tgaaactatg aagataaaca gctgctgcaa tcgtttggtc attttgagga aactgggcta
    30421 aaaatcctgt gatcatccca gctaaagtgt cacccatgcc gcctgttgcc atagcagcag
    30481 aacctaaagg attggtgtag aagtgctggt gaccataaat ttttgtctca tgacttttca
    30541 aaacgagcac agcaccgatt tcctgttgct tctttttgtt ttctttatcc cgttgttctt
    30601 gtatcggtag agaactcaac cgttgccact ccatttgatg aggtgtaagt acagtttgtt
    30661 cgggataggg tagcaaaaga tgattagcaa caagtaaact taaagcagag ccatcaatca
    30721 ccagccattg ttcttttgat tgtttttcta gtacttgttt gaaacgttcc aaactcttag
    30781 aagaagtacc caatccggga ccaatcaaga gtacatctgc ttgctttatt acggaaagaa
    30841 actggtcagt atccgtccaa tctacaatca ttgcttctgg cagatgactg tgaagagcac
    30901 tccgattttt ttcatcagtt actacagtcg tgagacccgc tccactgtgt acggcagcta
    30961 aagcactcat aatgattgct ccgccatatt gttcattgcc gccaatcaaa acgatacgtc
    31021 caaatgttcc tttatgtgaa atttttggac gaggtgtgat gactcttttc actagttgtt
    31081 cgtttatcag catcgaaaaa cctcctttta ctcattatag cgtatatttt ttttagagaa
    31141 aaacagataa gaaaaggaat tgtcagattt tttgaactat ttttttctgt aatttgtggt
    31201 atcatgaaca cgaagactta aataagtgga ggattaactt tatgacaatt gattggcaaa
    31261 aagaagtaga agcacgtaaa gaagacttgc ttgaagactt gaaaaatctt ttacgtgtca
    31321 acagcgagcg cgatgattca aaagtaacac cagatgcacc atttggacct ggacctcgcg
    31381 acgcattgaa acatatgtta gcttatggcg aacgtgatgg atttaaagta aaaaatgtcg
    31441 ataactatgc agggcatatt gatcttggcg aaggagacga aacgctaggg atatttggac
    31501 acatggatgt cgttcctgca ggagatggct gggacacaga tccttatgaa ccagtaatca
    31561 aggatggaaa gatctttgca cgcggatcaa gcgatgacaa aggtccaagt atggcagctt
    31621 actatgcgat gaagatcatt aaagaacttg acttgaaact atcaaaaaaa gttcgcttcg
    31681 tagtcggcag cgatgaagaa agcggctggg gcgatatggc ttattatttc gaacatgaag
    31741 aagaaccaga ttttggtttc tcaccagatg ctgaattccc aatcatcaat ggtgaaaaag
    31801 gaaatgtttc tttagcttta cgcttcaaag gcgacaatgc aggagattat gtcttgaaat
    31861 cttttgtttc cggacttcgc gaaaatatgg tgccaggaac agcaactgca gcacttcaag
    31921 taccaagtgc agatgcagct atcgcgatgg aagaagcatt ttaccaattc atcgaagcaa
    31981 atccagtaag cggaacgatt gaagcggaca atacgtatgt aaaaatcgaa ttagttggta
    32041 aaggcgcaca tggtgcaagc ccacaatctg gtatcaatgc aggttctttc ttggcattgt
    32101 tcttagataa ctatgaattc ctaggatctg ctaaacaatt tatccatgta gcagctgctt
    32161 atgtccatga agatttttat ggagaaaaac taggagtcgc ttatgaagat gaaaaaatgg
    32221 gcaaattgac aatgaatgct ggactatttg cttttgaaga aaatggtaca gaggaagcga
    32281 acttcatcaa tatgaatttc cgttttccaa aaggtgtaac agtagacgga ttgcaaagtg
    32341 acatcgaaca aacagtgggg caagaaggcg caacagttac tcgaggtgct cgcgtaatgg
    32401 aaccacatta cgtaccaatg gatgatccat tggtggctac attattgcaa gtctatgaag
    32461 accacactgg agaaaaaggc tacgaacaaa tcatcggtgg cggaacttac ggacgtttgt
    32521 tgaaacgtgg cgttgcttat ggagcgatgt tcccaggata tactgataca atgcatcaag
    32581 caaacgaatt tatgagtctt gatgacttgt tcagagcaac agcaatctat gcagatgcca
    32641 tctatcgttt ggcgaaataa aaatactaaa aaactccggc tatctctgac agctggagtt
    32701 tttatgttta aaaatgaatt agtacatcgg tattcttaaa agtaatttag ttcgtctttt
    32761 gatttctcag gagggatcaa aaaggcgaaa gcactaagta tagcaaaact tgtgatgatt
    32821 tgcgtacgat acgtaaacca ataatgaatc tgtgagtgat tagctaaaat attgtaccaa
    32881 atatacggcg ttacagcagc taaaacaaac aaaactagaa gttggaacgg acgccagcta
    32941 tttcgtttac gataagcaaa atagagaaaa acaagacaag taatcaatag caataatatt
    33001 gctacttttg gatacatcaa tctaatattg cttttcagca tctctaatcg atgcaacggg
    33061 tatttgtcgt ttccttccgt tcgaaagagg atttggttga ttgcatcttt tacaatgttt
    33121 ttgttcaata tgatcgatga taggatccat ttagccaccc atgtcaaacc atagcctaat
    33181 ccccaaaaga taccggtaaa aacaaaactg cctacttgtt tgctcaatga actgcgttta
    33241 tccattaaat acttatttgt tacataataa ataatgatca caggtatccc ccaagagatg
    33301 accggtgttg tcaacaagtc aaaaaagtta gctaaagaac caatgacaaa gaaatacaag
    33361 aataattgtt ggttggtgtt ggagagttgt ggttttgtta aaaatagtaa tacagacaat
    33421 aaagtcaaaa tccaaatatt tgaaaattgc atactgaaga aaaaggttgc agcatttcct
    33481 atagcaagcg aaatcaacaa ggctgtcgtt aaatagatgt cgctacactt ggttaaaaag
    33541 tagctcgtca atccaatcag cagaaaaaga atggctgcgt aaatcattcg aatactcccc
    33601 aaactcatcc ctagcagtaa aggtcgtaaa aaaagctgat aaccatgcca ataacgggga
    33661 taatccgcca tagacatcgc gttctccaag gagttcaatt caggatctgc ttttgttttt
    33721 cgtatcatca aatgatcagt aaaattatct aaccgagtgc ctagcatatt tccttgattg
    33781 atagaaggat acattccttc tttttcaacc atctgtagag atttttctgc attcgattca
    33841 atagagtgct gcggaatgaa aaaagtaatt gtcagtagta cgcaatagct agcgatcaag
    33901 agaacaaaag caaaaaatat ctttttaaat agtttcatga gtatctccta tatctgtttt
    33961 cattttttct cttttatcta gtaaaaaagg agagaggata taaacaggta gacctaatgc
    34021 taaaacaaac acataccgta aactaaaagc cacaggagta gcaatcataa tagtagcaaa
    34081 aacaagcata ccgggaagaa aaaggagtaa ataccgatat tttttcttaa agattgctaa
    34141 aagtgcactg ccgatagcta accacagtaa tgtgccggaa ccaaagaaat cacgagcatc
    34201 gatgattttt ttcattcctg acaatccagt aagatgttca atcaaatcta cttgcttcat
    34261 cccataatta ttcgtgttta cacgagtatc taaaaagccg taactatttt ttgtaccagg
    34321 tacccagaac ccgaacgttt ctaaaatata agcatctgta tagattttta tattacttgg
    34381 taaatttctt gcccatagtg atagaaattc ttttttatgt gtattcaaaa actcattgtt
    34441 aaaattttta tgccacttga ttgagtctgc aagactagga gaatacgctt cataatcttt
    34501 tatcgggagt agctgattca tgaatgcttt atctttctta gacaagtcac catccataac
    34561 aatagttcta gaaatttgct gcaaaggaac acctaattgt tcagcagttt ctgtaggaat
    34621 agcataacga gccatcaacg ggtggatgag tagtccagca atcactgtat aacccagcac
    34681 cacttgaaag aatgcttgat accttttttg tttcaaaata atcaagccgc aaatcaaacc
    34741 tgtgccggtt actacataaa tcccattatt tcttagatag gtggtcagta aagcaaggat
    34801 gattacgtaa atctgattga gaatcgttgg cttttctcgt tgaaaaataa agtcaaaaac
    34861 cgctaaggaa aataaaaagc aagcgataga gaacaaagta tctttttgca tgttcaaggc
    34921 gtagattgga aaaaccggtg caaatgcaaa atagcataaa ctaatgagta ccggaaaaaa
    34981 atggatgttt ctttttaaca gccagcaaag agaataactt atcgctgaag ctgttatcaa
    35041 tgtttgaaaa atcgaaaata aaaatacacc gtgattgatc gtatcagttg gtaaatcatg
    35101 aacaaatagc ttgaccagta aggtgaataa gactggatga tgattgctta taggaacatc
    35161 acccatagat tgggcgaccg aacttaacga atcaggcaaa accactccag gatacaatgc
    35221 caacagataa ggaagccaac acagaactaa aaagacagta aagaataaaa aatattttct
    35281 tgaagagaaa gcctgtgtgt tttgagcagt aaaaaatgtt tccagttttg gcattgataa
    35341 ataaatcgat tgtaaaaata aaaaagaata cacaaaaatg gagaaataaa caagaaagta
    35401 aaaaatactt ccatcagcaa tcgttgtctt tgtatagttt gctgagacat actgaaattg
    35461 tatctgtctg ccaatagaaa gtgtaagagc aaaagctgca gaaaaaaaca atcgggcaat
    35521 agctgcaact ttgtttttta ttgaaaacaa ctctattcca tattgcttaa aagcaagtag
    35581 caaaaccatg gctaaaccaa tgattactgt tggattcaaa gttcctagac cataagaagt
    35641 aaaaaaagca aaacctgacg caaataaagt tgcaaaaaaa gtaggaaata gattctcctt
    35701 tttcttatgc ataaaaaagg cctcctactt catttcttta ttttgatatt cgtggtagac
    35761 atggtataaa ttcaattcat attctttctt ggcatttgtg acgaccgtat ccaaaatcaa
    35821 ccctgttact aatgaaagaa gggctaaagt catcaatcca gtacttaaaa tcgcagaagg
    35881 gatgcgtgta ataaagcttg tcagcatata ttcacgaatc acaggaatcc ccatgaccaa
    35941 tccaaataaa aagaagaaga tggtccagat cccaaagaaa agcaaaggtt tataatcttt
    36001 gcacattttg atgatcatca tgatcacttt gaatccgtca gagaatgtat tcaattttga
    36061 ttcgctacct tcaggacgat cgcgataatc gattggaatc tcaacgaact tgaatttttt
    36121 atctaaagca tgaatcgtca attctgtttc gatttgaaaa ccagaactca taatagggaa
    36181 gcttttgaca aaaattcgat tgaatcctcg atagccggtc atgacatcgc gaatttttgt
    36241 tttatataag taagtaattg tatttttaac cagattattc ccaaaatcat ggaaaggacg
    36301 cttattttca tcaaaatagg ttccatttga tagacgatcg ccaatgacca tatctgcttc
    36361 gccagaacgt aatttctcaa gcaaaccatg tgcagcttct gcaggataag tatcatcacc
    36421 atctaccatc aaataataat cggcatcaat atcaaaaaac atttgacgga ttacatttcc
    36481 ttttccttga cgtggttctt tctttacgat tgctccacct tgaacggcca attcgtatgt
    36541 tcgatcggtc gaattattat catagacata aatatctgct tctggtaatt cccttttaaa
    36601 atcttcaata acagttgaaa ttgtcgcctc ttcgttataa caaggaatga gcacggcaat
    36661 tttttcacgt gattccattt gtcactctcc ttatataata aaactaatct tatttcaaga
    36721 ataccgtata ataactataa atactagcta ttccaagagg aaatagccct atttttataa
    36781 aaattaccca ctataaaaga agtataggat acctctcttt tgaatagtgg gtgcgtattc
    36841 gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa atttctaata
    36901 cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca tcttctattc
    36961 gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata ggttcctttt
    37021 caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac ttgatatttt
    37081 caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt gaagctaccc
    37141 cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag cttagttcgc
    37201 tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg tgcttatttt
    37261 accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat aagctataat
    37321 aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat aagtctgaga
    37381 ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt caacgaatca
    37441 aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc gcttatatgg
    37501 aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc ggcatttttg
    37561 gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca catatggatg
    37621 aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc gtacctctag
    37681 gcggctggaa tccttacgtt gtttctgcac agcgttttac acttaaaacc tctactggta
    37741 agaattatcc atgtatttct tcttccgttc ccccgcattt attgcgagga acaagcggac
    37801 aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca agagaagagg
    37861 caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa acgatcaaaa
    37921 cagccaacgg aaagaatatc atcagcaaat catgggacaa ccgctatggc tgtacaatgg
    37981 tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg attgcaggcg
    38041 cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat aaattcaagc
    38101 cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg aaaaatggca
    38161 cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt ttgatcatgc
    38221 ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc ccttatcaat
    38281 actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac gaaggaatcc
    38341 caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg atgttcagta
    38401 ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt ttggataaat
    38461 caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata aaatctggca
    38521 aaagattgct tttgccagat tttttttata aaaagaggat caatgtttgt tagttcgaaa
    38581 gaaaggtgta taatttaatt gaaaaataca taaacagaaa gtagaggaca aagaatgatt
    38641 atcccaaata gtttagaaga attagcaggc tacgtagaaa ctggaaagag tgtatttttc
    38701 tttactgcca gctggtgcgg agactgccgt tttatcaaac cgcaaatgcc tgaaattgaa
    38761 aatgactttt ctgattggca atttattgaa gtagaccgtg acaagtacat agatgtagcc
    38821 gctgaatgga acatttttgg tatcccaagt tttgtcgtga tccaagacgg aaaagaatta
    38881 ggtcgtctag tgaataaaga tcgtaaaaca aaacaggaaa tcgaatcgtt cctagaaagt
    38941 gtaacaaaag gctgacatct gttaggaggg gtcaagatga atcaagaata taagaacatt
    39001 ttagtaggta tcgacggtag tgaacaagca cttgctgctt tcaaaaaagc ggtagaagtg
    39061 gctcgccgta ataatgggaa agtatatgta gcaaacgtaa tcgatcagca attttataac
    39121 tttatgggct atgcacctat tgatcaaaat ctagtcgatc agcaaactga aacagccaag
    39181 caaatgatcg aagaatgtaa agaatatggg aaatctgttg attacacaaa tatagaagga
    39241 attattgcat atggttctgt tcgtgaatcc atggcagtca aattgccaaa aaaatatgca
    39301 atcgatctaa tcatggttgg gcagtcaggt ctaaatgcag tcgaacgctt tatgacagga
    39361 agtgtagcca gctacgtgat acgtcattca ccttgtgatg tcttgatcgt ttctgacgaa
    39421 gaagaacagc caagtaatta agcaagtgga acttgtacga cctttttaat caattaacta
    39481 aaaaacagta aagggactgt gacaaaagtc ttgtcacagt cccttgttac gaataaatgg
    39541 tgttccagaa gaggcttctt cggaaataaa gcatgaaaaa aatctcatgc agtgaatgca
    39601 attttttgtt aagataaatc tcagcaaagg ataatggagg aaagaacatg atttttgctt
    39661 ataacaaagc acacgtcgga gacaccttga tggttattat agccgacgat aaaggaacag
    39721 aaaacaccgt tgaacgcaaa tggaatgttg ctcggatcaa agatgaacaa ggacaagttg
    39781 ttgcttggaa ctttttccat atctccgatc atctaacaat cgaagggaac ggccaagtaa
    39841 gcttaacaga tgaggaatta gcgaaattga atcgattgat caaagaagca ggattcgaag
    39901 aacagcttga agctgatcat gaaccgaaga tcgttgtcgg gtacgtaaaa acatgcgtcc
    39961 cacatcctga ttctgaccat ttatcgatta ctgagacaga agtagacaat ggtacagtat
    40021 tgcaaatcgt ttgcggtgca cccaatatcg aagctggaca aaaagttgtc gttgcaaaac
    40081 caggagctat gatgccagat ggaatgatga tctggccagg aactttgcga ggggtagata
    40141 gctatggaat gatctgttcc gctcgtgaat tgcatttgcc aaatgctcca gcaaaaaaag
    40201 gaatcttagt attgcctgag gatgccgtag tcggagaagc atttccaaaa taaagaggtt
    40261 gtgacaagtc tttgtcacaa cctctttttt attaattttc actattttga ttttgtttta
    40321 atgccgattg atcgatcgtc aattcaacag tagttgtttt ttctttcgag ccttcatagt
    40381 aagtgatttt gacagaatct cccacttttt tcttatacaa agcagattga agttctacac
    40441 cagaagaaac ttctttgtca tcgatcttag taatgacgtc gtattgtttc aatccagctt
    40501 tttcagccgg tgtagctgtt tggacatttg tcacgatgac accgttagtt acagatgaag
    40561 gaatcttcaa gatttgttct tgttgctgag tagaaacggc agataagtcg accattgtga
    40621 tacctagagc tggacgtgtc acttttccgt ctttttccag ttgattgatg atattcacta
    40681 catcgttact tggaatagca aatcccattc cttctacgct tacattagaa gtagattcag
    40741 aagtacttgc gatcttactt gagttgatac cgataacttg tccttcgata ttaactaaag
    40801 gaccaccaga atttccaggg ttgattgctg catctgtttg gatcgcattg atattgactg
    40861 tttcgttcga ttcattcgta cttgtcactt gtcggttcaa ggaagaaatg attcctgaag
    40921 tgacagaatt tgcatattca gatcctagtg gggaaccaat cgcaatcgca ggctcaccaa
    40981 ccttcagagc acttgagtca ccaaaagagg caactgtttc gactttgtct gaattgatct
    41041 tcaacaccgc taaatctgaa taagcatctg ttccaactaa ttcagctttt accttcgtac
    41101 cgtctttcat caagacttca agaccttgct ggccatctac tacgtgatta ttcgtgacta
    41161 cataagcagt attcccgtct tttttgtaga tcacgccgct tccttcacta taagcttcca
    41221 aattactatc atctgagctg ctactttctt cttgctgccc gaatagtccg ccaaaaccgc
    41281 ttgattggtt ttgactttgt aagttgataa cagaaacgac agcgtcttga actttatcta
    41341 ccgctttggt gatatcagaa tctacattga ctttgacatt ttccacaact gtttcaccgg
    41401 cagaattctg attgccgctt gtagcagtag aactattgtt gccagtgccc atcgctgcat
    41461 aaaaaatgcc agctgtcagt agtcctccaa cgatccctcc aacaagcccc agacctaact
    41521 tacgccagag gctattattt ttattttttt tcatctttgg tgtcacattt tttctatcca
    41581 tgtgttcctc ctccaattac attcatttat ctactgttag tatactctta tttgttgact
    41641 ttagtctact ttgagactgt gaacttttta tgaaaaactt taggaaaaac cattgttttc
    41701 agatgaaaat atttgatttg cttttttcca aagaaactgt gtaaaactac gcggatagga
    41761 ttggaaaaat aagggataaa acatatccac agcctgtgta taaagtggat aaattcttat
    41821 aaaacgtatg tttgcctaat gaatgtgatg aaataaggta aaataacact gttttctgtg
    41881 gataaacctg tggatgttgt gcataactgt tggggaaatc tttttaacaa aaatagccaa
    41941 aataaacata tagacgaaaa aattgattat aataaacaaa gtgagcatga agaccaaagg
    42001 agagaaaaca tgaatatcaa aattatttca gtaggaaaat taaaagaaaa atacttgatc
    42061 caaggtatca atgagtatgt caaacggctg aatgcctatg caaaaatcga attgatcgaa
    42121 gttcctgacg aaaaagcccc ggagaattta agtgaagcgc aaatgagaca agtaaaagaa
    42181 aaagaaggag aacggatctt agcgaaaatc aaagaacaag aatatgtcta tgccttagca
    42241 attgaaggga aaaatcccac aagcgaatct tttgctaaac aaatcgacca attaggtatc
    42301 caaggaaaaa gccaccttgt ttttgttatc ggcggctctt taggactcag cgaagccgtc
    42361 atgaaaagaa gcaatgctca gatctctttt ggcaaaatga cgtatccaca tcaattgatg
    42421 cgtctgatcc tcgtcgagca aatctaccgt gcctttcgga tcaatgcggg ggctccatac
    42481 cacaaataat gatatttttt aagagaaaaa ttatcc
//
LOCUS       DAIGUC010000021        41979 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.021, whole genome shotgun sequence.
ACCESSION   DAIGUC010000021 DAIGUC010000000
VERSION     DAIGUC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.021"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            134..409
                     /locus_tag="NOB46_001180"
     CDS             134..409
                     /locus_tag="NOB46_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HCI1058130.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            415..1182
                     /locus_tag="NOB46_001181"
     CDS             415..1182
                     /locus_tag="NOB46_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HCI1058131.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            1350..3179
                     /gene="typA"
                     /locus_tag="NOB46_001182"
     CDS             1350..3179
                     /gene="typA"
                     /locus_tag="NOB46_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCI1058132.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            3440..5212
                     /gene="recQ"
                     /locus_tag="NOB46_001183"
     CDS             3440..5212
                     /gene="recQ"
                     /locus_tag="NOB46_001183"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HCI1058133.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            5326..5628
                     /locus_tag="NOB46_001184"
     CDS             5326..5628
                     /locus_tag="NOB46_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HCI1058134.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            5631..6794
                     /locus_tag="NOB46_001185"
     CDS             5631..6794
                     /locus_tag="NOB46_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI1058135.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            6820..10248
                     /locus_tag="NOB46_001186"
     CDS             6820..10248
                     /locus_tag="NOB46_001186"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCI1058136.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            10269..11393
                     /locus_tag="NOB46_001187"
     CDS             10269..11393
                     /locus_tag="NOB46_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058137.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            11383..11820
                     /locus_tag="NOB46_001188"
     CDS             11383..11820
                     /locus_tag="NOB46_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI1058138.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            11804..12142
                     /locus_tag="NOB46_001189"
     CDS             11804..12142
                     /locus_tag="NOB46_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HCI1058139.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            12261..12821
                     /gene="rsmD"
                     /locus_tag="NOB46_001190"
     CDS             12261..12821
                     /gene="rsmD"
                     /locus_tag="NOB46_001190"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCI1058140.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            12818..13309
                     /gene="coaD"
                     /locus_tag="NOB46_001191"
     CDS             12818..13309
                     /gene="coaD"
                     /locus_tag="NOB46_001191"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCI1058141.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            13299..14342
                     /locus_tag="NOB46_001192"
     CDS             13299..14342
                     /locus_tag="NOB46_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HCI1058142.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            14501..15229
                     /locus_tag="NOB46_001193"
     CDS             14501..15229
                     /locus_tag="NOB46_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCI1058143.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            15345..15590
                     /locus_tag="NOB46_001194"
     CDS             15345..15590
                     /locus_tag="NOB46_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI1058144.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            15587..15805
                     /locus_tag="NOB46_001195"
     CDS             15587..15805
                     /locus_tag="NOB46_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCI1058145.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            15941..16480
                     /locus_tag="NOB46_001196"
     CDS             15941..16480
                     /locus_tag="NOB46_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HCI1058146.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            16473..18746
                     /locus_tag="NOB46_001197"
     CDS             16473..18746
                     /locus_tag="NOB46_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HCI1058147.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            18784..19830
                     /gene="holA"
                     /locus_tag="NOB46_001198"
     CDS             18784..19830
                     /gene="holA"
                     /locus_tag="NOB46_001198"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCI1058148.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(19919..20173)
                     /locus_tag="NOB46_001199"
     CDS             complement(19919..20173)
                     /locus_tag="NOB46_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCI1058149.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(20573..20842)
                     /locus_tag="NOB46_001200"
     CDS             complement(20573..20842)
                     /locus_tag="NOB46_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058150.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(21312..21767)
                     /locus_tag="NOB46_001201"
     CDS             complement(21312..21767)
                     /locus_tag="NOB46_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCI1058151.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(21905..23833)
                     /locus_tag="NOB46_001202"
     CDS             complement(21905..23833)
                     /locus_tag="NOB46_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI1058152.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(24030..24863)
                     /locus_tag="NOB46_001203"
     CDS             complement(24030..24863)
                     /locus_tag="NOB46_001203"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCI1058153.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(25055..25759)
                     /locus_tag="NOB46_001204"
     CDS             complement(25055..25759)
                     /locus_tag="NOB46_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1058154.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(25782..26408)
                     /locus_tag="NOB46_001205"
     CDS             complement(25782..26408)
                     /locus_tag="NOB46_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1058155.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            26734..29109
                     /locus_tag="NOB46_001206"
     CDS             26734..29109
                     /locus_tag="NOB46_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCI1058156.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(29133..29624)
                     /locus_tag="NOB46_001207"
     CDS             complement(29133..29624)
                     /locus_tag="NOB46_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCI1058157.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            29811..30731
                     /locus_tag="NOB46_001208"
     CDS             29811..30731
                     /locus_tag="NOB46_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1058158.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            30885..31229
                     /locus_tag="NOB46_001209"
     CDS             30885..31229
                     /locus_tag="NOB46_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HCI1058159.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(31419..31919)
                     /locus_tag="NOB46_001210"
     CDS             complement(31419..31919)
                     /locus_tag="NOB46_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058160.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            32447..32530
                     /locus_tag="NOB46_001211"
     tRNA            32447..32530
                     /locus_tag="NOB46_001211"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32481..32483,aa:Leu,seq:cag)
     gene            complement(32854..33492)
                     /locus_tag="NOB46_001212"
     CDS             complement(32854..33492)
                     /locus_tag="NOB46_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1058161.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            33827..34261
                     /locus_tag="NOB46_001213"
     CDS             33827..34261
                     /locus_tag="NOB46_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI1058162.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            34284..34604
                     /locus_tag="NOB46_001214"
     CDS             34284..34604
                     /locus_tag="NOB46_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058163.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            34745..34936
                     /locus_tag="NOB46_001215"
     CDS             34745..34936
                     /locus_tag="NOB46_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058164.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(35007..35264)
                     /locus_tag="NOB46_001216"
     CDS             complement(35007..35264)
                     /locus_tag="NOB46_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCI1058165.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            35422..35685
                     /locus_tag="NOB46_001217"
     CDS             35422..35685
                     /locus_tag="NOB46_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058166.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            35709..35897
                     /locus_tag="NOB46_001218"
     CDS             35709..35897
                     /locus_tag="NOB46_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058167.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(35980..36165)
                     /locus_tag="NOB46_001219"
     CDS             complement(35980..36165)
                     /locus_tag="NOB46_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058168.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            36380..36751
                     /locus_tag="NOB46_001220"
     CDS             36380..36751
                     /locus_tag="NOB46_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1058169.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(36901..36973)
                     /locus_tag="NOB46_001221"
     tRNA            complement(36901..36973)
                     /locus_tag="NOB46_001221"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36938..36940),aa:Gln,seq:ctg)
     gene            complement(37019..37447)
                     /locus_tag="NOB46_001222"
     CDS             complement(37019..37447)
                     /locus_tag="NOB46_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058170.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(37507..38265)
                     /locus_tag="NOB46_001223"
     CDS             complement(37507..38265)
                     /locus_tag="NOB46_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCI1058171.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            38560..38757
                     /locus_tag="NOB46_001224"
     CDS             38560..38757
                     /locus_tag="NOB46_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058172.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            38863..39345
                     /locus_tag="NOB46_001225"
     CDS             38863..39345
                     /locus_tag="NOB46_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058173.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(39403..39999)
                     /locus_tag="NOB46_001226"
     CDS             complement(39403..39999)
                     /locus_tag="NOB46_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI1058174.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            40386..41852
                     /locus_tag="NOB46_001227"
     CDS             40386..41852
                     /locus_tag="NOB46_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HCI1058175.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        13855 a         7149 c         8500 g        12475 t
ORIGIN      
        1 aaaaatcagt tgcgttttgt tttttagaat tatcaataat attattatgt aaacttaaaa
       61 atatgacaac ttcttggttt attaccactt cctatgctac actgaagagg aatatgaaat
      121 aggagagttg aagatgcaag aatatcagta tccacttgat ttagattgga caacagacga
      181 aatggtcatt gtaatgaaga tgtgggaaga tctggaacgt gcgaatgaaa aagggataaa
      241 caatgaagct tttttgaaga cttatcagca gtttaaaact gttgtcaaat ccattggtga
      301 ggaaaaacga ttgggacggg aatttgaaaa agcttccggt tattctttat atcgtacagt
      361 gcagcaagca aaaaaaaatc caaacaaaac tttgagaatg aacgggtgag ataaatggaa
      421 cagatgattg atcatatcaa gtcctggctt gaagaagctg gtgagaaaat caaatcttct
      481 caacaaacat taacaatctc gcaaaaatca aatcgaacgg atctagtaac aaatgtcgat
      541 cgaaacatcc agaattttct aatcgaaaaa atccattcct ttgatccaga ggcgaaaata
      601 ttggcagaag aagaagggtg taatcaatta tcggatctcg atggaagagt ctttatcatc
      661 gatcctattg atggcacctt gaattttgtg attgaagggg aaaatttttg tattatgctc
      721 gctgtttatg aatccggcgt tggaaagctt ggtttcattt atgacgtgat gagaaatgaa
      781 cttttttggg gtggaaaagg aataggcgtg tataaaaatg atgagccatt gcctagacca
      841 gcaaataaat ccttatcgga aggcttactt ggtgtgaata gttatctttt cggtcataat
      901 aaatatggaa tccgagaaat tgcggaaagc agcatgggga cacgtatgta cggatgcgct
      961 ggtcttgaac tagtggcaat cttgaaagga aaccacattg cttatatttc aaaccttagc
     1021 ccttgggatt atgcagcggg aaatgtctta ttggaagagt ttggtatggt aacaagcggt
     1081 ctttttggta ctcctttgac atttgaaaaa agggaatact atttagcagg gacttcttgt
     1141 gcatatgcag aaatcgcaga ccttttgaaa aaagaaggct gaaaaaaagg tagaaatcat
     1201 tcacaaaaat gataaaaacg agcaaaagat taattttctc gaaaaaatga aaacatttta
     1261 ctatatttca tgaaaaaagt ctgctataat tagcagtcga gtaaaatttg ccctgtcata
     1321 aagaaccaat aaaaaaggag ttagttacat tgaattatag aaacgatatc cgtaacgtcg
     1381 caattattgc ccacgttgac cacggaaaaa caacattagt tgatgaacta ttaaaacaat
     1441 cagatacatt agacgcacat acgcaattgc aagaacgtgc gatggactca aatgcgctag
     1501 aaaaagaacg tggtatcacg attttagcca aaaacacagc tgtagactat aaaggtattc
     1561 gcgtaaacat catggatact ccaggacacg cggacttcgg tggcgaagta gaacggatca
     1621 tgaaaatggt tgacggcgtt gtgttggtcg tagatgcgta tgaaggaaca atgcctcaaa
     1681 cacgttttgt attgaaaaaa gcactggaac aacatatcac accaatcgtt gtcgtaaaca
     1741 agattgacaa accttctgct cgtcctgagc atgtcgtaga tgaagttctt gaactattca
     1801 tcgaattagg agcagatgat gatcagttag actttcctgt gatttatgca tctgcactaa
     1861 atggtacgtc aagcttgtca gatgatccag cagatcaaga accaaccatg gcacctattt
     1921 ttgatacaat tattgaaaaa atccctgctc ctgtcgataa cagcgacgaa ccattacaat
     1981 tccaagtttc attacttgac tacaacgatt atgtaggtcg tatcggaatc ggacgtgtat
     2041 ttagaggaac aatcaaagta ggagaccaag tagcattaat taaattagac ggaacagtta
     2101 agaaattccg tgtaacgaaa ttatttggtt tctttggact aaaacgtcta gagattcaag
     2161 aagcaaaagc tggagacttg attgctgtct caggtatgga agatatcttt gtcggtgaaa
     2221 cagttactcc tgtggatcat caagatgcgt tacctatcct tcacattgac gaaccaacat
     2281 tgcaaatgac tttcttagtt aataattcac catttgccgg tcgagaaggt aaattcgtaa
     2341 ccgctcgtaa gattgaagaa cgtttgatgg cagaacttca aacagatgta tccttacgag
     2401 ttgaaccaac aaactctcca gatgcatgga cagtttctgg tcgtggagaa ttgcatttgt
     2461 ctatcttgat tgaaaacatg cgccgtgagg gatacgaatt gcaagtatct cgtccagaag
     2521 ttattgaaaa agaaatcgac ggtgtaaaat gcgaaccgtt tgaacgcgtg caaatcgata
     2581 caccagaaga atatatgggt agtgttatcg agtccttgag cttacgtaaa ggtgaaatgc
     2641 aagatatggt ccatacagga aacggacaaa tccgtttgac attcttaaca cctgcccgcg
     2701 gtttgattgg ttattcaact gaattccttt caatgacacg tggttacgga atcatgaacc
     2761 atacttttga ccaatatctg ccaatgcttc ctggtcaaat tggcggacgt caccaagggg
     2821 cgcttgtttc gatcgataca ggaaaagcaa cgacttattc tatcatgagt atcgaagaac
     2881 gcggtacagt cttcgtagaa ccaggtacag aagtatatga aggaatgatt atcggggaaa
     2941 acagccgtga taatgatttg actgtcaaca tcacgaaagc aaaacaaatg acaaacgtac
     3001 ggtctgctac taaagaccaa acatctgtca tcaaaaaacc aaaacaattg acgttggaag
     3061 aatctttgga attcttgaat gatgatgaat attgcgaagt aacaccagaa agcattcgct
     3121 tgagaaaaca aattttagag aaaaatgctc gtgaaaaagc atctaaaaag aaaaaataat
     3181 ctgtaaaagg atgaagagag aaaccagctt gttataaaaa atagctggtt tctttttttg
     3241 tccaactctt ttctgtggag aagtcatctt tgtcaatgga cataaattca gaaaatacgc
     3301 cgaaagacgt ttaaaagact tttaaaaaac ttatttctag agagtttttg tttcataata
     3361 agataatgtt tcacgaaagg agatcaactt gtccttcgaa gaaaatcgaa gtaaaatggc
     3421 aagagaaagg agcgggaaga tgaacgactt attaaaacaa tactttggct atgatgagtt
     3481 tagacctggt caaaaagaaa ttatccagaa agtcattgat caggaaaatg tattaggaat
     3541 catgcctacc ggaagtggga aatcaatctg ttaccagctt ccagctttac tattagatgg
     3601 gcttactgtg gttgtgtccc ctttaatctc tttgatgaag gatcaggtgg acgcggcgaa
     3661 tcaattaggt atacccgcca cttttatcaa tagctcgtta gatggttacg aaacagctag
     3721 acgcttccaa gaaatcgata gacagcagta ccgtttactt tatatcgctc ctgaacgttt
     3781 tatcatgccg gattttatcc aagcaatgaa gcgatggaac gtccgtatga tcgctattga
     3841 cgaggcacat tgtatctctc agtgggggca tgatttccgc ccaagttatt tacagatggc
     3901 gaaccagcta gatcaactgc caaatcgtcc tgtaattgtt gctttgacag ctacagcgac
     3961 tgtgcaagta gctgctgaca taaaaagact tttaaaaatt ccagaaaaca accatattca
     4021 gactggtttt gaacgagaaa atctacgatt tcaagtaatt aaagatcaaa aaaaagaaca
     4081 atatctaatc gaatatttaa agatcaacaa aaatcaatct ggtatcattt atgcagcaac
     4141 gagaaaagaa gtagaccgtc tctatcattt gcttaaaaaa ttcgattttt ccgtgggtag
     4201 atatcatggt ggtctaaatg agaatgagcg aacagaaatg caagaagcct ttttatacga
     4261 tcgcttgcag ctgattgtag cgacaaatgc atttggtatg ggtataaata aaagcaatgt
     4321 ccgttttgtt atccattatc aaattcctgg ctctctagaa gcatactatc aggaagctgg
     4381 tcgggcggga agagatggtc tttccagtga agccatcctg cttttctctc ctcaagatat
     4441 ccaagtccaa aagtttttta tccagcagtc ccaaagagaa gaagggcaaa agcaaaaaga
     4501 atatgaaaaa ttaaaagcga tgacagaata cgtgtatatt gagtcctgtc ttcagcaata
     4561 catcctaaac tattttggcg agacaagcag tccgtgcaac cgttgtggta actgtttaga
     4621 tgacagagaa atagtagaag taacgacaga agcacagatg gttctttctt gcttaaaacg
     4681 tatgggtgag aactatggta aacaaatgct gatgaaagtc ttagcaggat cgaaagaaca
     4741 aaagctgcaa gctttaggtt ttggacattt atctacctat ggactgatga aaaaccaatc
     4801 gcaaaaagaa acgatgcagt taattgaata tttgatatcg aatggctatc ttctgaccat
     4861 caatggtgag tatcctgttt tgaaagtaac agaaagaggg atacaagtat tgaaaggaca
     4921 agaatctgtt tatcgaaagg aacccaagaa agtccagcag ctatcggatg aagaaaccga
     4981 tacactattt gaagtgctgc gggaactgcg aacggatcta gcatcagaag caggcgttcc
     5041 cccgtatgtc gtattttcag attccacatt gaaagaaatg agccgaatac gtccatcaag
     5101 cagattggag atgcttcaga taaaaggagt tggccaaagc aagcttgata aatatggcga
     5161 agccttttta tctcggataa aaaatgcgga ctctaacgtt ctggataagt agaaagaacg
     5221 aatacgtaaa aatgaataaa aacaactggt taaatctgtt ttttttgctc cttatgaaaa
     5281 tcaaatatgt tataattaag gaattagaat gggaggtaag cacagatgga ttctttgtcg
     5341 aaaaaacttg cgatccaagt attaaatgat gaagcagaac ggatcaaacg attaatccga
     5401 aatcaaaaca acagtctctg tatctcacaa tgcaaagcct tcgaagaagt ggtagataca
     5461 cagatgtacg gcttttcccg gcaagtcggt tttgctgtcc gtataggagt aatcggaaag
     5521 aacgagggcc agctgatgtt aagtgagcta gaacgagaat tgaatcagtt atatagtgag
     5581 gtttaccaag aaatttatga taaaaaagaa gttggcaagg aggaatagac ttgcctaaga
     5641 aagtgaaaaa aaggcatcta ttagactata gcatcttgat tccctattta attttatgtg
     5701 tattgggatt gatcatggta tatagttcta cgtcgtatct attattagaa aacggacaaa
     5761 atccgtccgc atcagtcatt aaccagagta ttttttgggt gcttagcttg attgctatcg
     5821 cactacttta taaaatgaaa acagatgttt tgaaaaacca gcgtttgatc atggcagcca
     5881 tcgcagtttt gacgattttg ctgctgattg ttgtgttttt tggtaaggag atcaatgggg
     5941 cgaaaggttg gctgcaaatt gcaggattct cgatccaacc tgccgaatac ctaaaaatca
     6001 tttctatctg gtacctgtct ctgactttat ctaaaagaca aaacagtgta caaaaagatt
     6061 ttcttgggac tgtgaaacgt ccacttgcaa tggttatcgg acttactgca ttagtcgcta
     6121 ttcttcccga ttttggtaat gcggcagtta tctttttgat tattttggtt ctgcttttag
     6181 ccagcggagt caattatgtg tatactttga ttgtaggagt aggaggcttt tgtctaagta
     6241 cttttacgat ctggctgatc aatatcacaa acggaaagat cttacccgga cgtttacagt
     6301 atatctataa tcgatttgct atttaccaaa atcctttctc agacgaatta aataaagggc
     6361 atcaactagt caacggctac tatgccatgt tcaacggagg actatttggc aggggattag
     6421 gtaacagtat ccagaaaaaa ggatttttac aagaagcaca aaccgatttt atttatgcaa
     6481 tcgtagtgga agaactggga gtgattatgg ggattttgat attagcgttg ctattcttta
     6541 tgattgtgcg cattgtcctt gtaggtatcc gttcaaaaga tccgttcaat tcgcttttgt
     6601 gcattgggat cggcgcaatg tttttgatcc aagtatttgt caatcttgga ggaattactg
     6661 gcgttattcc tttgacaggg atcacgttcc catttttaag tcaaggaggc tccagtttgc
     6721 tgatgctttc gatttgtgtc ggctttgtcc tcaacatcag tgcggatgaa aaacgcaaga
     6781 gcttaggttt ataataaaaa aagatgtagg agtggttcga tgaaaaaagt tttagttgct
     6841 aacaggggtg aaatcgctgt acgtgtattt cgtgcttgta cagaattagg aattaaaact
     6901 gttggaatct atgcagaaga agatgaatat tccgtacacc gtttcaaagc ggatgaagca
     6961 tatttagtag gacaaggaaa aaaaccgatt gatgcgtatc tagatattga agggatcatt
     7021 tctatcgcga aagaatgcgg agctgacgct attcatccgg gttacggtct tttgtcggaa
     7081 aacttgaatt ttgcgcaacg gtgcgaagaa gaaggcatca tttttgttgg acccaaactg
     7141 catcatttag atatttttgg agataaaatc aaagcaaaag ctgcagctat cgaagcgggg
     7201 attgcttcga ttccaggcac agatggacca atcgcttcta tagacgatgc cttggagttt
     7261 gcgaaacaat acggttatcc gattatgatc aaggcagctc taggcggcgg cggacgcggc
     7321 atgcgtgtag ctcacgatga aaagagtgca agagagggct acgaacgtgc gaaaagcgaa
     7381 gcaaaagcag cctttggtag tgatgaagtg tatgttgaaa aatacatcgc taatcctaag
     7441 catatcgaag tacagattct cggggatacg catggaaacg tcatccatct ttttgaaaga
     7501 gattgttctg ttcagcgccg tcaccaaaaa gtagtagaag tagcgccttg tgtctctatg
     7561 aatgaacagc aacgtcaaaa aatctgccag gcagctgtcc aattgatgaa atatgtcggg
     7621 tatgtcaacg caggtacagt agaatttctt gttgaaggag atgattttta ctttatcgaa
     7681 gtcaaccctc gcgtccaagt ggaacatacg atcacagaaa tgattacaga tattgatatc
     7741 gtaacaacgc aactgttgat tgctcaaggt ttggatctgc ataaagaaat cggattgcct
     7801 cagcaagaag gaattaaatt aaatggttca gccattcaat gccgaatcac tacagaagac
     7861 ccgttgaata actttttacc agacacaggg aaaatcgata cgtatcgttc acctggtggt
     7921 tttggcgtac gtctggatgt cggaaatgct tacgcgggct atgtagtgac accgtatttt
     7981 gattcattgc tagtaaaagt atgtacgcat ggtgctacct ttgaaacagc cattcagaaa
     8041 atggaacgtt gcttgaaaga atttagaatc cgtggagtga aaacaaacat tccatttatg
     8101 ctcaatgtca tcacacatcc tgaattccaa tcaggaaatg caaaaacaac cttcattgat
     8161 agtacagcaa cattatttga atttcctcga ctacgagacc gcggaaacaa aacgatgaaa
     8221 tatatcggtg aaattactgt gaatggtttt ccaggtatcg aaagtggcga aaaaccattt
     8281 tatgaagaac cacgtatgcc taaagatcta atcacaagaa ctgattacgt aacggctaag
     8341 aatgtattag atgcgaaggg tgccgatgct ttggtcgaat ggatcaaagg acaggaaaat
     8401 ttgttgttga cggatacgac atttagagac gcccatcaaa gtctgctagc aactcgtgtt
     8461 cggacaaagg atttcaagca gattgcacgt ttgactggag aaggtcttcc tgaactcttt
     8521 tcaagtgaga tgtggggggg agcaacattt gatgtggctt accgcttttt gaatgaagat
     8581 ccttggcaac ggttgagaaa aattcgttct ttaatgccta atacgttgct gcaaatgctt
     8641 ttcagaggtt caaatgccgt tgggtattct aattatcctg acaatgtatt ggtggaattt
     8701 gtcaaagaag cagcagcgca aggaatcgat gtatttcgaa tctttgatag tttgaactgg
     8761 actccacaaa tggaaaaaag tatccaagct gtacgggata ctggtaaaat cgcagaggca
     8821 gctatttgct atactggcga tatcaacgat ccaagtcggg caaaatacaa tgttcagtat
     8881 tataaagaca tggcaaagga actagaacaa ctgggtgcgc atatcattgc aatcaaagat
     8941 atggctgggc tgcttaaacc gcaggcagct tatcgtttga ttagtgaatt gaaagaaacg
     9001 acagatctgc caatccatct gcatactcat gataccagcg ggaatggaat catcacttat
     9061 tctgctgctt caaaagcagg agtagacatc gttgacgtgg caatgagtgc aatgagtggg
     9121 aatactagtc agcctagcat gagcagcttg tattatgcac tggtcaatgg tccacggctg
     9181 ccagaaatca cgattgaaaa tgcacagaaa ttaaaccatt attgggaaga tgtgcgcatg
     9241 tattacaaac cgtttgaaaa cggcttgaat gctcctgaaa cagaagtata tatgcatgaa
     9301 atgccaggag gacagtattc gaatctacag caacaggcaa aagctgtcgg attaggtcat
     9361 cgctgggatg aaatcaaaca aatgtatcat actgtcaact tgatgtttgg cgatatcgtt
     9421 aaagtaactc catcatctaa agtagttgga gatatggcac tatttatggt ccaaaatgat
     9481 cttacagaag aagatattta tgaaaaaggc gaaacactaa gtttccctga atctgttgtg
     9541 actttcttcc aaggagaact agggcaaccc gttggcggat ttcctaaaaa attgcaaaag
     9601 attattctta aaggcagacc tgcattgaat gaacgtccag gtcttttggc tgaatcagtc
     9661 gacttcaacg aagtaaaaaa agaattggca gaaaaaattg gctatgaacc aaaacaagac
     9721 gaagtattaa gctatttgat gtatccgcaa gtctttttgg actatcaaaa agcatataat
     9781 caatttggcg atgttacatt actggacaca ccaacatttt tccaaggtat acgtttgggt
     9841 gaaacaatca atgtacaaat cgaacgcgga aaaacgctta tcattcgttt agatgaaatc
     9901 ggagaacccg atatcgaagg gaatcgcgta ctgttcttca atttgaatgg acaaagacgt
     9961 gaaatcacta tcaaagataa ttcgatcatc agtacggtcc aaacccgatt gaaagctgaa
    10021 ccgacaaacc gagaacaaat tggagcaacg atgtctggtt ctgttttgga tgtattagtg
    10081 aaaaaaggcg ataacgttaa aaaaggtgat acgttgatga ttactgaagc gatgaaaatg
    10141 gaaacggcca tcgaagcacg ttttgacgga gaagtcgcac atgtatatgt gtcttcagga
    10201 gacactattt cgtctggtga ccttttgatt gaagtgactg agaaataata agcgaaaggt
    10261 ggggaaacat gaaaagactg ggtttgtttt ggctgattct gctattagtt attgtggcat
    10321 tctacatgga accagtcttg tttccgccaa aacttgaagt gaaggaaaac tctgatcaac
    10381 aaatatcaaa ccaaatgaca acgtggaaat accaggagct taaagcaact ggtttttcta
    10441 cttatatcgg aaaaccgatc gatcagctgg aaaaggattt tggccaagcc tatgatcgat
    10501 taactagcgg atttggtttt gaaacaagat attatgaaaa taaagctagt catctcacat
    10561 ttgaagcgaa catccaagac agcagagtca caactgttaa agtactgcaa acagggcctg
    10621 ctgatatcgc gccgttttat ttagggatga cgatgcaaga tcttacgaaa atcactacta
    10681 tctatactaa tttcactttt gagtaccatg atacagaagt tggaatcgaa ctaatggaag
    10741 aggatatgaa ttatcgtccg ctaattgctt ttgataacga cacttttgct attttatttt
    10801 ttgatcaaac aacaaacggc ctattttcag ttgtgtattt agataaagat agtcttttga
    10861 aactattgcc atatcaagtg tttggtgaag gccttccaca ttatcaagca gataaatcgg
    10921 ctgattggga atcaatcaat cgcgttaaag aacgaaaaag tacgacttta ttaaatatgc
    10981 ttagaagaga agacgaactt cccatataca atcaaacact tgcctttcaa aaccacagtc
    11041 agctgctact acatgatttt ttgacaaggc ctgaggaaat attgtcagag gaacgtatgg
    11101 ctgattggca aaaatcgcta ggcagtgctc aaacgacagt gaaattctca ctgacgaatg
    11161 atgaattgga gaagttaatc agtaaacaaa aattagaaaa tactagtggg ctatttattc
    11221 atccggcgat tgacgctact ttttcgtttt tatattggta cagcgatcct tacaaccatg
    11281 accgtttcat ggacccggga acggattctg taggcattgc tttttctaaa gaaaatatgt
    11341 tagtcttatt gcaagaagaa aacggagaaa gtagtgatag cagtgatcgt taacgaagag
    11401 ctgtttcaac tggaggatca atgcctccaa gtcgctgaaa tgataaaaaa gagtaaaacg
    11461 atggcttctt atcttgaaca taaacagtca atggaagaat ctgcaaaagt ttgccagttg
    11521 aaagaagcgt tcttgtctaa gaaagaagca tttgaaaatg tagcggcata tggtgagtat
    11581 gcacctgatt atcgtgaaaa aaaacgagct gttcgaaaag caaaaagaca gcttgatatg
    11641 gatgagcatg ttgcagcttt ccgatatagt gaaacacagc tgcaaagtct gttggatcaa
    11701 attgtccaag tacttgccga agaagtttct aatgaaatca aagtagatgc aggtagcccg
    11761 ttttttgaaa cgaaaaaaca ctttggatgc ggaggtaatt gtcatgcaat tagacaatag
    11821 tgaatttgaa ataacaaaac gacgcgggct gatcgtatgg gtctacagct taaaacaatt
    11881 aaagaatctg aaaaagttcg gcttgttgca ttatgtctca agaagaatga aatatgtcgt
    11941 gctttactta aatgaagaga cattggaaga aacagaagaa cgaatccgta aattacattt
    12001 tgttcgaaac gtagaacgtt cttaccgacc ggatatcgaa atgaattttg ccgaaaaaat
    12061 aggaaacaaa acagtattaa aagacgaagg tttcgaaatt gaagagctaa atacagaaat
    12121 ccgattagct gaacatcttt aaaaatctct tatgagcagt ttttaaataa aaaataactt
    12181 ggataacgat cgatttttga tcattgtcca agtatttttt tggtatacta gtaccagtac
    12241 catttctaag gagtgagtag atgcggataa tatcaggaaa ttatggcggg cgccgtttaa
    12301 aaagtttagc aggggcgaac accagaccaa ctacagataa agtaaaagaa tccatattca
    12361 atatgattgg accatatttt gatggagaga cagtattgga tctgtttgca ggaagcggtg
    12421 gtttagctat cgaagcagta tctagaggct gcagtcatgc ggtatgcgta gacaaaaatt
    12481 accaagcgct aaaaatcatc aaagaaaaca tcgaaattac gaaagaacca gagaaattta
    12541 ccacaataaa acttgatgcg gacaaagcaa tcgaacggct agcagcggag aaacaacaat
    12601 tcgactactt gtttcttgat ccgccatatg caaaacaaaa aataatcgat caaatccata
    12661 aaatggaaga actgggactt ttttctaaaa ccgcagttat cgtatgcgaa acggataaaa
    12721 cagtcgaatt gccagaaact gtggctggat tccatcaaat aagaaaacag atttatggca
    12781 taacggccgt aactatctat agaaaagagg gaaatcaatg aaacgtgcat tattcccagg
    12841 aagttttgat ccttttacaa aaggtcactt agatacggtg gaacgtgcgg ctaaattatt
    12901 cgatgaggta gtaattggtg tttttatcaa tacttcaaag aaaagtttgt ttcccccaga
    12961 agaaagaatg acattgatca caaaagctgt ttctcatctt cctaatgtaa aagtcatgca
    13021 tcaagaaaat caattgacgg tagaaacagc aaaagagatt ggtgcagatg cgttgatcag
    13081 aggcatacga agtatcaaag actttgaata tgaacgagag attgctcaga tgaatcatca
    13141 tctatatgat gaattggaaa ctgtcttctt attagcaaaa ccagaatata gtcacgtgag
    13201 ttccagtatt ttaaaagaag tactgcactt tggcggagat gtgagcagct acttaccgcc
    13261 agtgatcaac gaagctttag ctggaaagcg tgaatcaaat gaaagctaaa caatggttga
    13321 aaacagtact gattatcata tttggaatgt tgatcattgg atttgtagta gttcccttgc
    13381 cgtattatgt agaatcaccg ggagccacga tcgatctgaa agaactaatt acggtcaatg
    13441 ataaggaaga taaaggttct gggtctttct ctcttacctc tgttggtatc aggcaagcta
    13501 caggtttctt agctttaaaa gctaaaatga ccccttttga agaattgatc agtgaagaag
    13561 aattgactgg tggggcgaca aatgaagaat ataatcaaat gcaacagtat tatatggatt
    13621 cttcccaaaa tgcagcaatc gaacaagcgt taaaacttgc agacaagcct tataaaatgg
    13681 aattcaaagg cgtatatgtc atgagtgtag agaaaacatc gaatttcttt ggcaagcttt
    13741 cagttggaga tacagtaaca aaagtagacg ggaaaagctt tcaaagtaca gaagcattta
    13801 tggattatgt aaaaagccaa aaagttggac aaacaatcga aatcagttat ttgcataatg
    13861 gtgaagaaaa aacagcttct ggtgatctga tcgagttacc aacagataaa aaggcaggaa
    13921 taggtatcac gcttactgac cataccgaga tcgaatcaga tacagatgtt cgtattaatt
    13981 ctggctctat cggtgggcca tcagcgggat tgatgttcac tttagaaatc tatgaacaag
    14041 tcactggtaa aaacttgcga catggtaagc aaattgcagg aactggaacg atcaacagtg
    14101 aaggagaagt tggccgaatc ggaggaatcg ataaaaaagt ggcaagtgcg gataaagctg
    14161 gcgtagagat tttctttgca ccagatgata cgatttcaga cgatgttaag aaagaatatc
    14221 ctgaaataaa aaccaactac gaagaagcaa aagctgccgc taaaaaattg aattcctcaa
    14281 tgaaaatcgt accagtaaaa acagtacaag aagcgcttga ctatctagag aaaatgaaat
    14341 gaaactaaat aattaaagag gggttgtgac acgagttctg tcacaacccc tctttttcgt
    14401 caaaaatctt cacgataaaa ataaaaacaa aagaaaaaat tgacgtaatt agatgttgaa
    14461 gggacgattt tgccagagct cactgtttct tcaattttaa atgaaaggag taatgaatga
    14521 tttttactgg tcattctttg aaaaaagaac aatgatagaa aaaatcagca agaaaatact
    14581 agcttcaccc aaattgatca tttggatgtc tatgatagtt cttatctttt gtatcgcaag
    14641 tggtttttta ttatcaaatt tgctatttta tagagaaaca gaagagactg ctgcaaaaga
    14701 aatactttct tcgtttagtt ccagtggaga agatccatca gctgaaggaa acgatgtaga
    14761 agaggatgct cgtccaaagg tcatgtacac cgatatcaaa ggaagtgtga aggagcctgg
    14821 tatctattcc ttttcttcag aagaacgggt ctatgatgta ctaaagcgtg caggtggatt
    14881 attagaagaa gcggatagcg atcgaatcaa cttttctgcg aagatagaag atcagcaagt
    14941 cctatatatc cctgctgtag gtgaagagct gccagaacat cttgatcagt tggcatcctc
    15001 ggaaggaaaa cagcctacag cagattccga gcctcccaaa ataaatatca atacagccac
    15061 tccatcagaa cttcagcaga ttcctgggat cggatcagtc aaagcgcaag aaatcattcg
    15121 atttagagaa gaaaacggat ccttccagaa agtggaagac ctgcaggaga tttctggtat
    15181 cggtgaaaag acagttgaaa aactaaaaaa cttcgttaca attaaataga atgattcaaa
    15241 atcgactggc acgagcaata aatggacgct aatggatact aagaataatc caattctaag
    15301 agcttggcag gacgaggagg tagtattttt ggataggaaa tagcttgatt gttcgcaaag
    15361 aaacattaaa aaaaccaatg ctgaatgtct atctccaaaa taaaatatct gggattcata
    15421 ttatgaatac ggctgtcagc ggcaataaca gtcaagctct acgagaacgc tttgccaaag
    15481 atgtacttag ctatacagca gataaagtat ttattctcat tgggacgaat gatctagcag
    15541 agcataaaca actttctaaa gaaacgtacc aaaaaatctg cagtggatga tagttcagct
    15601 gaaaaaagac tatagttctg atcatgcttt ctttatcacg ccaccagcag tcgatgagac
    15661 aaaacaaaaa tatcggaata acaagttgat caaagaatat atctctgttc tcacagaagt
    15721 agcaaaacgc catgattgtg aagtatcgat ttttatacgg aatttcttga acaaatggat
    15781 tcgaagaatt tttataatgg gctaatggat gacggacttc atttcggcag tgaagggtag
    15841 gatcttttgt cagacaggat gattcgttat atttaaagaa tattttgttt aagcaatgag
    15901 tactttttaa tcaacttgaa aaaacggagg aatataaaac atgttagaaa aatcttcaaa
    15961 agcatgcgat acgaataaag aaaaagttac tgataagtca cataatgaac gcattccttg
    16021 ggaccagtac tttatggctc aggcagtact gttatcttta cgtagtacgt gtacacgttt
    16081 agaagtagga gcgacactcg ttcgagaaaa aaggatcatt gctggcggct ataatggagc
    16141 agtcagtgga gatgtccact gcatagatga agggtgttac gtcgtggatg gacactgctt
    16201 gcgaacgatc catgcagaga tgaatgcact cctacagtgt gcaaaacttg gtatcccgac
    16261 ggaaggttca gaaatctatg tcacacattt tccatgtttg gcctgtacaa aggctttgtt
    16321 gcaagctggt gtgaaaggga tcaattatct ccatgactat cgaaatgatc cttatgccca
    16381 agcgttgatc gaacaattag gtgtatctgt acaccaagtt gctttagact cacagcattt
    16441 ttcaaaactt caaaatgaat taacaggaaa acatgtctag cgttttagaa aggcatgttc
    16501 gaaatcggtt gatttttccg gcaattacgt cgatgattat ctgtttgttg tattacactg
    16561 acaattgggg ttatcgtttg cttcttgccg gaattttttt atggttttcg ctaaaagaag
    16621 gacgttttat cgcgtacttg tgtattttgt gtagcataac ggtatccatt tcttataggc
    16681 tacaagagta ttcattttta gaggaaaaaa caacatctgc gcaaattact gtatttacag
    16741 atacgattcg tgcaaatggt aattttttga caatggaagg aaggttatca gagaataaac
    16801 aaaagctcca gctttcttat caagtaaaca cagaagcaga attgaaaaca tggcttaact
    16861 tccgaggaaa gggaatagaa ttgactgctg aaggcgagtt catctctcca gcaaaaaagc
    16921 ggaatcttta taattttgac caagaagctt acttcaggaa ccatagaatt tctggacggt
    16981 tccaaattca aaagattgaa cagatcacca tgcaaaatca ctggcgaaac tggcttcaga
    17041 gaaaaagagg atcttttatc tcctttgtcc aatctgaatt tccgcaaaaa acaagtgtat
    17101 atattaattc tttattatgg ggctataaag atgcaggatt cagagaacca gaagaaattt
    17161 ttagggagag tggtttgctg catctgttca gtctatcggg tctacacatc caattttatt
    17221 tagggtggct gtattattta tttcgacgta tcggatggcc actacacgtc agtattattc
    17281 cgttgagtct actaactatc tgttatgttt ctattgcagg aagttctatt tctgttttgc
    17341 gtgctagttt gctgttttta ttgcgattgc tagtcaaatt gctgaataag cattattcca
    17401 ccatggactt atttgcagtt gtcttttggc ttcttttact atttgatcct cgatttcttt
    17461 ttcatgcggg tggacagctt agttttttca tgagtttttt gtttatcctg atttcttttg
    17521 atggagattg gttgaaaaaa acggcctctc acgtcctgtt tactatgatc acgatgccgt
    17581 tgattgtatg gcatttttat gagtggccta ttttaggtag tctttttaca ttactgattg
    17641 caccggtatt caagtttctt tttcttcctg gtgtgttatt tctcacactc ttcaatcgct
    17701 ggctgccgga aactttactt ttgctgatag aagagggatt aatcttattt gagcgaataa
    17761 tcgatttttc ttcagggtcg tctctcatta taggacgttt gccccttgtg ctatctggga
    17821 tgtatatttt cggattactg atttgtatgg ataggttgaa agaacaacct gtgaaacact
    17881 tgttttatgt tggtcttttt tcttttattt ttttgacttt gccattttta cgcttttctt
    17941 caacgatcgc ttttatcgat gtcggtcaag gagacagtat ctttttgcaa agtccttttc
    18001 gaaaagaaac gattttgatc gatactggag gtcagttaca ctttgaaaga gaaaagtggg
    18061 cgcaaggtat gatacgtcct cctgctgaaa gaaatatcgt tccatatcta aaaggtcagg
    18121 ggataagtgt aatcgataaa ctcatcttga cacacgacga tacggatcat gtgggagaat
    18181 tacccacgtt atctcagcat tttactatca aaaaaattta tatcggttgg ggcgctggac
    18241 gaaatgagcc attacaaagg catttatctg aagctcaaaa aaatggtact gagatcattg
    18301 aaatcaaaca tggggacagg atcagcggtt attatgatct ttatgtattg actccttttg
    18361 aaaagggaga gggaagaaat gaagattcga ttggtctatg gatggaatat aacaataggc
    18421 gctttttatt tttaggagat ttgaatcaag caatggaaaa acaattgctt ttgatttatc
    18481 ctaatctgaa agccgatgta gtcaaattag gtcatcacgg tagccgtacg tcaagtaaca
    18541 cagattttct ttcccatatt gaagcaaaac atgggattat atcctgcggc gtaaataatc
    18601 gttatggtca cccgcacagc gaagtattgg agacactaga agaaaatcag ataaaaacat
    18661 ggcgaacgga tcaacaagga atgatcacct atcgctggca tccagttttt catcctcatg
    18721 ggctagtgga aacaatgata gactagtaat tctcatctgc tcatggtagg ataatttttg
    18781 aaagtggtga gtaatttgag tatacaagca gagttacaaa aaatacgtaa agaaaaactt
    18841 gcatcttgtt acttgatttt aggaacagaa aagtttctcc aagatcaagt tcggacagaa
    18901 attgtcaaaa aaatccaatt agagggcgaa gatgacttaa attttttaag ttttgacatg
    18961 gaaaatgcaa gtttagatga ggtagtagct gaagcagaga cgttgccgtt tttcggagat
    19021 caacggttag tattcgtaga gaatccttat tttttaacag gtgaaaaagt aaacaatgga
    19081 atcgaacaaa atactgattt attgacggct tatttgaaag aaccattaga atcgactgta
    19141 ttagtattct ttgcgccata tgaaaagttg gatgaacgga aaaaagtaac gaaacaattg
    19201 aaaaaaacag caattatcat caatgtccaa cagttgaatg aaaaagaagt acgtcaatat
    19261 ctgatgaata ccttagagaa ttcctcaatc aaaatggaac gaagtgcaat tgatttattc
    19321 ttgaggttga ccgacttaga tttatccaaa atgatgagag agttacagaa attggtcctt
    19381 tatggacaaa atcaacagca aatcacggta agagaagtag aagaattagt tcctaaaacg
    19441 ttagaacata atatttttga catgacccaa tatattttaa aagggaagac ggaacaagct
    19501 ttgcgtttat acgaagattt agttatgcaa ggggaagaaa caatcaaaat taatgcgatt
    19561 ttgctttctc aattacgttt atttttacag acaaaatttc ttgtaaagat tggttatcag
    19621 caggcaaata ttgctgaaac attgaaaatc catccatatc gtgtaaaact tgccatgcag
    19681 gaagtaaaaa aattcgatga acatttgctg gtacagttgt ttgatcaatt agttgagatg
    19741 gattatcaaa tcaaaacggg acaaatcgaa aaagaattaa gttttcaact attcgttttg
    19801 cgcacagggc agttgttaag aaatcgataa gaagaaagac gagggcaaag catgcgggaa
    19861 ggtcgtttgt ttttgtcctt tttttgacaa ataaaaaaat cggccgaagc cgattctttt
    19921 atttagcgat ttttttgctt aaacgagatt tgtcgcggtt agctttgttt ttgtggatta
    19981 gaccttttga ttcagccata tcaatagctt taacagcttc tttatataac gcatctacgt
    20041 tgtcagcacc tgaagctaca gcatcttcaa attttttgat tgcagtacgc atagcgcttg
    20101 tttgagatga atttttcaca ttagcgtttt cgcttgtacg aacacgtttg attgcagatt
    20161 caatgtttgg cattagtttc acctccgata acttaagttc ttacgcgtgt taccgcataa
    20221 ttcaacattc attattatac ctaaaggcag cgtgctttgc aatatgaaca tgacaagttt
    20281 ttttccttaa cagtctttta ttaggatttt ttttcagtaa aaacggatag tacaagctga
    20341 aaaaaatcaa aaagacgcta ttgtgggagg caatagcgtc aaaccaaact agatttttat
    20401 ttatctattt aaacaaagtt tgaatgggaa tgtttggtac taagttatta tataacaaag
    20461 agaaccgttt gcaaagtttt ttttgaaaag ggatacgatt ccctgttgtt ctttgttttt
    20521 ctattaagaa actgcagtta ttttataacc agtatccttt gatcagtaaa ggctattctg
    20581 gtgtaccgat tattttaatg tattcatcga tattttttat caacattttt tttatgacca
    20641 actggttccg acggttccat ttgccactta cttccagcac atatttattt aggggcaaac
    20701 gtaagatata ttttgccaaa tagcgatctt taagcaggcc attgatcaca cggtcctcaa
    20761 gctgcaagtt gatcccagtc agcatcattg gctgttcttg taaaacgtac gtatcaatta
    20821 aaagaccttc aaaagtttcc acaagcgtct tcctttcttt tcaaagtaac ctgaaaacag
    20881 gcactaattc ttccattttg atattcgttg aagtggatgc gatcattctt tcttttgtcc
    20941 actgtaatct agtataacaa aaaagagcag aagagccaaa aagaaaaaag agcatcgaat
    21001 tctataggaa gtctcattgg cacggcctaa attattacaa aacattgatt aaaaaaagcc
    21061 cctgcatcgc aggagcatcc cctatatcgt tttaataggt caatcaaaaa gcagtatcaa
    21121 acacattttg tatcaaatca ggaaataata gataagctaa gcccagaatc aaaagtaccg
    21181 ctagaagaaa ccagccgatt gttcctatga aatactttaa tttttcgaac attgtatcac
    21241 ctcgttgtca gtatatcacg gatcagtaaa ttgggggtgt taagaatctc ctaaaataga
    21301 caaaatttgt tctattttcc taaagcaaat acttgtaaga tacagtaagt gataccagaa
    21361 gcaatgaccg gtccggcggc gattcctctt aagaagacaa cacctaaaat cgtgccgaaa
    21421 acaagtgcaa cagtgatttg tggatcagaa gcaatcaatc ctacaccctt ggaagataag
    21481 acagccacta gcccaccgca aaaaacagct acccagccaa taggggattt aaaggcttct
    21541 aatagatcac gtagaccgat ttctcctgtt gcgataggga ttagaatagc cgctgtgatg
    21601 atcgtcaccc caatattgat tcctttgcct tgaagccaag ggaaaaagga acgggaggct
    21661 ggtatgagct tcataatcaa aacaaaagct gccgctatca tcagactttg atttttagct
    21721 aaaattgcta caagtaaaat aattcctaaa aaaagccaac tttccatgaa atatattcct
    21781 cactttcttc gaaacaatca taacatgttt ttagaaagtt acaaaagtag gaattcatcc
    21841 ttcaagacct attcataagc tgtttttttc ataaaataaa caaaatcata aaaaaacact
    21901 ttgcttattt gacagaagac agccgcgctt tgtatagtgg acaagactta catttttttg
    21961 aagaatcaga aagatcaggt aaaggtctta gtaaacgcaa gccattcaga ataaccaata
    22021 ttgtgcttcc ttcgtgtcct acaactccaa gaggtagatt taaaaattgc aggaagttag
    22081 aagcaatcaa caagagaata acaagaatcg aaaaaataat attttgtttg atgatccgcc
    22141 gcatttttaa agatagccga tgactgtaga caaatttatt taagtcgctt ttcattaaga
    22201 cgatgtctgc gatatccata gcggcatctg tcccttgccc catagcgaca cctaaagaag
    22261 cggctgctaa agcaggcgca tcattgactc catcaccaac catcgcattt acttggtaaa
    22321 gttcattctc ttttttgact agttgtgttt tttcttccgg agtacagctt gcatagtaat
    22381 gttcaatccc tacttgttca gcaatggcct ttgctgtgcc agaatggtcg ccggttatca
    22441 tacttgtatg gatgttttgg gatttaaagt aggaaattac ttgttgggta tttgcttttg
    22501 gaatatctag cagacctaaa acagcaatta actgctgatc tttagaaaga taaatcacgg
    22561 ttttgccttg attttccaaa cgttcgatca tttccgcaat ctctttgctg attatcatcg
    22621 tctcaggatc atatgcgtgc ttgccaactt tccattgcgc acctaaatag gtagtttgta
    22681 atccaaaacc agtaatttct tctattggta agtattggat ttcttcaggt attgtgcaat
    22741 cgaaatattg caaaatcgca tgagcaagtg gatgcgtcgt tttttgttcc atagcaacaa
    22801 gaagttgttg tgccaaatcc ttttcatcaa agaaaaagct gtcagttaca actggttttc
    22861 ctttagtgag cgttcctgtt ttatcaaagg caatcgcttt taattcagaa agcttttcta
    22921 aatggatacc gcctttgatt aaaatcccat tttttgcaga atttgaaaga gcagctagag
    22981 aagctggtgt agcagatgcg acaagcgcac aaggagaagc cacaactaat aataccattc
    23041 ctcgataaaa gctttcatcc caactccaac ctaggaaaaa gtgggggaga aggatcatta
    23101 gaggaacagc aagcaaaatc aattttacat aattattttc gattcgttcg ataaatgaag
    23161 ctgtttgagt tggcgtattc tgcgcttctt ctactaattg gataatctta gcaaagacag
    23221 tttcggaact cgtttttgtt actcgaatcg tgatgggatt tccttgattc agcgttcctg
    23281 catacatctc atcgcctaaa tatttttcta caggcacaga ttcaccgctt aatgcagact
    23341 catcgatcgt tgcctgtgtg ctttctaaaa agccatctat cggaacagct gctcctttag
    23401 cgacaaatac caagttatcc acctttagtt gagaaacatc tacttcttgc atttgtccat
    23461 tttcttttaa taattgggct ttttgtggtt gaagattcat caaagcagta atttcttttt
    23521 gacttttatt agttgtgtat tcctctaatg caccgcttaa acaaaagatg aatgtcaaca
    23581 ttgctccttc aaagtaatta ccgatcaaac aggcaccaat agcagctaaa gccatcaata
    23641 aatccacatt cagtgtccga tcattccaca attctttcaa gccttccgat gtttgtttat
    23701 atccaccgat gataatggca ctgatataaa aaagtggggt gatggtaaga gagaatcggt
    23761 cgaagataaa accgaagatc ataaataaaa ggcagccgat tgttgctgca aaagcttttt
    23821 tctgattagt catcgttatt agacctcctt gtcaaaacaa ggatagcata ataaaaatgt
    23881 aattgataat aataacagct aaatgagaac gataatggtt atcatttggt gattaagctt
    23941 gatgttgttt ttattattta taatgattat tattaaagaa aataaaaaac cagaacattt
    24001 ctcaaataag agaagtgttc tggttttttc tacattgcaa taaaccaata accaatcaaa
    24061 atgataccaa ggataatacg ataccagcca aaagcggtaa agtcgttttt cttcaaatag
    24121 cttagtaaga atttgatagc taagacggaa accacaaaag atacgaatgt tcctacaaga
    24181 agaacaacag tttcttccat tttgaatgaa ttcccttcag ctaaatattt gacgatcttc
    24241 aagccgcttg cgccaaacat gacaggaatc cctaagaaaa atgaaaactc tgtagcgaca
    24301 aaacgcgaag caccaatcaa gatagatcct aggatcgttg cgccagaacg ggatgttccg
    24361 ggaacaagtg ccaagacttg gaataaccca acaagaagag ctgcttggta cgtaaagtca
    24421 ttcagagaag tccaacgagg tgttttgttt ttgttgcgtt tttcgacaat aataaaggca
    24481 ataccgtaaa cgatcaaaac aatggcaact ggtaagaact tgtggaaatt tgcttctaac
    24541 caatcatcca aaggcaaacc aatgatgatg gctggtatgc aagcaacgat cactttaaac
    24601 caaagtgtcc acgtatcttt tttttctacc gttgatttac ttggagaaaa tgggtttaac
    24661 ttgtgaaaat aaagaacgac gacagccaag atcgccccta attggataac gacattgaac
    24721 atcgacataa attgtgaact ggcatccagt ttgatgaatt catctgctag gatcaaatga
    24781 ccagtactac tgatgggcag ccattccgtt attccttcaa taataccgag aatcactgct
    24841 ttgataatat ttgcaaaaaa cataaattcc ttccttccca attaagatac atcttatagt
    24901 ataccgttat tttttgagaa acccaatctg ttttttaata ttaagaaaaa cttgagaaat
    24961 aaagcagata agtacacgaa gagaaaaaag aagacaaagc cctcgttcag actttgcctt
    25021 ttatgattct ctggtaaaaa ttaaaatatc cccattatag aaacgagtcg cgactatgtg
    25081 ttttcccgtt atcgatataa gacgtatcat tgatgccgtg gatagaaaat cgaccgtttg
    25141 cataagtgac ctttgttacg ctgccattta aaagcccagc acgaacaggc tgtttaggat
    25201 cgatcagatt aagcaaaaag gcgatcgtca aaccatgaga tacgactaaa acatttccac
    25261 caccattttt ttcgcagtga tgggcgatat cttcaaatcc tgtccataca cggtctcgca
    25321 atgtttcata agtttccgcc cacccagcgg tatctaagtt gtatacagca ttagcaattt
    25381 gttcaaaaga aacttctgtg gtaaacattt catcatatgt tttaaaattc aatacacgag
    25441 ggatcacacc ccacatttcc atgtcatatc caccttcaag agacccgaaa caccattctc
    25501 taatcctttt ttcaataaaa taaggaattt cttttccctt agaatgttct cctagaataa
    25561 tacgggcagt ttcgattgca cgaccactgt cactagaata agcaaatgaa aagtcgacat
    25621 tttttaaccc gcgacctaaa taatgaatgc cttcttgtcc ttgctttgtg aggggtgtat
    25681 cacaccagcc ttgtactcgt tcaattgtat tgaacatcgt ttttccgtgt cgtacgatat
    25741 aaagtgtagt ttctgtcatt ttattctcct cctaagtcgt tttaacgatt gaaaaaagga
    25801 tttgtccttt tttcctgttc aatcgtcgtt gcatcgccat gtcctggata gactgcaaat
    25861 tcatcaggta atacaaacag ctgggtccga atactatgaa gtaattgttc taaattccct
    25921 gtatacagat cggttctacc gatacttcct ctaaacaggg cgtcgccaga aacgacaaaa
    25981 tcatcaaaaa taaagctgac gcttcctata gaatgccctg gggtagggac gacgcgaaaa
    26041 gacatgtttc ctaaagtata agttttcatt tcaaattcat attctgcagg cgagacaata
    26101 acatcagcaa tatcatcatg tctaccgagt ccagaaagat tcaaaatcgg atcacctagc
    26161 catttttgct ctagtgggct gacataaact gggatttgat aatacgcgcg taaaggttcc
    26221 actgcaccga tatgatcgta gtgagtatgg gtaagcaaaa tcgctaccgg ctgttggttt
    26281 gtttttttga tttcttgttt gattcgttcc gcatcttctc cagggtcaat gatcaaaagt
    26341 gcttcttcgt tgtagaccaa ataacagttt tcttcaatca ttcctgtttt taatctttcg
    26401 atatgcatgt gcattcctcc ttgatagcca aaacttcttt catccattag tataacgcat
    26461 tcattgctag gaaacaaaaa caggtactta tttctcttta cttatctgaa ttatcagact
    26521 atatgaaaag tatttggata ttctaaagag aaggaaagta agttttcata gcattttaat
    26581 atgtccttgt tacattagat tcatccaaaa atccaaattc tatatcctat atccctgcct
    26641 aatcagcagg gtgttttttt atgtttggaa agagagctct ttttgctaaa ctaggttttt
    26701 tcaggtaatc ttagagagaa agaggtggtg gaaatgatca aacagtcaaa aatatctgtg
    26761 cggcacttag tagaatttat tttgcgacgt ggaagtatcg acaatcgtaa aaaaagtaac
    26821 catactgcat tagaaggagc gagaatccac cgcaagctcc aaaaagatgc gggagaaaac
    26881 tatgaaaaag aagtcttttt aaaaacaaca gttcaattag atgaatatta cctgatcgtt
    26941 gaaggccgtg cagacggtat tttcaaaaga gacggtattt attatataga tgaaatcaaa
    27001 acctccgaac cacgatttga agatttagaa ccagaacaag tggaactttt ctttcatcaa
    27061 gcaagggtgt atgcctatat ctatagtcaa gaacatgatt tacaagaaat aaatctgcaa
    27121 ttgacttact tccagacggc agaagaagtg atcacgagaa aggttgaaca tcagacaaga
    27181 gagcagttag aaactttttt taaaaagctg actgaagatt ataaagaatg gcttgttttt
    27241 caagaaaact ggcgcactgt acgcaatgcc tctttgatgg ctttgaaatt cccccatgat
    27301 gagtatagga aaggtcagcg tgaactagcg gtagctgctt ataaaacgat ccgtacgaaa
    27361 cagaaattgt ttgtagaagc acctaccgga acaggaaaaa caatctctac gttattcccc
    27421 gctttgaaag ctgtagggga agaagaggga gaaaagatct tttatctaac ggctaaaaca
    27481 ataactagac aagtagctga agatgctatg acagcattaa aagatacagg agctgaagta
    27541 aaaagtgtca ctttgacggc gaaagacaag atctgctttt tagatgagac gacctgtaat
    27601 ccagatcagt gcccatatgc caatggttat tacaatcgga ttaatgaagg tttatgggat
    27661 cttttgaatc atgagaatca gatcactcgt gaagtcatcg aaacttatgc aagaaagcat
    27721 acactttgtc ctttcgaact atcattagat gtcagtatct ggtgtgacgt aatcattggg
    27781 gattacaatt atttatttga tccaactgtt tatttaagac gtttttttga agatgaaaaa
    27841 aacgaggact atctgttttt gattgacgaa gcacataatt tggtgaatcg ttcccgagag
    27901 atgtattcgg cagaactatc ttatgaaaaa acgaaacgaa gtaaggaagc tataccaaag
    27961 gaattcaaaa aacttcatcg ccgtttcaac aaactattaa aagaatttga ttcgatccga
    28021 gaaatagcaa aagaagatca ttgggattat catcatcaaa aagcaccggc tgaatcttta
    28081 gtaaaggcag gttatcaatt aagcgaaaaa attaaagaat ggctggcaga atttcctgag
    28141 cacccatcac aagaacaatt gcttccttat tattttgatt tgcttcattt tttgaaggtc
    28201 agtgaatttt atgatgatca ctacgaaaca acagtcgaaa aaacgtatcg cgatctgata
    28261 gtaaaagagt tttgtattga tccaagcttg tttcttgagc agtcgttgga taaaggaaaa
    28321 agcagtattc ttttttctgc tagtttttca ccactctctt attatcagga aacactgggg
    28381 ggacaaaaaa gtctggctta caaactgccg agtcctttcc cagaaggaaa ccagcaagtt
    28441 ttcatcgcaa attacctaga gacgacttat cgaaaaaggg aacacagtct ggcaaaatta
    28501 gtagagacga ttcatgcttt tgctgatgga aaggtcggga attatttcgt tttctttcct
    28561 tcttatcaat atttagatct tgcggtggaa gcattcagac agcaatatcc cgacagcaat
    28621 gtgctaatcc aagaaacgga catgaatgag gaagaacgcg aacgattttt aacaaaattt
    28681 caaacaaatc ccgctgaaac attgattgga ttttgcgtac ttggcgggat tttttcagaa
    28741 ggaatcgatt tgagagggga ccgattgatc ggcagtatga tcgtaggtgt aggtttgccg
    28801 cagatgaatc atgagcagga actgatcaaa tcatattatg atgagaagga acaccttgga
    28861 tttgcttacg cttatcagct tcctggaatg aacaaagtct tgcaagctgg tggtcgagtg
    28921 attcgtggca tggcggatca aggaatcgtt gtattggcag atcaacgatt ttctagtttt
    28981 tcttatcgac gtttattccc acaacattgg caaacagcaa gagaagtacg aagtgttggg
    29041 gaattggaag aaggaataca gcgtttttgg ttatcaaaag aagcagtaaa tcaaaaaaac
    29101 gaggaatgac agacgtcagc ctcgtttttt gattaacgat agttagtgaa ttgcaactcg
    29161 attggtaagt caagtttacg taataaagca atcacagctt gtagatcatc acggttctta
    29221 cctgtcactc taatctgatc ttcttggatt tgtgctttta ctttcagttt ttcatttttg
    29281 atagctgtag tgattttctt cgcgttttca cgatcgattc cgttgaccaa atcggcagtt
    29341 tgtcgagctt tgccacctag agcgtgttct gattcggaaa aatggatatt tttgattggc
    29401 acatttcttt tgatcagctt accaaataat acatctttga tctgttcgat tttgaaatca
    29461 tcatcgctca atacaactag attgctgttc tctaatttga tttctactgt agaatccttg
    29521 aagtcaaagc gattggacaa ttcttttgtt gtttgctgaa tcgcattttt tacttcttct
    29581 gtattgactt ctgatacaat gtcgaagcta gcatcttttg ccataggaac cctcctgata
    29641 tacatataaa tatttaccat acatctatct tatcatagga ttagggcaga ttcttacctg
    29701 tttgctaaaa ttcttctcat ttgagttcga agtattttat tttaatagat aaactgttat
    29761 tcttacattt ggaataccaa agtaggggag aggtgcttgt gagtaaaatt atgactgcgt
    29821 atcataaaaa tgaaagatta aagaaaatag tggttatttt gataaccgga ttgaccgctg
    29881 cggtcgcttt aaattatttt ttgattccag ccaatgtctt ttctgcaggg atgaatggga
    29941 tcgctcaaat catttcctcg cttttatatg aatggtttca tatcaagata gacacaggaa
    30001 catttatttt tcttttgaat atccctgtgt ttgtattagg gtttctcaaa gtaggaaaac
    30061 gagcaacgat ccttagtttt gtgaatgttg tatgtgtatc ggtgatgacg atgctgcttc
    30121 cagtcggaca gatcactgat aatattttga tgaatgccct agtaggcggt gttttattag
    30181 gtcttggcgt aggattatct ttaaaaatgg gctttacaac tggtgggatg gatatcatct
    30241 ctcttgtact ttcacaaaca actggaaaaa cagtcggaaa ctacatgctg attctaaatg
    30301 gtatcattgt agtcatcgca ggcttcttct ttaactggga aagtgccttg tatacgatta
    30361 tttccattta tgcaatgact caagtaattg atgccatcca cacgagtcat caaaaagtaa
    30421 cagcaatgat cgttaccgtc aagccagaag aggtaacaga agaactagca aaacggatgg
    30481 tacgtggaat gacattactg ccgtctgtcg gtggctattc aaaaaaacaa gggaacatga
    30541 tcatgatggt catcacccgc tacgaaatgt atgatcttga tcagatcgtt catgaaatcg
    30601 acgacgatgc atttatcaat attttaccaa ctcattcagt atttggccgg tttgcaaatg
    30661 aaaacgaaca aaaaatgtat cgaacaactg gcgtattgcc agaaataaaa aatcgttcac
    30721 aaaaaaaatg aggaatcagg tttattttag aataaattta atctattaca tctaataaga
    30781 acatttttat aaatttaaac gagaatctta cttctaaatt ctcatttaca agcagctaaa
    30841 aaaagagtat gataaataaa aatcgtgtta aggagtgtcg tacgatgagc gaagcaaacc
    30901 aagaacggtc tggacaagaa atagaactaa tcaaagaacg tattcttgct gccttggaaa
    30961 tggtgattga tcctgaatta ggaatcgaca tcgtcaattt aggcttgatt tatgatatag
    31021 aattcaatcc tgaaaatgga gaaacagtca ttaagatgac tctaacaact atgggctgtc
    31081 cattagcaga tattttaaca gaatctatcc atgacgcatt aaaagaagtg ccagaagtaa
    31141 cgaaagcaga agtcaaacta gtctggtatc cagcatggac gacagataag atgagccgtt
    31201 atgcacggat tgcgttgggg atacgataga aatcttggct gactagctat gagaagcaaa
    31261 taggaaaaac aaaaaagcct tttatccttt ctagaagaaa agagataaaa ggtttctttg
    31321 tttataaaat tttgtctgct atattataag ttaattaaat aaatgtgttc tattgataaa
    31381 ggacattcaa atccctttcc ttttggaatc cttctttttt acatcagttt gattttcgta
    31441 tagtattctt tctcatcttc acgataaatc gcagccccat ttttttgttg tgctttaaga
    31501 ctgccaagat tttttttatt tacagacaaa agtgcctcat caatgccgat tttttttgcc
    31561 tcttgtagta ctaatgctaa tccttgtgtg gcatatcctt ttttacgata attaggggag
    31621 atgccgtaac caatatggcc agcgccgttt cttaatgttt cgttcagttt atggcgcaaa
    31681 ttaaaaattc ctacatactc atgttcatca ctttctaaaa taaagacggt tgcgggaacg
    31741 taactctcag gaagatcgat tcctaaagac gttttttcgc atttttttac ataatctaaa
    31801 aattcagcaa atgtatagcc ataagcattg ttgataaatc cactctcatt tggtccaaag
    31861 ctagtttgta gctgataagc tttctttaaa tctgcttccc atagtttgat cagtttcatc
    31921 gtattcacct ctttaagtaa ccttattcat ttgttttcta ctatagcact attgttgtaa
    31981 atagccatgc ctatttttat ttattgtgtc atatcgtatt aagaatcatc gaacaataca
    32041 aatatgaatt acaataaaaa aattatttga agttcgttca ttcgttactt atgatctcta
    32101 gaagaaagaa aacgtgaatt acttcagcgt ctagaattcc agaaggatag taatcaacag
    32161 aagaaataat caatatccaa atgaaagaag atagctgaat cgagaaaaag aggaaaaaag
    32221 aaatgaagaa aaaaataaaa tagttactaa tcccagagtc gttcgtttaa cattgaaatc
    32281 gatcatatgg ataaaacaga ttttttcacc aaccctcaat agatgatgga gttgctcgga
    32341 tgaattattt gtgtagatgg cataagggag ggcgtacaga aatgaaaaag aacaaaaata
    32401 tgttcttgac aaaaaacaca tgtaatccta aactaaaaga tgtgatgcgg ctatggcgga
    32461 attggcagac gcgctagctt caggcgctag tgagggtgac ctcgtggaag ttcgagtctt
    32521 cttagccgca taatttgttt ttttataaag agaaggtaca cctggagcga tgagaaagaa
    32581 aataacatat tatctaaaag aatataggaa aaattttaaa caacggaacc agattcaaat
    32641 aaatcaaaaa aaatttgtgt gaaggtggga cagtttaaaa cctaatagat tgattcaaat
    32701 agtagattta tagattctga tacaagaaat actggcaaac gatagttaag gaataaagac
    32761 taaacttaaa ctcaaaaaga ggtcatgcga aagaataaat cgcatgacct cttactatat
    32821 tttgaatgtg tttaaacgtt caaataatga atcttagtac caaccgtttg cttcccagaa
    32881 tgctttcgcc gcttcccaag aaccataacg tgaagtaaca tattgttctg ctactctttc
    32941 ttggtttgca gcagagtagt caccatttaa gtaagaagaa tctaattggt aacggccgat
    33001 gtaacgtccg ttcgttgctg tgtaagaacc gcttgattct ttttgtgcga tccattcttt
    33061 tgcagagctt gtacttgctg gagtagcagc agtttctgtt acagcaggag caggttgtgt
    33121 ttcagcaaca ggcgctgctt gtgtttccgt ttgaaccgtt tcttgtacaa caggttgttc
    33181 agcttgaaca ggttcagctt ggactggtgc ttcttgaacg gctgcttgag gttcagcagc
    33241 tgcttgtgca gagccttctg ttgggattgt taattgttgt cctgagtaga tcaggttaat
    33301 atcagaaatt gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt
    33361 ttgagaaatc gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc
    33421 agtcgttccc atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt
    33481 aagtgatgtc atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg
    33541 aggaatactt taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca
    33601 aatccacgtt ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc
    33661 acataatgca gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa
    33721 taacttgaaa gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt
    33781 atttttgctt gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata
    33841 ccagaacatc atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc
    33901 ccttgactta gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt
    33961 tgagctgacc catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac
    34021 agaagtagcc atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca
    34081 cgcaatagtt gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga
    34141 aaatattgat ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt
    34201 tggatcgacc gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta
    34261 atgagataag ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa
    34321 aaatagaaat tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg
    34381 ctttagtaaa gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac
    34441 aagataaagg attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg
    34501 ataaatttat ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat
    34561 tagataaatt aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc
    34621 agcctttaga aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa
    34681 actagaataa tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag
    34741 gcaaatggaa gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata
    34801 tgaagaagcg aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat
    34861 cgcacaagaa tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt
    34921 tggtataaca gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc
    34981 gttttctttt taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa
    35041 ataataagaa aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt
    35101 gtttcccaat gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc
    35161 agtaaaactg aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata
    35221 ataaaaaaag gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata
    35281 aataaagtcc atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat
    35341 ttatccggta aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt
    35401 gaaagaagga gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc
    35461 aataatattc gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg
    35521 aataaaataa atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga
    35581 agttattata gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat
    35641 ctagatacca aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga
    35701 ggaaaaaaat gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa
    35761 agattgatgt aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga
    35821 atcgtaaata tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc
    35881 cgacacgttt attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag
    35941 cattgtcctc ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa
    36001 tttgtttttg acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata
    36061 aggtcctaat tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt
    36121 cttaatcatt tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt
    36181 tgctatcaac atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca
    36241 ataatatcaa ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag
    36301 gagaaaaatc tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat
    36361 ataacaagga ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag
    36421 tggtattttg ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg
    36481 tatacttgat cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa
    36541 accagaggaa gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa
    36601 tgggaaagaa cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt
    36661 gaaaattagc aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt
    36721 tccggagaaa gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga
    36781 ttttattatt cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa
    36841 tccccctgca aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa
    36901 ttgggatggc agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt
    36961 tggctacatc ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt
    37021 atttttcttg atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt
    37081 ctaatccagc aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat
    37141 attctttgac aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa
    37201 agcgagtata ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact
    37261 cttgatctgc gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg
    37321 tagcaggtct gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct
    37381 tgcagtcacg gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt
    37441 tttccattat ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt
    37501 gaattactag cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga
    37561 aaaatcgttg atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt
    37621 ttctttgtca tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc
    37681 attatttgtg gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac
    37741 agaagtccag acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc
    37801 ggtttttgga aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg
    37861 gggaacatag acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt
    37921 aggatcgcca tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa
    37981 ctggttttta gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc
    38041 acagccattt tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac
    38101 ttctgctttc tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat
    38161 tgtatgttct ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc
    38221 tgtgccccct agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt
    38281 tcagctgttt atctttccta ttataaatgt atttttattg gaaatggaag tattatattt
    38341 taatatgtag gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct
    38401 tctaaataca acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa
    38461 ggttgatttt taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg
    38521 taatgtggag aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat
    38581 ttaggagaac aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt
    38641 gtatcaaaaa tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa
    38701 gaattattag atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga
    38761 aaacaattgg acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt
    38821 cttttcctat tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg
    38881 gttctattgt ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa
    38941 attatttatc ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca
    39001 ctagtcattt ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc
    39061 ttgtcagcaa tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga
    39121 cttgttttga atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta
    39181 ttatatcagc caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga
    39241 ggaccgatgc tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc
    39301 ttaaacgatg aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga
    39361 caagatgttt gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa
    39421 gcgatcggca tcgttcatgt attctttttc cccagccggt gtttctggtg aaccgaatac
    39481 taattgcgaa cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc
    39541 aataactggg ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca
    39601 agtattagct gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata
    39661 taattcaaat tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt
    39721 accataacca tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg
    39781 agtcaatggg cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa
    39841 aaggataact gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc
    39901 tttgatcaaa gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat
    39961 tgaacggcgg tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt
    40021 tgcgttttgc atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag
    40081 taaacagata tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat
    40141 cgttatgtaa ggattttctt agttatcgct ttcattgttg tgttttagga atttttgctt
    40201 atttgaaaaa aacagctgat atataattat taaatctcta tcttcttttt tttatgatat
    40261 tgccattaaa aattacttgc ttttatagaa aattagttta tatttcttaa ataagttttt
    40321 tagttaaatt tttcggtaaa gatgtataat attttctgaa aatttaaaga attggggtat
    40381 agattatgga aaaacagcaa gacaagggct tcttcgggca gccgaaggga ttgtcaactt
    40441 tgttcttcac tgagatgtgg gaacgattta gttattacgg tatgcgtgca ttacttatct
    40501 attatatgta cgatacagtt gccaacgggg gacttggatt accacgagca acagcattag
    40561 ctatcatgtc gatctacgga tctttgatct acatgtctag tatcgtcggc ggatgggtat
    40621 ctgaccgagt gttaggagca aaacgcactg tattcttcgg tggagttttc attatgcttg
    40681 gccacatcgt cttggcttta ccatttggtg taagtacatt gtttgtttcg atggcattga
    40741 ttattatcgg aaccgccttt ttgaaaccaa atgtttctgg catggtcgga catctttatt
    40801 caaagactga cttgcgaaga gatgcaggat tttcgatttt ttacatgggt gtcaacttag
    40861 gggcattatt agcaccacta atcgttggta caatcggtca agaatataac tatcatttag
    40921 ggttctcttt agctgctatt gggatgttct ttggattatt acaatacatc atccaaggac
    40981 gcaagacatt agacggagtg ggtacaacac cgccgaatcc tttgacaact gaagaacgta
    41041 aaggattcat ccgtaacttg atcatcgcac ttgttgttat cgctgcagta ttcggcgggg
    41101 cacaactaac tggtcatctg acaattgact tttttgtcaa tacaatcagt gtattgggga
    41161 ttatcttacc gttgtattac tttatcaaaa tgctgacttc aaaagatgta actgctgaag
    41221 aaaaaccaag agtatgggct tatatcccat tattccttgc agcaatcatt ttctggtcat
    41281 tacaagaaca aggttcatct atcttagctt tatttgctag tgaacgtaca caatctacgc
    41341 tatttggtgt aacgatccaa gcaagctggt atcaatcatt gaatccaatt ttcatcttta
    41401 ttctgacacc agtattcgta acgatgtgga cgaaacttgg tgaacgtcaa ccatctacag
    41461 tagtgaaatt ctctcttgga cttttatttg caggattatc gtacttgcta ttgatgttgc
    41521 cgggtatgct ttatggtaca agtggaaaag taagtccatt gtggttgttg ggaagtttct
    41581 tcatcgtggt tattgctgaa ttgtgtcttt caccagttgg tttgtctgtg acaacaaaat
    41641 tagcaccacg agcatttgaa tcacaaacaa tcgctatttg gttcttagct gatgcttctt
    41701 cacaagcaat caatgcacaa attgcacgct tctacacacc gggaacagaa tctgcttact
    41761 tcggtattat cggtgcagta gcaatcgtcg gtggtatctt gctatttact gtgaaagaac
    41821 caatcaaaaa actaatgggc tctattcatt aatcaatgaa cataaaaaca ggaattgctt
    41881 atttgcagca gttcctgttt tttgggctct ttgtcaataa ggactgatga gttgtgcaaa
    41941 atcaaatctg agtcagaatg aaccacattc tggctcaga
//
LOCUS       DAIGUC010000022        41608 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.022, whole genome shotgun sequence.
ACCESSION   DAIGUC010000022 DAIGUC010000000
VERSION     DAIGUC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.022"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(71..472)
                     /locus_tag="NOB46_001228"
     CDS             complement(71..472)
                     /locus_tag="NOB46_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI1058176.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(558..764)
                     /locus_tag="NOB46_001229"
     CDS             complement(558..764)
                     /locus_tag="NOB46_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058177.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(859..2361)
                     /locus_tag="NOB46_001230"
     CDS             complement(859..2361)
                     /locus_tag="NOB46_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCI1058178.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(2379..2834)
                     /gene="argR"
                     /locus_tag="NOB46_001231"
     CDS             complement(2379..2834)
                     /gene="argR"
                     /locus_tag="NOB46_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI1058179.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(2932..3549)
                     /locus_tag="NOB46_001232"
     CDS             complement(2932..3549)
                     /locus_tag="NOB46_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCI1058180.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAISNAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            3770..5143
                     /locus_tag="NOB46_001233"
     CDS             3770..5143
                     /locus_tag="NOB46_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1058181.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            5218..6330
                     /locus_tag="NOB46_001234"
     CDS             5218..6330
                     /locus_tag="NOB46_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCI1058182.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(6402..8038)
                     /locus_tag="NOB46_001235"
                     /pseudo
     CDS             complement(6402..8038)
                     /locus_tag="NOB46_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
     gene            complement(8206..8814)
                     /locus_tag="NOB46_001236"
     CDS             complement(8206..8814)
                     /locus_tag="NOB46_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1058183.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(9198..10349)
                     /gene="queG"
                     /locus_tag="NOB46_001237"
     CDS             complement(9198..10349)
                     /gene="queG"
                     /locus_tag="NOB46_001237"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCI1058184.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(10368..11120)
                     /locus_tag="NOB46_001238"
     CDS             complement(10368..11120)
                     /locus_tag="NOB46_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058185.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(11261..12211)
                     /locus_tag="NOB46_001239"
     CDS             complement(11261..12211)
                     /locus_tag="NOB46_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI1058186.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(12212..13051)
                     /locus_tag="NOB46_001240"
     CDS             complement(12212..13051)
                     /locus_tag="NOB46_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI1058187.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(13048..13794)
                     /locus_tag="NOB46_001241"
     CDS             complement(13048..13794)
                     /locus_tag="NOB46_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI1058188.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            14032..15402
                     /locus_tag="NOB46_001242"
     CDS             14032..15402
                     /locus_tag="NOB46_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1058189.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(15457..16353)
                     /locus_tag="NOB46_001243"
     CDS             complement(15457..16353)
                     /locus_tag="NOB46_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1058190.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(16467..16637)
                     /locus_tag="NOB46_001244"
     CDS             complement(16467..16637)
                     /locus_tag="NOB46_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058191.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(16634..17311)
                     /locus_tag="NOB46_001245"
     CDS             complement(16634..17311)
                     /locus_tag="NOB46_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI1058192.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(17402..18307)
                     /locus_tag="NOB46_001246"
     CDS             complement(17402..18307)
                     /locus_tag="NOB46_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI1058193.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            18482..19936
                     /locus_tag="NOB46_001247"
     CDS             18482..19936
                     /locus_tag="NOB46_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1058194.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            19952..20983
                     /locus_tag="NOB46_001248"
     CDS             19952..20983
                     /locus_tag="NOB46_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI1058195.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            20990..22177
                     /locus_tag="NOB46_001249"
     CDS             20990..22177
                     /locus_tag="NOB46_001249"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCI1058196.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            22333..23715
                     /locus_tag="NOB46_001250"
     CDS             22333..23715
                     /locus_tag="NOB46_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI1058197.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            23842..24072
                     /locus_tag="NOB46_001251"
     CDS             23842..24072
                     /locus_tag="NOB46_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058198.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(24272..24940)
                     /locus_tag="NOB46_001252"
     CDS             complement(24272..24940)
                     /locus_tag="NOB46_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCI1058199.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(25129..25926)
                     /locus_tag="NOB46_001253"
                     /pseudo
     CDS             complement(25129..25926)
                     /locus_tag="NOB46_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(26207..27586)
                     /locus_tag="NOB46_001254"
     CDS             complement(26207..27586)
                     /locus_tag="NOB46_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1058200.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(27761..28930)
                     /locus_tag="NOB46_001255"
     CDS             complement(27761..28930)
                     /locus_tag="NOB46_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1058201.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(28905..30056)
                     /locus_tag="NOB46_001256"
     CDS             complement(28905..30056)
                     /locus_tag="NOB46_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCI1058202.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(30016..31377)
                     /locus_tag="NOB46_001257"
     CDS             complement(30016..31377)
                     /locus_tag="NOB46_001257"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCI1058203.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYGTVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(31374..32375)
                     /locus_tag="NOB46_001258"
     CDS             complement(31374..32375)
                     /locus_tag="NOB46_001258"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCI1058204.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(32391..33086)
                     /gene="dapD"
                     /locus_tag="NOB46_001259"
     CDS             complement(32391..33086)
                     /gene="dapD"
                     /locus_tag="NOB46_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCI1058205.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(33092..33808)
                     /locus_tag="NOB46_001260"
     CDS             complement(33092..33808)
                     /locus_tag="NOB46_001260"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCI1058206.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(33805..34686)
                     /locus_tag="NOB46_001261"
     CDS             complement(33805..34686)
                     /locus_tag="NOB46_001261"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCI1058207.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(34689..35489)
                     /gene="dapF"
                     /locus_tag="NOB46_001262"
     CDS             complement(34689..35489)
                     /gene="dapF"
                     /locus_tag="NOB46_001262"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCI1058208.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(35476..36735)
                     /gene="lysA"
                     /locus_tag="NOB46_001263"
     CDS             complement(35476..36735)
                     /gene="lysA"
                     /locus_tag="NOB46_001263"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCI1058209.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(36950..37120)
                     /locus_tag="NOB46_001264"
     CDS             complement(36950..37120)
                     /locus_tag="NOB46_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058210.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(37221..37784)
                     /gene="efp"
                     /locus_tag="NOB46_001265"
     CDS             complement(37221..37784)
                     /gene="efp"
                     /locus_tag="NOB46_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCI1058211.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            38212..39129
                     /locus_tag="NOB46_001266"
     CDS             38212..39129
                     /locus_tag="NOB46_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCI1058212.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            39142..40287
                     /locus_tag="NOB46_001267"
     CDS             39142..40287
                     /locus_tag="NOB46_001267"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCI1058213.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            40458..40916
                     /locus_tag="NOB46_001268"
     CDS             40458..40916
                     /locus_tag="NOB46_001268"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCI1058214.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            41075..41545
                     /locus_tag="NOB46_001269"
     CDS             41075..41545
                     /locus_tag="NOB46_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCI1058215.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT        11688 a         8594 c         7586 g        13740 t
ORIGIN      
        1 tttgtcaaaa aaaaccagac aaaaagcggt cctttcacgt ttttagtctg gttcgatttc
       61 ctttattctt ctaaacaatc gttacttcta catcgatatt tcctctagtt gctttggagt
      121 aagggcagaa ttcatgcgca tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat
      181 cgatatgcac ttctaatact acaccgatct gatagccgcc atcatctaaa ttataaagag
      241 agacacgtgc ttttactgtg gactctgctg tcattcctgc ttctttgatc atatgttgta
      301 ccgccccatt gaaacaagaa gcataacctg ctgcaaataa ttgttctgga tttgttcctt
      361 ctgcatggat tcctggagga gtgattttca tatgcatcga gccatttggt gcctcgactt
      421 ctccattgcg cccgccatgg ttgatcattg ctgtttcgta tgcttttttc attgtactgc
      481 tcctttcgat tgaccatttg ctacttggct ataattatag tgtatgacaa gtaaggcgct
      541 ttctacaaaa attctgctta ttcgaatacc agaatgccgt cttctactat ttttccaaaa
      601 aacaaaaaaa tactactcgt gaacaacagc gtcatatttg ttccaaaata aatagcaatc
      661 ttttctacat aatcttttat atgattgatt ttaagataca tatataccag aaagttgacc
      721 ccataaacca atactgttaa aaaaataacc atattcgtta ccattttttc ctccttttgc
      781 tggtctccct accagcactc gatttaacca taccactttt tttgccgtcc aagcaactag
      841 cctttcaaaa agactggttt attctgctgt taatgattca agatcagaaa aatgtccgaa
      901 taattttgct aattttacta acgccaactt gttctttccg aattcatcat tttctatctg
      961 taatactagt aacggctcat gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg
     1021 ctcttctaga tcatatcgaa taccttcttc attttccggg tcgaagttca tccctttttc
     1081 ttcttccaac agtcgcttca tttcttctaa tatcttgttt ccttgttcgc gtggttcatc
     1141 gctgaacaat tttaatcgga tttcttgtac ttctacgggc tgtttcaact ctttgatttg
     1201 ttcatctaat gtgatacctt ttctttttaa ttctggcaaa agcatcagga tctttgcgat
     1261 gacatatgca ccatcatcca gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc
     1321 gatggctagc tgtgtatctt tcccaagacg gttaagttct aatgctttat tgattacatt
     1381 tcgatagccg gaaatataac gaacttggat gcctcctttt tcttcaatga atctttgtag
     1441 atgagaagaa gtaggggaat tcgtcacgat tcttgttcct ggatgctctt ttaatacgat
     1501 tgtacttaat actgcgatca aattatttcg attgatcact gttccagaag cactgacaac
     1561 tgcagaacga tccacatctg tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac
     1621 agcctgcttg atactttcca tcgcttcttt attatcagga tttgggatat gattaggaaa
     1681 tcggccatct ggttccaaaa attgggaacc tgttgaatcc gcacctaagc tattcaatac
     1741 tttttcagca aagaatccac cagcaccatt tccggcatca acaatgattt tccaaccatt
     1801 tagtggtttg ctttctagtg ttccaatccc ctttttaatt tttgtgacta aatcttgcgc
     1861 ataaggtgtc aaaaggtctg ctttttctac gcttccagtt tgttcgcttt ttattttttg
     1921 ctgctgtgat aggataaaag caatatcttc tttttctgct cctccttctg aggtaaagaa
     1981 ttttattcca ttataataat agggaagatg gctagcagtc agcataaccg cagcatcgca
     2041 cgagaactgt tcaaattgag tggacataaa catagcaggc gtagtagcta attcgaaatc
     2101 gatgacatgt atcccttgtt ctttcagact ttggatcaac gcctctttca gtgctggtcc
     2161 gcttatccta ctgtcatgac caatcccaat cgtccatttt ttatttggat cggttgattt
     2221 cttctttttc tttatccagt ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt
     2281 caagtttact tcatatcctt caactggtaa tgcgattcct cgaatatccg atccattttg
     2341 cagcgctttc atatctttca tataaaagtc ctcctcattt attccctcat tttttccagc
     2401 ttttctgcaa atcgctgtgc ttcttcttct gagcggcaaa taataatgaa tgtatctaca
     2461 ccggccatcg ttccgacaac ttcagggtaa gccacttcat ctagccaatt cgttaccaca
     2521 tcggcaccat ttcgttcagt caatacgata accatgaact gaacagactg gatacgcaaa
     2581 acctcgcgtc taattgctgt acgcaaacgt tcttcattta aagaaacaga tggctggtta
     2641 aataatgtat agcgtactat tttgttttca ttttgacttt ttactaactt catttctcga
     2701 atgtctcgag aaatcgttgc ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc
     2761 agctcttcct gtgtcccaat aggttgttct gtaatgatct ggcggatcag tgcttgtcgc
     2821 tgtttctttt tcatattaga cacctctcaa tgttgattat agcaaaagat aagtaatatt
     2881 tcttcatatt ttggtatttt ttacttttat tttttgtttt cattcaggtt gctaaccttt
     2941 ttctatttta acacgcaaaa tcgtcttcat tttttcaggt gctgattttc ttggatcgct
     3001 gatgtaaatc tctttgtgtt ctttagaagc tctttcatag ccttcttttg cgatgaatgc
     3061 ttctaatttc tcaaacgttg ctggttcttc ggcatagggc ccgacgtgta agatttgggc
     3121 acaaagacct tcttccatct ttttgaatac tacttgttct ttcaagtctt ccggaagttt
     3181 gctagaacgc tgaatggctt cttgtgctat cgcttctgta acaaagtcag gctgtcggat
     3241 catcaattga taagaaaaat gttctttttt catcactggt tcatgcaaat acttttcttg
     3301 cagtccccat tgtccttcca gtggatagac agtatacatc tgataatcag gaatcagcca
     3361 atttttttta ggcgacatgc gtattgcatt gctgattgca tatagacagg ctactcttcg
     3421 tttaaagtct tcctgattcg ggtcgccgat ccctctgatg ctaaagaatg attttttagg
     3481 aacctctagt atttgcgggc tttttttcat actatagctc ttatctttac gccattcaat
     3541 tttttccatt tttcttcctc cgcgaaattc catttagtta tttattatca tacctctttt
     3601 tgagtgactt ggctaatcgt gttgacacta tttttcagtt tgtgctagaa taagtgaagt
     3661 aaataaatcg tacagataac acgtttcggc gtgtcgagag agaggcggtt tctattttta
     3721 taatagaaat cactctcttt ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca
     3781 aaaacagctg cttttagtac ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt
     3841 attgatcgag acggccatga atgtaacttt cccaactctt atcagacagt ttgatttaac
     3901 gactgcacaa gtccaatggg taacaacgat ttatcttttg atgatttcga tcattgttcc
     3961 gctgtctact tatttgaatc gcaattttag tctcaaaaaa ctctttttag cttcaaatct
     4021 gcttttcttg gcaggtataa tgatcgattt cttctctcct accttcatgg tcctattgtt
     4081 tggtcgattg ctccaaggtg cagcgacagg tatcgctctt ccgttgatgt tccatattat
     4141 cttgacattt gcccccctca atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac
     4201 ggccattgct ccagcaattg gccccactta tggaggcatt atgacttcac attttacatg
     4261 gaatcatatc ttcctgtttc ttgtgcccgt tttgtttctt tctttgatta tcggctggtt
     4321 tgctattccc gagatggcag tacaaaaaag tggttatttg gattggataa gcgttttagg
     4381 aatttgtctt ttgtttagtg gaagtctaac atttttgagt acgttgggaa cagtttccag
     4441 ctggattgct ttaatcatcg gcggtattgg ctggttcctt ttttactatc gaagtaaaaa
     4501 agtggagcat ccactgatcc gactgtctat tctttcaaat aaaacattcc gcttgttttt
     4561 gattggcttc ttagtttatc agtttttatt acttggtgta tcttttgtct tgccgaattt
     4621 ccttcagatc gttcaaggaa gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc
     4681 agcggttggt gctttgcttt ctcctttttc cgggaaaatg ctggatcaat atggtccgaa
     4741 gaagccaatt tttgctgggc tgattctttc tttgattggt tggctagcat tattcctact
     4801 cataggacac gcttcagtgg gtgtattgat tgcttgtcat gtgttttata tgatcggtat
     4861 cggattatct tacagcaata tgatgaccac cggaatgaat gcactgaatg aagaactaca
     4921 aggagacggg aacgcaatgt tcaatacctt gcagcagttt tctggcgctg tggctacttc
     4981 attagtagcg gtcattatca attacgtcca gcatcatact tcccataact atgaagtgtc
     5041 tactacatta ggatcaaaag cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt
     5101 tgctcgattc gcctattatc tgttctttgc taaaaaagcg tagattccat atacggcagg
     5161 tgttgcatct gccgtttttt tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg
     5221 gaaaaaattg ccattatcgg tggcgggatc attggtatga ccctagccag ttacttagat
     5281 acatcaaaat tcaatgttgc tttatttgat gaagggacag gacaggcaac taaagctagc
     5341 gctgggatta tctccccttg gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct
     5401 aaagacggcg ctgctttttt ccctaaactt ataaaagatt tccaacttga tcaaacgatt
     5461 tacgcacaat cagggacact tttgcttcga cctgaaaaag atttagctga attggctgtt
     5521 cttgccgaga aacgaaaaga agaagcgcca gaaattggaa acatcgaatg gctttcacct
     5581 gaacagacat ctcaagcact tccgttattg aaaccagcag tttcactgcg tatcagtggt
     5641 ggtggtcgtc tggatggaaa agcatattta gaacatcttg gtcagcgttt agcacaaaaa
     5701 caaatggagc agatccaggc aaaagtcact ttgcataaga agagcgattc ttggctcatc
     5761 aagggaccgt ttggagaata cacagctgat cgtgtaattt tgacacctgg cccggcactt
     5821 aagcctttat tacaagaatt aggctatgct gcagatatac gtccgcaaaa agggcagctc
     5881 ttagcatttc agacatctta taagatgagt caagactggc ctgttgctat gcttgacgga
     5941 gaagctgatt tcattccttt catggatgga aagatccttt taggtgctac ccatgaaaac
     6001 gatcaaggct gggatttggc tcctactagc gaagcttata agggattgac taagagtaca
     6061 gaacagttct tgactgatcc agatcagata aaaaactggc catacgagtt ccgtgtaggt
     6121 acccgtgctt atacgtcaga tttttcccca tttttcggcg tactgccaga tgatccaagc
     6181 ttactggctg ctagcggtct aggctcttct ggcttgacca caggtcctta tatcggctat
     6241 ctattagcca acttcttaaa tactggtcat tggcctacgg aagattatca aaaggacatc
     6301 tccacctata ttacgaaaaa tccatcatag aaaaacagct ttttcaagta aggatcccga
     6361 gcgatattgc gcatggatta cttcttgaaa aagctgttat tttagttcaa tttctgaatc
     6421 aaattctcca aactttcttt tgcttcatct ggcaagagat cttttcctat ctgagcttca
     6481 atgaatcgta aacgaatatc aagtcgttgt ttcaccagat ttttatagga cgtatcctca
     6541 aaagaaacag gaaaatctgg tataggtaaa tagtggatgt cttcaaatgg accaaacgac
     6601 ttgaattctg ccgtttgttg cacgattctt tcaacgattg acaatgtcgt ttcaggtttg
     6661 atttttttat catcgaaata tccagtattc aggacatagc aggctgtttg ctgtttcaaa
     6721 aacaactctc gaaaagcttg atagtcttcc ctaagaggat agacacggaa aggattagca
     6781 aatggttcaa tgactagctc atctagctgt ctttttgtag tgatattttc cgcgtctgat
     6841 cgttttgttg ctaatgttgc accaaaagac gctgctaaaa ctgggtcatt gatcttgata
     6901 attggcggaa gcgaatcatc tttcatgatc caaaaaacag catcgatctt ttcgctaaga
     6961 tgatcgactc ggtcgggtgt cgcataacgt gatttgactg tccgcccatt tccgtttcgt
     7021 atatctcctg ttactaggac tttttctcct ttacttgtac atgtcacgcc cacattctga
     7081 caagtaagga aagaagaaat ggccggatca tcagacggat agtcttgtgt tttatcaaag
     7141 taagaaggtt ccaaggcagt agcaaaacca ttttttcgag aaataacgaa agcatcgtca
     7201 tgcaagatcg aaacagagtg accttccgta tgttttgcta aggtaatcgt tgattttcca
     7261 gaaccggaca acccaaatac agccatcgta taggtctggt cattactagc atattgtttc
     7321 atcccaccgt ggcaggcaat aaagccattg cgatttccca atgcccaagc aagcgtcaaa
     7381 gtcgcttttt ttaattctcc aaagtaacgt aatcctagca cagccgctgt attatggaga
     7441 gcatcaaaca aaatgagtcc atttggaaat gtttcatgtg tccattcggg atcacaaaag
     7501 atataaagat ctccctcatc aaaggaaaca gacttttgat aagtctctaa gatcttcgaa
     7561 ttcgctggct gaaaattcag caaataagaa tacaaattgt tctcaaatcc ttctggaatc
     7621 agcaaatgac tttgcacaga aatttttcag ataggccaac gattactttt gtatggtaaa
     7681 actggcgctt gcgactttga tacacagctt ctcttaaaat tttctcgtat ttgctttgtt
     7741 ccttgtctaa gtcctcaaag atccgccgag cacttgctgt tcttcccaca atgcttccat
     7801 cattgaatac tagtgtccta acatcagctg gtaaatatag ttcttcagca tgtgagattg
     7861 ttaaatctgt gatgatcgtt cctggactcc cttttgctag ttgataagct gtcttcctat
     7921 caaaaacttc atgaacatta ttaccgtaaa atgtcgtttc tacaatcgat cgaatactgg
     7981 ataacagtgg atttccactt gtgatttcgt ttaattcgag actctctttt gtactcatgg
     8041 ctcctcctca ttccctaaac aaaaaaacgt tttctttatt atacattatt cgagttttta
     8101 tttgtactgc tgcgctgtgg gaagcaaacg agttattttt cacacaaaaa aaccgagaac
     8161 ttgaataaac aagtttctcg gtttcatcat tttcctttta tcggcttagt accagccgtt
     8221 tgctaaccag aatgttttag cagcatccca tgaaccataa cgagatgtta catattgttc
     8281 tgctacacgt tcttgattgg cagctgaata gtcgccgttt aagtatgaag catctaattg
     8341 ataacggccg atgtaacgtc cgttagtagc tgtgtatgaa ccgcctgatt ctttttgtgc
     8401 gatccattct tttgcagagc ttgaagttgg cgctgttgca gcagctgggg cagcaggagc
     8461 tacttcaact gtttcaacag gtgcaacgta tgtatgttct tgcgttgctg tttcagttgt
     8521 agatgctgta ttttctgttg ttttgttttc tgttgttgct gaagaatcat ttgaagttgg
     8581 gattgttaat tgttcaccaa cataaatgcg gttgatgttt gcgatcgaat ttttttcagc
     8641 aattgcatcg atcattgagt tgtctcctgc aaatttttgt gagatcttag ataatgaatc
     8701 acctgatttt actgtataaa cttcatcagc gtgagcattt gtagttccta caaacattgc
     8761 agtagcacca gcagcaaaag ttgtacctaa aacaattttc ttaaatgaat tcatattaaa
     8821 ctcctttttt tctccgtttt ttattctttc gacgctatta actttatcat ttagaaatat
     8881 ttcataggta aaagaaacat gacatttaat gacaaaataa cgaattattt aatatttgta
     8941 acatttaaac aaatattttt ttgatacaaa accataaaag ccttgttgta taagcaaagt
     9001 aatcgttttt ctatgttttt ttatttttga atgaaaaacg cagattctgt aacattcact
     9061 gcaataatcc ataaaaaaaa gcaaaaaaat ttttgatttt tatcaaattc tcttaaaaaa
     9121 atgtaaaaaa tacaaaaaaa ccagtaattg ttacaacaat tactggacaa aaactttgaa
     9181 taatgttaac tattttttta ttttaacttt ctccgcaata atttctgggc atgttccaat
     9241 tcgtttataa cgacttcttc tgtttcttta gctaatattt catctaatac atcaagccat
     9301 ttttccggtt cttttgttcc tagacgtcca atagcccaag ctgctgttcc tctgatgaca
     9361 gggcggacat ctgttaaaca ttctgaaatc tcaggcaatg ccgttcgatc acctagatta
     9421 gctaaagcaa tcaatgcgtt tctctgcaaa ggtttcttcc cacgccatga accagctaaa
     9481 tgcccaaatt gctgtttgaa gtctttatta gacatcgaaa gcattggctt taattttgga
     9541 tatatttcgt ctacttttgg ttccatctct tcatgaaaat gaaaatcttt tccttgattg
     9601 taagggcaga ctaactggca gatatcacat ccataaatga catttcgcat ttttttacga
     9661 tattcttccg gcatcatccc ttttgtctga gtttgataag acaaacatcg ctgggcattc
     9721 attcttccgt caccaagcaa tgcttttgtc ggacaagcag tcacgcagcg catacagtca
     9781 ccgcaaccaa attctcctgg tttatcaggc tcaaatacaa tattagtaac gatctcacca
     9841 agatagacaa atgaaccgaa ctcttcagtg atcaacaatc cgtttcgtcc aataaatcct
     9901 aaaccagctc gctgtgctac agcgacatcg atcagttctc cagtatctac ttgcggagct
     9961 agacgccatt cctcttcttt ttgccatttt tctgctcttg tttggatgaa ttcgatcaat
    10021 cggttcaaac ggtctctgag tatatcatgg taatcgatcc cccaagaagc acgagcaaac
    10081 tgcccgcgtt tttcatccct aggcacttct tcatggatcc tagtaggata cgcaagtgca
    10141 atggaaatga tcgatttcgg ctgatcaaat gtcatttctg gataaagacg ctcatcgata
    10201 tttggatgtt caaagccaga agtatggcca gctgcttttt gttcttccaa cgattctttt
    10261 aatgaatcaa aaggttccgc cgtggtgaac ccgattttgt caattcctaa tcgtttgctt
    10321 tcttgtatga tttcttcttt taatgtcatg gtcttcctcg cttgctgtta acggctgtat
    10381 aacccataat atagtttttc ttttttcagc tggacaaact ggatctgctg atcggcaatc
    10441 ttcttttctt ccatccattt ttttcttgca gcaaatactt cccaataatt tgttgaaatt
    10501 aattttcttt tgttatctaa tgcattaaaa aaattcaatg aaactggttt tgtacttaac
    10561 agttcatgga gccttacctc ttcccatggc gaaaactcag acagatcgcg ggaatacaat
    10621 acttcttcat agagattttt ttgctgtgtg tacgtgaatg tttgcgggat tttcccaggc
    10681 ctagcaattt ctactagacg attataaaac atattcatta atttgctgtt ggcaataaat
    10741 tgacttttat aataggccga ctggatcttt ttgattactc cttctgcttt gatgactgaa
    10801 aataatgcag gccatgcttt gacggttatt tcgtcgtttt gtttaactaa tacgccaggt
    10861 gtgaagccga ctggagaaag gaacacaaaa taaccgatac cggtattttc atctaaaggc
    10921 tgaaattcat caaacaacca tttgcctatg tacagctctt catctggttc tgttgtctca
    10981 ttttgatttg ctatgaataa tttagctaat tctgcttcaa gaaattgaag gtcttgatcc
    11041 ttgtcggtat tttcctgctg gctgatcaat cgaaagactt cttctttaat cgtatattta
    11101 tctttacgtg taaaattcat agccacacct tccttcctta ctctaactat aacggaattt
    11161 cttcaaaaaa ggtatctgta cgacgaaaaa cagcataatt ttttttcata tctcttataa
    11221 aaaatgcaag gtctgctcct caagctagac cttgcacttt tcagctttct tttgtttgtg
    11281 acaaaccttc atggatcgtt tcaatattcc atttcatcat ctgatagtaa gaatctcctt
    11341 gttctccttc ttttgctatg gaatcagtga acagtttatc atagattttc aaacccgttt
    11401 cttttgctac ccgttccatg cttcttgagt ctacactggt ttccacgaat aaaaccggta
    11461 cttcttttgc tcttatctga tcaatgatcg ctttcatttg atcaggcgta ccttgacttt
    11521 ctgtattgat ctcccatata taagctgctg gcaaatcata tgctcgtgaa aaatacttga
    11581 atgccccttc acttgttact aataattttt tgttctcttc gatagaagca aaactttcct
    11641 tcgcttgtgt atctaattct tttagttttt ccacatatgc ttctgcattt tttttataga
    11701 gtgtcgcatt ttctgcatct ttttcagaga atatacgtgc gatttcctcc acatatttta
    11761 ttccgttaga taggtctagc caagcatggg gatctgcttt tgtatgttct tcaccgctag
    11821 ttaaataaag aggttctaca tttttgctaa ctgcaaaata atcttttcct tcttcttttt
    11881 tagccgtttc catcaagtta tcgaaccagc tgttacctgt ttcaagattc aaaccgttgt
    11941 ataaaataac atctgcatcg cttgcctttt tgatgtcttc tggtagtact tcatattcat
    12001 gcggatctgt tccgactggt acgatactgt ggatatctat ttgatctgtt ccgacctctt
    12061 ttgccatgtc cgccaagatc gaattggtag ccacgactga caacttttct ttacttcctt
    12121 catccgcttg gtcagaagcc tgctttccgc aaccggctaa taccaagaaa ctaactgcca
    12181 agattaaaaa gagtgatttt tttgttttca tctatctgct tcctttctga aataaaattc
    12241 cttttgttgg agaaaataaa aaagcaagga taaaaaatgc ggtacatgct aacacgatcg
    12301 tagctcctga tggccaattg taactataac tgaaaaacac accgacaact gcacttagca
    12361 taccgattcc tgcagctgta atgatcattt tcagtaaatg gttcgttagc aagtaagccg
    12421 tggcggctgg tgtgatcaac atggcaatca ccaagattgt tcctactgtc tgtaaactga
    12481 ctacagccac taatgtcaaa aagaacatca aaagataatg gatcagcgat gtgttcagcc
    12541 cataagcttt tgccattgtc ggatcgaatg atgtgatctt caattcttta taaaagaaaa
    12601 agacaaatat caagacgatt ccactaacga gtgctgtcag caacaaatcg ctttccctaa
    12661 cagctaagac attcccaaat aaaatatgat acaaatctgt cgcactctgg gcatatgaaa
    12721 tcaagataat ccctaatgca aaaaaggagc taaagacaat tccaatcgct gtatcatttt
    12781 tcaatcggct ccgctgagtc acgaaaccaa tcactgctgc tgttagcatc ccaaaagcag
    12841 tggctccaaa gatgtaacta aaaccaaaca tataagaaat ggctacacct ggaagaactg
    12901 cgtgagagat agcgtctccc atcaaagaca tccctcgtaa aataataaaa gaaccgatga
    12961 ctccagaagc aagtcctaca agcatggaag tgaccaaagc gtattgcagg aattgataat
    13021 tcattaatcc atcaataaag gattggatca ttttttctct cctcctttta ctaaatgtct
    13081 gatgatctca ccataggcca attgaaggtt cttcgatgta aagacttctt gtactggacc
    13141 ggaagcgatc agctgtttat ttaaaagaat aacctcatcg aaatattctt ctactttatg
    13201 aagatcatga tggacgatca aaatcgtttt tcctgaattc ttcaattcct gcaagatgtc
    13261 aaagatcttt cgttcactta acgcatcaat ccctacgaat ggttcatcta aaaagatcca
    13321 ttctgctcct tgggctagag ctcttgcaat aaaaactctc tgaagctgtc cacccgatag
    13381 ttcgctgatc tgtcttttgg catattcttc catccctact tttttcaaag cttgtcttgc
    13441 acgttctttt tcttttttcc caggtctttg tccaattcgt aaagatggat atgttcctaa
    13501 aagtacaacg cctaatacat caattggaaa ggaaagatcc aattcacttc gctgttccac
    13561 gtaggctatt tttttacgga ctgagtttac cgactgtcca gaaaaggtga ctttaccagt
    13621 agtagctggt atcaactcta gcaaagattt cataaatgtt gattttcctg caccgtttgg
    13681 tccgataata ccggtaattt tttgtggatt tatcgtcaag ttgatagttt tcaaaacagt
    13741 tttcccttga taagcggctg aaaggtcttg aattacaatg gccgtacgtt ccaaatctta
    13801 cactcctttt taggtttacc taacttttta tttaaatata gtttaactaa aatggaaagc
    13861 attttcaagt agaatgatga aaaagttttt ttcgaatttt cctcgcattt tatgaaaatt
    13921 ttctgtagaa tcacatcaag agttcaataa ggctaaccta ataatgaaaa acatgtgttg
    13981 aaacgtttga ttattttttc ttgttgactc aacaacgaaa ggagtttttg tatggaagaa
    14041 gaaaagttaa ctcgaagtct tagtgcccgt catatccaaa tgatcgcact aggtggaacg
    14101 atcggtgtcg gtctgtttat gggtgcctcc tcaaccatac gttggacagg gccctcagtg
    14161 atgggagcct atgcgattgc aggattcttt ttgtatttga ttatgcgtgc tttaggcgaa
    14221 atgctttacg ttgatccttc gactggttct tttgcaaatt acgcgagcga gtacatccat
    14281 cctgtggctg gctacttgac cgcttggagt aatatttttc aatatattgt cgtaggaata
    14341 agtgaagtga ttgctgtagg atcttatatg aattattggt ggcctgattt gccggcaatt
    14401 attcccggaa tcattgtcgt cttgtttctt atgctggcaa atcttatttc tgtcaaggcg
    14461 tttggcgaat tagaattttg gttttcgatc atcaaagtca taacgatcat tttgatgatc
    14521 attgcaggtc ttggggtaat cttatttgga tttggtaatc atggtcaggc agtagggatt
    14581 tcaaatcttt ggaaaaatgg tggattcttc actggaggcg tcaaaggatt tttctttgca
    14641 ttatcgatcg ttgttgcttc ctatcaagga atcgaactga tcggaatgac tgctggtgaa
    14701 gcagagaatc ctaaaaagac gatcattgaa gctgtccagt ccactatcgg tcgaatcttg
    14761 attttttata ttggtgctat ttttatcatt gtgagtatct atccgtggaa tcaattgagt
    14821 gagattggtt caccttttgt acaaactttt tctaaagtcg gcattacatt tgctgcagga
    14881 ctgattaatt ttgtcgtgat tacagcggca ttatcaggtt gcaattcagg gattttcagc
    14941 gcaagtcgta tggtctatac acttgccata aatggaaaga tgtctaaaaa atttctgaaa
    15001 ctatctcgtc acggtgcgcc tttttatcct gtcgtagcaa tctcaggtgg aatcttaatt
    15061 ggtctgatct taaattatct tctaccaatg ttcatcaacc agtcagaaaa tattttcgtt
    15121 ttcgtataca gctcaagtat tttgcctggt atggttcctt gggtagtgat tttgatcagc
    15181 gagattcgct tcaaaaagaa gcacgcagat aaaatgcatg atcatccttt taaaatgcca
    15241 ctatctcctt atacgaatta tgtgacactt gcttttttag ctatcgtatt gattttcatg
    15301 tttatcaatc ctgaaacgag aatctcattg attattggac tcgttttctt gctttacatg
    15361 acgatccatt actttgtacg cgaaaaaaga accggaaaat aaaaaaagaa cgaagcttca
    15421 ccttagtgga agcttcgttc ttttttattg cttttatcaa ttcaatttta gcgtctcacc
    15481 gggagtcagg aaataattct ccatgctcat cccattcagc gacaagatcg tttctactgg
    15541 tacgccagtt cgttcggcta tttgatttgg accttctcct tccaaaacta cggttgtcgc
    15601 agcctgtgaa gtcgcgctgt tggtattagt ttcagaggaa tctgttgtgt cttgtgttgt
    15661 tcgagcttgc atttcagaag cttctaccga ctctgctgtc tcagaatcag aagatgttgt
    15721 gtcttgtgtg cttgttgact ctgcttgaag agaggcgcta gtctgcaaat aaatatcgga
    15781 aatcttagcg acatgattcg tataattagc cgataattga ttgatcaaag tatctaagtc
    15841 tacaccgtct ttattttctg ctgcctgata cgctgcacgt aattttctga tcccttcgtc
    15901 ggagattgct tgaagctcac gtgctttttg gttagcaact gctgataaac cagctattcc
    15961 ctcttgattt ccctgaattt ctgtctggta ttcttcaatc aatgcaggcg tcttttcttc
    16021 gatctttttc gaataatcat ttacgattgc ttgaagttgc tctggcaaac catttgctgt
    16081 tttttcttca gaagtttgtg tctcttttgt tttagttgat gactcacttg tttgtttcgt
    16141 ctctgttttc tttgtcgttg tttccgttat ggtcgtactt ttcgcttctg acgaattttt
    16201 tccatgaaaa tatagacccg caactcctcc tgctatgatc aaaaacacgg caactgctgc
    16261 cccaatcatg atcatccgct tacgagctgc ctgtttttgc tgtcttcttc gggtcatccg
    16321 aacattttct ccccactcat tttcatcata catttttttc accaccaatt tttatgtata
    16381 atagcgttat caaacgcttc atattcttat tgtagcaaat aattgtcgct gtgcacattt
    16441 ttatctttgt tatttataag aaaatttcac cagttgagat gattccaaga ttgtccgtcg
    16501 atttctcctt gcagctgcat tgttcgttcg tctatctcag ccatcagttt ctttatttca
    16561 tataagagcg cacggtcttg atattctgat ttttcgctta attcatctaa ttgttggatc
    16621 agccaatcat ttgtcataat gaagttcctt tcatttcttg cagtgtaaag gtcaagtctt
    16681 cgatctgctc ttttgcctca gtcagtgctt ctacgatata tgcttgtttt tcagattctt
    16741 cttcctgcat tttctgattt tcctgtactc tttgaataaa ccagtcaatc cgctgagtca
    16801 gcgatggttt gccttccaat gagagatact gctgataagc aattagcttc tcccaacgtt
    16861 tttcctggga taaatacata aattgtgcta aaacgaatgg cggaagatag gtcatatgga
    16921 atttatttgc gattcgctga tacggcctca aaaattcgga aatcgtatat tcttcttttc
    16981 ctccagcttg gtattctttt tccgccacac ctgttgtcaa tacgattcct agttctttcc
    17041 cttttaatac atgtgctgct cgttccaaga cattatcttg ccaaattttt aaatgagcag
    17101 gagaactata ccagtaaaac ggaaactgga aaatgatccg atcatgctgg gccaagagct
    17161 gtagttcagt ctctatatct atttttccgt ctggataact tgattccaaa tgatgccaag
    17221 tagctggtaa accagcagaa gcttctttga aaaattgctg atttaaagat tcttcgatcg
    17281 ttggatggct aatgatgata agtgtacgca tcccttttcc tcctttttag tcttcgcttt
    17341 acagtgtagc ataaccgcca caagtttctt ttgccgatgc ttgtcatttt aaccagacta
    17401 atcaggttgt ccaagaaact gcggtttgtt tttccaactg ttttttcaag gtatccaaag
    17461 caatattctt aaaattttcg tttttcatac gtttacgata gttcgtagcc gtttctccgg
    17521 tactcttttt gaacattcgg ctaaatacga ctagactatt gaaccctact tgataggcaa
    17581 tactttccac ggattcatcc gtcagagaaa gaagaaacgc ccctcgattg atccgtaccc
    17641 cgatcaaata ttccttgata ctggtaccca tatgattttt gaatactcgc gacaaatggc
    17701 tccgattgac cgctaaatgc tgggcgattt cctcaacaga caatttttca gcataatgtg
    17761 cctcgatgta tttgactgtt tcaacagcta aagaggaatg aaccttttgt acaccaccgc
    17821 tgacctttcc gccatctttt aaaaggactg ataaaaaacg gtaggttaat gctgttaact
    17881 gtaattcatt ttccaaggtt tcttccgtat ctttcatgca ttctaaaata atgtcgatat
    17941 atttttgtat gtcagaagag accatcgtgt attggtcttc tctgaaaagc gactgccgaa
    18001 tgatttcttc tgcagcactc ccaccaaatg aaagccagca atacatccac ggatcttctc
    18061 catctgataa gtaaaacgtc gagtctcctg gacgaatcaa gaacagatca ccttttttca
    18121 attggaattg ttgatttttc acatgataag atcctttgcc ttccatcacg acatgcagga
    18181 tgtaatcatt gcgaatagca ggaccaaaag aatgaaacgg catcgtttta gagaaaccac
    18241 aaaaatcaaa atacaattct ttttctactt gttgatgttc cttttttaaa aaaatcgatt
    18301 gctccacgtc tatccctcct tactccttta gtataatgca acaaaaagtt aaataaaagt
    18361 cacagaaata tattaaaaag gaagcgattt cttgttaagt ttaagtcatt aaaagatctt
    18421 tgttattcgt tgtaaccggt ttacttagta ttatatattg aacaggagag gaatacagat
    18481 tatgaaaagc aaaatgatcc aacgtgtgtc ctacgcttta ggcgcttttg gacacgacac
    18541 attctatgtt acattaagca cttattttat ggtattcgtg acaagccaga tgttcgcagg
    18601 aacagataag gcaacgaatg caaaaatgat tgctacagtt acaagcttag ttgtaggtat
    18661 ccgcttagtt gaaattattt ttgatccttt gattggtggc atcatcgata atactcgtac
    18721 aaaatacggt aaattcaaac catggttagt tatcggcggc gttgttagtt ccgtactctt
    18781 ggtagcaatc tttaccaatt tctttggctt agctactcat aatacgactt tatttatcat
    18841 attatttgca atcgttttca tcttattgga tagtttttat tcatttaagg atatcgcttt
    18901 ttggtcaatg attccagctt tgagtacgga aacaaaggaa cgtgaaaaat ttgctacgtt
    18961 tgctcgtttc ggctcttctc taggtgcaaa tggtactact ctagtcgttg tccctatcgt
    19021 tactttcttt acctatcttg ttactcataa acatattgaa ggcgcttcag gctggttctg
    19081 gttcggtgtg attgctgctg ttatttcagg cggtactgcg attatcactg ccttgggcac
    19141 aaaagaagtc gatactgcga tccgtcagca aaatgaaaaa gctgggatca aagatgtgtt
    19201 caaagcagtt gctcaaaatg atcagttgat gtggcttgcc cttgcttata tcgcttatgc
    19261 gattgccaat gtagcaacaa ctgccgtatt attctacttc ttcaaatatg tacttggcca
    19321 accaactgaa ttttggatcg ttggtctagt tgctgcctta cttggtttag tagctgttcc
    19381 actattccca atgcttacac gcgtcatctc tcgtcgctac gtttaccttg gagggatcgc
    19441 aatgatgatt tcttcttact ttttctttac gatcgcaggt tcaagtttgc caatcgttat
    19501 catcgggcta gtattgttct acttccctca acaattgatt ttcttatccg ctttgatgac
    19561 gatcacagac tctgttgaat atggtcaatg gaaaaatggt atccgtaacg aagctgttac
    19621 tctatcaatt cgccctttac tagataaaat cgctggtgct ttgtctaacg ggatcgtagg
    19681 gtttgtcgct atcgcttctg ggatgactgg taatgctact gctgctgata tcactgctca
    19741 tggcgtaacg actttcaaag cttatgcatt ctatgctcct gctgctttga tgattttctc
    19801 cgctattatt tttgcttgga agattacatt gacagagaaa aaacatgcac aaatcgttga
    19861 gaaattggaa aacaaattgg ctccagctga tacaatggaa gatgaacttc acgatgcagt
    19921 agttccttcc cattaagaaa ggatcttgaa aatgaagatt acagaaaaag attttggcca
    19981 aggttatcac ttgataacct tggagaacaa aaacaagcta gcactttcta tctctgattt
    20041 aggtgctaga atcgtcagtt taaaatcaaa tgatcgagaa ttagttttgg gatttgacac
    20101 cgctgaagaa tatatcgaaa aagatccgta tatcggtgct tctatcggtc gcaccgcagg
    20161 gagaatcgaa aatggccgct tttctctcaa tggaaaaact taccaattag ccacagatcc
    20221 aaaaactgga cataatctgc atggtggtgc tcctggattt gaattaaaaa aatggtctta
    20281 tgtcattttg aatggcgaaa atgaagcttc tgtcattttt actactacaa gtcccgacgg
    20341 agaacatggt tttccaggta caatggatgt ggaaatccgc tatactttga caaaagataa
    20401 tatctggcga gtgacctctc gcggcaccag tgaccaagat actttattca atccgacaaa
    20461 tcatgtttac ttcaacttga cgggagatgc ttctcagtca atcgatcaac atgagctttg
    20521 gctcaatagc gaagcttatg ctcctttgcg aacagatagt attcctatag gggtaaaaga
    20581 aaatgctgca ggaagtgctt tcgattttca aatacctaaa aaattagcgt ccgtttttgc
    20641 tagtgatttg gatcaaaaaa atcttgttga cggaatcgat catccatttt tcttaaaaga
    20701 aaccggcttg ggtaaagaag ccgctcgctt gactagcccc gataaaagaa tccaagtaga
    20761 tattgctaca gatgcttcta gtgtggttat tttcactgca aatttcggca cagaaacacc
    20821 agaaatgcgc aaccgaaaac tggcacatca cggtggcatc acatttgaga ctcaaacagc
    20881 tccaggtgca gagcgcttct cagcatttgg ttcgattcat ttaaaagccg gatcagtatt
    20941 tgaaacagta acagaattca aaatcaaaac aagaaaggaa taactcatca tggaaatcaa
    21001 aagaagctta aacacaaaat ttgccgaaac attcggacct aaaaaaacta cacaatactt
    21061 ctcaccagga cgcatcaatt tgattggtga acacacagat tacaatggag gccatgtctt
    21121 ccccgcttcc atcacttatg gaacgcaagg tgtagcagca cctcgagacg ataataaaat
    21181 attagtttat tccacaaact ttgacgatat cggtgtcatt agttttactt tagatgagct
    21241 agaatatgat aaaaaagcaa actgggcaaa ttacgtaaaa ggaatggtcc ttaaattaaa
    21301 agaagctgga cactcaatcg atcatgggtt tgagttatta gtggaaggaa caatccctaa
    21361 tggtgcagga ctttccagta gcgcttcatt agaattatta gtaggtgttg tattagaaga
    21421 tctgtttgat ttaaaaacag atcgcttgga actagtccaa acaggtaaaa aagtagaaaa
    21481 tgaattcatc ggtgtcaatt caggtatcat ggatcagttt gccatcggct tcggtgagct
    21541 agatcatgca atcttattag atacaaatac gctgaaatac gaaatggttc cagtgaaact
    21601 agatggttat gcaatcgtca tcatgaatac gaataagcgg cgggaattgg cagattcaaa
    21661 atacaatgaa cgccgtagcg aatgcgaaga agccttggca cgtttgcaaa aaactttgcc
    21721 tatctcttct ttaggagact tagatgaaga agaatttgaa tcaactattg accaaatcgg
    21781 cgatgataca ttgatacgca gagctcgcca tgccgtttct gaaaatcagc ggactttgaa
    21841 ggcaaaagct gaattagaag ctgggaactt agaagcattt ggtcaactgt taaatgattc
    21901 tcaccactct cttcgctatg attatgaagt aactgggatc gaattagata cactagtaga
    21961 tgctgctcaa aaacaagaag gtgtcttagg tgcacgaatg acaggagctg gatttggtgg
    22021 ctgtgcgatt gctcttgtca aagaagaaaa tatacctgcc ttcaaaaaca atgtctatga
    22081 tgaatacatg aaagttgtcg gctatgctcc ggaattttat gttgcacaca ttggaaatgg
    22141 gacaacaaag atcgatccag aagctgttca tgtttgataa aaaaatcaac gatctcagct
    22201 aaaaacaaat agataaaaat aacctctcag caatttccaa atgtgagcct tttgctcgta
    22261 tttgaaaatt gctgtttttt attgacacgg aaagagaacg tgtgttctaa ttgtgttgaa
    22321 gaggtgattg ttatgtgggc gaatcaaaat ccggtatttg tttatgaaaa agaaccttca
    22381 agagatattt tatgtattga ctgcaaatct ttttacgcct ccgtagagtg cgttgaaaag
    22441 gatcttgatc cccttacaac taaattagta gtcatgtcct atccgtccga ttcgacagaa
    22501 acacggggta gcggattaat cttggcttcc agtcctgcag caaaaaaagc ttacggcatc
    22561 accaatatca gccgtgccag agatcttccc ttcccctatc caagtgattt atatattgtt
    22621 gccccaagga tggcctatta tatggaaaag aacagagaaa tcaattctat ctataaaaaa
    22681 tatgcagacg aagcgaacca tcatgtctat tccgtcgatg aaagcttcct tgatgtaaca
    22741 aatagcatgg cactctttgg taaaacaaat gcgtacgaca tggctaaact gatccataaa
    22801 gatgtgtttg agcagaccgg aatctacacg actataggaa ttggcgataa cccgctactt
    22861 gctaaactag ccttagacaa tggctcaaaa gacggaaagc aaatgtttgc tgaatggcgt
    22921 tatgaagatg taccagaaaa gttatggaaa atctcagata tcactgactt ttggggaatc
    22981 ggcaaacgaa cagcaaaacg tctgaaacaa atgggtatac attctgttta tgatttagct
    23041 cacgcggatt attatcactt gaaaagcaag ctaggggtca tcggtactca gctttatgcc
    23101 catgcttggg gcatcgatcg aagttttttg ggacaagaat atacaccaaa atcaaaaagt
    23161 atcggaaata gtcaaatcct agatagagat tatacaagac gagaagaaat cgagatcgtt
    23221 atcaaagaaa tggccgacca agtcggcact cgcttgagac gatctgcagc aaaaacacaa
    23281 gtagtcagct tatgggtagg atactcttta ggctatcttg atccaaatgg caagaccggg
    23341 tttcaccagc aaatgaaaat cgaagcgaca aatgctagca gagatctagc agatgcttta
    23401 ttgaccattt tccaccagca ttaccactac caggatattc ggcgtgtagg cgtgaactgt
    23461 tccgacctcg tatacgcgac aggtttacag cttaaccttt ttgaagatcc tgaaaagcag
    23521 ataaatgaag cgaaagttga ttttgttgtc gatacgatta gaaaaaaata cggctttcaa
    23581 tcaatcatcc atgcgcatag tctcttgcaa ggaggacgcg ccatcgcacg tagttctctc
    23641 gttggcgggc atgcaggtgg tatgagtgga ttagaaggtg gaaaagatga gacggacagc
    23701 aaaaaaattc attgactata acgagtatcg agatcggcca tttggattaa aatgggggac
    23761 tgcttttgcg atggaagaac tagtcaacgg tatcaaaaaa atgaagaaga agcacgcaaa
    23821 cagcctcttc ctaaacaaca aatgacattg caagaaatcg atagtatact gacagaagcc
    23881 tttttatctc gtaaagcagt aatcattcag ctcaatttaa aagatgaatt tggaagactc
    23941 ttggatgagg tcgaagggca cttcattggt gaagcctatg aagattactt tatgattgac
    24001 catcagccga tattgtggga agacgtacgg tatattgagt taaaggaaac aaaaaaatgg
    24061 tttgtgacat gagaggttgt gacagaagtg atcaacttca aaaaataaga aaggattttt
    24121 cgaaaattgc ttcttaaatt tttgtggaat tttggcttat ttttcgaaga agcaacttct
    24181 ggaacaacgt atattagata tcagaggttg tgaaaaagtc gcttagtttt gagtaacaag
    24241 ccaaggcgct gatttcacaa cctctgtcta tctatccatc tattcggtaa gattcatgca
    24301 tgacgtcttc tttatttagt atgtagagcc ctttttcttc tgaccattca acataaatca
    24361 gctgttttac atctgcatag ccttctttct tcaagttctc cataagccat gcttcagtca
    24421 attgattgga ctgaagcact ttatgctgaa tttgcccttc atctacaagc aggatcgata
    24481 aagctttgtc ttcatctgat tttttcaata cactcatttg accggcattc tctaggataa
    24541 catgtttggc attttcaaga aaaaagcatt cttgctgtct taagattgct cgcaactgct
    24601 ccatctcgat atggttattt gtcaactctg tcatgttgat gacgccgtct ttgattagaa
    24661 cagatggctc gcctttgacc caacgattga ccttttcatt tttttggacg atacgttcga
    24721 taccataaat cattactgcc caaagcgcaa tggcaaatag gacatgccct acatggacat
    24781 tgtcatcata ggttgattct tctaagatcc cacctaaaac aagcgtatag actaaatcaa
    24841 acggtgtgat ttctgacatg gatttcttcc caagcaaacg taccactaat aataaaccga
    24901 tcaacccgaa caccagtttc attgtaattg aaaaaatcat tttttctccc cctaactatc
    24961 tgttaattaa attatatatg ctttctcacg aacacgcatg gaatatacaa ggaagaaatg
    25021 tatcctttta ctaaaaaaag gactgtgaca ctgtagtgac ccccaaaagt tagacttttt
    25081 tggagtggag aaatccactc ctttttttta tgctctaaaa tgatattttt acacaaccgt
    25141 tacggttgtt ttacgaaatt ggacgagact ttgccagttt aatttctgtt ttatccgttc
    25201 attattgtag taatagatat agctatcgat ggctgatttt aattcctcga aacagttata
    25261 aactttcccg tgaaaaatct cttgttttaa taagccaaaa aaattctcca taagtgaatt
    25321 atctaagcag ttccctttcc gagacatgct ttgaaagatt ttgtactcct tcaatttgtt
    25381 tctataagct ttcatttgat acgcccaacc ttgatctgag tgaaacgtac gacgataggg
    25441 acaatcgtta gtggtctgga tagcttcctc caaaccttcc attaccgcta atgcattggg
    25501 cttttcagag atacgatagg ataaaatctc actattgaac atatccataa aaggatctag
    25561 atacaatttc ttttgacgga taatgccttt ggcatccact tcatggtatt taaattcagt
    25621 tgtatccgtc gtgattttct gatggcagat actggtgtag aaacgacgat ggatccgatt
    25681 tttggctact gctccaactt ttcctcgata agaattgtag cgacgtgatt tacgcgtgta
    25741 tgccgttact tttattccta gcttcttgat caagcgctga actttctttt tattgataga
    25801 gaaaccgcgg tttcttagtt cattggtcat ccgtaaacag ccataatcct tgtgcttctc
    25861 ccgaatttta agcatttccg cttcaatctc ttgatctgga tttttacggt ccaatcgcct
    25921 ttgccatcca aataatcatg aacgatcttt aatttaagtt caaaagtata tttaaccata
    25981 aaaaataccg acctccaaaa gttagatttt ttggtctaac ttttgggggt cggtacacaa
    26041 atcgtgtcac agtccctttt ttgaaaataa acggtgttca aaagcttgca tctgcggtaa
    26101 taagtccagc caagttaaaa acataagaag ctgtttttac ttggctgttc ttattacttg
    26161 atgcaaggca gctttttcac aacctctttt caaatatttc gttttcttat tctacaaatg
    26221 gttcttctcc taacgcttgt tgagcggcta gattcaacat gctccattgt cggtcaaagc
    26281 ctggctggaa gaagaagtca gcttctgcta gttcttctaa agtcagtttg ttttggatcg
    26341 ctagtgccaa tacatttcct tgacctgtaa catcataggt agataatact gctcctccta
    26401 gcaattgatg ggtcattgga tccgagaata attggatgga cacttttgga tttccttgtt
    26461 cttctggtac atattttggt cgtaacgtat cttcataata agacactcgt acatctactc
    26521 ctgcttttgc tgctgtaaag ctattcaatc cgcttgctgc aaaatgatag tcaaagacac
    26581 ttaatgcaga ggaacctacg actccgccga acggtttgtt tggtacttct tcaaaaagat
    26641 gttttactac ataacgtgct tctctacgtg caacagtcgc taaagcgatc ggcatttttt
    26701 tgcgtgctgg gatagaataa gcaagtgtag catctcctac tgcatacaca tctggaagat
    26761 tcgtttgcaa gtattcattt gtttggatcc agccacgttc atctaagtcg acgatccctt
    26821 ttaaccattc tgtatttgcc ttcacaccgg cagcttgaat gactagatct gctgggattt
    26881 ctttttcact tgttttgatt gcctcaactt ttccgttacc agtaaaagct tcgatttttg
    26941 catttgtcaa aacttcaata ccgttttcat ttaggtgttg ttctaaaata tctgtcatct
    27001 cagcatctaa ataagtgcct aaaggtctat cgatcacatc aagcaatacg acttctttcc
    27061 cagcttttcg gcttgcttct gctgcttcga tcccaatgta acccgcacct acgacagcga
    27121 tttttttaat agccggatca tttaattttt ctttgatttt ggttgcccaa ttgtatccac
    27181 gcatcaagta gacattttct agatctgctc ctggtactgg cagattgttt ggtttgacac
    27241 cagaactcaa aatcaatttg tcataaggat attcttttgt ttcgttatct gatgcgctag
    27301 taaccgttac tgttttttta tcggcatcga tcgtttttac ttcgtgatta tttaaaatat
    27361 gaacattgga ttgcggaaag ttttctggtc tgaaattacg tacatcattt acatctgtta
    27421 ccttgtcttc taaatacagc tccataccac atgacatgaa ggaaatatag tctcctgctt
    27481 caaatagcgt gatatctaca ttttcaccgt atcgtgtcaa tagttccaag atcgattgat
    27541 gccctccatg agatgcacct acaatgacaa ctttgatttt ttccattgat gaaacctcct
    27601 tgaatattct tttaaaatca ttctaaacaa tttaaactta acattacatt agttatgaat
    27661 caaaagaaac gcgttcattt gaactaaatt taaaaaacaa tcgtctcctt gcagaatata
    27721 ccgcaaaatt aacgattgtt tttttgataa aatctatgaa tcactgttct gttaaaaagt
    27781 ctttgatccg tttgcaggcc tcatgtaatt tttccatgct gctagcataa gaaatccgga
    27841 tataaccttc tccttctggg ccaaatgcaa ttcctgggat acacgcaact tttgcctgtt
    27901 ccgctaattc tacacaaaac tgccaagagt cagtttgaat ggcagctggg agtttgcaaa
    27961 acaagtaaaa tgcaccgttt ggctgggtca cttcaaatcc taaaggcgcc aattgctgga
    28021 ccagatagtc tcttcgtgtt tgatattgct ctttcatatt ctcgctatct ttcaccccat
    28081 ttattagcgc ttcagccgca gctttttgcg acatcgttgt agcggcagtc accagatatt
    28141 gatggacttt aattagttcg tcaataaggg ctttttgagc aaaaataaag cccactcgcc
    28201 aaccagtcat cgcatgtgac ttggataacc cgcttatcac gattgtttgt tctggaagat
    28261 aagtagctat ggacatatgc gttccactat aagtcaattc agcatatact tcatcactta
    28321 taacaaatac cggatatttt tttaaaacct cagcgattgc tttcaattgt tttgcagaca
    28381 atgtcgtccc agtaggattg ttaggatagt ttaaaatgac tgctttgaca gctgatccat
    28441 attgttcaaa tgctcgttca aattgttccg gctgacagac aaaccctgtg tcagaagtat
    28501 ctatcgggat caattcagca ccagctagtt ccactaatgg ctgatatcct gaataagcag
    28561 gcgctggaat aagaaccttg tctccttctt ccaaaacaga taacaacgca gaggcaatcg
    28621 cttccgttgc accaactgtc gtcaaaactt ccgtttgcgg atcataagtt aatccataac
    28681 gctgttgctg aaatatacaa gccgcttccc gcagttcctc taatcctctc attccggtat
    28741 agtgagaaaa gtcttcttca atcgctgcta ttcctgcttg cttgacatgt tcaggagttg
    28801 gaaaatccgg ttctcccagg gtgagtttga tcacatctgg tatcgacgat atttgctgat
    28861 cgaattgtcg tatttttgat acttctattc tagaaagcct aggactaaat cgattggata
    28921 aattcatcat tatttactcg ctcctctttt gaactgctat cgatttttac aagaagattt
    28981 tctgtaaaaa gaatcgtttt gtaccattct acaccatttt ctaaaacatc catatcaaaa
    29041 tcgaacgtcg gatcatgtaa agcaggggta tcaccgacac ctaaaaagaa aaatacacat
    29101 ggatattgtt gcgtatatat gccaaaatct tcggcttgaa gaactggagc atctaattca
    29161 tgtagtttgt ttgaatctaa cagtgctgca tataagcctc tatggttgat tacagctgga
    29221 tagccgtcat tatagcgaaa agaaatagta gctgtagagt gaaactgttc tgctaaatgg
    29281 tctaatcccc tcttcaaata attttgcata tctgaactgt aagaacggat acttccggat
    29341 acaataactt ctccagctaa aacatttcgg atcgttccac cttggatttg gccaaatttc
    29401 attagatgat tccactctgc cggtaattgc cggtcaaaat cataaacatt cttcaaaaat
    29461 cgtacagctg cctccagact atcgattcct ttttcactag aagcaatatg tgcagactgg
    29521 cctttaatga taatgtctgt ttcactgctt tgtgccatca aaggtcctgg tcgagagaaa
    29581 acttctccct tagctagtcc aggccataga tgaaagccaa atattgcttg tacttcatat
    29641 ttatccaaca atcctgactg aataacgctt tgtgcgccac cggaaatttc ttctgatggc
    29701 tgatagatca gtactacatt ataaataaga tcctcaatgt gtttagttat aaagtcagtc
    29761 aaccctaaaa gcatcgccat atgtccgtca tgaccacatg catgcatata accttcatgc
    29821 ttagaagcaa aagagagatt cgtttcttct ttgactggca gtgcatcgat atctgttcga
    29881 aaagcaatcg tttcttcttg ctgattatca aaataaagga gtagtcctgt ttcgccgatt
    29941 tcatggataa cggcctcgct gttttttact tgttcatata aatatttttt tgtcttgaat
    30001 tcatgaaacc cgatttcagg aatttgatgg agtgccattc gatattcttt cagcatccgt
    30061 attcaccatc ccttcataga tacccttcac tactgttcca tattgattat tcggtacacc
    30121 gatgatcaga ttcaactcct gtgctccttg tgataagatc gatgtgcgaa tttctaattt
    30181 gttcaatatc gataacactt tcccagataa tccaatcaat tctttatgcg gacccccaac
    30241 gacagagatc aaagctaagt cttcgatcac gacgatttct tccacgccaa gtgtttcttt
    30301 taattctttc gtgatgagaa ataacttatc ggcaatcgct tctgctgaga cgatcactcc
    30361 gatattgtcg atccctgaag gaatatgttc gattgatatc tcatgtttag caaaaatgct
    30421 cattgctttc cagataaacc cgatttcatc ggacatatga cgtttgaata aagtgatgga
    30481 aagaaaatcc ttgcgtccag ctattcctgt cagtccattt tccttttcta tttcgtgatt
    30541 cgatattttt gtcccttgag cgaaaggatc attggtattt tttatttgga tggggatatc
    30601 agcctcttga actgggaaaa cagctgcttc atgaagaacg ttagccccca tataagccat
    30661 ctctctcagt tctctaaaag agatttcctc gatgatttta ggatgatcga tgattcgcgg
    30721 atcagccatc atgattcctg aaacatccgt ccaattctca taactttccg cttgcaacat
    30781 cttcgccagt atcgcgccgg taatgtcgct tcccccacgg cccaataatt tttcttttcc
    30841 tgcagggttc gccccgtaaa accctggaac aaccattttc ggatatcttt taaatgcttt
    30901 tgtgatttcc tgtgctgttt tttcctgatc gattttccca tcatagtcaa agaaaatcag
    30961 gtcttttgcg tcaataaact ggtaaccaag atactcagcc atcagttgag cagtcagata
    31021 ttcacctcta cttactaaat aatcttcagt tatcttttcg tcttccagtt gtttctgtat
    31081 gcgtgctagt tcatcttcaa taggtaactg cagggcaaga acatctctta cttgaatgaa
    31141 acgatcacaa atccttttcc aaaggggtgt ccaatcaaca tgatgctgaa ggtaagcata
    31201 aatcaaataa agtaagtctg ttactttgtc atcatctgac gtacgtttgc ctaaagcaga
    31261 aacaacgatc acttggcgat tgggatctga aagaacaatt gtacggactt ttttgaattg
    31321 ctcttcatga gacatcgatg ttccgccgaa tttcgctact ttcagcgtat tactcatctt
    31381 gccacctccg ctattttctg cattaaagct gcagcaatct gtacggcatt cgcagcggct
    31441 cctttgcgta tgttatcggc agtcgtatag aacaacaatc cgttctctaa agaagtgtct
    31501 tttctgatcc tcccaacata aaccatatct gttcctctag caagaatgct cgtcggatat
    31561 ttatgtgctg ctagatcatc ttctaattga atccctggaa actggctgag acactctcta
    31621 atttcttccg tcgtaaactc tttttgcagt tgaactgcca cagagactcc atgtccattt
    31681 tcgattggca cacgtacgca ggttgctgat actggcaaag caggctgatg cagaatctta
    31741 cgggtctcat ttatcatttt ctgttcttct tttgtatacc cattttccaa aggctgatcg
    31801 atttccggaa tcaccgtttg gctaatatta taaggataca aaactggttc ctcgtcattt
    31861 tgcgtacgat gaagatcttc aatgcctttt tgcccggaac cagaaactgc ttgataggtc
    31921 gaataattga ctcgctggat accaaaggct tcttgtaaag ctttaagcgg aagtaccgct
    31981 tgaatggttg aacaatttgg atttgcaatc agccgattca atgtatagtc ttccagattg
    32041 acctctggaa cgattaatgg aatatccgaa tcttcccgcc atgctgagga attatctatg
    32101 acaaatagtc cctgacttcg tgcgattggc gcaaactctt tggatacaga agcacctgca
    32161 gaaaatagcg ctaaatcata tccttcaaat gaagtttctg tcaattcctg tacagtgtgt
    32221 ttctttttct tgaatacaca aactttaccg gctgaacgtt ttgaagctaa taatttcaat
    32281 cgtcctactg gaaaatcata ttcttctaac actttgagca tcgtttggcc gactaatccg
    32341 gttgccccca caatacaggt atctatttcg cgcatttttc tccatctcct ctataattcg
    32401 cgtaacgcag caatcaatgc tgtattttct tttgtctgat catcacttat ttttaataca
    32461 cgtgcaggta ttccaccgac aacagtttct gctgccacat cttctaaaac cactgctcct
    32521 gctgccacga ctgcatcttt tccgatatgg acaccttcaa caatcactgc attcgcacct
    32581 accagtacgc cgtcttctac gataaccggt ttggccgatg ctggttcgat cacacctgct
    32641 aagacagctc ctgcaccaat atggcagttt ttgcccactg tcgctcgtcc acctaagaca
    32701 gcacccatat caatcatcgt gttttcaccg attactgcac caatattgat aatcgctccc
    32761 atcatgatca cggcattgtt gccgattgac acttgatctc tgataatagc acctggttcg
    32821 atacgagcat taattttttt aatatctagc aaaggaactg cgctgtatct tgcagcagtt
    32881 tcgatttcga tttcaatgat tttttctgat tcagcttcta aaaccggagc aatcgtctca
    32941 tagtcaccaa aaacaacgaa gctgcttcct tcaccaaaaa ctttactttc tttaaattcg
    33001 attggctcgg ttacattcag atagactttc acaggcgtct ttttagatgc cgtttgaatg
    33061 tagcggatga tttcttgagc ttccacgttt tttacacccc tttgtccatt aataaatctt
    33121 ctaatttgta ataacctggt gactgatctt tcaaccagtc cgctgcttct actgcgcctg
    33181 cagcaaagat tcgattagaa aaagattcat gtttgatcgt aaatatttca tcagtagcag
    33241 caaacaatac atcatgttca ccaggtaaag aacctgcacg aatactgtgt acaccaattt
    33301 ggttttcttc tctttttttc ccttgccagt tgtatacggg ctgcagcttt tgcacttctt
    33361 ggattgtttg aagcagcata tttgcagtac cagatggtgc atctttttta cgactatgat
    33421 gtttttcaat cagttcgatc tgccagcctt gcaacattgc agctgcttgc ttgattagtt
    33481 gattcatcac catgatgccg aacgaaaaat tagcactata catcacaggt acatgtttgg
    33541 catgttcttt tatttcttgg aactgtgatt gtgtataacc tgtcgtgcca atgactaacg
    33601 gaagttgata tgataagcta tacgaaagga ttttctctaa attatctgga tgagaaaaat
    33661 caataagcag ttctggcagt tccgtaaaag caagcgtagt tgcttcttta ggtgccgtcc
    33721 gtaaaagaag gaccgtatct cctctttctt gtgcaacttc ttcgactcta tttcccatct
    33781 gtccactgcc aatcagtccg attttcattt ttcaaccgtc ctttctttta acaaaagctg
    33841 agctaattgt ttctttttct cttttgaaag agaaactaaa ggcaggcgta gaggtccgga
    33901 aggtaagtct aataatgaca tggctgcttt gacaggaata ggattggtct cactgaacaa
    33961 ggcatggatc agttcaagtg catttaattg cttttctttt gcttgctgcc atcttccgtc
    34021 ctgcgtatct tttactaatt catggactat tttaggttgg atattcgccc atacacttat
    34081 tacaccgctt cctcctacac tcattactgg taggatcaaa tcatcatttc cactgtaaag
    34141 gaagaattct tctccaatca accgagcggc atccatcaca taagccatat ctcctgaggc
    34201 ttctttcaaa ccaatgatat taggatgttc tgctaaattt actaatacat ggattggaat
    34261 cgacatgcct gttctagaag gaacattata caaaataagc ggaatcggtg aggcttctgc
    34321 aattgctgta aaatgagcag ctagtcctgc atcacttgtt ttgttgtagt aaggggtgat
    34381 gaccaaaagt gcgtctgccc ccaaagaagc aaaatgcttc gctttttcaa tcgtttcttt
    34441 cgtattattc gttccagctc ctgcaatcac cggcacacgg ccagccactt tctttactgt
    34501 cagttgaagg atctgctcct cctcagattg tgtgagcgta gaagattctc ctgttgtacc
    34561 taaaactaat aatccatctg tttgttcatc taaatggaat tggatcaatt tttccaaacc
    34621 agcataatct actgatccct cttcattcat cggcgtgatc agcgccacga tcgaaccttt
    34681 tatcatcttc attcctccaa tattcttgtc cattcatgaa ctgctgggcc agccatttgt
    34741 atcgcatcct caccagagat catcaagtct ccttgttcca agtgaacaac tacctgatct
    34801 gctgaaattt tcccagtttc cttagcaacc acataagagg cacagcaacc tgtaccgcaa
    34861 gcaagtgtcc aacctactcc tctttcatag gtacggacga tcaattcttg ttcattgact
    34921 acttctacaa agttgacatt ggttttttct ttgaacaaag gatgatgaca gatcagttca
    34981 cctctttttc tccagacttc ctcacgcgca ttttcaacaa aaacaacggt atgaatcgtt
    35041 cctaaaaata aactagtgat cgttactttt tcaccattga tctctatttc ctggtttttt
    35101 attggataag tttgattagc tttgattttt tccggagaat catctggcac tcccatatct
    35161 acgctgcaat aaaaaggtga gggatccaac accgtaattt ttcttgtgcc tgctaatgtc
    35221 tctacgttga attcctgttc attcatcatg ttctgatcat ttacgtatcg agcaaaacag
    35281 cgaatgccat ttccgcacat cggcgcgcgg ctgccatctt tgttgtaata gatcatttcc
    35341 aacggatcga tttttacggc gatcaatccg tctatatcat atttttcttt tgtgcataaa
    35401 gaagcggcta attgactata atctgtgtct tctgcgtaat ctaataagat aaaatcattt
    35461 ccgcagccat tatatttatg aaggatcata ggaaacttcc ccccttagta gatcagaaaa
    35521 tgcttgtctg cgaacaatca gtcttgattg gccattattg acaaaaacaa ctgctggtcg
    35581 tgtcgctcga ttgtagttgc tgctcatcga gtatccataa gctcccgtgg aataaacagc
    35641 taaaagatca cccgattctg ctttcggcaa ataagcttct ttaattacca catcgcctga
    35701 ttcacacatt tttcctgcaa tcgtcacttt ctctgttttt tcttccgaca gttttgctgc
    35761 taaatcacaa tcgtattctg cctgatacag agctggacgg atattatctg tcatcccgcc
    35821 atctacaaag taatattttt tatgtggtgt ctttttgatg aaaccaatcg tgtatagtgt
    35881 tgtaccagct tctccaacaa tacttctacc cggttcgatc agtaattgac gaatggtcag
    35941 ttttcgtttt tccaaagctt cttccgtata ttcaatcagt ttttttagtg cctcttcgac
    36001 tgggatcggc tgatcatttt gtgtataacg aatcccaaac cctccgccaa gattcaagga
    36061 aagaggttgg tcaaaatcgg ttaagtaatt cgtcaatttg tcgatttcag ctaaccaagc
    36121 agtaacatca aaaatttgtg acccgatatg agcatgaaat ccttctaact ctagatagct
    36181 gctttctttt atcaactgaa gggcttgttg gcactcttta ctttcatagc tcatgccgaa
    36241 ttttgaatca atatgcgcag tgacgatata ttcatgagta tgtgcttcta ctccgacatt
    36301 caaccgaagc atgatacaga ttttttttaa atagcgttgg cttaattctg ctaataattc
    36361 aacttccatc aaattatcgg caacaatatg caacaaatca ttttcaagtg catagatcag
    36421 ttcctctggc gtcttgttgt taccatggaa gtagatagta tctctaggaa aatcagcttg
    36481 caaagcggta tagatttccc caccactgac aacatctagc ccgaatccat attcacgaac
    36541 taaatgcagc atctcaatcg tttggaatgc tttagaggcg taaagcactt ttgtatcaaa
    36601 acgtttcgat acaaagcctc gcttgaatga cagcatcgtt tgtctcatct tttcttcatc
    36661 atacacatac agaggtgtct tatacttttc tgccaatgtg cttgctgtga ctccgccaat
    36721 tatcaattct gtcatttttt cattcctctt ttcacttttt ttccgttttt attggaattt
    36781 catttgataa agatttgaat tttattggaa taatattaaa caaaattttc tgaattgtct
    36841 agtatatttc gaaatatttt tttaaaaata agaataaaaa tggttataaa aacaaaatac
    36901 ccgaactatt agaagctatt tatacataaa aacataaatt caacactatt tagtgatgaa
    36961 aaaatatttt cgcttcaata tagttcggaa tagttcggat attttcaatt ttatgaatca
    37021 tttcaatttc ttcataaata agtgcagttt tttctttctc tagcttttgc cattcatctt
    37081 tcaaaatata aataaaatca aatacttttt tatttttcaa tttgctgatt ccacaaaaaa
    37141 cctcttgaaa ggcagatccg atgatctgcc tttcaagagg tcaagctctg ttttcaaatt
    37201 cttatcaatc cgttagcgaa ttattttgac gcacgtttta cataagaacc ttctgctgta
    37261 ttgatttcca acaattcatc tgtttcgatg aagtcaggaa cattgactac taagccagtt
    37321 tccattgtcg ctggcttacc tgaaccagtg actgttgcac ctttgatgga aggttgtgtt
    37381 tccacaacac gtaatacgac agttgttggt aattgaacgc cgatgacttc gctaccgaaa
    37441 aattggattt ttacttccat gttttctagg atatatttca tttcttcttc tactgtttct
    37501 acaggaattt catattgctc atatgtttcc aaatccatga agaaagctgt atcatccatc
    37561 gtgtacaaat attgtacagg ttttgtgtcg atatgtgctt tttcaaattt ttcttctggt
    37621 ctgaacgttg tgtcgtatgt tgcacctgaa cggacatctt tcagtttcat acgcataact
    37681 gtatttcctt taccaggttt atggtggctt gcatccagaa ctttaatcag tttgccgtct
    37741 tgtacgaaag tcataccggc tcttaaatca cttgctgaga tcattatttt tgctccttct
    37801 tttctttatc ataatcaact ttattgtatc agacaaccgg ccagaaaact agagtattct
    37861 ctatctttta aggtctcatg cctatttgtc agaaaaataa acacgggtaa acgatgctat
    37921 cgaaatattt ttttctttca agcctttgac ttttattttt tttcatgcta tcgttaataa
    37981 aaattttact tggagggata cacatgacag tcagcaacca aaaacaattg aatcgttgct
    38041 gttgtatggt gcataaaagc agcatactat ttgtcatgtc tattaattgc ccttcataga
    38101 atgagtacca ggtaacttat ctttttatct actcaatttt tctctatgtc tttcaaggag
    38161 ctgatttaat agtcagctcc tttttttatt atcttttttt aggaggccca catgattatc
    38221 tcgacaatta cagaagctat tggttccaca ccgctttatc gctttgacaa tcagcactat
    38281 tctatgccta aaggttctgc tatttatgca aaactagaat atttaaatcc tggaggaagt
    38341 atcaaagata gattgggcag ttatttgatc aaagaaggat ttgcccaagg aaaaatcaat
    38401 gaaaaaacga cgatcatcga accaactgcc ggaaatacag gaattgggat cgctctggcc
    38461 gcactcacat acaaattaag aacggttttt gttgttccag agaagtttag cttagaaaaa
    38521 caacaattga tgaaagcatt gggagcaaag atcatccatt ctcctagtga gcaaggaatc
    38581 atcggtgcca tcagcaaaag taaaaaactt gcagaggaga tatcaaacag ctatctgcct
    38641 cttcaatttg aaaataaaga taatcctgct gcttactatc atacgttagg gccagaaatc
    38701 tttcatgaaa tcaaagaaaa tatccatagt tttgtagcag gaattgggag tggtggaacc
    38761 tttgctggaa cttctacctt tttgaaagaa aaatatcccg acattcgaat aatcggtgta
    38821 gaaccagagg gctctgtgtt aaatggtggt gatccagccc ctcacgaaat tgagggtatc
    38881 ggtgtagaat tcattccgcc gtttctttct cccctttcaa tcaatcagat cgagacaatc
    38941 tctgatgtag aagggtttaa ctatactagg cagttagcac gagaacaagg actattagtt
    39001 ggaagttcga gtggtgcggc ttttgcagca gcattaagag aaattcgtcg tttaccacct
    39061 ggtcatcgtg tcgttacgat ttttccagac gcagcagacc gctatttatc aaaaaacatt
    39121 tacttatagg aggaaagaaa catgcacatt caaacaaaat tgatccacgg aggcatcagt
    39181 gaagatccca caacaggagc tgtcagtgta cctatttatc aaacatccac ttatcggcaa
    39241 gatggcgtcg gccagcctaa acaatatgaa tattcaagat ctggtaatcc tactcgtttt
    39301 gcattggaag aactgattgc tgatttggaa ggcggtgttc gaggattcgc tttttcttct
    39361 ggtctttctg ggattcatgc cgttttttct ctttttcaag ctggcgatca tatcttatta
    39421 ggagatgatg tctatggagg aacattccgt ctatttgaca aagttcttac taaaaatggt
    39481 ctcgagtaca cgatcataga tacgagtaat cttgataaaa tagaacaatc catcaaaccc
    39541 aatacaaaag cactttatct tgaaacacct agcaatccgc ttctaaagat tactgattta
    39601 gaaaaaagtg ccactctggc tcatcaacat ggattgatag ttattgctga caatacattt
    39661 gctactcctt attttcaaag acctttagat ctcggttctg atatcgttgt ccatagcggt
    39721 accaaatatc taggcggaca cagcgatgta gtagctggtt tagtgacttc taaccataaa
    39781 gatctagccg atcagatcgg attttaccaa aatgctatcg gagccgtact tggtccccaa
    39841 gatagctggt tacttcagcg cggaatcaag acactaagtg ttcgtatgga ggaacatcaa
    39901 aaaaatgctt ttgtggtagc tgattttcta ttttctcatc cagcagtaga aaaggtctac
    39961 tatccaggat tacccgatca tgaactccat ggagttgcta agcagcagat gagcggcttt
    40021 agcggaatga tttcttttac tttaaaaaat gaagaatctg ctattccatt tgttgaatca
    40081 ctccaactat ttactttagc agaaagttta ggtggcgtag aaagtttagt ggaaattcct
    40141 tctgtcatga ctcatgcgtc tattccaaaa gaaaaacgag aagaggctgg cataaaggac
    40201 ggcttgatcc gtctttctgt aggaattgag tatggtcagg atctcataaa cgatttagct
    40261 caggcatttg acagaatcaa gaactagaag tcccaataaa cgacttagca gaaaaatcta
    40321 aaaaatattt cagattgcta caccttggaa acgataagtg ttagaatcaa gtagaaagac
    40381 gtttttgtaa atttcactaa ataattcttt agtgaaaagc atcaaaacga atgaacaaac
    40441 agataggagt cttacaaatg agaatgaatg tcgaaagttt taatcttgac catacaaaag
    40501 tcaaagcacc ttatgtacgt gtagctgatc gaaaaacggg tgcgcatggc gatgtcatca
    40561 ttaaatacga cgtccgcttt aaacaaccaa ataaagaaca catggacatg ccaagtctac
    40621 attcacttga gcacttgact gccgaactaa tccgcaatca cgcagattac atcgtagact
    40681 ggtctccaat gggatgccaa acaggctttt acttgactgt attgaatcat gaaagctacg
    40741 aagacatttt agatgttctt gaagcaacaa tgaaagatgt tcttgaagct actgaagtac
    40801 ctgcaagcaa tgaaacacaa tgtggctggg ctgccagcca tacactagaa ggtgcacaag
    40861 ctttggctcg tgaattttta gcaaaacgcg atgaatggtc tgaagtagaa gcatagtttc
    40921 taaaagaacg taaagatgag aagcaatata gctatcttat cttcgtattt tattaaatat
    40981 ttattgtctg aaaagagttc taaacgggaa aacaaatagc tagttttcag tttagcgctc
    41041 tttttattat ataaaataga aaggagaaaa ctttatgtct atttataatt ttgaaactac
    41101 tttagaagac ggcactgtct attcattgaa aaaatatgca ggcaaaccga taatcattgt
    41161 taacactgca acaaaatgcg gtctagcacc tcaatttaaa caattagaag aactttacca
    41221 agcttatcag acacaaggtc tggttatctt aggctttcct tccaatcaat ttaaacaaga
    41281 gctagattca gcgactgaag cagcagaagc ttgtaaaacc acttatggcg ttaccttccc
    41341 tatgcatcaa ttgattgacg taaatggaga aaatacagat cctcttttta cttatcttaa
    41401 aaatgaagct cctggtactg tcactaaagc aataaaatgg aattttacta aatttttgat
    41461 tgatagaaat ggcaaagtaa tcgaacgatt tgcaccacaa acttctccat tgaaaatgac
    41521 cgctgcaatt gaatccgttc tttaacttaa taaaaataaa aaaagatgaa ctatttctag
    41581 ttcatctttt tgcctttgcg tggcgacg
//
LOCUS       DAIGUC010000023        39448 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.023, whole genome shotgun sequence.
ACCESSION   DAIGUC010000023 DAIGUC010000000
VERSION     DAIGUC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.023"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(207..401)
                     /locus_tag="NOB46_001270"
     CDS             complement(207..401)
                     /locus_tag="NOB46_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058216.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(501..587)
                     /locus_tag="NOB46_001271"
                     /pseudo
     CDS             complement(501..587)
                     /locus_tag="NOB46_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1753..2793
                     /locus_tag="NOB46_001272"
     CDS             1753..2793
                     /locus_tag="NOB46_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI1058217.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3617..3949
                     /locus_tag="NOB46_001273"
     CDS             3617..3949
                     /locus_tag="NOB46_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HCI1058218.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4540..4869
                     /locus_tag="NOB46_001274"
     CDS             4540..4869
                     /locus_tag="NOB46_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058219.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            4856..5197
                     /locus_tag="NOB46_001275"
     CDS             4856..5197
                     /locus_tag="NOB46_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HCI1058220.1"
                     /translation="MKNYDPNSRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            5311..5550
                     /locus_tag="NOB46_001276"
     CDS             5311..5550
                     /locus_tag="NOB46_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058221.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            5617..5856
                     /locus_tag="NOB46_001277"
     CDS             5617..5856
                     /locus_tag="NOB46_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058222.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKKSSNCQLLLEVS"
     gene            5942..6613
                     /locus_tag="NOB46_001278"
     CDS             5942..6613
                     /locus_tag="NOB46_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI1058223.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            6666..8642
                     /locus_tag="NOB46_001279"
     CDS             6666..8642
                     /locus_tag="NOB46_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI1058224.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAVKNAEGKYYGGLVDTDKDGVKEAVWVDNVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTEDIAFKVNKNSFKEENRITVKNNQKAAI
                     PLTGSNGFQTYVLISCLLLGAGGLSAVVYFKKKA"
     gene            8655..9410
                     /locus_tag="NOB46_001280"
     CDS             8655..9410
                     /locus_tag="NOB46_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1058225.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            9407..10231
                     /locus_tag="NOB46_001281"
     CDS             9407..10231
                     /locus_tag="NOB46_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058226.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQPVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            10533..12632
                     /locus_tag="NOB46_001282"
     CDS             10533..12632
                     /locus_tag="NOB46_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI1058227.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVLDGKNYDGALWYVEANGTWKKADTGGKLTVSSNTVTYTASDSFLANA
                     ANYGRDYILQLHMKAKNDAKGIAPNVATVTFNNDPNKGTQRTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIALDHYKQFSIQDPVEA
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(12670..14727)
                     /locus_tag="NOB46_001283"
     CDS             complement(12670..14727)
                     /locus_tag="NOB46_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HCI1058228.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNHEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKASQAQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(14841..15053)
                     /locus_tag="NOB46_001284"
     CDS             complement(14841..15053)
                     /locus_tag="NOB46_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058229.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            15240..15707
                     /locus_tag="NOB46_001285"
     CDS             15240..15707
                     /locus_tag="NOB46_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058230.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            15704..15946
                     /locus_tag="NOB46_001286"
     CDS             15704..15946
                     /locus_tag="NOB46_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HCI1058231.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            15964..16266
                     /locus_tag="NOB46_001287"
     CDS             15964..16266
                     /locus_tag="NOB46_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058232.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            16337..18391
                     /locus_tag="NOB46_001288"
     CDS             16337..18391
                     /locus_tag="NOB46_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058233.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            18391..20223
                     /locus_tag="NOB46_001289"
     CDS             18391..20223
                     /locus_tag="NOB46_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HCI1058234.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNSVTCLA"
     gene            20936..22834
                     /gene="ltrA"
                     /locus_tag="NOB46_001290"
     CDS             20936..22834
                     /gene="ltrA"
                     /locus_tag="NOB46_001290"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI1058235.1"
                     /translation="MTNTKGISLKNKQLRHAEYYDMTETFDELHAMSVAKSNFKNLMK
                     FIIDDNNIFLAYRNIKKNKGSATAGYDGVTIKDIEKLACGDFLTIIKRRFKDYRPRKV
                     KRVEIPKPNGKLRPLGIPSIWDRIVQQCILQILEPICEAKFNKHSYGFRPNCSTENAI
                     ADCLARINQSKMNYVVDIDIKGFFDEVNHTKLMRQIWTMGIRDKQLLVIIRKMLKAPI
                     VMRNGNVVFPTKGTPQGGILSTLLANICLNEFDWWIANQWEERTVKELKHHYRKNGAW
                     DKGNIYSKLRSHTSLKEMYLVRYADDFKIFCRTGEEAQRAFYATQKWLRERLKLPISM
                     EKSKVTNLNKAESEFLGFSIRLHKKGKKKVAFTYVCRKAEENIKNKLKQQIKKIQYAG
                     AKKNRHRAIGDYNMMVIGIHNYYRIASHCSVNFTEIYRSVRTVIEARLKARGMTKNGI
                     YGQDHEGYRPYLKSKQMRYIEGFPILPIGYIKKRTPLNKRRNLNKYTKEGRKLIHQEQ
                     QAIESWKIKYLVKGFSNNKKYTVEFSDNKISKFISQKGKCAITGNELLMEEIECHHIN
                     PYHLSKDDSYKNLVIISREIHRLIHATSEETILKLLRLLKLNHYQIRKLNTYRKKAAN
                     FPISIKMN"
     gene            22951..23751
                     /locus_tag="NOB46_001291"
                     /pseudo
     CDS             22951..23751
                     /locus_tag="NOB46_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            23748..26279
                     /locus_tag="NOB46_001292"
     CDS             23748..26279
                     /locus_tag="NOB46_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058236.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            26331..26663
                     /locus_tag="NOB46_001293"
     CDS             26331..26663
                     /locus_tag="NOB46_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058237.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            26664..27257
                     /locus_tag="NOB46_001294"
     CDS             26664..27257
                     /locus_tag="NOB46_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058238.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            27420..29114
                     /locus_tag="NOB46_001295"
     CDS             27420..29114
                     /locus_tag="NOB46_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCI1058239.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLLKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            29802..31679
                     /gene="ltrA"
                     /locus_tag="NOB46_001296"
     CDS             29802..31679
                     /gene="ltrA"
                     /locus_tag="NOB46_001296"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI1058240.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            31810..32187
                     /locus_tag="NOB46_001297"
                     /pseudo
     CDS             31810..32187
                     /locus_tag="NOB46_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            32246..32509
                     /locus_tag="NOB46_001298"
     CDS             32246..32509
                     /locus_tag="NOB46_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component,
                     AbrB family protein"
                     /protein_id="HCI1058241.1"
                     /translation="MLVKEIEMKKWGNSQGIRFGKEELSVLGETNTENLKFEMVVTEG
                     KIVLTPKNKKPETLDELFANYEGEPLGKEDKYEWGNMQGREII"
     gene            32509..32844
                     /locus_tag="NOB46_001299"
     CDS             32509..32844
                     /locus_tag="NOB46_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1058242.1"
                     /translation="MKKNYHDLSQGDLVYIDLNPTKGHEQRGKRPCIILSKPNKYLNY
                     MIGVAPITTKAKPFPVHVDLNGTQKIKGQILLEHHRMIDIESRGFQFVEAVPKEILEE
                     CIEKIKLFY"
     gene            32918..34120
                     /locus_tag="NOB46_001300"
     CDS             32918..34120
                     /locus_tag="NOB46_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI1058243.1"
                     /translation="MENDTNIVMEHLKRRAKRRLFLWLFGTSAGLITILITVFVTLFL
                     ILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKL
                     LPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFP
                     NSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMSI
                     ITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGGE
                     FRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQ
                     EFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPL
                     PFLNSSKK"
     gene            34136..34780
                     /locus_tag="NOB46_001301"
     CDS             34136..34780
                     /locus_tag="NOB46_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058244.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            34791..35597
                     /locus_tag="NOB46_001302"
     CDS             34791..35597
                     /locus_tag="NOB46_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058245.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTHQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            35619..35849
                     /locus_tag="NOB46_001303"
     CDS             35619..35849
                     /locus_tag="NOB46_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058246.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYLAAKKYFTADNK"
     gene            36407..36685
                     /locus_tag="NOB46_001304"
     CDS             36407..36685
                     /locus_tag="NOB46_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058247.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHALLDYKKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIEQ"
     gene            36724..37146
                     /locus_tag="NOB46_001305"
     CDS             36724..37146
                     /locus_tag="NOB46_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058248.1"
                     /translation="MAKATRKHIYLYDMHIEVLDEIISTHDDISNYSEAVRHLCMMYD
                     PKTEEKISPSQIKLNAIGKEVSILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            37166..38758
                     /locus_tag="NOB46_001306"
     CDS             37166..38758
                     /locus_tag="NOB46_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058249.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTLEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEYGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTEREKIEYQRLNQAMEKYQAEPHKKTSGTLPGVFSISSDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEVGLKAAGRK
                     MMETLFEKEKLNDTGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNSLTKVVKEPVRYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDENRTKLSPYTREKLDELTQYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QTQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            38788..39123
                     /locus_tag="NOB46_001307"
     CDS             38788..39123
                     /locus_tag="NOB46_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058250.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            39264..>39448
                     /locus_tag="NOB46_001308"
     CDS             39264..>39448
                     /locus_tag="NOB46_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058251.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        14508 a         5978 c         7876 g        11086 t
ORIGIN      
        1 tattgaaagt aactctatgt agcaaaaaat atctagaatt tcatttcctc aaaactgatc
       61 gatattgtat ctaaaaatat atactaccta aaataggtag tatatattaa aatatgtgct
      121 tttgttagaa aaatcaatac ataaattatc atatctgtat atgtcattta ggtatttcag
      181 ttatgttata atagttttgc tgtctgctac cccggcctaa tctggcaagg ggaggaggag
      241 atataatgaa ataccttttt gattttgttt ttgcaatcaa gccacttgca gatgtagtgt
      301 gcagttacct ctgcaaatgg cttgattgca aaattgccaa aaaagacagt aagcctaccc
      361 gttaattcta taatatagaa acgtaaaaaa aaccccatca gcctgcacgc tgatggggtt
      421 tggtgatata atgaaatacc tctttgttac tcataattat accataatta gtcacgaatg
      481 caaccaatag aaaaaactac ttagaacggt agatcatcgc taataacaat gcattgtcca
      541 ccaaatggat tttgtgaagc attaaataca ttgttattaa ttgtcgctgc ttttaactag
      601 gcctctcccc ttctattata aaagaagata tatatcattt cttaattacc tactacctta
      661 aaccaaaatt taagtactac ctaatttaag tagtacttaa acaatctaaa aaatagttat
      721 cccaattgtt atgcttttat aatacgatta tttgtaacaa aatgaatatt atataattaa
      781 acactaccat atttaggtag tgtttaatta ttagcaaaac aaaaaatatt tattctattc
      841 tcttaacttc aactaagtta tgctgcacac ctttatataa atcatatgca actcattagc
      901 tagacaaact acaagcatgt agttttatct gttaattatg tactacctaa ataaagtagt
      961 ttataattag caagtatata tatttaaaaa tttaagatta atttttttat gacttgtaca
     1021 aatttatctg atattctctt attaagaact acctaatttg ggtagttctt attttttaca
     1081 ttttaagtag tatttaattg caatttggta gtattttttt attatcttat tcttagaacg
     1141 gtagtactta atataaatat aggtagtatc taatttaagt attaatggta gtatctaaat
     1201 taacaggtag tatgtaacta ctttaaagta atttttttca gattaacaca gtagtatctt
     1261 attaaataag ttaattttaa tggtagtaca taattattat atatatctga cattggtagt
     1321 acttattgta ttttttagta gtatataatc tattgttttc tagcctaaag ccttgtctta
     1381 taagaataat ataatatata ctactgaaat aaggtagtat atattactag taatggtagt
     1441 atgttttata tgcataaggt agttcttaat ttattttttg ttttgacact ggtagtactt
     1501 aattatcttt aattttaaaa ctaaatttta ttcatacgtt tttctggtag tatttaatta
     1561 taaataatat ttatttaaag tagttcttaa tgactttaaa ggtagtacat aattcatttt
     1621 atttctgatt ttaggtagta tttaattaaa aaacagtttt aatgcgtttg cattttttat
     1681 ttatctttgc tattttcgaa aagagtaggt aattttacat aaataaaaca acgtgaaagt
     1741 agaggatcta caatgactga ttttaaattt tttaaggcgg atagagttta caacgaatta
     1801 ttttatcaat ttccaaaagt ctttattgtt tctgacgaat acaaaaaaat gaaagattca
     1861 actaagattg cctatatgct tttaaaagca agattagaga tcgcaatcag caaacggcaa
     1921 atcgatgaag aaggtaatgt ttattttact tatacgacaa atgaactatg tagagtatta
     1981 aactgccaaa aacaaaaagc gatagcaatc aaaaaagagt tggaatcctt tggtttatta
     2041 ttacaaaagc agatgggatt taacaaacag ttagggaaaa ataatcctaa tagactatat
     2101 ctagcagaat taaaagtctc agaaaatgat atctacttac tcgaaaaatt tgatagagag
     2161 aatagggaaa acgttgataa atcagagggt atgaaaatca tacccaccct cgacgaaaaa
     2221 tcagacgctg aatcccttgg ggctcaagag ggtatgaaaa tcataccgtg ccaaaacgtt
     2281 gataaatcag agggtatgaa aatcatacca gaacttaata ataatatatt agacactaat
     2341 agacacaata tagacactga aaaagaccgc ctacaagatc aattgttgtt agacaatttt
     2401 gagacaatta tgacaaacga cagcattgct acgtttgtcc ctgaacgagt attaaatttg
     2461 ataaaaacat tttcttcaag ttacagtgaa gctcaaaaaa ccgtccagac tattcataat
     2521 gcaaagaaaa aagctgaaat agaaagtgat atttcgatag tttttgaaga actcgatagt
     2581 tattatgtca atgcagaaca agaattatac acgacactgt taaaagccta tcaaaaatta
     2641 aaaaccgaaa aagtcgaaaa tatccagaac ctgatttttg tctatgtaaa aaattggttt
     2701 atcgaaaaac caatagctgc taaagtatca agtgaaaaac gtttgaatta tgcaagctcc
     2761 ccaagcacta ttacgaaaga ctggttagag tgaaacttta ctgacaaagt gattgttgct
     2821 tcatggagta acattaaaat taaaaatttt ttattattct aattatatta cgaatattac
     2881 aaaataatag ctattttaat agaatttata agttaaaata ttatgataaa aatcacaaac
     2941 gtagcctttt acgtcataag tgttaaaaga aataattaat ttcaaatata gaaaagggaa
     3001 cgtatgtttg catactcctt ttttttgagt tataataata cgcgaagaga gataatttca
     3061 ttatttaaac aagctaaaaa tcttgatatt acttcttttc aggcaatacg aatattattc
     3121 gcttacattt tttgtataaa tttaattgtc tgctatgctt gtgatgaatt gattttcgtt
     3181 ttgcactttt ggatgataaa tttggacaat tgaaaataca aaaaaaagaa aggcggtatg
     3241 aactcggaag gctggtaacc ttcgtcagcg ttcatacacg gcattaagat ttggccctta
     3301 atgcgttaac ctttcagtgt tacggtatta cccgcaatgg atttagtata acagatattc
     3361 aaaagtgata ccactttttt tggctgtgtt aaggttaaaa atacgtgata ttacgatgaa
     3421 tctatgccta agcataatgt tataaaaatg tccgtgtggc tctttgccgt atgacgaacg
     3481 ctgaaattag agggaacgca tgtttggatg cgttccctct tttttgtttg tcatgaacga
     3541 aaatcaattc tctatttttg aaaaataaca agaaaaactt gttaaaaata tttaaagaaa
     3601 ttgggtggtt tattttatgt catatacagg aattttgagt ctcaaagata tttgtcacta
     3661 cggtaaacgg tgtaccgcta cagagaaaat cacgaagaaa ctatcaactg gccaaagtaa
     3721 aaccgttgtg cagtgtaaga aatatataat ccagaaagac aaagtctcag aggaaatgat
     3781 ttattacatt gggaaacaaa agcaaataat tttaaaagat cctatcccct taaaagagct
     3841 atatccaaca atcaaacatg tttatgacca aaacggtgta ctgattggtc gaagaaaaaa
     3901 tggagtcttg cgttgtaccg caaaagggat ggggcgtttg atcggctgaa ttgatcattc
     3961 tcataacttg tattttatcg tttttcgctt gcttgaaaat attgtcgaga cttctaaagg
     4021 aacttagagt cactagaaaa ataaggagta gacttgatct atcaacaatt cccttcgggg
     4081 agtgacgggg taggttttta cgattggtaa cgtaaaaaat tggtcaatcg agtaaatgcc
     4141 cttgtttgga tagtggtgaa atgaatttgt gtaaataata tgcacagagt aaacaagagg
     4201 gaatttagaa gttagacaag ttagaatagc gcctagatta atcatgagca gctactaagg
     4261 gatctaggct ttgacgcaaa ctcatggaat aaggagtagg tcttctcgta atggggagga
     4321 cgcacaagaa attgtgtcgt gtgctgcagt acatgtagat acttgcgaag acgttgatct
     4381 ttggatcaat cgagcattta ccgttttcta ctagggtttc tcgtttcgga cgccataaac
     4441 gagtcgattt attttatata tttttgagtg aacgaaaaac gataaaaata ttcgttatga
     4501 agtaaaacta atttagtaga tagcaaaggt ggtagaggaa tgattcaaaa atttgcgaaa
     4561 atgagtaaaa ctgcatggat tgaaaagctt gaaaatgact tgagtgtcat gcgattagct
     4621 ccaaagaaat tcaaacgaga gattgcagaa aaagaagcaa ttttgtcggt attgaatgcg
     4681 gtagacgata aatgtccagt aaaaattagt ttttcagata tagcaacaat tatcgaaggt
     4741 atttattatg gtgaagttga tgaagagata tcttctacaa aagatttatt agattttttg
     4801 gataaaaaca aagatacctt tatagtacta actgattatg aggaggttac aacaaatgaa
     4861 aaattatgat ccgaatagcc gatggggaac acatacgatt aaggtttctt tccaacgttg
     4921 ggattacaaa ggatttgtga cgtttagaag aggcggaaat tgtaaaggat tagatgtttt
     4981 agcattagac gaggatgatt tatacgatca aacattgact gataatccaa ttggattcgg
     5041 cttgctacct gaagatgatg aaggtaatga atggtttaaa atgacgctta tgaatgataa
     5101 tggagacgaa ttatctgttg aagatacttg gtcatatttg agtgattata ttgtcagcgt
     5161 tgaaatcatt gaatttgtag cggataaaga agaataaaaa ctggaggaat aaattttaca
     5221 gataaaggct tagaaggagt cacgacgatt aataaaaagg tagtattacc ttaggcattg
     5281 agtaaggaat ttatttagga ggaaaattag atggcgcgac cagttttaga ggcgatggat
     5341 atggatactt tgacaaaagg aaggtatgta cagctgttag ctcgtggtta ttcacctaaa
     5401 gatgtattca aatccctgtc taaaggaaca gatatggaaa aagaaagatt acgaaaagaa
     5461 ttcgattatt ggagaaccca taatggaatc aaggatttga aaccagcacg gccagtaatt
     5521 aaacgaaaga aaaagataac ccaagactga agtgtagagc gtatgtgatc ataggctttt
     5581 ttatttttgc aaaaaacaag gaaggtagga aaactcatga attatgaaga aatcgaaaac
     5641 agaaaaaaag tgtcgaaaga aatggaagaa aagttgctaa aaacgatgaa acaaaaacac
     5701 cttaaaagat tatctgtcat gcaatatatc aatgatatgc agataacagg aaaagagaaa
     5761 gcttgtttgt taggttcaat gaaaaacttt gaacagttga gacgaactta tgtgaaaaaa
     5821 agttctaatt gtcaactatt gttagaagtc tcatgacatt cattaataga attcattttt
     5881 aaaacttttt ctatggaaat gagaaaaaga ttttttgttt tgtctgaaag gaggtagctg
     5941 gatgagaaaa tggttatttg gttttttagg agtcgcttta atcgtctttt gcagtgtgtt
     6001 tggctatgtt agctaccaaa aacatgaagg agaggtgttt aagcaaaata tagaaaaaaa
     6061 gatgcccgta gatcaaatca atgcacatgc aaagagttat aaggaggatg caacgaacgt
     6121 caataatgat atgtctttgg ggcaaatgtt gtccatacaa aaagaagcaa tcgaaatggg
     6181 cgtcaataaa caagtatttg cacaaattca gattcctgca cttggtttag cattgccaat
     6241 ttttaaaggt gcaaatcaat acactttgag tcttggagcg gctacttatt tttatgaaga
     6301 tgctgaaatg ggcaaaggaa actatgtcct agcaggtcat aacatggaaa tgccaggtgt
     6361 tttattttct gatatccaaa agttgtcatt aggggaggtg atggacttag ttagtaacga
     6421 tggcgtctat cgttacaagg taacgcgtaa atttatcgta cctgggtact ttaaattaat
     6481 cgatggcgtt cctgaagaga actctttctt gtctttgcca aagaaaggag agaaaccctt
     6541 attaacgttg tttacttgtg tttatacgtc acaaggaaaa gaaagatacg tggtacaggg
     6601 agagctacaa taacaaggtt ttaatcaacg cgagtcgttg aaatatgaaa tgaggagagt
     6661 aaaaaatggc aataaatcgg tatgtaaaaa aagctggaat gcttgttgga atgttaggaa
     6721 tcattgcagg ctgctttcag gggtatcaag tacatgcaga agatgtcacg caaaaaacac
     6781 caccagagaa ggtcaatatc acggttcata aattaatgta cgatcaagga acgcaattga
     6841 atgttgatat tgacgggatc aaaaacgatg gttatacgca cgatcaatat cctacaggtg
     6901 taacgaaata caacaaggca gattatggtg atgttgagtt tacgttagga aatattacgg
     6961 atcaagtatt accgagagaa gattctgatc taaccaacgc gaaagtggac gagattgtac
     7021 aagatgtaga agacaaggga tctaacagtg agtacgtcaa gaatgcaacc aacaaaatta
     7081 cttcagctgt agatgaaaat ggtgagatca cttttactga tcaaccagcc tatgtcaatt
     7141 ccaaagggaa tgtatatgtg gtttatgaaa gtaaatccgc tgctggatta gtcacacaaa
     7201 aagcaaaacc aatggttgtg attgcgccaa tgacagataa aacaggatca ggatttttaa
     7261 aaaatattca tttgtatcct aagaacattg tttctaagtt gagttttgaa ttaacgaaat
     7321 ttggtgacga tggcgcagac caaagcaaac aaaccctttt aaaaggggca aaatttgagt
     7381 tatacaaggg cgaacctgga aaaggaacaa aattgggtga tcttgtatcg gatgatcaag
     7441 gaaagctgac tgcgactgat ttgacgttag gaaaatacta ttttgtggaa gttccttcgg
     7501 aagttgtagt gggatcagat caagaaccaa cagcagatca atatttatta ggcgcagacg
     7561 ctcgcaacga tgcgcacaat aaattaacct ttgaaattac gaatgatggc gtgacaagtg
     7621 acttaaaagc ttcatacgta aactataaag caccagtgat cgataaaaca gtaacaaatg
     7681 gaacaggaca agaacattct ttccaaattg gtgacgcagt aaattatcaa ggaacgattc
     7741 atattccaac agacattgca ggtggcgcag acggtatcac agtaaacggt gtgaaaagcg
     7801 aaacttctcc ttacagtgta tttaaatggg gagatacagc aggacaagga ctttcttatg
     7861 tcgctgctaa agcaaatatc aaagtaacaa ataaagatgg atctgtggta ttaaaagaaa
     7921 atacagatta taaaatccaa aattcagaaa atggctttgt gatcgatttt atcgtgaata
     7981 atggccaagt aagtgatact gtagcaagtt tacacggaca agatcttcaa atgacttata
     8041 acatgtatgt aaatgacagc gcagctgttg ccaatccatt aacaaatagc gtggatttcg
     8101 tttataacaa caatccattt aatcaggaag aacaccacga aaaaacgaaa gctgacgttg
     8161 tgacttatgg tgcaaaattc ttaaaagtcg atagcggact atttggaaca ggaatcaaag
     8221 caacaccgct tgaaggcgca gaatttgctg ttaaaaacgc agaaggaaaa tattatggtg
     8281 gattagttga tacggataaa gacggtgtca aagaagcagt atgggtagac aatgtagcaa
     8341 atgcagcgat tctaaaatca gataaagaag ggcactttga aatcactggt ttaactgaag
     8401 gtgaatattc attggaagaa acaaaagcgc ctgaaaacta tcaaaaatta acagaagata
     8461 ttgcatttaa agtaaacaaa aactcattta aagaggaaaa tcgaatcact gttaaaaata
     8521 atcaaaaagc agctattcca ttaacaggta gtaatggttt ccaaacgtat gtattgatct
     8581 cttgcttgtt gctaggagca gggggacttt ctgcagttgt ttactttaag aagaaagcct
     8641 agaaggatca gctaatgatt attcgtaagc ccccaaaaag aagagtcatg cacaaactga
     8701 tgatattttt ttggttgctg tcggcagtag cagtctattt aattccagtt gtggaaacaa
     8761 atgtagcgaa atttcaacaa cagcaaagaa ttttagccat tgaaaatctt gaaaaaacag
     8821 attcttcttt ggatgttgcg aaaatagagt taggcgatcc tgttggtgtt cttacaattc
     8881 caagtatttc tttaaaacta ccaatttatg acggaacttc cgacaaaatt ttagagaatg
     8941 gtgtagggat tacggaagga actggcgata ttacaggagg aaacggtaaa aatcctttaa
     9001 tcgcggggca cagtggactt tataaagata atcttttcga tgatttgcct tcagtaaaaa
     9061 aagggcaaaa attctttatt aaggtaaatg aagaacaaca tgcctatcaa atttatcgaa
     9121 ttgaagaagt taaagcagaa gaattacaaa aaaattattt agattatctt atgcctgaaa
     9181 aagaccaaga taggatcacg ttaatgacat gcacaccaaa aggtgtcaac tcacaccgct
     9241 ttttagtgta tggtgaacga gtttccttca gtaaagaaga tttaaaacta cagaaaaaag
     9301 caaaaaatag gaaatcaatt tcattggatt ggcgattagc actgctattc gctttttttt
     9361 gcgttcctat tatttttatt tataaaaaaa taaggaggag atcggaatga ataagagaaa
     9421 atggctgttt gtttgtgtag cagctctctt ttctactgta gcttattcgc aactgtcttt
     9481 cgctgacagc agtgatagta gtaccactca aacaatagat aattcaatta ctgcaccaag
     9541 cgaaacggac agttcggaga atactacaga agaaacggca gattcaaata taagctttac
     9601 tgaatcaacg aatccaacgt cagaaagttc ttcagagact tcagaaaagc cgcaagacgt
     9661 agaagatacg caagtgatca agcaagccat tcatattcaa aaaattattt cttcgaatca
     9721 aatcaacaat caaggcagtc aagtagccca gcaagaaggt atcaatggcg caaagtttat
     9781 tgtctacgat atcacgaata tcttagaaga aatgtcacaa gatgataatg agaaaaatca
     9841 acctgtagaa ataattgagt caaaattgaa agatcgagca aaaaaacttt catacgacca
     9901 gttgaaaaaa gtggctgaag gagaaaccaa aacgattgat gatcaggaag gcgtgattga
     9961 attttccatt gaagtacctg caaacaaaaa acaagcatac tatatcgtta atgaatcaag
    10021 ccctgaaaac atttcaaaca gtgaagatat tgttttattg acacctgttt caaatgaaaa
    10081 aggtgaattt ttgacggatg tttggttata ccctaaatca gagaaatcag agccgaaaga
    10141 agaaattaaa aaagttgtgt caactggtgt aaagaagaac ttttttgaaa attgttggga
    10201 attttttgct caattatttt ttgataatta ggatgaaatg atgaaaataa taagaatatt
    10261 agtttttaat ctatcctttt tagccgcaac attattgtgt tgcggtttaa ttttttctca
    10321 attatcaatt tatccaagat atcaacgatt gttcattcat tttctaaaca ttcaatgtgc
    10381 ttccatgcca ttagaggtga ttaaaaagct cttgatcagt ccaattttta tggttagttt
    10441 ggttcttctt acaggattgg taacgtgggt attaggaaaa aaagaatgaa aagcttacga
    10501 tcgtttaaaa aaaatattag atggagggca ttatggaaaa taaaattcat tgcactacgg
    10561 gaagagtaat tactttagtg ttgtttttgt tccttcttct ttttgcgagg ggaactgcag
    10621 tccaggcctt agaaaaagtt gatccgagtc aaatcaaaga aaataataat ctggtgcttt
    10681 atcatgatag tgattcattg agaaatatcg aagtaactgg gatcaatgga tttaagatac
    10741 tagatgagta ttcaactaaa aaacaaaaag tacttgcttg gccaaaagtc aaagatttga
    10801 aaagtacgtc aaaaatcgtt gcccattatc aaaaagtagg tacttatcta ggaaaagaaa
    10861 ttgattgtga cgtgactttt tctaattttg tagcgcacgc tggggttaac caagacggat
    10921 tagctaaaac aattaatggc aaaaagtatt ataattattt gctctttgat aaaaatattt
    10981 atcgaggatt tttcatgcag tcaatcaatg tcatgaatgc aaaactagaa tttaagtatg
    11041 caggaacaaa aacaaaagta gctttgagtg aaccacagcc agaaattcaa tcaaaaatga
    11101 gatcgatgag agcagctggt attgatttaa acgatacatt tctatccatt tatagtttaa
    11161 atggacagta tcagcaacgt gtgtcttggt ataatgacaa taatgaatct gtcggtgaac
    11221 gtaatattga tatgagagaa tttgttgggt atgaaaaaat gggtagctta ccttattttg
    11281 tcacaacaga tacagcatgt gcagaataca aagctcctgc gttatcaaca aacaatttaa
    11341 cttcaaaagt agtgggagga cgtgcagaaa aggcttatag ctcgaatgat catttcaccg
    11401 atgttgtagg agctgatact tatcacagaa gtggtgtaac gtatacgctt caaggcgctt
    11461 ccccaacatt catgattggc gcaaatacga atagtatgat gtttagcttt gatactgcat
    11521 tgctatggac accacaacca tcgaagccta caaaagaagt gtttaacaaa gctaatactg
    11581 aagaggcagc acacaatatt gacaaaaaag tgattccaca aggatcagat gtttactatc
    11641 atattcacca aaaatttgat gcattaacag tcaacacaat gaacaaatac aaatcattta
    11701 aaatcactga tacctttgac agcaaaaatt ttgatatggt attggatggg aaaaactatg
    11761 atggcgcatt gtggtatgtt gaagcgaatg gtacttggaa aaaagctgat acaggaggaa
    11821 aattaactgt atcaagcaat acagtcactt atactgcttc tgacagcttt ctagctaacg
    11881 ctgcaaatta cggtagagat tatattttgc agctccatat gaaagcaaaa aatgatgcaa
    11941 aaggaatcgc acccaatgtg gctactgtaa cgtttaacaa tgatccgaat aaagggacac
    12001 aaagaacaaa tacagtagaa aattatttct ctcttaaacc aaataaaaaa gtggaacaag
    12061 atgggaaaga tgttgatggt cgaaatgatg gtaaaaaagg aacgcctaca gctcctttaa
    12121 atgcaggatc tgaagtacaa tatctagtca cacaaaaatg gcatacaaaa ggtgtagaca
    12181 ttgcgctcga tcattacaag caatttagta ttcaagatcc agtggaagct cgtttgacgt
    12241 ataaagaagg ttctgcgcga gtgatagata tgagtacagg aaaagatatt acttcagaag
    12301 gtacactaac ctatgatagc aattcaagaa cgctgaagtg ggaagcttcc gctgatttct
    12361 taagtaaaaa tcttttagat ggacgagaaa ttcaactgat atttacagct aaaactcctt
    12421 tgaatgaaga attggatatc gacaaccaag caaaagtttc agtagaaagt attgagaaag
    12481 caactaatgt agtaacgatt ggggtaaaac ctaacttacc tcagatcatt gtgccaaaaa
    12541 ctggatcgaa tcatttagtg ctaactgtta ttggaagtat attatttctt actttagcat
    12601 cattgggcta tgtagtttta aaactcaaat aaatataaaa acaaggctga gaatcagcct
    12661 tgttttcttt tatttgaaga ttggattcgc actaataaat acattatcta cgccaattct
    12721 accagcagag tcaactacaa aattatgacc taatccgaga atactttggt tattataaag
    12781 taaatttgca ttatgggcag ggctattttt ccatcctacc atggcatcga tagcaccatc
    12841 gtctgataaa aggtcatcaa tatacagccc agtttgactt atgttttctc ccttagcacc
    12901 gtagcagcct aagctttcca ataaatcttg gaaagtacca ccaccagggc gatagtgact
    12961 gaagctgact tgtaattctt tagctcgaat atctgcagcc tgttgaacaa tatcattgaa
    13021 ttgcattggg gcaacaccat tttgttggcg ataatcattt aaccaagcaa gttctttttg
    13081 acgcataaag ttacgtaatt cgtctaatga aatcttttta tatttgaatg tgattgtttt
    13141 attttgatcg acgttattaa tggatcgttg gccgttttta tccacggtaa cggtaggatc
    13201 gtcatttctg cacaagaaat aattttgatc agtcatgttt ttccaaggag tagcaaagct
    13261 atccccttcg tatactgttt ttgattcact agagagaaca gcgttggtat cagcatttac
    13321 atgattaaca gtcacattaa atttacgagt gtagttgaaa atataatttt gactttcagt
    13381 cacattgttt aaggttactg aatttgttgg ttctacccga tcgtctaaaa catatccttg
    13441 aatagaagga gcagttaaag tgacactgtc accgtgagtg acattgacta tctgttcttt
    13501 caaaatatta actcgtcctt cgtttttgta gttgttattg cacaacaaat tgatttgatg
    13561 cacttgatta taattgaatg tgattgttgt attacctgtg attgttttgc tttgagtatc
    13621 attaccaatc actttgtagc taaaattatc tttagcgcct tcgctatatt taaatgcttt
    13681 tgccttagca gtgtaagtag aaccagaagt tacttttgct tgatctgtag caatcacttg
    13741 acctgtttga ttgtcaatat ggttaatagt aaccgtatat tcttttggtg tttcaggttt
    13801 gtgttgcaac cctttaaatg cagcatcaag actattttta gcattattta cttgggcttg
    13861 agaagcctta gaatcgtcta gtactttttt agcattggat aaagcagtct gaaaattatt
    13921 ccaagattct tctgtaaaat ctcctttagc agttgatttt actcggttgt ataaagcttg
    13981 taattcagct ttattcacag taggaactgg ttttttcttt aatcctttgt aagcagaatc
    14041 taatttattt ttggcactat ccacttgttt ttgagtcgct tttgagtcat ttaacacttt
    14101 cttagcattg tttaaagcgg tttggaatgc gttccaggta ttgtcggtat agtcaccttt
    14161 tttagttccc ttaacgctcg tataaagagc ttctaaagct gatttattca ctttgggttt
    14221 agaggtgtca gcgccatacc aaccgatacc ttcgtatttc cagccatagt ctttggttaa
    14281 ccattgtact tctttccaac ttgcagtgta gtgatgtgag ccagatttta caccaggaag
    14341 gaaaaggcgg tagatcggtt tattattttt ttcggcagaa cgccaggctg gcccttcata
    14401 agtccagccg taatttttag tcaaccattt cacttcatcc caactagctg tgtaatggtg
    14461 atcacgaaga cctttattgt acaaacgata gacaagatgg ccaccgctag tcggtgcttc
    14521 ccaggcgggg ccttcataat ttccccattt tatctttact agatggtcac gttctttttt
    14581 gctagaggtg taaaaatgtt catgattatt tggattgtaa aggcgataca tgacgttagt
    14641 tgaagcagcg tcaacagatc cagcaagact aagtgaggca gcaaatgttc caatagctaa
    14701 aacagttttt ggattaaata atttcatttt ttcaactcct aaatttaatt aaaaatgttt
    14761 acatgattat tatatatcgg ctaaccgata tagtcaataa aaaataagaa aagccttata
    14821 taattttggc ttttcttatt ttatttgtta gttgaagtat taatatcaac gatttcttca
    14881 gccaatttat ttaatttcat agcatttatg aatctcatgt tgtctatact agagcgtttg
    14941 ttggcaaggt cacttactgt agttaagggt acgccagatt ctatggatat agaacgaact
    15001 gatttaccac tatcaaacag caaccattcg attttctttt tatcagcgta catttcaatg
    15061 ctccttcttg ttttttcttt attatagctc ttttttgtaa taaatcacaa tatcaagaga
    15121 aaaattttct atagaaaggt ggatttttat gagtattcgt tctccgtgta tccaaatgag
    15181 gtttgttgct actttcgtta tttgatatac taaaaataaa caacgaaaga aggaataaaa
    15241 tgaagaaaaa gcaactatgg tttgtctcta tgtttgcaat attttttatt attttaagtg
    15301 gatgttcaag taataagaaa tcggaagcta aagaagataa tagtttattg caaccaggaa
    15361 ctgtttggaa agaagaagta ggtggtctta ttcataattt aaaaattata gatgatacta
    15421 cctgggaata ttctgaaagt gtatggcatc cagatcctgt acaaataaca gttaagaggc
    15481 aaaaagacta tgaaggttta gaaagataca aaatagtaga ttctgcaggt attagggaat
    15541 ttataaacaa acctgattca ttatttattg ttgttcccta tgagaaggat ggcgtaaaaa
    15601 aaataatttt tcttggatct agcaaggatg agaagcgaac gaaagagaaa ttaattcatg
    15661 atggatcaga gttaaataaa tacaaattac aaaagactag tgagtgattg ctagtctttt
    15721 tatttatcct gaaggaggaa tcacagtggc aaaagttaaa acaccattcg aaaaagccgc
    15781 gtctaaaatc ttagaacgcc gtggtgtttc tgaaatacag tggaaaaaag aagttcttga
    15841 aaaagcacaa tttgacctat tacgaggaaa agataaggac ttagaagaat atatctatca
    15901 acgtgaacgt gaaaaacttg tattcgatga aattattaaa cattaaaagg agcgaataat
    15961 cttatgtttg aatcaattac aatgaatttt ttaactcaac cgaaagtagt agctgcagtt
    16021 gatattttta gagcattaca aactgccgca actagtttga aaaataatct gatgattttt
    16081 gctgctgttg cggcagtggc ttccattgct cttggaggta ttttcttctt ctttgggcga
    16141 agaggagctg aaaacgggaa gacacacgta ggttatgtat tgttgggggt aggagttatt
    16201 ttagctgccg cttctattgt agtttcaatg ttctcaatgt ttggacaaac cccacaagga
    16261 ctataaaaaa acaagtagaa ggagtaaaaa gtacgtggct actttttact ccttttttta
    16321 tggaaggaga atattcatgt tttttacgat ttcaggcaat gcaaaattgg ataaagagtt
    16381 aataagaaaa gcaacgaaga aagtgggaaa gcgtacttcc tttttaccga aaacaattaa
    16441 atattctgtc attgaaacgg aagaacagct acatgtgtta ggacaagtgt tagaacaaga
    16501 gaatcaatct tctgttaaat tgactctcac gttacatgat aaagaaggaa aaatagaaaa
    16561 ggctggcaca gaatacgttt ttggctcact ggattatcaa atttcagaag gtttttatcc
    16621 tacattgatt gatttaatcc gcctagatat atttaaagat acggatgaaa ccatgagtgt
    16681 ggaagagtct tatcgaaacg aaaaaatttt acaagtttta gaagaagagt tagaaagcga
    16741 ccaaagaaaa gtgaatcaag tgagtgaagt cgaagcaaac gaagaagtac catgggaacg
    16801 cccaatcttt ccaaaggatg aatcaaaaga aaaagagaaa ggaattattg acgaacaagc
    16861 tgacattttg actcataaat caatatttga ggaagagaac gaggtaatgg gtcaattgga
    16921 ggtagatccc tttgaagaaa caatggagga tgaagagacg gccgaagtag aagttgatcc
    16981 agttgaagct aatgaagacc caacatggac tgaaggggat tctcaggaat atattgaacc
    17041 acttatcagt gaagaagtag agaaaaatga aacagagata caaaaggcaa cggtatttga
    17101 ttatattttg gatcaatatc cgccagagca tgaatggatg aaagaaaaaa ataaattatt
    17161 tttaaatgaa ctttattcga aatatcaatt acctcaaacc tatcaagcat ttttagagag
    17221 taaagaagaa ttaatctcac agggtaaagg cacactttta gaacagttag agtctgtcca
    17281 atcaacaaat tggcatgagc ttgcacaaga agatttatta gctacttttg aagaacgtca
    17341 acaagaaaca gatcaagaaa ttaatgagta tgcgacggaa cagtcgtcga attgggagaa
    17401 agcaaaagag gaactaaata aagaagaaca gcgagtgatt gaagaagaag tacaaaaaat
    17461 taaagagcgg tacgaaaaga aacgtgacaa tgcgtattcc ttgtgtgtag aaaagatcaa
    17521 caattttact cagacgaatc aagaagcatt atcgaaagaa aaagaaaact tattaaaaga
    17581 acgtataaaa gaacgaaaag aagaatttta ccgagggttg cgtactgata agctaaggat
    17641 tagcaaagaa ttaaatgaac aactgaataa actctatcaa actacgactg aagttctgat
    17701 ggaaaaacac gagcagatcc aacaagaatt acaagcacaa attccaaaat ggaaaaaaga
    17761 gtatgaaatt caccaacaag aattgaaaga acaagaagaa aaacaacgga aaaaagaaaa
    17821 agagcgcgaa caattagaac taaaaaaacg tgaacaggat cttgcggaac aaaaaatggc
    17881 gatagaaaaa caacggctag agcaagaaaa ggaaaaagaa gcagctgctc gtaaggaacg
    17941 tcaagaacaa atggatacat tgcgacaagc acagttaaat tatctgacac atcctcaacc
    18001 agtagctgct gttcaaacgc cagtgaacaa ccaagcaaat ttaactcctt caccccagcg
    18061 ttcctttaac ggatggatgg tgggatgtat tgcaagttta agcttgcttc taggtggagg
    18121 aacagtattt gcttttaatc atatcaatca atcttcacag gctgattctg tagccacaac
    18181 ggcgtcaatc aaggaagaag cccaggaaca agcaagaaaa gagtatgaac aacaattaga
    18241 agaattattg aatcgtacca atcagtcaac aacagagtca agcatggaaa atagcaaaga
    18301 gagtgattct agtaaggcta aagaaggatc aagcgattca actgtacaat caaacacttc
    18361 cgaaagttca gaatcaaatg aggtgaaata atgcgtgtta gagaaacaac gaagcgaaaa
    18421 gacaaacgat tcaatttaga aaagaatagg tatctttctc atttctatcg ctatactccc
    18481 tcaggagaag agctaccaga aaaacatgac aaacgcattt cgaaaaagat tttttatagt
    18541 ggacttgtat acctcccttt agagtattta gtaacaagag taccagaagt tttcaaccga
    18601 ttggaaattg ttaagggaag cttacaagga ataaatctgt ttcaattaca ggaaatgcca
    18661 caggtctttc attttgattc agctggtttt tggaatccat ttactcctac aactagtttg
    18721 ggtacacgtt tagcaatttc gacagtttgt gtggttccag ctgtacttat gggattgaaa
    18781 atggacatgt ggtttcgtcc tctagcagat ggacaaaaag gggataatcg attaatgacc
    18841 ttaaaagaaa tccaacagat ttatccgcaa atacctgaaa caaaaactac ttttccaggt
    18901 tatggaggta ttccaatcac acattacaaa aaatattggt acattcaaac agatactgtt
    18961 aatacgtgta ttgttggtac ctctcgatca gggaaaggtc agattgaagt gttagccacc
    19021 attgacaatt tatctcgtgc agaaaaacaa agttcaatgg tcgttaatga tccaaaaaca
    19081 gaattatatg ttggtagtaa agatgaacta gaagctagag ggtatgatgt atatgccttt
    19141 aatatcaccg atccactgca atcaatgagt gataatccat tggcactcat cgtgaaatac
    19201 tggaaacgag gagacataga tactgcaaca cagttaacca atactttcac aaatacgatt
    19261 tattatgatg ccaacgcttc agataacaaa tactttaacg aaaacgcgca gaaagctgtc
    19321 aatgcgctta tttttgcgtt gttagaacaa gctgatcaaa caggagatta ctccaaattg
    19381 acaccgaata atctcgttga gcttctttct gagattggcg gttttaatta ttatccagat
    19441 ccagacaatg aattcaaaca gttgaatgcc ttagatgaat ttatgaatca gttgccacct
    19501 ggaaacattg caaaaaaaca atatggggca acgaaaattg gatctgataa agcgaaggga
    19561 aatattttat caacggcaat cacgggattg aatccattta ctctaacgaa aattgcaaag
    19621 atgacttctc aatcaacgat tgattataaa tcggttgggt ttccaaaata cttagatttg
    19681 aaattacatg aaagtctttt aaatcaacga gtcgtagtag aattttatca taagggaaag
    19741 aaatttcatg aagaacgtgt caaagtaggc tataaaggat tttgtgaaat caattttgat
    19801 tgtcatttag ttgcaggtga tcaagtttgt ttaaaatacg atcatcaagg aaaagaatat
    19861 gtggcttggt atgaattttc tcaaagagta ttgaaagacg aagagggtaa tatcgtttat
    19921 cggaaaaaac gaggagaaac ccatttgcca gaattagaaa aagaagccgt tctaacatta
    19981 gatgaggaga aaagtaactt attagtagag tctattcgga tgcactatac cgataaacca
    20041 atggctattt ttatgcttac acctgattat gatccatcta accatatcat tgttagtatt
    20101 tttcttagtc agttatataa agaattatct acgcaatgtg ttaagactaa aggagataaa
    20161 tgtcaccgca ggattcattt tattttagat gaatttggga atagtgtgac ctgtttagcc
    20221 taaggataaa agaggctagt tccaacgaac attggaataa ctttactatc gagaaatcaa
    20281 atgacggggt aacgccctga agggtttcca ctgatactgc gacatgcgtt agtaggatgt
    20341 gcatccaaac gcgtatgaag ctcgctgaag tcggcagaag ggtaccgtaa ggaaagacac
    20401 gatacgtatc taccacgcaa gtgctctaga ggtagggtat gtacctgata tgtcgggtgt
    20461 cctaaaaagt tcaataaggt gagaatgatt tgattatctg acaaacttgc gaatggaatg
    20521 tctgaaacga ataactcata gaaatgtgag ggggaagggg gatacgtcct ctttccattg
    20581 actcgaggtt gagtaaaaat gtgtttctat gaaaaacctt gcatggttaa aggctatgga
    20641 gtagtcaaca ggcaaaagca agcacctaag ttgaaatcta tggatagata gtaaggaaca
    20701 ggggaagcat ctagcacgga gggagcatac cgaagatgtg tttctaagga aaaaccgaaa
    20761 tcggttataa cttaggtgaa tagatgtgaa agtagagcca cgaccagtga aaatttcgta
    20821 atgaaattgg aggaacaggc tcaagtcgtt atttataata taagaaacct atttaaaatc
    20881 atggattctc gtaagactaa aaaggtcacg aaccagaatg gagcgtgata aaaccatgac
    20941 taacacaaaa ggaattagct taaagaacaa acaactcaga cacgccgaat actacgacat
    21001 gactgagact ttcgatgaat tgcacgcaat gagtgttgca aaatcaaatt ttaaaaatct
    21061 catgaaattc attattgatg acaataatat ctttctagcg tatagaaata tcaaaaagaa
    21121 taaaggaagt gcaacggccg gatacgatgg tgtcactata aaagacattg aaaaattggc
    21181 atgtggtgac tttttaacta ttattaaaag gcgatttaag gattacagac caagaaaagt
    21241 taaaagagta gagatcccga aaccaaacgg aaaacttcga cctttaggaa ttccttcaat
    21301 atgggacagg atagtccagc aatgtattct acaaatttta gaaccaatat gcgaagcaaa
    21361 atttaataag catagctatg gattcagacc aaattgttct acagaaaacg ccatagcaga
    21421 ttgtcttgct agaatcaatc aaagtaagat gaattatgtt gtagatattg atataaaagg
    21481 attctttgac gaagtaaacc ataccaaact tatgcgtcaa atatggacaa tggggattcg
    21541 agataaacaa ctccttgtaa ttattcgtaa gatgttaaag gctccgattg ttatgcgaaa
    21601 tggcaatgtt gtttttccaa ccaagggtac tccacaagga gggattttaa gtacactgct
    21661 tgcgaatata tgcctgaatg aatttgattg gtggatagct aatcaatggg aggaacgaac
    21721 tgtcaaagag ctgaaacacc actatcgaaa aaacggagca tgggataaag gaaatatcta
    21781 ttcgaaatta agaagccaca caagtttaaa agagatgtat ctggtacgct atgcagatga
    21841 ttttaaaatt ttctgccgaa caggagaaga agcccaaagg gctttttatg ccacacaaaa
    21901 atggctcaga gaaagattaa agctcccaat ttcaatggag aaatctaaag ttacgaacct
    21961 aaataaagct gaaagtgaat tcttgggttt ttcaataaga ctccacaaaa agggaaaaaa
    22021 gaaagtggct ttcacgtacg tttgtcgcaa agcagaagaa aacattaaaa ataaactaaa
    22081 acaacagatt aaaaaaattc aatacgctgg agcaaaaaaa aataggcacc gagcaatagg
    22141 tgactacaac atgatggtca tcggtatcca caattactat cggatagctt cacattgtag
    22201 tgtcaatttc actgagattt atagaagtgt taggacagta atagaagcaa gactgaaagc
    22261 tagaggaatg acgaaaaatg gaatctatgg acaagatcat gaaggatacc gtccgtatct
    22321 aaagtctaag caaatgagat atattgaagg ttttccgata cttccaattg gctatattaa
    22381 aaaaagaact ccactcaaca agcggagaaa tctaaataaa tataccaagg aagggagaaa
    22441 gctcattcat caagagcaac aagctataga aagctggaaa atcaagtatc ttgtaaaagg
    22501 ttttagtaac aataagaaat acacggtgga attttctgat aacaaaatat ctaagtttat
    22561 ttcccaaaaa gggaaatgcg ctatcacagg aaacgaactt ttgatggaag aaattgaatg
    22621 ccatcacatt aacccatatc atttgtccaa agacgatagt tacaagaacc ttgtcattat
    22681 ctctagagaa atccatagat taatccatgc aactagtgaa gaaactattc tgaaactgct
    22741 tcggttactg aaactaaatc actatcaaat tagaaaacta aacacgtatc gaaaaaaagc
    22801 agctaatttt ccaatatcaa tcaaaatgaa ttagatagga aacaaattat attgtaatta
    22861 acgatggaac gccgtgtgcg gtgaaagtcg cacgcacggt gtggaccggg ggaaaagacg
    22921 gagataatat caaactctta cctatcggaa ttgccaccaa tggataatat ggaaggaatc
    22981 atgacggtca cagctggtag aaacatgttg tgggatctgt ttattcaatc ttatcagcaa
    23041 ctttatgcga agtatggaga acaaaacgca gcgattatca aagaaaattg tcagacacat
    23101 atttatatta tgtcgacaga tgataatacc atcgaagaat tttctaaaaa agtggggaat
    23161 aagacggttg aacaagagaa cagtaccatc aattcattag gtatgaatac tcatatcaat
    23221 cgcaatgttg attcagatcg tatcttaact cctgaaagaa tttctacttt tttagaaggt
    23281 gaaacgattg tactcgctcc tttaaaacga caagatttga aaggtcataa aatacggccg
    23341 tatcctattt ttaatcatgg ggaaacgaat cttccttatg cttatcaata tattgaagat
    23401 ttcaatccat cgtgggatat caatgatata gacatacatt gtacacatgc ggacttggat
    23461 cttaaggctt tacaaattga ttatgattat ttcctaccag atgaatatgc tagaaatctc
    23521 tatcatggac tgcatgatca attagaagaa aaaaacgaag aaaatatgtt ttataaaatc
    23581 gttcaatctc ttgagaatga gacggctaaa aaattgttaa ttcaatttta cgaagaacaa
    23641 gcagcagatc gacttcaaga atatgttgaa aagttgatca aaaataaaga aatttctgaa
    23701 atgattggga aacggttgtt attggaatct gaaaaggtgg tgaaagaatg atcattggag
    23761 gaattttttc tggcatagcc gactggtggt caggcttatt cggagaaggg gatgcaaacc
    23821 ccaaaaccgt aacgaaagtc ttacaagatt atggtaatta tctgcagtat caagatgtat
    23881 ttagttggat ttggaacact tttctgtggg gattgattaa aggattatat aatctcaata
    23941 ctttactaga aaaaaccatt tatcaaagct ttgatttaaa agacttattg aacgccgctg
    24001 gggtaaatgc actatttcaa agtttgatta gtaaggtatt ggctcttttt tgtgtcgtca
    24061 cattaattta tttaggcttg aaatttttta tgagtaaaca cccaccaaaa gtcaaaaata
    24121 tcttggttaa tttatttatg gccatgatct tgatttttgg tgggagttct ttaatcgatg
    24181 aagggttaaa tatcagtaaa agcttttacg gagacgtcac tgcagcaaat aaagcagata
    24241 aaacgggttc acctgctttt caaattattc aaaataatgt gatcgatgtc agtacattac
    24301 tagcaactga cccgaataaa gtagaatccc tgccaacaga caaaagaaat gctttaacag
    24361 cgaaaaattt taaaacagcg aatatcaatg ggattattac tcctaaacaa gctaaagaaa
    24421 tggcggataa agataagagt ggtttatcag atttacaaaa ggatcggtta agagcgttac
    24481 aataccgatt ggaactagat gataatggga aagaaattcc tgttcaaatt agtgacgaag
    24541 gcttagcaaa atatgtctat acttcagggt atcgtcgata cagtagtaaa ccaggtatta
    24601 tcttagctgg tgaatcttct ttggcggtgg cctatttatt tatcctattt acgatcgtta
    24661 cttgcattat tgagctggta tttaaaaaat tctatttagt gattgccgcg tcaacggact
    24721 ttgagacagg ccaacggatg aaaagtgcga tagaagatat ttctcaatcc ttcttgttat
    24781 tggcgtttac gattttagaa ttacgaatct atacattaat gctttcaggt atcggtgatt
    24841 tgcatgcggc aggaaagatc aatggattct tgtatgttgt tgctttaatt gtgctaacta
    24901 ttgcgctatt caaaggctct caatcggtta cgaagatttt cggtgttgat acgagtctga
    24961 aaaacggcag taattctctt cttagcatgt ttgccttagg aaatattgcg aaaaatgtgg
    25021 gtagcggagc taaaaacctt gcaagtgctg gtaagagtgg tttaagccat ttaaatgata
    25081 ttcgtaaaaa tggatttggc catcgaaaag atgttacccc tgataacggg gaagaacaat
    25141 cagacgataa agctacaact gtacctaata gtaagaaaac agtttccgaa atgttcggga
    25201 aagcgaaaaa tggtgtttct aaagccgcag aaggtcttgg ttacgtcaat gaacgtgggt
    25261 taaaaggaac agctgaagat cttacagaaa aagccaaaga caccttagaa gagaaattag
    25321 acggcacgag agctaaagaa ttggctgaag ctgtgaagaa tccatccgaa gcactagaaa
    25381 aacaaaaaga aaaagcttca gaagtcaaag aaggactaaa agatgcgtat ggtgaaggac
    25441 aagttaatgc agcagtaaaa gctaatacaa caaccgaaaa agaaaatcaa gaaggtatag
    25501 tgattccttc agtcaaagat caccaagaag cgttgcactc taatgaaaat tcgattgaag
    25561 agaaaaattc catagaagaa agaaattcag aagaaggaaa aaatggacag ttaccaaaaa
    25621 ctgatccaga acaatatcgc tataaaccta acagtgacct tgaaaatgag aagcgaattt
    25681 cagatttatc aaaagtaaat caagaagaca aagcagaaaa tgagggacag ttaccaaaaa
    25741 ctgatccaga acaatatcgg tatagatctg ttaactccga aaatgaaaaa cgcatttcag
    25801 atttaccaaa acgaaatcaa gaagtacaaa cggatgagga ttccatcgtt ctgccaaatg
    25861 ataatggaat cgaagttgga actgaaaaat caacgaaaat tggtttacct aaggcacaaa
    25921 atttaccaat gaaagatagt cgtttgaatc aattcaagga taatgatcaa agttttgttc
    25981 atcaatcacc tgcaggtact gttcaaatga aaccaagtcg tttgcctgaa aatggaaatc
    26041 tgacaactgt ttcttacaat ttatctgaaa gtggtgagac agggaatgcg tccgttcaaa
    26101 atgttgtgac aagagaagct gcaccaaaac ctattcaaaa cgttcataca ggttacaagc
    26161 cagcaaatgt ggcatttact gcaccaacaa aaataaatgt gacaagagaa acaaaaaaca
    26221 ggaacaatgc attgaaagaa caactattga gggatatcaa acaggatatc aaaccataaa
    26281 aggcctacaa gttaggcctt ttttctatgt atgaaaagga gaaatcattt atggataaat
    26341 atagtaacat gaaaaaccct ccaagattta gtggagaatg gaagtttttc gcttttttct
    26401 ttttagatct attaacgctt ggtggctgct ttttttgggc gaaaatggtc aataatcttg
    26461 tccacttacc actctttttt gcactcttga attatggctt atggattgcg atagcgttag
    26521 tgattgtttg gcgaccctat aataacccag gtcaacgaca aatttttgcg attatcgagt
    26581 ctattttttt tgcggacaag aaccattatc atgcgttaga tcctaaccga aattatcatg
    26641 gtacgtataa ggaggatgaa taaatgcgag tcaaaggaca aaattcagtt gaaaggaaat
    26701 ccattttgca gtttggaaaa ccagaagagc gctctatctt ggacttattt ccgtataaat
    26761 cctgtacaga agagggagtc ttaattacta gagaagatca ttttcaacgt tattatcgtg
    26821 tagtttctac agacgtggaa ggattaaatg aacaagagaa actagaacga atgaatcagt
    26881 tgaccaccgt catgcgtacg tatgtgccaa caattaagtt agttagtttg accacagaga
    26941 cggatctaac ggaacaaatc gtgcaaaagc ggcaattatt agataaaaat cgtatggaac
    27001 agtccttagg aagaaatcta caacgattaa aaaaatatga aaagaaatta gtcgaagaaa
    27061 tccaggaatt gaaacgagca gaacaagaac gtcctgactt aagcttcttt ttcgtcattg
    27121 aaggaaagac aatcaaggat ttacaaacca gaaaccgtca gttaatgcga tctagtggca
    27181 ttttagggtt aaaaccactc tacaaaaaag aattgatcaa gattctgtat cgaatgaaca
    27241 atatgaatga tgagtaggaa tggagaagag agaatgaaat atccgttgat atggttagaa
    27301 aaagatgttc cgaaggaaga gaccactaga aaatttcctc acactttaag cctgggtaag
    27361 ttgggaaaag ggcaatcttt taaccaagta aagaatcaaa caagaagagg tgactgtaca
    27421 tgttagaagc aattaaaaca gctttttcac cacaaaatga tcaaaaagta cttgatccat
    27481 taaagcaact aggaaatcgg gaaatcgaaa ttttaaaatc caaagggtat gatttagatt
    27541 ttttaaaaca agtgatgcca caaggtgggt taaattttga tgaagaatat gtgacgtatg
    27601 gtaatggtta ttcacgatgt gtgacagttt atcactacac aaaaaatcct acgctttttt
    27661 ggttggccaa tctcatgaac aatcctcata cagtggccac actcgatgtt agcacagatg
    27721 aaaagcaaaa agtgattgat caaatcaatc gtgccttaga tgaattaaat gatcgatcag
    27781 ataatgaacg aaaagcgact gaccgaaata aaagcgcgga agaatacctg gaactagcgg
    27841 aatatgctag aaaattgact tctaatgggg aaatttctaa gcaagtcaaa gtgagagtac
    27901 atgtttacgg aaacacgatt caagaagtag atgaacgagc gcaggaactg atcgaaaatc
    27961 tcaaagggat ggattatcgt gcggtgactt atctgcataa aaccaaacga gattggcaat
    28021 cgatgtttac catgttcgat gaacaagctg aatggttcgg aaatatcaaa gggcaatcac
    28081 taccatcgtt aaacattggc ggaggtttcc cgttccacca ccaaacgcta aaagatccag
    28141 gagggacaca atatggggaa accatgacag gcggcccatt tgtctggaat gcgacgtata
    28201 aaaatagtgt acggttgtct actaatacct tgcttctagg aatgatggga gctggtaaat
    28261 cgaccgttct taaaatgatc gcggaagccc atttagctgc aggagacttt atttggggct
    28321 ttgaaaaggg aaaagacttt attcctttct taaaggaata taacggtatt atggtgcgtt
    28381 tagacggatc tgacggaatg atcaatcctt tagagatatt tgccacacgg acgtatgatg
    28441 aagcatccag tttatatgac gatggatcag tcaaagattt gaagatcaat gaagcagcgt
    28501 cctatcaaac acacttagac aaagtggtct atcaggtaca gttagtgagt cctcagctaa
    28561 aaggaacgat gaaagcagaa tttaagacct acttaaatcg tttttatgaa gagtatggaa
    28621 cagtaccacg cggctttact tcctcaaatt cgcgttcaaa tactgatacg caagtcacag
    28681 ggaaagatcc agaagcttat ccgacgttca aagaattttt agacttttta ggacaactgg
    28741 aattaccagg tgcttcccaa gagaaaaaga atcgaaaaga agaaatggaa tccatcgtag
    28801 aatccttatg tgagacgtat ggcatgattt ttgatggtca cagtacgatt cgacaccttg
    28861 accaacaaca gttggtcttt tttgacattg actctattac aggcttagat cgaggggtac
    28921 aacaatgtca aatgtacatg gctatgacgt tgatttggaa tcaggcattg attcaaggaa
    28981 gaagacaacg acgtttactt aaagaaaaac aaatggaaga acaagacttc aaacgcttct
    29041 tggcgatgat tgatgagtgc cataatggtg cgacctgttc tgcagtgaaa agctgtgggt
    29101 tgcaagtagt ctaaaaacta ttgtaataac tcttataacg agaagtcaaa tgagtgggta
    29161 acgccacaaa gggcttccac tgatactccg acatgcaaca agtagtttat gcagaccaac
    29221 gttgtgtgaa gctcggtgaa gtcggctgaa ggataccgta aggtaaaaga aatagtgaat
    29281 accacgaaag ttctttagag gtaaagggtg tatccgataa gtcgggtgtc caaaaaaact
    29341 taatatggtg agtatgtaca aacgtactga cgaactagcg aatgtactgt ccgaaaggca
    29401 tagctcctag aaatgggaga gacagtgagc aaaaaatcac tcattgtgct aacttgtggt
    29461 tgagtaaaag tcgttgttat gaaagaccat gctgcgttac aggcgtagga gaagttaggg
    29521 ggcaaaagct agcatctaag ttaaggcatg tggatagata taagggaaca ggggaagcca
    29581 tcaacatgga gagtgcatac tcgatgaagt ggtagtaaga aatatgtgaa tgacaaataa
    29641 cttactttag tgatggtgaa agtagagtca cgactgatga aggttctgta atggaactgg
    29701 aggaacaggc tcgattcgtc tgtaaaagtc atgaaacccg ttcaaccatg ggattctcgt
    29761 atgactaaaa aggtcacgag ccaattggag cgtgataaac catgacaaaa gaaacaagtc
    29821 caaaagatag gaagttgcgg catgcagaat attatggcat gacggaaatc ttcgataaga
    29881 tatactccaa aagtttgaag ggagataatt tcaagaatct aatgcagatt atcatttctg
    29941 ataacaacat tgtcctagca tatcgtaata tcaagagaaa tcacggtagt gtgacaagag
    30001 gagaagatgg agtaacgatt aaagatattg aaaatctcaa ccgtaatgaa ttcgtagaaa
    30061 ttgttaggaa gcgattcgca cattataacc ctcggaaagt aaggcgtgta gaaattccta
    30121 aatataatgg taaattaaga ccgttgggta ttccatcaat atgggataga atcgcgcagc
    30181 aatgcatctt acaagtatta gaaccaatat gtgaagcaaa attcaataat cacagctatg
    30241 gtttccgccc aaatagatca gcagaacacg caatagcaga ttgtatggcc cgaatgaatc
    30301 aaagtcacat ggaatatgtg gtagatgtag atatcaaagg tttcttcgac gaagtcaatc
    30361 atactaaact catgagacaa atctggtcta tgggtatacg agacaaacag cttctcttaa
    30421 tcattaggaa aatgttaaga gcacccgtag tacttccaaa tgggaagttg atatacccaa
    30481 caaaaggaac accacaaggc ggaatactta gcccattact tgcgaacatc aatctcaacg
    30541 aatttgactg gtggatagca aatcagtggg aggaaaaaga tgccaaagag ctaaaacatc
    30601 attttaggaa aaatggagct tgggataaag gtaatatcta tcacaagctc agaaagagta
    30661 caactctaaa agaaatatac ctagtgagat acgcagatga ttttaaaatt ttctgtagaa
    30721 attataatga agcgaaaaaa gttttctatg caactaaaat gtggttacag gagcgtctaa
    30781 agttaccaat atctgaagaa aagtcaaaaa tcacaaatct ttcaaaagaa gaaagtgaat
    30841 ttttaggctt tacgatgaaa ttagtgacca aaggtaacaa aaaggttgtt aatacgcata
    30901 taggtacaaa agcacaaagc atgattaaag tgaaactaaa aaaacaaatc aaacgaattc
    30961 aaaaaagtcc taatagcaaa gataccttta tctatattgg agtctataac agtatggtta
    31021 ttgggattca taattacttc aaaattgcga ctcattgtag tgtagcaatg cgaaaaattg
    31081 caagagaact cagaccaagt tttgaaatac gactacgaga acaaggaatc tcaaaagaag
    31141 gacaatacgg aaagtacgaa ggatacaagc cttacctacg gtcaggacaa atacgatata
    31201 taagagggtt tccaatatta ccagtagggt atattcaaca cagacatccg atgtgtaaaa
    31261 aaagaaatat taataaatac accgaagaag gtagggaagc cattcataag aagcaacaaa
    31321 ccgtagaaga atggaagata tcgtggttgt gtagcaatcc agtgcttagt aagagagcaa
    31381 cgattgaatt tgcggacaat cgaatttcaa aattcatcgc tcaaaaggga agatgtgcag
    31441 taacaggtga ggagcttatc ttatctgaaa tgcattgtca tcatattatc ccttatcatg
    31501 aaagcaaaag tgatagctat gaaaacctag tgattgttac tgaggaggtt catcgggtaa
    31561 tacacgctac acaaagtgaa acgattgagg aacttctaaa atatctaaaa ttaaatccaa
    31621 aacaaaaaga aaaactcaat gagttgagat taaaagttgg taacgaagaa atatcttaat
    31681 aaatatttgt aggacgggaa aacagaatgt cttttataga cgagggaacg ccgtatgcgg
    31741 tgaaagtcgc acgtacggtg tggactgggg gaaaagacgg agataatatc aaactcttac
    31801 ctatcagtat cgattaatcc agattttatt gaaacggtaa attatgtcac aaactttcaa
    31861 cgagaaatgc gtaaagtaga agcaatgact gttttagcta cacaatcccc acaagaaatg
    31921 gtgccagaaa atatgtcttc tgataacttc tcgaaactga agaaagtctt tgaattttct
    31981 tctacgaaga tctttatgcg tatggatgaa tctattttac gtcatataga aggattagtt
    32041 ggtaaatcaa tgacgaactc agaactagaa tccattcctc aacaaaatca aggagacgct
    32101 gtgatcaatt ttggctcaaa agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa
    32161 ttgaaattgt ttgatggtgg aaagtaactt cttgtatttt ggtgtataca agtatatact
    32221 aatgtgtgag agaaggaggg attccatgtt agtaaaagaa atcgaaatga aaaaatgggg
    32281 aaattcacaa ggtattcgtt ttggaaaaga agaattgtca gttctaggag aaactaatac
    32341 tgaaaattta aaattcgaaa tggtggtaac agaaggaaaa attgttttaa ctcctaaaaa
    32401 taaaaagcca gaaactttag atgaattgtt cgccaattat gaaggagaac ccttaggaaa
    32461 agaagacaaa tatgaatggg gaaatatgca aggtagggag atcatttaat gaaaaagaac
    32521 tatcatgatt tatcgcaagg agatcttgtt tatattgatt taaatcctac caaaggacat
    32581 gaacaacggg gaaaacgacc atgtattatt ttatctaaac ctaataaata tttgaactat
    32641 atgattggtg tcgcaccgat aacaacaaaa gcgaagcctt ttcctgtaca tgttgatttg
    32701 aatggtacgc aaaaaataaa aggacaaatt cttttggaac accatcgaat gattgacatt
    32761 gagagtagag gttttcagtt tgtggaagct gtgccaaagg aaattttaga agaatgtatt
    32821 gaaaaaatta aattatttta ttaaaagcag cgaagaataa ttattatttc ttcgcttttt
    32881 tgttgtttaa aattaaaaag ttaggagtac tgactatatg gaaaatgata caaatatagt
    32941 tatggaacat ttgaagcgtc gtgcaaagcg acgcttattt ttgtggttgt ttggtacttc
    33001 tgcaggtttg attactattt tgatcactgt gttcgtaacc ctttttctaa tacttgcggc
    33061 gggttcgatt gataattcgg attccgattc aagtagtggt ggcgaagctt ttacaggaga
    33121 gtattcggaa ggcttaccga tttataaaga aatcaaagga agaggccctt tttctgatga
    33181 gattgcgcaa tatgccgtag gtgcagcagt gaaatataaa ttattaccaa gtgtgattct
    33241 ttcgcaatac ggttatgaat cagcgtttgg tacgtcggcg tccgcaagaa atgatctcaa
    33301 ctattttggg attacttggt ttgatggttg tctgtttcct aaaggaactg cacgaggaat
    33361 tggtggcatt gaagggggct ggtacatgaa gtttcccaac tcaaaagctg cattctccta
    33421 ttacggcttt atggtagcca cacaatcaaa ttttaatgca tgtgtaggaa ataaaagccc
    33481 tggcgcaagc ttattgatct taggacgagg tggttatgcc gctgcaggaa ttactgaaga
    33541 tagtccgtat tatacaggtt gtatgtcaat tatcacttct aataaattaa ccgaatatga
    33601 tgaattcgcc atcaaacatt ggggtgaagg tggcaataac aatggcacaa ttactggtga
    33661 atggacgaat ccattccctg gcagcagttt agataaaagt tccttcagcg gtggtcaatt
    33721 atttggaacg aatccaggcg gtgaattccg tccgaacggc ttccatgatg gattagattt
    33781 tggttcagtt gatcatccag gaagtgagat tcatgcggtt catggcggaa aagtcgtgta
    33841 cgttggcaat cctggtattt caggtttggg cgcgtgtgtg atcgtgatta attacgatgg
    33901 cttgaatatg gtgtatcaag aatttgcaaa tagtacagga aattctcgag tgaaagtagg
    33961 cgatcaagtg aaagttggtc aagtaattgg gatacgagat acagcacact tgcatttagg
    34021 atttactcga atggattggc gtcaagcaca aggacatgca ttcattgatg atggtacatg
    34081 gatcgatccg ttaccatttt tgaatagcag taaaaaatag atcaggagaa aaaatatgga
    34141 aaataaaacg ttaaaaatcg tcttaacagc tgcaattagc gttagtttaa tcggcaatat
    34201 tgcgttgttt tggcagctga aagaggaaca agcagcaaat acctataaaa ttgaagaagt
    34261 ggctaaaaac gcgtctgaga agctcaaaaa aaattcctct gaggcacagg cgaagatcga
    34321 caagttaaat caaaccatca atgagaaaaa ccaagaaatc gatcagctga agcaacaaga
    34381 tggcacaaaa gcaaaagagg aagtaactga agcacaaaga aagacggcag aagagttcgg
    34441 tcaattggcc attgataaat cattaagcag aaatgaatta acggaaaaac taaaagatgt
    34501 cgcaacccaa gaagtgatcg acaaattaag tcctacagac gatgatcacc aacatgatga
    34561 ttacggaagt tactccttta cattaggtga cgtgcaaact tacgctcaaa caagcagtgt
    34621 aaaagaggaa caaaattttg tcgtatttgt tgattataca atcggcaatc cgcaattcaa
    34681 agatgtcaaa ccacaaaaaa taaaaggtgg attaactgtc actgaaaaac aagtagatgg
    34741 tcaatggaaa gtcatagact ttagttattt cactcgttag gaggaagaaa atgagtaaga
    34801 aaaaaggaga aagacaacgt ttcaaaaaac gaaaaagtta tcttcaatgg ctgggaatct
    34861 ttatgattct cggctttttg attcttgcta gtccgattta cacgcatcag aaggtagaca
    34921 taccagatga agtaagcacg aacgcctttt taaacacgaa ggaactaacg atggtttcaa
    34981 aagaaaaagg agcgaaccag caattagttt ttgaatttgc aatcgacgat gaagatcaaa
    35041 gcttattaaa agaactggct aatcttaatt atcgcgtaga agtaaagaca gctaaagggg
    35101 attatcaagc aatacgagcc aaagtgatca aggtgtctga tgattatttt gcagtgaagc
    35161 taacgcatgt accagaagaa tatatcgcca tgcgtttaac cattattcct gaaaaaattg
    35221 atccaaaagt ggatatgcaa gaaccacaag atctgattta ttacgtgcac gaagataagg
    35281 ttaaagatca agtgaaagat gaagattatg aacaacacgc gatcaattac aaagtgaaag
    35341 gatacaagaa agaacaaaaa gcagctcaaa aacaaatgga atctttccaa gcaaccattg
    35401 atttgaatga agaattagtg aagaagctaa aagatcaatt gccttatcaa gtcgcagatg
    35461 atcaggaaaa tactgaaaac aagattaata gctaccagca agaaattgaa acatcgaaaa
    35521 cgcaaatgaa agatcaagaa gagatcattc aaaaacttca agaaaaaatt gatcgtatga
    35581 caaaagaaaa gatttagaag gacaggtgga gtgaaaaaat gaagcgaaca aacttggctg
    35641 acaaagatac tttcgctgag cagaaagtat tgattaaagc ctatctcaaa gttgtaaaag
    35701 ctaaagaaat atgtcgagaa gtgaatttat ctaatacaac aatatctgag ttgaagaatg
    35761 gtcgaaagaa tttagatact ttaaaattca gatcatttga agctttgtat ttagctgcta
    35821 aaaaatattt tacagctgat aacaaataaa aaacaggagt attttatgtg aaaaaagtat
    35881 ataaaaaatg cttatgaatc agctatatca ccttaaccat ttgttaatga gatgggagaa
    35941 aacattaacc acgattctaa cgcaaacatc aagcacataa aacatttaac actcctcctt
    36001 tctggctgaa gatttcaacc aaacaggaag acagcgtatc aattatagca tacacttttt
    36061 cttaaattca tttttcatat gacaaaatat ttccttctaa tcgacaaagt tagaaggatt
    36121 ttttattgtc taaatacaca aataacctta atttataaag agcataagga aacgtgtacc
    36181 cactttcaaa ataaagtggg tagataggct gtgcctatca cgtttctgaa aaaaataaat
    36241 gaccccaaaa ttttcaaatt atgtgtaggt ttatgggtag caaaaatatg aatgtgggta
    36301 gcacaaaagt tcatttgtgg gtagtaaaat ttaaatatgt gtagcaatgt gtgtagctac
    36361 acacattgct acacacgtta taacatatag tcaaaaggag atatttatgg aagtaaaaat
    36421 aagagatatt gatgaaaaaa cgattcaaag aattgaccga agatgtattg aattaagtga
    36481 acgtactggg actaaatgga gccgaaatcg atacctaaaa gttttgatcg aaaatgattt
    36541 tgatcacgct cttctggatt ataaaaaaga tcaatttgat cggttgttag aaaaatttgt
    36601 ggatattcaa acttataata cgaaaatttt agaagaatat attgcaacaa ataatcaatt
    36661 aatcgccttg ttaattgaac agtaaaaata atattgtgaa tttataaaag gaggaaatca
    36721 actttggcga aagcaacaag aaaacatatt tatctttatg atatgcatat cgaagtactt
    36781 gatgagataa tttctactca tgacgatata tccaattata gtgaagcagt tagacatttg
    36841 tgtatgatgt atgatcccaa aactgaagaa aagataagtc ccagtcaaat caaactaaat
    36901 gcaattggaa aagaagtttc tattttaact gaaatggttt cggagtttgc agatcttcat
    36961 ttaaaagata caggaatatt aattggtaca aattcaactg tttatcaaga agcgaaagag
    37021 cgtgtggaag gcaagataaa agcaaatcaa acgaagaaat attctcctaa gataaagaaa
    37081 acaataagcg aatcagtgac tacaaaaagt gaagtatttg atccaacaag gtttttaaaa
    37141 cgataaaaat tagaaggaga acgtgatgag taaatcacct gcagtcattc tcacttgtca
    37201 atttaccttg cccaataaaa aatctttttc aacatacatt gattatatga caagagaaaa
    37261 agcgctggaa gaaatggaac ggcgcacgct cgaagaagaa caggaactgc aacgaatcaa
    37321 gaatgcttta gaggattttt atattcctga aggagaaact ttttcggaga gtaagacgga
    37381 taaagaattc agtgaaacgt cgaatgaagc gcaatcgttg atggaatatg gaatcaattt
    37441 tgacaagtta gaggaacaag attttaccaa atatctttct tatatgacgc gtcactatgc
    37501 gttagaacaa aaaaaggaac taacggaaag ggaaaaaata gaatatcaac gtttgaatca
    37561 agcaatggaa aaatatcaag cagaaccaca caaaaaaact tcaggaactc ttcctggagt
    37621 tttttctata tcttcagacg aagtaaaagg aagtgatctg aaggagatta agcagatctt
    37681 ccaaagaggg caacaaaaag gctcaatcat ttatcaagat gttgtttctc atgataattc
    37741 gtatcttgaa aaaataggat tgtacgatcc caaaacagat actttagatg aagttggact
    37801 aaaagctgct ggaaggaaaa tgatggagac gttgtttgag aaagaaaaac tgaatgatac
    37861 gggatattgg atggctacca ttcaccgtaa cactaagcat attcatattc attttgcagt
    37921 tgttgaaaaa gaaaatacgc gtaaaccata cactgaggtc gaaaatggtg tgagttatat
    37981 cgtaccgaaa ggaaagagaa gacaagcaac attagacgca atgaagacca attatgtgca
    38041 tgaattagaa cgtttttctt atgaaaagga tcgaatgata ggcatggaga aacgaaattt
    38101 attaacgcgg aaaagtgatt tgcgtaacag cttaacaaaa gtggtaaaag agccagtacg
    38161 ttatgatcga cacgcaatga acttattaaa tgaagtatat aaaaccttac ctgacaaacg
    38221 ttcggaatgg aattatgggg atgaaaatcg aactaaactt tcaccataca caagagagaa
    38281 actcgacgag ttaacccaat atgtgttaac aaaagaacct gaataccaag aatatataca
    38341 gatttcaaaa gcattgaaag aagaagcaaa aagtctttat ggggaaagca agagagaatc
    38401 aaaggatgca gagaaaaatg ctctctttga tttaaaaaag cgcacaggaa atgccatcct
    38461 aacagagctg aagagacagg atagtcaaat aaaaccatta atagaaagtg ttgatcagac
    38521 gcaatctatt tacaatgaac gatcctttcg aacgcttaaa caattgccaa cgaatgaata
    38581 caaatatagt tacgaagaat tcatgaagcg caggaaacaa ttccaacaaa gagttgtcac
    38641 gcagcggagt ttgcgtcaat taaatcgaac gattaatgcc catgaagaaa aataccacgc
    38701 aagtaaagca tacgaagagc aacaacgaag aatccaaatg gaacaagaaa gacagtaaag
    38761 acagtaaaga cagtaggagg aatagcaatg aaacaatatt tagatcaatg gaaagttata
    38821 gaaggatcat taagagaaga acgaatcgaa caacttcccg attgtttaga aaaagagcat
    38881 ttgtttcaga taagagaaat gttgataaac gaacagtttg atccaaatca atttttagtc
    38941 gttgagtacc cagctactgg tgtgtactgt tgtaatcatg tgaagggtga aaaatatttt
    39001 atcattcaag aatatgaggg caagttagcg ccttattata ctacttggga aatgaatgaa
    39061 gaggggatca ataacttccc gtgtaaaagc attgaagagt ctatttcact cacagaatgt
    39121 tagttgttaa gtgaataaaa gaagtaaaag agtcctgaac gtgattgtcc aggactcttt
    39181 tttttcactg aattgttttc cgccaattca ttgagtggtg cgatttccgt ctacattata
    39241 tcaaaagaaa ggaggaagaa gaaatggctt attcaacgat tggagttgtt gttgaaaaaa
    39301 gcagagacaa tcttgttttt gtgacagaaa ttcaaacagg cagagctttt gtagtcacag
    39361 acaaagcggc aaaagcatat caaagtggcg atattttaac gttaaatctg actacgaaga
    39421 cgttcgtcga tgcggcagaa gattatcc
//
LOCUS       DAIGUC010000024        36703 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.024, whole genome shotgun sequence.
ACCESSION   DAIGUC010000024 DAIGUC010000000
VERSION     DAIGUC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.024"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            647..964
                     /locus_tag="NOB46_001309"
     CDS             647..964
                     /locus_tag="NOB46_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI1058252.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="NOB46_001310"
     CDS             complement(1055..1420)
                     /locus_tag="NOB46_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058253.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="NOB46_001311"
     CDS             1628..2110
                     /locus_tag="NOB46_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058254.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="NOB46_001312"
     CDS             2307..3197
                     /locus_tag="NOB46_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HCI1058255.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..4758)
                     /locus_tag="NOB46_001313"
     CDS             complement(3484..4758)
                     /locus_tag="NOB46_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1058256.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5031..7502
                     /locus_tag="NOB46_001314"
     CDS             5031..7502
                     /locus_tag="NOB46_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI1058257.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7605..9341)
                     /locus_tag="NOB46_001315"
     CDS             complement(7605..9341)
                     /locus_tag="NOB46_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCI1058258.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9338..10042)
                     /locus_tag="NOB46_001316"
     CDS             complement(9338..10042)
                     /locus_tag="NOB46_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1058259.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10173..10676
                     /locus_tag="NOB46_001317"
     CDS             10173..10676
                     /locus_tag="NOB46_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCI1058260.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10636..10974
                     /locus_tag="NOB46_001318"
     CDS             10636..10974
                     /locus_tag="NOB46_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCI1058261.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10995..12413
                     /gene="ffh"
                     /locus_tag="NOB46_001319"
     CDS             10995..12413
                     /gene="ffh"
                     /locus_tag="NOB46_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCI1058262.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12525..13103
                     /locus_tag="NOB46_001320"
     CDS             12525..13103
                     /locus_tag="NOB46_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCI1058263.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13055..13627
                     /locus_tag="NOB46_001321"
     CDS             13055..13627
                     /locus_tag="NOB46_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI1058264.1"
                     /translation="MFPQRRGRTYRQKGRIKHAKIIFYGAISLDGYLATKTDDLQWLF
                     DTPTGKQTTYEAFYETIDTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPD
                     AEVVNEDPVAFLKNLQMTEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIP
                     LFQKGTYEARFEMLDTTRFGEFIELHYVRK"
     gene            complement(13706..14260)
                     /locus_tag="NOB46_001322"
     CDS             complement(13706..14260)
                     /locus_tag="NOB46_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI1058265.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14513..14788
                     /gene="rpsP"
                     /locus_tag="NOB46_001323"
     CDS             14513..14788
                     /gene="rpsP"
                     /locus_tag="NOB46_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCI1058266.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14800..15051
                     /locus_tag="NOB46_001324"
     CDS             14800..15051
                     /locus_tag="NOB46_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCI1058267.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15176..15967
                     /locus_tag="NOB46_001325"
     CDS             15176..15967
                     /locus_tag="NOB46_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058268.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16137..16658
                     /gene="rimM"
                     /locus_tag="NOB46_001326"
     CDS             16137..16658
                     /gene="rimM"
                     /locus_tag="NOB46_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCI1058269.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16648..17409
                     /gene="trmD"
                     /locus_tag="NOB46_001327"
     CDS             16648..17409
                     /gene="trmD"
                     /locus_tag="NOB46_001327"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCI1058270.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17545..17892
                     /gene="rplS"
                     /locus_tag="NOB46_001328"
     CDS             17545..17892
                     /gene="rplS"
                     /locus_tag="NOB46_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCI1058271.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            18150..18443
                     /locus_tag="NOB46_001329"
     CDS             18150..18443
                     /locus_tag="NOB46_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCI1058272.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            19286..21613
                     /locus_tag="NOB46_001330"
     CDS             19286..21613
                     /locus_tag="NOB46_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1058273.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            21739..22068
                     /locus_tag="NOB46_001331"
     CDS             21739..22068
                     /locus_tag="NOB46_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCI1058274.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            22108..23112
                     /locus_tag="NOB46_001332"
     CDS             22108..23112
                     /locus_tag="NOB46_001332"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI1058275.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            23109..24538
                     /locus_tag="NOB46_001333"
                     /pseudo
     CDS             23109..24538
                     /locus_tag="NOB46_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            24744..25916
                     /locus_tag="NOB46_001334"
     CDS             24744..25916
                     /locus_tag="NOB46_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1058276.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(26078..26533)
                     /locus_tag="NOB46_001335"
     CDS             complement(26078..26533)
                     /locus_tag="NOB46_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058277.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            27123..27545
                     /locus_tag="NOB46_001336"
     CDS             27123..27545
                     /locus_tag="NOB46_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058278.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(27711..28904)
                     /locus_tag="NOB46_001337"
     CDS             complement(27711..28904)
                     /locus_tag="NOB46_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1058279.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            29128..29505
                     /locus_tag="NOB46_001338"
     CDS             29128..29505
                     /locus_tag="NOB46_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1058280.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            29493..29831
                     /locus_tag="NOB46_001339"
     CDS             29493..29831
                     /locus_tag="NOB46_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1058281.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            29965..30408
                     /locus_tag="NOB46_001340"
     CDS             29965..30408
                     /locus_tag="NOB46_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI1058282.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            30670..31485
                     /locus_tag="NOB46_001341"
     CDS             30670..31485
                     /locus_tag="NOB46_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058283.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            31495..32157
                     /locus_tag="NOB46_001342"
     CDS             31495..32157
                     /locus_tag="NOB46_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI1058284.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            32362..34026
                     /gene="alsS"
                     /locus_tag="NOB46_001343"
     CDS             32362..34026
                     /gene="alsS"
                     /locus_tag="NOB46_001343"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HCI1058285.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            34039..34749
                     /gene="budA"
                     /locus_tag="NOB46_001344"
     CDS             34039..34749
                     /gene="budA"
                     /locus_tag="NOB46_001344"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HCI1058286.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            34879..35376
                     /locus_tag="NOB46_001345"
     CDS             34879..35376
                     /locus_tag="NOB46_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCI1058287.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            35561..35821
                     /locus_tag="NOB46_001346"
     CDS             35561..35821
                     /locus_tag="NOB46_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058288.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(36183..36422)
                     /locus_tag="NOB46_001347"
     CDS             complement(36183..36422)
                     /locus_tag="NOB46_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058289.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT        12338 a         6418 c         7304 g        10643 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc atttgaaata cccgattggt agcaatggaa
     3661 gatcgtgaat ttctttttaa acgactgagg taacgtagat gaaattgttt taagggtttc
     3721 ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt aataattgac aaaaatgata
     3781 cgcagttcgc aattcttcgt tgtagcttaa cagctcatca acgatttctg tttgactaat
     3841 tggtcgttta aacagtcgat gataatgccg tttgagtggc tcccatgtcg tggaatcttt
     3901 gagtaagagt ttccaatatc gcttgagccg acggtacttc ttctgatttt cagagtgtga
     3961 ggttcgaaaa cgattcatga tctggacacg taattgattg aagctgcgat tgatgtgttg
     4021 gacaatatga aagcggtcag ttacgatctc cgcatttgga aagactgttt taagcaactg
     4081 acaatagctg gcattcatgt ccatcactag gtacttgacc tttaaacggg cctttctagg
     4141 aaagcgcagg aagtattgag ttagtttgta aagtctgcga tcttcaagga tcgtaaatag
     4201 ctgattggtt gtcccatcaa cacaaataaa actcatggaa ccagaaacag aattcattga
     4261 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtggct ggtaatgctt
     4321 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
     4381 tagtttacgt gattgatttt cgtacagttc catgagaatc gcctgcttca gttcctttgt
     4441 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
     4501 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaacat
     4561 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
     4621 ataggaagaa gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
     4681 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
     4741 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
     4801 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
     4861 ccttcgattt tccaccaaca caaaatatta tagaaccctt tttttttgct atatgacagg
     4921 aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc catatctgtt ctatactgga
     4981 taggagaagt ttggaaatat ccagaaaacg aaatcaatcg aggtagccac atgaagaata
     5041 aatggataaa tcgaagtaaa aaaaagaaag taacacaaag atcatcagat aaagtcatcc
     5101 gtctttttcc atcgtataaa gaaggattaa cggcagatca agtcaaggaa cgaatagaaa
     5161 aaggtgcagc aaataattca gtcgatccca cattcaaaac aaatcagcaa atcgtattgg
     5221 aaaacatatt tacgtatttc aatttgatct ttcttatctt agccattttg ctttgtttag
     5281 tagaatccta taagaacttg acttttttac cagttatcat agccaataca ggaatcgcca
     5341 tttttcagga aattcgatcc aaaaagatct tggacgaact aaatgtttta aatacagcaa
     5401 aagtcaatgt catacgagac gggatagaac aaacaataga tatagaagac cttgtaatag
     5461 atgacattgt tattttagag actggatatc aaattccagc agatgcagag gtcgtggaag
     5521 ggaaactgca agttaatgag gctttattga caggcgaagc agatgaaata accaaagaaa
     5581 taggtgatcc attaatgtcc ggcagtttca ttgtttccgg aaaagcttac gcccgattag
     5641 acaaagttgg agcagattcg tatatttccc agctgacagt caaagccaag acaatgggag
     5701 aaggagaaca gtcggagatg attgcttctc ttaatcaatt gatcaaatgg attgggatca
     5761 tcattattcc tatcggtatc ctgctttttt ctcaaagtta cttttttaat ggaaacacga
     5821 tcaaagaaag tgtcgttgca atggaagcag cattgatcgg tatgatacct gaaggactgt
     5881 acttgctgac gacgattgca ttagcattaa gtgcgactaa actagcaaag caaagagttc
     5941 ttttacacaa tatgaaaagc attgagacat tggcaagggt aaatgtcctt tgtgtagata
     6001 aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa aatgatcgtc tctaaaaaac
     6061 aagaaataat cagtcagtca gatcaattgg aagcatgcat tgctgactat gcaaaagcga
     6121 tggcaggaga caatgcaaca atggaagctg ttaaagcata ttttacaaaa accactgatc
     6181 aatcctatca ccatgttatt cctttttctt ctgtccaaaa attcagcagt gtagcgttgg
     6241 cagacaaggt gtatgtttta ggagcgcccg aaatggtttt gcgcgatcaa ttgccggaat
     6301 atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg cgtgttggtc tttggtgtgt
     6361 acgatgggat tcttgaagaa ccagtattga cagaagcagt cacaccatta ggctatattc
     6421 tgattgctaa tcctatcaga aaagaagcaa gagccacatt tgattacttc aaaaaacagc
     6481 aagtagccat caaagtgatt tctggagata atccgctcac cgtatccaat gtagctgtcc
     6541 aagcagggat ttcacatgct gatcagtacg ttgatgcatc taaattatca gaagaagaat
     6601 atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt caagccagaa caaaagaaaa
     6661 tcttcgttca attgataaag cgtaacaata cagtagctat gacaggtgat ggcgtgaatg
     6721 atattctagc catgaaagaa gcagactgca gtatagcgat ggcttccgga aatgaagccg
     6781 ccatgcaggc ctcacaagtg gtcttacttg attctgactt ttcacgcatg ccagaagttg
     6841 ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc agccagcttg tttttagtga
     6901 agaatatttt ctcctttttg ctctcactgt tttcagtgat ctttgctctg acctatcctt
     6961 tagaaccatc acaaatcaca ttgattagtt tgtttactat cggacttcca tctttcttgc
     7021 ttgctctaga agaaaacaaa aagcgaatca gagggaaatt catcatgaat gtgatggaaa
     7081 aagctgtgcc aggtggacta acagatatga tcgtagtcgg tgcgttggtg atctgcgggg
     7141 tgactttgaa tctaaataaa acagatgttt ctacagcatc taccatgctt ttgattgcag
     7201 tagggttcct cgttctctat aaaatctgtt caccgctgaa taaattcaga agtcagatca
     7261 ttcttttctg tgctagcggt aacttttttt cggtcatctt tttgcataag ctgttttcaa
     7321 tcaccggtat ctcagctgta tcacttttgc tgttgagcat tctatttttc tcggcagatt
     7381 cgatttttag gcatttgacc acattggtag aatatttgtt tgaacgtaaa aatgaaaaag
     7441 agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc gatatttaaa cgagaaaatt
     7501 gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca ctcgtgtatc tttcgaagca
     7561 ggatgagtca tccaacttta aaacgcacga gcagttgctc ttttttacat tttcggaatg
     7621 gtaacggtga aagtcgaacc tgttccaaga tgactgtcta cagtaatcgt accattaagg
     7681 agttgcacgt agtcttttac aatcgctaac cctaatccgg tcccgcctga atgtcggctt
     7741 cgcgccttgt ctacgcggta aaaacgctca aagatccgtt cctgatcctc aatgtcgata
     7801 cctataccaa agtcttggac agaaaacgat agatcatctg ttgcctgata gcggataata
     7861 atctcgctgt cgctttttga atattggaca gcattttcaa tcagattttt gataattgga
     7921 taaaggatat ctgttttagt agtaaatggt tcgttctttc caatcaatcg aatcgtcaac
     7981 cgtttctttt cgatgattgg ctgataattt tgaacgattt gctggaaata aggttctgta
     8041 taaattgtct ggatctcgta agaattctcg ccatcttttg acagctggat gatttcccga
     8101 atcagtttat ctaaccggat cgcatctttt tgcatgatct caagaaaaga agtcagagtt
     8161 tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa aaccaatcag tgaagtcaca
     8221 ggagttttta attcgtgaga gacgttgcca acgaaatcct tttgtagctt ttctaaacgt
     8281 cgcactttcg ttaagtcata cgccacccct agaatctgtc cggtaccttc tgaattagta
     8341 aagtagcgca aactcaagtc taatgtctgc cgaccttctg taagggtgat ctcctgatgg
     8401 atcagcggat gctcaggagt cacttgatga atcagctgaa tgagttttgg ctcttgaatg
     8461 acttctgtgt accgctgttc aggttgatag cttaccacgt ttaaatgtag ctgcatcttt
     8521 ggattaagca gtagtaaacg agaatcagca tcatcaatca ggaatacgcc aatcatcagt
     8581 tcgttcagta acgtatataa ttgctcttct gtggtagtac acgcccgata catcttactc
     8641 atttgttcgc tcaacgcatt aatcgtctga tacaattctt cccattgatc gggtgtttgc
     8701 atgattactt ccgcctgatt aggattttgc accatttttt ttagtacggg cagcacggtt
     8761 ttcaatggct ggtttttttg atagatcaga taatagatca ttcctgcaag aacaaggaag
     8821 aaagacagaa agaagaaaaa gacccaacgg cgaaaactct cagttctcgg taaaaaaacg
     8881 cttgtcggtt ctgcgatacg taaaatggct tctaactggc cacttttttt gactggtaat
     8941 gcgacatata aaagatcctc attcaaagta gtacttttgc gcaaagcgct acctaggttc
     9001 ccaccattca atacggcttt gatttcggga cgggagtttc gctgttcatt caatgtttca
     9061 ttgtttgtgt caaataagat ctttccagta gcatccatta aagtaatccg ttcgttcgac
     9121 tgatggacga attcttccaa agcagttttg ttttgcgctg cttggaggtt ttcgacatct
     9181 aattgccgga tcagcagttg tgcttttttt gtcaggtagc tttcttgctg ttccacgatc
     9241 tgctgttgaa aataatggga aatcaattgc cagccaccaa aaaacaaact aactaaaaga
     9301 ataagaaaga agagacgttc ataaattttt ttccatttca tcgtttgggt tcctgaaact
     9361 tatagccaaa tcctctaata gtcaccaagt actttgggtg ttttggatct cgctcgattt
     9421 tttctcgcaa atgactaacg tgtacatcta cgattcggct ttgtcctgcg aagtcaaaat
     9481 tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg gtcttttcgt ttcatgaaat
     9541 aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag atggtcgtct acggtcactt
     9601 gataattggt caaatcagca gtgatttgtc caatcgatag atattcaggc tcagcttcat
     9661 cttttgattg cttacgaggt tcaattcgtc tgaatattgc tttcatacgg gctaatactt
     9721 cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc tatttctagg ccaatgatcc
     9781 gatccacttg gtcatcttta gccgtcagca tcaaaatcgg tgtttcattt ttttcttgac
     9841 gcagccgctg agtgatctcc atgccatcca tcgttggaag catcacatct aaaatgatga
     9901 aatcaaatga ttgttctaat gctaattcta atccttcgcc tccatctgtg gcactggtta
     9961 ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt tacaatagaa ggttcatcat
    10021 caacaactag tatttttttc attcaaatct cctttaaata ggtttcattc tgtttatatt
    10081 ttagcataga atcagtacaa agggctattt tacaaaagaa ataaatggta taataggaag
    10141 gcactttgct gaatagaaag gaagagcagt caatgattgg aatcagtgca tgtttaggcg
    10201 gtctggcctg tcgctatgat ggacagaaaa aagaagtacc agaattgatg gaactagttg
    10261 aaactggaga agctgtcatg gtctgtccag aagtgatcgg cggattacca attcctagag
    10321 atcccgctga aatcattggt ggaaatggat tcgatgtgtg gaaagatcaa gcaaaagtat
    10381 ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa tggcgcgatc aaagcctatc
    10441 aaaaattgca ggaaaaacac attgatctag tcatcatgaa ggaaaaaagc ccttcatgcg
    10501 gaacccattc gatttatgac ggaagttttt ccggaataaa aaaaaatggt gccggagtgg
    10561 ctactgctta ttttattcag caaaaaatga ctgtgctctc tgatgaagaa tggctgaaaa
    10621 ctagaggtga gcagaatgga aatcgaaaag accaatcgaa tgaacgcgct ctttgaattt
    10681 tattcgacct tattgacaga aaaacaaatg aactacatgg aattatatta tgcagatgat
    10741 ttttcattag gtgagatcgc ggaagaatac gaagtaagcc gacaagcagt atatgacaat
    10801 atcaagcgga caagcaagat cttggaggat tatgaaaaaa aactccatct tttttctaat
    10861 tatattgttc gagaacaggt attggaaaat atgactgcat atattacaga taagtacccg
    10921 gaagataaaa aactacttga atatgtacag caaattcaag caatcgaaga ataaataaaa
    10981 ggaatgaaga aaatatggca tttgaaagct taactgaacg tctccagcag gcgatgggaa
    11041 aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa agaaatgatg cgggaaatcc
    11101 gccttgcctt actagaagcc gatgttaact tgcaagtagt caaagatttt actaagcgcg
    11161 tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt atcacctgca caacaaatcg
    11221 taaaaatcgt tgatgaagaa ttgacgatca cacttggttc tgaaacagca gagttaaata
    11281 aatcaccaaa aataccaact gttatcatga tggctggtct tcaaggggca ggtaaaacga
    11341 cctttactgg taaattagcc aattatttaa agaaaaatga aaatgctcgt ccgctcctaa
    11401 tcgcagggga cgtatatcga ccagctgcga tcgaccaatt gaaagtatta ggtcaacagc
    11461 tagacgttcc tgtatttgat atgggaactg aagtcagccc ggtagagatc gtccgtcaag
    11521 ggatggagtt agcaaaagaa aagaaaaacg actatgtatt gatcgatacg gcaggacgtc
    11581 tgcatatcga tgaaacattg atggatgagt tgaaacaaat caaagaattg acgcaaccaa
    11641 atgagatttt gcttgttgtc gatgccatga ctggtcaaga tgccgtcaac gtagctgata
    11701 gcttcaacca gcaattaggt attacagggg tcgtcatcac taaacttgat ggggatactc
    11761 gaggcggggc agcactatcg atccgctcag tgacaggcgc accaatcaaa ttcatcggtt
    11821 ctggtgaaaa attgactgac ttagaagtat tccacccaga tcgtatggct agccgtatcc
    11881 ttggtatggg ggatatgctg acattgattg aaaaagcgca gcaagactat gacgagaaaa
    11941 aagcggaaga acttgcacag aaaatgcggg aaaattcatt cgatttcaat gactttattg
    12001 aacagcttga tcaagtgatg ggtatgggcc cactggaaga tctaatcaaa atgatcccag
    12061 gaatgaatca agtccctgga atcgaaaacg tcaaggtaga tccaaaagat gttgaacgca
    12121 aaaaagcgat ggtttattct atgacgccag cagaaagagc aaatcctgat ctgttgaacc
    12181 caagccgtcg tcgccgaatt gctgccggtt ctggaaacag tgttgttgaa gtgaatcgaa
    12241 tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca aatgtccaaa ggggatatga
    12301 acatcccagg tatggaccaa atgtttggtt caggcgtcaa aggaaaacta ggcaaaatgg
    12361 cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa aaaacggaaa taagatgaaa
    12421 aaaacagctt cggtacagac tgaaaatgtc tactgccgga gcttttctat cagcaatttt
    12481 tattctttac taatacaatt actctaaacg aagaggtggc acagatgaga tgtccgtgga
    12541 gtgaacaaac agaaagtatg cggcaatatc atgatactgt ctggggtgtt cctgaatatg
    12601 atgaccaaaa gctgttccga aaattgatgc ttgatattaa tcaagccgga ttgagctggc
    12661 agacgatttt aaataaaagt gaagcattcg atgaagcata tgatcgattc gatattaaaa
    12721 aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat ggaaaacaaa ggaattattc
    12781 gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa agcagtcttg aaaattcaag
    12841 aagaaatcgg cagtttttca gagtatcttt ggtcgttttc taatggaaaa atcgttgatt
    12901 cttcttatca ttcacaagaa gaagtcccaa caacaagtcc tctttcagat gaattagcaa
    12961 aagatctaaa gaaaagagga tttaaattta tcggaagcac aacaatctat gcttttttag
    13021 aagctgtcgg gatcatcaat gatcaccttg acagttgttt ccgcaaagaa gaggtcgtac
    13081 gtatcggcag aaagggcgaa taaagcatgc gaaaatcata ttttatggtg ctataagttt
    13141 agatggctat ttggcaacga aaacggatga tcttcaatgg ctttttgaca ctccaacagg
    13201 taagcaaacc acttatgaag ctttttatga aacaatcgat acgaccatca tgggcagaaa
    13261 aacttatcag gaagcaaaaa aatatttgga gaccgaagca atttatccag agaaaaagaa
    13321 tttcgttttt tccacccacg cacaattaca attgccagat gctgaggtcg taaacgaaga
    13381 tcctgttgct tttctaaaaa atctacaaat gacagaagga aaagatatct gggttgtggg
    13441 tggcggtcga ttgatcaaac cgctattgga acatcaaatg attgatgaat ggtatatcca
    13501 gattacccct gtattattag gggacgggat tcctttattc caaaaaggaa catatgaagc
    13561 gcgttttgaa atgctagaca cgacacgatt cggtgaattt atcgaattgc attatgtacg
    13621 aaagtagaag taaataaaat aaaaaaggca actatatgca gaaatgtcct gtacatagtt
    13681 gcctttttta ttaccgttat gctttttact ctgttaattt gttagaaaaa tctagatacg
    13741 catctaaaat cgtttggaag aaacttaatg ttccttcaac gatattacca ttttcatcaa
    13801 ttagattcgc aacgtttccg atatatgctt ccggttgctg caaggttggc acattcaaaa
    13861 agacaagtga ttggcgtaga tggtggtttg cgccaaagcc gccgatccca cctggtgatg
    13921 cagtaacgac taaacctggt ttatgatccc aaacactgtg tccataaggt cttgagccta
    13981 catctaaagc atttttcaat actgctggca cagaacggtt gtattcagga gtaacgaaaa
    14041 cgacaccgtc tagtcccctc acttcctcac gaaaacgagt ccattcagca ggagcctgtt
    14101 ctggagtttc gagatcctca ttgtaaaatg gcagatcatc gatttttaca aatacacttt
    14161 cgtacccttc aggaagcaat ttcgcaaaag cttctgctac ttttttgttg taagaatctt
    14221 ttcttaaact accaataaaa aatccaattt tttttgtcat acgatttttc ctccttcaaa
    14281 ctatctataa taatcttaca aaagataagt aactggagca aataaaaaca cttactgaca
    14341 aaagctacat agaagataga ttacttattt ttaacaaaaa agaagtctaa aatcttctat
    14401 tttctaaaaa aaatcgaatt taatcaagct gtaaagaaaa aaagctttac agggtaaaaa
    14461 aaaactgtta cactacatct tgtgaataaa acaatggagg tggaaataaa taatggcagt
    14521 taaaatccgt ttaaaacgta tgggttctaa aaagagtccg ttttaccgta tcgtcgtagc
    14581 tgattcacgt tctcctcgtg atggacgttt catcgaaact gtaggtactt acaatccttt
    14641 gaaagaccct gcagaagtag ttttaaaaga agacttagtt cttgactggt tatcaaaagg
    14701 tgcacaacct tctgacactg tacgtaacat cctttcaaaa gaaggcgtta tgcaaaaaca
    14761 ccacgaagct aaattctcaa agaaataagg tgaccggata tgaaagattt aagcgactta
    14821 gtcttaacaa tcgttcgtcc gctagtcact tatcctgatc aagtcaagtt agacgtcgta
    14881 gagtcgaaag acttttacga gtacaatcta acagtggctc ctgaagatat tggccgtatc
    14941 attggaaaac aagggcgtgt tgctaaagca atccgcacaa tcgtttacgg tgttcggatc
    15001 aatgcaccga aaaaagtgcg tttgaatatc atcgatgata aggaaaagta aataaacgtg
    15061 ctgtactcga attttcgagt gcagcttttt tgtttttttt attaattgaa gaaatgatta
    15121 tttggcaaaa caagcaagaa agcgtatcct tataggagga gggagtgaac agccaatgag
    15181 aaagaaaatg ttatttattc catttgctct attgttaagc gcttgtagtt cggttactca
    15241 agaatcagac aatacacatc tatcaagcag tatatctgaa actgttacca gtccagaaaa
    15301 aagtagtacc aaaacggctt ccaccactga acaaacaatg gctacctcaa ataatgagaa
    15361 aaagactgct ttagaccagt tgaaagaaca acagccaaat gttcccatgc ctctagatgt
    15421 accagtctct tcaggctatc tcaatatcgc agcgacacat acaaagcaag gttattctat
    15481 tttatattac agaacagatc gtcccctcgg gttgaatgct gacgaattga atcaagaaac
    15541 gcctattgca acctatctat atcaatatgg gtttgcttct agtcaagaaa caatccaagt
    15601 tttgcagcca tttgagatcg acacaaatgg tcagcaagtg gacttaggtt ctcgaatcac
    15661 agggtatcag caaggtgcag caggttcaag ttttcttgaa tggcaagaag gaaactggcg
    15721 tattcgaatc cgtgggaata atatagaagg ccaagatccc ttactattag ctaaagaaat
    15781 cgtagcttat ttggaagaaa acagtctacc agcacctgaa caatttggta aaattactgt
    15841 tgatatgggt gatacgacga atcgagccgt agaagtaagc tggcaagaac cgaaaaatgc
    15901 ctatacgatc actcatcaag atcctatgtc tgcgttgaag atggcagttt ctatgaagag
    15961 gttgtgaaat cagcgcgctg atctgagccc atcatttaac tccaagtcac aggaagtaat
    16021 caaaaatagc acgccgcatt tttgcataat tttggcttaa taccttaaaa gaaaactaga
    16081 attgcctctt cacacatgct aaaataaaac agacaaaaaa gaaatgggga tataagttga
    16141 ctgaatactt gaatgtagga aaaatcgtaa acacacaagg tatcaaaggc gaagtccgtg
    16201 ttatctcaac aacggatttc ccagaagaac gttacaaaaa aggaacggtg ctaacactat
    16261 tccaagacgg aaaagcacct gtggaattaa cagtcaaaag tcatcgcaaa cataaaaatt
    16321 ttgacttatt gagttttgaa ggacatcctt ctatcaatga tgtggaaaaa tatcgggatg
    16381 gcatattaaa agtgtcaaaa gacaactctg tagatctagc tgaaaatgaa ttctattacc
    16441 atgagatcat cggtctgcat gtattagaag atggaactga gttaggtaaa gtaaaagaaa
    16501 tcttgtcacc aggtgccaat gatgtttggg tcgttcaacg tccgaaaaaa gctgatatat
    16561 tgcttccata tatcgcttct gtcgtcaaag aagtcgattt agaagctgga gtggtccgtg
    16621 tagaaattcc agaaggactg attgacgatg aagattgatg tattgacttt atttccaaga
    16681 atgtttgaag gtcctatggg ggaatccatc atcggtaagg ctgtagataa aggattatta
    16741 gatatcaata tctctaactt ccgcgattat tcagataaca aacatcagac agtagatgat
    16801 tatccatacg gcggtggagc aggtatgctg ctcaaagtcc agcccatcta tgataacatc
    16861 caagccattg aaaaagctgc accggatgtc aaaaaaagag taattcttct tgacccagct
    16921 ggtaaacgat tcgatcagaa aatggcagaa gaattttcac aagaagaaca cttagtattc
    16981 atttgtggtc attatgaggg atatgatgaa cgtatccgca cattagtgac agatgaagtt
    17041 tccttaggag attatgtcct tactggggga gaattaggtg cgatggtcat gatcgatgca
    17101 acagttcggc ttttgccaga tgtgttaggg aatcagactt cagctcaaac ggattcttat
    17161 tcaaccggtt tattggaaca tccccaatat actcgcccgg cagaatataa agggatgaaa
    17221 gtaccagaag tattgacaaa tggaaatcat aaattgattg aagaatggca attaaaagaa
    17281 tcactaagaa ggacctatca acgtcggcct gatcttttgg aaacacttga atggacacct
    17341 caaatgacga aatttttaga agaaatcaag aaagaagaac aagaaaaaac agcagatgaa
    17401 gccaagtgac tttttctaaa atcttcttta cagtaggttg ataatatgtt agtattttat
    17461 ggtgagtgca aaagcactta actattacga tattccgctg tgagaaaagc tcataagaat
    17521 atttggaata aggagaagaa aaccatgaat ccattaatcg aagaattaac aaaagaacaa
    17581 ttacgttctg acatcccagc gttccgccct ggtgacactg tgcgtgttca cgcaaaagtt
    17641 gttgaaggta ctcgtgaacg tatccagtta tttgaaggtg ttgttatcaa acgccgcggt
    17701 gctggaatca gcgaaactta tacagtacgt aaagtttcta acggagtggg cgttgaacgt
    17761 acattcccat tgcatacacc acgtgttgca aaaatcgaag tagttcgcta cggtaaagta
    17821 cgtcgtgcaa aattgtacta cctacgtgca ttacacggaa aagctgctcg tatcaaagaa
    17881 atccgtcgtt aatcattgtt atcagactga gaaagaaccc ttggtattca agggttcttt
    17941 tttcttagca tgtaatttga acaccctgat ccagtttttt ctttaattat tggtagggga
    18001 gaataatgga ttagaataaa tctacctata agtagtagta aaaaaaagag cactatgata
    18061 atatctttct taagagtaac cgctttaata aaaaatccag aatattctaa cataaatgga
    18121 gtattcttag aatcaaaagg agaaagaaga tggtttatac ttatacggag caagaaaaga
    18181 tgaaagtttt agacacattc atgaatgatg gaaaagtaaa acaagtacca agttcaacaa
    18241 aaaagaaata catcctattg aaagaagtct tgaaacgctt tgaccatgga gtgacttata
    18301 cagaaacaga ggttaattcg atactgctga acgtattttc tagtggcgat tatgtcgaac
    18361 aaagacgtta tctaatcaca tttggctttt tcaaaagaag ttcagacggt cgggcatatc
    18421 agatgatggg aattgaaaat tagaagtttt aatttatact cattgaaaaa agttcaagta
    18481 tgcgatattg gttctacacc gcatacttga actttttttg tcatctgtat ctataataca
    18541 aagccaagaa cgttattcaa aatatggata gctatgataa aagctaatga gcgattcgca
    18601 gttaaataag caatcgtcag taaaatcgtt ccaggagcgt acatgaaaaa atcaattgga
    18661 tgcgttacat gaataaagat aattctcttt tatttgtacg aataaatacc aaaacgtacc
    18721 tcctaaaatt agattttgga cagatgccct ttaaaaagat aacaagattt cgttcttgaa
    18781 acaatatata tgcttttatt ccaatgaggt tgtgaaaaca gtattttgtc ctgagcgtta
    18841 gaaaattgaa aatggggaat agcaactcgt actttaccat tttttaagtg aatacaagat
    18901 cagctaattg aacaccgttt attcgtgatg agggacacaa cactgcagtc gacacatttc
    18961 tcttttatgt tcaaagataa caaatattta aaacaaagaa aaatagtaga taatcccgtc
    19021 ctaactcttt tattcttccc tcatagcttc caaatttaag caatacttca attaatcaag
    19081 ttttatcttt ttttttcaat aatcgtaaaa aaagagtatt ttttatttaa aaataaaatc
    19141 tttgtattaa aggacaagac taaaataacc ttagaataaa aagagaaaaa aagccccaaa
    19201 ctttctatac atcaataaaa taataaaaat taaatttaga ataacgtgta aaggattatt
    19261 tgatgatttt ttattgagag gagggatgaa aatgattaag aaaactcaaa ataaaatcca
    19321 acgtatatgt caaaaacatt ttgtttctag actcaaagct gtatctaaaa gaaaatactt
    19381 acatcccatt atgatttcga tcatcttgat ttttactttc ttagggagct tatcaagtat
    19441 ttatgtaaac gtttatacag aaacgtcaaa ttttgctaac caaacgacag aggagacaaa
    19501 tagtccaccc tattctgaaa tacagtccat agaaagcacc aatcagtcta gcaacaacga
    19561 gacaacctca accacatcct cgactcaact gattgatccg acagaaaaag aaatcacagc
    19621 agcaaaagca gcaggggaga aagcttattc agaaacaggt agaagccaga catttagtac
    19681 tgttgcggcc actgcgaatt tcaacggaca taccatacca gatggatata cagtgatata
    19741 tgccaaagat ggagtcattg ttgcggttaa cggatcgatg agtgcggata aaactgcgtt
    19801 acaaggcgta accaaagcaa tcgcttttat tgataaccgt ccagatatcc ataatctgtt
    19861 tattggctcc acagtaaatg gtactactat cacattccca aaaagtatct atatgggggt
    19921 ggctaccgct ggaaatacga tcgattcagt tacacccaat gcggataaaa gttattcttt
    19981 tacaccctca acatggggag ggcttcctgc cggaggaggt atgagtactt tttcaatcgg
    20041 tatacagtta gcaaatgata ttccattcac ggggtactcg atcaaaaatg ggcagatcgt
    20101 tgatggtaag ggaaatgttt caaattttcc aacctatcaa gcagcaacgg ttcaggtcaa
    20161 tgcgaatcgg acaggaactt tttcttatac agtcaatggt ggagcagcaa aaatcggaac
    20221 gtacgggact acattatctg gaatccatgt gggtgacaaa gtggttatca ctccaacagc
    20281 agtaacgggc tattcttttg cacaaacaaa cggttctttc acagccctag aaagtaacgt
    20341 cgatacggtg acctatacag gcaaacaaac accaatcact attaagtatc aagactattt
    20401 tggacagatg attgctcctt ctaaaataat gaatcttact tacggaagtg ctgcacaaga
    20461 cctgacgact aatacgccta ctatcaacgg atataccttt acagctgttt cagcgacaga
    20521 aacaaagaac caatcagcaa tgagtgtttt agctagttta gatacaaatg gaaatgtaat
    20581 cgtaaaggac gcaaatggaa aacagatttc tgaagtcatc ctatattata agacaaatgc
    20641 aacagtatca atcaatgcaa atggcagtaa gtactatgat ggtctttctg ttgtaccgat
    20701 cgttaaatat gcctttaatg ataaaacaga atcaacatcc cttttaaaca atgatctcag
    20761 tattgatcaa atcacatgga atccaactga tttcaaagcg atgaatgaaa agggagttga
    20821 agtaactgcg cctactgaaa ttggaaccta tacgtcttgg caattgacaa aaagcggact
    20881 agctaaacta gctgccagaa caaactattt atttactatc gtgcagacat ctgatgtcta
    20941 tacgattaag caaatcagcg gtgcggtaga gctcagtggc agtaagacat atgatggaaa
    21001 agcaggtgtc ccgtcaatcc atgtcaagct agcagagggt gtcactagtt cgcttactcc
    21061 agtacaagtg gcacttagca gtatggatta cacagcagat gcacaatcag caaaaaatat
    21121 ggttaatgct ggcagctata caattaaact aacgaatagc ggaatagaca aagtcaaagc
    21181 agcaaatccc aagttgtcat ttactgatat agccaacaca tcaggaactt ataccatcta
    21241 taaagctaac gcagtgatta ctgtcgatga cgctgccttt aattatgatg cccaaagtca
    21301 ctcgatttcg gttggaaatc tccacgttac cggtgttgtc ttaggcgaat cattggatta
    21361 taccctaaca gttaacagcc ggacagatat tggatcacaa atagtaacga ttagtttagg
    21421 cgaaggaagt gtaaacaata attatacgat tatcgcaaca gataccgcta agttgacgat
    21481 caatccgact ctcttgcttc cttcgacagg tgggataggt ctactgccct ttgtcttttt
    21541 aggactgatc tttatttttt ctggcttctt ttattttatc catcgtaaga aaaaagcagg
    21601 tgaacagcga tgaaaaaaac aaaaaatgta cgtgtggata tatttgctgt tctctttttt
    21661 atcctactgg tcttttttat aggttctccg actgtgtcag ctagagaatc acctattaca
    21721 tttactttgc ataatcgaat gttcgaaagc gataagatgc caagtatcag tcaaaacgac
    21781 ggaataaata tcccggataa ctttcaagga gtaaaagggt tgaacggcgt tactttcgct
    21841 atatatgatg tctcggatga attttacaag ctgcggtcag aaggaagtag tgtggaagac
    21901 gcacaaagaa aactagcaca aaaaagtgat agtgaaaaaa tactggcaga aaatgtgaca
    21961 aaaacagtag acgaggaaga gggcattgct tcttttagtg catcggacaa agatgagcaa
    22021 ggtcgtgacg ctgtttaccg atttgcggaa ataaagactt cagattaagt aaaagaaaaa
    22081 tcagcaccat ttgtcgttgt gcttcctgtg acagattcat ctaatcataa attgacgacc
    22141 atccacttgt atccaaagag cgaacaaaaa atacctgctg cactcacatt aacaaaaaca
    22201 gtagagaata agcagacaga ttttgcagat ggggataaag ttccttatct catcaccgta
    22261 acaattcctg agaacatcaa cgagatagga acctatacga tcaaagatac agctgatcct
    22321 cagttatggc tagaaccaga aacgatcgat tttttgattg gtggagacaa gattcataca
    22381 tttcacacac aaaaaacaaa acatggtttt gtcttatcag attctggaaa agatcttagt
    22441 tcgtttgctg ggaaaaaatt aacgatccgt taccaaatga cattgaaaga aaacagtgaa
    22501 aaaacgacat ttgataacga tgtacgtttg acgactgaca atcaaacagt agaaacacat
    22561 cttgccatcc aaacaggagg caaacaattt gtcaaagtgg atcggcaaac gaaacaaaaa
    22621 ctagcagatg ctcaatttct agtcaaaaaa aatgaccaat acttagcgca agaaaacggg
    22681 ataaatcatt gggtagccaa agatgattca agagcaacga tttttacttc cagtaaagat
    22741 ggaacatttt ctgtccatgg attgtctttt ggaagttacg aactagtgga gattaaaccg
    22801 cctaaaggat atatattgag tcaatcaacc attctctttg aagttgaaaa aggcagttat
    22861 gatccgcttc atcctatacc attggaaatc atcaacgaac caaaagcaaa tccgacgaat
    22921 aatggaaaaa cgccagttca gatgcagaca aatggtccat caaatgaaaa aaatggagga
    22981 agctttccaa aaacaagcga agagatgctt ggaggtttct caattttagg gttgttgcta
    23041 gtcctttcaa cagggacagc ttggttttat aaaaaacaac aaaaaggaaa caataggagg
    23101 gaaataaaat gaaaaacatc aaaacaaaaa tatggacgtt tttaggaact gctatcatgc
    23161 tgcttccttt cgttctcggc ctaggaactg cagaggtttc taggccgtat cacctacacc
    23221 agaaaatgtt acggttaatt tgcataaatt gaaattcact tcagcaccag aaaatcaaat
    23281 aaacaacgga acggaattga catttccgaa tagcgaaccg ttgaacggcg ttgaattcaa
    23341 cgtatatgac atcactgcta cgtactatcc aagtaaagac acagcagttc cagcagacgc
    23401 tacacccttc gcaagtgtaa cgacttctgg tgaaggatta gctaacctga ctcttccagg
    23461 taaatctgat gggaaagatg ctgtatacgt ctttgtagaa acaccaaagc ccggtgtcga
    23521 aacgtcgcca aatatcgtgt taagcttacc cttttataac ccgaattcat cagaccctga
    23581 caaaccttta gacacgattc acctatatgc taaaaatgtc atcaaagaaa gcaatatcaa
    23641 aatccagaaa gctgggaact tttcaggggt agataagtta gcaggggcgc aattccagat
    23701 caaaaattca gagaatcaat tcgtgaccgg ttttgatgaa aacactggtg tcgctctcta
    23761 tgatcctgct gagtcagcgt tgacattcac aactgatact gaaggatcca tcagtgtcaa
    23821 tggattaata gacggcaatt atactttagt tgaaacaaaa gcaccagatg gttatcaatt
    23881 aaccaatcca caaaaagaaa ctacttttat agtaaaaaac ggaaaattgc aacaaacaac
    23941 cggtatcatc catggcgcag atgaagccaa tcttgggaat ccaaacggtg tagtcaatcg
    24001 ggaaaataca actacggata acacgattac tgtagaaaat gtccaaaact acggtgattt
    24061 ccacttcatc aaacaagatg tgaacacgca agaaaaatta gccgatgcag aattttctat
    24121 tctaagagca aaagatccaa ctgttaaatt aatgaaaaaa atagcaaatc ttgcctcagg
    24181 agaataccca tatgcttggt cagatgaagt cacaggttct gactgggaag aagtgaaatt
    24241 gatttctgat tcagaaggga aattttcaat cgaagggctg aaacaagggg catactgcct
    24301 tcaagaaaca aaagcaccag aaggctacgc attacctaag aatgaagctg cgtacactga
    24361 atttacagta gatgatgatc caacaacttc tgatgaaaca acgatcgata accaacctaa
    24421 aggaatcttg ccttcaactg gtggtatggg gatcatcgta ttcatcttgg taggtactgc
    24481 tttagttgga ggagcagtga tctacttcaa aaaacgccat caagaaacag aagcttaaac
    24541 tattggaaac aaaaatcata cgataaataa acgatagtga ttcaaatggg gagaaaggtt
    24601 gtgacaagtg gtcggtctct tggtattcgc tcaacaaacg gcaaaatagg aggaactatt
    24661 ttgccgtttg ttgagcgaat actcaggtca aggcgctgat ttcacaacct cttcatatac
    24721 atattagaaa ataggtggac atgatgaata aaagcagaat aagaatactg gacatcttca
    24781 tggcaatcat tttagtcgtt gggatcggga tcttttctta tccttttgta gaagattcac
    24841 tgaatgattt tcttgcccag caaatgatca tccattatca aaagcaagca tcgaataaga
    24901 attcagagga aataaaaaaa cagcaggaaa aaatgacaaa gaaaaaccaa cagttggcag
    24961 agcaaaacgt atcaccaggg ataggcagtt tcaaccaagc agttgatgca aaagcattaa
    25021 aagatttacc tagtaatgcc ttttttatgg aacatatgct tggagtcatc gaaatcccaa
    25081 aaatcaatgt cagcttacct atattcgatc agacaacgga aatatttttg caaaaaggaa
    25141 cgtcattatt ggaagaaagt tcttatccga ctggcgggaa aaacacccat gccgttcttt
    25201 ctgggcatcg tggactccca gaagcaaaat tatttacaga tttgcctaag ttgaaaaaag
    25261 gagaccagtt tttcatccag atcaatggaa agacattggc gtatcaagta gaaaaaatcc
    25321 aagtggtctt acctgatgaa gtagattctt tgggtatcca aaaaggcaga gatctcgtga
    25381 ctttgcttac ctgtactcct tatatggtca atacacatcg actgcttgtg acggggcatc
    25441 gtattcctta tcaagcaaaa gaggcaaaaa aagcgatcca aggaattgat caatggaaaa
    25501 aatggaaatt ttttatttgg tttatcggta tactacttgg atcaatcggc ttagtttggc
    25561 tactcatcgc ttatttagat tctttggcca tcgctaagcg aaactatcct ttatcttttt
    25621 atgtaaagaa cacaaacgga cgaccaatcg aaggaatggt cttttctgta aaaacgctca
    25681 acggcaaaca ctatattact agagaaaaag ttccatttgt gaaagcttct gatgaatacg
    25741 gactagtgag attttctgat ttaaaaggca ggaactatcg cttgcaacat gaggagctcc
    25801 tgcttaaaat ccatgtaaaa cataaacatt cgaaacagtt ttcaatgaaa ttgaaaaaag
    25861 gaagatataa actgcgaaaa gaaaaagagg tgtactattt gattgagaaa gaatgaatga
    25921 agatgtccaa aaaagcagag ggaacagact aaatgaaaaa agagagaagc tgacgaaatg
    25981 gacgtgtaaa ctgctatttt tggtttacta tctggaacgc cagcttctat ttttttatgt
    26041 ttcagaagaa ttttattatt atagtataac ttttgaatta gtttccataa catttggagc
    26101 aaggggttaa accacgagct tgagcttcgc ttaaagtggc aggggtatac gtaccatttc
    26161 cacatttatg tgtatggtat tttgaaccgg tcggtgtgac atagacagtt tgttcattat
    26221 tttgctcagg agctgcggct tgtgcctgct gagaggcctg ttcagctgct gcttgctgtc
    26281 gcgcctgttc tgcttgttgc tgtgcgattg cttcttgttg cgcttgttct gcttgttgtc
    26341 gtgcaatttc ttcttgcttt ttccgttctt cttctgcttc ttttgctttg attgtggaat
    26401 caattgcagc aagacggctt gtcaactctt gtttgttttc aggtagcgct tggatagctg
    26461 ctgaagcagt tgcatagttt tcttttgtag gatttgcttc agcttgtgac aaagcagatt
    26521 ccgcttctgt cacttttttt tctagtgcag ctttttccgc tttttgtttc tcttcttctt
    26581 ttttcttttc aatttgttct tgttctttcg atgaatctgc cgtactttcg gagatcgtgg
    26641 tactgctgct ggaagcctga gctgaacttg tgctttgagt agtagacgta gtagcaccac
    26701 acccactcaa caaacttcct gcgaccaaaa acaatgcaac taattttttc actaaatttc
    26761 ctccttaagt aaaaaacaac cgttttcaat aaatgtcctt ttcaattgtt tacttacttg
    26821 ttataataat tgtgttatga atagtgattg aggaaactta atctaatccc gttttgatac
    26881 acgggatttt ttgctatagt tctgttatta agtatgcaat aataaaatat gtacgttatt
    26941 ttattattag attattgaca tttatataat aaacgattaa atgattcata tcaatagaat
    27001 acttaggaaa aaaagagaaa taataacagg tttatgcact attgacggtg tgacaatatg
    27061 atatttgtat ccgttttttt tcttgtatgt agtatagtaa agtagataca ggaggagaaa
    27121 atatgcagac ttttttaaca aaagtttctc aaaagaaaat taaaatgatt catttactgc
    27181 ttgaaacaga acgttggtgt tcaatagaag aactacaaaa cgaattgaag gtatcaagta
    27241 agtctatctt gaattatcta acagatttag aagaattgtt ccaaaaatat cctgataagg
    27301 tcattttgaa gaatgagaat aatcggcgct tttctatgga aaagcaggag aacttcccaa
    27361 tctacattat ttatcttcat ttctacagaa aatcatataa ttatcatttg attgaattca
    27421 tgtatcaaca tcctgagaaa aatttggaag attatgcaga cgctcaatat acgagtgtat
    27481 ccacagtttt tcgttatgct aagttattag taaagtactt tgaaatgacg gacgtcaaag
    27541 aatagtagcc gccagataga aggaaattag cagttgaaaa agctgccctg catcaagtaa
    27601 tacgaccagc caaacggaaa cagtgtctca tgtttttgat ttggctggtc ttattaccgc
    27661 agatgcaagc ttttgccaca cctctttctt gtcatttaca gactcaacta tcaatgctgc
    27721 aagctttccc ttaatgctgt aacaccagta agagttgtca agaccagcag actgactagg
    27781 taaataccgc tcaaaaacaa gattacggca gttaaactat aatgatccat caagaaaccg
    27841 atgacgatag aagaaaaacc accaacagct cgtccaaggt tcataatgaa attattcgcc
    27901 gtcgcgcgga tttctgttgg atacaaacta ctaatcactg cgccatatcc accatacatg
    27961 ccattgataa agtagccgac tatcacagcg gctgctacca aactccactg gctatgggct
    28021 aacacaagta gatagacaga taaggatgaa caaattaaaa acaaagaaaa ggctagttta
    28081 ggccccaatt tatccatgat tatgccaaaa gtcatcatcc ccaaagacat gcctaaaata
    28141 gtactgacca tccacaatga agacccagaa accgaaagcc ctaatcgatt ttgcataatt
    28201 gaaggcagcc aattcattaa cccaaaatag ccggcaattt ggacagttac catgatacta
    28261 aggccacatg tttgccaagc aagatgtttt gattcaaaca gtctgctaag tttggttttc
    28321 ttttcggcag attgtacaga tttgaattcc tttggttcag tcaagccgcg acgaatgaac
    28381 aagaccatca acaccggcag tacacctacg acatacaaca tcttccaacc aaacgttgga
    28441 atgatcacag cagctaaaat cgcagccaaa gccgcaccga cctgcgcacc aataccagca
    28501 accgaagaag ctcgtccaat ttgttttttt gaaaaacttt cggaaatcaa ggacatacac
    28561 gccccgtatt ctcctcccgc tcctacacct gcgataaagc gaaagagata aaccaagtag
    28621 atgtttgaag caaaatacat caataaagaa gcaatcgaaa acagaaggac cgtttgagaa
    28681 aatactttca cacgtccata tttatcagct atgatgccaa aaaaaatacc tccaatgagc
    28741 atccccaaat tagtgatcgt tgaaatgaaa cccgcttgcg taccactaat atgaaaagaa
    28801 gtaatcattg aagataatga aaaagctaaa aacataatat ccatattctc taaagcaatt
    28861 cccgccgatg tcgataataa taactttcgc tgatacgttg tcatttttat accccttttc
    28921 ctaaaatttc cctaaattgt taaaagtata tccaaaaaag aataaaaaaa caagactttt
    28981 ttatttgaaa taatacacaa acaaccgata tagataatcc agcttagttt taatagaaat
    29041 gagtattgac ttggagtaca cttaaagttg tagaataaat aaaatacata agtaaagtgg
    29101 caagaaatta agagaaagag tgatcagatg aatatcaaac aagtcagtga agaaaagggc
    29161 atttcggccg atacattgcg ctattatgaa cgaatcgggt tgattccacc agttaatcgg
    29221 acaaaaggcg gaatccgtga ttatacagaa gaagacctaa aatgggtcga ctttacgatc
    29281 tgtatgcgaa atgccggatt atcgatcgag tctttgattg aatatattcg cctatctagc
    29341 gaaggagaag caactgtatt tgagcggcgt aagcttttga ttgaagaaag tgaacttttg
    29401 acgaaaaaaa ttgctgaaat gcaagaatgt ttggaacgtt tacaaggaaa aatcaagaaa
    29461 tatgatcgtg tgttatctag aaataaaatg gaatgtatca agtaaaaaaa tcaaggagca
    29521 tcgctatgga gttacgctta ctaaaatatt tttggacaat tgcagaagaa ggaacaatct
    29581 ctcaagccgc agaagttcta catcttacac aaccaacctt aagccgacaa ctgaaggagt
    29641 tagaagagga actaggaaca gaactgtttg tacgcgaaaa ccgcaaaatg atcttgacag
    29701 aagcaggtta ttttctaaaa aagccgagca gaagaaattt tagatttaac gaatcaaacc
    29761 actcaagaat tcgagaacag aaaaaaacaa ttattcagcg gccgatttac gatcggctgt
    29821 gtggaagctg ataattcgaa tacattggca ctattactag aaaagttgat ccgtgattat
    29881 cccagcgttc aatttcatat ccacagcgga acaagtgatg atatcacgga gtgactagaa
    29941 aaaagcctgt tagatttagc gattttgcta gatccagtag atacagagaa atacgaaacg
    30001 attttgttac caagaaagga aaaatgggga ttgctcattt tagaaaattc tgttttagca
    30061 aaaaaagacg tgataacaaa agaagacttt gcgaatgtac ctcttttgat ctcaaagcgt
    30121 ccagaaatac agcgaatgtt tgctgactgg ttaggcataa aaaaggagca gttgctgatc
    30181 acaggaacgt acaatttgat tttcaatgta tttgcgctaa ttgagaatca ggtaggtgct
    30241 gctttagtca tagaaggtgc tgtaagtcat ctttcaaagc gagtgacatt cgttccgctt
    30301 gacccaatga ttgaaacgaa ctgcatgcta gtctggaaaa agaatcggat tttatcacct
    30361 gtagtcaatg aattgattca ccgtttcaaa gaagcttttg aacagtaata agtatctcta
    30421 atcgaagaaa tttcaataca aaagcgagac gtatgacagt cttgcttttg tattttttca
    30481 tttttaaatc aaaaaaaata aagagattta cataacttgt taaataagcg cttacaaaca
    30541 taagaagaac ggaaatgaat cagctataat aaccgttgtt ctggattgta atcattacaa
    30601 acaaatgaag attataactt tggaggtgtt cgaaatgaaa gaaaaaaagc aaaaattcgt
    30661 tcaaaaaaca tgccctttat tcaatggttg ggtatgattc tgctgattgt attagcttta
    30721 ttgacgatca ttcctttttt atggatggtt tctgcttcat tcaaagcaaa taatgaagtg
    30781 ttcacgattc cgattcaatg gatccctaaa acttggcatt tagagaatta tctggttatt
    30841 tggtctcgta ttcctttagt gacatttttt aagaatacag cttttttaag cgttgtgatc
    30901 acgttgattc agttgtttac ttctagtttt gctgcttacg ggttttctaa actaaatttt
    30961 aaagggcgcg atattttatt tttagcatat atcggcacga ttgctgtccc ttggcagtct
    31021 tatatgatcc cgcagttcat tatgatgaga aaagtgggtt taacatatac gttgtggtcg
    31081 ttggtgctat tacaagcgtt caatgctttt ggtgtgttct tgttgaagca atactacagt
    31141 agtatcccag attctttatg tgagagtgcg cggatcgatg gcttatcaga gtggggaatc
    31201 tatcgcaaga tcattttacc tcttacaaaa ccggcgattg ccagtttgac gatcatcaca
    31261 ttcgttaata catggaacga ttatatgggg ccattcattt atttgtcttc tacggaaaat
    31321 aaaacaatcc agttagggtt gaaaatgttt attgggctat ttgatgcaga gtacgcatta
    31381 atcatggctg cctcagttgt ttctgttctt cctgttgctt ttatattttt agcgatgcaa
    31441 aaatattttg tagaagggat cgcttcatca ggaatgaagg aataggaggt gattatgaaa
    31501 gagcagcgtt ttgacaaaaa tgtttatatg gaattctttt attggttgta tcaatcattg
    31561 gcaagtagcc tttgtttttg gtgtgtcaat atcttgtata tagcagctgc gttccttttg
    31621 tcgatagatg gaaggaatgt cttttccttt attttttctt tactttttat tggtccaggt
    31681 tgcatcgtga tgataggtat gacagaagaa ttagcaaaag aaaaaagttt ttcaccagta
    31741 cgtttgttca taaagacgtt tcgccaattt tggctaaagg gattttttta ttggctattt
    31801 gcttggatag ttagtgtgat aatgattttt gattgtttct tttttatacg tttttcttat
    31861 ggaaaatggt tgattccgtt gtttgtttta cttgcttgtt tatcagtttc ctttagcatc
    31921 aactactggt attttcaggt gagaaatcca gcgtcgaaac caaatcaagt tctacggata
    31981 gcgttctact atacgttgaa aaaatggtat gtgagtttac tagatttttt actattgaca
    32041 agtttgtttc tcttcttttt cgtaaagccc caatggtgta ttctactagg tccttctatc
    32101 gtatttggtt tgatttactt caacaatcgt aaattgatga gaactatgga tctgtagact
    32161 ttataaattg aaactttcaa ttaagaatga cagtttttat gtaaaaactg tcattctttt
    32221 tcattttttg aaacatatgg ctaaacaaat gaaataaaac gtgctatact tttgaatgaa
    32281 acaggtttag aaactgtatc aattatttgt gattatttct aactaataat taaaaataaa
    32341 gcataaaaag gacgatgttc aatggacgaa aaaatgaaac aaggttcgaa atctgtagta
    32401 gaaagtttga ttaatcatca tgttgattat gtattcggta taccaggtgc aaaaatcgat
    32461 ggtgtattta atgaattaga ggatcaaggt cctgaattaa tcgtgactcg tcacgaacaa
    32521 aatgctgcat ttatggcaca agcaatcgga cgtattacag gagagccagg agtagttatc
    32581 gcaacaagtg gtcctggtgc tagtaactta gctacaggtt tggtaacagc gacagcagaa
    32641 ggtgacccag ttttagcaat tgccggacaa gtaaaacgaa gcgatctatt gaagttgacc
    32701 catcaaagca tggataatgc agcactgttc cagccaatca caaaatacag tgcagaaatc
    32761 caagatccag aaacaatttc agaagtgatt gccaatgctt atcgtatggc taagagttca
    32821 aaaaaaggcg cgagctttat cagtatcccg caagatgtag tggatgcacc tgtccaaggg
    32881 aatgtcatca agccattgag cgatcctaaa ttaggttctg cttctgcaga tgatatccgt
    32941 tacctagctg aacgcattag agaagcaaaa ctaccggtac tattagtagg tatgcgagga
    33001 tcaagtgaaa aagaaacgtt agccatcagg caattagttg gaaagacagc attgcctgtt
    33061 gtagagacat tccaagcagc tggagtgatc tcacgtgaat tagaagcgca tttctttggt
    33121 cgtgtgggtt tatttagaaa ccaaccagga gatatgcttt tgaaacgaag tgatctagtt
    33181 attgctattg gctatgatcc aatcgaatat gaagcaagaa actggaatgc ggaaaaagat
    33241 gcgcggatca ttgtgatcga tgaagcgcca gctgaaatcg atccttttat gcagcctgaa
    33301 agagaattga tcggtgatat ctcagccact cttgatttat tgacaggttc attagagcct
    33361 caacaagtgt cagaagatgc aaaagaatat ttagcatctc ttcaagcaga attaacggag
    33421 cgggacattg ttcaatcaaa aggagaagca ggtatcttgc atcctttaga agttattaac
    33481 acgcttcagt caaaagtaac agatgatatg actgttaccg tagatgtagg tagtcattat
    33541 atttggatgg cacgccactt tagaagttat gaacctcgtc atttgttatt cagtaatggt
    33601 atgcaaacgc ttggtgttgc attgccatgg gcgatttctg ctgcattggt gcgtccaaat
    33661 acacaaatcg tatcagtttc cggcgatggg ggatttttat tctctgccca ggatttagaa
    33721 acggcggtac gtaaaaaatt gaatatcgtt catttgattt ggaatgatgg acactacaat
    33781 atggtagagt tccaagaaaa aatgaaatat cagcgggcgt caggtgtaga ctttggtcca
    33841 gttgattttg tgaaatatgc agaagctttt ggcgctaaag gaatccgagc tacaagtgta
    33901 gaggaattag aaaaagcttt agaagaagga tttgcgacag aaggacccgt aattattgat
    33961 attccgattg attaccgtga taatgagaaa ttgggagaaa caatcttacc agatcaattc
    34021 tattaaggaa gtgtcgacat gactgaaaaa atcttatacc agcacgggac attaggagct
    34081 ttgatggctg gcttgatgga tggaacagaa acgattgctc atatattaga aaaaggaact
    34141 ctgggattgg gaacattgca tgggcttgat ggtgaagtca tctttttaga tggcgtagct
    34201 tatcaaggaa gatcagatgg ctcagttgcc caattagatg gaagtgaact taccccctat
    34261 gcagcaatta cagattttac gccagatact agtttttctg tctcaaaaac tgcagatgga
    34321 gaacaattga aaaaagacat attagtaaga gaagccgggg aaaacctatt tttggcagtg
    34381 aagataactg gattattcaa aaatatgcac atccgtatca tgccgaagca agaaaaacct
    34441 tacagaagac tagcaaaaat ttcagagtct caaccagaat tccaacaaag caatgtccaa
    34501 ggaacattag tcgggttctt tacgcctgaa ttattccaag gagttgctgc agcgggattt
    34561 cacttgcatt ttatcgatga tacacataca tttggcggac atgtaatgga ttttgaagtg
    34621 gctgaaggaa aagttgagat tagccgcatc tcgtcccttg tacagcattt tccagttgat
    34681 gatccgactt ttgttcacga aacgattgat tatgctgatt tagcagcaga aatccaacaa
    34741 gcagaataga aaaagacagc gagatgcgtt caaggtgatt aacctgacgt atctcgtttt
    34801 tttgaggagg aaacctagcg tttacaaaaa aactgagcta taatcttctc catagatcaa
    34861 aaaggagcgg tttttatcat gtggacagaa aaacagaaaa aagatgcata cgaaatttta
    34921 ttattacagc aacaaggatt attagaagca gaagataact ggttagcaaa tttagcaaat
    34981 tcatctgcat tgttgaatga gactttgcct gagactgtct ttgcaggata ttatttattc
    35041 gatggtaatg aattgatttt aggaccgttc caagggcgag tttcttgcac acgtatcaag
    35101 atgggaaaag gagtttgtgg agaatcagct gaaaaacaag aaacattgat cgttgatgat
    35161 gtcaaaaccc atgcaaatta catttcctgc gattcagccg cacaatcaga aatcgtagtg
    35221 ccaatggtaa aagaaggtaa tttaatcggt gttttagata tcgattgcgg agtaacgaaa
    35281 gggtatgatg aaatcgatca agcatttcta gaaaaatatg tagatctttt attagcaaat
    35341 tttaatataa atgctttttc atttattaat aactaaaatc gtctattgaa acaaaaaaga
    35401 agagaaatca agaataaaaa gagccggaaa gacagtgggc atttctgttt ttcggttttt
    35461 ttattttttt ataaaatcac aagtgttatt gattttcata atcatatttt aatggtatta
    35521 tcattttaaa taatggaaaa acattaagga tggatgaaat atgaataacg aaactatcat
    35581 tttaggaaaa aaatatattt gccaacctat tggcttgaaa caaaaagtgg ttggagaagt
    35641 aatcagtaaa ttagaaaatt gtgttgtgat ctgcgtagac gaatatcatg acgtcgatcg
    35701 caatgaaata ttagaaaaat gcggaaaagt agtggcaaaa tatactcacg tttatgagtt
    35761 ggaaacaaca gaatatctat ataactatag caacaaatat gaacatactt tagtttcata
    35821 aagatttaaa taaagtgcct tcaaaagcga gaagaccaag cttttgaagg cactttattt
    35881 agttggcagt gattgttcat gatttttgat ttattcaaaa ggttcgccta gagaatctgt
    35941 ctctgtaacg aggcctggtg gagaaactcg ataaaaacct atactgccag aactgtccta
    36001 ttttcggata gacaaactag tagttttaaa aagatcatcc gatccaatca tttcaaaaaa
    36061 tgcaaaactg atatcaggat catttagctc aggcttgtta tcgtaaagca tttgtaaagg
    36121 ttgcatttag ttaggagtaa acgcgaaact atcatcatta tttgctgaag aagatgaaga
    36181 agctaattca gagtttgttt gaaataaagg agacgtgctg acagtttctt taccctgttt
    36241 tttgcagagg tagaaacttt tatatcggaa gtttctaccg gagaattttt ctcatttgta
    36301 gaaattgttg aatcgatact attcgaaatt tgcgtatctg aaggtatgtt ctttgatgca
    36361 gaagtcccac aagcagtaag taacaataaa tttgataaac tgataaacag aattcttttc
    36421 attatgtaca cactccttat agtatcgttt agcatacacc tatgctcagt attaggcaaa
    36481 atcaatgcaa aactatcaag tcttttatag tatctattag tcttagtaat acatatatgg
    36541 agagggtgat atcccagttc aaaccagata cattggttac catctgtatt aacgattatg
    36601 cctctaaacg ctttttttat gaaaaaattt ataagtgaaa acgtaggtat gatattatct
    36661 agaggtaatt tttttgggta tttaaatagt tgctaggagg ata
//
LOCUS       DAIGUC010000025        36567 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.025, whole genome shotgun sequence.
ACCESSION   DAIGUC010000025 DAIGUC010000000
VERSION     DAIGUC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.025"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(25..1521)
                     /gene="lysS"
                     /locus_tag="NOB46_001348"
     CDS             complement(25..1521)
                     /gene="lysS"
                     /locus_tag="NOB46_001348"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCI1058290.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="NOB46_001349"
     CDS             complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="NOB46_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCI1058291.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="NOB46_001350"
     CDS             complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="NOB46_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCI1058292.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="NOB46_001351"
     CDS             complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="NOB46_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCI1058293.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="NOB46_001352"
     CDS             complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="NOB46_001352"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCI1058294.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="NOB46_001353"
     CDS             complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="NOB46_001353"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCI1058295.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8052..8522)
                     /locus_tag="NOB46_001354"
     CDS             complement(8052..8522)
                     /locus_tag="NOB46_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HCI1058296.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8568..8993)
                     /locus_tag="NOB46_001355"
     CDS             complement(8568..8993)
                     /locus_tag="NOB46_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCI1058297.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9060..9329)
                     /locus_tag="NOB46_001356"
     CDS             complement(9060..9329)
                     /locus_tag="NOB46_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCI1058298.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9340..10935)
                     /locus_tag="NOB46_001357"
     CDS             complement(9340..10935)
                     /locus_tag="NOB46_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI1058299.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="NOB46_001358"
     CDS             complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="NOB46_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCI1058300.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14488..15048)
                     /locus_tag="NOB46_001359"
     CDS             complement(14488..15048)
                     /locus_tag="NOB46_001359"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCI1058301.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKAVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15401..16375
                     /locus_tag="NOB46_001360"
     CDS             15401..16375
                     /locus_tag="NOB46_001360"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI1058302.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16545..17945
                     /locus_tag="NOB46_001361"
     CDS             16545..17945
                     /locus_tag="NOB46_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCI1058303.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18023..18745)
                     /locus_tag="NOB46_001362"
     CDS             complement(18023..18745)
                     /locus_tag="NOB46_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1058304.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18824..19330)
                     /locus_tag="NOB46_001363"
     CDS             complement(18824..19330)
                     /locus_tag="NOB46_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI1058305.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19453..21252
                     /locus_tag="NOB46_001364"
     CDS             19453..21252
                     /locus_tag="NOB46_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCI1058306.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21320..22894)
                     /locus_tag="NOB46_001365"
     CDS             complement(21320..22894)
                     /locus_tag="NOB46_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI1058307.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="NOB46_001366"
     CDS             complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="NOB46_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCI1058308.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="NOB46_001367"
     CDS             complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="NOB46_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCI1058309.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24671..25309)
                     /locus_tag="NOB46_001368"
     CDS             complement(24671..25309)
                     /locus_tag="NOB46_001368"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCI1058310.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25310..25960)
                     /locus_tag="NOB46_001369"
     CDS             complement(25310..25960)
                     /locus_tag="NOB46_001369"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCI1058311.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="NOB46_001370"
     CDS             complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="NOB46_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCI1058312.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="NOB46_001371"
     CDS             complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="NOB46_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCI1058313.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSREESSSSTSSSA
                     STSESSK"
     gene            complement(29103..29843)
                     /locus_tag="NOB46_001372"
     CDS             complement(29103..29843)
                     /locus_tag="NOB46_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCI1058314.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="NOB46_001373"
     CDS             complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="NOB46_001373"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCI1058315.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31214..32152)
                     /locus_tag="NOB46_001374"
     CDS             complement(31214..32152)
                     /locus_tag="NOB46_001374"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCI1058316.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32145..32636)
                     /gene="def"
                     /locus_tag="NOB46_001375"
     CDS             complement(32145..32636)
                     /gene="def"
                     /locus_tag="NOB46_001375"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI1058317.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32651..35059)
                     /gene="priA"
                     /locus_tag="NOB46_001376"
     CDS             complement(32651..35059)
                     /gene="priA"
                     /locus_tag="NOB46_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCI1058318.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35312..35617)
                     /locus_tag="NOB46_001377"
     CDS             complement(35312..35617)
                     /locus_tag="NOB46_001377"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI1058319.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="NOB46_001378"
     CDS             complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="NOB46_001378"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCI1058320.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9885 a         7990 c         6705 g        11987 t
ORIGIN      
        1 attccttaga cagcttttat tcgattatct cattgttggg aatagcaaaa catcccgaat
       61 tgattgtgca tcagttagca acattactaa tctgtcgatc ccgatgccta gaccaccagt
      121 tggcggcata ccgtattcta aggcttccaa gaagtcttcg tctacaccgt gagcttcgtc
      181 atttcctagt tcacgttctt tttcttgcgc ttcgaatctt tctctttgat caattggatc
      241 gttcagttct gtaaaggcat tagcaaattc gcgccccact atgaatagtt cgaatcgatc
      301 tgtgaatcga ggatcttctg gatttttctt cgctaaaggc gaaacttcga ctggatgtcc
      361 gtatacaaac gtcggttgtg tcaatgtttc ttcaacaaat gtttcaaaga attcattgat
      421 aacatgtccg acacccatag cttcggttac ttctacattg tgtttttcgg ctaaagctaa
      481 tgcttcttcc aatgtcattt cttgccagaa gtctacacca gtttgttctt tgattgcatc
      541 taccatatgg atgcgtttaa agtcactttc taagtcgaca gcttgtccat catatgtgat
      601 ttttgctgtt cctagtactt tttcagctgc gttacggata ataccttctg tcagattcat
      661 tacatcattg aaatcagtat atgctgtgta tgcttctaac atcgtaaatt ctggattatg
      721 tgtagtatca attccttcat tacggaaaac gcggccgatt tcataaactt tttccattcc
      781 gccaacaatt agtcgtttta aatgaagttc tagcgcaata cgcaaatata aatcaatgtc
      841 cagtgcatta tgatgcgtga taaatgggcg tgcggcagct ccacctgcct cattgtgcaa
      901 tactggtgtt tctacttcaa tatagccatt gccatctaaa tagcgacgga tttcgctgat
      961 aatttggctt cgtttcataa atcggtcaaa gctttcgcga ttactgatta aatccaagta
     1021 gcgttgtctg tagcgttgtt caatattcgt taagccatgg tatttatctg gcagtggacg
     1081 aagtgctttt gacaaaatcg tgatttctga agctttgata gaaacttcgc ctgtgtctgt
     1141 tttcatgatt tgtccagtta caccaaagaa atctccaagg tctgcatgtt tgaatacttc
     1201 ataggcctca tcacctactt ggtcttttct tacataaatt tgaatttggc cttcacgatc
     1261 ttgtagatgc gcaaatccag ttttcccttt tcctcggcga gtcatcatac gaccagctac
     1321 actagcggtc aatcccattt ctgctagttc ttcttttgtt cttggatcaa atagttcatg
     1381 caattcttct gagttgtgcg tgcgttcaaa tcgttttcca aatggatcga ttccatcttc
     1441 acgcaattgt tccatttttt gacgacgtac aagcatttga tcatttaaat cttctacttg
     1501 atgttgttgt tcctgtgtca caaaagttcc tccattctca tgttaatctc tttcctataa
     1561 tgccaatgaa acacaaaaaa agcaagccga acttggaatt tcggcttgaa aattcacgaa
     1621 aaacttagaa atcacaacgt ttgtttcaat agtacttttt ccgctttttc tacaaattga
     1681 tccagcaggt cattgatttc ttgctgtttt tctgtctgat tgattgctac tttcactttc
     1741 gctgctcgag gaatcccttt taaataataa gccgcatgtg ttctgaattc tctacaagct
     1801 actttttctc ctttgagatc tgctaagcgt tgtaaatgaa gtttagctgt agcaattttt
     1861 tcggctggtg ttggttcagg aatcagttct cctgtttcga gataatgctg tgtgcggtga
     1921 atcatccatg gattgcccag cgctgcacga ccaatcatca caccgtctgc accgacatag
     1981 tcaagcatcc attttgcatc ttctggcgtt ttgacatccc cgttccccat aaatgggatc
     2041 gtcaaatgtt ttttcacttc tttcaatact tcccagtccg cttttccttc atacatctga
     2101 acccgtgtac gtccatgcat agcgatggca cttgctccag ctgattgtgc tgctaatgca
     2161 ttttctacag caaagacgtg ctcttcatcc caaccaatac gcatcttgat tgttactggg
     2221 atatttactg ctgaagaaac agcttggacc atttcgtata ctttctcagg atctaaaagc
     2281 cattttgctc ctgcttctgc tttgattact ttatttactg gacagcccat attgatatct
     2341 attatatcgg cagctgtgtt ttcttcgaca aattgagcag cttcaactag actatcttta
     2401 tttccgccaa atatctgtaa acttaatgga tgttctgttt cttcaatgtg gagcatctct
     2461 aaagtttttt tgtttctgaa atgaatacct tggtcactga tcatttcaca tacgactaag
     2521 cccgcaccaa attctttgac agtgactcga aatgctgaat ttgttattcc agccatcggt
     2581 gcaacaacga cacgattagg gatttccaca ttgccaattt tccatgtgtg ttccacttaa
     2641 atccctccta aggcttcttt cttcaatcca tctaattctt cttcgctata cttgtatttg
     2701 ttattacaga aagaacaaac cgcttctgca ccgtgatctt cgtctatcat tgcttggatt
     2761 tcttctgcac ctaacgcgat aattgcttct gcaaattttt cttttgaaca gtcacatttg
     2821 aattgaacag gcattttttc caaaatgttc aattcttctg taccaagcaa tcctttcaat
     2881 atttcttctg gtgtctgtcc ttcatctaag agggtagaga ttcttggtgt cgtttttaat
     2941 tgttcttcga tcttgctgat tgtttcttca tcggcacctg gcatgatttg gatcatgaat
     3001 cctcccgccg tcttgatgct gtcgtcagta ttgaccaata cactcagtcc aacagctgaa
     3061 gggatttgtt ctgagatagc aagatagtaa gtaaaatctt cagcgatttc tccagaaaca
     3121 atcggcgttt gcccagaaaa aggttctttt aatcctaagt cttttgtgac agtaaacatt
     3181 ccttgtgttc caactgctcc ccgcacatcg attttacctt cactatttag aggaagactg
     3241 agatgcggat ttttgatgta acctttcaca tctccctttc catttgcatc tactacaatt
     3301 cctgttgctg gaccatcgcc ttggattcga acagttagtt tgtcttctcc tttgagcgtc
     3361 gcaccaagta gcagactacc gaccaatgtc cgtcccaaag cagctgagga ggtgtgccaa
     3421 gtatcatgac gtctttgtgc ctccgctacg gtatttgttg cttgaacggc gtatgctcgg
     3481 acgaatccgt cgtgagcaag tgccttaacc aaataatctt tcatttgtta tgtactcctt
     3541 tttccgtttt taaactcata gtgaatcata ctagcaacta ctgctttttt caactttgga
     3601 atgcttcttt taaaaataat tcagaatcat ctagaaaaca ggacatcacc ctatttacaa
     3661 cttaaataaa gaaatctccc gaaaaccggt ttttgttccg gttttcggga gtcatatcag
     3721 atcaattgac ctatattttt ttatttgtat tgatcgtctg aatgattatc ttctgattgt
     3781 tgagaatctg aatcatgttc tgctttattt tcctcattca gttcatgttt tgcttcttca
     3841 aaatcacgtt tttcttccgc ttgtttttca gcgtcttttt cttccaaagc acgttttgct
     3901 tcttcaaaag ttttcgcttc tttttcgctt ggataatcat ttgactcagt accttcaggc
     3961 atcacaccgt gttcaaacaa tgacttgatt gctttggcat ccaatgtttc gaattccaaa
     4021 agtttttcag caatcagttt atgctgtgca cgatgagctt cgatgatttc tcgagcttta
     4081 tcatgagctt ccatcaagat ttttcgtact tcttgatcaa tctcgaaagc gacttgttcc
     4141 gagtaagctt ttgtttgacc atagtcgcgg ccaacaaaca cttgatggtt tccttcatat
     4201 tgaacaggac ctaaacgatc actcattcca tattctgtta ccatgcttcg tgctagagct
     4261 gtcgcttgct caaagtcatt ggaagcacca gttgattgga cattgaagat gatttcttca
     4321 gctgtacgtc caccaagtaa gcctacgatt tgttcaaaca tatcttcttt cgtcatcaag
     4381 aactgatctt cttttggtaa agcgatcata tatccgccgg cgcgtccgcg agggatgatc
     4441 gttactttgt ggacgacccg agcgcgactc aatactaatc cgacaatcgt atgaccagct
     4501 tcgtgataag caaccatttc gcgttctttt ttgctgatta cgcgatcttt tttagctgga
     4561 cctgcaatca cgcgatcttc cgcttcatcg atatcagaag catcgatttt ctttttattt
     4621 cttctagcag ctactaacgc tgcttcattc aagacatttt ctaaatctgc tccggcaaaa
     4681 cctggtgtct gttgagccac aactttcaag tcaacgtcat ctgccatcgg tttattccgt
     4741 gcatggactc gcaagattgc ttcacgacct tttacatctg gacgtccaac taaaatctgg
     4801 cggtcaaaac ggcctggacg tagtaacgct gggtctagta catcagaacg gttggttgca
     4861 gcaatgacga ttactccttc atttccgtcg aagccatcca tttctacaag caattggttc
     4921 aatgtttgtt cgcgttcatc atgtccgccg cccataccgg caccacgttg acgacctacc
     4981 gcatcaattt catcaatgaa aatgatagct ggtgcgtttt tcttcgctgt ttcaaacaaa
     5041 tcacgaacac gacttgctcc aacaccgaca aacatttcta cgaaatcaga acccgagatc
     5101 gagtaaaacg gtactccagc ttctccggca acagcttttg ctaataaggt tttacctgtt
     5161 cctggaggtc cttctaaaag tacacctgcc gggatacggg cacctaattc aacaaatcgg
     5221 cgaggatctt tcagaaattc aacaacttca actagttctt gtttttcttc ttccgcaccc
     5281 gctacatcag aaaaacgtac gcgattagct tttttgtctg cttctttggc ttttgattta
     5341 ccaaagttca tgacacggcc gccaccgcca ccgccgccgc cttgttgtcc catcatcatg
     5401 taaaagaaaa agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata
     5461 ccgctgcttg attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt
     5521 acttggctca atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta
     5581 tctgttgaac ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat
     5641 tcaccagtga tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct
     5701 gcttgtagtt gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta
     5761 ccaaaaatga aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca
     5821 tttttcatca tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat
     5881 ttaacagttt tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc
     5941 attaatttga ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg
     6001 cttctgcata atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat
     6061 aatctgcttc gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga
     6121 ctgattttgc tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt
     6181 caatgatatc ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga
     6241 cgatttttac ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat
     6301 ccaattccaa atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt
     6361 ttaagacacc tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta
     6421 gttctttgca acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt
     6481 ccaacatcag gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg
     6541 tattttatca gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata
     6601 tatatttctt ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt
     6661 ctgatcgata aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc
     6721 tcctgctttt cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga
     6781 aaatagagac catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc
     6841 aatccattct gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc
     6901 ttctgtctgg ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct
     6961 tttcagtatc caattattgc caatactgag ttgccattgg ctttttttct gttgccactg
     7021 gtctaaaatc gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt
     7081 gtcgaaaaag gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc
     7141 tgcagaaaat cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat
     7201 atatttttga atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct
     7261 caacgcctgt gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct
     7321 ctggatatct aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc
     7381 ataagtatat aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc
     7441 aaatggttgt acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt
     7501 cattaacacc gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg
     7561 tccttcttcc atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat
     7621 ggcggatttg gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca
     7681 atatgagcga agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg
     7741 gacgatacct aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac
     7801 catcgaatca acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc
     7861 ttgttcattc ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt
     7921 ttcaacgttc atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct
     7981 aaaacgacaa ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta
     8041 tttgcggctt tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc
     8101 ttcaatgaag ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag
     8161 tcttcttttt gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt
     8221 cggttgtcac ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca
     8281 gcaggttgtt cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa
     8341 ataactttaa ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag
     8401 ccatttgaca cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac
     8461 gcaccaaaat ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac
     8521 ataaaaaaaa tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt
     8581 gtagaactag ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata
     8641 ggataaactt tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca
     8701 tactcatcat ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact
     8761 tctttcattt cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg
     8821 tcatggaaaa tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca
     8881 gccagtctgc gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt
     8941 ttctttgcat attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt
     9001 cgctccaatc tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc
     9061 tatttctcta gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct
     9121 tcttttttgg ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac
     9181 tggactttca aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg
     9241 atttgaattc ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg
     9301 gaaattttta aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt
     9361 taatcgcagg attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg
     9421 aagacgaatc actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac
     9481 aaaaaaagca gtggaacgat gagttacagg accaaatact atattcaata caccataata
     9541 cagcagcagt actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg
     9601 ttctttccaa aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac
     9661 acctaatcct aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa
     9721 agaagtagtc aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa
     9781 cgagttcttg ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga
     9841 aaaaacaaat aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat
     9901 ataagggagc agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct
     9961 aagatagatt ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt
    10021 caacgcaggc aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa
    10081 aggctgacct cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta
    10141 aacttccaaa gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc
    10201 actataaatc gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg
    10261 ctgtttgaac aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata
    10321 gtagtgaagg atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt
    10381 ccctgtttgg tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac
    10441 aaaaacacga acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct
    10501 tccttggaaa ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac
    10561 tacttggatc agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa
    10621 tgcaaagaca aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg
    10681 caaagcttgc tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg
    10741 cggaagaccg gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata
    10801 aacataaaaa ccttcgtcgc ctactaagtt ttggagggga attcggtaaa gggcacttaa
    10861 tacttttgct atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat
    10921 ttctttatga tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac
    10981 gctttgacaa acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc
    11041 gtcaagcgta tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct
    11101 gtcagtgctt cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta
    11161 aagactatat gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt
    11221 ttgatctgcc caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg
    11281 agcagatcat cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta
    11341 tagatctcga ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca
    11401 ccgaggtcga tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa
    11461 acagcttcgc ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc
    11521 tgctgagcac ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg
    11581 aatccagatc ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg
    11641 ttaaggatct tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct
    11701 acccgccctc gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac
    11761 aacgtatttg cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca
    11821 tcatattgac cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc
    11881 ccatgagcat aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt
    11941 tcgatcgttt ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga
    12001 tggattgctt cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa
    12061 cgattcgcag gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc
    12121 aaagttctcg gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt
    12181 ttcaatcgtt ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc
    12241 aaatcgctaa attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact
    12301 tgacctgtac gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt
    12361 aatagcccga tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc
    12421 tgtgccaaga tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta
    12481 aaggccgctc gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga
    12541 tccattggtt tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca
    12601 tcagtttcag agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca
    12661 aaagcatatc ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata
    12721 tcctcgattt ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta
    12781 ttgatgcgag gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta
    12841 acaggaataa acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg
    12901 ccatctactt ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca
    12961 acgtaatctc ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt
    13021 tgacgtctcg tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact
    13081 attttttctt gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt
    13141 cctctgatca atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt
    13201 tgttctgctt tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc
    13261 ttgcgccaac ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc
    13321 gtccgatatt gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag
    13381 agtgagaaaa aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa
    13441 aatgtctgct cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct
    13501 tccctttcga tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa
    13561 ctatttgaag ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag
    13621 aattttgctt cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa
    13681 tcttgcaaaa actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt
    13741 ttttgcattt gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt
    13801 ggggaaaccc agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac
    13861 cgcatagaat ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac
    13921 gggtaaatat cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct
    13981 tctcgtacat agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca
    14041 ccaatatgcc aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc
    14101 aaagatgcga ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt
    14161 gcaactctct cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca
    14221 tccactggaa ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac
    14281 tgattcgcat aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac
    14341 gctcgagcaa atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc
    14401 attttttctt ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga
    14461 ataatatcca ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga
    14521 atgcccttct atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa
    14581 aggctgattt tctttgctga aaggactaag cacatgctgg actactgctt ttttcccttc
    14641 tggcctgccg attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat
    14701 acttttgata ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac
    14761 tgccagatcc aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt
    14821 cattagtggg ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag
    14881 gatcttttct ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa
    14941 agtagcttga tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt
    15001 atattggtat ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca
    15061 cctaattcta aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag
    15121 cttttttctt ttttatactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta
    15181 aaagagaatc gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata
    15241 attgatatat aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt
    15301 gttatctgtt atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata
    15361 agcatgggaa aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa
    15421 aaaagatcat caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt
    15481 tgctctagtt actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa
    15541 aactgaagga gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat
    15601 ctattctgct acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc
    15661 accacaaaaa ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg
    15721 cgatgttgtc acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa
    15781 cccagtagat attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt
    15841 aatcggttca ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt
    15901 tgacgttgat gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt
    15961 cccagtttgg tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa
    16021 cccagaaatc gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta
    16081 cacaattatc gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat
    16141 cactcgtgcc atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg
    16201 cgaatatgga ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat
    16261 ccaaaaagta atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc
    16321 taagcaatta aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt
    16381 gaacatgacg gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg
    16441 tttctaaatt ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc
    16501 atgagaccgt tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc
    16561 atcgaaaaaa atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga
    16621 tcagctttta tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa
    16681 taaatggaat aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag
    16741 cttattctga taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa
    16801 aatccgagct cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac
    16861 aaaacggatg gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc
    16921 ctgtcagtca aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga
    16981 ctgatttgaa caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact
    17041 ctttcgttat caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac
    17101 aattaaaaag tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa
    17161 aaccaaaagt aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta
    17221 tcgcaaatgt aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg
    17281 atattatgag ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac
    17341 gtcaatatgt aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta
    17401 aaagtacaaa aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa
    17461 cagacagtga gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt
    17521 cacccattgt gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg
    17581 aagttgatct ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa
    17641 cagatatcgt ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga
    17701 ataaagaaga agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc
    17761 cggtaaacta ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc
    17821 aacctgaata cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc
    17881 caccaagtgt aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct
    17941 tctaacaaaa ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt
    18001 ttattatcta acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat
    18061 catcgtcttc tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat
    18121 caatcgtcgt ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca
    18181 actcatctcg tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag
    18241 aagtttgcag atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa
    18301 cagtcaaccc atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg
    18361 aacccgtttc tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg
    18421 tccgattacg gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc
    18481 cttcatacgt gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg
    18541 cccgttccac attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca
    18601 aagctggatt catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag
    18661 aaagtttctg aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat
    18721 tatgccattt actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt
    18781 ctattctagt actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga
    18841 atgccgcaaa aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga
    18901 catcttggaa cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg
    18961 cgtaccctgt tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg
    19021 ggaaaacacc taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct
    19081 tccttaaaaa gaactctaaa aatttggcgt agcccagatg gtcgatactc accatacttc
    19141 caccataatt aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc
    19201 tttctaatcg cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga
    19261 ttataacgac tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg
    19321 aagaattcat aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca
    19381 ttttcataga gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa
    19441 gggagttttt tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc
    19501 agtcattctg atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat
    19561 tatcaccgcg taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt
    19621 cttcaattgc aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca
    19681 ttgctttctg ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca
    19741 atgctgcctc gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct
    19801 gacaatgatt ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta
    19861 aacgagattc gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat
    19921 acgctttctt tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc
    19981 atttcgattc ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc
    20041 aataagatga tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa
    20101 gaagcctgga aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt
    20161 agactttctg actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac
    20221 aatcggttga agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa
    20281 ccccttgtta attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg
    20341 caagatcaag atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac
    20401 gaagcagcag catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt
    20461 gcccaatctg cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct
    20521 ggtggttatt gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt
    20581 aattctgtta atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc
    20641 acgatgtggg atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca
    20701 agtacattcg cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa
    20761 gaaaaaatca atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc
    20821 cattcccgat tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca
    20881 gaagataaga tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta
    20941 gctacttacc atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg
    21001 ttttataact tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc
    21061 aaccaaaagg gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca
    21121 atgacgacgg aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt
    21181 tggcaagcag gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa
    21241 gaatttatct gatttctatt ttatcacaat aaaaaaagag ttagtccaga atgggctaac
    21301 tctttttgat taatcattct tacatgctga cagcaaagtc aggggcaaac cattgaactg
    21361 aaccaacttt tacgctttcg cctggttgag gagcatggat atattgtcct ccgcctaaag
    21421 caatcgctac gtggtaagtt ccgccttgtg acccccagaa taacaagtct ccagcttttg
    21481 cttgagaaac tgaaattttt gttccagctg attcttgagg aactgtccaa ccaccgatgt
    21541 cacgaccagt tacttgcatg taaacatagc gtgtgaaccc tgagcagtca aagccacttg
    21601 gatctttacc gccccaaaca tatggagtac caatatattt gtaagcttct gctacgattg
    21661 ctgcaccatt cacacttcca gaaggagctg gagcaggtgt tacaggtttt ggttgttcag
    21721 gtgttggtgt tggcgttgga gccggagtac tacttcctgt gccgtttcct gtatcaacac
    21781 tttgatctgt tgatggtgtt gtaggcgcag gtgttgttga ttcttctgtt gttgaagatt
    21841 caggcactgt tgttgattct tctgttgctg aagattcagg cactgttgtt gattcttctg
    21901 ttgctgaaga ttcaggcgct gttgttgatt cttctgttgc tgaagattca ggcgctgttg
    21961 attcttctgt tgaagattca ggtgttgttg attcttctgt tgctgaagat tgtgtagctg
    22021 atgatgattc ttcagtcatt gaagattgtg tagctgatga ttcttctgtt gctgagcttt
    22081 gtgcagtaga tgaagcttga gtagcttgtg cttcagcctc tgcttgttcg cgtgcttctt
    22141 tttcagcttt ttcttgtgca gcttgttgac gagcttgttc tgctagacgt tgttgttcac
    22201 gaatacgagc ttgctctgct tcagcttctg ctttttgacg gttcaagtca gctttcttgt
    22261 cttcagcagt tgcttgttca gcagctaatg aagttttcag tacgttcaaa tcagcttgtt
    22321 tagataaaag atcgcctttt tgagattcca aagcagcttg gttttcagct aattctttta
    22381 gtttagcatc gttttcagct tttttgtctt ctacagcttt tttatcttgt ttttgttgtt
    22441 ccatcaagtc gttgtttgct tttaccatcg ttgtcattgc ttgaacgcgt ccaatagcat
    22501 ctgctaatga atcagcattc aatacagcat cgatgtagtt tgagcttgtg ttgcttactt
    22561 gtgcttcgcg tgcttgtttt tggattgtat cttcacgttt ttcaatacgt tcttgtaaat
    22621 ctgcaatgtc ttttactaat tgtgcagatt cttgacgcaa tgtatcttgt tttgctaata
    22681 ggtcttgtgc ttgtgtgttg atttcagaaa cttggctttc taaggcatcg atttgtgatt
    22741 gtgcatctgc ttgttgattt ttcaagtctg caatcttttg atcttgctgt tgtatctgag
    22801 aatcaaaatc gtccgccgcg gcagcgatcg gtgatgctac ggcagtcaag gtcattgaac
    22861 ataccattac tgctgatatt aaactctttt tcactcttca ttcctccgac tggcttaatt
    22921 taataaatat ctaaatatat ttaagtcttt cttaacgata taaaaattgt accatagcag
    22981 tgtgtcaacg atataatagt tatgttacaa aaatgtttca aaacaacttt taaaaatgac
    23041 aaaactgttc gtttcagaaa atgatcatga aaaagccgcg ttaagtctag catttcttaa
    23101 gataacaacg attctttttc gctttcgacc taaaaataaa aaaagaaatt attcatcact
    23161 gaataatttc ttaaagggaa aaatgaataa tacaaatata atcatgttca acagcagtgt
    23221 aggtcctaaa aaccttgtaa taaaatacgt gttatttact actgctaatt taaaaatcaa
    23281 ctggaccacc atcgtaaaca attcataacc cgtgacaaag atgatcatac tgaaaaattc
    23341 agtaaagatg ttgacatgga taacgtcttt cattacatac atcaaccata caattaaagg
    23401 gagagctact gcatagatac cgataacgcc aatatagtaa gcgtcataga tagccccgag
    23461 aacaatcgtg gtaatcagta aataacgttt ttcaaacgcc atactgcaac ataataatgc
    23521 caatatcaga aagtgggcat ttgacatata ggtgcctttc gaccactccc ctagcattct
    23581 tgttaaatga ccatctatca acatcaaaaa gaacaaaacg attggcagat agtacttcat
    23641 tgtttctttc ttcaacatgg actaatcctc cgctagccgt tggacaatcg tcacaactga
    23701 cacgtcatac atttctgcat aaggtttcac ataaacttcc cgatccagcc cataactatc
    23761 tggtttcgtt ttaataaccg taccgatcgg caagttagct ggagaattcc ctccaagacc
    23821 ggatgtctgg acaacatccc cttctttgat atccgtatca ccagttaatt gggtcaccac
    23881 taaggcatgg agcttttcat catagttttt aagcaaacca aacgcttcgc cattagccga
    23941 agatacccgt actggaaaat gattggagct ttcattagag gatgacagta attcgatttt
    24001 agacgaagcc gtattgacct cgatcactcg gccaatcaat cctttttgcg acatgactgc
    24061 catatttgct tcgataccgt ctttagaacc cttgtctacg atcagcatgt cctgccaact
    24121 gtcaggcgaa cgagtaatga catttgccgt tactttttcg taactagtca gcgtctgatt
    24181 caactcaagt tcttttttca acgcttcgat ttctctctcg taattcttgt tttgctgtga
    24241 aacgtcatca tagctatcga ttttttcttt tagccgctca ttttcggcat aagttgaaaa
    24301 aagattatgg acagaatcta ctccatttcg tacccaccgt actggggcag agattgtttt
    24361 atcaaccatt gcaacactgt cattaacgat ggattggaag aaattgggct ttccttcatt
    24421 cgctcgctgc gcagcggtca cacttagtat cgtcaccacg atgataacaa taaccaaggt
    24481 aataataata tttttattag gattgaactt cttcacaaag acacctcgaa ttaattagac
    24541 tcttgtgttc aattttatca ctaaatgccg tgaaacaaaa ggtaagttgc tcctcttaag
    24601 ctttttttta gcaaataata gattctgtca tttttagcct gaaagacaaa tttttttatt
    24661 tgtttatgga tcaatctttg ctttgaataa ctgcaatcat accatctgaa aaagaaaatt
    24721 ctgcggtatc tgaaagaaat tcgttacttg cataagatgt cggatattct acttctttat
    24781 tttccaatac atacttgctg ccttttaatg taagattcga gacgggagtc aagcagcaat
    24841 aagctaaata cttcatatct ggtatctgtc ttactatatg ctctccaggc aaataataag
    24901 acaaataatt ttgacaatct ctgataataa gctgatgggc aaagggtttg aagcgaggtt
    24961 ccatacctaa ccagagattg gctaaaagat gatccaatct tccgcccgta gctccaatca
    25021 aagtgacttc cgcttgcggg taacgttcaa atgtttttaa gatacctaac tgtgtatctg
    25081 tatcgtcttt ttctgcaggg gaacgggtat actctttggc ttttgcaaat acttccttct
    25141 gctcttcgtt cgacaatgaa tcaaaatcgc ccactgccag atctactggg tagcctgctt
    25201 gaagcaggta cagcgcacca cggtctatcc cgacataggc atcgtatttg gacagcagag
    25261 actgcggcca gttttgcgga ttacctccag cagctaataa aattttcatt tagtctaatg
    25321 cctcttttaa tcgttcgatt tgtccgactg gattttcggc tccatagata tatgatcctg
    25381 caacgaagac atccgcccct gcatctttac agatttttgc tgtttctgga acgattccgc
    25441 catctacttc gattgcataa gtccaattgt tctctctacg tagatcagcg agttccgtaa
    25501 ttttttctac tgtttcttca ataaagcttt gtccgccgaa cccaggattg acagtcatga
    25561 ctagtacttg atcagccaaa ggcaaaacat gtttgatcat ggagactggt gttcctggat
    25621 tgataactac tccagcttta actcctaagc tttttgtcat ttgaagtgcc cgatgaatat
    25681 gaggagttgc ttcgacgtgg acagtaatga tatctgctcc agcttttgca aatgctggaa
    25741 tgtagttttc tggatcaacg atcatcagat ggacgtctaa cggtaattta gtaacaggac
    25801 ggattgcctg aacaatattt ggccctaatg tgatatttgg gacaaattgg ccatccatta
    25861 catctacgtg gatgtaatct gcgcctcctt tttccactaa ctcaatgtct ctttgtaaat
    25921 tggcaaaatc tgcactcaaa atggatggtg ctatcttcat tcttgtttcc tcctattttc
    25981 gtttaccttc tttttttgca tacattggtt ttcttttttc gatttcttgt aagaattgca
    26041 aataattgtc gtaacgtgtc tgtgcgatac cacctgtttc tactctatgt tttacttcgc
    26101 agccaggttc tttagcatgc atgcactctc taaatttgca atggacagaa gcttctacaa
    26161 attcaggaaa ttgtctcggc agttctcctg cttcaattgt caaaaagtca atcgagctaa
    26221 atcctggtgt atctgctact aacccgccat agataggaat cagttccaca tgacgtgttg
    26281 tatgccgtcc tcttccaagt gcatcagaaa tctctcctgt tgctaaattc agttccggtg
    26341 atatttgatt cagtagcgtc gattttcctg ctccagactg acccataaag accgatagcc
    26401 gttctgggaa gtaacggatc agttctgtcg tatcacccgt atgattgggt acaatcaccg
    26461 gatagcctat tttagtatag gtttgcttga tctcttcgat tttttctggg tcgtctgaca
    26521 agtcggtctt tgtcaaaaaa ataatcggtt cgatcgactc gtattccaag gtaactagaa
    26581 agcggtcaag tagattataa gaaaatgcag gctctacgat acttgtgaca atgattccaa
    26641 gatcaacatt tgtgactggt gggcgaacta attgattttt tctcggcaag atttccagaa
    26701 gatagccgtc tgtttgattt tcactctcaa agatcacctg atctccgaca agcggcgtga
    26761 ttttccgatt ccggaaattt cctcttcctc ttgtttgata ggtctctccg tttgcgtata
    26821 catagtaaaa accgctgatt gcttttctga tttgtccttt gataagtgcc acctccgttt
    26881 ttgtttattt taccatacga agaggaaagt aggtgttatt ccatgcaaac ttctcaaagt
    26941 atatggcttg aaaattgatc aaaagagata gaaacacaaa aaagagaatg caacaaatca
    27001 atgtcgcatt cccttctgat atattttatt cagcacttat tttgaacttt ctgaggtgct
    27061 agctgatgaa cttgtggagc tggaagattc ttctcttgaa gagttgcttg tgctactgga
    27121 gctacttgag ctgctagaac tgtctgaaga gtctttttca gaactagaag acgctggatc
    27181 tggtccttta gagtaaatta cgttcacaac cattcctttg gtaattgtcg ttcctgcccc
    27241 tggtactgta cgaatcactt tatctttatc caccgtgttt gaatattcgg aagtctcatg
    27301 cccgatatat tctgcaccga cactagctaa ataactttgt gcttcgcttt ttgtatagcc
    27361 ggagatatca ttcaatttag gctctgttcc ttggcttacg acaaaattga tgtaagtttc
    27421 ttctgctaca acttcacccg aggctggatc ctgactgatg atcgaacctg atggtacagt
    27481 gtcgctatag tcataagtag cactaatatt attgatattg aatccttgtg taacaagcca
    27541 attacgaaca gtttcgtagt tttctcctac atgactactc aaagtcactg tttctggtcc
    27601 tttgctgact gtgaaagtaa tcgtgtctgt tttaggatcg acttctgtat cttctgatgg
    27661 agattgcgaa atgatcattc cgctttctac ctctgaactg aattcctctt ctttttgaat
    27721 caagtcagca gaaaacccta attctttcaa acttgcttcg gcatcttcat aacttttacc
    27781 actgtaatca tctaatttga tttttttcgt gccgctacta atatacagag tgacttcgcg
    27841 tttttgcttg actgtcgttc ccgctgccgg gtctgtcttc actacattac cttcttcgat
    27901 tttgtcatct gcaatttctt ctgtttttgt tgctacttct aatttcgctt ttgcgagtgt
    27961 ttctctagca gaagcttcag aaagatcaga aacatcagga acaacaactt ctcctcgccc
    28021 gccagaagca aagaatacag ctgttccgat tcctaaaaca gcaagaatag ctaataggat
    28081 cagccaccat tttttctgtc ctttcttttt aggatcaggc agaacttctt cctcctctgg
    28141 caaggtttcg ttttctggct tgtcttttgg cagaggcata gatttgaatg aatcaggcat
    28201 tggtgcatct tccgtaaggg gtgtgataac ttttgtttca ttatccatca catgaggctg
    28261 ccatttttct tcgtttgcac gagctggtga taatactgta gaaagatcat cagacatttc
    28321 ctcggctgac ttataacggt ctgcaggttc tttagccgtt gcccgtaaaa tcacgttttc
    28381 cagtgcttgt ggcacatttg gatcaagtgc ttttatagat ggaagatcat cttgaaaatg
    28441 ttttaaagca attgttacag cagattcacc atcaaacggt acgctacccg tcaacatctc
    28501 ataaaggatg atccctaaag cataaatatc tgactgcttc gttgccatac ttcctctggc
    28561 ctgctcaggg gacagataat gaacagatcc cagcatcgta ttcgtctgcg tgatcgatgt
    28621 ttcagataaa gcgatagcaa tcccgaaatc cgtgattttt acaacacctt cattatcgat
    28681 cagtacgttt tggggtttca aatctcggtg gatgatttga tggttatgag ctaaagaaat
    28741 agcagaaagg atctgctgca taatatttac tgctgtttca taaggaacag gataatgtgt
    28801 ttggatatat cgtttcaagt ccattccttt gacgtattcc atcaccagat actgcatgtt
    28861 gtcttcttca ccaacatcgt aaacactaac aatgtttgga tgaacgagtt ctgttgctgc
    28921 taaagcttct ctctgaaatc gtcgaatcgc agtctggtca ttttgaaagt caaatcgtaa
    28981 gactttaact gctacatcac gatccaagat taaatcgtgc gccaaaaata catttgccat
    29041 accaccgcta ccgatatttc cagtgatttg ataacggcca tttaattttt tgcccaactc
    29101 gatcatacac tgtcctcctt atattcgata agaagaacgg tgatattatc cgctccgcct
    29161 gcttcattgg cacgatcaat cagctcagtt actttatgag acaatgggcc ttcttgattg
    29221 atgatcgttc ctatttcttc ttcagacagc atgttcgtca agccatctga acataacagc
    29281 agtcgatctt ttagttgcca aagatgagta gaaacatcta cttcgactgt tccaggcatg
    29341 ccgacagaac gtgttaaaat atttttcctt ggatggttca ctgccatttc ttcgctgatt
    29401 tctcctgatt tgactagttc attgactaaa gaatgatcct ccgtcaattg catgatttta
    29461 tcttcacgaa tcaaataagc tctgctatcc ccaacattgg caatcgtgaa ccagtcatct
    29521 gacagagcgg ccgctacgat tgttgttccc ataccgttat attccggctg ttcttgtcca
    29581 cgctgataaa tcagcatatt ttcttcttga atcgattgaa tgaaccattg ggcgattttt
    29641 tcatcgtcaa cagcttcttg tttttcccaa gcttcgccta gattcgttac cgccatctga
    29701 ctggcaatgt ctccggcacg atgaccaccc atcccgtctg ctaatacagc aagcttgaga
    29761 cctgaacggc tggtaaatac actggcatag tcttgatttg tgttacgtcg tcttcctaca
    29821 tctgattgat attcaatctg cattttttca cctcattact ttttgcgcaa acaacaaatg
    29881 aaaaatccat ctgtgtaaaa ctgatgcgga tacaaagtca acattttctc ttcgattgat
    29941 gattgtagca taggattggt caaaacatca atcctctcaa aatcagggtg tctttccaag
    30001 aaagcagaaa caacgtcttg gttttcttct tttaagatcg tacaagtgct ataagtcaga
    30061 ataccggaag actttaaagt tggtgcgcag ctttctaaaa tttccaattg gatttttggt
    30121 aaattcgcta attcatccgg ctgtttttta taacgaatat ctggttttcg ccgaagcagc
    30181 ccaagacctg aacaaggcgc gtctactaaa atccgatcaa actgctctgc ttcgaactgt
    30241 ttactgactt ctctagcatc catcttttga gcgtagacag cagaagagac acctagacgt
    30301 gctgcattat cttcaatgag tttgactttg tgttcgtgta catctaaagc gaccacttct
    30361 ccaccgcatg acggatctaa aaaagaagca atatgcgtcg tcttacctcc gggtgctgca
    30421 caggcatcta agacatgatg ttcaggctcg atttgcatag acggcgctac aagcatcgaa
    30481 ctttcatctt ggatcgtcat gacgccatcg tggaacaatg agctagaagc taaatgccct
    30541 tttttcgcta ctataccgta tggactgact tggctttttt cagctgtgat ctcttcttct
    30601 tgcaaaacag tgatggcctg atctctggaa agtcggcgtg tatctactcg ggcactagca
    30661 tggctaggct gatatagcga taaaccgagc ttttcagttt cttcgtatcc gatttgatcc
    30721 accagtcgtt tcgtcatcca tagaggcagg ctgattttga cagaaagtct ttcgatagga
    30781 tcagcaatgc cttgcagatc tggtgctcct tgacgctgat aattcctcaa gacaccattt
    30841 acaaatttcc ctgtcccagg atttcctttt acttttgcga tttcgaccgc ctcgtttaaa
    30901 atagcatgtg cagggacttt atctaaaaat tctaattggt atacagaaag ataaagaagc
    30961 gtcttgaccc agtcatccac tttttttgct ttagcgatca atggtgcaac gtaaaattcc
    31021 aatagtcgct gatggctaat cgtaccatag atcaattctg taaataaacc cacatctttt
    31081 tgatttagct cgctttgttt gatcatctca ttcaacaaaa gattcgagta ggcgccaccc
    31141 ttgttcactc gctctaatgt cagtaatgcc atatatcgta ctgatttttt cattttttta
    31201 gggatttttt tcattatttc acctgctgac caatctgaac ttgctgaccg cttccgttaa
    31261 ggaaatcatg tacggcctgt tttcctttac cagctggctg taattcattg atggctaaga
    31321 cggtctgttt accgcaagca atccatagat tttttttgtc tttccggatg atcgtaccag
    31381 gtgctttgtc tgtagtttct gccaatactt caaccgataa taatttccag cgtatgccct
    31441 cataggtcgt gaatgcaatt ggccaaggac gcattccgcg tacttggttg tcaatttctt
    31501 ctgcagtttt atgccaatcg attgcttctt gttcccgtgt gatgtttggc gaaaaagttg
    31561 cttctgactc gtcttgaggt actggttttt gtccatccaa aatattgggc aatgtttcta
    31621 gcaatagctt tcttcctaaa aggctaagct tttcaaacat cgtccctaca tcatcttgtt
    31681 tagtgattgg tatgctttct tgcgcataga ttccgcctgc atccattttt ttgatcattt
    31741 ccatgatcgt tacaccagtt tctttctccc cattcatgat ggcataatga acaggcgcac
    31801 ctccccgata tttaggaagt aaagaagcat ggacattgat tgcccctaat tttggtactt
    31861 gcaataactt ttcaggcaag aattggccaa atgccgcagt gacgatcaca tcaggcacca
    31921 attcaatgat ttcttccatt tctggcgaac cggagatttt ctctggctgc agcacacgga
    31981 taccgtgctt cagagccgct tcttttaccg gtgtcggcgt aattactcgt ttccgcccaa
    32041 ctggacggtc gggctgtgtt accactgcct ggatctcgta acctgattct atcagccctt
    32101 caagaatcgg cacagaaaaa gcaggtgtgc ccataaatac tagcttagtc atcaagatgt
    32161 tcctccatat attcttcaag ttcttcttcc gggatctgct gtatcatttt ctcaatgaac
    32221 aagataccgt ctaagtgatc gatttcatgc tggaaggcac gggctaaata gccaaaagcc
    32281 gtcacttcta tctcttctcc gtctcgatca taataacgca cggtcacttc atctgctcgc
    32341 ttgaccgttc catagacatg cggaatactg agacaacctt ctacgtcaag gctttcacct
    32401 tttgcttcga tgatttctgg gttaatcagt tcaaatttct cgccttcatc tacttcgatc
    32461 acagcaattc tcttgttttg tcctacttga ggagcagcga tccctattcc gtcattcgca
    32521 atcattgtct catataaatt gtctaataaa gcgattgtct cgtccgtgat tacatcgatt
    32581 ggctgagcag ttctttttaa tttatcatta gggtggatca atataggata gcgcataatt
    32641 tggccctttc ttaaataaag tttaatggtt cgttgtcaat tgccacaaaa agaccttgtc
    32701 gctgttcttt ctggcttcca ttcaaaattt catccaaaac atgaggaaga ttcggttcat
    32761 gtttatattt gatgattagt tgataataat atcggttttt cactctcaaa atcatgctgg
    32821 gcgttggccc taatagcaag ctttgagggc ttaacacttc ttttagctga ttggcaatct
    32881 gaaagatttt ctttgccgct acttgttctt caggatggct ggcggttatt ttcacagtaa
    32941 agtaataagg aggatagcct ccacgatgcc gtacatgcat ttcctgctga taaaactgct
    33001 cataattttg ttttttagct aattctatgg cgtaatgttg aggattgaat gtttggatca
    33061 cgacttcgcc tgctttttcc gctcgccctg ctcgtcctga aacttgggta agcaattgga
    33121 atgtatgctc actagaacga aaatccggta aattcaggga ggtatcagca ttcaacaccc
    33181 caactaatgt cacttctgga aagtccaaac ctttagcaat catttgtgtc cctaataata
    33241 tatctgcttc ttttgcaccg aatttttgta aaatctgttc gtgtgcccct tttcttcgag
    33301 tggtatctac atccatacgc aaaatcctag cttgcggata aagttctcgg agttcctctt
    33361 ctactttttg agtacctgtt ccatagtagc ggattttatt gccgccacaa ttaggacagc
    33421 gattgggaat aggttcttca tgtccgcaat aatggcagcg cattgaacgt gtatccatat
    33481 gcagtgtaag agagatatcg caattaggac atggaagaac aaatccacag tccctacaca
    33541 tcacaaaaga cgaatatcct cgacgattga gcagtaggac agtttgttct tttttgtcta
    33601 atcgattttg tattttttcc tgcaaattag cagaaaaagt agaggtccga tgattctgaa
    33661 actcttcacg catatctacg atctcaatag ctggaagctg tgcagctgct ttggctcggt
    33721 ggtttaactg caataactga taaacgcctt tttgagctcg tgctcttgat tctaaagagg
    33781 gcgtcgcgct tcctagaact attgggcaat gatgatattt actgcgccaa attgctagat
    33841 ctctcgcatg ataacgcggt gtctcatctt gtttgtaact tgattcatgt tcttcatcga
    33901 taatgatcag cccgatattt ttcagcgggg caaaaatagc agatcgtgcg cctactacta
    33961 cttgcgcttc ttcccgctca atcttgcgcc attcatcata tttttcacct tgggaaagtc
    34021 cgctatgtaa gaccgcaact gattctccga agcgtccttt gaatcgctcg accatttgcg
    34081 gagtcaatgc gatttcaggc actaacataa tagccgtttt attttctgac aaaacatcag
    34141 cgattgcctg aagatatact tctgttttcc cgctgccagt gattccctcc agcaaaaaga
    34201 cctgatcttt ttgctgctga cctgctgtga tgatttgttc gacagcattt ttttgttctg
    34261 cattcagttc caatgccgtc gtttggtcaa atactcggtc tttataaggg tcgcgataac
    34321 gttctgattc tataaactcc agccagccct tttcttttcc ttgattcaag acagcagtac
    34381 tgattccttt atttttgaaa taagcaattg gttcttcttg gctcagttca gataaacaca
    34441 aaagaagttc tttttgtttc ttggcatttt gccgtaattt tgcccattct tcttcgattt
    34501 gcttttcagt taacaaagaa cggaccaaac gaatcgtttt tactttattt cgtgtatgga
    34561 cttcatattt gatatctact aattgctctt ggcgccagcg aatcaattga gaaaggctgc
    34621 cttcttcttc tgcttccttc caggaaatca cttctcgctg atcaaacaat acctgaactt
    34681 ctggtgtgtc tgccaaagga tagatcaatt tatcatattc tgctttcatc acactcggaa
    34741 gcatcgtttg tagacaagtg attttgaatg cgtaagtaat ttttttcata taatcagcta
    34801 atgaaagtaa ttcttcattg accaccggag caaggtctag caaacgaata actgccttca
    34861 aagatggatt agctgattct tctgattttt ggatagccat aacaaatcct tggacatgac
    34921 gattgccatt accaaaaggg acttctactc gcatcccgac ttgcaaagct gtttccattt
    34981 cagagggaac caaataagtg aatggctgat cggtctgcat agtaggtacg tccacaatga
    35041 cttcagctgt taatgtcatg gttcgtttcc tccttttttt gtcttttctt atcaagcgac
    35101 aaaaagttcc ttgcctattt tactagagat cgatggattt gtcttatctt ctgccaaatc
    35161 ctaacaaaaa attaacagca gataagaaaa aaaagaactg tgtcaaaaag ttcagacaca
    35221 gccttttcta ccagacaata agtggcgaat gtttgaaaag gaaacagctg ggtttgcttt
    35281 tctttttaga tgttcgctct atttttcttt attacatttt ttgctcttca cggatacgtg
    35341 attccaattc gtgttgttca cgctcttttt gtgcttgacg ttcctcttct tccatcttca
    35401 aacgttcacg ttttaattca ggatgtggat cattgactac atttcctgca tcgatttctt
    35461 ctaaagcttg accgacgctt tttactgaat caaaagaatc tagagtaggc tgtgcacttg
    35521 catccaattc atgcgcgcgt ttacttgcta aaatcactag agaatatttt gaatttacac
    35581 gatctaatag tgagtcaatt gaaggtttta acatcataag actacatctc ctttaacatt
    35641 ttaatatatt taccgattac gcgatctact cgaaaatgtt cactggcaat aatgtttttg
    35701 attcgttcaa ctgctagcgg cacttcatca tttacaacag catagtcgta aagagccatc
    35761 atttcgattt cttcttttgc aactttcatt cgttcttcga ttacttcatc tgcatctgtt
    35821 cctcggccta cgatccgtga ttttaattcc gctaaatctg gcggagtcaa aaagatgaat
    35881 acaccatcgg gcactttttc tttgacttgt tttgctcctt ggacttcaat ctccaagaaa
    35941 acatcttttc cttcatccaa tgtcttgttg atatatgaca aaggagttcc ataataattc
    36001 ccgacatatt ctgcgtattc cagcatctct ccagcttcga tcattgattc aaactcttct
    36061 ttgcttcgga agaaataatc aacgccttcg acctcccctt cacgcatttt acgggtagtc
    36121 attgagatcg aatactgaaa atcattatcc tcactctcaa aaattgcttt tcgtactgtg
    36181 ccttttccta caccggatgg accagacaac acgattaata atccacgctc tgacatgacg
    36241 acgtcctttc aactagtctt tttgtactta tcgtttattt tgcacttttt ttctgcaact
    36301 ttcaaggtta tctttaatta tagctagaaa ttggtaaaaa agctaccctg taccaagagg
    36361 tcgtaaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacataaac agcttctcat
    36421 gtttttcgtt tggttggggt tattatcgca gatgcaagct tttgaacgcc gtgtataaga
    36481 ggtcgtgaag aagccgatta gtttcgagta tgaagaaaaa ttttgtgaaa atagtttctc
    36541 acatttttgc ataaatttgg cttaata
//
LOCUS       DAIGUC010000026        36536 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.026, whole genome shotgun sequence.
ACCESSION   DAIGUC010000026 DAIGUC010000000
VERSION     DAIGUC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.026"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..178)
                     /locus_tag="NOB46_001379"
     CDS             complement(<1..178)
                     /locus_tag="NOB46_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI1058321.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLY"
     gene            382..1032
                     /locus_tag="NOB46_001380"
     CDS             382..1032
                     /locus_tag="NOB46_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI1058322.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            1048..2775
                     /locus_tag="NOB46_001381"
     CDS             1048..2775
                     /locus_tag="NOB46_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058323.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            2772..4664
                     /locus_tag="NOB46_001382"
     CDS             2772..4664
                     /locus_tag="NOB46_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058324.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            5368..6237
                     /locus_tag="NOB46_001383"
     CDS             5368..6237
                     /locus_tag="NOB46_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HCI1058325.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            6446..7471
                     /locus_tag="NOB46_001384"
     CDS             6446..7471
                     /locus_tag="NOB46_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI1058326.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            7510..8460
                     /gene="manA"
                     /locus_tag="NOB46_001385"
     CDS             7510..8460
                     /gene="manA"
                     /locus_tag="NOB46_001385"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCI1058327.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            8554..10257
                     /locus_tag="NOB46_001386"
     CDS             8554..10257
                     /locus_tag="NOB46_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1058328.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            10259..12292
                     /locus_tag="NOB46_001387"
     CDS             10259..12292
                     /locus_tag="NOB46_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI1058329.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            12303..12743
                     /locus_tag="NOB46_001388"
     CDS             12303..12743
                     /locus_tag="NOB46_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1058330.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(12943..14070)
                     /locus_tag="NOB46_001389"
     CDS             complement(12943..14070)
                     /locus_tag="NOB46_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058331.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(14073..14750)
                     /locus_tag="NOB46_001390"
     CDS             complement(14073..14750)
                     /locus_tag="NOB46_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058332.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            15014..16780
                     /locus_tag="NOB46_001391"
     CDS             15014..16780
                     /locus_tag="NOB46_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCI1058333.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            16795..17232
                     /locus_tag="NOB46_001392"
     CDS             16795..17232
                     /locus_tag="NOB46_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1058334.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            17245..18396
                     /locus_tag="NOB46_001393"
     CDS             17245..18396
                     /locus_tag="NOB46_001393"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCI1058335.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(18458..19156)
                     /locus_tag="NOB46_001394"
     CDS             complement(18458..19156)
                     /locus_tag="NOB46_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HCI1058336.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(19149..20501)
                     /locus_tag="NOB46_001395"
     CDS             complement(19149..20501)
                     /locus_tag="NOB46_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HCI1058337.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(20724..22124)
                     /locus_tag="NOB46_001396"
     CDS             complement(20724..22124)
                     /locus_tag="NOB46_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HCI1058338.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            22315..23022
                     /locus_tag="NOB46_001397"
     CDS             22315..23022
                     /locus_tag="NOB46_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HCI1058339.1"
                     /translation="MKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCCAPCSTHTLEF
                     MSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIVDEYRPNEFTK
                     MVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISPKKNAALINQI
                     GMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAKQQGCDLKEIN
                     REAKAYLKTSTVVFEEN"
     gene            23147..23626
                     /locus_tag="NOB46_001398"
     CDS             23147..23626
                     /locus_tag="NOB46_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HCI1058340.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            23623..24390
                     /locus_tag="NOB46_001399"
     CDS             23623..24390
                     /locus_tag="NOB46_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058341.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            24620..25189
                     /gene="lepB"
                     /locus_tag="NOB46_001400"
     CDS             24620..25189
                     /gene="lepB"
                     /locus_tag="NOB46_001400"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI1058342.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(25293..25895)
                     /locus_tag="NOB46_001401"
     CDS             complement(25293..25895)
                     /locus_tag="NOB46_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI1058343.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26001..26470
                     /locus_tag="NOB46_001402"
                     /pseudo
     CDS             26001..26470
                     /locus_tag="NOB46_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            26576..27160
                     /locus_tag="NOB46_001403"
     CDS             26576..27160
                     /locus_tag="NOB46_001403"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCI1058344.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            27163..28236
                     /gene="prfA"
                     /locus_tag="NOB46_001404"
     CDS             27163..28236
                     /gene="prfA"
                     /locus_tag="NOB46_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCI1058345.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            28229..29068
                     /gene="prmC"
                     /locus_tag="NOB46_001405"
     CDS             28229..29068
                     /gene="prmC"
                     /locus_tag="NOB46_001405"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCI1058346.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            29061..29240
                     /locus_tag="NOB46_001406"
     CDS             29061..29240
                     /locus_tag="NOB46_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058347.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            29262..30287
                     /locus_tag="NOB46_001407"
     CDS             29262..30287
                     /locus_tag="NOB46_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCI1058348.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            30462..31706
                     /locus_tag="NOB46_001408"
     CDS             30462..31706
                     /locus_tag="NOB46_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCI1058349.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            31859..32806
                     /locus_tag="NOB46_001409"
     CDS             31859..32806
                     /locus_tag="NOB46_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1058350.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            32940..33569
                     /gene="upp"
                     /locus_tag="NOB46_001410"
     CDS             32940..33569
                     /gene="upp"
                     /locus_tag="NOB46_001410"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCI1058351.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(33708..33950)
                     /locus_tag="NOB46_001411"
     CDS             complement(33708..33950)
                     /locus_tag="NOB46_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058352.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            34071..34143
                     /locus_tag="NOB46_001412"
     tRNA            34071..34143
                     /locus_tag="NOB46_001412"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34104..34106,aa:Thr,seq:cgt)
     gene            complement(34262..34900)
                     /locus_tag="NOB46_001413"
     CDS             complement(34262..34900)
                     /locus_tag="NOB46_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI1058353.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(35023..35655)
                     /locus_tag="NOB46_001414"
     CDS             complement(35023..35655)
                     /locus_tag="NOB46_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI1058354.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            36006..36305
                     /locus_tag="NOB46_001415"
     CDS             36006..36305
                     /locus_tag="NOB46_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI1058355.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        12367 a         6405 c         7388 g        10376 t
ORIGIN      
        1 aataaagttt ctttggatct agatttttta attgtcttgg caagatagca gcggggatag
       61 aaagcgagtg gcttaagtgg ttttttgtgt aatctaaggt atttcttgta tctaaaacga
      121 tgctgtcagc atcgagaggc aatttattga agtcttggac actaattgat tgggccattt
      181 atctcatcct ttgtttagta tgtggctatt ttaatgggca actctcatta attcaaatgg
      241 aaggattcct cttatcactt ttttaatgta tcggatgata atgaaaaaaa ctatgcaaat
      301 gtcttgcaaa acaggtagga ggtgttataa tgacatagcg tcatatgaca atgtgtcatc
      361 ttgaaagaaa ggagaatcca tatgccgaca cagacatttt tccatttgcc taaagaaaaa
      421 caaaaaagac taatcgaggc tgcgagaatc gagttttcta gagtaccctt aaaagaagct
      481 tcgattgcta atatcgtcaa attagcggat atccctagag gcagtttcta tcagtatttt
      541 gaagataaag aggatcttta tttttattac tttgagacaa tgagacgtga cagctctaaa
      601 gatatgttac aactaatgaa agaatccgat ggtgatctat tcaaaggatt cgaatcctat
      661 ttttctaaaa tgatttatga gattttggaa ggcgagaatg cttcttttta tcgtaacttg
      721 tttatgaaca tggattaccg tgcctcaaga aaagtcgctc ctcatacgag tcgccaaaaa
      781 acgcctcacg atccacataa agaacacaaa caagatgcaa aagagttgct tgaattgatc
      841 gatcggacga agctgaaagt aaaaaatgat catgaattgg aattactgat ccaattagtg
      901 atgaatactg tatttacaac aattgcgcat tcgtatcgct tattttcaac atctgaagat
      961 tactcagtag agcaagcaat cagtgaattc aatttgaaac tttcttggct gaaaaacgga
     1021 gtatataaat agaaagaagg gaactagatg ctaaaaatcg taaaacggat ctccttgact
     1081 tcagcaattg cagctgcagt tttcatggtg atccaagtac tggcagattt atatttgccg
     1141 acacttacct ccaatattat tgataaaggg gtagcgcaag gagatgtcga ttatatttgg
     1201 catacaggtt ttgtgatgat cggcttttct ttgatcagta tcttagctgc tatcgcaaat
     1261 acattttttg ctactcgtga atcacagaaa ctgggtaagc aattgcgtac ggatgtctat
     1321 aaaaaatcag agagtctgac aaaagatgcg tttgataaat atggaacggc ctctttgatc
     1381 acaagaacga ccaatgatgt gactcaaatc caaatggtta cacaaatgtt tttacgtatg
     1441 atgatcaatg caccaatcac gttgattggc gcgagcatac ttgcttatca aaaagatcat
     1501 cagttgacaa aaatcttctt agttgtcatc ccagtaatga ttattttgat cggcggaatc
     1561 atgtactttg ctgttccatt attcaaaagt atgcaaaaga aaactgaccg tttaaacctg
     1621 gtatttcgag aaggattgac aggggtcaga gtgattcgag cattcgataa gacacgcttt
     1681 gaagaaaatc gttttgattt agcgaataaa gattatacaa atacggcaat caaagttaat
     1741 acgatcgtcg cattgatgat gccaatgatg acattgatca tgagcggtac aaacgtagca
     1801 atcacttggt ttggtggaca ctacatagca gatatgactt tggaagtcgg taatctgatt
     1861 gcatttatga cttatgcgat gcagatcttg atcagcttta tgatgctttc cgctattttt
     1921 atcatggtgc ctcgtgcaca agcttcagct gaccgtatta atgaagtgtt ggatgaaaaa
     1981 atcggtatcc atgaccctga aaatcctaaa acagtttctt ttgctggaaa aaacgcaaca
     2041 ttggccttca atcatgtcaa ttatcgatat catggagcag aaaaacttgc attggaagat
     2101 attgatttcc aagccaagtc gggcgagatc gtcgcaatca taggggggac tggttcaggt
     2161 aaaacgacct tagtcaattt gatccctcga ttatatgaca tcgaatctgg ttcgatccaa
     2221 ataaatggaa cggacattag tgacatgact caatataatt tgcgagaatt aatgggcttt
     2281 gttcctcaaa aagcagttct gttctctgga acgatccgag acaatatgca gtatggtaag
     2341 ccggatgcaa cagatgaaat gatttggaaa gcattagaaa tcgcacaagc taaagatttt
     2401 gtttcagaga tggaagatgg cttagatagc catgtggaac aaggaggagg aaacttctct
     2461 ggtggacaaa gacagcgtct ggcaattgca cgggcattag tcaaaacagc agatatctat
     2521 gtgtttgatg attccttctc agcgttggat ttcaaaacgg atgccaatct tcgccaagca
     2581 ttgaaaacga atatgaaaga aagtatcacc gttttagttg ctcaacgagt aagtacagta
     2641 atggatgcag atatgatcct tgtgctagat gaaggaaaac tggttggcaa aggaacacat
     2701 gaagaactat tagcaacaaa cgaaacttat caagaaatcg ttcattcaca actaagagag
     2761 gaggacttag catgagtaaa acaaacacac gtccctctca tggaccagca ggcggtccag
     2821 gacatggtgg acctggcaga aatctcggtg taaaaggtga aaagcctaaa aatttctggg
     2881 gaacggtacg ccgattgttt ggctatatgt ctaaacgtat ggttgcgatc atcgctgtat
     2941 ttgtactagc aatagcagcc gtgatcttcc aaatccaaac accaaaggtc ttggggaaag
     3001 caaccacaga aatattcaaa ggtgtaatgg ctggcgctca acagatgcaa caaggccaac
     3061 aagtaacaaa atttccgata gactttgata aaatcgcgca gatcattgcg acagtaatcg
     3121 tgatgtattt gatttctgct gtattcaact ttttacagca atttattatg acacgtgttt
     3181 cccaacgaac agtttatgaa ttacgtcatg atttggaagc caaaatgaat cgtgtaccga
     3241 tttcctatta tgatacacat acaaatgggg atatcatgtc tcgagcaatc aatgatatgg
     3301 ataacatcgc aagcacgctg cagcaaaatt tgactcaatt tgtaactagt gcagtcacat
     3361 tgattggggt catcgtgatg atgctttcaa tcagctggca attgacgtta gtcgcgttat
     3421 tgatgatccc tttaagcttg atcatcgtga tgatcgtagc gccgaaatca caagtgtttt
     3481 tcgcagatca gcaaaaaagt ttaggtttat tgaataacca agtagaagaa acatatggtg
     3541 gtcataccat tgttaaaaca ttcaatcata ctgaaaaaga ccaggaagta tttgaaaaag
     3601 aaaatcagaa tctgtatgcc gctggttgga aagctcaatt tatttcggca atcatcatgc
     3661 cgttgatgaa tttcgttaaa aatctaggct atgtgttcgt cgctgtacta ggcggagtaa
     3721 aagttgcaaa tgggaacatg acattagggg atgttcaagc gttcttgcaa tatacaacac
     3781 agttctctca accaatcact caacttgcaa gtttgatgaa cactatccaa tcaacagttg
     3841 cttcagccga acgggtattt gaagtgttgg atgaagaaga gatgtccaat gaaaaatctg
     3901 gccttccaga agaaaaagat acaccataca aagttcgttt tgaaaatgtt caattcggct
     3961 acacaccaga taacttgcta atgactgatt ttaacttgga tgtcaaacct ggtgagatgg
     4021 tcgctattgt aggtccgact ggtgcaggga agacgacact gatcaacctt cttgaacggt
     4081 tctacgatgt ttctggaggt agtattcgtt acgatggtgt agatacccgt gatctttcac
     4141 gtgatgaatt gcgcgcacag ttttcaatgg tactgcaaga tacttggctg tttacaggaa
     4201 gtatctatga caatatcaaa tatgggaacg acgatgcaac agacgaacaa atcattgagg
     4261 ctgctaaagc tgctcacgta gacgattttg ttcgtaaatt gccagaagga tataacactg
     4321 tattaaacga ggatgcaagc aatatttcgc aagggcagcg tcagctaatc acaattgcgc
     4381 gggcattctt agcaaatcca gatgtcctga tccttgatga agcaacatct agtgtagata
     4441 cacgaacaga aatactgatt caaaaagcga tgaaccgcct attggaaaac cggacaagtt
     4501 tcgttgttgc tcaccgcttg tctacaatac gcgatgcaga caacattatt gtgatgaatc
     4561 atggttcgat cgtagaaaca ggaaaccacg atacattgat ggaaaaagac ggattctatg
     4621 cagatcttta taacagtcag ttttctgaag aagaagcttc atagaatagt acaaatttat
     4681 tatttttttt aggggctgtg acaaaagtcg tgtcacagtc cctttttccg aataaacggt
     4741 gttcaatcag ctgtccttcg gtattagctc aaaaaacggc aaaatatgag aagctatttt
     4801 tccgttttgt atctctaata ctcaggtcaa accgctgatt ttacaacctc ttccttaaac
     4861 ggtgttctcc tgccaactcc tcggtcacaa gtcacaatag tcaacaaacc tgagaagctg
     4921 ttttttgaaa ttgctccttg tgactcggag ttaaacggca ggctcacaac ctcttggtaa
     4981 acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa tgtagaaagc
     5041 cattttcaca aaatttttct tactactcga aactaagcga ctttttcaca acctcttcct
     5101 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaataggag
     5161 gagctatttt tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct
     5221 ttttataaga gtttttactc attaatttac aaaaaacaag caaaatgcga attttctcac
     5281 atttttttta acaaaatcaa agttattgct tgaaagaaga agaatccatc gttaaaataa
     5341 agcttgacgt agaggggagc aagaaatatg aaagattttc aattgggggc tgccacctat
     5401 ttaaaaagtg tagccattcg ggtgaaagac cgagataaaa tgattgattt ttacaagaac
     5461 gttgttggct ttgatttgaa aagagaagaa aacgaattag ccattttagg aacagaagaa
     5521 gctggaagtg aaatgttgct gctggaagaa agtcctagag cgaatgatca catgggggtg
     5581 atcaaaaagc tgaaccgttt ttcattgatt atccctagca cagaagaaat ggcagatatc
     5641 ctttgtcgta tccgtaaaat gaattatcca atcaaagaag ctttagaaga tcatggacgt
     5701 atggggattt tgctcgtaga cccagaagag aatgaattgg aaatttacca tgaagagaat
     5761 aagaacgacc aaagagaaat tccagaaaca atggatcaag aagcattatt aagaaaatct
     5821 gaagaaaaat tcagtaaact atcaacaggt tcttattttg aaaaaatcca tttaaatgtt
     5881 actaacttaa caaaagaacg ccaatttctt aatcatgtac ttggtttgaa ggtacataat
     5941 gaagaagagg gcatccatgt attgaatgaa ggagatttcc atgttggttt gacagaagct
     6001 agcggaggcg caattgattt gcctacagat gaagtgattg gacttgattt tctgaaattc
     6061 atgatcgata ctgaaagcat ggaaggactg attgctcact tgcagcaact atcagttgat
     6121 ttcttcttag acaaaaagca cacagtactc acaatctatg atgctatagg aatcgaatgg
     6181 tggttcgtca gtgagccaaa agaaaagaat aaaactgaca ttcgatgcga cgcttaactt
     6241 tttctttctt aacgattgtc gcatgtctcg tcattttatg aacggtcata ctatcgctta
     6301 ttctagagat agaaagagaa aatagtatac cgggggaaac tgcgcggttt ttcgcgcagt
     6361 ttttttgtgt aaaaaaggtt gattcctcat agattaagct ttaagcttgg actgtaagaa
     6421 tctgatagaa aagcaggaga aaaagatgta tccacacacg aaacagctta ttttgaaaaa
     6481 gatggaagaa ggattttatc caggtgtagc agtcgccttc ataaaagaaa atcaagtaga
     6541 aacatttaca gccggctttg cccaagtcgt tcctgaaaag cagctgatga cagaagatct
     6601 gttgtttgat gcagcctcac tgacgaaagt cgttgcaacc acttcattag ttttacgtct
     6661 attagaagat ggaaagatag aactcgatca accgcttcat aaatatcttc ctgaatttga
     6721 aaatcagaca atcactttgc gtcatttact gacacatact tctgatatca aaacatggat
     6781 accaaacaga gataagctat ctcaggaaga attgatcgcc gcttatttga agctagaacc
     6841 aggtgagcaa ctaggaaaag aagtaaaata tacagatgcc ggtacgattc ttcttgggtt
     6901 gatgctagag gaaatttacc aagaaactgc agtggaaatc tttcaagaac aagtattgga
     6961 accattagga atgatgaaca gcttatttct tccttttcct tccaaaaaaa tcgttcccac
     7021 agaacaactg ccttcgggtg aggttttgcg tggacaaact catgatccga aagcaagagt
     7081 tttggctgaa catgcaggta acgcgggtct ctttattgat ttgaaagaca gcattacttt
     7141 tgtccaaatg tatttgaaca agggaaaaat ccgtaatggt cgttttttag aagaagagac
     7201 gattgattct ttactgcaag atcaaacacc gaaaaaaaat ggctatcgtt ctttaggatg
     7261 ggacttaaaa aaggatgtag aagacggtca tgcgattctt tttcatactg gttatacagg
     7321 tacgtttttc ttgattgata taaaaacaca agaagcgttg atatttttgt caaatcgcgt
     7381 acatcctgtc gatcatcgtg cggagtatct catatgtcga gatgaaattg ttgaaaactt
     7441 tttgaaagag aaagcggtat taccgaaata atgctataat agctatgaaa aatgagagga
     7501 gtttgaatta tgcaggaacc tatgttttta aaaccagttt ttcaagaaaa aatttgggga
     7561 ggaagtcgtt tacgttcagt ctttggtttt gatatcccta acgataaaat cggagaagat
     7621 tgggcgatca gtgcgcatcc tcatggtgtc agtgtagtag aaaatggcga attcaaaggg
     7681 aaaagattag atgaactatg gtcagaacac aaggaattgt ttggccatcc ttcagaacca
     7741 gtgtttccat tattgatcaa gatcttagac gcagaagatg atctatctgt acaagtacat
     7801 ccagatgatg cctatgggat gaaacatgaa ggtgaattag gaaaaactga atgctggtat
     7861 atcatcgatg ctgaacctgg tgcagaaatc atctatggtc atcatgcaaa gacaagagaa
     7921 gaactagctg agatgatcaa agatgggcgc tgggatgacc ttttgaagaa agtaccagtt
     7981 aaaaaaggtg atttctttta tgtaccaagc ggaacgatcc atgctattgg taaaggaatc
     8041 atgattttag aaacacagca aagttctgac acgacttacc gcgtgtatga ctacgacaga
     8101 aaagatgcgc aaggacaaac aagagagctg catatccaac aatcgatcga tgtaacaact
     8161 gtccctgcga aaacaccaga attacaaatc aaagaagtcc gaaaagggaa ttcatcgatc
     8221 gtcacttatt tagaaactga gtttttcaat gtatatgagt gggatattaa aggaatcaca
     8281 tctttcaaaa aacaagcccc ttatacattg atgacggtaa tcgaaggagc aggagacctt
     8341 gtcgttgacg gaaaaacata tccattagaa aaaggaacaa gctgtattat tccaaatggc
     8401 gtttctgagt gggcggtcca aggtgaacta gcaatcattg cgtctgaacc aggcaaatag
     8461 ttcccagata gctgaaagca gcagacggtt tttcgtttgc tgctttttct acataaaatc
     8521 cgtccatcaa taaatagaag tctggtgaaa aagatggaat acaaatggaa agcaaacaac
     8581 agcagtcgcg tgtctatgaa acaactgaga aaagctggac atcacttaaa tgaaatgatc
     8641 atgccaaatc taagtctgtt tatcgcttgg ggaatcttgt cattagcaac aaaaggtgtg
     8701 tctggcgatt tgcataccac attagaagag gtatgccatt ggatgatcca gctgctttta
     8761 cccatcttga tcagttattc aggcgggaaa tcggtagggg gacaaaaagg ggcagtcgcc
     8821 ggtgcaattg cttctttagg gttgatcgct cgttccaatg ctccacaaat cgtaggagcg
     8881 atgattatcg ggccgcttgc cggcatcgta tatgaacaat ttgtttctag attccatgtg
     8941 aaattcaagg ctggatatga aatgcttgtc agcaacctac tagtaggact gactggtagc
     9001 gttatttgta taattggaat cgtttttatt gaaccagttt taaatagtgt tcacttgttg
     9061 ctcgcctccg ttgtgtcttg gctagtcaca atgaatctgt taccacttgt cagtctgatc
     9121 ttagaacctc taaaagtact atttttcaat aatgcaatca atcatggtgt attgacacct
     9181 ttaggaatcg aattctcaca aacagtcggg tactcttcct tatttttgat ggaggcaaat
     9241 cctggacctg gtttagggat cttactttct atcctttgtt ttgcagaaaa acaggaaaaa
     9301 gtaaatgcga gtggagcatt gatgatccat gcgattggcg ggattcacga aatctatttt
     9361 ccatttgtct tgctgcgacc gtatctattt ttagctgtaa tggctggtgg ggcaagcggc
     9421 acgttgatat ttcaatggtt agatacggga ttagctgcac ctgtatcgcc tgggtcacta
     9481 ctcgtgattt ttgccaatgc gccttatcca caactagctg gggtaagtat agggatagca
     9541 atcagtacat ttgtgacctt catttgtgca gcgatactat tgaaattacc aaataaagaa
     9601 aaagagaaca aaacggtcaa agaaagggga gaaatcttgg aaccatctat cattcattcc
     9661 gtcatttttg cttgcgactc aggtatggga tcaagtgcta tgggagccgc cctgctgaaa
     9721 aagaaattag cagcagaaaa aatcgatctt tctgtcggat acagctctat ctatgaattg
     9781 aataaccaag taaatcagct ggttatcgtg caacatgaac tagcgggtct tgcaagagaa
     9841 aaagtacctc aaagtcaaat ctatgtactg gatcactttt tggaaacaga tatcttgctg
     9901 tcacgaataa aagaagcgat ccaatttcca aagcgggaag aaaaaaaaga gatagcagat
     9961 atcacagaac aaaaaacgtc gcctgctaat attgtatttt tgtataaaaa caacagacgc
    10021 ggctcacaaa ctatgggcat gacgatttta agtcaattag caaaaaaagc gaaaaaacag
    10081 tttgttatct caaaagaatc aatagaaaaa atcaaaatcc aagaagaaac gatttatatc
    10141 gcacaaagag aactagctgt aactgaacag ctagaagaaa agatccctcg gctagttcta
    10201 gttgaacatt gggtagctac gaatgaatac gaaaaactcg tgaagggaga aatataagat
    10261 gtatttatcg cccagagaaa aacaattatt agcagaattt ctcagtagcc cgtcacctgt
    10321 atctatccaa aaaatgatga atttattgaa ggtcagtaaa cggactattt accgcgaatt
    10381 agataatctt gaagtctcat tgaaatcggt aaatgcttct ttgaaaaaag cagctagagg
    10441 ctcatttgtc attgaggcat cagaagaagt attagagcaa ttaaaagaaa atacagatgg
    10501 gaaaagtaat gacttatcca ctgctaaacg acaacacgcg attttagccg agttgttact
    10561 gacgacagag ccgttgagtc ttgctcattt catggaatca tatcgcatca gtaataccac
    10621 tttttatgca gatatcaaac agttggaaga aagtattcgc caactgcctt tggaaatcat
    10681 tcggaaccag ggatacgaga tcgaaggacc ggaaaaatac cgccggcttc tgacagcgaa
    10741 tgtattagaa ttagaaatca atgaatatga actttttcat agtatttctt tcgatgcatc
    10801 actgaattat ttttttcgat tcgttgatcc gcaacatcta tctcttgcac gcaaagtaat
    10861 cggggaagaa ttgatccaaa aaaagaccaa tctaagtgat agaaagcttg aacatttggt
    10921 tttgatgctg acattgacga tggagcgtgt gacgaaaaat catttactga caaatgagac
    10981 atataatagt ctggcaaaca aagaattact acagacagct aaacgattgt tttcacggat
    11041 cgcttctgag acaaaacaac tttatccagt aaatgagatc gtcttttttg caggattatt
    11101 aaatgacttc acgaactcat ttgatcagaa tttctttgaa gagacgttcg atacacagct
    11161 tgcttattta gtaaaacaac tgattcaaga agtaagtgaa gagacgaatg tccattttta
    11221 tgaagatgaa actttgtaca aaatgctgtt gactcattta tctggtgtgt tttcaagagc
    11281 cgttttacaa gaagagacac tgaccaatcc gattttagaa aaaatcatgg ttcaatacga
    11341 ggaagttgcg aatgcaatcc gtaaagcagt agagcggatt tttcaagaaa aaaaattatc
    11401 cgaagaagag atcgcttata tggtccttca ttttgcgaat tcattggaac gaagtccgaa
    11461 agaaagcaat atcagtattg caggattttc gccaagtgga ttagcttcta ctagcatgtt
    11521 ggaactacga ttgaaaaggt attttccctt catccaacaa attcatttct atcggattgc
    11581 tgatttaaaa aaaatcgatt tacaagaaga atatgatgtt gttatttcta catctatttt
    11641 accaggatac ggtggaaaat atattttagt ctccccgcta ctgctagaag atgaagtcaa
    11701 gcagctaaaa gaagcttttt cgcatattga gaagaaaaaa aggcaaaaaa ttacgtataa
    11761 cagcaataac gagtggatga tagaagatac ttatgaggaa acaatgcatt tcatggatca
    11821 aatcaatcaa ttactcggtc gtttttttat ccaagaactg gataatcctg agacgatttc
    11881 cgaaacgatt cgcagcttat ttccttattt tcctgaagga ctagtaacgg atgaagaggt
    11941 ggttcatcgc cggctgctta agcgatatga acaagcacct atcggtattc ctcatacaaa
    12001 tatggggtta ttccatacat ccagctcatt gatttctaaa ccgatctttt gtattttcaa
    12061 tttgaaacat ccgttgacca ttgaagggat ggatagacag ccagtcgatt tgtcccgtat
    12121 gttagttatg ctggcgcctt cgccaatcca agaaaaagac gggattcttt taggaaagat
    12181 cagtggagca atcatcatga atgacttgaa caccgagatc ttccgctcag gaaataaaga
    12241 aatcgtttat cagttgttag cgaaaatcct gattgaagaa ataaagaaat gaaggtgaaa
    12301 agatgataca gctaccagca gaaaaaatat tgctcgatca atcctatcaa aattggaaag
    12361 aagcgttgac cgagatcggc cagtggatga cccaacaagg gggaatcaaa ccggcatata
    12421 tccaatcaat gatcgaaaga caagaaaaag cgagtgtcta tatcgggaat ttcgtagcct
    12481 tgccacatgg gactgacaaa gatgaagaag tagtagaaga aggaatctat ttagtccaag
    12541 tgcctgatgg tgtggacttt ggaacaaaag aggaaccaaa aatcgcgaca ctcttatttg
    12601 tagtggcttt aaaaaaagaa catcagttag cggtgctcca agatttagcc tttttctgtt
    12661 cagacatcga ccaagtaatg gcgctcagtg atgcggaaac cattgaagaa gtccaaatga
    12721 tttttgaaca tggacatata taaccaatgt tcacagtaaa aaaagctgcc ttgcatcaag
    12781 taataacttc aaccaagata aaaataagag gagctatttt tgttgggagg ttcttattac
    12841 tgcggatgca agcttttgaa aactatttat tctagaaaac cgtttatttg aaatagggga
    12901 cggtgacaag gtttttgtca ccgcccctat tatttttgtg ttttaatagc tcttttttat
    12961 atagatagtg cccataccta tgaataataa aacgatactc catataccaa gtgtcaagat
    13021 accattcatg aaagtaacct gttctgaagc tagtggcgag aaaatatctc ctcctatgat
    13081 cacattttga aaatcaacat aagaagttgg caagtaatga ctgattgatt ctatccatcc
    13141 aatcgaagaa aacaagcgat actctgctaa gaaaagacaa agaagtgtac ctaaaagatt
    13201 gactagagaa tgttcaaata aagcagatag aagaaaactg attgtactta aaaagagcac
    13261 ccacaacaac aggaacagaa agctctggaa aagatactca tacatcggca ggattcgtat
    13321 ctcctgacca atgatcgttc ctacaggata acggaagtct cccaaaccat ttttgattat
    13381 tactagtata gagacgatca aaaatggcat cacgagactt agcatagctg caccataata
    13441 aatggtaaaa cggatgctat gtttctttac catactatcc ggtaatagat tgactagaga
    13501 gattacctgc tttctttttt cataagagat gatggaagaa agaaacaagg cggttataca
    13561 taaaatcaaa aaactagaaa tcattcctga aaaaatattt tcgtagtaat ttgctaaaga
    13621 gagatgcgct ggcaagtcaa aaatagaata tctttggatc tgatgttctt tcatataacg
    13681 gagcaactcg acacgttttt gttgttcaat gattggaatt ccttgtcttt gaccagaaat
    13741 cagtcgatcc agtatatctt tttcataatg ataagttgct tcgaccattt gctggacatt
    13801 ccctgtgttt tttgcatgta agattgcttc gatcagtttg ttgcttttct ctaaactttc
    13861 cacaaattct ttctcattct catcttcttt caacgtttca atcaaacgtt gcatctcttc
    13921 atagttatga ttcagttcat cgaattctgt ataagcaagt ttatgatcaa aaaaaagtgg
    13981 gaatgcaaag agcacgacca acaatagagg aaataaaaag tttactttgt tttttagtaa
    14041 gagattgcgt tcaaatgtaa gtaaagacat agttacacct catataattt acgataaata
    14101 gctaaaatct cttccatatt tgaggattct gtgacgattt ctccattttt tagaaaacat
    14161 gctttagaac aaatcgattg gatattcgcg atagcgtggg aagaaagaag aatcgtcttc
    14221 ccctctttct gccattgtct gatgaggcta ttcaagatat caatacttcc tgggtctaat
    14281 ccgttcaacg gttcatcgaa taacatgaca gatgaatcac tgatcaagta agcagcaagc
    14341 aagacatgtt gtttcattcc tagagacatt tttccaatcg gcaaagtaag gtactcagtc
    14401 atcttcaatc gttggaaaac agtttggcat tctactttgc tctgccaata gtatttgatc
    14461 aaagtcaaat aatcaacagc cgatagatag tcggataact gattcgttga ttctagaaaa
    14521 aagaaagacc ggcgataatc tgtataagca gtaggagaga tgttgtgaag ggacaattga
    14581 tcataagttg ttggcagcag ttgggcaatg ccattcagca aagttgtttt gccaaatccg
    14641 ttcggggcaa tcaaagcagc tacttctcct gattctacta aaagattcaa ttgtcgaatc
    14701 acacgttttt taccacgttt catgttcatg tttttgatca gtaatgtcat agataggcct
    14761 ccaatataaa atttaataac ataatagaat ggaaaacatc taaattaaat gctaacaaaa
    14821 gttattgttt gcatattata aaaaaattaa aataacagtt ttatttaaaa ttgaagtttt
    14881 ctgataccga aatcttttta ttttgctgac atactcaaac ctttggcaca aagtttcgtg
    14941 ccaaagtacg actatttctc tttttagtaa gcggatacaa ttagagtatc aaaaggagag
    15001 agggagagac aaaatggaac ggacgattcc caaaaacaac atttcgctaa aagcgagggt
    15061 acaaaaatta ggcagtactt tatcaagcat ggtcatgcca aatattggag cactgattgc
    15121 ctggggtgta ttaacggctc tatttatccc agatggttat ttaccaaatg aggctttcgc
    15181 taccatggta agcccaatgc taacttatct gattccttta ttgatcggtt atactggcgg
    15241 aaaagtaatt gctggtgacc gcggatcagt tgttggggca attgcaacga tgggtgtgat
    15301 tgtcggaaca gatattccaa tgatgctagg cgcgatgatc atgggacctc ttggtggata
    15361 tgccatcaag aaatttgatc agctattcca aaaacggatc aaatccggtt ttgaaatgct
    15421 agtcaataat ttttcagcag gtcttatcgg ttttggatta gcgttattag gtttttctgc
    15481 gattggtcca gttgtcgatg cattgactca agcaatggca aaaggtgtag agatcatttt
    15541 atctgcccat ttgattccat tgacaagtat ttttattgaa ccagcaaaaa tcttattttt
    15601 gaataatgca atcaatcatg ggattttgac accattggga actgaacaag tagcagaggc
    15661 tggaaaatct attctattct tgcttgaagc aaatcctggt ccaggacttg gcgtattact
    15721 tgcttttact ttgtttggca aaggagcagc aaaatcttca gcaccaggag ccatgatcat
    15781 tcacttttta ggcgggatcc atgaaatcta ttttccttac gttatgatga aaccgttatt
    15841 attcttatca gttataggcg gaggaatgtc aggaagtttc attttccaat tgatggatgc
    15901 tggactaaga gcgccagctt ctccagggtc gatcattgcg attctagcga tgacaccgtt
    15961 caattcttac cttcctgtta ttttgggcgt gattgttgcc gcagctgttt cgtttggtat
    16021 ttctgcagta attttgaaag cggatgcgaa agatacaaat gaagacttcg aaaaatctgt
    16081 tcaagagaca aaggcagcta agcaagcttc caaaggtgcc caaggtattc ctcaaggagc
    16141 tacattctct ggcgtacaaa aaatcatttt tgcttgtgat gcaggaatgg gatcaagtgc
    16201 gatgggcgct tcgatcttga gaaaaaaagt acaggaagca gacttgcctc aaacggtgac
    16261 caatcaagca atcagccaac tgacagatga ctcgaataca ttgatcgtta ctcaggtcga
    16321 actacaagaa agagcaaaac aaaaagcacc gagcgcgcgt tttgtctcag tagaaaactt
    16381 tttgaattca cctcgatatg atgaaatcat tcaagaatta agcagcaagc agaaaacatc
    16441 agtttctgaa attgagaatg agccagcaga agagtttctt tcagcaaaca tcaaacaaat
    16501 caaagagatt ctacttgtcc acgatgatcg ttccggatca gcaacaatgg ggatgaccgt
    16561 gctcaaagat atattagaca agaaccattt aactatcccg ttaagaaaag tcaatatcca
    16621 agatttaaaa gatgaacctg attcactgat cgtagccaaa gaaagtttag cggaaaaagt
    16681 acagatggct gcacctcaat ccattcattt atcagtcaac agcatggtca atccgcaaaa
    16741 atacgaatcg attgcacaat atttgaaaca gacagcttaa gggaggaaaa cagcatgcaa
    16801 agtttgccat tcgacatgat cgagctcaat cgatctttta aaaccaaaga agaagcgatc
    16861 cgctattgcg gtcagatgct tgtagaagca gggtgcgttg atgaggaata tatcgatgcc
    16921 atggtagata gagacaaaat gttatctgtt tatatgggga attttatcgc gattcctcat
    16981 ggaacagatg aagcaaaaaa atatgtgaaa aaatccggca tctgtgtcgt tcaagtacca
    17041 gatggtgtag attttggtac cgaagaagaa gaaaagattg cgactgtttt gttcggtatt
    17101 gcaggagtcg gagatgagca tttgcaactt gtacagcaaa tcgcacttta ttgcagtgat
    17161 atggacaatg ttgtccagct agcagacgcg ctcagcaaag aagaagtaac ggaaaatcta
    17221 gcaattgctt aaggagagag aaaaatgaga gcagtacatt ttggtgcagg aaatatcggt
    17281 cgaggattta ttggagaggt tttggcagct aatggatttg agattacttt cgtagatgtg
    17341 aatcacacga tcattgatgc tttaaatgaa agaaaagaat acgaaatcga attagcagat
    17401 gaatcaaaag aaaaaatcac tgtaaaaaat gtcaaaggaa tcaacaatca aacaaatcca
    17461 gaaaaagtaa tccaagaaat cgctgaagca gatttagtta ctaccgccat tggcccgaat
    17521 atcttacctt ttattgctga gttgattgca aaaggtatcc aagaaagaga aaaggaagga
    17581 agcacaacat ctttagatat cattgcctgt gaaaatatga ttggcggttc agcatttcta
    17641 gaaaaagaag tgtataaata tcttccggaa acatcattta ctgacaaata tatcggcttt
    17701 ccaaatgcag cagtcgatcg aatcgtccca ttacaacacc atgaagatcc tttattcgtc
    17761 caagtggaac ctttcaaaga atgggtcatt gacgatagcc aaagaaaaaa taaaaaaatc
    17821 caattaaaag gggttttata tgtagatgat ctagaaccat atatcgaacg caaactattt
    17881 agtgtcaata ctggtcatgc gactgtcgct tatacaggtg ccttgttagg ttaccagacc
    17941 attgatgaag caatgcaaga tgcgttagtt gtggcacaat taaaatcagt tttgcaggaa
    18001 acaggaagtt tgctgattgc caaatggggg tttgatgcag agcagcatca tgcgtatatt
    18061 gaaaaaatca ttcatcgctt ccaaaacaaa aatatctctg atgcgatcac acgtgtcgct
    18121 cggacaccat tacgtaagtt aggttatcaa gaaagattta cacgtccagt gagagaacta
    18181 caagaacata acttgacttg cccacatttg acggcaacaa tggggattat ttttaattac
    18241 tatgatcctg aagatgaaca aagccgtcaa ttgcatgaaa tgaagatcca tgaaaacttg
    18301 gaacaattga ttcaagaagt cacaggaatc aatgatccga aaacaatcgg gaatatcaag
    18361 caaaacgtga accgttatgc caagcaagtc gcttaaaata ggatacgaaa aaggggaatg
    18421 tgacgaaatt tttgtcacat tccccttttt cgaataacta ggctgtttgt ccttcaagat
    18481 agggcagatc caattcttta ccgtaacgtt gttctaaagc taggcggatc aaacgagctg
    18541 ccaggttctc atttcttgca aggataggtc catggaaata agaaccgaag acatttcggt
    18601 aaatgacacc ttcagattgg tcttcaccat tatttccttg accttgtacc actttcccca
    18661 aaggtcgttc accttcacct aagaaagtcc gaccattgtg gttttcaaat ccataataag
    18721 tttcattgaa ttcttcgtta tggataacga tatcaccgat aaaccggtta ttttcctgac
    18781 ttaacgtgta gtgatccagt gcactgattc cttggatctt ttctccatta gctcccatgt
    18841 agtagtgacc tagcaattgg tagccaccac aaatggctaa catgacgcca tcattttcga
    18901 tatagttgat caaagaatct ttctttttct ggatgtcttt tgaaatgatt aattgctcaa
    18961 agtcttgacc accgccaaag aaaaccaagt catatttatc agcatcaaaa ggttcatgta
    19021 tactaacgat ctccgtatgg caagaaaccc ccattttttc tgctatatat ttcaacatca
    19081 aaaggtttcc gttatcacca tatgtgttca tcaaatttcc ataaaggtgg gcgatattga
    19141 gttcataatt agccacggtt cattcctcct ttgataaatc cttgagcagc tagttcttta
    19201 cgaagctgca atacagcagt gtaagtagct aaaatataga catgctcagt tggcaattct
    19261 ttgatttttt cgattacttc tggtaattct tttgtttctg tcaatttatt ttctggaatc
    19321 ccggcaactt ttagacgtaa agtcatatct gtatgacggt ctcctccaga aataacagct
    19381 gggatatcca tatcggcaaa gttttcaaaa ttaccatccc aaatccagct gacatcgatt
    19441 ccgtctgcgt aattggcatt taataaagcc actaaagaaa atggataagg agctagacca
    19501 atcatatcga ttacttgatt gatacctaca ggatttttga caagtactaa tgtacatttt
    19561 ttcccattga tattgatgac ttcttgtcgg ccgaatactt tctcgtcata tcctaaacct
    19621 tgtttgattt tatcaggatc gacattgaag tactctgcca ctgcagtagc tgctaaagca
    19681 ttgtagacat tatacatacc gccaacttcg attccgtatt catgaccatc gatcacgaaa
    19741 tctgctgaca cattgtccat ccgtaccata tcagttaatc gataatccaa ttcaggacgt
    19801 ttgaagtcac aatttggaca gtaatatttc cctaagtttg cataagtgat cattttataa
    19861 tgcaagatgt gatgacaatt tggacataag acaccgtctg tattgtaatg agccatttgt
    19921 tcacgatctt cttcatggtc aaagccataa tattttctag gattgactgt ttcgatagaa
    19981 ttgaagattg gtgaatcacc gttactgata atcgttgcat ttggtgactt tgcggcaccg
    20041 tctacaatca ttttataggt cgtatagatt tctccatacc gatccatttg atcacggaaa
    20101 atatttgtaa ataagaacag ttctggtttc atatattctg tgactttgct caaacttgct
    20161 tcatctattt ctaggacagc aaactttttc tgtccttttt ttggttttgc ctgcaagaaa
    20221 gtcgatacaa ttccctgtac catattcgca ccagtagggt tggttagaac ttcatcgaat
    20281 tgctggcgca aaatattgac tgttaaagcg gtagtcaatg ttttaccgtt tgttccggtg
    20341 acaacgacga cttggtagtc ttttgccaaa ctatctagta tatgtggatc gactttcagc
    20401 gctagtttac ctggtaaact tgatccgcct ttaaaaaaag tttttaatgc ccattgcgac
    20461 gtttttccaa ctgcaatcgc aaaatgactg cgtattccca ttatgtaacc tccaaaaacg
    20521 atttgctgac gaataaattc aactaatcat accatatgtt gaaaaaaagg ttaaattgct
    20581 tttcttattc ttaagaaaag gttacggctg aaagtgcatg aaatcggaca aaatcgcatg
    20641 atttaacaaa aaaacagctt gaaacaaaat gattgtttca agctgctgtg attttattat
    20701 tccctcttac ctatattccc attttaaccg ataataattt tctcgcttgg atattcatag
    20761 cctagatctc gtgtttcttt tggcacgaat aacatcaatg tatatagcat tccgatccgc
    20821 ccaataaaca tcagtgtagc aatcgtgatt ttgcccacaa cagacaagtc tccggtaatc
    20881 cctaaagata aaccagttgt tccaaacgca gaagttactt cgatgatgat cgagatcagc
    20941 gtttgttctt ctgtagcaga taaaaaaacg atacaaaaga aacacatacc aagagaaagc
    21001 ataaagacaa cgactgattt tcgcacatca tcttgatcga ttctccgtcc aaaaatattg
    21061 atgttatctt cacttttgag gaaggaatat agatacaaac cgatgattgc tacagtagtt
    21121 gttcgaatcc cgccgcctac agaactagga ctgcatccga taaacatcag taaagaaaaa
    21181 atgatcagtg ttgtgatttg aaaatcaccc aaatcgtgaa tctgcagacc agcattacga
    21241 gtcgtaatcg aataaaacat cgaattgatc catttgacac tcatattgga atcttggaat
    21301 aaatggtcct tttccaatag ataaatcaag acagttcccg aaacaaacaa gataacaaaa
    21361 gctaacacag ctaatttggt aaacaaggaa aaacgaaacg gaagcttcgc attggaacgt
    21421 ttgtataata gccattcccg gcactccatc aatacaggaa aaccaattcc tccgacaaaa
    21481 atcaaaaaca tgatcaggat caagaaaaaa tagtcatgtg caaagggctt gatggaatcc
    21541 ccagtgacgt caaacccaga gttcgtgaca gccgatatcg cctgataaaa accgtaaaaa
    21601 acggcatcac gccaacgatc aaaatagcct ctgtaataaa aataaataga aaagaatgtc
    21661 ccaaaaagta attgaaacca gattaaaata gcaaaagtga tccgaatcag tcggacgata
    21721 ccagacaaac gcggttgatt catatccgtc atgatcagct gtcgctgttt cagtgtgatc
    21781 cgtcgtttag aaaaaatgac aaaagcagta gaaatcatca tgatccccaa accaccaact
    21841 tgaaataata tttccagcag tataataccg ttatcattga acacagaatt gatatcaaaa
    21901 gtcgatagtc cagtcacact cactgtactg attgccatga acagcatgtc cacaaaagaa
    21961 acatggctat ctggttcgcg aaaaatcggc atataaaata gaacgagtga taagaccgtc
    22021 atcaatatat aataaaaaac gatgatttgg atcgatgaga aatgattggc agcaaacttc
    22081 tgtcctcgcc gctgcagcct tcgaaagaat aaatcaacat gcacagtact atcctcctga
    22141 caatagtcgt ttctaccagt atacaagggg aattaggaat actcaaagaa attatcaaac
    22201 agataacaat acagctttcg attaaaatag aaatggctta taataaggaa aatcctagaa
    22261 aaaagaagga ggaggaataa caaattattt aatgctcaac aaatcgtaga aaaaatgaaa
    22321 aatcaaaaaa taaattatga tacagttctg aaaaaaatga tcatgcaatg ggagaaagaa
    22381 gaagtaaagc ctaagatatt aatacataca tgctgtgctc cttgcagtac acacacattg
    22441 gaattcatgt ctcaatatgc agagatcacg ttattttttt caaattcgaa tattcatcct
    22501 aaaagtgagt atttgcgaag attacatgaa caaaaacgat ttgtagacca atttaatgag
    22561 aaaactgacc atcatgttgc gctaatcgtt gatgaatacc gtccaaatga attcaccaaa
    22621 atggttttaa caaaccatct tgaaaacgaa aaagaaggtg gtgctcgctg cagtgcatgc
    22681 ttcaatatgc gattagatct tgttgcgcaa aaagcgcaag aactaggata cgattacttt
    22741 ggaagtgccc tgaccatctc gccaaagaaa aatgcagctt tgatcaatca gatcggaatg
    22801 gatatccaaa agatttacgg gacacaatac ttgccaagtg atttcaagaa aaacaaaggc
    22861 tatgaacgct ctttgcaaat gtgcaaagag tatgatattt atcgccaatg ttattgtggt
    22921 tgcgtgttcg ctgccaagca gcaaggatgc gatctgaaag aaatcaatcg ggaagcaaaa
    22981 gcttacttaa aaacatcaac cgtagttttt gaggaaaatt aaagaaatct ttcggaaaaa
    23041 cgtaagaaaa aaataaagaa tttatggtag aaataaggta gactgtataa tttgtccgta
    23101 gtaaagtaag gaaacaagaa taaatttcaa tgaaggaaga gataagatgc gaaaagtagc
    23161 acctattttg aagccaatcg ctgtattaac aatctcgacg attgtcgcga ctactacagg
    23221 tattgtgaat agttccagct accgtgcacc aagttcaagt tctagtactg tagaagaaac
    23281 aacaccaact acttcagtct cgacatctga accaacaaca acggaaagtt tgaatgaaac
    23341 cactacgaca agtacatggg acgatacaac aactagttcg tcgtatgatg agacatatac
    23401 aactgacagc tcaagcgaaa caagtaatac ggtaccagat ggcactccat cggattcaac
    23461 caatccaagt acaagtccgg atacaagtgc tagctccgaa acgataccaa gcagtacgac
    23521 tgtagatgat aacacgcaaa atgatgatgc agcacgtaca gcacagcaaa accaagattc
    23581 aggaaatacc caaacgtata accagcaagc aggtgattct caatgacatt tttactagac
    23641 cttatcaacg gggtgcataa attccttggc tatttagaca tcagtcctaa atatcttaac
    23701 cgtggatata cgattttaag tgtgattccc acgctttatt tattgagaat tgtttatgga
    23761 ctttggcaaa accaaaacta tcttcaattt ttcttatatg gacttgcatt tctagtgctt
    23821 gtttatttta ctgttttaaa tgtattttat tactttttag ataaaaacac gaaagccgat
    23881 gtcactcagc tttttgtgaa gtatttacct gatgaagcgt tcaacatcca gacagaagaa
    23941 tcgatagata atggaaattc gatcgataaa gtgaatacac aagaggtcat ggtttcttat
    24001 gacgaagatt atcaattgaa attagccgag aatatgcggt atttgattgg aaatggtgag
    24061 atcaaaacaa atgaactcgg tcgcatggat ggatttctgg tcgatagaaa tacattgtat
    24121 ccttattact atgtcaagaa aacaggagag aaagagtatg ttctaaatat tggacgaagc
    24181 tactcggaca tggaaaaagt agggaccatt cgacttgact caacagaaga cacattggaa
    24241 cctgtcggat tgttcatcgt cggcggtgat tttgtcaaag acgggttacg ctatcatgag
    24301 ccttatcgtc tgaaattgat tgcaaaaaag gcacagtcgc aggaagaacc agtggtttat
    24361 agtcgtagcc aaagaagaag acattcataa tgtgatgaaa cgccgtgtat cagtggttgc
    24421 gataaaaacg tttattcgga ataaggggga tgtgacacgt cttttgtcac gttccttttt
    24481 tatataacga gaaagataag acgaacacat cacttattct ttcctttcat ttataaacat
    24541 tgtagaataa agaaagtaca acgaagtatt gtgaaaaaac gtaataaata acgaggaaaa
    24601 tacaagtagg aggtaagctg tgaaagaatt tttgaaaaat tgggggattt tgatccttgt
    24661 attagcggct attttattag ctagagtgta cgtgtttaca ccagttactg taaacgggca
    24721 ttcgatggac cctacattaa gtgatggaca acgattgatt tcatctaaga tctcaaacta
    24781 tgaacgaatg gatattatta ctacaaagga accgggggat gaagaacgga tgattgttaa
    24841 acggatcatc ggtatgcctg gagatacagt caagatggaa aatgaccagt tgaccattaa
    24901 tggcaaaaag tatgatgaac cttatctgga tgagttcaaa aaagaatttt cagaagataa
    24961 gttacaagga gaatatgctt atagctcagg attccaagca caagcagaaa gttcatccac
    25021 ctttacgagt gactttgaat atactgtgcc aaaaggaaag tatcttgttc taggcgataa
    25081 ccgcttgatt tcaaaagaca gccgaatgtt tgggttagtc gacaaagata tgatccaagg
    25141 aaaagttgtt ttccgttatt ggcctctttc agaaattaaa atcatgtgat gaaaaaataa
    25201 aaagaagctg tgacatgttt tttgtcacag cttctttttc cgaaaattcc ttcttatttc
    25261 ttggagttgc tcactttttt tgcaatctca ttttaagctt tttggctgat ggataagaaa
    25321 agcgaagcgt ttttgttcat aaatagcttt tccccacgat ggaaggtatg actagtagca
    25381 gagacaaagc ccgttttttc caatcgatta ttcaattctt cttggctaaa gccattatgg
    25441 actttcggat gactaatttg ttcattcttg tcaaagtcta cgatgatcaa ttgaccgcca
    25501 ggagctaaaa tttcataaag ttttgtaaga atattctccg tatcaggaat gtgtaaaagt
    25561 acaagtgata gaaggatgag attagcttgg acagcaggaa attcgacaga agcatcagcg
    25621 tggatcgttc ggacattttt cagatctgct gcttggatct tttcttctgc cattttcagc
    25681 atagtttctg aagcatcggc aatgatcagt tctttgaatc tttccgcaag cggtaaacta
    25741 acaagcccag ttccgcctcc gtaatccagc aggacttttt ggtggctgtc gcgcggtaga
    25801 taagtagtta gttcttcgcg aataatcttg gctaatgctt gacggtcagg ggaatcataa
    25861 tggttagcga tggaatcaaa aatatttttt gtcatcaaat agctccttac gtaaaacttt
    25921 gaaattttaa cttattatag cacgtgaaaa gaaagaaagc atgctatact caattcaaaa
    25981 agggagaatc tagaaagaat atgccgatat cgtttgtaaa agatagagag gaaaaaggaa
    26041 agtgtgtccg agaaatatta ctagacttgc ctgagtggtt tgggcttcct gaatcaacgg
    26101 aaaaatatat cgaggaatca agtaaactac ctttatggtg tgaaaaaaga aaagaagaat
    26161 atttaggctt tatcactctt tcacagacaa gtgaagatac tgccgaaatc tattctattg
    26221 tatgggaata aaaaaagact atcatcacca aggattagga acaaaacttt ttaaagaagc
    26281 agaaggttac gcagcaaaac attacaaata tttgcaagtg aagactgtag acgaggggca
    26341 ctactctata tatgatcaaa ctatttgttt ctacgaatca ttaggatttt caaggttgga
    26401 agtttttcca aatttatggg atgaatggaa cccatgttta gttcttgtca aaaaattgga
    26461 acaaaagtga gcaatagatt taatactaat ctgtgcttga tgaaaattct cactgtaaaa
    26521 aatgctgaaa atcaagtata ataccatagg aacaaactgg aaggtgaaaa agagcatggc
    26581 acaactattt tttaagtatg gcgcaatgaa tagcggcaag acgatcgaga tcctaaaagt
    26641 cgcacataat tatgaagaac aaaataagcc agttgtctta atgacaagcg gtattgatac
    26701 aagagatggt ttaggcgttg tttcaagccg aatcggactg aaacgtaatg cgatgccgat
    26761 atttgaagaa acagacgtat ttgacgtaat tcagaaaatg gaaagcaaac cctattgtgt
    26821 gctgatcgat gaagcgcaat tcttaaaaaa gaaacatgtc attgctttta cgagaattgt
    26881 ggacgaattg gatattccgg ttatggcatt tggtttgaaa aatgattttc gaaacgagtt
    26941 atttgaagga tcaaaatatt tattgcttta tgcagacaaa atcgaagaaa tgaaaacaat
    27001 ctgttggttc tgccacaaaa aagcaatcat gaatttacat tatattgatg gaaaccctgt
    27061 ttatgaaggc gatcaagtgc aaattggcgg aaatgaagct tattaccccg tttgtcgaaa
    27121 acattacttt cacccatcaa tgattacaga aggagaataa gcatgtacga tcaattacaa
    27181 gcaattgaag accgttatga agagcttgga gaacttttaa gtgacccaga agtgatttct
    27241 gatacaaagc gttttatgca gctttcaaaa gaagaagcaa acacgcgcga aacagtcgaa
    27301 gtttatcgtc gttataaaga agtagtacaa ggaatcaccg atacagaaga actgcttggt
    27361 gaaaaactgg atgatgaaat ggctgaacta gcaaaagaag aattatctga attaaaaaaa
    27421 gaaaaagaag tcttagaaga aaaaatcaag atcttgcttt taccaaaaga tccaaatgac
    27481 gataaaaata tcatcatgga aatccgtgga gcagcaggcg gagacgaagc agcattattc
    27541 gctggcgatc ttttcaatat gtaccaaaag tatgctgaag cacaaggctg gaaaacagaa
    27601 gtgatggaag ctaacgttac cggaatcggt ggatataaag aagtgatcat gatgatcacc
    27661 ggagacaacg tatattcgaa attaaaatat gaaagtggtg cgcaccgcgt ccagcgtgtt
    27721 ccttcaactg aatcgcaagg gcgtatccat acttccaccg caacagttgt cgtgatgcca
    27781 gaagctgaag aagtagagat cgatattgaa gacaaagata tccgtacaga tatctatcat
    27841 gcttcaggtg ctggcggaca gcacgtcaat aaaacagcat ctgctgtacg tttgactcac
    27901 ttaccaacag ggatcgttgt tgctatgcaa gatgaacgtt ctcaaatcaa gaaccgtgaa
    27961 aaagcaatga aaatcttgcg tgctcgtgtg tacgataaga tccagcaaga agcacaaagc
    28021 gagtatgatg ccaatcgaaa atcagcagtc ggaactgggg atcgttcaga acggatccgg
    28081 acgtataatt tcccgcaaaa tcgtgtgact gatcatcgta tcggattaac tatccaaaaa
    28141 ttagatcaga ttttagcagg gaaattagat gagatcgttg atgcattgat catgtatgat
    28201 caaacatcaa aactggaagc tatgcaaaat gggtaaaatg acctatcgag aagtcctgtc
    28261 acgggcttct tcttttttag aggatcatgg gaaagaagca tatagtatcc aatttttatt
    28321 tttggaacga aaacaatgga aaaaacttga ttggctcctt catatgaacg aagagatttc
    28381 agaagaagaa cagcggttga tcgaaaccga tctgcgactt ctgcttgcag atcatccacc
    28441 tcagtatttg ctaggatatg cagattttta tgatcatcgg ttaaaggtaa ctgaagcaac
    28501 actgatccct cgaccagaaa cagaggagtt agtcgaatgg tgtttagacg agacgcctgg
    28561 tgtaccgtta gaagtgatag atattgggac agggactgga gcaattgcta ttagtttgaa
    28621 agcagcaaga aaaaattggc atatatctgc tgtggatctt tcagaagaag cattagaagt
    28681 agcgaaagaa aatgctcaga aagaaggaac gaaaatcagt ttttatcatg gagatacatt
    28741 aggaccagta atggatcagc aatttgatgt gattatttct aatccgccgt acatcagtcg
    28801 gaatgaatgg gaactgatgg atgaaagtgt ccggtcattc gaacctaaaa tggccctttt
    28861 tgctgagaac gatggattag ctatttatga aaaaatagca gttgaagcac caagcgtact
    28921 aaaatcaaat ggaaagattt ttttagaaat cggatttcgc caaggtgaag cagtaaaaaa
    28981 aatatttcag caagcatttc cagataaaaa agtggcgata aaaaaggatc tttttggcaa
    29041 tgaacgaatg atccaagttt atggttgaag ttgtggatga aaaatttttt atttgttttt
    29101 ttattataaa aaaacactta tttgacaagg atgtaaacga ctttttggtt tatcaacaag
    29161 tttatccact attgacaaat agattatcca caaacagtgg aaaacttgag gataaactca
    29221 gacaaaataa gaatgtatga aaaaggggtt gtggataaac tgtggaaacg aaacgatatg
    29281 atgaaacaga attgcaagag gcagccgaag cactgaaaga aggagaactt gttgcttttc
    29341 ctaccgaaac agtatacgga ttgggcgcca acgctctttt accaaacgct gtcaagaaag
    29401 tgttttctgt aaaagggaga ccgcaagata atccattaat cgtccatgtc gcctcttttg
    29461 aacaagtaaa agagtatgtg gacaactttc atccggcagc agagaagatt gtgaagaact
    29521 tctggcctgg accattaact ttgatattta agatcaaaaa agacactttg ccctcagttg
    29581 tgacgggagg attatccaca gctgcatttc gtataccgga taacaaaaaa acactagaag
    29641 taatcgaact ttccggtgtt ccgcttgtcg gtccaagtgc aaatacgtcg ggaaaaccaa
    29701 gtccaacgac tgcagatcat gtatatcatg atctacaagg aaaaattacc gggattattg
    29761 atgatggagc tacgcgaatt ggtgtagaat ccactgttct tgatttaagt gatccaacag
    29821 ccatgcctat gattttacga ccaggtgcag taacgaaaga acaaatcgaa gcagtcatcg
    29881 aatctcctgt tgctattgat cagcatcttg taaaagaaaa tgaaacacca aaagcccctg
    29941 ggatgaaata caaacactac tcacccgata cacgtgttct gatggtcaga gatggcgatt
    30001 ggtcaactgc agttcaatgg gcaaaaaata agaagatccg tgcaggtgtc atagcaagcc
    30061 ccgaaattgc ggatcaagtg cggacagata ctgcagctgt ttatatgtat aacgacaact
    30121 cagtagaagc ggcggctaaa ggattgtttg caggtctaag aggattagat gaaccaacac
    30181 ttggattaga tttgattttt gtacaagtgt atccagaaac tggattgggg aatgcttaca
    30241 tgaatcgctt gaaaaaagca gcaggacaaa attattttga aaaatgatca attggttatt
    30301 gtcgcattct tttagtatga tacaatgcta tcaagtaaat cttctatcag tgaacgaaaa
    30361 actaagcgta actaatcgta atagaagaga tacgaatatt tggcaatttg tttttgatgg
    30421 gaaaaataaa attgtaggaa aataaaaagg agctgttgtt tgtggtagat tacaaaacgt
    30481 ttgaccctga tctttgggct gcgatcgcca aagaagaaga aagacaagaa cataatttgg
    30541 agctgattgc ctctgaaaac tttgtctccg aagcagtgat ggctgcacaa ggaagtatct
    30601 tgacaaataa atacgcagaa ggttatccag ggcatcgcta ttatggtggg tgtgaatttg
    30661 tcgatatcgt tgaaaattta gcgattgacc gtgcaaaaga attattcgga gcgaaatttg
    30721 cgaacgtcca gcctcactcc ggctctcaag ccaacacggc tgcttatctc gctttggtag
    30781 aaccagggga cacgatctta ggaatggatc tttccgcagg cggacatcta acacatggat
    30841 caccagtcaa cttcagtggc aaaacctatc actttgttgc ttacggtgtt gatccgacaa
    30901 cagaagttat tgattataat gtggtacgta ttttagctag aaaacatcaa ccaaaattga
    30961 tcgtagcagg tgccagtgct tacggacgaa cgatcgactt tgcgaaattc agagaaatcg
    31021 cagatgaagt aggcgcaaaa ctgatggtag atatggcaca tatcgcagga ttagtagcag
    31081 caggacttca tcctaatcca gttccttatg cagatatcac aacgactacc actcataaaa
    31141 cattgcgtgg ccctcgaggc ggcatgattt tgacaaacga tgaagcatta gcaaaaaaaa
    31201 taaatagtgc ggtatttcct ggtattcaag gcggccctct agagcatgtg attgcgggta
    31261 aagcagtagc attcaaagaa gcattagatc ctgcatttaa agaatatagt gaacaaatca
    31321 tcgccaatgc aaaagcaatg gtcaaagttt tcaatcaagc aattggaacc agagtcattt
    31381 caggggcgac agataatcat ctgatgttga tcgatgttcg cgagttaggt ataaatggaa
    31441 aagaagcaga gagcattttg gacagtgtga atatcactgt aaataaaaac tcgattcctt
    31501 ttgaaacact aagtccattc aaaacaagcg gtattcgaat cggcacgcca gcaatcacta
    31561 ctcgcgggtt caaagaagaa gatgctgtaa aagtggctga actagttgtc aaagcattac
    31621 aagcaaaaga tgataacgct caactagacg aagtcaaaac aggtgtacgc gaattaactg
    31681 aaaaatttcc gttgcataaa aaataaaaat ttaaattcca ttagtaaaca gaaaagttca
    31741 atgttgggct tttctgttta ttttttggga aaacggattc tttgacaata tcggtgatgc
    31801 tctctagtat atgaggtgta attttagtct tcacactaaa tctcagggag gaaaagtcat
    31861 gactgatcgt atctcgttag aaaaggaagc agtagcattc agtgatgcaa atgcgcctca
    31921 tccgcgtatc tatgaactag caccggaaga aggaagagtt ttactagaag aagtacaaga
    31981 atcacctgtg aacaaatatt ccgtcgatat tgaagacttg atggtggata ctggcgaatg
    32041 gggaaaactc aatattcgtc tcgtacgacc agaagggaat atggataaat taccagttat
    32101 tttttatatt catggagcag gctgggtttt tggcagtgct caaacccatg ataaattgat
    32161 cagagaactt gcggttcgta cgaattccgt cgttgtcttt ccagaatata gtcgatcacc
    32221 agaagcaaaa tatccaacag caattgaaca aaattatgct gtgttgcaac agctgaataa
    32281 attagccaag tcaaaaaatc tggatctcga gaatctaatc gttgcaggag attcagtagg
    32341 tggtaacatg gctacagtca tgacgatctt aacaaaagaa cgaaagggcc tcccaatatc
    32401 caagcaattg ctgtattatc cagtcacaaa cgctgatttt gatacagatt cctatcatga
    32461 attcggagaa aactattttt tgacaagaga aggaatgatg tggttttggg accaatatac
    32521 gacgaatgaa gaagagcgtg ctgaaatcac agcttcgcct ttgagagcaa atataaatga
    32581 actaaatgat cttccttcag caatgatttt aacgggagaa gcggatgtat taagagatga
    32641 aggtgaggct tatgcgcgca aacttcgtga tgcaggggtt cctgttacac aagtacgctt
    32701 ccaaggaatc atccatgatt ttgtcatggt aaatgctatg gatcagacaa aggcaacgcg
    32761 tgcagcaatg gcattatcta cttcttggat caagaaaaaa gaataagctt tgcttgtccg
    32821 caggaaaact tcttttcaaa aacggatttt cttaggaaaa atggcgagtt tgactagtca
    32881 atcacttgat tttgttttac aattaaaaag aaacgacaga acaaaggaga gcttaaaaaa
    32941 tgggcaaatt tcaagtgatc gatcatccat tgattcaaca caaactaact attattcggg
    33001 acaaaaactg cggaacaaag gtttttcgtg aagtagtcga tgaaatcgct atgttgatgg
    33061 catatgaagt atcacgggat atgccattgg aagacatcgt gatcgaaaca ccgatcactg
    33121 aaacaacaca aaaaacgttg tctggtaaaa aagtagcgat tattccaatc ttgcgcgcag
    33181 gtattggaat ggttgacggt atcttggaat tgattccagc tgctaaagtg ggacatatcg
    33241 gtctttatcg agatgaagaa acattggaac cacatgaata tttcgtcaaa cttccagaag
    33301 acattgatgc acgtcagttg tttgtagtag atccaatgtt ggcaacaggc ggatcagcaa
    33361 tcatggcaat cgatgcattg aaagaacgtg gcgcgtcgaa cattaaattt gtttgtttgg
    33421 tagcagcacc tgagggagta aaagctttgc aagaagcgca tcctgatatt gacatctata
    33481 cagcttctct agatgaaaaa ttgaatgaac atggttatat cgttcctgga ctaggggatg
    33541 cgggtgaccg tttgtttggt acaaaataag taaatacgaa aaagggtgtg acacaacttt
    33601 tgtcacatcc ttttttggtc atttttaacg tttgatgcag aacagctttt tcacagcttt
    33661 cgtttgcata taaaaaaacc atcccaaaaa tgcagagatg gtcaaattca aatctttttt
    33721 agttctttgt agttaacgat tactacaccc ttactttgcg tcatcaagtt cgcattttct
    33781 gcagtttcat caatctcaac aacagcggaa tttttcaatt gctttgaaat cgttccagtt
    33841 tgcgacttgc cgtgaattgt gaacattacg tgagtattga tcttgaattt ttcaccaatt
    33901 tccgatggta cgatagttgt atcaaatttt ccaaaagttg ccattttcat aaaacctgcc
    33961 tttcacatca attataccac gttttatgaa aaatatcatg aaattaaact aattttccat
    34021 cggactcttt acaatcagcc aaatagagta tataatttct tttggataag gccagcttag
    34081 ctcagttggt agagcaacgc actcgtaacg cgtaggtcgt aggttcgatc cctatagctg
    34141 gcattaaaag agaagacaga tatatcaagg atttttaatc cattgataca tctgtctttt
    34201 tgtttaaagg aaataaagta tgctttctta gcaatagagc atgtattatt tctataaaaa
    34261 tttaggagaa taaaacgact agcaatatag ctgtgaaatc aaatatcaca tgaactgccc
    34321 aacttgtaat gatcgagttg cttttaatgg cagcttggtt gaataacaat cttgccaccc
    34381 cttgtatcaa aaggatgtgt gctacagtgt gtaaaatatt tccattatca taagtactgt
    34441 aatggataaa tccaaagatg attgctgaca agaaactagc gacaggaatg ctgaacttac
    34501 tagaaaaaat agcgagaaaa tacactgaga acaattcttc tccaagtatc atgataggca
    34561 aaataataaa taataacggg ctgaaagcct catttattgg attgcctgtt aaaccccatt
    34621 tcaaaatttg ttgcaaaaat accgagactg cggcactgat tactacattg ataaaaaaat
    34681 atttggctat atttttgaca ggagcgacag gtttcgagaa catttttttc gtatcttttt
    34741 taccaaaaac aagtgtaaat gctataaatc cagtgatagt taaagaaaaa atgctaataa
    34801 tggatggcgc aaatagcaac cctaacaaac cgagtacaac gacaatagtg cccaatatcc
    34861 cttttttaag ttctattttt tttcctaaaa tgttattcat gataataact cctactattc
    34921 agtttttgaa gatagagtca gtatacatga agagttaaaa taggcaatgt ttttttatgg
    34981 atatttgtat tgctaaaaat ttatcttata tattcatttt gattatacta cttttatttg
    35041 taaaaatttt ctagcaaaac caagtgcttg caactgatta agcgtacaat tttttagatg
    35101 ttccgagcgt acttcaatca tttcaaagga gttgctactt aaatcgatat tttttaaatc
    35161 agtatcaaaa aagctagcat tttctaaatc attagtagaa aacattattt tagtgaggga
    35221 acagtctaca aaatctgcgc ttgataagac agagtgctca aaggtacttt cttttatgtt
    35281 tgaaccagat aaatttacat agtccatttt acaattctcg aataacgtgt tcccaatata
    35341 actttccatc aatttagtac ctgttaattt acaattgaca aatttcacgc gatgcaacat
    35401 gctttttgtc aatatacagc ctgaaaaatc acagttttcg aatatacagt cggtaatctc
    35461 cattctttga aaatcattgg aagcaaaaaa tgcatacttg aaaatagatt tgtaaataat
    35521 tggatggcag attatttggt tttcgatgac ctctttttgt gaaaggatat tatacagttc
    35581 aaaatcttcg ttttcataga tatgaaaaaa ggatccttta ttcaagcttg cttcattaac
    35641 tttaggaaaa atcatattta attacctcca ttttcataaa gtcatattaa caaaagctaa
    35701 accaacttac attagcagaa aatgagatag gttttcgcct ttttcgataa cgatagtgtc
    35761 gctatctctt gaaacgttct tagaattgcc ctgagagaca caaattaggc gtaattctaa
    35821 taaaaatctt agaataaaaa tttttactga tttaatttag aatgttttta aaataaaaat
    35881 cgttgccata acagtgtatt gaaaggtttt aacaatccag taatgattta aaaaaatcta
    35941 gatgtagcgt atactttgtt tatagaatgt agtgggaaga aatatatttt tgggaggaaa
    36001 tcgtgatgtc taaaagtgaa gaaatagaaa acatggtact aaaattatat gatctcgttt
    36061 taaatccaga gatcaaagaa aaggaacgta tacttttgat agacgcaaag acaggcttag
    36121 aaaaaggtca gtattatcct aaagtcataa ataatttgga acgtagttta cgtccgttag
    36181 caatcagggg agaattgtct aaaccagtat caccgtttta tatggagata tcaacaatag
    36241 gaaaatttga aaaagaatta ggtcgaggaa tggcttcggc accgattact tttgggcatt
    36301 tataaaaacg agttattcat ctcaatgaat taaaaagtat agtcaatctc ataatgcagg
    36361 ctaggttcat ttatttgaac agagtctgta tttttttatt ctaaataaag aaacagatgt
    36421 ttctttatat tgtattttat cctttaatta acacaaaaac agctagtata aactaataat
    36481 gttaattaaa agtgtatttt atgaaactat cgttatttat taatgttgca tttttg
//
LOCUS       DAIGUC010000027        35492 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.027, whole genome shotgun sequence.
ACCESSION   DAIGUC010000027 DAIGUC010000000
VERSION     DAIGUC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.027"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(144..1622)
                     /locus_tag="NOB46_001416"
     CDS             complement(144..1622)
                     /locus_tag="NOB46_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058356.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1920..2855)
                     /gene="murB"
                     /locus_tag="NOB46_001417"
     CDS             complement(1920..2855)
                     /gene="murB"
                     /locus_tag="NOB46_001417"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCI1058357.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2928..3848)
                     /locus_tag="NOB46_001418"
     CDS             complement(2928..3848)
                     /locus_tag="NOB46_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1058358.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3961..4713
                     /gene="xth"
                     /locus_tag="NOB46_001419"
     CDS             3961..4713
                     /gene="xth"
                     /locus_tag="NOB46_001419"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCI1058359.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5577..6110
                     /locus_tag="NOB46_001420"
     CDS             5577..6110
                     /locus_tag="NOB46_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HCI1058360.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6600..7124)
                     /locus_tag="NOB46_001421"
     CDS             complement(6600..7124)
                     /locus_tag="NOB46_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058361.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7117..7590)
                     /gene="tsaE"
                     /locus_tag="NOB46_001422"
     CDS             complement(7117..7590)
                     /gene="tsaE"
                     /locus_tag="NOB46_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCI1058362.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7713..8693)
                     /gene="pta"
                     /locus_tag="NOB46_001423"
     CDS             complement(7713..8693)
                     /gene="pta"
                     /locus_tag="NOB46_001423"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCI1058363.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8846..9526)
                     /locus_tag="NOB46_001424"
     CDS             complement(8846..9526)
                     /locus_tag="NOB46_001424"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI1058364.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9652..10521
                     /locus_tag="NOB46_001425"
     CDS             9652..10521
                     /locus_tag="NOB46_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1058365.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10547..11062
                     /locus_tag="NOB46_001426"
     CDS             10547..11062
                     /locus_tag="NOB46_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058366.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11109..11702)
                     /locus_tag="NOB46_001427"
     CDS             complement(11109..11702)
                     /locus_tag="NOB46_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058367.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11727..11906)
                     /locus_tag="NOB46_001428"
     CDS             complement(11727..11906)
                     /locus_tag="NOB46_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058368.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11983..12492)
                     /locus_tag="NOB46_001429"
     CDS             complement(11983..12492)
                     /locus_tag="NOB46_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058369.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12588..12968)
                     /locus_tag="NOB46_001430"
     CDS             complement(12588..12968)
                     /locus_tag="NOB46_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1058370.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13298..14047
                     /locus_tag="NOB46_001431"
     CDS             13298..14047
                     /locus_tag="NOB46_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HCI1058371.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14231..15508)
                     /locus_tag="NOB46_001432"
     CDS             complement(14231..15508)
                     /locus_tag="NOB46_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058372.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15587..16231)
                     /gene="pcp"
                     /locus_tag="NOB46_001433"
     CDS             complement(15587..16231)
                     /gene="pcp"
                     /locus_tag="NOB46_001433"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCI1058373.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16430..17374)
                     /locus_tag="NOB46_001434"
     CDS             complement(16430..17374)
                     /locus_tag="NOB46_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCI1058374.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17376..18062)
                     /locus_tag="NOB46_001435"
     CDS             complement(17376..18062)
                     /locus_tag="NOB46_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCI1058375.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18536..18856
                     /locus_tag="NOB46_001436"
     CDS             18536..18856
                     /locus_tag="NOB46_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCI1058376.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            19010..19915
                     /locus_tag="NOB46_001437"
     CDS             19010..19915
                     /locus_tag="NOB46_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1058377.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19912..20685
                     /locus_tag="NOB46_001438"
     CDS             19912..20685
                     /locus_tag="NOB46_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI1058378.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20866..22290)
                     /locus_tag="NOB46_001439"
     CDS             complement(20866..22290)
                     /locus_tag="NOB46_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1058379.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22501..22947
                     /gene="nrdI"
                     /locus_tag="NOB46_001440"
     CDS             22501..22947
                     /gene="nrdI"
                     /locus_tag="NOB46_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI1058380.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(23012..24994)
                     /locus_tag="NOB46_001441"
     CDS             complement(23012..24994)
                     /locus_tag="NOB46_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1058381.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(25008..25904)
                     /gene="murQ"
                     /locus_tag="NOB46_001442"
     CDS             complement(25008..25904)
                     /gene="murQ"
                     /locus_tag="NOB46_001442"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI1058382.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25907..26968)
                     /locus_tag="NOB46_001443"
     CDS             complement(25907..26968)
                     /locus_tag="NOB46_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI1058383.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(27179..27745)
                     /locus_tag="NOB46_001444"
     CDS             complement(27179..27745)
                     /locus_tag="NOB46_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1058384.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(27773..29275)
                     /gene="eat(A)"
                     /locus_tag="NOB46_001445"
     CDS             complement(27773..29275)
                     /gene="eat(A)"
                     /locus_tag="NOB46_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI1058385.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29533..30654)
                     /locus_tag="NOB46_001446"
     CDS             complement(29533..30654)
                     /locus_tag="NOB46_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI1058386.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30780..31721
                     /locus_tag="NOB46_001447"
     CDS             30780..31721
                     /locus_tag="NOB46_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI1058387.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31871..32767)
                     /locus_tag="NOB46_001448"
     CDS             complement(31871..32767)
                     /locus_tag="NOB46_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI1058388.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            33036..34376
                     /locus_tag="NOB46_001449"
     CDS             33036..34376
                     /locus_tag="NOB46_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1058389.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34594..35037
                     /locus_tag="NOB46_001450"
     CDS             34594..35037
                     /locus_tag="NOB46_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCI1058390.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT        10317 a         7236 c         6293 g        11646 t
ORIGIN      
        1 aaaatcggaa taataactta tgtacttttt aattttgtta agtaatatat ctagttatat
       61 ctagttatat ctagttacct tttctttgaa aaaaacataa atcagctaat aaatatgtga
      121 gacaaagctg ccatccataa atactagctg attttttcag ttaaatgtct atttttttct
      181 ctgatgatgg tatttccaaa atattcccag tcatctggag tcggtggatt tttccaaatt
      241 atctgttctt tattaaattt ttcaagtaaa caatcagata aataaatatt cgtacgagaa
      301 gtgattcgac tctcaatcac aatattgtaa tttttaaatc ctttcacttg agaaataatg
      361 taatcggtat aagcagatcc ttgcgaaaaa tcaatacaga catgaatcgg tgcttcaaaa
      421 tatgataccg gacaaatacc gaccaataaa aagagataat cataaaataa gcgaatcatg
      481 aaacgttcat cttttcccaa gaaatagcgt ttattctctt gtatgacctt ttggattgct
      541 gtactgaata ttggatacgt ctcgaagaaa aactgtagct gctttttaga cgtaaagcta
      601 gtcatctcaa agtcgaatat ccaatttttt cgattgacat gcatcatacc catacgaagt
      661 tcttttcgta tatatagtct ttcttcttca gagatttcaa tcgaaaatgg taattgatca
      721 atcaattcca ctgacatttt ttgactaatc atgtggatat catgaaaatg agcttccgca
      781 agtccaaatg cgccatctaa ttcaaattct tcttccgtga tcaaaaacaa catgatataa
      841 gaaatctcat caatgatctg ctctttaggg atatgaagaa aagaaatatg tgataaatcc
      901 ttgatgatct tcattccttc tgagctctta aagtattcat ctgaaaagaa acgttttccg
      961 attggttgat tcccataggc cctcaacaaa ctaatagtgg ttagcaaatt gaatttgatt
     1021 cgttttgttg cagacagttt taaattgaac agatattcaa aatattgcac gatactcttt
     1081 gcttcattca tgacgctttc tctaaatggc atagaaaaac cattaaagac cccgaaatat
     1141 accccaaata atacgttccg tatgtttatt tcttccccaa ctaatatgtt tttctttaac
     1201 tttatttgat gctgttcaag aaaagagact aattctcttc tttttacata ggctcttgat
     1261 atgcttaaaa aatgattctc tgcaaatttt tcgatcgtta cttttgaatc cacgatctcc
     1321 gttaacagtc gagcaatttt tgatcgttga aagtagattc ttcttaaatt tttgatatcc
     1381 gtcaaattca gacgttcgac atggatctct gcttcttctg aaatttggat ctctggcttt
     1441 gttttgaatt cagtaaattc tttatttaat tctatgatat aatttcttgt tttaaattta
     1501 gacaaaccta atgtttcata taacttaggc agcactacat aattcttttt ctcaaattct
     1561 aaatatctag ctagcagcag tttttctcta tcttcctctt ctataaggta atccaacttc
     1621 atatcctaca cctcaaaaaa tgcctcatac caattacttg atatgcagat gaaagttcat
     1681 cttttcacct atactgattt tatgatggat tatgcttgtt ttttcatcag ttattctcat
     1741 tttttatctt ttttttgaga atattgcaaa aaatggaaaa atttatgagg aaatattcta
     1801 tattttttgt tttattgtgt taaaatgtac aagatttgcg ccatttgcgt aaacaaccac
     1861 aaaaaagagc aggacggcca ccgtcctgct cttttactta ttttaagttc cattacttat
     1921 taattggcta aacttctgct tgtttctgat attgcttgtt tttctccaat gatccgcact
     1981 tctgtttcta aagacacatc aaatttttct ttgattactt cttggatgtg cgcaatcaat
     2041 tcaatataat ctgtcgctgt cgcatgatcg atattgacga tgaatccagc atgtttttca
     2101 gagacttgtg caccgcccca tttcaggcct tgcaatcctg cttgttggat cagctgacct
     2161 gtatagtgtc ctactgggcg cttaaagaca cttccgcatg aagggtattc taatggctgt
     2221 tttgattgac gcaattcggt caactcatcc attcttgctt tgattgcttc ataatcccct
     2281 gtttgcaaac tgaatcgagc ttccaatacg atagcacgta attcttggac tttactgtga
     2341 cgataagaaa ataccatttc gtcttttgtc aaagttttca atgttccatc ttcaagcaaa
     2401 agatccactt cagcaaaaac atctttgatc tctccgccat acgcacctgc attcatataa
     2461 accgctccac cgacacttcc cgggatgccg caagcaaatt caaatccagt caatgattct
     2521 gccaaagctg cataagtcgt atcaatcagt gaggcacctg cttccgcaat gaccatcgtt
     2581 cctttgacat gaatctgttt catttcagtc agcatgatga ctacaccgcg aatcccgcca
     2641 tcttgaacga tcagattgct tgcatttcct aataccatcc aaggtatatc atggattcgg
     2701 caataatcga tgatttgctt tacttcttct tgttttttcg ggaatgcaag gacatcagct
     2761 ggtccacctg ttttcgtaaa cgtatagttc atcaatggtt catcaaacaa tatagtaatc
     2821 gtggctaagc tttcaactat ttcttcttta ttcactgagg attttccttt cttttctcaa
     2881 acgtcctcat tattctatca cgcttaatac aatcttgcca gtcttgttca aagttgatga
     2941 cggtagtgat ctttaagcac ttcctcacat aattcatgac ttcttacaac ttctttttgt
     3001 ttaagcaatt ctgtttccga tttacctaaa cggatctgag aaaagaaggc ctctaccatt
     3061 ggctcaaacc cgcgtttgac tagcgtgttt gtccagtcgc caaattcttt cacttttttt
     3121 ccatcagcat cttgaatgac aagctgggtc agatcgttta cttcataagt accattttta
     3181 cttgttactt gatatttttc tatattagcg ccacttgcta aatccatcgt taaaatagcc
     3241 gtttgatttt gtgtttctaa ttgtaaaatg gcatattcca aaaattcctt tgtttctctt
     3301 atctggtatt ttgttctcaa aatgggttca tctaataaat acacagctgt atcaataaga
     3361 tgtaaaaaca aatcataaag gacgaactct gtcgtttctt ttgccgctat tcgatttttt
     3421 tgcaggtgga tcaaccgctt atctgggata cgtttcaatt cttctaccat aggagcaaag
     3481 cgccggttga aaccgatcat caaaattatt tggttcttat cagctaattc ttgcaattca
     3541 cgaacttcat ttagatggac actcagtggt ttgtcaatat aaacatggat accattttct
     3601 agacattttt tggctaattc ataatgtact tttgttgctg cgtggatcat acatgcttcg
     3661 attttttctt ctaaaagctc atcgatcgtt tcatatagat gttggaaccc gtactctttt
     3721 tgaattcttt cttttgtttc tttatttctt gttgcaaaat aaaaatcaag tgttccttgt
     3781 tttttcgcat aagttggtaa atatgctttt tctgcgatat tccctacacc gattacacca
     3841 atcttcatct actttcctcc tggatcattt agttactttc atcttacacc attttttact
     3901 aaaatgaggt acaatagtat cgcaaaggta aggaaattaa ttcgaaggag tgtgctttta
     3961 ttgaaattta tctcttggaa cgtaaacggg cttcgtgcca tcgtaaataa aaatttttta
     4021 gaagtttttc atgagttaga cgccgatttt ttctgtctgc aggaaacgaa actccaagca
     4081 ggacaaattg atttagatct tccaggttat tatcaatatt ggaattacgc ggaacgaaaa
     4141 ggctattccg gcacagcgat ttttgctaaa aaaccagcat tgaatgccac ttacggaatg
     4201 ggtatcgata tccatgatac agaaggccgt ctgattactt tggaatattc cgatttcttt
     4261 cttgtaacct gttacacgcc aaattctcaa agcgaattaa aacgtttaga ttaccgatta
     4321 gaatgggaag aagcctttta taattatttg gaaaatctaa aaaaacaaaa accagtcatc
     4381 gtgtgtgggg atctaaatgt cgctcatcaa aagattgatt tgaaaaactg gaaaacgaat
     4441 caaaaaaatg ctggattcac tccagaagaa agagcggctc tttctcgact gttggataac
     4501 gggtttatcg atacattccg ttatttttat ccaacccagg aaggtgtcta ctcttggtgg
     4561 aactaccgat tcaattcaag gaaaaacaat gctggttggc ggatcgatta ctttttgacg
     4621 agcaaagatt tagagccagg actagctgat gcaaagatcc atacggacat tatgggcagt
     4681 gatcattgtc cagtagaatt agatttgaaa taaagaggtt gtgaaaaagt cgtttagttt
     4741 cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat tttgcataaa tttggcataa
     4801 taccgagaaa ctggcttttg aacactgttt atcgagagat tgtgaaaaag ctgtcctgca
     4861 tcaagtaata agaacagcca aacaaaaata gttcctcata tttttcgttt ggttgggctt
     4921 attaccgcag atacaagctt ttgaacaccg tttattaaga ggttgtgaaa aagctgcact
     4981 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atatttttcg tttggttggg
     5041 cttattaccg cagatgcaag cttttgaaca ccgtttatta agaggttgtg aaaaagctgc
     5101 actgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt tcgtttggtt
     5161 ggacttatta ccgcagatgc aagcttttga acaccgttta ttgagaagtt gtgaaatcag
     5221 cgtcctgacc tgagtattag agaaacaaat ggcaaaatag ttcctcatat tttgctattt
     5281 tttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaag ttgtgaaaaa
     5341 gtcgcctact ttcgagtcgt aagaaatttt tttgaaaatg gttcctcaca actttgcata
     5401 aatttgactt aataccgaga agtcatgatc cccatctaac tccaaatcac aaggaatgag
     5461 ttcaaaaact agcttttctc aacaaatatt acataaaaaa ttctatgttt tttgttaaat
     5521 ttatttgctt ttttcaaaag tatgttacag taatttccca aggaggtttt acagaaatga
     5581 attttgttgc catggatttt gaaactgcca atcatcagcc ttatagtgct tgttctcttg
     5641 cgctagtcat ggtaaaaaat agccagatcg ttgatgaatt ctatacattg atacagcctg
     5701 agactccttt tttctggcga aatgtccaaa ttcacggaat ccatcaagaa gacgtacgca
     5761 atgcgccgaa attcccagaa gtctggcaaa ctatccaacc atattttcaa aaaaatcgtt
     5821 tagtcgttgc acataatgct gcttttgata caaaggtctt agcgggatgc ttagattatt
     5881 atcatcttga acagcctaat tatctttctt tatgtacagt gaaaagtagc cgtcgcctgt
     5941 ttcctgaatt tccaaatcat cgattgaaca ctgtgtgcga aaatttgaac atccaattag
     6001 atcatcacca tgatgcattg gaagatagtc gtgcatgtgc ggaaatcctg ctttatcaag
     6061 aaaaaaaatt cgggacagat ccattgaaaa aacttgtgac tataaagtaa aagaatactt
     6121 atgaaacaca caaagaggtc gtgagcctgc cgtttcactc cgagtcacaa ggagcaattt
     6181 caaaaaatag cttctcatgt ttattaaata ttgtgactgg tgaccgagga gctggcagga
     6241 gaacaccgtt tattggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
     6301 caaacaaaaa tagcttctca tatttttcat ttggttggac ttattaccgc agatgcaagc
     6361 ttttggacac cgtttaccaa gaggttgtga aatcagcgtt ttgacctgag tattagagaa
     6421 acaaacggca aaatagttcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
     6481 tgattgaaca ccgtttattc aaaaaaaatg gactgcgaca cgacttttgt cacagtccct
     6541 tcgtgtgttt ttctgccttc tcaaaaggat gacagtttct cactcttttc ctatttcttc
     6601 tattcaatca aataactcat tttatataca tctaaaaatt cacctagatc tgttcttgcc
     6661 cctctaggca tgaccgcttc gatttggaag cccatttttc ggtaaaggtg tacggctctt
     6721 tcattacgaa cttgaacgtc aagctccaat cgaaaaagta cacccatttc cttcgcccaa
     6781 ctgatgattt cttctagcat aagagtgcct agtcccattc cccaatattc ctgcagaata
     6841 ctgataccga cttctcccac gtgagacaaa cgaaattgac tgtctgcctt gacagatgct
     6901 gttccaataa tcgtcccttc atagattgca agcagcaata aattattatt gctttcgtat
     6961 atataatcca actcttcttc taaggtttct ggtggtaaca ggagttctgc ttcatccaaa
     7021 actaaaaatt ctgtctcctt attaacttgt cccatcatca aaagaatgtc ttttgcatct
     7081 cctggcactg cttcccgcaa gatgatccca acttcttcac tcatgatttt cagcccattt
     7141 ttctagaatt cgctgtttga aggtttcact ttgctccccg tatgagatta gtttcacata
     7201 ccgcttttct aaatctgtat cacttttttc taaaatcagt tccaaataat cctccggcag
     7261 tgcttcttct aatagatttc cccattcaac aacggaaagc ccatcacctt caaaatattc
     7321 atctaaccct aaatctgctc cgctagctgc tacccgataa atatccatat gatacaacgg
     7381 aatccgacct tgactatatt ctctaataat cgtgtatgtc ggacttttga tcatttgcgt
     7441 tatccctaat ccttgggcaa ttcctttcgt caacgttgtt ttacccgcac ctagatcacc
     7501 agtcaatatc agattgtcac ctggcattgc ggaatgacca attgcctctg cgaattgttc
     7561 tgtcattgtt aatcctgata gttcgatcat ttttcatctt ctcccgctct tctttctttt
     7621 tgccagtata tcgcgtaatg aagttttttt aaagaaaaaa tgaactagtc aagaacagca
     7681 gctgctgttt ttggctagtt cgcgtgtatt tgttaatcaa tcaatgtttg tgctgctgtg
     7741 ataatcgata atttatatac atcttcttca tttgctccac gagacaaatc agaaaccggt
     7801 ttgttcaagc cttgtagaat tggtccgatt gcttcaaagt taccgaaacg ctgagcaatt
     7861 ttatagccga tatttcctga ctgcaattct ggaaatacaa agactgttgc ttgaccagct
     7921 acttctgaat ctggcgcttt cagttgtgca actgaaggaa cataagaagc atcaaattgc
     7981 aattcgccgt cgatcatgta ttgtggcgct agttttttag cgattttagt tgcttcaact
     8041 actttgtcta cttctggcga tttcgctgag ccttttgtcg agaagctcat cattgctact
     8101 tttggttcga tatcgaacaa ttctgctgtt tttgcagaat ctacggcgat ttcagccaat
     8161 tcttgcgcag ttggattcac gttgatcgca caatccgaaa agacatattt ttcttgatct
     8221 cttccacgta ccatgatcat cgctccgctt gtccgactga tgccaggctt tgttttgatg
     8281 atctgaagtg ctgggcgaac agtgtcgcca gtcgaatgga tcgctccaga gaccattccg
     8341 tctgcaatcc ccatatacgt aagcatcgta ccaaagtaat tcacatcttt taaaatcttt
     8401 tctgcttgtt ctttggatgc ctttccattt ctacgttcaa caaaagtatc caccatttca
     8461 tcccacttat cgtaattatc agggctgatg atcgtaaagc tagatgtttt gattcctctg
     8521 gcatgcgctg catttcttat ttcttcttcg ttccctacta aaatgggttc cacaagttct
     8581 tctgctttca accgggcagc tgcgcctaaa atacgagcat cagtagcttc cgggaaaacg
     8641 attttgatcc cacggcgaac aattttaaat cttaaactat caaacaattc cacaagatga
     8701 cctccagacg tttttatatg tattatcata cactattcca gaaaaaaaga acagtttatt
     8761 ttatctgtat cagtcaaaaa tgctggaaaa attaagtttt tcacatacaa agcgaactgc
     8821 actataacag gaaagcgctg ttttattaca ctgtttcagg cagttgccaa tcaatcggtt
     8881 cttctcctaa cgcaaggagc gcatcattcg ttttcgagaa gggtttggaa ccaaaaaagc
     8941 cacgacttgc agataacgga ctgggatgtg gagatgttat gatgatatgg cgactcttat
     9001 cgatcatttt gattttttct tgtgccggtt ttccccacaa gataaacacg attggttttt
     9061 cccgttcatt taatttttca atgatcgtgt ctgttaatct ttcccaacct ttcccgcgat
     9121 gagaatacgc ttgcccttcc cgaacggtaa gaacggtgtt gagtaaaagg actccctgtt
     9181 tagcccatga cactagattt ccatgttgaa caggtgcgat tccaagatca tcataaagct
     9241 ctttatagat atttcttaac gatggcggga tctttacgcc aggttgcaca gaaaaagata
     9301 agccatgagc ttgattttct ccatgataag gatcttgtcc taaaatcacc actttaactt
     9361 cttcataagg agtcaattcc aatgcttcat agatatgata catatctgga tggatctttt
     9421 gggacgcata ttcttttttt aaaaattctc ttagatgcag ataataatct tttgaaaatt
     9481 ctgaggacaa aacttcttgc caactgttat gaatgatttc tttcaaaaac tccacctcct
     9541 aataaaaaga ataactcaca ttttcttcaa tcacaaggga caatcttcac cctcagcact
     9601 tgattaatat ggtaaactag gaacaagaag cagaaaggaa cgataatcat tatgatcaaa
     9661 ttaattgcat cagatatgga cggcacatta ttagatgccc atatgagtgt ttctcctgaa
     9721 aatgccgagg cgatacgttt tgcaaatgat gccggtgttg agttcatggt cgctactggt
     9781 cgaaactatc aagaagctcg cgcagcttta gatgaggtag gaatcgattg tgcgatgatc
     9841 actttgaacg gggcacaggt atttgataaa gaaggaaatt cattgtttac cgtgtcgatt
     9901 ccaaataatc aagcaatctc tgttttagat attctagatg ctaacggtat ttactatgaa
     9961 gtagcaacca acgatggtct ttattctgaa aatcaagcga aacgaattga aagttttgct
    10021 tccatggtgg ctacccattt acctcacctt acgtataaaa tggcgattgc catggcctca
    10081 gctaagctgg agttattgca catcacatac gtggacagta ttcgtgctat tttggaagaa
    10141 aagaatctgg aagttttaaa aattatttgt tttcatacag aagggccagc tgtattaggt
    10201 ccagttggaa agcagatttc tcttttaggc gatctagccg ttacttcctc tggtcaaaac
    10261 aatatcgaag tgaaccataa aaacgctcaa aaaggaattg ctgttgccca tgtcgctcac
    10321 gagcgtggga tttctttaga agaagtcatg acgattggcg ataacttcaa tgatgtcagc
    10381 atgctgcaag tagcaggagt cagtttcgca atgggaaatg cagaaatcga agtaaaagat
    10441 tatgccaaat atacaacgga cacaaacctt gaatctggcg taggaaaagc catattgcgc
    10501 gcgattgcag aagacttgta gttttatcta gaaaagaggg atatagatgt cagaattttt
    10561 cattcaggaa aagcagcttg gacgtgcaac tcggacaatt gtcaaaaacg aaaaaggaca
    10621 ttccctgttt ttgatggttg gtcgctgggg aacaaagggc gatgcattgt ctctttatgc
    10681 catgaatggc gatctcgttg ctcacatcaa gcagataagc ctgacattcg gtacgcgttt
    10741 tgagctgtat aaagagttcg aaaaggtggg aaccatgcag aaaatattca attggcccgg
    10801 tgacttttat tatattcgta gacttcactg gacagtccaa ggtgatatct ataatcatca
    10861 atatcaaatc catcatttca atcagcaaat catgaaaatg gataaagcaa cacttttttc
    10921 aggagattac tatgtattgg atgtctcaaa tgatgaagat gctccagttt gtatttgtat
    10981 tgctgcggtt ttagattact ggctctaccg taaagacaaa agtcgcgata agcctgtttc
    11041 ttaccgactt aacttaagtt aaaaagatgt acctgaaatg cggaaatacg catttcaggt
    11101 acatcttttt agatattctt ttgcatatga tcataaagat gaccactgat catccgctga
    11161 ccgacaactt tgaagtcatg gcgttcgtat aattttttag cctttggatt tttttcatcc
    11221 acacttagac cgatgacgga gcgattagct ttcttcgcca atttaggtaa tgcttctaat
    11281 aatcgcgaac cgatgccttg tcctctaaaa tcttctgata cactgataga gtccaaatac
    11341 cattcgttgg gaaacgtttc tttatcaatg aacaaacgtg tagacgcatc tagctgatat
    11401 ttctctaaga taggtaccag tggctgatcg atgattgatt cttcttcatc tgtataaccg
    11461 taagcaactc ctgcaacttt accgtctatt tcttctacga tacctcgtga ataactgtaa
    11521 cgataatttg gatcagtgat tgcttcttct aaaatctcta aagtcttttg ttcccctgtc
    11581 tgcttcaaaa atggcagttc catatctttt agaatcacta agatcaatgg ggcgatttct
    11641 ggagcatctt cttttctcgc aaaacgaatc atagtttcct ctccttttct ccattctaac
    11701 atgcagaaaa agaaatcgca aaatcgttat tttaaaaaat cttcaatctt ttcagtaatg
    11761 aaataaccat gagtaacgat tcttgccgct tcagttcggc aataagggca gacgactggc
    11821 atttctttat cattatgttc gactacatta ttgacttctt cgtatgcaaa tttttttccg
    11881 caattagggc atttcatttt ttccatgtta tctcaacttc ctttcatctt tactctctta
    11941 gcttactctt atattgtaaa aaagagaagc aatatccttc ttctatgcag atatccatac
    12001 ctgacggtcc tgttctccat ctattaatcg gactttataa taaggacgtt catctttgac
    12061 tagaagtgtc cactctttca cttttgcttt tttcccgtag tagctgactg cttccttcat
    12121 cgctgcttgc ggttgtttga actcttccgt tttttctata tcaaaaagat gttctgcggc
    12181 cttttccgtg tcatttcgta cggttgtttt cccagtggat ggattgactg ctatgacttg
    12241 tccttcacaa aaaaactggt attcatatgt tgcattcgta ggattctcca aatctttttc
    12301 aactgcaaaa tgaatagcag atatgttatg ttcttttgtt tcgtttttta cgattgctgc
    12361 tgcttttttc aatgagatcc gatattcctg gtcactaata tcatccatgt gaaaagcggc
    12421 attgagcagt cccgtcatac cggtaatccc tattacgatg agggcagcaa caccaaacat
    12481 catttttttc attcttcatt ctcctgtttc ttttttttaa agaatatcaa gaaatgaacg
    12541 aatgaaaaat cgaatgaaac gaaaaaaaag tgacaatttt gttatcttta ttcgtgcagt
    12601 tctaatggca atccgtctgg atcaaagaaa aacgtcattt tttttcctgt aaaggtatct
    12661 tctctaatcg gttctgattc gatccctaag gactgcaatt ctgcaattgt ttcttcaata
    12721 tcgtctactt tgaaagcaag atgacgcaag ccacaagctt ctggatagtt tggtcgttgt
    12781 ggcgcattag caattccaaa aatctccaat tcagcacttc ctagtttcag atctaattta
    12841 tagtcatctc gttctttgcg gtaattttct ctgattactt caaatcctaa tttattaaca
    12901 taaaaatcac gtgatttctg ataatctgaa acaatgatgg ctatatgatg gatcgttgta
    12961 aggttcatat gagcactcct attcttcgtt taagctcgga tctatattaa tctccagttc
    13021 cattgtaaat gtgtcagatt gaaaaaaata gctgtttttc ctttttataa gaaaaaaggc
    13081 aaaaaaaaca gaaagtaggt cctccaagac actcttcctg ttcccaatat aataaatgaa
    13141 agtaagaaat tatattttca agaaaacaaa cagaaaatta tcataacaca aattatttat
    13201 aattgaaaga ctagtttttt ttcaagaaaa gcatacaata gattgtgtta gtaaatacag
    13261 aacacactac atttagtgtc ttaaggagtc ctcatacatg aagtcatatt ttcagttttt
    13321 agctcatcag ctaaaaggct ggccgcaaca aaattattat cttttctttt tcagtcttgg
    13381 ctgccaggtc atgactcttg tcaatagtcc catcacttgg ctgtccgtta ttacatttat
    13441 cggtaccacg cttggtgtat tgtgtatttt atccatcaat gcggcaaaat cagtcaacgg
    13501 tattttaggt attttgtctg cgatttgttt tattatcgtt gggttttcag caaagaacta
    13561 tttaagtatc ggtgaacaga ttgcttatat gatcacattg gatatccccg tattgttaag
    13621 taaagaatgg aatcataata tggcttcaaa aatccgaaaa ttcactggaa aaagctggtt
    13681 tatcgcaatc atcagtactt tccttgtcta tcttgtttca ggattcctga ttggtcgtta
    13741 tacagatgat cctcggccgt gggtagatgc cattgctttt tctattagct tgactgctgg
    13801 tatcatcagt ttcttgcgtt acaacaacca atattactgg tggttagctt cagggcttgc
    13861 tcaaatggtc ctttggtata tttcatttac gcatggatct gcaagtttgg cgatgttcgt
    13921 gaacagctct gtttacttgc tgaatgatgt ccttgcattt accgtttcac cttggtataa
    13981 ccaaaaagaa cgtgaacgta tgcaaaaaat ggaagaagaa tactacaacg cacaacaaca
    14041 cgcataaaaa aactgagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac
    14101 acgtataaac ggcggaatca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat
    14161 ttgaaaagca attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag
    14221 cctctatttt ttatagtaat tccttcagat actttcttgc ctcatcattg aaacgcagtg
    14281 attcttctaa cttctgataa tattccaacg cttgtttctg agcttcagta aaacgataat
    14341 gttttccttt ccatttgtcg attgtctctt gcacatttcc agattggata tctttcacta
    14401 ctagttgcca tttttctttt gagactgtac ggtctttctt atcagcagat tgtatagctt
    14461 ctcgttcttt acgcaatact tttaaaaaac catttctgac tatccgagga atgctgtcga
    14521 agaacccttc tgtaaaacca tagcgacaat attgcttcca aataaataga tagatttttg
    14581 gttggatgaa tcgttggttt ttcgcaaaat attccatctg agcagtgact tctggtgttc
    14641 gttgacgttt tgtctttctc aacacggaaa taaatgtttc aaaataagca ttaggatgta
    14701 ctggcacttc ttcatatacg atggattgcc aatctttacg taaaaatgcg cgatagttga
    14761 tcaagaattc ttctacatcc tttactaatt cttctgcaaa gtcgtcaaat agttcttttt
    14821 ttatctgtcg cttttttgac tgcccattga tgtgttcact tattttcttg atttcatttt
    14881 ccaatgcttg ataatccgct atgtaaatcg gcatttctac ttggcgaaat tctgcgagcc
    14941 gctgagctaa ttttatatcc ggtaaatatg gctgtttcat ccgacgattt tggtacaaga
    15001 caaaacagta tttttgccat agtccttcag gaaaatcgat attcttctgc ttaagccata
    15061 ataattcgtc taaggccaga tcaacttttg tcattccctg atggatcgaa gctgccactg
    15121 tcggagagac atgcaggtga tcggcaaagt ggttgatgcc tagttttagg atctttccgg
    15181 tttttggcga tttaacgatg tattgcactt ttaattctct accacactca caatacaatt
    15241 tttgctggct tcgttttgtt cgaaaaaacg gattgatctt gaagtcagaa aacacccaat
    15301 ctgttgcagc taaataatgt tcttccataa aacgagagct gattagatat cggcggtgct
    15361 tatcgactag ttcccgctgt tttttcgtta attttgcata gatctcccaa cgttgactgc
    15421 ttgtgtattg tttagaaatt ttgatgggat agcttttgct gatttctttt ggaaaccatt
    15481 cttcaaagac ggattgccat tcttccacgg ctgtttcttt cctttctaat tacaaaaagc
    15541 tggctactaa cataacgtta gcaaccagcc agtgtttctt gctaaattag tgagttgttc
    15601 cggcatttcc ggaaatatct tctttatttt ctactgctgc ttcaactgca taagtcaaag
    15661 aagaagcaat gtcttctaaa gacatagaag gcgtacccac tggacgatcg atcacttgat
    15721 cgggtgagaa tggcacgtgg atgaacccac ctcgaattgc cgggaattgt gtttcgatca
    15781 aatgaagcaa acgatacatg atatcattgc agacaaatgt tcctgctgta taagagatgt
    15841 acgctggtag accatgatct tgtacatttt ttgtcattgc tttgattggc aatgaggtaa
    15901 agtaagcggc tggaccgttt tcttctaaag ccgtatcgaa tggctgattt ccttcattat
    15961 cagggattct tgcttctgct agattgattg cgacacgttc gaacgagact gctgaccgcc
    16021 cacctgcttg tccgacacag atcacgacat ctggttggtg ctgttggatg gcttctttga
    16081 ctacttgact gcttttttcg aatacggtcg gtacttccac tttgatgatt tcagcaccgc
    16141 tgatttcatc tggcattttt tttactgctt cataggctgg attcactttg tccccaccaa
    16201 atggatcaaa acctgttact agtactttca tctgttgttc ctccgtccga ttgatttaac
    16261 atatggttat cttttatcat accattttcc ttgaacagcg taaataaagg aaacaatagt
    16321 ttaaataaca taacagatca aacttaatat attcttataa aaaaatagtg ttccactaca
    16381 atgttagaag aggttgcgac aattattctg tcacaacccc tctcttctat tatttaaata
    16441 gaatcatata agcaatttgg aaaactagca taaataacgc aataaacaac tggtttttga
    16501 tcactccgta tttgtctttc atctccagca tcgctacagg cacgatattg aagttagcag
    16561 ccatcggtgt cagcagggtc ccacaaaaac cgcaagtcaa tgcaaccatt cctattaacg
    16621 ctggattcgc tccatgacta aatacgaatg gtgcaccgat cccaaccgtc atcacggtga
    16681 tggccgcaaa tgcattcccc atgattaccg taaatatcac catgccaaga gcgtaaatga
    16741 tgatgccgat gttcacattt ccttctggaa cgatcgtacc tactgcattg gaaatcactg
    16801 tcccaactcc agcgcttgta aataccgcac ctagagaagc taaaagcatt ggcaacatgc
    16861 ttaacggccc tactgtgccc agcatatctg ctgcatcatc taaaaatgta cttggtcgat
    16921 tatctcgaga aaagaacatc aagattagca tggctgcaaa aacaccgacg cccacgccga
    16981 ctaaagcacc taaattggta aatagagcaa acaagatcgc aaagacaccg atactcaaag
    17041 ctggaataaa aattttcatt cctagtttgt ctgacatttt ttccatatat tcttttgatg
    17101 gaagccggct ttctcctttg ctgactttct tagcaattgc tggtatggtc atcgcaaaga
    17161 tcaagccacc gttcacgatt gccggaagcc atcttcctcc tgcaataact acccctaaga
    17221 ccgtccagaa aaaggctgac ccataacgat gaggattggt tttatctgtt aaatttctta
    17281 ctccagtgta aatcaatacg agtcccatca cgatataaag gatctccagt aatttatcgc
    17341 ctaataaaat atcaggattt gtaaaaaagt ccatcttatt gcccctttcc tggataatat
    17401 ttcttcgcta atttcttttc tttaagatag aagtagacac ttgccacaac taaagccgtg
    17461 atagccactg gaacttccac taaagcaagc tgtcccaatg ttacgtcata tcctagatct
    17521 ttcagtgttg attggactag caacgcccct gctcctccga tgaatagtac ttggccaaag
    17581 aaccagcaga cattttccat agctgaagcc atacctttta gttcttcttc atgcttagga
    17641 tggacttcta acccttttga ttcgatggtc cccaatgcca tcggtaaaat gattggacga
    17701 acaaatccag caactccacc aaaactcacg ttaaaagccg caaagatcat tcgaaagatc
    17761 ccataaatat ctacaatcat accagcagat actttcttga atcgcttgat caaggaagcc
    17821 gctgattctt tcagaccatt tctttcaagc gttcctgttg ccaacataat gatgataaaa
    17881 atcgccatcc cgcgattgtt tacaaaactt gtacctaaaa gttctaacat tccttgaatg
    17941 ccaagaccgc cagtcaaagc tgtaacaact aaagcaacca ttacgatcaa tatcgagtct
    18001 aatttaaatg caaacccgag aataacaatc aagacgccta aaaggctaag ataattttcc
    18061 atatattttc ctccataaaa tgacaatatt tttttaatta taaagcaaaa cacataaaaa
    18121 atatagttgt tttctcacga aatagacact atttttaaat atttttcgtt atttttttat
    18181 cacaaaaatt atcttactta ttgtaaggta aagctttttt taatttattg cccgataata
    18241 tatagaaata aggtctagtt actgtttttt ttaaatgatt aataaataac aacttctttc
    18301 tatgaaattg caaagcattc atcttctttt ccgctaacga tatatccgtc agtgcttggt
    18361 acactttact aaaaagtatg agattgccga tatctggata ggtgtgctat actacagaaa
    18421 aagatataca atctgccacc gggtaggata aagaggatga tcattccatt aggtctttga
    18481 agggatgatt ttcctctttt tgtgtatttt tttatagtta aggaggaatg taagtatggc
    18541 atggatggaa ttaatcatag caggaatttt ggaagtattc tggtcaacga tgatgaaatg
    18601 gagtgatggt ttttctaaaa tcaattattc tttttacaca gtgattggca tgattgctag
    18661 tttttacttt ttgtcaaagg caatcaaaag tttgccgatg agtctctctt atcctatctg
    18721 gacagggatt ggcgcagttg gttcggtcat aattggtgtg gtcttgtttc atgataagct
    18781 gaatctttcc acttggttct ttgtggggat gctactcatc agtatcattg gcatcaagat
    18841 tactagcggc cactagacac ttggaataag tactgatcag aaaaaataag cctttttatt
    18901 taatattcaa tttttttatg aaaaaataag aaataagtcc aatgacctag cgacttctcc
    18961 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    19021 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    19081 tagcttatcc cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    19141 gatcatgaaa gctattttag gactgatcca ttactcagat ggaacaatct gtattggtga
    19201 aaatgagatt tctccctcta gtcataaagg gttggaacaa gtaggagcat tgatcgaata
    19261 cccgggtatc tatccattct taacaggcta tgatcatctg aagttattct ctgaaaccaa
    19321 cgatgtatct gctatcgaca ctatcgtgaa tcagctcaag atggaaaagt acattcacaa
    19381 aaaagcgaaa tcctactcgt tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    19441 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    19501 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    19561 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    19621 aaagatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    19681 tatctctaca acaaatgatc tagctgctcg aacgatcttg acagaagctg gatatacttt
    19741 ggaagatcct gataaaatca agcttttaaa agaaaacgaa gaattattag gaaccgtgat
    19801 ccagctattg tctgcacaaa atatccatgt gacagacgtc cagcatctga cgaatgattt
    19861 ggaatcttct ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacattg
    19921 cttgtaaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    19981 ctattagttg ttttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    20041 gatccagttg aaatgactgc tcagcttttt agtgccacat cttggattgt ctttatcatg
    20101 attgcagctg caagcacgat catttcgatg gaagcacaat atggtacatt gaaaaatctc
    20161 ctttatcgaa agtattctcg aggagaaata ttagtaagca aatggatcac attagttatt
    20221 tattctgttt atttatacct tttagctatt attgtcactg tgttgatgaa actgattctt
    20281 ttcccttcga tttccttcac ggagaaggtt tctactggtc aaacactgat ccaaagcttg
    20341 ttcacttata ctttgggtag ttatatcggt ttatggctga ttttaagttt agtgttgatg
    20401 attgcttgct ttatcaatag ttccggcgca tccatctcag caggaatcgt cttttatttt
    20461 gcttcgtcaa tcatatctgg tatccttatt gcactcatcc aaaaatggga gtggatcaaa
    20521 tggaatccga tcagtatgtt gaatctgcaa aaccaaattg gaaacgaaga gatcatgaag
    20581 caattgactc atctttctac taatcaaatg ctattcggta atttagctta catcgttttg
    20641 ttcttagcat taggatatct cgtatttaag cgaaaaaatg tatgatgact catcaaaaaa
    20701 gaggctgtga aagagacgtt cagccttatt gccgattggc tgtctcttaa acaccgttta
    20761 ttctgaaaaa ggagctgtga caacatttgt gtcacagctc ctttcctagt atgtttttga
    20821 ataaacgaca ggctcacaac ctctctttat acttctttta tacttctata cgtgaagcat
    20881 cccagtggca aataaaacca ttgcaatcac tccgaccatc gtcacaccta taagtaaaat
    20941 cttatctaag tggatatgtt gtacaggctc gttttgctcc ttacgtgctt tgaggtaaaa
    21001 ataaatgcct ggcaagaaaa gaacaagaac aagcattact tcattaaagg ctacgactag
    21061 catagcccat acttgaaagg cacttgctaa aagccctact aaaaattgga cccattcttt
    21121 ccgctgataa gaaagtttca tttggtacaa tcctaagaaa agccacgtga agaaaatagc
    21181 tgctgtacca agtgtgtaag caaagttata agcactgtca gtgaataata atgaaagtaa
    21241 aaagacattc gtacataacg tcgtcaatac gatagcataa gttggtgccc catttttgtt
    21301 gagttttccc catgctttag gcaaaagtcc gtcttcagcc atgtttccca ttgtttcaat
    21361 cggtaagatc gtccatgaga gccaaacacc aactaaagaa atgatcaaac cgccgttgat
    21421 cacgactgct ccccatttac caaccatcat ttcaaacaca tagcccatag caggctgcgc
    21481 cttgatcgtt tgcagctgat tcatcgtcat tgtcccatat ggaagcatgg aaaccaagac
    21541 gtaaataata atcaagccga atatccctag aatcgttgct ttcccaacat ctgattgttt
    21601 ttttgctcgt gaacctacga cagaggctcc ttcaatacca acaaataccc aaagcatcac
    21661 catgatgcaa ctcaatactt gactggaaaa cgggatcggc tgtccattcg cattcaatat
    21721 aatgtcgcta gaaaagttat caatgaattg ttggatcgaa aacgtgctga tagctactac
    21781 aataaataaa aataatggca ctaatttaca gaatgtgacg atagcattga cgaaactagc
    21841 attttcgact ccccgattca ctagccatgc atatccccat aaaaagactg tactcatcac
    21901 gatcgatgcc agattttgcc caccttcaaa tactgggaag aaatatccta atgcgctcat
    21961 caacaatgtt gcaaaagcta cgttgcctaa ccagcatgtg agccagtaac cccaaccgct
    22021 gataaaacca gcgaaacggc caaaaccttc ttctgcgtaa ctaaagatcc cgccttttaa
    22081 atctggacgt tttttattga tattattgat cgacaaggag agcatcaaca ttgctgttcc
    22141 tacgagtacc caactgaaaa tagctgggcc gccagccgat ccggagatgt ccgtcataat
    22201 accaaatacg ccacctccaa tcgctgaacc aattactaag gcagcaagtg gaattaaacc
    22261 aattcctttt ttctgttgct ctgtatccat gtaagcatcc tccaaaataa aaccgctttt
    22321 atcaaaaagt ataacaaacc ttttttattt ttacttaatt aataaaaact ttaatagaaa
    22381 tataattcta ccggcttttt tctcattata caagcaaagc gcctagtccc tttccaaatt
    22441 acaccaccaa aaaacttaaa aaagatgcta tactaaaagg aaagaattgg aggatgatcc
    22501 atgaacattt tatatatatc gatttcagga aatacgcgtg cctttgccaa acatctagca
    22561 gaatatgctg aaaaaatgca tgcagaagat cctgtcaatc ctgaagttac tttaaaagaa
    22621 atccatgaaa atagtgattt tacgaaagaa acagaaccat tttttacttt cgttcctact
    22681 tatttagacg gcggaaatgg tttagataac ggtgatacag aaatcttgac cgaaacgatg
    22741 cgtgaatatc tggaacatga agacaatcat aaactttgtc ttggtgtagt cggtagcgga
    22801 aataaaaact tcaataatca gtattgtcta acagccaaac aatatgcaca aacatttggc
    22861 tttcctttct tggcagatta tgaattacgg ggaacaccat ctgatgtgac acgaatttat
    22921 cagattttag cagaaaacaa taaataataa aaaagaagaa gctgaaaaat agatttcagt
    22981 ttcttctttc gtttctattg tttctatcat attaagcttt gacatccatc acaggtgctt
    23041 ttgcttttgc tttacctgtt ttttccaaga caaagttttt tacacgatcc atattggtta
    23101 ccaagacgat catggatgtt tctttgcctg ctgctttgat cgcttctaag tcagcttctg
    23161 ctacaagcgt atcaggtgtc acttgctgcc cttctgttac tttcacatca aatggcgtac
    23221 cgcctaagtc aactgtgttg attcccatat gaagcaagat ttctaaacca tttggcgttg
    23281 tgatcccaat agcgtgtttc gttgggaaga cagagctgac taccccagta actggagaat
    23341 agatatgtcc gttttctggt tctacaaagt agccttcacc catcatcttt tgtgcaaaaa
    23401 ctggatcact tgctttatct aaagaaacaa ctgttccgtc agcaactgat gagaggatag
    23461 tcacactttc agctgaagtt tgaggtacta ctttttcagg cacttcattt actgtggctg
    23521 tttcagtcgc taattcttct ttttctaaac ggtctttagg aataccgaag aagaatgtag
    23581 caacgaagcc accagcataa gctgccaata atccaaggat gtagcctaac catttaccgt
    23641 cagagatcaa tgggatcaaa gcggctcctg aaggtccaat agcgatagcc ccgacatttc
    23701 cgatcattcc gatcactgcc ccgccgatac ctccaccgat acaagcagta ataaatgggc
    23761 gtcctagagg taatgttact ccgtaaatca atggttcgcc gattcctagg atcccgactg
    23821 gtaaagctcc tttgatcatt tctgttaatt ctttatcttt tttgcagcga atccataatg
    23881 ccaatgctgc acccacttgt cctgcaccag ccatcgcaag aattggaagc aatagcgtac
    23941 gaccagtttc atcaatcatt tgcacatgga ttggagtcaa aatttgatgc agtccgaaca
    24001 taaccatcgg caagaataat gtgcctagaa cgaagccggc aaatgctcca ccaacgccaa
    24061 gtacccagtt gatcccaccg accatgccat cagaaatgaa acctgctaaa ggcatgatga
    24121 agaaaatttc aatcagaccg atggcaatca atgaaagagt tggtgtaacg atgatatcta
    24181 ccgcatcagg tactacttta tgcagttttt tctcaacgat tgacaatagc caaacagcga
    24241 agatgacacc taggatccca ccttgtccag ctgcaagagc ttcaccagta aataagtttt
    24301 tcagtggtgc ttccggattc atccctgtca gcatcacaac ggccccgata actccaccaa
    24361 gagttggtgt tgcaccaaaa acttgtgcag cattgatacc tgtatagata actaggtagc
    24421 taaacatccc gtttttcaag atgttcatca catcgatata ttgttgccat gttgctgcat
    24481 caagtgttcc ggctgtgact aagtttgcta aaactgcggc aatccctgcc acgatcccag
    24541 taccgacaaa tgcaggaatc attggcacaa agatattaga aatgtctttt aataccgatt
    24601 tgattttaga tggtttttgt ttcgattttt gtgccgcttt catttcttgt gcccgttcgt
    24661 ttacacggtc ttttccagat gctgatgaat ttgctgtagc tgtacttaca gaagaaagtt
    24721 tttctcctaa tttcacgcct gccaaatcaa ccatttgctg tgctactttg ttcactttcc
    24781 caggtccgat gatgacttga agctgttcat cttctactac accaagcact cctggaatcg
    24841 cttttaattc agagacattt acaagatcat cattgatgat cttcatacgc acacgagtca
    24901 tgcagtggac aatgctttct acattgccca tgccgcctgc ccctttataa atttgttttg
    24961 ccagttcttc caaagtcagt tcgttttttg ccatggtctt ttccccctca taaggtccct
    25021 tttacaaatc cgtttgcttc agctaatttt gcttgagctt cctctttatc actatttgtc
    25081 aaaatcatga cgatagccag cttaacattt tgatctgctt cttcaaagta cttttcagct
    25141 gtttcgtaat cagcttctgt cgcttgcatg atgattcgtt ttgagcgttc gattagtttt
    25201 tcatttgttg gtttgacatc gaccatcaag ttattgaata ctttacctat accaatcata
    25261 ctgatagtag aaatcatatt caagataagt ttttgtgctg ttcctgactt caatcgagta
    25321 gagcctgtca aaaattctgg acctgcatcg acttcgattg ggaaatccgc gtgtttactg
    25381 atttcggctt gtttattgca agaaatcgtt cctgtgacag caccgatcga ttttgcgtaa
    25441 tctaatccac cgatcacata tggtgtacga ccgctagctg cgataccaat aactatatca
    25501 ttttttgtca aattcagctt gattagatct tcttgcccta gctcataaga atcttcggcc
    25561 ccttcgacag ctacagtcat tgcttcttct ccaccagcaa ttagacctat gaccatttcc
    25621 ggttctacac cgaatgtcgg tacgcattca gcagcatcta acacacctag tcttccactt
    25681 gttccggctc ccatataaat cagacgtcca ccttttttaa aggactcaat cgtgttagca
    25741 atcactggtt cgatacttgt cagttctttt tcaaccgcag cggccacttt ctgatcttct
    25801 ttgttcatta gttgaacggc ttgagaaata ctcatctcat ctaatccaaa agtttcttgg
    25861 tttctgcgtt ccgttgttag gttctctaaa ttgattttgc tcatttttat cttccttctt
    25921 ttcttataaa ttgatagttc ataccagctt tgatttggtt gatcaatggt agctcttctt
    25981 tgataacttt agctactaca ttcacttttt catccgctgg caaatcatat ttggttaatt
    26041 ggatctcacc catatagcgc aaatactttt cgttatctaa agtaatagac cctttcatac
    26101 gcgtagctgt atttcttgct gggataggcg gaatctctcg aaaacgtgca tctacgcttc
    26161 gtatgacatc tcttgcatcg tcttgccgat tcgtatgctt ccctaatata tattcgtaaa
    26221 attcttcatc tacaggttcc gtatggagca agactgtctg ttctttttgg aaagaagcaa
    26281 attgctcctg aacgttttct gacagacctg catctccgat gtaaacaata tccgtgttac
    26341 ttgctaatag atctagagcg cctgcaagag gatggatccc tcgatgttct tccaaagttg
    26401 gcaatccttg atatagtggg cctctcaact ctgtatctcc tggtacaaaa ccttggacaa
    26461 ggagaccttg aattttgagc cattgatttt ttttctgata ccattctttg tccagccctg
    26521 tttcgggacg tggataataa ttatgccaag cttcaatctg tgagaaatca gcttctgctt
    26581 ctttcaattc atcgatatct ttaggcgtga tcgtgctagc attcaaactg attttcaatt
    26641 gatgtgacca gtcggcaatc tgctgattgg aaatatgata atccattctt aaacctgtta
    26701 caccaattgc tttcaaaggc gttagatctt ctaatgaaaa acccgctcgt tccaatgcct
    26761 ctcctgaaat atcgaccatc aattctagtt tattcttttt cgcttcgctt cctagttcga
    26821 tcaatcgctt ttgatatgcc gaaacatcat cttctggtat atgcatggaa gtgaaaatac
    26881 cgacaaagcc attggatgcc atttggcgga tatactgttt cttctcttct gacaaagaat
    26941 cgttcataaa tattgaaaag ccaaacatat tatccctctt tttctgtatc cgtcttcatt
    27001 tctatgacta gagtatatat ctaaagaaac aaaatttcaa tacttttatt aaaataatta
    27061 aatttcattt ctaaaggttg agtttatatt atcaaaagaa ttgtcataac ctaaaaaagg
    27121 cactgctaag caaaagcagt gccttgaaat attttattta aataacacaa aaacataatt
    27181 actcataaga aaccaattct gtattatcta ccatgaatgt aaagaacccc tcattaggca
    27241 tcggatgaaa ataagcattg atcactctta tcaaggcatt atggcaaact aacagataga
    27301 cattttcttc gtcttcgatg cattctttca ataaaggaac gatccgtgca tacacatcta
    27361 agactgactc cccatttggg aatcgtacag cgaacgctaa acgtgctttt tgaaagttct
    27421 catctttgct tggcagtcca tcataatccc caaaatccat ttctaccaat cgttcatcaa
    27481 cggtcagcgg caagctgaga cgatcagcaa ctgcttgtgc tgtatctctt gctcgttgaa
    27541 gaggggaatg gatgattttc gtgattggaa caggcaaatc tactaccttt tctgctagtt
    27601 tctgtgcctg catctgtcct ttttcagtca gcggcacatc tgcccgtccg caaactaatc
    27661 cttgtgcgtt ccaagttgtt tctccgtgtc tcgttacata aagcatgtga ttctctcctt
    27721 cgttggcaaa gttcccctta accatacctt gttgttcttg agattacaag ggttagattc
    27781 tctcaagaga aataatctca gtagatactt tatccaggaa ggtttgatca tgttccacta
    27841 gtaacatggc aggtttcacg ttcaagatca gttgttctaa ttgttcttga ttgaagacat
    27901 ccaaataatt caatggttca tcccatgtat atagttcagc tggctgtgat aaagatttag
    27961 ccaattccac ttttttccgt tggcccatac tcatctgctc gatcttgtta tgaaaaacat
    28021 ctctttccat cccaagcttt cggaggttgt tcaaaaatgc ttggtagtct acttggtttt
    28081 tctctgcaaa ttccgccaac gttcctcgat tgtcttcata attttggctt gcataactaa
    28141 tgctcagatg ttttggctgg tatttttctc ctataacctt gccgttgaat gcccccagaa
    28201 gataatggat aatggatgac tttcctgcac cgttaggacc tgaaatcgcc acccgctgat
    28261 gaggctcgat tgtaaaatga attggctcga ataacagatt ttcataccct aattgaagat
    28321 cttctacgct taaaagtcgc ttatggtgag acgcttggct attcatcgtc aaagaatcga
    28381 tatattcgat atcttttaat agtttttctt tctcgctgat ctgggtctcc atccgattca
    28441 cgattgcttt ggatcgtttc atcgtccgtg cagcatcagc acccactgct cctttattca
    28501 ctcgtctaga ttcagtatcg atgaatccga cttgtttctt tgttttatct ccttctcggg
    28561 aacgagacca ttcggctttt tcagctgctg ttttctttag cctactgact tcttttttca
    28621 atttttcatt ttgagccatt tcaaattcat cacgaagttt tttctgttct tcatagatag
    28681 agaaattccc ttgataaagt tccagttgac ttttttcgat tgctaaaaca tggtccacta
    28741 cttcatcgat aaatccccgg tcatggctga ccacgatgaa gccttgtttt ttctttttca
    28801 aataagccgc tacttgtttt ctaccagaga tatccaaatg attcgttggt tcatcgatta
    28861 acgggaaatg agtgtcatcc acaaataaaa gtgccagtag gacttttgtc ttctctcccc
    28921 ccgatagtgt gctgaattct ctccataaga tttcaggatc tgtttgcatc aattggagct
    28981 ctctttcgat ttcccatatc tcaaaatccg taatatcatt taacacgtaa taggttaaac
    29041 gttctttatc ttttgtctgt tgcgggaaat aggcaaattc ttgctgatgg attacttgcc
    29101 cttgataagg tagtttgttt tgtagaatat tcagtaaagt tgtctttcct cgaccgtttc
    29161 gtccgataag tcctagtttc cattgtgtgt caaaatttag atttgcttgt tcaaataata
    29221 atgtgccttg gctgtcgtag ccgaatgtca gattttttat ttcgatttta gacattttcc
    29281 atcacctcgt aaaaaaagac cagtcctatt ttcagaactg gctaaagagg atgcaagggt
    29341 tggatacaca caaaaagacc catacatcga aaaaaccaag ccaatcccga aaatctgcac
    29401 actgcttcct tgtctccaca aggtacagtc tgaatgcagc tttcatcaat cgacttaatt
    29461 tttcaatgca cggatccctc actttgtcct atatttgaaa ttacgatagc ataaagaaaa
    29521 tgattttgtc aactacttcg ggaggatggt gaaaaatctg ctaagtgtct gtcctaagat
    29581 ttttgttttt tctaatgttt gcctgtgttc cattgcttct tctaaaccta ttggacccaa
    29641 atgaatactt aagacaattg ggagaaaatc agaaagtcct tctagctctt ggtctctact
    29701 tccgcaaata gcgattattg gttttcgata tttttttgca agcactgcta caccgtatgg
    29761 aacttttccg tggatcgttt gctgatcgat ccgcccttct cctgtaatga tgacatctgc
    29821 ttgttcgatc tttttttcca atccagtgat ttggctgact aaatcgaaac cagaaaccat
    29881 cttcgctccc aacaaaaaaa gggctccacc aataccgcct gctgctccac ttcctggaat
    29941 atcatctaaa tccacctccc agaaatcttt tatttgctga gcaatctttc ctgcttgttt
    30001 atctaagaaa gctagcgtcg tatctattcc tcctttttgt cttccaaatt gccaagcagc
    30061 tccttgttga cctgtatatg gattggtaac atctgcagcg ataatcaatt ttactttaga
    30121 aacaagaacg tttcttcgat caaaatgaag ttttttagta gataataaag gatttccttc
    30181 tgtgtaccct tctaaagaag cacccaagga ttggagtaat cctagaccac catcgctaca
    30241 cccgcttcct cctaaagtga caataatttg ttctacttct tgaagcagtg catctttaat
    30301 aagttctcct aaggcataac tggaagcaag tcggatagtt tgatccgttg gtttatcaag
    30361 tagatctaac cccaatgctt gtgcagattc gatgactgcg gtgttttttc cttgccaagt
    30421 tgtcaataaa tagctgattt ttcgctgacg gaataagaga tccatcccat caatggtacg
    30481 ccatgttccc ctgagcgcgt aatagattgc ttctgcagta ttttctccgc catctgcaat
    30541 cggcacattg atttttcttc ctttacgatc ttcccagcca tttagaactg cctgatttag
    30601 ttcaaatgaa gaagcacttc ctttaaatga atcaattgcc gccaaaatat ccatctgtat
    30661 ccctcacttt cttcttaagt aagacacttt ttttcatttt tttcaaacaa aacaatgcta
    30721 ttttcttcca tttttctata tactaaaagg gaactcattg aataaaggag agaaaaaaca
    30781 tgaaaatcgc aatagctggg gccggagcaa tgggcagccg aatcggattg atgctacatc
    30841 aaagcggaaa tgaggtcctc ttgatcgatc gttggcctgc tcacattgaa gccattcgta
    30901 caaatgggtt gattgctgac tttaacggta aagaagtggt cgcaaaactg ccaatctatt
    30961 caccagaaga aatcatcgaa agcaacgaac acgtggactt gatcgtagca ttaacaaaag
    31021 ccaatcaatt agatgatatg ttttgttcga tccaatccat tattactgac aatacttatg
    31081 ttttgtgttt actaaatgga ttaggtcatg aagatgtact ggaaaaatat gtgccaaaga
    31141 aaaatatctt atttgggatc acgatgtgga cagctggtct agctggtccc ggaaaagtca
    31201 cattgttagg tgatggagaa atcgaactag agaacttgga accagaaggc gaagcattta
    31261 caaaaaaagt tgtagaagtc tttcaagaag caaatttaaa tccgatctat agccataacg
    31321 ttcgttattc catttggcga aaagcttgtg taaatggaac attgaatggt ttatgcacga
    31381 ttttggattg taatattgct gaactaggcg cgcaaaaagc ggcagagagc atggttcgaa
    31441 caatcgtatc tgaatttgct tctatcgcag caaaagaagg aatcatacta gatcaagaag
    31501 aagtgtacca acatattgct tctacttatg atcctgacaa catcgggttg cattacccat
    31561 ctatgtacca agacctgatc aaaaaccatc gtttgactga aatcgactac atcaatggtg
    31621 ccatttggcg aaaaggacaa aaatatgata ttgctacacc atattgtgcc tttttgaccc
    31681 aattagtcca tgcaaaagaa ggaatccttg gcgcagaata aaaggctctc tgatgagaat
    31741 cagctgaatc agcagctggt tctctttttt taagcccaat aaaagatcaa aaagaaaaca
    31801 caactctcat gatgccataa gaattgtgct tgtttgtttc agtacataat ctcttcaaaa
    31861 tgtaggtttt ttatttgttt tcaacagagg agaggtcata ttcgtattgc tcataaatag
    31921 tggaatcgtt agtgataaat cgttttgccc aattttctgc atcataaaat tccaatagct
    31981 ctgataggat tggcttaaat ggtgtatgca gaaattccgg taattcatct aaatcacgtt
    32041 ctcgaagcaa aaaaatattt tcaggacgat aaaaatgata atgagcaatc gcttgattat
    32101 ccgtcactag tttcttttga aaatacatgg attcaaatgt ccgcaaagtc actccttgct
    32161 gaccctcccg caacagttcc agaatcccgc gcgattcccc tgtttttttc aggtactctt
    32221 cataagtaag atatccaggt tgttcattcc ctcgatgtgg aagaatgaaa tagttggtcg
    32281 taacatctct ttttataaat tcctgcttat agctttctgc tcgttctttt ctcccattat
    32341 tcgttgcacc aaaaaataga tccgtctttg gttcgctaga agaaaaattc atatgtttcg
    32401 aataaaatga actattatgt ttcagcccaa gttcttttgc ttccaaaaaa tcaaaatgat
    32461 aaatctcatc gattgccggt tcatcttgtg cctgcttcag catcgcctcg tgttctgctt
    32521 tgaagtgatt ccaaaaaaat aacacaattt ttgcattggt aaatgggcgc acgcgtcgag
    32581 ccatctccat atcaaatcca taatctaaaa aaacgatcag ctgataattt gccaactgtt
    32641 gtctagctga tttaatgaat tccgactgta gtaaatcttt tccggaccaa acatctaaag
    32701 agcggatgga aggcaaaaaa taaagtgatt tattttttgc aactagcagt acgtcatttt
    32761 tgttcatctt ttccgcctca ctttctctgt cactttttcc tatgatagcc tgtttaaata
    32821 gtaaaaagcc agtaaaacgt ttcctatatt tgtatgaaaa tttaacattt gtatgaaaat
    32881 atgatgaaat aaatcattct tctattaaaa ttcgcctaaa agttttctga atagttgtaa
    32941 ttgtctgaaa atttgttatc attagtcatt gttaaatatt gctatttatt cttaatataa
    33001 attttgattg tgaatttaaa agaaagaggt catttatgga agataaaaaa ttgaaaaaac
    33061 aacttagctc cagacatatc accatgttag ctttaggtgg agcaatcggt gcaggtctat
    33121 ttaaaggaag tggcgaagcg attgggatcg ccggcccttc tgtattgatt gcttttttga
    33181 ttggtgggct gattttatat atcgtgatga aaggtctggg aaaaatcgtt ttaagcggtg
    33241 gcgacacgca tcacggatta tctggtttga tacgccctta tctaggtgct cattctgctg
    33301 attttactga ttgggtctac tggtctatgt ggattatcaa tatcatcgct gaagctgttg
    33361 cagctgcttc ctttttgcag ttgtggttcc cgcacattcc agcctgggta tttgttttta
    33421 tgttggctgt tttaactacg atcatcaatc tttattcggt acggttattc gcagaaacag
    33481 aatattggct ggcttttgct aaaatcagtg tcattatctt actgatcatt tttgctactt
    33541 atcttgtcgg tcagcaaatg ttgggcacag gcgttttccc tacccttcag caattgactg
    33601 accatggtgg gtttactcct catggtatga agggaatcat cagttctttg cttgtagtta
    33661 tctattctta cggcggttct gaactgattg ctatcacggt aagcgaagca gatgatccta
    33721 aacgtgcgat tcctaaagca atcaaaggtg tcatgggaag aatcatttcc ttttacatca
    33781 ttcctttgtt tttgcttttg attctttttc cttggaatac tttagcaggc acgaatgtca
    33841 gtccttttgt gatggtattt gaaaaaatga atatcccatt tgcagcggat atcgtcaatt
    33901 ttgtgattgt ccttgctttg ttctcatcta tcaattcggg tgtgtatgca tcttcaagaa
    33961 ttttgttctt ccgtttgaag gatcgaaaag gttcctctag aaaactagct gttttaaaca
    34021 agcatcaagt accgcaacgt gctgttttat tttgtaccag tgttctttat cttggtgtag
    34081 ctctttctta ttttgtcggt gacaaattat ttggctatct ggcaggttcc ctttcgtata
    34141 cagtattatt gatctggatc attatcagtg cggcatcctt tgtactggca ctaagaaaag
    34201 gaacattatg ggataaagga atcagctttt ttgcattagc tgtcttagga ttgattttcc
    34261 ttggtatcct gttcacgaac tccattgggg taactgtatt gactggcctg ctttacctgt
    34321 tcatttattt cagttatcaa aaaaagaatg atgcgttcgt attgacgaat gaatgaaatc
    34381 gatagaaaat tttattttat ttatgtggaa tagatggagc tattgaagaa aggagttgtg
    34441 acaaaagtct tgttgcaact cctttttccg aataaacagt ctcatgacct cttggtaaac
    34501 ggtgttcaaa aaccctctgt gcaaaataat tgattgttct ccatgctcat gacatgatag
    34561 aagaaaggaa tgaaaaaaag gagtttgttt taaatgaaaa agtattggaa gtttttgttg
    34621 atgatcggtg tttcaacggt agttatgttt ggtatgatgt acttgaatgt ctatgcgctc
    34681 gatcatatct tcttcagtcg tacacgagta ttcatggcgt tgatgatggg tgcagtcatg
    34741 gcagtcatca tgctgttgtt catgtggaaa atgtatgaaa acaaaaagat aaatgttatg
    34801 atcttagccg ctagtcttct tgtttttgcc ggttccttgt ttatggtacg aagccaaact
    34861 actgtcaacg acacagcttg gatgaaggcc atgattcctc atcattctat cgctatcctg
    34921 gcaagtaaac gagctgattt aaaagatcct gaagtaaaaa aattagcgga agaaatcatt
    34981 caggcacaag aagaagagat cgacaaaatg aaaaaaatga tcaaagaaat ggaatgacca
    35041 ttatccgtcc aaataaaaaa agaggatgtt ccagaagtta tcagcttcaa gaaataagaa
    35101 gaagctactt ctggaacgcc gtgaataagg ggttgtgaaa aagctgccct gcatcaagta
    35161 ataagaacag ccaaacaaaa atagcttctc ctatttttcg tttggttagg cttattaccg
    35221 cagatgcaag cttttgaaca ccgtttatta agaggttgta aaatcagcgt tctgacctga
    35281 gtattagaga gacaaatgga aaaatagttc ctcatatttt gccatttttt gagctaatac
    35341 cgagggtcag ctgattgaac accgtttatc gagaggttgt gaaaaagtcg cttagtttcg
    35401 cgtattaaga aaaattttgt gaaatggctt tccacatttt tgtataaatt tggcttaata
    35461 ccgagaaact ggcttttgaa taccgtttat tc
//
LOCUS       DAIGUC010000028        35335 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.028, whole genome shotgun sequence.
ACCESSION   DAIGUC010000028 DAIGUC010000000
VERSION     DAIGUC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.028"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..380)
                     /locus_tag="NOB46_001451"
     CDS             complement(<1..380)
                     /locus_tag="NOB46_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HCI1058391.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTV"
     gene            complement(494..1078)
                     /locus_tag="NOB46_001452"
     CDS             complement(494..1078)
                     /locus_tag="NOB46_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HCI1058392.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(1205..1636)
                     /locus_tag="NOB46_001453"
     CDS             complement(1205..1636)
                     /locus_tag="NOB46_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI1058393.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(1654..1974)
                     /locus_tag="NOB46_001454"
     CDS             complement(1654..1974)
                     /locus_tag="NOB46_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1058394.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENK"
     gene            2274..2414
                     /locus_tag="NOB46_001455"
     CDS             2274..2414
                     /locus_tag="NOB46_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058395.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            2712..2969
                     /locus_tag="NOB46_001456"
     CDS             2712..2969
                     /locus_tag="NOB46_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HCI1058396.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(2940..3248)
                     /locus_tag="NOB46_001457"
     CDS             complement(2940..3248)
                     /locus_tag="NOB46_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058397.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            3326..4072
                     /locus_tag="NOB46_001458"
     CDS             3326..4072
                     /locus_tag="NOB46_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HCI1058398.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            4087..4290
                     /locus_tag="NOB46_001459"
     CDS             4087..4290
                     /locus_tag="NOB46_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058399.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            4306..4644
                     /locus_tag="NOB46_001460"
     CDS             4306..4644
                     /locus_tag="NOB46_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HCI1058400.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            4631..4801
                     /locus_tag="NOB46_001461"
     CDS             4631..4801
                     /locus_tag="NOB46_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058401.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(4899..5564)
                     /locus_tag="NOB46_001462"
     CDS             complement(4899..5564)
                     /locus_tag="NOB46_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058402.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            5619..6317
                     /locus_tag="NOB46_001463"
     CDS             5619..6317
                     /locus_tag="NOB46_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HCI1058403.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFSEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDTVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            6495..6835
                     /locus_tag="NOB46_001464"
                     /pseudo
     CDS             6495..6835
                     /locus_tag="NOB46_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6828..7499
                     /locus_tag="NOB46_001465"
     CDS             6828..7499
                     /locus_tag="NOB46_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI1058404.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            7505..8191
                     /locus_tag="NOB46_001466"
     CDS             7505..8191
                     /locus_tag="NOB46_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058405.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFKNKYQIKGIKLSH
                     ETIKKLRIGG"
     gene            8194..9024
                     /locus_tag="NOB46_001467"
     CDS             8194..9024
                     /locus_tag="NOB46_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI1058406.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLGSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSNEHLRLAKKLQSNLTEDFPKEMTKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            9041..9892
                     /locus_tag="NOB46_001468"
     CDS             9041..9892
                     /locus_tag="NOB46_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1058407.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            9889..10248
                     /locus_tag="NOB46_001469"
     CDS             9889..10248
                     /locus_tag="NOB46_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI1058408.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVIDVKGMQTKDFKIKAKLFCHKYQV
                     PLILAKKYRNTFKEERF"
     gene            10263..10424
                     /locus_tag="NOB46_001470"
     CDS             10263..10424
                     /locus_tag="NOB46_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI1058409.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIVNL
                     RREIRRLEE"
     gene            10427..10726
                     /locus_tag="NOB46_001471"
     CDS             10427..10726
                     /locus_tag="NOB46_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058410.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVAEVQKIGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            10726..11043
                     /locus_tag="NOB46_001472"
     CDS             10726..11043
                     /locus_tag="NOB46_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCI1058411.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLYQDRFKFVEKYREILDEYME
                     EAE"
     gene            11040..11243
                     /locus_tag="NOB46_001473"
     CDS             11040..11243
                     /locus_tag="NOB46_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HCI1058412.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            11240..11533
                     /locus_tag="NOB46_001474"
     CDS             11240..11533
                     /locus_tag="NOB46_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058413.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVIKS"
     gene            11563..12003
                     /locus_tag="NOB46_001475"
     CDS             11563..12003
                     /locus_tag="NOB46_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1058414.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            12078..12545
                     /locus_tag="NOB46_001476"
     CDS             12078..12545
                     /locus_tag="NOB46_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HCI1058415.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(12945..13298)
                     /locus_tag="NOB46_001477"
     CDS             complement(12945..13298)
                     /locus_tag="NOB46_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058416.1"
                     /translation="MAKIDDYRSDMIEYIELFAKNSNNNIIIQTGGATICGTPIDFDA
                     EVKVNPLIDAMMDSFAEFRSKKIDDIEKDDEQSLVVKSIFLKDVTIIGERTTNIPFLV
                     VFADQISAISLGNLE"
     gene            14016..14087
                     /locus_tag="NOB46_001478"
     tRNA            14016..14087
                     /locus_tag="NOB46_001478"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14049..14051,aa:Lys,seq:ttt)
     gene            14227..14394
                     /locus_tag="NOB46_001479"
     CDS             14227..14394
                     /locus_tag="NOB46_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058417.1"
                     /translation="MYRPQYLEQKHEVITVQNGNGEIVRKYRRPIKSNTYKRKESNEV
                     IPLYGKRIAKY"
     gene            14420..14764
                     /locus_tag="NOB46_001480"
     CDS             14420..14764
                     /locus_tag="NOB46_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI1058418.1"
                     /translation="MTEEFYRWLLQLIREDCLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            14769..15050
                     /locus_tag="NOB46_001481"
     CDS             14769..15050
                     /locus_tag="NOB46_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058419.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNIFGYSIEEINYYIDFAEAFIPMVR"
     gene            15153..15467
                     /locus_tag="NOB46_001482"
     CDS             15153..15467
                     /locus_tag="NOB46_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HCI1058420.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            15445..17139
                     /locus_tag="NOB46_001483"
     CDS             15445..17139
                     /locus_tag="NOB46_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI1058421.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            17159..18337
                     /locus_tag="NOB46_001484"
     CDS             17159..18337
                     /locus_tag="NOB46_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI1058422.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKDFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            18300..18986
                     /locus_tag="NOB46_001485"
     CDS             18300..18986
                     /locus_tag="NOB46_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HCI1058423.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            18986..20146
                     /locus_tag="NOB46_001486"
     CDS             18986..20146
                     /locus_tag="NOB46_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI1058424.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            20156..21031
                     /locus_tag="NOB46_001487"
     CDS             20156..21031
                     /locus_tag="NOB46_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058425.1"
                     /translation="MKYILCQLAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            21028..21339
                     /locus_tag="NOB46_001488"
     CDS             21028..21339
                     /locus_tag="NOB46_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058426.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            21329..21682
                     /locus_tag="NOB46_001489"
     CDS             21329..21682
                     /locus_tag="NOB46_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI1058427.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            21672..22073
                     /locus_tag="NOB46_001490"
     CDS             21672..22073
                     /locus_tag="NOB46_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058428.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            22066..22470
                     /locus_tag="NOB46_001491"
     CDS             22066..22470
                     /locus_tag="NOB46_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058429.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            22482..23090
                     /locus_tag="NOB46_001492"
     CDS             22482..23090
                     /locus_tag="NOB46_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1058430.1"
                     /translation="MAKTKTVVTTFDNISIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELEAKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            23110..23472
                     /locus_tag="NOB46_001493"
     CDS             23110..23472
                     /locus_tag="NOB46_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058431.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            23475..23657
                     /locus_tag="NOB46_001494"
     CDS             23475..23657
                     /locus_tag="NOB46_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058432.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            23674..27093
                     /locus_tag="NOB46_001495"
     CDS             23674..27093
                     /locus_tag="NOB46_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI1058433.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     VTAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFIDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            27144..27881
                     /locus_tag="NOB46_001496"
     CDS             27144..27881
                     /locus_tag="NOB46_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1058434.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFTLNDYVFSFEGLVVGTDIVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            27891..30182
                     /locus_tag="NOB46_001497"
     CDS             27891..30182
                     /locus_tag="NOB46_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI1058435.1"
                     /translation="MIDNLLTIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREVA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNVGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            30206..32383
                     /locus_tag="NOB46_001498"
     CDS             30206..32383
                     /locus_tag="NOB46_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058436.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPYLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAETKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGNPNLMANINADSFS
                     QGSGALSVVDDGDEVVITLDPNHKLEVLKPKSQPALLTGKTYTVSVEIMLEGDFTGDP
                     SKIGLRYIKMPNWVSELYTRNTLTATKGVWQKLTGTVKITAASDNAESWLIMLQNKDA
                     NNSLSGKLRLRHAKLEEGSTATPYQPNLLAEPYNMCREYPNENIADPKVKFPIKSGDH
                     QIYQGYMEEDLMIGQTYTITLKGTKPASQTFVAYNHWTVRLGELKPVDGLTDVWSLTF
                     TPTNVAAMPKLFRVYQYPQSTVGACQIDWLKIEKGNTRTPNISEYKYRGTGMRDSNNP
                     KDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKDA
                     QTKANANATAIDERINDTATTAFYGAQGEVSNKTKVAEYGVGTGYTTTAVGETHFERQ
                     SNGYVKCLKAGKYSISAQIRVQLGGKYASWLYTDLYKDGTSVDNLVSYGVDALQNRFA
                     ASGNIVTDLEVNDVLNMRTEIGVADGILQFTSCRTLVLTRLSD"
     gene            32461..32703
                     /locus_tag="NOB46_001499"
     CDS             32461..32703
                     /locus_tag="NOB46_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HCI1058437.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYELLREKAESAKDRADQAYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGVTIIGYFLTKL"
     gene            32719..32916
                     /locus_tag="NOB46_001500"
     CDS             32719..32916
                     /locus_tag="NOB46_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI1058438.1"
                     /translation="MILPDKYYQVIKWAVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            32927..33946
                     /locus_tag="NOB46_001501"
     CDS             32927..33946
                     /locus_tag="NOB46_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI1058439.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHNKATFEKNYKAYVELARDSAKKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYGTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            complement(33986..35325)
                     /locus_tag="NOB46_001502"
     CDS             complement(join(33986..34884,34884..35325))
                     /locus_tag="NOB46_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HCI1058440.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT        12450 a         5455 c         7104 g        10326 t
ORIGIN      
        1 ataacggtgg attttacatg gtctttcgca tacttattta aaaagcgttg atatccaact
       61 ctatctaaat cagaaatcaa taccgctggc atatatttct ttatgttcat taacgtatct
      121 tcgtattttc tataagtgat aggagatact gttccttctt tataaagttg catccaatcc
      181 tcaaagtaat ctgataataa tagatttttg cgatcccctt taaggccttt gttcaagtta
      241 tattctaatt cgttggcggc atcttttgct tcgccttttg tcttaaatcc tgattttctt
      301 atcttcgtgt attttccgtc atcttttttg tatgaaattt cgtattgcca actatttcca
      361 cgtttgacta atcttgccat aattgaatct actctctttc tctgatacaa taggcactat
      421 aaagaagcct actgtatagg tttgtttttc ttagaacacg cttgctttgg acggtgggcg
      481 tgttttttat ttattataca gttgctttaa aaatagctgc tttttcaaat gatactaaag
      541 gagagaagtg gatttctatt tctccctttt ggtttaacgt gaaatgagca gttacatcca
      601 tttgttttcc tggagcaaca gatcccattg tattttcgtt ggcatatgtc tctgattttt
      661 tgtcatctgg tccatatact tccacatctg tacctacagg gatatctgaa tcgccatcat
      721 tttttacggt ataagtaatt tttactactt gtgcaggttg gttttcttca aattgatttc
      781 tttcatcagt tagttctaca ctatttagtg tatattcagc atcaccaact tttacagtgt
      841 caccaatctt atagaaggta tcgctttttt cttctttaga agatgaagca gaggttgaag
      901 atttagttac tttttcgcca ccattatcac ttgctttatt actatctgat ccaccattta
      961 aagcagaacc aataattata attaaaatta ctgctaatac ccaaaaccat acttttttgt
     1021 aaaaaggttt actaacttta tacatttttc cgtcttgacc cataactttt tttgccattt
     1081 aaatattcct cacttcttgt tataatatat ttgcgatctc agaaatgagg tatgagtccg
     1141 tgtgccagca cgggcttttt taatgttttg ctgaaatcgg tttttttaat aattcttgat
     1201 gtattcatac atattgcctt gcgtaagaat attttttctt aaaatagcat tggcagacag
     1261 cataacaagt gtatctgagc ttattctgaa tagaataata ctccataaat ttttcgagat
     1321 taaactgaga ttcatcagtc agttcgttct caatatagat atttaataaa attagaatag
     1381 ctattttatc tgcttctgtt tcaaattttg agtgaaaagt tgtagaagta tcgtacaaaa
     1441 ctgaaaattc aaaatgagag gcgctgaaat gtgcaagttc atgagataaa tgaaaggctt
     1501 ctgcagtttc accgtataga ttttcattca aaaaaatgat tctgggtttt ggatagtaga
     1561 aaccaggctc tttcatttcc atataaacta ctttcaaatt gtattcgctc aacatttctt
     1621 tcaatttcaa atacatataa accatcactc caactatttg ttttcttcta aagctttagc
     1681 aattgcaatc gctttacgca ttgtctcctt agatatttct tttccgtcaa aagaaaatac
     1741 agtatcgttt tctgataaat ccacatgttt aggggtttct ctttcttctc tacctagaag
     1801 gtagtctaca gagactccaa agtaatcagc taaccgagct aactcaatag aattaggagt
     1861 ttgtcttttc caacttccta aatatccatt cgaatacccg aaattcattt cgagctgtct
     1921 aatggataat cctttttctt ttgctaactc ctttattatt tcgtaagtat tcattgataa
     1981 atcaaccttt ctgaatgctt acaaaaaaag tttagataaa taatgtaaaa atagttgact
     2041 tatatacatt attaatctat actatgtttt gtaaacaagt ttaacaacta aaaagacaac
     2101 aaaaaatact attgattaat aaatgccaac cgccaagaaa gctttttaaa tcaaagttta
     2161 tatgtcttat ttaactatgc atttagtata gattattaat ctaataaagt caacgcagtt
     2221 ttttaaaaag ttgttaaatt tgtttacgaa tataaaagaa aggagagaag aatatggaaa
     2281 aaacagtctc ggcaaaaatc gaagatttga aattagacat actgaaacaa gcaaaagtgg
     2341 cgatggaaca cgcggtagat aaagaagact ctgccatggt tgcagccata gcagagattt
     2401 tagctcacgt ttagtcatcg tttttacggt cttctggaag ctgaccatag ataacagcat
     2461 aatgaatatc taaataagct tgaacaattt cttttggcga aattgattcg cctttagtag
     2521 atacttgtga ttcgtgattt agccatgcaa caactaaatc cgcagcgatt tcaaacggcg
     2581 ttacactttg tgtcagttgc cataaagaat ttcacaatat gtatggtcgt ggtaataata
     2641 ccaaagagca atttgaggaa tttatggaaa ttaaaaaata caaaaaatca tttattaaag
     2701 gaggctaaac aatgaacaag gaaatgagcc aaacaatcaa ggtacaaaaa atgatagatg
     2761 atctaacaca tggaattgat agccaagccg ataaaatcat caaggaattg caaggacaaa
     2821 aagttaagga tgcaaaaatg cttctcaaga ctatcaactt tgaaatgaat ccaacaaaaa
     2881 gaaagctcgc cgatgtgttg gaagaaaagt tggcttccgc tatcaacgag caagaattac
     2941 tatttgaaac cgatactttt aacagctgat gttttataga tgacagtttc atccgaatct
     3001 atatcatcgc cgagagaaaa gaatgttgct tttgacaaaa agccgataag acctacaagc
     3061 ggtcttgatg ttgcaagagt agatacccca atatcacctt gcaaggtatt cacgtaaatt
     3121 tgagaagaat agaacattcc atctttttct tcgatatttg acgcatcatc gtatccaacg
     3181 accaaagtat cggcaaatat tttgattttt tctccatcaa gcatagtaat tacaaattct
     3241 ggtttcataa attttcacct ccttaacaat tatttcagcc tgtcacactg ataaggaaat
     3301 tataccaaag aaaggaatga gaaatatgaa tacaccacaa atttttaatt tcgagcaaaa
     3361 cgaagttcga actattttag taaatgatga accatatttt gtaggaaaag atgtagcaga
     3421 cgttctagga tattcgaatc cgcaaaaagc tattcgagat catgtggact tggaggataa
     3481 gacgcagaac gattcgttca ccgtcaatgg aacagcagtt gttttgatta acgagtcagg
     3541 cctttacagt ttaatcttaa aatcaaaact tccctctgcc aaaaaattta aacgttgggt
     3601 aacgagtgaa gtccttccaa caattagaaa aacaggtagc tattcaaacg tacctcaaag
     3661 ttttgcacaa gcattgcgtt tagcagcgga tttagaagaa aagaaccaat tactcgaaca
     3721 acaaattgcc gagtacgaac caaagattag ctacttagat acgattcttt catcgacaga
     3781 tacggtagct acttctcaaa ttgcagctga ttacggaatg tcggcaattg ctctaaacaa
     3841 attgctaaac gagttaggtg ttcagcataa agttagcgga caatggatac tttaccgaaa
     3901 acatatgaac caaggataca caaaatcgca cacaagtgag ataccgaaag ccgatggcgg
     3961 cactaaagtt gtaatgaata ccaaatggac acagaaaggg cgagtgttta tttacaactt
     4021 attaatcgca gagggctatt accctcaaat ggatttagag gaaattggtt agaaaggagt
     4081 tttagtatga ctgacattgc agaaatcact caacgagata gagaaaaaat caaagaatat
     4141 gtcgaaagtt cgaagttctt aacttacacc atgcttgctg aaagatttgg aattagcaaa
     4201 agctacttat ctttaatttt aaacggtaaa aagacttctg cagaagcaaa tagaatcata
     4261 gattcgatta ttactatgta cgaattgtaa agggaggaac agctaatgca atatctagaa
     4321 gcgaaaatcc cagttccaga aggctatgta attatctccc aagtggatta tgaggagtta
     4381 aaaaaagctg atgatactgg tagatggatg acgttgccag aagtgctaga acggattaac
     4441 agaaaatatg attggtttac ttctagagtt ttaaagaacc caagatatag aaatattatc
     4501 gatatcgaaa aaaataaaaa tggatttgtc tattatccag ttgaaggaag agacacatat
     4561 ctatttttaa gaagtaaaac acttgaattt ttagaaacaa atttttcgga aatcttaagg
     4621 aggcaagcgg atgggaaaat ttaatagagc gctagtattc agcgcaccgc taatcatcta
     4681 cgctttagga ctttggggaa gcagacaagc gttgatagga acgattgttt acatggtttg
     4741 gatttttatg gggctggatg aagctgagta caaaacaaaa aagccagtcg ggagggactg
     4801 actaatgaaa aaaagtttaa tgactataaa cgaaaaacaa ttgaaagaaa attttaatga
     4861 tctcatcaaa gaatttgtaa aagaaactgg agaatttcct aatcaaattc atctagttgc
     4921 ggaggggcat agccagtatc aagctgtgaa atttgagatg aagaaacaaa tctattgaat
     4981 ttagcagtac ctctacttgt aagaacattt attgtaatgt ttttttcgac taaagattca
     5041 tcgtatctaa aaaccaacgt agtaattttt gactcatacg gtggaatggt aataggtaat
     5101 gacaacggag gaaattttga tagatcagca ccttttttta aagatttacc agaatacgca
     5161 cgtataccat gtggaagttc gtcatacatt gattttaccg ttacagaata attatcacca
     5221 atcattgtaa aagcatttaa atgatcagga attccagaaa tcgaaaactc aataattgta
     5281 acaggtaaag aactgttatt tgttaacaat acagaatcta taatcctgaa tttattttga
     5341 tggtaaacat ctggtttgga atcactttct ctatctatca accattcttc gcattcagcg
     5401 aagaaatcca attttaaatt aaattttttg ttttttctat ctgtatagga gatataaaaa
     5461 gcaaatgttg aaaatactag agacgtaata ggcaaaataa aatctttaat ggttttaaca
     5521 atgttattcc agtcaaattg tttaataaag tcaataagac tcaatttata ccaccaccat
     5581 tttttatcta cattatatca aagaggagag aagaaataat gcaagaatta gtaattttga
     5641 aaaataaaga agctgtgact acgagtttgc aagttgcaga aagttttgag aaaaagcatc
     5701 aacatgtttt aagagatatt gatgcactga aaaaagatgt gtccaatttt ggacagatgt
     5761 tttctgaagg taatgaacca gattcatacg gcagaaatcg acgagttttc ttcattagta
     5821 gagatggttt tttcttgttg gctatgggtt ttacaggaaa gaaagctatt tacttcaaac
     5881 aaaaatacat tgaagcattc aacgaaatgg aagatgttat tcgcaagaat actgttcctc
     5941 aaacaattga agatatgatg atctaccaac tagaagaaat gaaagatgtt aaaaaagatg
     6001 tttccatgct taaagatact atgcgaatta gtgggcaaca agagtttgaa attaaacaaa
     6061 aaggaaatat aaaagttatg gaagttctag ggggtaaaga aagccgagct tatgaagaaa
     6121 tcagcaaaaa agtattctca aaattttggt ctgaatttaa acgtaccttt tcaatcccaa
     6181 gatatggcga gttacctcgt aagagattcg atgatactgt ttcatttatt gaaatgtggt
     6241 taccagaaac tgcgatccgc atggaaatcg atcaactgaa cagacaacaa agacttttcg
     6301 gtgatgaaaa tgaatagagc tgaagcgcta agaatcggga cggtaattgc taatcgctgg
     6361 tggagacaca ataaaccaat catcctaagc caacaacata ttgacaagca aaaagcatgg
     6421 caacaaataa aaaagtgact ccgccggcaa gcaaagagtc acaaagaaaa cacatcataa
     6481 ggagatttta gcatatggaa aaagaacttt ccactctaga tcaatatttg actgatccta
     6541 gttggggcaa atcgaatatc aaggaaacaa ataatcgaaa aatcagacga aatcttttga
     6601 cggatgaaga actagcatgt gatcaagacg atttgggaaa ttttgtgagt atttgggatc
     6661 atgtctatct tatccattta tcgaggaagt ccaaaaacct gaatatatct atgtcatcga
     6721 agatggcttg attgatgcgc tagaagagta tgacagagat aacttgattg atatctctta
     6781 ttacggatca ggtaagaaat acattgctga aatggaggca gaatttgatg agtgaaaaca
     6841 aagggacaac gacttttgaa aaacttttta gtcgcaagtt aaataaaata ctcaagaaaa
     6901 aaggaaattt tgattattta tcttgggctc acgcatggga gattatgaaa aagaatgatc
     6961 cacaggcaac ggtaactatt aatgagtata aacactacag agttgtttct ggaactcatc
     7021 aagactttct tgttgaggaa tataaacctt ttcttatgga tgaaactggg acttatgtat
     7081 ctgtctcagt aacggttaaa ggacacacgg aaaccgaatt atttcctgtt ttagattatc
     7141 gaaaccaacc agttgttaaa ccaaatgcaa tgcaaatcaa taactcattg aagcgatgct
     7201 ttgtgaaagc attggctcta cacggactgg gattatatgt atttcaaggg gaagatattc
     7261 caacaccacc tagaatcgat acgaagaaat taaacatgct agagacgatt ctagaagctt
     7321 tcaatgagca gatgggtaaa gatatgacca aaaccttaat cgaatatgtt aatgagcaga
     7381 cagataaatt agggctctta gctgataacg ttgaaactat tgaacagtta agctatgagc
     7441 aatgtgcctt gatggagcga gcaatagcag ctaagagaaa agaattagat aagaagtgat
     7501 atgagtgttt aaaccattaa tcgattcata ttcagcggtt ctgaaaaagt tcaaaggaaa
     7561 agacataggt gcaacgatca atgaagaagt gaacattgat cgactaaaga cgatgtatga
     7621 cggctacgat ggcgatcgag tcattgaaat tcgttttatt gatcctagac gtttcactgt
     7681 acagcaacga aacttcatct atgcgctcat aggcgatatt ttcatcgata caggcatgcc
     7741 aacggacttc tggaaggaat tcttctactt ccgtttcgaa ggtgtcacag ggcgcaaaat
     7801 aagcctcaaa gacgaatcga atacaaccgt gagtgatgct aacgtcttag caaatatcat
     7861 cctagatttt atctttgaac atcatattcc tttcaaagaa ggctatgaga ttttaccagc
     7921 gaatcaagag tattacttct acaaatgcat tacaaaaaga gtctgctgca tctgtggcaa
     7981 aacaggagct gatattgatc actttgacaa agctttagga agacgaaagc gcaaagaagt
     8041 tgatcattca gagtacacat ttgcagcact ctgcagaatc catcacacag agaaacacaa
     8101 aataggtgtg accaatttca aaaataagta tcaaatcaaa ggaatcaagt taagtcatga
     8161 aacgattaaa aagttaagga taggaggata aatttggctg agataagttg gatcaaactt
     8221 aaaactacta tgtttgacga tgaaaaaata cgattaattc aagctgttcc tgagtcggat
     8281 gccatcatcg ttatatggat tcgattacta gttttagcag gaaagactaa cgacgatggt
     8341 ctaatataca tccagaggaa catgccttat accgaagaaa tgcttgctac attgtttggc
     8401 aaaaacgtaa atacggttcg cttagcacta accacattgg caaatttcaa catgattgat
     8461 ctaggcagtg atggactaat tgccatcagt aattgggaaa aacatcaaaa tatcgagggg
     8521 atggataaag taaggctaaa aaatgctgaa agaaaccgta aatacagaga aaggaagaga
     8581 caggaacgtc tcaaattgga aaatgacgtt agcgtgacgt cacgtgacgg tacagataaa
     8641 gatatagaag aagataaaga tatagataaa gaagaaaaga aaggtaagta ttctaacgaa
     8701 cacttacgcc ttgctaaaaa gttgcaaagt aatttaactg aagattttcc aaaagaaatg
     8761 actaaagtag atatcgaaaa atgggcagac acaatcaggt tgatggaaga aagagataaa
     8821 gcatctatag aagcgattga gtatgtgatc aattggctac ctacaaatga attttggttt
     8881 ggaaatatta gaagtgctaa gaaattgaga gaaaaatttg agaagctcaa attcgaaatc
     8941 aaagcagata agaagaatca taaaaagcaa agtcaaaaac tacagtacag caatcctagt
     9001 gaatatgacg acttgccaat ttaaaaagga gatgcatcac atggaaagcc tagcaaatgc
     9061 tatggagaag ctaataagaa gagtattagt gcaaagcgga aaatgtccag aatgtagcga
     9121 acctttgtat agttggcgag ctaaaaataa ggatggttca gaacgttgta aaccaacatg
     9181 catgagttgt ggttataaag cgttacgtgt gaaagaggat atacagaccg aacggatata
     9241 taacgacagc ttaaaagcac gagcattgag tttttttcaa aatggttcgg tattaacaga
     9301 taaaactttg tttaaatgca aaatggagaa ttatcacgta gtggaccaag aaacgaaaat
     9361 tgctttagaa agagctaaaa gctttgtaaa tgatgtccta ctgaaccatc ctgcacattt
     9421 cattctatca gggaaatcag gaagcggaaa aagccacttg tcaatggcga cagcttggga
     9481 aatacttgag cgctcaaatt atgacaagaa aatacttttt ataagctatc aagagttatt
     9541 agagcaaata aagttctctt ataacaatgc tgaactgaga aaagaaattg aaggatcgct
     9601 tatagccgat attaaaacaa ctgatttggt ggtttttgac gatattggag ctgaattagg
     9661 tagtggggta tcaaatagta ggcagtttac aaacaacacg ttaaacacgc tcttagaagc
     9721 cagacagaac aaggcaacga tcatcacaac aaacttatct ggtcctgaac taagagaagc
     9781 ctacggcgaa agaattgttt ctaggatatt taagaattca gaaggttatg cgctgaaatt
     9841 ccaacaaaca gcagacaagc gcataaaacc agtgaaaggt agtatcgcat gaataaatac
     9901 cgtaataaaa aaactgttca tcgaggtatc aagttcgatt ctatcgcaga agcagagtac
     9961 tacgatctag ccttatggca agctgaagcg aacggctgga aagtaaaact tcaggaacga
    10021 tttgagctga tgccgaaatt tgaactagac ggaaagaagt atcgcaagat cgagtatatt
    10081 cccgacttta cattttataa aaacggcaag cttgtcaaag tcatagatgt taaagggatg
    10141 cagacaaaag actttaagat caaggcaaaa ttgttttgtc ataaatatca agtgccattg
    10201 attttagcta aaaaatatcg gaatacgttc aaggaagaac ggttttaacg aggtggtcca
    10261 tcatgacaac agaagaagtg attcaaatgc gtattcgaag ccttcaacgg gagattgacg
    10321 atctggaacg aacaaaggca gtgatggtca atgaaacggc gagaaaggca atcgatttac
    10381 acatagtgaa tttaagaagg gaaattcgta gattggagga atgagcgtgg ataagaaagc
    10441 agcaatgaaa cgaatcattg aactgacaca ttctgagaat tggcaagaag acaaagaaat
    10501 agttgcagaa gtccaaaaaa tcggtaaatc aatgtggact gaaaagccta aacggaaaac
    10561 gccgagaaaa attgcaatct ggcatggtga tcgaattcta gtaacaggta ctgctgaaca
    10621 gttatctgaa attactggtc tgagcaaaaa catcatctgg gatagagcta ggagcttatg
    10681 gattgattca aaaggacgac aatttaggta tgtggaggag aaataatgga tctcattaca
    10741 caatacagtg atatcatcct caagaaaatc atgatgaaga ttcagaaaga taaaaaatca
    10801 aaagaacgag cggaattagt caagttggaa atggctgaaa caggagcagg agtgcgaagt
    10861 agcaggcatt ggaaagcagc agcaaacatt gaattctatt acaacgaaat tcaaaaaggg
    10921 ttcgatcaga tgcgtgagct ggatcggcaa acaaattgga gcaagaaact ataccaagat
    10981 cgtttcaagt ttgtagaaaa gtatagagag atactagacg aatacatgga ggaagcggaa
    11041 tgaacaccag acaccgcaga gtagcaaaac taagaaaaca ggaactgaat gtactaaaga
    11101 caaagtttga aaaagaatat ggaatttcag cagaagaaac atataaagtg gcaagtcagt
    11161 ttgttgctga tgcgagtgag actattcgta agtttgggat ttcgatatta aatgatgatc
    11221 gtaaatggga ggcagaaaga tgaaactaaa agacggattt tacactgatg cttatggaat
    11281 tggtggtttg atgatggatc taccaactaa gaatcctata aagcaagagg aatcagaaat
    11341 taaagtcggt gacatggttc gctgcgaagc agaagggttc atctatccat ttcgtggata
    11401 tgtagagcat ctctataatc actcagcgat cattcgcatt gaaaacacga tggaatgtga
    11461 caagcggtta gcgaaaagca aagagaattt agcagtggtg agattggtgg atatggaagt
    11521 tataaaatct taattttgct tttttacaac tatcctacaa caatgagcgt tattccacaa
    11581 ctggaaggag aagaggcaat tgtgaacatt ttagagaata tagatattaa gcaaacaagg
    11641 aaaaatgcta gacgattact aaaaagatac agaaatttag aacgtttggt cggaccagtg
    11701 aaaatagact tttccgtgat gactgttacc aaaaatttga aattcacaat tgacagtcaa
    11761 aacgaagaaa tcattgaagc gataagtact cgagattcgg ttatcgaagc attaacacgg
    11821 ctaagtagaa tccatttcca ggtactttat tatagttatt gttttcctaa taagatgtca
    11881 atgtatcaaa taggagaaaa attaggatat tccgatagaa ctatcgagag aatgaaggca
    11941 gtagctttgg ttgaatttgc tgaggcgtat aaatcaggag aactcatttc acgtacaaaa
    12001 taaaaaaagt cggattcctc cgactatgaa taatatttcc gacataagta ttatatcata
    12061 attgggggaa tcagaggatg gtacttttcg atgtaaagaa atatgagaca ccaagcgcga
    12121 aagatgttga tatggaacgc acaaaacata atgtcgctgt gtttctttca gcatatctat
    12181 cagctagatg tagagtaggg caacctcgag aaccaaaagt gacagcatct tattccttgg
    12241 ttccaccttc tacagctgat catatatttg aagcagaaag aatgctgatc gataaagaag
    12301 aagcacagga agaatttgag tatctgcata aattgtttgt tcgaggctat tcagcgatac
    12361 agcatccgca taagcctgat gtgactgaaa ggcgcaagaa gatattctat gatcgttata
    12421 tcaatggtct gcccatttat gtaactgctc aaaggaataa tactagcgaa gaatcggtta
    12481 aagtagaatc aaacagaatt atcatccaat ttgcttcatc gttagaactg gttgctttca
    12541 agtagccagt ttttacactt tttataccct tttattacca atttggtttc cattttatac
    12601 cttttttata ccaatcactt acctattcaa cgttgtatta tgatagtgtc gaaagattag
    12661 tgataggtct tagacaaaat aaaatgtaag ggaggaaatc tccctcatcg ttttaaatta
    12721 agcctcgata gacagcagcg gaaatattaa gaataaggat gtgaactcaa ctccttctga
    12781 attcttcgta tgctgctgtc tattaaatta tgtgttggag ggtaagaata tgaaattatc
    12841 gattgaaggt acttcaggag aaataaaaga aatcctctca gctatttgta atagccgaga
    12901 gattagcaat ttaatcaata tagataattt aaatgaatct attgttactc caagttcccg
    12961 agagaaattg cagaaatctg atcagcaaaa acaactaaaa atgggatatt agtagttctc
    13021 tcgcctatga tggtaacatc tttcagaaag atagatttga ctaccaaact ttgctcatca
    13081 tctttttcta tatcatcaat tttttttgag cgaaattctg caaaagaatc catcatagca
    13141 tcaataagag gatttacttt tacttcagca tcaaagtcta taggagttcc gcaaattgtt
    13201 gctcctccag tttgaataat aatattattg ttagaatttt tagcgaagag ttcaatatat
    13261 tcaatcatgt ctgaacggta atcatcaatt tttgccattt ttttaccacc ttaaattatt
    13321 tcagcggacc actcgctgat aaataaaatt atacacttag tatttatttt cacaatatta
    13381 atttatcgta ataacttttg agtaaataga acaaaaaacc tgcactagtt tccgctagta
    13441 caggcagtga ctatatcggt tgataatcta gcatatatta aaaataattg caagaaaaga
    13501 aatttatagt ggtttatacc aaattatcaa agcaatgtta ttttgttgct gtctattgtt
    13561 ttttaattat tcacacgata actaaaggtg ggtgaagaga aatgattcca ttaataattt
    13621 caatttttgc gctctgtctt aatgtctata tgattggatt taaaaatggg caaaataaaa
    13681 aatagtagca gccaagaata attttatagt gtcactgtgg cggaaagggt agacgctaag
    13741 catgtgtgct aggtcaatgc ttcggcaacc atgcaaggtt cgattccttg ccagtgactt
    13801 tagtggatat ccaaggtaaa aggaacggaa gtgggaatca ggcatgattc ggtaggataa
    13861 ctgcgagggc atattaagtt gaccacttaa gtaaaataat tagggagatg cacctagaaa
    13921 tagagtcggt cgctctatag ggtagtcatc aaattagact ttgctatggt tagaccctaa
    13981 gccagtaaag ttgtggcggt gaacccttgc cgctttgacg tgaagtatct gtggtgatac
    14041 gtctgacttt taatcagaag gtgcaggttc gactcctgtc acgtcaatta gcaaccgagg
    14101 gtggtatgaa ctcgtgtggt gcgagcccta gggaggaaca ggataaccgc ctgtgtgtag
    14161 gttgctagta catattagat cactcgttga gtggtctttt tattttgcaa aaaggaggta
    14221 acaacaatgt atagaccaca atacttagaa cagaagcatg aagtaatcac tgtgcaaaac
    14281 ggtaacggtg agatagtacg aaagtataga agaccaataa agagcaatac atataaacga
    14341 aaggaaagca atgaagttat tccattgtat ggcaaaagaa tagctaagta ttaaataaga
    14401 ttgcgaaagg agatgggaca tgaccgagga attctataga tggttattac agttgataag
    14461 agaagattgt ttggttaagt tctatcagtc tcctaaatgg cgcaggctta gagagaaagc
    14521 gatgaaacga gatcactatg aatgccaaga gtgtagaaga ctaggtaagt atcatagagt
    14581 agagaacgtt catcatataa aggaagtcaa ggatagacct gacttagctt tagatttaga
    14641 taatcttatt tgtttatgtg ttgaacatca taatgaagtt catggcagat atcttacagc
    14701 attagataaa caagagaaga agatagaaag ctttgctaac ttcgatgcaa gtgaaaggtg
    14761 gtaagtgcat gatcatcaat gacaatggca gagagtatga cacagaaaag attgaagagt
    14821 attcatctta tactcaagga ttaattaaac gtttgatata cgttcgctat gtaggtatta
    14881 gggatctgtt atcagataac tgttgcagta aatacaaagt gaatcaagta agagaagcgt
    14941 tgaataaaga taataacgtt gaaagaataa aaaatatttt tggatatagc attgaagaga
    15001 ttaattatta cattgacttc gctgaagctt tcattccgat ggtgagataa ccccccctta
    15061 aaataaatcg caaatttttt gggggtgatg aaacggaggg ggctgtcagg aaaagagatt
    15121 ttttcgaact ttatcatgaa aggagggcta aaatgtttaa aaacgaattg tctcaaaatc
    15181 gctacagaga aaaattacgc cgctctttaa taagccaatt ggaaagtcag aaaacaaata
    15241 ttgagccatt cttagataat gttgatcgtt atatcagttt atgggaaacg gcgatatcac
    15301 tggaagaaga tatatccgag aacggcatta gactggagaa tggtaaaaag aatgaatcag
    15361 tagcgttgct tgtttctgtc aacaaacaaa tgggattgat gttggataaa cttgccatta
    15421 ctcctgaatt ggtaggtgaa gcaaatgaat caattcctga gttataagca tattgaaaat
    15481 tggttcaaag ctatagaaga aggcactatc aaggtatgca aagagcaatt attgctaaaa
    15541 aattatctag aagaaagagt ctttactaga gaagatattt acttcgataa gcagatggta
    15601 gaggattcaa tcaatatacc agcacaatac tttccattcg aattaattcc gtgggaaaaa
    15661 tttctacaat gttttattta tggtgttcga tggaaaaaag ataaaacact agtgttcaat
    15721 agatatcttt cattaatggg acgtggtaat ggtaaaactg gttttgcttc ttggaacaac
    15781 ttctttctac taaccgctaa acacggtatt aaaaattatg atattgatat ctatgccaat
    15841 aatgaaagcc aagcaaagac tagttttgat gatgtattta aagtaattaa agatcatcct
    15901 gatttagata aaaaagtatt taaagctacg aaggaagtta ttcaaaatat cgctacaaac
    15961 agcaaacttc gttataacac ggcaaatgct agaacaaaag atgggaagcg accaggtgca
    16021 aaccgctttg atgaaattca cgaaaatgaa gattattcaa tgataaatgt ggctacttct
    16081 ggtggtggta aaattcgaga ttatagagaa ttttatgata caactaatgg tcatgttcgt
    16141 ggtggtccgc ttgatgacat tatagaagaa tcaaaaatga ttctttctgg agaacttgga
    16201 attgacaagg atggagcaga attttctagt ttgtttccat ttatttgtcg cttggataac
    16261 gataatgaag ttgatgatcc cgacatgtgg gaaaaagctt gtccaactat taattacaat
    16321 gcagatttaa aacggaaaat gtttcaagaa tactctcaaa tgcaacgtaa tgctggttta
    16381 agacttacgt tcatgaccaa acgaatgaac agacctatgg aagatacacg atttgctgtt
    16441 gcttcatatg atgatgttct gcatacgaaa gaaaaagaat ttcctgaaaa aatggatgaa
    16501 gtgataggaa cagtcgattt tgctgataga cgagattttg ccagcgttgg gttgctagga
    16561 aaatacgata aagatgttta ttttacacaa catactttta tccacgaatc agcccttcga
    16621 ttacaaaaca tcaaacgaga ggttatagat atttctatag atcaaggaaa atcacagatc
    16681 gttcatggaa aaaatataga agctgattat attgtaggtt ggtttcttga aatgagtaat
    16741 aaatattata ttaaaaaaat cgctatggat atgtaccgtg caaaaatatt gaagcccgct
    16801 ttagaagaag caggttttac tgtggaaatt gttcgaagcg gatctgttac acatggtatg
    16861 ttaaaagatc tggttgatga cctttttatt aatcaacgtt tattttttgg tgacgatgcg
    16921 attatgcgtt ggtattgcat gaatgtatat gaagagcata tttctaatgg aaatatacgc
    16981 tatgaaaaaa tagaacctga aactagaaaa acggatggct ttttttcatt ccttcatggt
    17041 ttgaattttt tagatgatat ttatgattct gctcctgtaa cagtcacaaa tagctcagta
    17101 gaaaatacag gaactggatt tactcctcta gtattctaac ttgaaaggag gtgagaaagt
    17161 ggggattttt caaaaggcgg taggatactt cacaaaaaaa gcaacggttc ctttagaaga
    17221 atacttttgt aaattgcaag ttgattttgt gtatcgaaaa tttgcgattg aaacttgtat
    17281 tgatttgatt gcaaatgcga tgagtaaagc ggaattcaag tcatatgaag atggaaaaaa
    17341 taaaaagaat gatctttact ataggctgaa tgtagctcct aataagaaaa ataatgcaac
    17401 agaatttaga aaaaaactga tcaggagatt aatattctac aatgaagtat tgatcgtttc
    17461 tccgtctaat aattctagcg aaatatttat tgcggatagt tgggatgtca cagaatatgc
    17521 attgaaagat gatgtgtttt ctcaagtgca aattaacaac atagtccttg atagagaatt
    17581 tctagaaagt gatgttatct atataaaata cgcagatcaa caaattaggc aactagtcga
    17641 tgcgtattat caagcgtatg ggaaactcat ttctagtgcc atgaatgttt acaagcgctc
    17701 taacgctcgt agatacgtac tgaaagggaa tttattccga ccgcaagaca atacaacaca
    17761 agatcaaatc aataaaatga tgacatcaca atttaaggat tttatggaag ctgataatgc
    17821 aggtgcggta tttcaattac aaaatgagta cacattagaa gatttcagcg gaaacttcca
    17881 aagcaattca agagatataa aaaacttaat agacgacatc tttgagatga cagcagcagc
    17941 gtttcacgtt ccgaaaaacc tactaaaggg agacatgagt gggttatcgg atcaagtgga
    18001 cgctttttta atgttcgaaa tcataccgat tgctgaactt attcaggatg cgtttaacgc
    18061 tagtctctat gaagtagaag aatacttgtc agggaatttt gtacgtgtgg atacaactat
    18121 gatcaagatt actagcttca aagatttggt tgacgctatt gatgtaggca ttagaaatgg
    18181 agtatttaca atcaacgaag gaagagaacg cgttggaaat gatcgctctg ataaggcgat
    18241 ggcagatgaa atatttataa ctaaaaacaa tcaacaagta tcgaaaggag gtgaggcgaa
    18301 tgacgacaat gaaaacattt ctagcagtaa agaatgaagg cgcagtaccg caaattttta
    18361 ttcagggatt tattggttct agttggttct ttgaagggaa tactgacaag ggaatcaaaa
    18421 atattttgga tagtctaggt gatcaagaag aaattgaagt agtaattaat tcaaacggtg
    18481 gagacgtatt tcaagggatt gctattggga acttacttaa gtcaaataaa gcaaaagtta
    18541 acgttgtgat taacggctta gccgctagtg ctgcttcaat tatcgcaatg gctggcgata
    18601 ctataaaaat ctacaacaat gcacaattga tgattcaccg cgcttccaca tacggagaag
    18661 gaaatgtcga tgacttccgt acgattgctg accaactgga atcaattgat aaatcggtaa
    18721 aggcttcata taaaacacga ttcaatggca cagatgaagc attgcaagaa cttcttgaaa
    18781 aagaatcgtt tatggatgca gaaacagctt tgagttatgg attggtcgat gaaattatcg
    18841 atgcagaaaa tagctcaggt actgaagcta aaaaagaaca aagcgttgaa gaaattttga
    18901 atgacgttaa agaaaaaaga gcagaaaaaa ttgctgcatt tacagcagca ttaaataaaa
    18961 catttggaca aggagatgta aaataatgac agttaaaaat ttaaaaggtg taacagctgc
    19021 aagcgaccaa ttgatgaaag cttttaaaga tggtaacgaa gaatctttta gcgcagctat
    19081 ggtaagctta tctaaggaaa ttcaggataa aattttagaa gaagcaacag caaaaaatca
    19141 agatcaatta gtattaatga accgtggtca gcgtgtatta actacacaag aaacaaaatt
    19201 ctataacgaa gtagtgaaaa acgaaggttt tgcaggggtc gaagaattag tgccagctac
    19261 tgtatttgaa cgtgtatttg aagatttaga acaatctcat ccactattgc aaaaaattac
    19321 ttttgttaac acaactggtg taacagaatg gattgtgtca cgtggagtca atccagcatg
    19381 gtggggtaaa ctttgcgaag ctgttaaaaa agttttagat aatggctttg atgtaattaa
    19441 catgaagcag ttcaagctat caggttatat tcctgtatgt aaggcaatgc ttgatttagg
    19501 tccagtatgg ttagatcgtt atgtccgtac tgttttagta gaatcattga gaattgcatt
    19561 agaacaagca attgttgatg gtactggtaa agatatgcca gtcggaatga tgcgtgacat
    19621 gagcaaacaa actagcggag aatatgctga aaaaaaagca gaacctatta cagctttaga
    19681 tgctgtaact atgggcggtt tgatggcgcg actatcaaaa ttcaatatcg aaggtgtgaa
    19741 tgatccgatt tatcgtaatg tgaatccttc tgatgtggtc ctaattgtga atccaactga
    19801 ttactggtct aaagtattcc cagctaagac tgtactaact gctaatggag aatacgtaca
    19861 agtattgcca gtaccagttt cagatttgca gtcaacggct gtgccagaag gaaaagcagt
    19921 tattggggta gcctcagatt acttcatggg tgtaggatct acactaaaaa ttgaagcttc
    19981 agatgaatac cattttgttg aagacgaacg catttatcta gctaaacaat atgcaaacgg
    20041 tcaacctaaa cgtaacgata gtttcattgt attagatatt agcgctttgg gaactactac
    20101 tacaactaca aaaccaacaa ccacaacaac tacaacacaa gcgtaggtga tcagaatgaa
    20161 gtatattctt tgtcagctgg caatcaatcg gtttaaatgg gagcttgaag tttgtttaac
    20221 taatctgaag aaactaggaa tcaaagatat cgtattgctt ttcagcagac acgatgatca
    20281 gattcctatt ttttttgaga aggaatatgg tgttgaagtt catgtgtacg atgatctgcg
    20341 ggacgacaaa gagtatattc cttcgattaa accatattta tggtggaaat atttagaaga
    20401 agatcattcg cgtgaggacg accgatattt ctatatcgat tcggatgtca ttttcaataa
    20461 aagaattaat ttgcgcaaat tgccttctaa agatgatgtt tggtattgta gcgactgctg
    20521 tagttatcta agtcttgatt atattagaag ctgtgaaaac ggagaaaata ttctaaaaga
    20581 tatggcaaac attgtaaatg ttacagtaga atctttggaa actataaaca ctaattcagg
    20641 aggcgcacag tgggttatta accgtcctaa agcgaattat tggaaaaagg tttatctgga
    20701 ttctaatcgg ctatatcgct accttagagg gcaaaaaaca aatatacaaa tctggacagc
    20761 cgagatgtgg gcacagcttt ggaacatgat gtatttcaat attggtccta aagttcacga
    20821 ggaattagac ttttgttttg ctactgatcc aatagaaaaa gttaaagaag taaaaatctt
    20881 acacaatgct ggagtaacaa caaacgatga agatttattt ttcaaaggga gatacgtgac
    20941 ttctacgcct tttgatgaag atttatcatt tgtaaacaag aaaaaatgct cttacgcata
    21001 tgttaaagca attaaggcgg tggttagatg acgcctgaac aagtgactga agaattgcta
    21061 atagctgtga aggataatat ttacgttacc tggaacgaag aagatgagtc aattaaaaag
    21121 atgatagcta aaaatgctgt ttatcttcaa agtaaagtga gtacaacact ttctttttct
    21181 cctgaaagct tagaatacgg attgctaatc gaaagatgta gatacgactg gaatcgtgct
    21241 ttagatgagt ttgaacaaaa tttcgctagt gagttattag gtttcattca acattatgcg
    21301 ctacaagaat atattgcagg tgatgtgaat ggcgaataat cgtagactcg aagaaacatt
    21361 caacgatggt tggttaaaga ttttgacgca aactaccaaa agaaatgaac taggaaaaaa
    21421 gattggtgta gaagatacag aaatcacttc tttaaaattt agaaatcttt ccatgagaga
    21481 tagtgatata acagctatgg atgcgatggg atcgaaatta actaagaaag taaagactcc
    21541 atttcatcca atcgccaaga aatttaataa agatcaatat tttatcgtaa tcgatagtat
    21601 gcgttacaac gttatctatg ccgattacga taatttttat atctattttt atcttgaaag
    21661 tgtgggtgaa tatggtgatt gataattcta aagaaaaaga acgtttaaat aagcaaattt
    21721 ctgctatcaa aacttcctta gaagagcatt ttggcctcaa actctttcaa gactccgtag
    21781 gcgaggatga gctacctgat gattttaatt acttcattct cgaaacagga gaaatagaaa
    21841 tgatcactga gccaaaatat agcgtgggtc aaaatctata tctaactttc tattcagaaa
    21901 atagagaaga tttaacagga gactcactag atattatttc attgattcaa aatcgttcga
    21961 ttcgttttca gagaatggat cccaatcatt taaaactaga gaaccaagat cgctatatcg
    22021 atcaattggt atttacgttt agacgattat tgaagagtga ttgtcatggc taaaaatagt
    22081 tgggagctaa aaataaatgg acatgatgaa cttcttgtgc ggatggaacg ctattcaagc
    22141 gagagcgaac gactgattaa cgaagcattg aaatcaaaag gttcggctat tgcagtggat
    22201 aggattacag aaaaaattcc tgtttctgaa gcagatttaa gaagagggca ccaacacgca
    22261 aaaaatagtc gtccacttaa gactcaatac attaatttgg gtttcatcat tagacctaca
    22321 agaaaatttg agtatttaaa atatcctgat ttggggatag gtacttctaa aagaaatcag
    22381 ccggacgaat ttatgagaag aggattaggt cttgcacttg atccaattac agaacttctg
    22441 attcgtcaat tcgataaatt aaataaatag ggggaacaac aatggctaaa acaaaaactg
    22501 tagtaacaac gttcgataac ataagtatca aacgaattgc ttttaatttt aagaacgcag
    22561 gaaatgcaat cgcaacgaat tgtaacggac aattagatgg cgaaacagaa atgcaaacgg
    22621 tggttaaaaa atgtggagcg acagaagtaa aatcaaaatc taaaccaatc aatatgacgg
    22681 taacaattac tgcacatgta ccgatggaag tttatcgacg tttcaatggg ttgaaacaag
    22741 atggacgtat taaaccaggc atttactctt acggtcctga ttccgtaggc gaagatttct
    22801 cacttgctgc agagatcgtg gatgacttcg aagaaaatag aaagttagtt ggtatgttag
    22861 catgcacttc gaatacagga ttaacattct ctattgaaaa tggtgcggat gaagtagctg
    22921 cgttagaact agaagcaaaa gttatgcaag atgaatttgg taaattttat catgaagcaa
    22981 ttgttgcaga acttgaagaa gacttaacag atcaatggat gacgaatcta tctgctgatg
    23041 tgattaaaaa aacttcagtt gtgacaacta cggccactca atcacagtaa aaaaaacgga
    23101 ggtagcgaaa tgaacgaaga ttactcaaaa attgaactaa acgatggaac aattttgaat
    23161 ttagaaccta aactgaatat caagaaatta ttgatgatca atagagattt taacacagac
    23221 gagtttgcaa aaatgactgt gggaaaagga tccatggata tttctgttat tcaaggtgcg
    23281 aaggctgtgt atattgctta ccgccaagcg aacatgactg attatatttc attcgatgaa
    23341 tttatcgata aatgggattt tgatatggct actgccagct atatttatca attgatgatg
    23401 ttcaaacaag cacgcgatgc ttatcaaaaa gaatttgaaa aagcaaataa ggaaaaaaag
    23461 cttcaaaagt aaaaatgcca aagctcttag ttgaaacgtg ggtcgatgtc tattcgatgt
    23521 tgaccgacgt tttttctatg ccttcagatt tggttttaag cgatatctgt ttagatgaca
    23581 ttttgcaaat ggcttacaac aagagtgctt atgaaggatg gaaaaactat gcaataaacc
    23641 aatcccagaa aaactaaaga aaggaggtaa aaaatggcta aaaagagaac agaagcagaa
    23701 gtaactttca tagctaacga tgacggattg aaatctacgt taaaagaaat cagtgctgaa
    23761 ttaactaaaa atagagcaga attaaaacta gaacaagctc aattacaaca gactggttct
    23821 gaatcagaca agttaggaag taaattatct tctttagaaa agcagtatga attacaaagt
    23881 caaaaagttg aagtaactag tcaacgttta gccaatgcca aaaaatatta tggagaaaat
    23941 tccaccgaag ttcagaaact tgaaagagaa ctgattaatc aacaaacagc tcagcaaagg
    24001 ttatctaatg atatagataa aacgagtaag gcattggctc aagcaaaagg cgaaatacag
    24061 acgtacgagt ctacaatgca acagttggat agtgaacaaa aaaatgttca agctagtgct
    24121 tctctgattg aatccgaata caaaaaatgg caagtaactg ctggtcaatc agcttctgaa
    24181 tccgagaaat tagcgaaagc ccaagaatat gtttctcaac aatctgaaaa tgcagagaaa
    24241 acgatagata tcctgagacg acagttagaa gctacacagt ctgagtttgg cgctacatcc
    24301 acagaagcaa tgcagatgga ggcgaagctt aatgatgctg aacgtgaatt tgaagagtta
    24361 ggacaagctg ctaaaaatgt agatacaact aacttggacg atatcggaag caaaatagat
    24421 atgaataatt taatggaagc ttctgacgtt ttaagcgaca ttggcgataa gcttacagaa
    24481 ttagggaaac aagcagtgga ctctgctaac agtgtaggta gttcccagag taaaatacaa
    24541 gctaattttg gtttgactaa acaagaggct gaagaattaa cgaatgtagc cagagacatt
    24601 tattataaag gttttggaga atcgttagat cagtccacag atgcattgat tttggtaaag
    24661 cgtaatttag gcgatttaaa taatcaagat ttacaaaata ttacggaaca agctatggtc
    24721 ctagaaaaca ccatgggcgc tgatatggat gaaacgttac gtggtgtaaa tggcttaatg
    24781 gtcaacttcg gattgagcgc tcaagatgca atggatttaa tggtttcggg tactcaaaac
    24841 ggtttagata aaacgcacga attaggcgac aatatggcag aatatagcca attatggagt
    24901 caaatgggat attcagctga tgaaacgttc ggaatgcttc aaaatggttt agatgcgggt
    24961 gcttataacc ttgataaagt caatgactta gttaaggaaa tgggaatatc gttaacagat
    25021 ggtcgatttg agcaaaacat ggatatgttt agtgaaagta ctagaaaagc ttttgaagag
    25081 tggaaaaatg gcggaggaac acaaaaagac gttattaatt ccatgattca agattttagc
    25141 aatatggatg gtcaatacga ccaattaaat aaagcttcta caatttggtc tgcacttggc
    25201 gaagataacg cgatgaaagt tgtccaatct ttgactgatg ttaaccatac atttgatgat
    25261 gttagtggat ctgcacaaaa aatgaatgaa gactctacta ctccgttaca agaattaaac
    25321 ggaaaaatag ctgaattaaa ggattcatta gctcctatag gcaacacaat catagatgca
    25381 ctcgaaccag taattgattt tctaggaaag atggctgatg cgtttaataa tcttccacaa
    25441 ccagtacagg attatgccgt agcgattggc ggattgactg ctgcatttac tttattaatg
    25501 ccaataatag ttggcttcat ggctctaggt ggtcctacta cattaataat aggagcagtt
    25561 attactgcta ttgctggagt tatagcaatt ataaaaaact ggggtgcaat tactgactgg
    25621 tttagtggtt tatggaaaaa atttactgat tggttgggtg atacttggga aagtataaaa
    25681 gacggagcct catcagtttg ggatggggtt aaagaaacct ggtctggatt tgtagattgg
    25741 gttcaagata tttggcaagg cgtttctgat tggtttggag agttatggag cggattagtt
    25801 gaaggagctt ccaacatctg gcaaggagtc caagagactt ggcaaacatt cattgattgg
    25861 gtttcaaata tttggaacgg agtcaaagaa gtatggtcga ttatttgggc agacattgta
    25921 ggaattgttc aaataccatg gacattaata acgtcattga ttcaagctgg tattaatatt
    25981 atcgtgggta tttttgatgt agctggacag ttattaggcg cagcttggca agctgtttgg
    26041 acacctattt ctgatttcct taaaaatact tgggatacta tgacacaatg gataagcatc
    26101 gcttggaatg gaattgtaac tacattccat actatatttg atccagtagt ggcatggtgg
    26161 aatggtatat ggacatctat tagtactacg gcttcaaata tttggaactc aattagtgca
    26221 acagcttcta gtatttggaa tagtatcaag aatacaatca ctagcttggt acaagcagct
    26281 gctacagtaa ttcaaaatat ttggtcaact gtatctagtt ggttaggtgg aatttggaat
    26341 tcaatcagct ctacagcatc aaatatctgg agtagcgtga ctagcagtat aagcaatgct
    26401 ataaacgcag ctaaaagtgc cattcaaagt gtttggaata gtatatcttc gtggatcagc
    26461 ggaatttgga acggtatcaa aaacactgct ttgaatcttt ggaatggaat tacaagcact
    26521 attagctcta aagtaaacga tggaaaaaat gcaatttcaa gcggttggtc caatctaaca
    26581 ggtattgttt ccgacatatt caataatgtt aaaagcacga tagctaatat atgggaaggt
    26641 atcaaaaaga ctgttagcgc tccgattgat tggattagag ataaaatcag tagtgtcttt
    26701 gataatttga atatttcgat accacatatt ccgttaccac attttaaatt gagcggagaa
    26761 ttcaatccat tgaaggggaa aatcccaaca ttgggtgttg attggtatgc gaaaggtagt
    26821 gtgtttaatt ctccaaatat tatcggtgtc ggtgaagcag gacctgaagc agttttacct
    26881 ttgaaaagat ctgtgctgca agaaattggg gatcgtatct tgagtagcac ctcagtttca
    26941 tctagggcac aaacgattca acctgtgaac aattacgaat tcaatttcac aattgatggt
    27001 aacgcagatg aggttactat gaagcaaaca actcaacaaa tcattgatag cattacaaaa
    27061 gttcaaaatg ataatgcttc ggcatggcgt taaacaggag agtatttctc ctgttttttt
    27121 agttttaaaa aggatgtgaa aaaatgactg attgtataca ttctataatc gatggatttc
    27181 ctgattattt gcataaattg gctttagcgg aaagaccaac cataccttct ccaaaaagac
    27241 agagagttga aacttctgtt ttaggacggc taggtggctt agtacaagat tactcgtttg
    27301 aagacatgtc gtttacattg cactataact atttagaaga tgtggaagac catcaagcat
    27361 tcaagcaatc gttttatatc atgcgtcatt ggttaaacta tgcaaagaaa ttagaattct
    27421 ctgatgatcc caacgtctat tatgttatcc agactatcga tattggggat gcagaaaacg
    27481 atattgttga atggggagag ttcgatgtaa atatcactgc gaaaccattc gcaagagttc
    27541 aagaagatgt acctataacc gtagataaac cacagtcatt taacttgctg aataatagtt
    27601 tagaagaaag ttttccaaag attatcatca ctccttcagc tacttcatgc caattcacct
    27661 taaatgatta tgtgtttagt tttgaaggct tagtagtggg aactgacata gtcattgata
    27721 gtgatttgat gctttgctac gaagagcaat cggacggaga tattttagat cggtccaaca
    27781 aaatgaagac catgcaatat ccaacgttgc aagtggatat taatcatttt aattgtactg
    27841 gtttgagcaa aatacaaatt tatcgtaatg ggttaaggta ggtgaaatag atgatcgata
    27901 atttactaac tatttacgat aaaaatgacg cgaataattt agctgaacat ttatatgata
    27961 cgcaaggttt aggcgctttg tcagactggt taacagctac tgttagcaat aaactaaacg
    28021 gagccgagat atttcagggt acttattcaa taaacggaac taatgcagat ttgattgtag
    28081 aaggacgtat tattcagtgt tatgtagatg aaaatcgagc aaaacagcgt ctacggattt
    28141 attatgcaaa aacttctgta ataggcaata cgatagaagt aaaagctgaa cctattttca
    28201 atgatataag aaaatcggtg ttgaataaat atgacagcgg aacagaaaaa atcactgcta
    28261 ctcaggcatg gcaaaacgca aaagttttag cgaaaccagc tatcccttcg cagttttctt
    28321 tctcgtcatt agtagatacg cttgctaatg tgaagataga aaaggcgaat tttttagaat
    28381 tctttggtgg aaaagaggga tctattctag atcgatttca tggtgagttt ctaaaagata
    28441 ataacacatt acgtcatgaa aaaagtctag gtacggatca taaaatcaaa gcgatttata
    28501 ctaaaaactt aactggtctt gacttagaga tagatgctca aagcgtttta gttggagttt
    28561 atccattcat tagcagttct tcagaaggag aagacgagat cactctacca gaagaagtta
    28621 ttttcacgga ttacgtggat gattatcctg ctggatatgt ttcttttgtt gattttaaag
    28681 acaaagcgac tgatgtagcc acattaaggg aagttgctaa agactggttg aaaacaaaca
    28741 tagataaaca aaaaccacaa gtgagtggtt cgattgaatt agtaccattg aggcatcaaa
    28801 gaggctatga aaaatttgtt gatctagaaa aagtttcgat gggtgacgga gtagatgtgt
    28861 atcatccaca gttaaaagtg aatatgtcag cgagaatcgt ggaatatacg tttaatgttt
    28921 taactaattc atacgataaa ttagttgtag gaaacgtcaa aacaaacttc ttagaaaata
    28981 cagagaataa tgtcagcaat ttgattaatg atgccattga tcaattgaaa aatgttggcg
    29041 aaatcagtga tttaatcaat gatattgtag atcatcaaac tgatatgatt actggtcaaa
    29101 atggtggtta tgttttatta gatcctaaag aagcgcctag tcgtattttg attatggaca
    29161 caccagataa gaataccgca aggaatgttt tacaaatcaa caatgctggt attggttttt
    29221 ctaaaactgg cattaatgga acatatgaaa cggcatggac gttagatggc ggattcaatg
    29281 cctcgtttat tacggctggt gaaatagtag gaattactat tagaggtact acattaatta
    29341 gtgatggtgc tgattataga acaagtattg ctaatggcaa aatgacttgg tactcaaaaa
    29401 aagttaacaa agatattatg gagctagaag cacgtgatta tgtaagtgct gatgccggta
    29461 ttgtatcata caccatgaaa actggtggtg gtttcatgat tagaaatcca cagggtaact
    29521 tggtttttag tacgtgggat aatggtaata acagaccgtt tctatctttt ggtgcgccca
    29581 atttcaggta tagcaatgct agttatgtaa cttctggcga cggtagttct ttaagcatta
    29641 atggtagtgc gggtaactca tgggaattta aggtagctgg taggactatg aaatttacta
    29701 gtgatggtat gctaacgtta ccaggttgtt tttttggttc atgggaagat gggaaacttg
    29761 ctaggtttga acaatcaacg gtacaagtat ataaagattt tactgttaga ggtactaaaa
    29821 actcaactgt accaacagaa cattatggac aacgactatt gaacgcttat gaaactccag
    29881 aatattattt cgctgattat ggggaagccg ttacaggtga cgatggtaaa gttcgtgttg
    29941 atattgaccc catgtttgct gagacagtaa atctaagtcg gtatatgaca catgtgacac
    30001 ctacagaact agttttgtgt gctgttactc atgaagatat tgaccatttc atcattgaaa
    30061 ctagtaagcc aaacgtatta gttagatgga atttagtggc acaccgtcta gggtatgaag
    30121 atattagatt aaaagaggat acagcatatg atagcacagt gcttgaccaa aaacgttttt
    30181 aaaacgaaga caaggaggta tataaatggc tagcagttta tataatttgg ctttagattt
    30241 cagcaaagaa ttaaactaca ccaaagctat tatggctcgt cagggtgata aagggattac
    30301 ggtgacggtt aaaccatatt taaatggctt gcagatggat acgagtggcg gaacatttac
    30361 tttaaaagga acaacaccat ctaaccgtta cgtagataat gttgcaacta gcgtaactag
    30421 tgaagaagtc acgttttctc ttgatggcac atttatgagt gaagcaggat attataaaca
    30481 ctgctacgta gaatatagaa aagacaatca aattctaaca acgcaagata tcattttttt
    30541 ctcactagga gtgtctgaca tttcgcaagg tcaagccgat gaatatgttt cgcaattaga
    30601 agagttgatt cgaaagtata atgaaacttt tgatgctttt atggctgaaa ctaaaggtag
    30661 agtggatagc ttaaatcaac agattactga tttaactggt caagctaaaa cgctacaaga
    30721 caagttagat gctctgaaag aagaaatttc taagttaggt aacttacaag tgatgtacag
    30781 taacagcatt gatttcgggg gctatgatta ttcggggaat ccgaatttga tggctaatat
    30841 aaacgctgat agcttctcgc aaggtagtgg tgccttatct gttgtagatg atggtgacga
    30901 ggtagtgatt acgcttgatc caaaccataa attagaggta ttaaaaccga aaagtcaacc
    30961 agccctatta acaggcaaaa catataccgt gagtgtagaa attatgttag aaggtgattt
    31021 cactggagac cctagcaaga taggcctaag atatattaaa atgcctaact gggtatcaga
    31081 gctatatacg cgtaatacat taactgctac taagggtgta tggcaaaaac taactggcac
    31141 cgttaaaatt actgctgcga gtgataacgc tgaaagctgg cttataatgc tacaaaataa
    31201 agacgctaat aacagcctat ccggcaaact acgtttgaga cacgctaaac ttgaagaagg
    31261 ctctacagct acaccatatc agcctaactt attggcagaa ccttataata tgtgtcgcga
    31321 atatcctaac gaaaatattg ccgatcctaa agttaagttc ccaatcaaat ctggcgacca
    31381 ccaaatatat caaggttaca tggaagaaga tcttatgata ggtcaaacgt atactatcac
    31441 acttaaagga acaaaacccg caagtcaaac ctttgtagcg tataatcatt ggactgttcg
    31501 tttaggagaa ctaaagccag ttgatgggtt gacagacgta tggtctctaa cattcacacc
    31561 aacgaatgtt gcggcgatgc ctaaactttt tcgtgtttat caatatccac aatcaacagt
    31621 aggcgcatgc caaattgact ggctcaagat tgaaaaaggc aacacacgaa ccccgaatat
    31681 tagtgagtat aaatatcgtg gtactggtat gcgtgattca aataacccaa aagactatgt
    31741 ttgggatcta gcaccagaat atgtcgaaga taatttggcc acagatatta aaatttctga
    31801 aattactggt aaagcaaaca attataccga tgggaaagta tcggagatta attcgcagtt
    31861 gactgcttca attaatgaag tagacaccac agctaaggat gctcaaacaa aagcgaatgc
    31921 taatgcgact gctatagatg aacgcattaa tgatacagct actaccgcat tttatggcgc
    31981 acaaggtgaa gtctctaaca aaacgaaagt agcggagtat ggagtaggaa cagggtatac
    32041 tactacagct gtaggagaaa cacatttcga acgtcaatct aacggatacg ttaaatgctt
    32101 aaaagctggt aagtattcaa ttagtgcgca aatacgtgtg caattgggcg ggaaatatgc
    32161 ttcatggtta tatactgatt tatataaaga tggaacttct gttgataatt tagtatctta
    32221 tggggtcgac gccttgcaaa atagatttgc agctagcgga aacattgtaa ctgatttaga
    32281 agtaaacgat gtactaaata tgcgtactga aatcggcgtt gcagatggaa ttttacaatt
    32341 tacatcttgc cgtactttag tcttgactag actatctgat taatacaata tttataattt
    32401 tgctatcaac acgctcaaag gagggtgttt tttattttgc aatgaaagga ggctagttgg
    32461 ttgaaagacg aagcaataca agacgtggta gaacgcttag tgcgtattga aacgaaactg
    32521 gataattacg aattattacg cgaaaaagcg gaaagtgcaa aagatagagc ggatcaggca
    32581 tattctattg cgcttaataa tgcggaagat atcaaagaaa tgaaagccaa taataaatgg
    32641 tcgtggggtt acatgatcgg tttaggcgtt acgatcattg gctatttctt gactaaattg
    32701 taaaggaggt gagaagaaat gattttaccc gataagtatt atcaagtcat taaatgggca
    32761 gttttaacag tattaccagc tgcttctgtg ttagtagcca cgttagggaa agcgtatgga
    32821 tggaatggaa cagatatgac agtactcact atcaatgcag tagcaacatt tttaggtgtt
    32881 atcactggtg tgtcggctta taatttgaaa aaataggagg aaacaaatga aaaagaaaat
    32941 tactattact gcgatgagcc tattaacggc tcttttttta ttgccaatta atgggtttgc
    33001 ctatactatc aacaatgaat ttaatttggg cgcaaatgaa ggtagctcac aagtagcaaa
    33061 taatcagtac attttactgc atgaaacggc taatgaaaca gcaacaggac gcaatgaagc
    33121 gcagtatatg caacgttcat ggactagtgc ttacactgct tacattgtgg gtgatggcgg
    33181 aattgtttac caagttggac aacctggtta tgtacagtac ggtgctggtt cgtatgctaa
    33241 tgccaacagt cctgtgcaga ttgagttaca acacacacat aataaagcaa cttttgaaaa
    33301 gaactataaa gcatacgttg aattggcgag agattccgct aagaaatacg gtattccgct
    33361 tacattggac acgccttata accaaccagg aatcaaatca catttatggg taacacaaaa
    33421 catctggggc gatcatacag atccttatgg ttatctttct gaaatgggcg taagtaaaga
    33481 aaaattagca tatgatttag ctcatggatt taccgatgaa aatccaacaa cttctgaaaa
    33541 caagcctgtc attgatccaa cacgagctgg tgcagctaat cctacactga cagatggaac
    33601 aaactacgct catattgatc agtttgggga aattgaaaat gcaaacttgc atgtagctgg
    33661 atggcatatt gctaactata aatacgagta tattttcatt atggattaca atactgggaa
    33721 agaattagct agagtaaaag ctgatggaat ttatagaccg gatgtaaatc aagcgtatgg
    33781 gacatctgga aatgttggct atcatgtatc ttttaacatg cgtaacttcc ctaataagaa
    33841 agtctatgtc atgatgcgtg caacgaatga tccagaagga aacactaaag gcggtgcgca
    33901 agatttccat gacaaacgtt ggtatttaaa tattccacaa cgataaaaaa tccccccctc
    33961 tttgaactga accccaaaag ttgaactatt taatggactg tttccgatat tctactggag
    34021 atagtccatt taactttagt tttatccttt tgttattata ccacctaata tactcattta
    34081 atttactttg aaatatctca attgatcgga atttttctcg ataaaaaaac tctgatttaa
    34141 gcacaccaaa aaaattttct attacagaat tatctaagca atttcctttt ctagacatgc
    34201 tttgaataat gttattctct tttaattttt tttgatattg tggcatctga tactgccatc
    34261 cttgatctga atgtagaatc agtgaaccct cagttccctt ttttttaatt gcttgttgaa
    34321 gcatttcttc aatcagttta tatgttggac tagttgatat actataacta attatttctc
    34381 cgttaaataa atcaagtata ggagatagat agatttttct tccttttatc ttgaattcag
    34441 tgacgtctgt cacccatttt ttattgggtg tatctactga aaaatttcgt tttaacacat
    34501 tcttggcaat ttttcctact gttcctttat aagatttata tcgctttatt cggatttgac
    34561 aggtaagtcc catttgggac attaattttc taactgtttt atgattgatt gtatatcctt
    34621 tcatctttaa cgctaaagtg actctacgat aaccataaga gtttcttgat tcttttacaa
    34681 tcgctgtaat ttcttgcttt atcttgctat atttatctgg cttatctaat ttttttaccc
    34741 agtaataata agttgacttc gctaattgtg caattgaaag taatagattc aatttaaatt
    34801 cttttttgag ctgaaggatt gttttaacct tgatttcttc ttgctcaaat cttgttcttg
    34861 aatcaaggtt tctaactttt ttaaatatgc gttctctgct cttaaacgaa taacttcttc
    34921 ttcaagagac tcatctttaa gttttttagg aatgtttagc ttggaattca tactaatttt
    34981 tctgcccctt ttttggctct caagtgaaga agcaccgcct tcttcatatt gctctatcca
    35041 tttacttaga gttctatttg aaccgatatt aaatttttta gcagtttctt ggatagaaag
    35101 accatttgtt tccatatatt ctataacatc aagtttaaat tttgtagtgt agcttttgcc
    35161 acctccaacc aagccttccc aaccatgata gttataaatc cttacccaat gtctaaccag
    35221 tgtacgattt atttgatatt tatgtgcaag atatttgtag ccgccttcgt tatttaaata
    35281 gtctgaaact acttttttct taaaaacaaa tgtatatttc cgcaaaaaaa gcacc
//
LOCUS       DAIGUC010000029        33919 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.029, whole genome shotgun sequence.
ACCESSION   DAIGUC010000029 DAIGUC010000000
VERSION     DAIGUC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.029"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            156..2054
                     /locus_tag="NOB46_001503"
     CDS             156..2054
                     /locus_tag="NOB46_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HCI1058441.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(2353..3072)
                     /locus_tag="NOB46_001504"
     CDS             complement(2353..3072)
                     /locus_tag="NOB46_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HCI1058442.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            3409..3741
                     /locus_tag="NOB46_001505"
     CDS             3409..3741
                     /locus_tag="NOB46_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058443.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            3728..5731
                     /locus_tag="NOB46_001506"
     CDS             3728..5731
                     /locus_tag="NOB46_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCI1058444.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            5750..6220
                     /locus_tag="NOB46_001507"
     CDS             5750..6220
                     /locus_tag="NOB46_001507"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCI1058445.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            6241..6825
                     /locus_tag="NOB46_001508"
     CDS             6241..6825
                     /locus_tag="NOB46_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HCI1058446.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            6840..7826
                     /locus_tag="NOB46_001509"
     CDS             6840..7826
                     /locus_tag="NOB46_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HCI1058447.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            7816..8127
                     /locus_tag="NOB46_001510"
     CDS             7816..8127
                     /locus_tag="NOB46_001510"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCI1058448.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            8149..9930
                     /locus_tag="NOB46_001511"
     CDS             8149..9930
                     /locus_tag="NOB46_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCI1058449.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            9923..11299
                     /locus_tag="NOB46_001512"
     CDS             9923..11299
                     /locus_tag="NOB46_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCI1058450.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            11306..11941
                     /locus_tag="NOB46_001513"
     CDS             11306..11941
                     /locus_tag="NOB46_001513"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCI1058451.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            11971..13326
                     /locus_tag="NOB46_001514"
     CDS             11971..13326
                     /locus_tag="NOB46_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCI1058452.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(13518..14912)
                     /locus_tag="NOB46_001515"
     CDS             complement(13518..14912)
                     /locus_tag="NOB46_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI1058453.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            15004..15975
                     /locus_tag="NOB46_001516"
     CDS             15004..15975
                     /locus_tag="NOB46_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCI1058454.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            15972..16754
                     /locus_tag="NOB46_001517"
     CDS             15972..16754
                     /locus_tag="NOB46_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCI1058455.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(16923..17294)
                     /locus_tag="NOB46_001518"
     CDS             complement(16923..17294)
                     /locus_tag="NOB46_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1058456.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            17428..17871
                     /locus_tag="NOB46_001519"
     CDS             17428..17871
                     /locus_tag="NOB46_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCI1058457.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(17914..18723)
                     /gene="yidA"
                     /locus_tag="NOB46_001520"
     CDS             complement(17914..18723)
                     /gene="yidA"
                     /locus_tag="NOB46_001520"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCI1058458.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(18742..20109)
                     /locus_tag="NOB46_001521"
     CDS             complement(18742..20109)
                     /locus_tag="NOB46_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1058459.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(20093..20923)
                     /locus_tag="NOB46_001522"
     CDS             complement(20093..20923)
                     /locus_tag="NOB46_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCI1058460.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            21086..21523
                     /locus_tag="NOB46_001523"
     CDS             21086..21523
                     /locus_tag="NOB46_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCI1058461.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            21599..22219
                     /locus_tag="NOB46_001524"
     CDS             21599..22219
                     /locus_tag="NOB46_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HCI1058462.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            22408..22914
                     /locus_tag="NOB46_001525"
     CDS             22408..22914
                     /locus_tag="NOB46_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HCI1058463.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            22931..23830
                     /locus_tag="NOB46_001526"
     CDS             22931..23830
                     /locus_tag="NOB46_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCI1058464.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            23917..24801
                     /locus_tag="NOB46_001527"
     CDS             23917..24801
                     /locus_tag="NOB46_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI1058465.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(24993..25064)
                     /locus_tag="NOB46_001528"
     tRNA            complement(24993..25064)
                     /locus_tag="NOB46_001528"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25029..25031),aa:Arg,seq:ccg)
     gene            25124..26458
                     /gene="rpoN"
                     /locus_tag="NOB46_001529"
     CDS             25124..26458
                     /gene="rpoN"
                     /locus_tag="NOB46_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCI1058466.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            26607..27698
                     /locus_tag="NOB46_001530"
     CDS             26607..27698
                     /locus_tag="NOB46_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HCI1058467.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            27739..28740
                     /gene="gap"
                     /locus_tag="NOB46_001531"
     CDS             27739..28740
                     /gene="gap"
                     /locus_tag="NOB46_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI1058468.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            28850..30040
                     /locus_tag="NOB46_001532"
     CDS             28850..30040
                     /locus_tag="NOB46_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCI1058469.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            30144..30899
                     /locus_tag="NOB46_001533"
     CDS             30144..30899
                     /locus_tag="NOB46_001533"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI1058470.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            31015..32313
                     /gene="eno"
                     /locus_tag="NOB46_001534"
     CDS             31015..32313
                     /gene="eno"
                     /locus_tag="NOB46_001534"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCI1058471.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            32712..33851
                     /locus_tag="NOB46_001535"
     CDS             32712..33851
                     /locus_tag="NOB46_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HCI1058472.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        11209 a         6006 c         7217 g         9487 t
ORIGIN      
        1 aaaaatatag aaggaagctg gacatttatt gttcccagct tcttttttgt atagacctat
       61 ttctattttt ttattatatt ggatatatat attcattgaa aatagagcat aacaacttta
      121 taatgttgag tataccaatt tttggaggcg ttttaatgga ccgctattta gatttacttt
      181 cagagaagtt ccctacaacg gaagatgtca tcacggaaat catcaatctc gaagcaattt
      241 tgcagcttcc aaaaggaaca gagttatttt tgagcgatat acatggcgaa tttcctgctt
      301 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gaccttttct
      361 ctgaacaaat gacggaaacg gagatcagcc aattcactat ttttacggct tatccagaat
      421 atgtgttgac gactgattgg tacaaaaaac aagataaatc ccagctgatc catcgtttga
      481 tcgatctttt acggtttacg acagtcaaat acactcgatc aaaagttcga aaaggattgc
      541 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgatcgt atcaacggga
      601 aaaaagacta tgtaaaaaaa atcattgaac aacttgtctt gatgaaggaa gaagaaaaat
      661 ttttaacaaa acttgcgcag acgatccaaa aatctgtcat cgatcatttg catatcgtgg
      721 gtgatatttt tgatcgagga actcaagcag ccaaagtaat ggatcgaatc atggattttt
      781 cctctgtaga tatccagtgg gggaatcatg atattttgtg gattggtgcg tattgcggct
      841 ctgaggcatg tttattgacg cttttacgga ttgccgcacg ctacaactat ttatttgaat
      901 tagagaaaga atatggatta aatttacgtc cattattttc ttttgcccat caaacctatc
      961 agaagaatcc agtatttacc cctaaaaaca ggaaagatct atctgaaaga gagcaagaag
     1021 aattagaaaa gatccatcaa gcactttcta tcctccaatt caaatcagaa catcagttgt
     1081 tgaatcgacg acctgaattt aaaatggacg atcgtaaatt gttggaaaaa atcaactatg
     1141 aggaatcaac gatcgtttta gaaggtcagc tctatgagtt gaaagggact tgttttcaaa
     1201 cgatccagcc agatgatcct aaaaaattct tggaagagga acaaaaagtg atcgatagtt
     1261 tgatgtattc attccagcac tcgttaagaa tgcaaaaaca catgacgttt ttgatcgaaa
     1321 aagggggaat gtatctcacg aacaatcagc atgtactgtt ccatggctgt atacctgtag
     1381 atgaaaaggg gcagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
     1441 tgggattttt tgaaaaacag ataactgaaa gcgcaaaaga tttgactgca aatgaagatt
     1501 tggcgaccga tttgatttgg tatgcgtgga gcgggccatt ttcgccttta ttcggcaaga
     1561 gtaaaatggc aacttttgag cgctattttc tcacagagcc tcatacgcac gtcgaaaaaa
     1621 gcaatcccta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttggcagaat
     1681 tcgatgcaaa agaagaaggt tcagcaatca tcaatggaca cacgccagta aaagtaaaaa
     1741 aaggagagtc accgatcaaa gcaaacggaa aagcatttgt tattgacgga ggtctatcca
     1801 aagcttatca aaaaacaacc gggattgctg gctactcatt actatgcaat tcttacggtt
     1861 tccaaatcgt gacacattat ccgttcttgc ctattgaaca acaatttgca aaaaaatctg
     1921 atcaaacgaa tgtaaaaaaa gtgatcgagc agcagctccc acgcaaactt aatcggaata
     1981 cgacaaaagg aatggaatta cagcaacaga ttactcaact ccaaaggctg ttggattatc
     2041 gaaaggacga ttgagaaaaa tgctagccaa cattgctcaa tagactaaaa agcgactgca
     2101 acaaaaggcg tgtcgcagtc tccttcggaa ttagctcaaa aaacggtaaa atattagaag
     2161 ctatttttct gtttatttct ctaatactca ggtcagggcg ctgatttcac gacctcttcc
     2221 ttaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatatccaa caaacatgag
     2281 aagctgtttt ttgaaattgc tccttgtgac tcagagttga acggcaggct cacgacctaa
     2341 tcagaaaaac gattaaaatt cattcacaaa gaaatcgaat aaacgctgtt cagatgaatc
     2401 tacacgatga gaaagttccg gatgccattg gacaccaagg attttgtgca tattatcttt
     2461 actttggact gcttcaatga gtccatcgtt ggaaaaggcg atggctttta acaaaggaga
     2521 aagatctttg actgcctgat gatgatagga attcacaaag tatgaatcag ggagaaggtc
     2581 acttaataaa ctgtccgaaa cgattttgac ttcgtgagtt gcaaactgcg gggcagtggg
     2641 ctgttgttcg tgttttacgg accattttgg atataatgaa agatcttgat aaagtgttcc
     2701 ctccaacacg acattcaata gttgaagtcc tcggcagact gcaaaaatcg gttttctttg
     2761 tttcaatgct tccaagatca atgcctgttc gaattggtct cgttgaatat ttgtttccgt
     2821 cagttttgga tgagggtctt ccatgtaaag ttgcggacta acatcctgac cgcctgcaag
     2881 aatgagtttg tcgattttct caattagttg aggcgctgaa tctggagaca tgactggcag
     2941 aataagaggt aatccttgag catctaaaac tgcatccaca aatccctgcg gtgtatagct
     3001 tacttgattt ccttggaaag tatctgtcgc tcgaatcagt tgattcccgg caatgccgat
     3061 gattggtttc atttttattc cccctaaagt agactaattg taacaaggat ttaaaaaaat
     3121 ttaaactatg taagacttgc ccctatactt atctgttctt gctgtgttac tatctgtaaa
     3181 gagaattttc gtgtgaaatt catgacgata gttgaaaata ttgcttaatt tgttataata
     3241 aaaagtaagc agaaataaaa aggttgggcg taagcttcaa ggatctagtt cttcaagggg
     3301 tgagaaggac attttattga aggggcctgc ctatactaag ttatctttag aggtacatac
     3361 tttcaatgaa aaaagaaagc atgtacctct tttttaaatc gaaaggaagt gaagcaagtg
     3421 ttagaagctt tggaacaaat ccgaaaagca gaagaagaaa atgagaagcg tgctcgaacc
     3481 ctacggcagc agttgaagac ctatgcagaa gaaaaagagc aagaattgga gataatccaa
     3541 acgaacagtc ggcaacagct gaaacagttg gtagaagaaa aagaacaatt cgaaaagcaa
     3601 gaattagaaa aagaaaaaat gaaattgaaa gcagaagcag acaaggtgca agcaactttg
     3661 aaagaccaat atcaaaagca tcagagtcaa gcaatcggtg caatcattga aagggtgaaa
     3721 gaaacttatg gccgtcacta agatggaaaa agtgaccctc atttcagata aaagaaatca
     3781 ggagaggatt ttacaagcag tacaaggaat ccaaaatgtt gaaatccggg atctgtatca
     3841 aaatagaaca aacaaccagt gggtagaaaa atattttcca gataccacga ttattgataa
     3901 agaagcaaaa ttaagcgctt taggcaatcg gctgaaagac atccaagaag ctatccaatt
     3961 catacaacac cacggcgata gccgtcaaaa gaaactccat ttgaaacgtc aagaactttc
     4021 cttacaagac ttggaagcaa attattccga agaaaatttc atgaataaat tagaagaagt
     4081 ccttgattta aaagaaaagt gggaacagct aactgaaaaa cgtgatcgtt tagaagaaga
     4141 ggaagaatgg cttcttcatt ggcaacagct ggatattgct ccaagtatgt atgcaagtaa
     4201 gacgaccatt tttgagatgg ggactgtgag tgcagcaaat tttgaaagtt tcaaggaaga
     4261 actaagtaag cttgatgacg tttatatgga agaaatagat tatacgccaa aacaagttta
     4321 tctttcgtat gttgctttaa aaaaatcagt tgctgctata gaagaaattg ctgggaaata
     4381 cgggttcaat aaagaaacgt atccttatga acaaaatcct aaagaaaaat tgcaagaaac
     4441 caaacagcaa ttatccattg ttcacgagca gcaaaaaaag ataacgacag cgttaggtca
     4501 gtgcagcggc tatatccaag aatttgaatg ggtagaagaa gtcacacttg ccgttgcaga
     4561 acgggaaaaa gtaaaagaac ggtttatcca tgccacttat ctgatcgttt tgcaaggttg
     4621 ggtagatgca gaagaaaaac agaatttgat gcatgtgtta aacgaaactg tatcagaaga
     4681 agatatatac gttagtttcg aaacaccaaa ctcagaagag attcagcagg aagtccctac
     4741 taaattgaaa aaccatccgc ttatcgaacc ttttgaattg ctgactgaaa tgtacagtct
     4801 gccaaaatat gaagaagtag atccaacgcc ttggatgaca ccattttatc ttgtcttctt
     4861 cgggatgatg gtcgcagatg ttggttacgg attgctgatg ctcattggga caatactagc
     4921 tcaaaaacta tttgttttac cccgcgggat gaaacgtttc gtaaaattct ttgagattct
     4981 ctcggtacca tcgatcatct ggggattgat ctacagttca tttttcggac aggcattacc
     5041 aaaagaacta tttggtatcc gcttgccttt cccaatccta tctacgacgg atgacgtcaa
     5101 tacgattttg attttatccg tgattttcgg tctgatacag atcttggttg gattattcgt
     5161 ggcagcaaag gaaaatatca ggaggaaaga ttacttgagt gctgtcagtg atggttttgc
     5221 ctggcaaggg atcctgattg ggatcgttat tgcattgatt ggtgtcatgt tgataaaaaa
     5281 tacagcattt gtttatcttg gcgcggggct atcgatcatt gctgctttat gtatcttaat
     5341 cgtgccgatt atccaatcgc cgtctaaagt caagggtgct gccaaaggag cgtataatct
     5401 ttacggattg actggttata tcggtgattt agtcagttat acacgtttga tggcactagg
     5461 tatttcaggc ggaagtattg gcgcggcatt caatatgcta gttgctttca tgccgccagc
     5521 cgctcgattc agtgtaggga tccttttgat catcgcttta cacgcactga atatgttttt
     5581 gacactgtta agtgcctatg tccatggtgc acgattgcag tatgtcgaat tttttggaaa
     5641 attttataca ggaggcggac gtgcctttga cccgctgaaa acggcggaaa aatacgtcaa
     5701 catcaatcat aagaaaaaaa acaataaata attggaggat ttttatacaa tgatggatta
     5761 cttaattagt caaaatggtg gaatggtatt tgcagtatta gcgatggcaa cagcgacgat
     5821 tttttcaggg attggttcag ctaaaggtgt tggaatgaca ggtgaggcag cagcagcgtt
     5881 aacaacaagt caacccgaaa aattcggaca ggctttgatt ctgcaattgc ttccaggtac
     5941 gcaagggttg tatggattcg ttatcgcctt tttgattttt atcaacttag gaaatgatat
     6001 gtcagttgta caaggattga actttctagg cgcttctctg ccgattgctt ttacaggttt
     6061 gttttcaggt atcgcccaag ggaaagttgc agcagcaggt atccaaattt tagcgaaaaa
     6121 acctgaacat gctacaaaag gaatcatttt tgctgcgatg gttgaaacat atgcgatttt
     6181 aggtttcgtt atttccttcc tattagtatt gaatgcctaa gcataaagga ggaaaagcag
     6241 atgaacgcca ttgaaaaaat catctctcag atgaatgaag cagcagagca agaaagagcg
     6301 gcgttagagc aagaagagcg aatgaagatc gatcaaaact ttgaacaaaa acgtacgcaa
     6361 atcgaaacag aacatcaaaa acaaaaagaa aaacaaatcg aattacttga aaaaaaatac
     6421 cgtcagctta ggaatcgcca acaagtagaa gtacgacaag aaaatttgaa tgcgaagcag
     6481 gaatttttac gacgattgtt tgcagatgca atagctgaaa tggagaattg ggatgaatct
     6541 gaacaaatcc agtttatcaa aaattcattg tattcattac ctttgacagg caaagtaaca
     6601 ttcattgctg gagaaaaatc agcagcttat ctttctcaga cattgctgga tgaatggaac
     6661 aatgaacttc cctttatgat ggttttaagt gatgaaactg ttgctgatca agcgggtttt
     6721 ctgataaacg atcaaggagt tcagtataat tttcttttca gcagccttgt acaagatatc
     6781 caaggaacga tgagttttga gattgccaat caattattcg aataaggagg gatcagtgta
     6841 tggaatacca cgaactaaat cccttgattc gcggaagaga gcttgaactt ttgtccaatg
     6901 agacatttga acggatgatt caaacaaatt ctgtcgaagc acttggtgaa atattgaaat
     6961 ccacgattta cagtccatat atttatgacg gatatgaata tgacttcgaa cagaatcttt
     7021 taaaggagca gagccgtcta tttcgctggt taaaggaatc agcaccggag cctgaaatcg
     7081 tttggatcta tacgatgcgc tatactttcc ataatctgaa ggttttgaca aaagccgaga
     7141 tgacaaatca aaatctggac catttgtata tcgacgatgg attttattca ttagaaacct
     7201 tgaaggatgc cattcatacg caagtttcaa atgaactccc tgaaagcatt atggacagta
     7261 tacgagaagt acgtgattat tttgaagagt ctaccattct tcagggaatt gacgtgattt
     7321 atgatcgaca gtttttgaca gagcagcgac ggcttgccga taagctagga tatcaagaat
     7381 tgctgacaga agtcattgct tttattgact tgaccaatat cacaacgatg gctcgaggaa
     7441 tattgcagaa aagaacatat gggttcatga cgacggtact ttccagctcg ggaagtatcg
     7501 aaaaagaagt atttttgaac tttgtagata aagatatgga agattacacg aattttctat
     7561 tagagacaga ttatgctgat tttctgcgcc ctgtcatccg tgagggaaat cttgatctcg
     7621 taaagcttga acagttgaaa gatgattatc taagttcatt gtatcaagaa gcacaaaccc
     7681 aggctttcgg accactgcca ctactagcct ttttgaacgc aaaagaggta gaaagcaaaa
     7741 accttcgttt actggttatc ggcaaaagaa gccatttcga accagaaaca atcagaaagc
     7801 gggtgagaca agtctatgac gcataagatc ggtgtagttg gcgacaaaga ttctgttttg
     7861 ccattcaaat tgtttggctt tgatgttcgt tatggtacaa ccaagcaaac cgttcgtcag
     7921 gcaattgaag aaatggcaaa gaatgagtat ggcgtgattt atgtcacaga gcaatgtgca
     7981 gcattgagcc cagaaacgat cgaacgttac aaggaacaaa tgatacctgc tatcgtattg
     8041 attcccaatc atcaaggatc attagggata gggctggaag aaattcaaaa aaacgtagaa
     8101 aaagcagtag gtcaaaatat cttatagtat gaaaaggaga tagaaatttt gcaaattgga
     8161 aaaatcataa aagtctccgg acctcttgta atggctgaga acatgtctga tgccagtatc
     8221 caagacatgt gtctagtggg agatctagga gttatcggag aaattatcga gatgcgtggc
     8281 gatgtggcgt ctattcaagt atatgaagag acttctggaa ttggtccagg cgaaccggtt
     8341 cgctctactg gtgaagcttt atctgttgaa ttaggaccag ggatcatttc acaaatgttt
     8401 gacggaatcc aacggccatt agataccttt atggaaatca cacaaagtaa tttcttaggg
     8461 cgcggagttc aattgcccgc attggaccat gagaaaaaat ggtggttcga accaacagta
     8521 gaagccggag aaacggtgag tgctggagat gttatcggga tcgtagaaga aacaaaagtt
     8581 ataaaacata aaatcatggt gccaaatggg ataaaaggaa cgatcaaaac aatcgaaaaa
     8641 ggttcattca ctattgatga aacagtatgt gtcattgaaa ccgaaaatgg tgacaaaaat
     8701 ttgacgatgc ttcaaaaatg gccagtaaga cgtagtcggc caatcaaaga aaaattaaac
     8761 ccggatgcac ccatgatcac tggacagcga gtgattgata cattcttccc agtgacaaaa
     8821 ggaggagcag cagctgtacc tggtcctttt ggtgcaggga aaacagtcgt tcagcatcaa
     8881 attgcaaaat gggccgatgt ggacatggtt gtctatgtgg gatgtggcga gcgtggaaat
     8941 gagatgacgg atgttttaaa tgaattccct gaattgattg accctaatac aggagaatcg
     9001 ttgatggaac gtacggtatt gattgctaat acatcaaaca tgccagtagc agctcgagaa
     9061 gcttctatct atacgggaat cacaattgcg gaatatttcc gtgacatggg ttatgacgtt
     9121 gctatcatgg cagactccac ttcacgatgg gcagaagcac ttcgtgagat gagcggacgt
     9181 ttggaagaaa tgcctggtga tgaaggttat ccagcttatc ttggttcacg gcttgcggaa
     9241 tactatgaac gatctggaag agtcattgca ttaggatcag aaggtcgcga aggaagtata
     9301 accgcaatca gtgctgtatc cccgtctgga ggggatattt cggaaccagt cacacaaaat
     9361 acattgcggg tcgtaaaagt attctggggt cttgattcca gtttagccca aaaaagacat
     9421 tttccttcga tcgattggat acaaagctat tctctttatt caacagaagt agggaagtat
     9481 atggatcata tccttcaagc tgactgggca tccatggtca ccgagggcat gcgtattttg
     9541 caggaagaac agcagctgaa tgaaatcgtg cgtttggtag ggattgattc cctttcagat
     9601 aatgaccgtc tgacattaga agtggcaaaa tccattcgtg aagattattt gcagcaaaat
     9661 gcttttgatg atgtcgatac attcacttca agagagaaac aattcaaaat gttgaagatg
     9721 atcttgacct ttggtgaaga aggacgccgt gcgttgtcgt taggtgctta tttaagtgag
     9781 atcatggacg gtaccgtatc gattcgtgaa aggatcggac gaagcaaata tatcccggaa
     9841 acagaattag aaaaactaga tcaaattatt ggtgaaatca agcaaacgat gcaaacgatc
     9901 gtttcagaag gaggcatgag caatgattaa agaatatcgt acgatcggtg aagtcgtcgg
     9961 tccattgatg gcggttgaaa aagttgctgg tgtcaaatat gaagaattaa tcgaagtccg
    10021 tatgcaaaat ggcgagattc gtcgtggaca agtattggaa gtccaagaag ataaagcaat
    10081 ggtccaaata ttcgaaggaa caagtggtat caatttacgt gactcttctg tacgattttt
    10141 aggccatcct ttagaactag gtgtatcgga agacatgatc ggtcgagtat tcgatggttt
    10201 gggacgaccg aaagataacg gaccagagat cctgcctgaa aagcatttgg atattaacgg
    10261 agaagtaatc aatccagtag ctcgggatta tccagatgag tttatccaaa caggtatctc
    10321 tgcaatcgat catttgaata cattagttcg tgggcaaaaa ttaccagtat tttctggctc
    10381 tggtcttcct cataaagaat tagctgctca gatcgcgcga caagcaacgg tactcgattc
    10441 atcagatgat ttcgccgtag tctttgctgc tattggaatc acttttgaag aagctgaatt
    10501 tttcatggaa gattttcgtc aaacgggcgc aatcgaccgt tctgtcatgt ttatgaattt
    10561 agcaaacgac cctgcaatcg aacgtatcgc tactcctcgt atggctttga ctgctgcaga
    10621 atatcttgct tatgaaaagg gaatgcatgt tttggttatc atgacagaca tgaccaacta
    10681 tgcagaggca ttgcgagaga tttctgcagc acggcgagaa gttccaggaa gaagaggata
    10741 tcctgggtat ctttacacga acttagctac tttattcgaa cgagcaggaa gaatccgcgg
    10801 actaaaagga tcggttactc aaattccgat tctaacaatg ccagaagacg ataaaactca
    10861 tccaatccct gacttgactg gttatattac agaaggacag atcatcttga ctagagagct
    10921 ttacaagagt gggattcagc caccaattga tgtactcccg tctctttcgc ggttaaaaga
    10981 taagggaact ggacccggaa agacaagaga agaccatgca gctacgatga atcagctttt
    11041 tgcagcctat gcacaaggaa aacaggcaaa agaattagcc gtagttttag gtgaatctgc
    11101 tttatctgat gtagacaaga tctatgcgaa gtttgctgag cggtttgaaa aagaatatgt
    11161 caatcaagga ttctacacga accgttcgat tactgaaaca cttgatctag ggtgggaact
    11221 gctatcgatg ttgccaagaa ccgaattaaa acgaatcaaa gacgacatgc tggacaaata
    11281 tctgccagaa gggaagtgag ttctgatggc acgattgaat gtgaatccga cccgcatgga
    11341 attgactcga ttgaaaaaac agttgacaac tgccacaaga gggcataaat tattaaaaga
    11401 taagcaagat gaactgatgc gtcaattcat cctgttgatt cgaaagaaca accagctgcg
    11461 tcaagaaatg gaagagtcta tgacagaagc aatgtctgat tttgtattgg caaatgcttc
    11521 gatcacggaa cctttcatcg aagaattatt tgttttgccg gcggaaaacg ttgatttgtc
    11581 tatcgtagac aaaaatatca tgagtgtaaa agtacctgtg atgaattttg aatatgatga
    11641 acagctgaca gacacacctt tggaatacgg gtatttgaat tccagtgccg aactggatcg
    11701 gtcaatcgat cggtttacta ccctgcttcc aaaacttttg gaactgacag aaatcgaaaa
    11761 aacttgtcaa ctgatggcga gtgaaatcga aaagacacgt cggcgagtca atgcattaga
    11821 atatatgacg atccctcaat tagaagaaac gatctattat attcgtatga agctggaaga
    11881 aaacgagcgc gcagaagtaa caaggttgat caaagtaaaa aatatgggta ccactgacta
    11941 agtggtatct ttttttaaaa gaggaaaacg atgattaaac aaagcaaaca aataaagaaa
    12001 cgtttgccgg ctgttcagct tctcgcatta ggattttttc tcctgatttt agttggcggc
    12061 ggcctactta ccctaccatt ttttagtaat agtgggcatg ggacaaattt tatcgatgcg
    12121 cttttcactg caacttctgc tgtctgtgta acgggattga caacattgaa tacagcagag
    12181 cattggaaca gtgctggtca atttttgatc atgcttttga ttgagatcgg cggtcttggt
    12241 tttatgatgg ttccgattct atgctttgca ttgataaaga agaaagtcag tctcagcaca
    12301 cgtattatat taaaagaagc gctgaatcta gaagaagtat caggtgtgat gaagctcatg
    12361 ctttacatcc taaaattggc ctttgttatc caattgattg gtacggttgc tttatctttt
    12421 gtatttgtgc ctgaatttgg ctggttgaaa ggtatctggt acagtttgtt ccatgcaatc
    12481 tctagttttt gtaatgcagg gtttgatttg ttaggagaca gtttagccaa tcaccagcaa
    12541 aatgtttatt tgatcatggt ggtatctgct ttgatcattt ctggtgggtt aggcttcatc
    12601 gtatggcgtg atttactgga atatcatcag aaaaagaaga tgacgattca ttcaaaaatc
    12661 gcattaaccg ttacaggtac ccttttatta ggcggattcg ttgtgttctt tttcacagag
    12721 cgcaatgggg caacgctagt ggaagggaat atgtttcaac gattggcaaa cacctttttt
    12781 atgagtgtga cacctagaac ggctggatat tattcagttg attacctcca tatgagccat
    12841 gcaggtctga ttttaacgat gtttttgatg tacatcggcg gaacatctgg gtcgacggcc
    12901 ggcggattga aaacaactac gttaggtgtg ttgctgatcc agatgcgttc gatgttgaaa
    12961 ggacgtacga gagcggaagc atttggccgt accatccgac aaggcgcagt gttgcgggca
    13021 cttactttat tttttgttac gttgacgttg tgtgtagtcg ccatcatgat tttatcggtg
    13081 actgaaacga tacctaaaac ttctggcatc gaatatattg cttttgaggt cttctctgcg
    13141 tttggtacag taggtcttac gatgggattg acgccagact tgactgcaat agggaaattg
    13201 atcattatag cgcttatgta cattggacga gttggtgtat tgactgtggt cttctctctg
    13261 atgacaaaag cacaaagaac acaatcaaaa tacaaatatc cagaagaaag tgtcatgatt
    13321 ggataatttc atcttctgac agaaacctag tgatttagta aaataagaaa ataaaataat
    13381 ttttcttgct tcttggatac tttaagtgca aaatgttcgt ttattttttg aggcactacc
    13441 cgttgttgaa cctcgggtag tgcctctttt ttattgaaag gaatcaataa gatttgattc
    13501 ctttatttat caataggtta taattcatat ttttttattt tttcttttac gatacttagt
    13561 ccagaagcta aaatttcaag gttattagag gatagggaaa ttcgaacgaa tgcatctggt
    13621 tgcgcacgtg tagtaaagcg tctggaatga taaagtcgga taccgttagc aagaaagtca
    13681 ttctcaatta tcttagggtc aatctcagga tcaactggaa gaattcgata gtaagggaca
    13741 cgattcgttg gtttttctac tttgaaaaga gaatcaaaaa gctgattggc tctttttgta
    13801 agacttaatt tagtttctaa gatcctattt gcttcatttg aatggaggat ttgagtgatg
    13861 acttccacat ctaatccaga agttttcaca tttatattaa aaattgcttg ttctatcttg
    13921 ctttggacat gtactggaac tacaagataa gcaactcgca atccagaaca aataaatttt
    13981 gtcattccag ctaagtagat tgtttggtta ggtaataaat tttggaaagg aggaatgatc
    14041 gtatgttgat agtaagttgt taaaaatgaa tggatatcat cttcaataac ccatagacct
    14101 tctttttcaa tcacttcggc taattgctct cgtcttttgt gagagatttg aaaccctata
    14161 ggattattac aagaaggcat aagaaagaca ccatgaatct tcttttttct acattcctga
    14221 atcaatatat caggtcgcat tccttgctcg tcaaaatcaa ttggaacgat ctctaaatga
    14281 tataactgag ccaattcaat gaaattagcg tatgtatatc ggtctgttgc tattctatca
    14341 cctggagaga aaagtgcaga aagtgtgata gccaatccat tttgaacacc ggaaacaata
    14401 gatagagatt ctaaggacgg aatgactcct tgagttttta accaatttgc tgcagtagtc
    14461 aattgaaaat ttgtgccttt gggatcttgg taattaagca aaccaacaag atttgggtta
    14521 ttactagttg attgaataaa cgggacaacg aatttattac attcttcaaa agaactaacc
    14581 agaccaaaat caatgatatg ttcggttact tcattggtag agatggtgat ggactcaaag
    14641 acattgggag aaataaatgt gccacttcca atattcgtat acagcaaacc tttctcaatt
    14701 ccatatttat aagccttgcc aacggtagta aaatttaaat ctaaataatc agctagctct
    14761 ctttgggagg gtaactgagt gtttttctgt aatttattct ttaaaatatc ttgttctaat
    14821 tgttgaatca acgatcgata ataaggacgc ttcaattttt gtttgtctgg tcgccaagtt
    14881 aacgggtaat tgtcataaga attaataggc attttctcca ctccttaaaa ttgtatacca
    14941 tacaatttta ccattgattg tattgatttt agaagttaat cttttgtgag gagggaattg
    15001 tctatgaaaa ttattaattt tgaggaagta gtagcttctt ttagttttga agaagcgatt
    15061 caagtaatga aaaaatgttt ttttgattat gaaagtggta aaatcagcca aaatcctcga
    15121 ttggtggaaa ttttacctga cggaaaaggc aaaaatatgt ttgcgatgat gcctgcttat
    15181 ttgggggaga acagatattt tggcacaaaa gtcattaccg cttttccgga taatcatcag
    15241 tatcatttac cttctcattt aggagagatt ttcttgtttg atgctcaaaa cggactaccc
    15301 aaagcattga taaacgcaaa tgcagtcacc tggattcgaa cagctgctgt atctgcgctg
    15361 gcaacagatt acttagcaaa tccgcatgca gaaacacttg ctttaattgg agctggtcaa
    15421 caagcattgt cgcatttgac tgcgatttct accattcgtc ccatcactac agtgtttgtt
    15481 tacgatattt tagaagaaag acgaaatact tttatcgcta aagctaaaaa acagtatcct
    15541 aaaataacgt ttataaatgc aatatcagta gaagatgcag tacgtccagc ggaaatcatt
    15601 tgtacgttga cctctagtaa agaggcattt cttcaaaaag agtgggtaag ggaagacgca
    15661 catatcaatg ctgtgggcac atttactcct gatacaagag agataagtac atcgttgatg
    15721 gaaacttctc aaatctatgt agatgattac tcagctgcct taacagaaag cggggacctg
    15781 cttatagcca tggcagaagg agatttagag gaatcttgta ttgttggtac attaggcgaa
    15841 ttagtttctg agaaaaaaac attttataaa ggagaatcga ggccgacgat tttcgacgca
    15901 gttggtctag ctattgaaga tctttgttgt gcagaatata tttataacaa attagagaaa
    15961 ggggctttaa aatgaactta gattattacg tagttgatgc atttgcagat gaggtgttca
    16021 aaggaaatcc agcagcggtt tatgtgctag aagaatggct gccagaaggt acgatgcaaa
    16081 aaattgccat tgaaaacaat ttatctgaaa cagcatttac agtgaagaaa aaccaagaat
    16141 ttgagcttag atggtttacg ccagatcgag aaatcgatct ttgtggtcac gcgacattag
    16201 caacagcatt tgttttattt aactattaca aaatacctga tgaaacgatt aaattttcta
    16261 ctcaaagcgg taatctattt gtgacaagaa ttaaagatta ttattacatg gattttccta
    16321 gtattatgcc gaaaaaagtg ccgatattgt ctgaatatga agaagcgatt ggggctaaga
    16381 ttaaagaagc ctacttagca cgtgatttat ttttcgtatt agaagatgaa aaaacggtgg
    16441 ctaaattgca gccagatttt acagctatca aaaattttga attaggaata ggagtcatcg
    16501 tgacagcaga aagtgtgcaa aaagactttg tttctagaac cttctttcca aaattaacaa
    16561 tcaatgaaga tccagtatgt ggatcagcac attctaatct tattccttat tgggcagaaa
    16621 gaatgaataa aacaaaattg tcagcttatc aaatgtcatc aaggggcggg gatctagaat
    16681 gtgaattaaa agaagatcgt gtgataatag gaggaaaagc agttttgttt tctaaaggta
    16741 cctcgtttat ttgatttctt tcaaatgaat taaaaataaa ttggtggaga gtggcaacct
    16801 tatagctaca atggttgtta aaaaaagacg caaacttttt caatttaatg aaaagtttgc
    16861 gtctcatttt aattattggt gtttgttttt tattcaatca agagtaaaat gccccatact
    16921 aactatcctc ggatgacttc gattttataa ccatcagggt caatgacaaa gtagtaagaa
    16981 ggcgcagtgc caggtaatcc ttttaagtca gtaatctcaa gaccggcagc tttatgttgc
    17041 tcgtgtaatt tttctagatc atcagctgct atagcgatat gaccatagcc gtctcctaga
    17101 tcatacgcac catgatcata gttgtaagtc aactctaatt catagtcatc cccaggaagt
    17161 gtcaaataaa caagtgtaaa tttgttttct ggaaaatcac ggcggcggct ttcttcaaaa
    17221 ccaaatgcct tttgataaaa ttcgattgat gcttcaagat ctttcactcg aacacatgtg
    17281 tgagccattt tcatagattc atctctcctt ttccttttac tcaatcataa caaaaagaag
    17341 taaggaaata gttgatttgt gcttgttcat gagaaatttc tcatgtaaaa tggatagaaa
    17401 ataaaactgt taaggtggaa actattcatg gataaaccaa tttttggtga aaaaaagcaa
    17461 tttgctgatt atcaaacccg ttatgcagca tatattgtca tagaaagaga tcagcagatt
    17521 gcagtaatcg aggctccaaa tggtgctttt tttcttcctg gcggggaaat tgaaggagaa
    17581 gagacgaaag aagaagcgat tgtccgtgag ctgatagaag aaatgggaat tgtggcagaa
    17641 atttcttctt atctgggaga agctgatgag tatttttact cgaattatcg tgcaacttat
    17701 tattataatc caggatattt ctttgttgct gattcttgga agcgtatagg agaaccaact
    17761 gaaaagacca ataaaatttg gtgggtgagc cctcaagaag cgcttgtgaa attgaaacgt
    17821 ggtagccacc gatgggcagt cgagagatgg atcgaaaaaa ataaaaactg aaagaaagcg
    17881 agtagatcag ctttctctca gtttttttat ttattacagt acatattttt tgattgcttc
    17941 agctacaccg tgctcgtcgt ttgatgaagt gatgacattt gctgcttctt tgacaagaga
    18001 aacggcattt cccattgcta ctcctagacc agcatattca atcatggata agtcgttctc
    18061 gttatctccg atagccatga tttcatcttg atcaatacca aggtgctgtg cgagattcgc
    18121 aactgccgca cctttacttg cttctttatt tagtacttcg aagtaatagg gcgcactttt
    18181 gaccgttgtg tatttatcac ggaaagtttg cggtaaacgc gcaattgctg catctaaaat
    18241 ttctggttcg tcgatcatca tcattttgac gatgttcatg tctggtgtca tttcttcagg
    18301 tgttcgatat tttagcggca tcttgactaa acttgcttcg tggatcgtat aagcgctgat
    18361 atctcgatta ggcgtgtaga tcgctttgtc atcgatcgaa tggagatgac tgccgacacg
    18421 gcgtgccatc acttcgatct ctaggaaatc ttcatgtgtc agtccgtgac gggcgatgat
    18481 tttacctgat ttcgtttgtt gtacgagtgc cccgttataa gtaataacgt aatcattatc
    18541 ttgaaaaagg ttcaactcgt ttaactgttc ctggacacct ggtaagggac ggccagtgca
    18601 taaaacgatc gaaacacctt ttgcaacagc agcggcaatc gcttctttta cttcttttgt
    18661 tacttctctt ttctcattta ataaagtacc atcgatgtcg atagcgacta gtttgataga
    18721 cataatttcc tccaatatat tttaatttat ttcaatcaat gcgccattac ggatatggct
    18781 ggcaaattct tgataagttt cgtcaaataa atcataatga tcacgcaagg acggatcaac
    18841 catttctttt ggaaagaaaa atcgctcatc tccttgttct tgtcccgcta atgcagcaac
    18901 aagctgacta acctgtgata attctatcaa agttccgtca tttcgcaaaa tctcgatttg
    18961 tgtgcgatgt ctgccttgtt ctgggcgata aaaatcataa ggtagatcgt agctagaatt
    19021 cacagcagtg taataaacag gattatatcc gaccttttct actaacaaag tgagttcttg
    19081 gactaatttt gaatcccggt tgccagaaaa agtagcagat ttcagtggtt tacgattcaa
    19141 aaaacgttta gctaaatcat ttaaaatagg atcagcagat tcagaccatt gagtaaagta
    19201 agtgcccaag accccatcat caagtttgag gtattcttct aaagtaaagc ttccgtcaag
    19261 aaatggcaga agtaattgag aatggagttc aaaactgctg gcatcttctt gatacaactc
    19321 gtgtgcgcga tgaagcagat gctccaaaat tacttccata ccacgggaaa caggatggaa
    19381 gtacacttgc acatacattt gatatcggct aacgatataa tcttccactg catgcatgcc
    19441 actcatggaa aaagcgatcc cgccttcata aggacgaatc acacgtaata ttcgggtaag
    19501 atcaaatgtt ccatattctg ttccagtgaa ataagcatcc cgaagcaaat agtccattcg
    19561 atctgcatcg atctgactag aaatcatttg gacaacttgt gggttggggt aagttttttg
    19621 gatcacacta gctacctttt caggaaaacc ttcttctact cggttaagaa tctgatacac
    19681 ttctgtttct ggagaagtga tgatctctac agtgatggct tcatgattcg tatggaagat
    19741 atgttcaaat gtatgagagt aaggaccatg accgacatca tgcaacagtg ccgcacataa
    19801 agtcaccagc cgttcctgat catcccagcc tccgttgcct attttttctt ttgaaaaatt
    19861 tcgagaaaag atatcgcaga ttcgtcttga aatctcataa acgcctaatg aatgagtaaa
    19921 acggctatgt tctgctccgt gaaaagtgaa agaagaagtg cctaattgtt taatgcgtcg
    19981 tagacgttgg acttctttcg aattgatcaa atctaagatt acttgatgct ggacatggat
    20041 atagttatgg actggatcac gaaaaacttt ttccataggc agcatttgat atttataagg
    20101 ggttgtcata atgtagctcc tttatgttat tacgttgttc cattctctgg atttggttgt
    20161 tccattgctc cagctggatt tcttttttta gccagtcggt agaatcctgt aaatcacttg
    20221 cagaatacag cttttcaaaa gcttttgcaa atgcttcttt gacttctttt acaaaaaggg
    20281 gttggtcaag cagttcttca agtgttgcca ttgtagcagg atccactgca ggatagccat
    20341 ttgtaccaaa gtcttctttt aaagcagatt gataaaatcg cttcatgact tgcccgcgtt
    20401 tttcctgatt accgttgaca cttaagtaca tcataacaga aatcccattt ttgatccgac
    20461 gctgagcgat accggcaaat tttttgccat ggatgcttaa atcataagtt ccaggacaat
    20521 aagaatgggt gatttcgaat gcttgtatcg gtgcctttgg aaaagcgtat ttagtcaata
    20581 ggagcatttg ctcgtaagcg tcatctatgg ttattttttt tgtgtcactt tgggggaaaa
    20641 tcaaagaaat attcaaaatt ccttcatctg atacgatccc taatccacct gaatttctga
    20701 tcactggagc gtaacctgca tctttcagtg tttggatccc gtcacttaga aaaggagttc
    20761 gaacatcctt catacctaag atgactgtgc agtcatattg ccagaaatgt aaaaagattt
    20821 gctggtgttc tttagaatat tccgttaata tatctgttaa tgcaaaaggg gaaaagtcgt
    20881 ttttttgata aatgtgctga tctagtcgaa tcgcagggtt cattcaaccg gctcctttgt
    20941 ataaattcat attttctaca atattatact ctaaaatcaa agagttgttt tggaaaaaag
    21001 gttttctgta aaaatggaca agttggttga caaaacaaaa gaaactagga acaatgtagc
    21061 tatgagaagt aaaggagaat gaataatgga attatcacaa ggaacaccga tttcaatcaa
    21121 attgcgtaca aaagtaaaac agcaagggga agtgcaagat ttttattttg atttgaaagg
    21181 gcaaatggtg acaattggcg atacgctgta catacgttat aaagagattc aggaggagac
    21241 gggcgatgag attcctgtaa cgatcaaatt agttccagat ggtcatgtac agctgatccg
    21301 tgcaggagaa atgcggatgc gtttgaaatt tggctataaa gaacggttag aaacatccta
    21361 tcgaacacca tacggtatga tccagattgc tacttttacg aaagaactgc atgttagttt
    21421 gaaagaccgt cccacaggag ggaaggttcg aatcgattat gatctgttca tgggaccgga
    21481 aaaaatcggc gaatattatt tgaccttgga ttttacagcg taaatataaa agaaaagttt
    21541 gattttttgt gtctgatttt gtatgataag gagtagactg tgaaaggacg tgtcctgatt
    21601 ggaaattagt gtatttgaag gtgcaaacaa aagcgaatta tcaatgatcg aagtagcaca
    21661 cgcgatctta gaacaacgtg gcgatgtcat ggatttttct gatttagcta accagatcca
    21721 aaactatctt gggaaatcag acagtgaaat tcgtgattca ctcgcacaat tttatactga
    21781 cttgaatatt gacggcagct ttatctcatt aggggataat cgttggggct tgcgttcatg
    21841 gtatgctatc gattcgatcg atgaagaagt aaaccatgga atggacgaag aggatgaaga
    21901 tactccacgt cgccgtaaac gcaagaaagt caacgccttt atcaatgatg atgaagacgc
    21961 gatcgattac aatgacgatg acccagaaga tacagatctg acagaagaag atgacgatga
    22021 tctgtttgat gacgatgatg atgaagatga agaaatcgct gcttataatt ctgacttgca
    22081 agaaatcgga gcagatgacc cgacagatga tgaagaagac ttgccaggaa atatcgaaga
    22141 agatttaagt atcatagacg aagacgatga tgatgaagat tatgaagagg aagaattttc
    22201 tgactctgaa aaagaataaa cattattttc ttacgagagg ttgtgacaga gacgatcagc
    22261 ctatcagaat aaggaggtgt gacacgattt ttgtcacacc ttcttttttg tatataaaaa
    22321 tcccaagtaa atacataaaa aataaaaaaa ttgaaacttt tagcgcacct tgtacgtcat
    22381 attaagtgag gcagaaagga gtggagaatg atttttactg gatataagaa aaaacggcag
    22441 atcgaaaaat accgtcacct gctgaatgga ctcatcgaaa ctgattatca aaaaatgttc
    22501 cgtatcacga tgaattacgt acatgataaa gaagaggcct tagatgtgat gcaagatagt
    22561 tttcataaag ccctgaacta ttttgaaaaa gaaaaagaga tcgagcattt tagtgcatgg
    22621 ttttatcgga tattgatccg cacggcatta gatagttggc gcagacaaaa aaggacgcct
    22681 gtggacttat ttgaaattca agatatcccc caacagttac ctttagaaac ttccgttgca
    22741 gagctccata tgattttaga taaaatagac agtccggaaa aagagattct gatcctctac
    22801 ttttttgaag gatttcgttt gaaagaaatt gcgactatct tggatatgaa tgaaaacaca
    22861 gttaaaacga aaatgtaccg ctcattgaat gctttacgtc aaatcctaga atgaaggaga
    22921 gaagagtgcc atgtattccc aaaaagaaaa tttaaaaaaa ctaaagaaaa cttataaaga
    22981 acaagcaatt cccaaagggc ttaaagagga gatccgccag cgttttatta tcgaagagca
    23041 atcatttata aaagcaaagc ggagaaagag acgtctccaa gggttcggag tatctttggc
    23101 tatcgtaatg attacaacaa gtagccttct ttttaatagt caagttcgaa gctttgcaga
    23161 agatttaccc atcttaggat cagtcattga attgatctta ggcgaacgct ttactgatcg
    23221 atctgaaaaa atcgatattc aggtaccgaa gatcaataca caaaatgaga aagaaaataa
    23281 aacaattcat ggattaaatc aaaaatactt tcgcgaagga caagcagatt ttgaaaaagc
    23341 tgaaaaagaa tatggaaatt ttgaaacgga tcattaccaa gttttgggag attatcagaa
    23401 aatcgtagac gataaccggt ttctcgtgat tgaaaggcag atcacccaaa cagcagcaga
    23461 tagccatgtt gaaaaaagat acgacacaat cgacaagaaa aacagtgtcc agctctcact
    23521 tccactttta ttcaaagatg acacctatct atctgttttg acaaaagaag tcaaacggca
    23581 gatggccgaa caagtcaagg aagatccatc taagtactat tggactgagc aagatattca
    23641 agaagggacg atagaaaaac caacacttgt tacgcctaca cgaagttttt atttgaacaa
    23701 agagcatcaa ttagttttga ctttttctca atacgaaatt gctcctggtt atatgggtac
    23761 accagaattt gtcattccta agtccgtgac aaaaacgatt ttggcatcgg aagattattt
    23821 ggatcattag acgagaagta gttgcgacta gcagtttcaa ttttcaagta agtacaagta
    23881 aataataaga agagaaaaag agaaagaaga gatatagtga aaagaaatta tttagttatc
    23941 agtattattg ctttatccgt gcttttgttt ttcgaaatta cttcggtggc ctccttgatc
    24001 accgaagtaa aaggacaaac acactcttcg gagcattcgt cacaatcttt caaacaatca
    24061 gaacaatcaa ccattaaaag ccaatcaact gaaacagcta acgtcaaaga agccattcaa
    24121 gaatcagcgg aaaaggtaca aagtcagtca tcacaatcaa cacaagacag tacaaaaacg
    24181 agccgagatc cggctgtcaa aagcgtcgca atcagctttg atgatggacc aggagcgacc
    24241 acaacaccgc agcttctgcg aatcttaaaa gaaaaaaacg tgcatgccac ttttttcgtc
    24301 ttaggagaaa atacggcgca gcatcctgaa atcgtgaagc agacagctga agcagggcac
    24361 gagattggca attacacata cgatcatcag aatctggcca ctctttctgc ccagtcgatg
    24421 acggaggaag tgacgaaagc agacactgag atcaaaaaag tcactggcaa aacccccact
    24481 tttgttcgtc cgccctatgg ttctgtcacg aatgtaggag caacgatcat ccagcgaccg
    24541 atcatcgaat ggtctgttga ttcagaagat tggaagacaa gaaatcctga tttgattttg
    24601 cagaagatcc aagcaacagt atacgatggg gcaattattt tattccatga tatctatcct
    24661 gaaacgattc gtgccgttcc tcaagtgatc gattatctga aagagcaagg gtatcgcatc
    24721 acgacagttg gggatttatt agggcatcca acggctgtcg agaactatta tggcagaaac
    24781 gatcatcggc cagttcagta agtgagacaa gtatctttaa taaataacac attttaataa
    24841 gtagttgaac acataactac cttacttgca aaggcttaac aatatctata caggtacaac
    24901 aaaaaactgt ccaccaattt tctttggcgg acagttttca cttaaaaata aagaagcaac
    24961 tattcgtaaa ttatgctaaa atagcagtag aacgcgtcct gagggaatcg aacccccgtc
    25021 tcaagaaccg gaatcttacg tgatatccac tacactaagg acgcaagcac tgggataatt
    25081 gtaactaaac agataaaaaa ttacaagggg attggacaaa aaaatgaaat ttgagcaaaa
    25141 tttttcacaa aaacagcagc agacacagaa actagccatg acgcaacagt tgcaacagtc
    25201 catccaagtt ttacaatata acagtgagga gctgttggca ttcgttgaga atcaagcaat
    25261 ggaaaatcca ttggtggaag ttgttgagcc ggaatggcag ccagattaca taaaagcttc
    25321 ttcatcttct tatgaaggag aagagacaaa ttacctaaat cagattcctg atacaaaagg
    25381 gtctttattt gattcattga tcgaacaagt ccatttgaat taccgagata cttttttgag
    25441 gaaaatcgtt ctttatcttg tagaatacat cgatttgaac ggatttttga cgattagttt
    25501 agaagaagcc ggaaaagaga ttggagctac gcctatccaa atgctcgatg cgttgactct
    25561 gattcagcaa ttagaaccag ctggagtagg tgcacgtagt ttgcaagaat gtctcatgct
    25621 tcaaacagaa cgagatgatt atgcgccgga attagcttat atcgtgttgg aagaatgttt
    25681 tgaggaactg gtggagcgaa aatggaaaga aatcgcacaa cgtttttctg ttgatctaca
    25741 tgctgttcag cagatattcg actatttaca aacgttgagt ccaagccctg gccggatttt
    25801 cgaccgtagc agcgaattgt acattattcc tgatgtccgg gtattagtgg acgacgataa
    25861 aaatgtacaa gttatctcaa accgaaaaaa tcagccaaat atacgctttc aagagagtta
    25921 cttcaaacaa atgtcacaac aagcagataa agaaactgaa aattatttaa aagaacggaa
    25981 acaggaattc gaatggttga agaaaacgat cctacaacgt ggggatacaa ttttgcgggt
    26041 tgctcaagtc attgtttccc ggcaaaaagc tttctttatc gacaaggaac gtccaatcaa
    26101 gcctcttacg ttaaaggaag ttgcaactga gatagatgtg catgaatcca cggtcagtcg
    26161 tgcagtcaac gggaaatatt tggaaacaga tttcggtgta tttgaattaa aaaaattttt
    26221 cactacacga attcctacga atagtacaga acagacagaa gacctttcag cagatacagc
    26281 gaagaaaaag ctgcaggaat tagtcgatca agaagacaaa aacaagccgt tgtcggacca
    26341 gaaattggtt gaattgctga aaaaagatga gatagcgatc tcaagacgaa cagtagcaaa
    26401 atatcgtgat ttattaggaa tcccgagttc atcaaaaaga aaacgttatg ataactaatc
    26461 agtcaaaaga ctagaaaaag tatttcactt tttctagtct ttttagttga aaaacgagag
    26521 cgaaactgtt agacttacag tcgtgaggtt gagatttccc tttattgatg tgaaattcga
    26581 atagttaatt tcttttttta tcgtatatgg gtcgttttaa gtctacattg gacgtaaagt
    26641 gtccaactaa ggagatcgct atgctggatg aaataaaaat gattgaatct gttgcaccag
    26701 atattatcga agtgttgcaa gaacgctata aaattttacg aaatatctat tggatgcagc
    26761 cgattgggcg tcgaagttta tcggaaagta tggggatcac agaacgagtc ttacgaacag
    26821 aaacagacct tttgaaaaat ctgaatttga tcgacacctc aaaaagcggt atgacgctga
    26881 caactaaggg cgaagaagtt tatcaaagcc ttgaaaactt catggatcag cttttaggta
    26941 cgcatcaaac cgaacaacag ttggcagaat attttggtaa ccaacgctgt atcgttgttt
    27001 caggaaacag cgaagagcag accaaagtgg ctgatgcatt cggcgaagcg ctgagcgaag
    27061 ccttagaccg actacttcca gaaggcgaga atatcatcgc tgtgatggga ggaactacta
    27121 tggctgtggt agccgaacaa ttgtctaatc tggaaaataa gaaacggcat aacctgtttg
    27181 tccctgcaag aggcgggatt ggtgaagcga taactgtaca ggcaaattct gtcagtgcaa
    27241 gaatggctgc taaagcaaac ggtaaccacc gcgcacttta tgttccggaa caattaagtc
    27301 tggcaactta caattcttta ctcaatgagc catctatcca agaagtctta aacttgatta
    27361 gtgaagcgaa ttgtgttatt catagtattg ggcgtgcatt acacatggca gcacgtcgta
    27421 agatgactga aaaagaatta gtcatgctga aacaagcaaa tgctgttgcg gaatcttttg
    27481 gctacttttt caatgaaaaa ggtgaagtcg tttataaggt ccctagaatc ggcatagaat
    27541 tgcaagattt ggaaaaagtc ccgatcatca tggcaatcgc gggcggaaaa tcaaaagcta
    27601 aagcaattcg agcttatatg aaaaatgcac caaaacaaac gtggctcatc actgatgaag
    27661 ctgctgcaaa tgagatttta aaaggggtaa ccctttaaaa taaatatttt tttgattttc
    27721 ataaggagga aatcttaaat gacagttaaa gtaggtatta atggttttgg acgtattgga
    27781 cgtctagcat tccgtcgtat ccaagatgta gatggaatcg aagtagtagc aatcaacgac
    27841 ttgacagatg ctaaaatgtt ggcacacttg ttaaaatacg acacaactca aggacgtttc
    27901 aacggaacag ttgaagttca tgaaggttca ttcaacgtaa acggaaaaga agttaaagta
    27961 ttagctaacc gcaacccaga agaattacca tggggcgaac taggcgtaga tatcgttcta
    28021 gaatgtactg gtttcttcac ttctaaatca gcagctgaaa aacatttaac agctggtgct
    28081 aaacgcgttg ttatctctgc tcctggcgga aacgatgttc caacaatcgt ttataacaca
    28141 aaccacgaaa cattaactgg taaagaaaca gttatctcag gtgcttcatg tactactaac
    28201 tgtttagctc ctatggctaa aacattgaac gacaaatttg gtgttgttga aggattaatg
    28261 acaactatcc acgcttacac aggtgaccaa atgactctag acggacctca tcctaaaggt
    28321 gacttccgcc gtgcacgcgc tgctgctgca aacatcgttc ctaactcaac aggtgctgct
    28381 aaagctatcg gtttagtaat tcccgaattg aacggtaaat tagacggagc tgctcaacgt
    28441 gttcctgtac caacaggttc attaacagaa ttagtaacag ttcttgaaaa agaagtaact
    28501 gttgacgaaa tcaatgcagc aatgaaagaa gcttcaaacg aatcttacgg atacaacaca
    28561 gacgaaatcg tttcttcaga tatcgttggt atgacttacg gttcattatt tgatgctaca
    28621 caaactaaag taatgacagt tggcgacaaa caattagtta aaactgttgc ttggtacgac
    28681 aacgaaatgt catacactgc acaattagta cgtactttag aatacttcgc taacttataa
    28741 gatagacaaa cgtacaagtg taaattatag acatgtacat ttaaaagcgg ggaagcaatc
    28801 gcgcttcttc cgcttttttt gataataagt ttattcagga ggaaataaaa tggctaagaa
    28861 aacagtgaaa gatatcgatt taaaagacaa aaaagttctt gtccgtgttg acttcaacgt
    28921 tcctttgaaa gacggcgtga tcactgacga cactcgtatc aaagcagcat tgccaacaat
    28981 caactacgtt ctagaacaag gcggaaaagc aatccttttc tctcaccttg gacgtgtaaa
    29041 aacagaagaa gataaagaag gaaaatcttt agctccagtt gcaaaacgtc taggcgaatt
    29101 attaggtaaa gaagtaacat tcgtacctga aactcgcgga gaacaattag aagaagcaat
    29161 ccgcaacatg aatgacggcg acgttgtcgt attcgaaaat acacgatttg aagatattga
    29221 cggtaaaaaa gaaagcaaaa atgatacaga actaggtaaa tactgggctt cattaggcga
    29281 tgtatttgtt aacgatgctt tcggtacagc tcaccgtgca catgcttcta acgtaggtat
    29341 cgcttcaact ggtatcccaa cagttgctgg attcttgatg gaaaaagaaa tcaagttcat
    29401 cggtgaagca gtagaagaac caaaacgacc aatgattgca atccttggtg gcgcaaaagt
    29461 ttctgataaa atcggcgtaa tcgaaaactt gattcctaaa gcagataaaa tcttgatcgg
    29521 tggcggaatg acttacacat tctacgaagc aaaaggaatc aagatcggta actctctagt
    29581 agaagctgat aaagtggaac tagcaaaaga attaatcgaa aaagcaggcg acaaacttgt
    29641 cttgccaatc gacaatgtct gtgcaccaga attttcaaat gatgttgaaa cacaagtaat
    29701 cgaaggagac attcctgatg gtttgatggc tttagacatc ggcccagcat cagtaaaatt
    29761 atttgctgat acattacaag gtgcaaaaac agttgtttgg aacggaccta tgggtgtatt
    29821 tgaaatgagt aactttgcta aaggtacaat cggtgtttgt gaagcaatcg ctaacttaga
    29881 aggcgcaaca acaatcatcg gtggcggaga ctcagccgca gcagcagaac aattaggatt
    29941 tgctgacaaa ttcacacaca tctcaacagg tggcggcgca agcttggaat tgcttgaagg
    30001 taaagaatta ccaggactag cagcaatcaa cgataaataa acgaccaagt ttgctcaatt
    30061 ctgacgagta atcgaacaaa aggtgaaggg agttttcatg actccctagc catttttcaa
    30121 taaattaagg agtgtgttcc tcaatgcgta aacctattat cgcaggtaac tggaaaatga
    30181 acaaaactgc atcagaagca aaagaatttg ctgaagcagt aaaaaacaaa atcccttcaa
    30241 atgacaaagt tgattcagtc atcggatctc ctgcattatt cttacaagaa ttaatgacat
    30301 cagctgaagg tacagaacta aaaatctcag cacaaaactg ctactgggaa aactcaggtg
    30361 cgttcactgg tgaaacttca ccagcagctc ttgctgatct aggtgttcat tatgtgatca
    30421 tcggacattc agaacgtcgt gaatatttcc atgaaacaga cgaagacatc aataaaaaag
    30481 cgaaagctat ctttgcaaat ggtatgacac caatcctatg ctgcggcgaa tctttagaaa
    30541 cctatgaagc aggcaaaact gctgaatgga tcgaaggaca aattacagct ggtttagctg
    30601 atctttcagc tgaacaggtg tcaaacatgg ttattgctta tgaaccaatc tgggcaatcg
    30661 gtactggtaa atcagctgac gcacaaatcg ctgacgaaat ttgtggagtt gtacgtcaaa
    30721 cagttgaaaa actttatgga aaagaagtat cagaagcagt tcgtatccaa tacggcggtt
    30781 ctgtaaaacc agaaaatatt gctgaataca tggcaaaaga aaatgttgac ggtgctttag
    30841 tcggtggcgc aagcttgcaa gcagattcat tcttgtcatt gttagacgct gtaaaataat
    30901 tgttgaaaat ttgcgaaaaa tgcaagaaat gtttgcacta atgagcaaaa ttaactaaaa
    30961 tcgtatatga gggaaatccc ttaggaaaaa acaaactcaa aggagagaca aaacatgtca
    31021 attattactg atgtttacgc tcgcgagatc ttagactcac gtggtaaccc aacaatcgaa
    31081 gtagaagtat acacagaaag cggagctttt ggccgcggaa tggttccttc aggtgcttca
    31141 actggtgaat acgaagcagt tgaattacgt gacggagaca aagctcgtta tggcggtaaa
    31201 ggtgtaacta aagctgtcga caacgtaaac aacatcattg ctgaagcaat cattggctac
    31261 gatgttcgtg accaaatggc tatcgacaaa gctatgatcg ctttagacgg aactcctaac
    31321 aaaggtaaat taggtgcgaa cgctatttta ggtgtttcta tcgctgttgc acgtgcagct
    31381 gctgactacc tagaagtacc tttataccac tacctaggcg gattcaacac aaaagtattg
    31441 ccaacaccaa tgatgaacat catcaacggc ggatcacatg ctgataactc aatcgacttc
    31501 caagaattca tgatcatgcc tgttggcgct ccaacattca aagaagctct acgtatgggt
    31561 gctgaagtat tccacgcatt agcttcaatc ttgaaagctc gcggattagc aacttctgtt
    31621 ggtgacgaag gtggatttgc tccaaacctt ggttcaaacg aagaaggttt tgaagtaatc
    31681 atcgaagcaa tcgaaaaagc tggctatgta cctggtaaag acgttgttct tgctatggat
    31741 gctgcttctt cagaattcta cgacaaagaa aaaggtgttt acgtactagc tgactcaggc
    31801 gaaggcgaaa aaacaactga cgaaatgatc aaattctacg aagaattagt ttctaaatat
    31861 ccaatcatct caatcgaaga tggattagac gaaaacgact gggacggatt caagaaatta
    31921 actgacgtat taggcgacaa agttcaatta gttggtgacg acttgttcgt aacaaacact
    31981 caaaaattat ctgaaggtat cgaaaaagga attgctaact caatccttat caaagtgaac
    32041 caaatcggta cattaacaga aactttcgaa gctatcgaaa tggctaaaga agctggctac
    32101 acagcagttg tatctcaccg ttctggtgaa acagaagatt caacaatctc tgatatcgct
    32161 gttgcaacaa acgctggcca aatcaaaact ggttctctat cacgtactga ccgtattgct
    32221 aaatacaacc aattactacg tatcgaagac caacttggtg aagttgcaga atacaaaggt
    32281 ttgaaatctt tctacaactt aaaaaacaaa taattctttt ctaatgaaga tacatgatcg
    32341 actattgaaa gatagtcgag tatgatcact tagttaagta atcgaactct ctacttgctg
    32401 aaatatcagc aggtagagag tttttttgca actagcttct gtatatgatg tttacaaaga
    32461 atggtacaag aaaagatcat ccttgaaaaa ggaaagctaa caataactag catcatataa
    32521 gagcttttaa ggatagaaca gtagaatagg aatctatggg caagtcctct cgtataaata
    32581 aaataggagg gaagtagcag catatttttc ataaagtggc tctctttctt catttttact
    32641 ttggttgctc ctatttgaaa attcgagcac actcaaatac aataaaaaga aatggcaagg
    32701 gagaggatta gatgaaaaaa gaagaaaaaa tcgcgatttt acaagagatt atccgaatta
    32761 aatcagtgaa tggaaacgaa ggtgaagtag cagcctattt gaataagctt ttggcaaagc
    32821 atgacataac aggagagatt gtttcttaca gagatggtag agataatttg attgctcgtt
    32881 accaaaaggg ccaatcagga aaagtgttag gcctatctgg acatatggat gtcgtggcgg
    32941 ctggtgatga atcgtcttgg acctatgcac cctttgcagc agaaatccat gggaaccgtt
    33001 tgtacggacg tggtgctaca gatatgaaga gtggcttggc agcaatggtg attgccatga
    33061 tcgaactgaa agagtcagga aaaccattta acggaacagt caaattatta gccactgtcg
    33121 gagaagaagt gggtgaacta ggtggggaac agctcacgaa agcaggctat gtagatgact
    33181 tagatgcctt gatcatcgga gagccaacca attacagttt gatgtatacg cacatgggat
    33241 caatcaacta tacagtcacc tcgcacggaa aagaagcgca tagctctatg ccagaccaag
    33301 gttataatgc aatcaatcac ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc
    33361 acctcgctga aacaatcgag aatcctgtcc taggaaaaac aatccataat gttacattga
    33421 tcagtggcgg gaatcaagtc aacagcatcc caagccatgc gcagctccaa gggaacattc
    33481 gatcgattcc agaataccca aatgataaaa tcattgcatt gctgcaatca atcgtcaatg
    33541 aattgaatca agagacagac tatcatttgg aattgatgat cgattacaac aaaatacctg
    33601 tcaaagctga tccagattct cctttgattc attgcattca gcaacaattc agccagccat
    33661 tacctttagt tggagcggca gcaacaacgg atgcagccga atttacgaaa gctaaccatt
    33721 ccttcgactt tgtcgtcttt gggcctggtg tcgttacttt gcctcatcaa gtagatgagt
    33781 atgttgaaat cgataattat ttggatatga tcgaaaaata tcaaggaatt attttatcct
    33841 acttagcgta agattttttt aataaacgcc gtttgtataa ttaagcgaga caaataaaaa
    33901 agccatttat gttacactc
//
LOCUS       DAIGUC010000030        33705 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.030, whole genome shotgun sequence.
ACCESSION   DAIGUC010000030 DAIGUC010000000
VERSION     DAIGUC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.030"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            139..771
                     /locus_tag="NOB46_001536"
     CDS             139..771
                     /locus_tag="NOB46_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058473.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(905..1030)
                     /locus_tag="NOB46_001537"
     CDS             complement(905..1030)
                     /locus_tag="NOB46_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058474.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1164..2057)
                     /locus_tag="NOB46_001538"
     CDS             complement(1164..2057)
                     /locus_tag="NOB46_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HCI1058475.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2239..3165)
                     /locus_tag="NOB46_001539"
     CDS             complement(2239..3165)
                     /locus_tag="NOB46_001539"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HCI1058476.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3250..4011)
                     /gene="pflA"
                     /locus_tag="NOB46_001540"
     CDS             complement(3250..4011)
                     /gene="pflA"
                     /locus_tag="NOB46_001540"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCI1058477.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4255..6486)
                     /gene="pflB"
                     /locus_tag="NOB46_001541"
     CDS             complement(4255..6486)
                     /gene="pflB"
                     /locus_tag="NOB46_001541"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCI1058478.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6763..9213)
                     /gene="parC"
                     /locus_tag="NOB46_001542"
     CDS             complement(6763..9213)
                     /gene="parC"
                     /locus_tag="NOB46_001542"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCI1058479.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9225..11270)
                     /gene="parE"
                     /locus_tag="NOB46_001543"
     CDS             complement(9225..11270)
                     /gene="parE"
                     /locus_tag="NOB46_001543"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCI1058480.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11436..11870)
                     /locus_tag="NOB46_001544"
     CDS             complement(11436..11870)
                     /locus_tag="NOB46_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCI1058481.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11997..12635
                     /gene="plsY"
                     /locus_tag="NOB46_001545"
     CDS             11997..12635
                     /gene="plsY"
                     /locus_tag="NOB46_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCI1058482.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGLNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12767..13642)
                     /locus_tag="NOB46_001546"
     CDS             complement(12767..13642)
                     /locus_tag="NOB46_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI1058483.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13724..14515)
                     /gene="codY"
                     /locus_tag="NOB46_001547"
     CDS             complement(13724..14515)
                     /gene="codY"
                     /locus_tag="NOB46_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCI1058484.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14533..15933)
                     /gene="hslU"
                     /locus_tag="NOB46_001548"
     CDS             complement(14533..15933)
                     /gene="hslU"
                     /locus_tag="NOB46_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HCI1058485.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15947..16495)
                     /gene="hslV"
                     /locus_tag="NOB46_001549"
     CDS             complement(15947..16495)
                     /gene="hslV"
                     /locus_tag="NOB46_001549"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HCI1058486.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16532..17437)
                     /gene="xerC"
                     /locus_tag="NOB46_001550"
     CDS             complement(16532..17437)
                     /gene="xerC"
                     /locus_tag="NOB46_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCI1058487.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17635..19011)
                     /gene="trmFO"
                     /locus_tag="NOB46_001551"
     CDS             complement(17635..19011)
                     /gene="trmFO"
                     /locus_tag="NOB46_001551"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HCI1058488.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18980..21058)
                     /gene="topA"
                     /locus_tag="NOB46_001552"
     CDS             complement(18980..21058)
                     /gene="topA"
                     /locus_tag="NOB46_001552"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCI1058489.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21180..22037)
                     /gene="dprA"
                     /locus_tag="NOB46_001553"
     CDS             complement(21180..22037)
                     /gene="dprA"
                     /locus_tag="NOB46_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCI1058490.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(22093..22860)
                     /locus_tag="NOB46_001554"
     CDS             complement(22093..22860)
                     /locus_tag="NOB46_001554"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCI1058491.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22853..23713)
                     /gene="ylqF"
                     /locus_tag="NOB46_001555"
     CDS             complement(22853..23713)
                     /gene="ylqF"
                     /locus_tag="NOB46_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCI1058492.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23973..24371
                     /locus_tag="NOB46_001556"
     CDS             23973..24371
                     /locus_tag="NOB46_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI1058493.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24650..25150
                     /locus_tag="NOB46_001557"
     CDS             24650..25150
                     /locus_tag="NOB46_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI1058494.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25233..25784)
                     /gene="lepB"
                     /locus_tag="NOB46_001558"
     CDS             complement(25233..25784)
                     /gene="lepB"
                     /locus_tag="NOB46_001558"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI1058495.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25936..26163)
                     /locus_tag="NOB46_001559"
     CDS             complement(25936..26163)
                     /locus_tag="NOB46_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HCI1058496.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26160..26678)
                     /gene="msrA"
                     /locus_tag="NOB46_001560"
     CDS             complement(26160..26678)
                     /gene="msrA"
                     /locus_tag="NOB46_001560"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI1058497.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26698..27411)
                     /locus_tag="NOB46_001561"
     CDS             complement(26698..27411)
                     /locus_tag="NOB46_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HCI1058498.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27414..28310)
                     /locus_tag="NOB46_001562"
     CDS             complement(27414..28310)
                     /locus_tag="NOB46_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI1058499.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28468..29310)
                     /locus_tag="NOB46_001563"
     CDS             complement(28468..29310)
                     /locus_tag="NOB46_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1058500.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29442..30095
                     /locus_tag="NOB46_001564"
     CDS             29442..30095
                     /locus_tag="NOB46_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCI1058501.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30158..30685)
                     /locus_tag="NOB46_001565"
     CDS             complement(30158..30685)
                     /locus_tag="NOB46_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI1058502.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30705..31652)
                     /locus_tag="NOB46_001566"
     CDS             complement(30705..31652)
                     /locus_tag="NOB46_001566"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCI1058503.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31664..33550)
                     /locus_tag="NOB46_001567"
     CDS             complement(31664..33550)
                     /locus_tag="NOB46_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1058504.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
BASE COUNT         8883 a         7066 c         5807 g        11949 t
ORIGIN      
        1 gtaaaaacat tgtatagcat tttacacagg agtctggact tgactttttt atttattatt
       61 ttgattaaaa aacatcgaca tatactcatc aatttgttat tatactttat atacttatca
      121 atttaatttg gagatattat ggaaattcaa cgtagaacca ctaatttttt acatttaggc
      181 tctttttttg caactttgac gatcttattt tttctatgtt attcatacct taagacctca
      241 catgcgcctt ctagtgcatt aggctggttg cttttggatc attctgatat cacagaagcc
      301 gaagaaaatc cgtttttttt gattttgtct tctctttgcg gcttactgtt ttctgtttat
      361 ttcggtgcct atttttttca tcgacatcct ggtacgttaa acgaagcttc aagcgtattg
      421 attgcattta aaacgttttc ttttttagca attctttttt attcgtttaa tcacaatacg
      481 cttttcttct ttatcatgaa tggtttagtc gtgattttat ccatttttac ttattttatt
      541 ttttcactca tttttagcca attgaaatgt ccgctcttct ttcgattagt tcctgtcacc
      601 tgttttattt acagcttgtt ttcctttttt gtccttgctt taatgccact gaccaaccct
      661 tcgacgatcc aagtcgcagg aaatctgttg gatatgctct tcatcgtcag tctaggtgta
      721 tttatgtggc aaagaaaaaa caaacaaaat aaaaagcatt ttgaagcctg actattacga
      781 cttcataaat gcttttttag ttttaaacac ttcaatctaa aagaataacc caagattgga
      841 taaattatta atgactcgcc attcgtttct tagtgattct ggattatcaa atggacttcc
      901 taatctaatc agctagttct tcccataaaa tgccatactt gactgaatca taatattgat
      961 tatttaaaaa tctaactttt cttatcacta cttcctttgt cattccacat ttctcaccat
     1021 ttttttgcat tcctttgttt ccagaccatg tagtgaatct aataggtggt agataggcaa
     1081 aatactcaaa taattctttt aaccataaag gaagagaaag gctcctcctg caagagtcag
     1141 tataattttt gcttactgct ctcttaggtt ttactcacta aaactgttcc atattctttg
     1201 atataagaaa atgcatgcgg tataaatttc ttgctcagct cagaaaagat ttgtcgttta
     1261 agaaaggcca tttcctccat tgtcaatgaa ggatccaatg ttggtaattc aatctcaaaa
     1321 ttgttttttt cgacaatagg taattctaat gtgaatgatt cttcttcctt tatagtattc
     1381 gtcacaagta gagactgatg gaaaatacta ggccggcgat ttttatattt attcttacgt
     1441 atcctgtcaa cgataacttc tatttgatca aaaaagtacg attcatttac gtctccaata
     1501 agttcggcta attctttgaa tgccttcgtt acaggaagct gattcttctg tacaaaaaag
     1561 taattagcca aagtaagcgg gaagtgttct atagaggaaa gtgtgataaa acggtacttc
     1621 tcatttcctg cagttgtcct cagcaattct gtctctcggc tgtttcttac tccataaaaa
     1681 tacgcttctt tccgttcatc ttcgaaacaa tacgcccaaa taacttctcc catcgctaat
     1741 ttttgttcat caacagagag tctcttcaat tgttcagcta tggtttcagc agccgaagtg
     1801 gcttgttgca agtaatcttt aggatcaaat attggaaagt tcaaatgata tcttcgttct
     1861 tccctcttga ttaatcctgc atcgatcaat aaatcaagaa aatgggaaaa tttattttgc
     1921 gaaaattctt ttttcaattc tcttagaatc gtttcttgtt ctcgatgttc atatagataa
     1981 tcggtcaatg aagaaaaaag cggatcatcg gtcagttttt gataaaagtt ttccttattt
     2041 tttgaataat agttcatata tgttctcttt tctatccgtt ttattttact taaaaggctt
     2101 ttacgtaaaa aggaggaaga acaagagtca taattgactg ttattctcct ccatttcttc
     2161 ggcctttagt atgttctatg tttcttttta tatcaatcgc ttatccattc attttgaatg
     2221 cttcatacta ccatttgatt agctaaatac agccgtcaat tgaggtacga cttgtttttt
     2281 acgtgaaacg acacctttaa gcaaagcacg gttgttggtc aaagttgttt ggaaagcttc
     2341 ttctactttt tcttttcctt taccagcaac aagtaattct gaatcactgt ctaagatgtt
     2401 tgtgacaact aatacgaaca gatcgtagcc atttgctttc atttcatctt ccattgctgc
     2461 ttctagctct gcttgtcgat ccatcacttc attaaggtcc actgtattga cttgagcgat
     2521 acgaacgttg gaactgccca ttgggaaact ttttgcatcc aaatcaagaa gaaccgcagc
     2581 tgatttatca cttagatttg ttcctgcttt caacatttca agtccataag tgtttagatc
     2641 gacttcagcg attgctgcaa gttcttttgc agctgcttca tcttcaggcg tacatgttgg
     2701 tgatttgaac aacaatgtat ctgaaatgat agctgagagc atgattcctg cgatttcttt
     2761 aggaattgtt acttggtttt ctttatatag ttttaaaata atcgtacttg tacatccaac
     2821 tggttctgca cgatagtaca atggattagc tgtttcaaag tttgcaatac gatggtggtc
     2881 tactacagct aaaatattta cttcgctgat atctgaaata ctttgttgga attcattatg
     2941 atccacaagc atgacatctg cattttctgc tttagctgac tctactactc gtggtgcaga
     3001 tagctgaaag tggtctaatg cgtattgtgt ttcttcatta ggtgtaccta gagcaactgc
     3061 ttctgtttct ttacctaatt cattttgcaa gtgtgaaaac gcaatggctg ccccgattgc
     3121 atctgtatct ggattttggt gaccaaaaac taaaattttt gacatgtcat tcgctccttt
     3181 gtgatttctc ctatttaata atagcaaaaa aacggaaaga agcaatactt atcttctttc
     3241 cgatgcgacc tatcgcgtta aatattttgt atactcttct gtatgaagca atcgtttagc
     3301 attttcgaca cgttcttttg taggtggttc gatcccttct aatggatatt tcaaaccaag
     3361 tgtttcccac ttgtattttc ccatcgtatg ataaggaaga atctctactc tgtctacatt
     3421 tgacaaggtt tgaataaagt tgtctagtcg gatcaaatat tcatcataat cacttcgctc
     3481 aggaactagt acatggcgaa tccaaaccgg tttgttgatt tttgacaaat attgagccat
     3541 ttctaaaata ttttcattgt cccaatgcgt tagtttttta tgctcttcat tatcgatgtg
     3601 tttgatgtca aataacagta aatctgtata cttcatcaat tcttgaaaac gtgaaaagaa
     3661 aggttcttca tacgtaaaag gttttccgca tgtatccaat gtagtatgca tcttccgctc
     3721 ttttgctttt ttaaatagtt cgatcaaaaa atcgatctgc aatagaggtt ctccaccact
     3781 aacagtaata ccacctttat ctccccagta aggtctgaag cgttctgctt tatctaaaag
     3841 ttcatctgct gtgtattctt tccctccgcc aatattccaa gtatctggat tgtgacaaaa
     3901 ttggcaacgc atgcggcatc cttgcataaa cacgacaaag cgcagtccag gtccgtctac
     3961 tgaaccgaaa gtttcgatag aatgaacata gccgattgtt ttttcttcca tttaagttca
     4021 catcttttct ttgatttcat tttaagtaca agttagctgt cgaagcgaag ctttctgaac
     4081 aaaatttttc gcaattgccg cttcgttatg tgtaaaattt acagggacgg aacatacaag
     4141 tcctgcccct gtaaatcgtt tctttcaaat aagcatactg attattcgat tttgatgcga
     4201 tggctattca acgtcctttc gacgctaagt cgaaaaactt ttttcacgaa ctttttacat
     4261 tctgtcgtgt gaagttctca tcaagacatc taattgttgt tctcttgtca agtcacggaa
     4321 tttaactgca taaccagata cccggatcgt caagttcgga tatttcattg gattttccat
     4381 tgcatcacgc aataaatcat tactgaatac attgacattc aaatgataag ctccttttga
     4441 gaagtatcca tctaagacat tacgcaagtt ttcgattctt gtatcttgtt cttttccaag
     4501 acctgaagga ttgattgttt gggtatttga aattccatcc aatgcacagc cgtaattcat
     4561 tttagctgtt gagttcaggc tagctaataa cccactttgt tccgcattgt aacttggatt
     4621 tgctcctggc gcaagtggtt ttccagcttc acggccatca ggagtatttc ctgtattttt
     4681 accgtaaaca acatttgaag taatcgtcaa taatgaagtt gttggttttg agttgcggta
     4741 agttttatga cgtttgattt gtcccatgaa gtattccaag atccatgaaa ctaattcatc
     4801 tgcacggtca tcatcatttc cgtatttagg gaagtcgcca tccacttcaa aatcaactgc
     4861 tattcctttt tcattacgga ttgcttttac ttttgcatat ttgatcgctg acaagctgtc
     4921 tgccgcatga gagatcccag caatacctgt agcaaatgtg cgttgcaagt cagaatccat
     4981 caaagccagc tgagctgctt cataagaata tttatcatgc atataatgaa tgatgttcaa
     5041 cgtattgaca tatagttctg ctaaccaatc catcatattc atgaagttat gtttcacttc
     5101 ttcaaagtct agtatttctg atgtgattgg acgatattct ggtccaactt gggcgccagt
     5161 cacttcatcg actccgccat tgatggcata taatagtgtt ttagccaagt tagcacgagc
     5221 gccaaagaat tgcatgtctt ttccgacaac tgttcctgat acacagcaag caatcgcaca
     5281 atcatcagaa ccccattgtt cacgaagctg attatcattt tcgaattgaa tcgaagaact
     5341 ttcgatagcg attctgctag catatgttct gaatccttct ggaaggtgtt cagaatacaa
     5401 aacagtcaag tttggttctg gtgaaggtcc catatttgtt aatgtatgaa gcagacggaa
     5461 atcattcttt gtaactaatg aacgaccatc taatcccata cctgcaatgg ataaagtagc
     5521 ccagataggg aatcctgaga ataattggtt atattcaggt gtacgcgcga atttgaccat
     5581 acgtaatttc attactaagt ggtcgatcaa ttcttgtgct tctttttctg tgattactcc
     5641 attatccaaa tcacgttgga tatagatatc aaggaatgct gagatacgtc cgattgacat
     5701 cgcagcacca ttttgtgatt tgattgctgc taaatatccg aagtatagcc attggacagc
     5761 ttcttttgca tttgcagctg gtttagaaat atcatagcca tatttcgcag ccatttcttt
     5821 catttgcgct aatgcacgat attgttcagt gatttcttca cgtaaacgaa tcacttcttc
     5881 actcattgta tgataaccag tcatatcatg atcttttttc ttttgttcca tcaaatagtc
     5941 gattccatac aatgccacac gacgatagtc accgatgata cgtccgcgac cgtaagcgtc
     6001 tggaagccct gtaatgattt tgtttttacg agcagcacgc atttcagcag tataagcgtc
     6061 aaatacacct tgattatgtg ttttgcgcca gtcagtgaaa atatgtgtca attcatcgtt
     6121 tggtgtatag ccattgcttt ttagcgcatt gttagccata ttgattccgc cgaacggcat
     6181 gaatgcttgt ttcaaaggtt tgtctgtctg tagaccgacg attttttcca aatctttatc
     6241 caaatagcct gcatcgtgtg aagtaatagt tgatacgatt tctgtgtcca tatcatagac
     6301 accgttacgc tcgaattgga tatcatttaa cttttgcaat tcatcccata atttttctgt
     6361 tgcttctgtt gggccttcca aaaagctgtc atcaccgcga tattcagtgt agttattttg
     6421 aataaagtct ctagtgtcta cgccttcttt ccatttggta cctttaaatc cattccattg
     6481 ctccattgta tggacctcct aaatttctgt tttatgtaac agtttttacg tgattagtat
     6541 aacacagcac cctatctttg caagggtttt cttgtttttt atttaacaat ttttatgttt
     6601 tatttacata tatttaaatc aacgttgaca taccaacatt taagcattgt gaacactttc
     6661 atcttttttt gcaaacgtat aaggatttat taaaaatgaa tgaaaaagag acgccacctg
     6721 tattaataca gatggcgtct cttcattaaa atactacaac agttacgact cgatgaaaat
     6781 ctcaggagca tcgataactt cgatgacttc tccacctttt ttctcatcca tcgcaaatga
     6841 tccattcgat gttcgatcac ctatagggaa atcagttggg tcaatcgtta actgctgccc
     6901 tttttgattc atcaaggtta tttcttttga tcttccttcc gacatataga taatacggtg
     6961 cggatttttt ttcagctcac gcatgaccgt cactccccgc ttcgcacgtg aagtttggct
     7021 gatttcttga gcaagcatgc gtttaacagc tcctcgctga gtaacgatta cgatcggcgt
     7081 atcaccttct gctaacacaa gcagcccgtt gataatccta tctccatctt tcaaattcat
     7141 agacttcact ccagctgcct ttgctccaac aacgggaaca tctgttaaag gatagcgcaa
     7201 acccattcct tgatgcgtta ctaagaaaac atctaagcct ggctgatctt ctttcagata
     7261 cacagcaatc agttcatctt cttccgcctt tagcttcata cagctgagcg gacggctctt
     7321 ataggtgcgc catggttcga actctgtcat tcgtgtttgc ttgatcaatc cattcttgct
     7381 gatgaataca aatgttttct ctgcttgaat tttttgatat gggaaaacag ctaaaatcga
     7441 ttcgtctaca gacagattgg agattgtttg agaaatgtgc tcaccagcat ctttccattt
     7501 caaatcgggt agttcatgga cagggcggta gatcacattt gctttatttg tgatcagaag
     7561 aacatggtcc aatgtactca attcacctga gtatagcaag tagtcgcctt ctcgcatccc
     7621 gatttcttct ggtttggaag cactataaga acgaaggctt gttcgcttca catagccttc
     7681 tcgcgtcaca ctgacaatta cgtcttcttg tgccactaag acttgcgtat caattttgat
     7741 ttcttcgatt tcgtcttcga ttgtcgttag acgagcggaa gaataatttt ttttcacttc
     7801 tcgcaattct tttttcataa cagagaaaag ctctttgtca tttgaaagga ttttattcaa
     7861 ctctgtgatt tgcgcaatca agctttcgga ttccttttga agctctgtga tatccgtgtt
     7921 cgtcaaacgg tataattgca atgtgacaat tgcttctgct tgttcttctg taaattgaaa
     7981 gacgtcgact aaattctttt tggcgtcttt tttgtcttta ctttcacgaa tcgttgcgat
     8041 tacttcatcc agaatcgata aagctttcat caatccttct acgatatgct gtcttttttg
     8101 agctttggct aaatcgaatt gactacgttt tgttatgact tgctttcgat gctcgatata
     8161 acttcttaaa atgtctttca gtccaacttg atgcggagtc atatggtcga tagcgaccat
     8221 attgaaattg taattgatct gtagctcagt gtttttgaac aaataattca aaattccttg
     8281 agcattggcg tcttttttca attcgacgac aatttgcaga cctgttctat cactttcatc
     8341 tcgtacttca gctattccat cgattttctt attcaaacgg atctcatcca tttttttcac
     8401 caaggtcgct ttatttactt catatgggat ttctgtgatc acgatttgct gtttattacc
     8461 cttcattgcc tctatctttg ttttcgaacg aagaataact tttcctcgtc ctgtttcata
     8521 agcttttttg atttcatctt ttccttgcaa gatccctcct gttggaaagt caggtccagg
     8581 aatatattcc atcaattttt caaggctcgc ttgtggatga tcgatcatat agattgtgcc
     8641 atcgatcact tcagctaagt tatgagtcgg gatttctgtt gcatatccag cagatatacc
     8701 tgtcgatcca ttgacgagaa ggtttgggta tcgagctgga aggactgttg gttctttttc
     8761 tgtatcatca aaattccaca cgagatcgac tgtttctttc tcgatatctg ctagcatctc
     8821 tccacttaac ttggataatc tggcttcagt ataacgcatc gcagcaggtg gatcaccgtc
     8881 catactcccg ttattcccgt gcatttcgat cagtacttcc cgcaacttcc agtcttggct
     8941 catgcggacc atcgcttcat aaatactgat gtcaccatga ggatgataat tccccatgat
     9001 atttccgaca gattttgctg atttacggaa tcctttgtca tacgtattgc catctttgtt
     9061 catggcaaat aatatccggc gttgcactgg cttcaatcca tcacggatat caggcagtgc
     9121 acgttcttgg ataatatatt tggaataacg tccgaagcgg tcacccatca cttcttctaa
     9181 agttaattct tgtacttctt gtcgattttc catcaggtga cctcctattc tacttcaaat
     9241 aactgattgt tttcattttt atctgctcgt tcttcatcta ataaatcatt agaaactgaa
     9301 ggagagattt cagtatcctc ttttttatct aagatactgc catcttcttc gagcgtaaat
     9361 tgcacgtgat tttcgatcca ttttcttcga ggttctactt tgtcacccat cagtgtggtt
     9421 actcgacgtt cagcttgcgc agcatcatcg atacggacgc ggatcaacgt acgggaagtc
     9481 ggatccatcg ttgtttccca caattgttcc gcattcatct ctccaagtcc tttatatcgc
     9541 tgcagcatat atcctttgcc gactttttta atcattgctg ccaattcgtc atctgtccac
     9601 gcatattcaa tgacttgctt ctttccttgt cctttggata ctttatataa aggcggtaac
     9661 gcgatatata ctttcccagc ttcaatcagc ggtttcatat aacgataaaa gaaagtaagc
     9721 agtaatactt gaatatgggc gccgtctgta tccgcatcgg tcatgatgat tactttgtcg
     9781 taattacagt cttcgataga aaactcagga ccgactcctg caccaatcgt atagatcatc
     9841 gtattgattt cttcattttt caagatatct tgcattttag ctttttcggt attgatgact
     9901 tttcctcgta aaggtagaat tgcttggaac tttctgtctc ttccttgttt agcagatccg
     9961 ccagcagaat ccccttcgac taaatacaat tcatttttct tagggtttcg ggattgtgcg
    10021 ggtgtcaatt ttcctgaaag aagagattcg ccttttttac gcttcttccc atttcggctt
    10081 tcttctctgg ctttacgtgc tgcttctctc gcttctctgg ctttgattgc tttacggacc
    10141 aacatctggc tcatttcgct attttcctgc aaataaaagc ccatttgttc actgatgacg
    10201 ttatctacta cggtacgagc aactggcgta ccaagttttt cttttgtttg cccttcaaat
    10261 tgcagaagat tttcaggtac acggatagaa agtacagcag ctaacccttc tctgaaatca
    10321 ctaccttcca gattcttgtc ccgttctttc agcaaaccaa cttttctcgc atattcatta
    10381 taagatttcg tcatcgccgc tttcatacca gcttcatggg ttcccccatc ttttgtccga
    10441 acgttattga caaaagataa aacattttct gaataaccgt cattgtattg ataagcgacc
    10501 tctacttcga taccttcttt ttctcctgaa aaataaacaa ctggtgtcaa tgtatctttt
    10561 tcttcattca gataatcaac aaattctttg attccttctt cgtaatgaaa aatttccttg
    10621 actggttctt ctccacgaag atcagaaaga gagattttaa cgccttttag aagaaaggca
    10681 gattctctta accgttcggc taaaatttca tatgaaaatt tcgttgtact gaatattgta
    10741 tcatctggta aaaaatggac agtcgtcccg tttgcttttt ttgtttttcc tatctttttc
    10801 aaagtaccgt caggtttacc gccgttttta aatttctgct gatactctac gccatctcta
    10861 acgatcgtta caattagcca tttcgataag gcatttacca cactggctcc tacaccgtgc
    10921 agtccaccag aagttttgta ccctccttga ccaaactttc cgccagcatg cagcacagta
    10981 aaaatcactt caactgttgg tattccggaa gcatgcattc ctacaggcat cccacgtccg
    11041 ctatctgcaa cagttatact attgtcttca tggatggtca catcaatctc actgccataa
    11101 cctgataatg cttcgtcaac tgcattatcg acgatttcat agactaaatg atgcaagcct
    11161 cggctgtcag tggatccaat gtacatccct ggtctttttc taactgcctc taatccttcc
    11221 aatacttgga tggacgagtc attgtattcg ttgtttactt tttttgccaa ggcaaacgct
    11281 ccttcaataa tactttgcgg caaaaccgca ccacgattat catactagaa aaggtcgtga
    11341 aaaaaaagag ggtagacgag aaatcaattt taattatctc ctaaccgctt tttcgacatt
    11401 cccctctatc gatcatctct tctttgtggt catttttatt tttggttttc tttcaactta
    11461 ccaagttcaa tcttaataca acgatccatt acgatatctg tacgtcctgc ttttcttagc
    11521 atctcagctg cttctttgtt ttcaatccct aattgtgccc agaacacttt agcatcagtt
    11581 ttcaaaaaat cacctgctat ttcaggtaaa aattcactcc gtctaaatac atctacgata
    11641 tcgattggat catcgatttc tgtcaaattc gcatagactt tctcgcctag aatttcttca
    11701 ccagccaata atggatttac tggtatgatt ttatatccat tgtcttgcaa tacctgtgca
    11761 accatgtaac ttgttcgttc tggtttattg ctcaagccta cgacggcaat attttttgct
    11821 tcttccaaat agttgaaaat cgtttcttgt gttggatttt ttacagacat ttctgccacc
    11881 ccttgctttt ctttttattc catctattat acttgcatct ttcatttttt caattgttcc
    11941 tgttacctat tcatgctaaa ataaaggata gttttcaact tgaaagaggg taaaaaatga
    12001 aattgatctt attacttatt ttagcatatc ttttaggttc tattccttcc ggtgtctgga
    12061 ttggcaaatt gtttttcaaa aaagatatcc gacaacacgg gagcggtaat actggaacga
    12121 ccaatacatt tcgtgtatta ggcaaaacag ccgggattgt tgtcctgctt atggatattt
    12181 taaaaggtac attggctact tgtttgccga tgatcttcca cctttctggg attaaccctc
    12241 tttggtttgg ggtatgcgcc attcttggcc atacatttcc gatttttgct gggttcaaag
    12301 gaggaaaagc tgttgcgaca agtgcaggaa tgcttttagg acttaatcct gtattttttg
    12361 tttattcttg tatcatcttt atcgttagtt tattttgtac aagtatggtg agtttgagca
    12421 gtatgatcag tgcagtattg atcactttat ctacgatcgt ccttccttat gtagctcctg
    12481 tgattttggc taagcccaat tggttactga cgatcattgc ctttttagtt tcttccttta
    12541 tcttttatcg gcataaagac aatatcaagc gtatcagaaa ccatactgaa agtcgaatcc
    12601 cgtttggttt gaatagcagc aagaaaaaat cctgatactt tttcattcca aagagataaa
    12661 acgggagtgt gacaaatcga tgtcacactc ccttattact tacaggatag cttttttaca
    12721 caccttggta aacggtgttc cctgctaact tctcggtcac aacctcttac ttcactgtga
    12781 tggaatattt tgtcttgaag atttcatggg cacctagttg attgatccct actttttcca
    12841 tcaagtttcc actactgttc accgtgtcag cgattccgca ccacggttcg atacaaacga
    12901 aaggcgcttc ttttggataa ggagaccaga tccctacata aggcatatct ttatagctta
    12961 aagttacgct atgggaagat ttttcacttc gaatggcgta cgcatttaga ccccttgttt
    13021 caaaaaccaa ggcatcttgc tcaaaaagtt cacgattcaa agccagattc gtatttgtct
    13081 gacctaacgt cttttgatcc atatcgatga atgggccttt caatggtagg cgtaatcttg
    13141 atttcaatgg agaaaatgcc agatagaaat cttcaaatga caatccttct tcaagaggta
    13201 cattgaaagc aggatgtcca ccgatagaaa agaacatttc tttttcaccg gtatttgcca
    13261 cttgataatg aaccgtgatg ccgtctcctc ctaattcata gctgatcact aattcaaaat
    13321 caaatggata cttttctaat gtctccggcg tactccttaa gatgaaacta gccatttctt
    13381 gtccatgttc aatgacttca aaatccatat cccgagcaaa tccgtgttgc cccatttgat
    13441 atgttttccc ttgataaaca tactgatcat cttttaaacg tccaacaaaa gggaataaaa
    13501 ccggtgcatg tctgccccaa tacgctggat caccttgcca gatatactct aaaccatgtt
    13561 cttttgattt cagactgatc aattccgcac cgtgttcagc gatttcggcg atcagctggt
    13621 cattttgaat aataacagtc attgccattc ctccaacttc gacttacttt ttaaaatggg
    13681 aaggctggaa caaacatttc tatctgcccc agtcccctta cttctaataa ctgtgttttg
    13741 ctaactcgtc tttaaaacgg gaattcaata cttttaaata agttcccttc atgcctaacg
    13801 aacgagattc aatgattcca gctgattcca attttcgtaa agcattgacg atcacagaac
    13861 gagtgatgcc gatactatcg gcaatattag aagcagtcag acgaccttca tctccatcca
    13921 atgcttcaaa gatagcttgt acagccttca attcgctata agataatgtg ttgattgcca
    13981 tttggacagc cgttgcactc cgtacatctg cttcgatgct tcgagacttc tgataaagga
    14041 tctgcatacc gacaaccgta gctccatatt ctgctaagac tagatcgtca tctgcaaacg
    14101 attgttccat acgagataag ataatcgtac ccaaacgttc gccagctcca aagatcggaa
    14161 cgacagtcgt cagaccaaat ggatatttct ctcttgactc taccggaaat gcagtaatat
    14221 cactagtaat tgggatatta gcttcagttt tcatcaactg tgccactgta tcagtataag
    14281 attcaggaaa ttgtttctca acaaacattg ttttgattcg ttcattgttc acatcgtgac
    14341 gttcattata acctagtaat actccgtcac ttcctatgat ataggtgttg ctgtcaagaa
    14401 taccacctag tgtgacagcc attttatcgt aaggcaaatc tgcttgcatg tcaaaagtat
    14461 tcttttgctg caaaagtgtg tttatcttgc gggttttcgt tagcaagtct gtcattgtcg
    14521 tcctccgatt ttttataaaa tatagcgact taaatcttca tttgccgcaa ttgagccaag
    14581 tttgtcatcc acatatgctt ctgtgatcgt tatttctccc atttgcatat ctggtgcttc
    14641 aaataataga tcttctagta gtttttccaa aatggtatgc agtctgcgtg cgccgatatt
    14701 atctgtgtca cggttgacat cgaaagcgat ttgagcgatc cgttcaattg cttcttttgt
    14761 aaacgtaact gacacatttt ctgtaccgat caacgcgacg tattgtttta ctaaagcatt
    14821 atttggttcg gtcagaatct tcacaaaatc ttcagctgtc aaatcatcta attctacccg
    14881 tatcgggaag cgtccttgaa gttctggaat tagatcactt ggtttagaca aatggaaagc
    14941 tcctgaagca atgaatagga cgtgatctgt ttggatgatc ccgtattttg tgtttacttg
    15001 tgaaccttcg acaattggca atatgtctct ttggacgcct tctctggata cttctccaga
    15061 ttgctgtgat ttagaagtga tcttatcgat ttcatcgata aaaataattc cactttcttc
    15121 cgctaatttg attgcctcac tatggatatc agcatccttg actaattttg ctgattcttc
    15181 cttgatcaat aactctaaag cttctttgac tgttaccgtc cgttccactt ttttcttcgg
    15241 tgtcaaagca cctagagttt catttaggtc gatccccatt tgctccaatc cattgttcat
    15301 cattggtgca ggtttctttt ggtcttcaac ttcaatggtt acttcacgac tatccagtaa
    15361 acccttttgt agttgttcca agactgtacg gcgattgatt cgaatatctt ctgtcacttc
    15421 ttcttgcggt tcagcggtat tttgctgact agcattaaaa agattcatca tttgttcaaa
    15481 ttgattagtg gattgtttct gttctttttt gataccaggt accaagattt ttaccaaacg
    15541 tttttctgca ttttttttag cacttgtgta tacacggctg tactgctctt tttctacgat
    15601 ttggatcgca ttttctacta aatcccgaac cattgattct acatctcttc cgacataacc
    15661 gacttcagta aattttgttg cttcgacttt gacaaatggt gcattgacga tttttgccaa
    15721 acgtcgtgcg atttctgttt taccgacccc tgtaggtccg atcatcagca tattttttgg
    15781 tgtaatatct tgttgcattt tttcatctaa ctgcaaacgg cgatagcggt tacgcaaagc
    15841 aacggcaaca gatttttttg ctgcgtgctg tcctacgata tattcatcta attcacttac
    15901 gatttgtctt ggtgtttgtt ttaattcata catatctact cacctcttac agttcttcta
    15961 cgataatatt atgattagta aagatacaga tatctgcggc aatatttaac gcattttctg
    16021 caatttcttt cgcactcatg tcgttttgag catagttttt cattgctcgg gctgcagcca
    16081 acgcaaaatt ccctcctgat ccgatagcta agataccatc atctggtgtg ataacttctc
    16141 ctgtacctga aacaagaagc atttctttat cattcattac gatcagcatc gcttcaagtt
    16201 tttgcataga ttgctgtgtc cgccattctt gagctaattc gacagctgcg cgttgtagat
    16261 tcccgttata ttcgtttagt ttgccttcaa atttttcttc taaagtaaac gcatctgcaa
    16321 cacttccggc gaaacctaca acaacttctc cattgtagat acgtcgtact ttctttgcag
    16381 tgcctttcat gacaacagat tcacccattg ttacttggcc atctccagcc atagcaaatt
    16441 tcccgtcttt ttcgacggca cagatagtgg ttgaatgaaa tggtgattcg accatgtttg
    16501 tttcctccta aatttgttct tttccttatt tttacgctct tggatggaaa gaacgatagt
    16561 ttttttgtaa actttctttt gttacatggg catagatctg ggtagtcgat aaattggcat
    16621 gtcctagcaa ttcttggact gtccgcaaat ctgccccatt atttaataaa tgagtagcaa
    16681 atgtatggcg cagcatgtga ggatggatat cactatccaa actgcttttt ttgatcattt
    16741 gattcaagac atattcaatt ccagtaggcg tgattggttt tccatgatga ttcacaaaaa
    16801 cgatatcatg ctcttcgtga tattttgtca tcaatacctg gcggccttcc ctgaaatatt
    16861 cttgcagagc atcttgagca aaagaaccta gaggagcata tctctctttg ttccctttac
    16921 catggatcaa catgacctct gaatcaaaat caatgtctga taccgacaaa ctgctacact
    16981 cacttaaacg gatgcctgac ccgtaaagga cttccagtaa agcgcggttc ctcaaatcca
    17041 aaggactatc tcctgctacg ctgtcaaaaa gtgcttgcat ttcattttca taaaaaaaac
    17101 gtggcagtct caaatttttc tttttgagat gaacgtaaga aaatggattt tcttttatca
    17161 cttcttcttt gagaagatac tgataaaacg aacgtaggct ggctatcttg cgactgatag
    17221 aatttctgct atagctagga cgatgatcag ctaatgcact caaatagaca cgaaccgtaa
    17281 aatattccgc cttcagcaga tcagcgtctc cagattcctc caaaaaatgt ttgaaatgga
    17341 gaatgtcttc ttcatatgct tctttcgttt tttctgaata tcctctttcg acaatcaaat
    17401 aacgcaaaaa tttttgttcc cacgtggctt ctgtcatttt ctcaccttcc ttttgtccca
    17461 gagaataatt tagcacagcg tttataaaaa gacaaataaa ttgtcagaat ttaaccaata
    17521 tttctaagtt tgttcacaat tggcgcaatt cctcacattt tgtttgagaa attcttaaga
    17581 aaaacgcaag aaaaagagcg agactatccg tctcaccctc ttcatggagt ttccttactc
    17641 atttgggatt gcagtttttt ctaattctgt ttttattgcc tcattagctt ttaaagctcg
    17701 ttgtgcaatt gcttcatatc ttgctttttt gtctcgaatg cgctctggca gttcaggaaa
    17761 cagaccatag ttggcattca tcggttggaa atgttttcct tccgcatgag taatgtagta
    17821 agccatactt ccaatagctg tttcttgtgg aaactcgact ggttccattt cttttgctaa
    17881 gcgtgcggcg ttgattccag caagtagtcc gctcgctgca ctttcaacat agccttctac
    17941 accagtcatc tgacctgcaa agaacagatc ttcgcgtttc gttgattggt aagtcggttt
    18001 cagcaattct ggcgaattca taaagctgtt tcggtgcatc acaccatagc gaacgaattc
    18061 agcattttct aacccaggaa tcatccggaa aacacgtttt tgctcgcccc atttcaagtg
    18121 agtctgaaag cccacgatgt tgtataaaga agctgcagca ttgtcttgac gcagctggat
    18181 aacagcataa ggacgtttgc cagttttagg atcttccaat ccaactggtt tcataggtcc
    18241 gaaaagcatc gttttgaatc ctcgctgtgc cattacttca attggcatac atccttcaaa
    18301 atatttttct ttctcaaaag atttaagttc tgccacttcg gcattgatta gtgcctcatg
    18361 gaaagctttg aattcctctt ctgtcatcgg acagttcaag taagctgctt ctcctttgtc
    18421 atagcgggac ttcaaatata ctttatccat atcgatcgta gctttgtcta cgattggtgc
    18481 agctgcatca tagaaataaa aaccatctga accattgaat gctttgatgc tttctgctaa
    18541 tggatgagaa gtcaaaggtc ctgttgctac tacggtgatt ccttccggta tttcagtaat
    18601 ttcttcgttt atcactgtta ctaatggatg ctctttgact tttcgggtaa ttgtttcaga
    18661 aaaagaatcg cggtcaacag ctaaggcacc accagctggc actgctgttt catctgccga
    18721 agtgattact accgaattca atcggcgcat ttcttctttc aataacccta ctgcattagc
    18781 caaactgttt cctcttaatg aattggaaca tactagttca gcaaaattac ttgtgtgatg
    18841 cgcctcagtc gatttgactg gacgcatttc atataaacgg acagggactc ctgcttgtgc
    18901 gatctgccaa gcagcttcac ttccggcaag ccctgctcca acaacattta ccattttcaa
    18961 tgaaagaacc tcttttctat tatttttgga tgtcttcttc gtaatctcca tttacacaga
    19021 ctacttgttt accgcctttg actttcttct cgaccagata tccgtcacat tttggacaat
    19081 ttctgcccac tggtttatcc caagaagtga attcacattc tgggaaacgg gaacaaccat
    19141 agaatagtct gtttttctta gattttcgtt caatgacttg tccttcatga catactgggc
    19201 aagtcacacc gatttctttt acgattggtt tcgtattccg acaatcagga aaattactgc
    19261 aagcataaaa cttcccatat ttccctaatt ttatcaccat cggatgtcca cagacatcac
    19321 aatcgaatcc tgctggttca tctttgattt gaattttttc gattttttct tccgcattcg
    19381 tcagttcttt ttcaaacggt ttatagaaac gatcaaccac tttgacccac gcttccgtgc
    19441 cttcttcaat tttatccaaa tctccttcca tttctgctgt gaaatggata tcgacgattt
    19501 gagggaagaa ttcacagatt aatgaattga caatttctcc tagttcagtc ggctcaaatc
    19561 ttttttgtgt caattttaca tagtagcgtc tttggatcgt atcaagtgtt ggtgcataag
    19621 tggaaggtcg ccctaccccg ttttcttcta gtgcacgaat caacgtagcc tcactaaaac
    19681 gtgctggtgg ttgagtaaaa tgttgttttg gttcaatatc aacagattgg actacatcgc
    19741 cttcttcaag ttctggaaga atattttctt tctcttcttt gccgtcatct ctaccttcca
    19801 catacacttg catgaatcct ttgaatttga tttttgaacc gttcgcaatg aagatgacac
    19861 cattttgttc taatgtcact ttcattgtat ctaaaatagc tggtgtcatc tgactagcca
    19921 caaaacgtga ccagatcaat gtataaagtt tcaattgatc tttatctaaa tattgtttga
    19981 gttcatctgg tgtacgaagc acactcgttg gacgcacagc ttcatgggca tcttgtgcgc
    20041 cttgagcatt tttgatcttt cggtgatcat gtctagaaaa ttcttttcca tacgtatctt
    20101 caataaatgc tgcggcctct gcttttgctg tatcggcaat ccgggtagaa tcagtacgca
    20161 tgtatgtaat caagccgact gttccttgtt tacccaaagt gattccttca tataattgct
    20221 gtgctaccat catggttttt cttgttcgaa agtttaactt acgggcagct tcttgttgca
    20281 ggctacttgt agtgaaagga ttcgcagggt ttcttttgcg ctctttcttt tctacttttt
    20341 taacttcgaa gtctgttcca tcaattctag cagtgacttc ttttacactt tgtgcatctg
    20401 gtaatttctt tttcttaccg tcgattcccc agaaatttgc tttgaatttc ttgcgagctt
    20461 ttttaaaatt accgtcgatg ctccaatatt cttctggaac aaattctcgg atctcttttt
    20521 cacggtcaat aataattttt aaagcgacag attggacacg tcctgcactt aaccctttct
    20581 tgaccttacg ccagagaata ggactgatcg aataaccaac gattctgtct aaggtacgac
    20641 gagcttgctg tgcatctact aaatctacat cgatcgttct tggttcctta aaagctgctt
    20701 tgactgcgtc ttttgtgatt tcattgaaga ccacccgatt tttttctttc agatccaacc
    20761 caagtaggta cgctaaatgc caagcaatcg cttctccttc tctatccggg tcacttgcca
    20821 agtaaacttt ttgagctttt tttgctgcgg ctttcaggct tttgatgaca tcgccttttc
    20881 cgcgtataga aatataatgg ggttcataat tgttttcaaa atcgataccc attttacttt
    20941 tcggtaaatc tcttatatgg ccaacactgg ccattacttt atagtttcgt ccaagatatt
    21001 tctcaattgt cttggctttt gcaggtgatt ctacaatcac taaatattta tacgccatta
    21061 ctgaatggac tcctttccat tgtcgtgttc ctactattaa aagaggattc atacaaatcg
    21121 tagctaatca tatccattca gaaaacgttt gtcaagaaaa gcaaatgaaa agtatggtgt
    21181 tattctttaa attctgccaa gatatcttca cccgaaaccg tgcaaactgc accgtcttgg
    21241 atcaaatgat gacatccggt agaatgttct gttaaaatat ttcctggaac agaaaaaact
    21301 gttcttccaa gatccaatgc ttgctgtgct gttatcagag agccgctttt tttcttggct
    21361 tcaaagacac atgttccttt agacaaagct gcgataatcc gatttctcat tggaaaacaa
    21421 tgctttttcg ggccggattg aggaggatat tcactcaaaa gaagatgatc atttgcaatc
    21481 acctcttgca agtcacgatt ttcagcagga tagacttgct ctatccctgt tccaatgact
    21541 gcgattgtcc gtccaccatg agagattgct gcttggtgac cgtatgtatc tatccctttc
    21601 gcgcagccac tgacgatcac atatccagct tctatcactg gttttagtaa ataataaact
    21661 gtttttttgg ctaaagcaga agtgtgtctt ccaccaacaa cgcttaacat gttacaagaa
    21721 agtaaagata gatcaccatt ataaaacagt acaattggcg gataggtcaa gtgaagcagc
    21781 tgagggggat atttgggatc aaagcaagtg ataaacgact gtttcgattg gattttgccc
    21841 cagttagcgt gaatttcctg ccaacttttg cgaaacagct cccggtgttt ggttatttta
    21901 cctatcttaa tgatgtcttc aaatccgatt tctttataag gatactgcat catccagtta
    21961 gcaagtgccc attttccttg actactgatt ccttttgtat aagcaagttt caataaattt
    22021 tcttctattt gatacatcat aaaaccgcct ttcgtctctc tttctaataa gatacgtaaa
    22081 agcggctgtt ttttattgta aatatttttt tacaggtgca aaacttttac gatggattgg
    22141 cgtaattcct tgtcgttcaa gtccttctaa gtgttccttt gttccataac ctgcattatg
    22201 cgagaaacca tatccaggat aaagcacgtc atattctttc atcaattggt ctcgatatac
    22261 tttagcaatg atacttgcag cagcaatcga cacagatcgt gcatcccctt tgattatttt
    22321 ttcctgctga ataggcaaat ccaaggtcat cgcatcgatc aacaaatagc ttggtacaat
    22381 ggacaatttt tctactgctt ggatcatcgc taatttactt gcttcataaa tattcacatc
    22441 atcgattgtc tgctgatcaa cgatcccgat cccgattgcc agggcttttt cttgaacttg
    22501 ttgataaaga agttctcgct ttttctctga taattgtttg gagtcattca gccctaatat
    22561 gatctcattt ttcggcaaga taactgcagc tgccacgaca ggtccagcta atggtcctct
    22621 tcctacttca tcaatgccgg caatccattg gtgaccttgt gcgtaccctt gcttttcaaa
    22681 gcaaaacatt tcttcatatt tttccttaat taatgcttcc tttttcaatc gtcgttcaaa
    22741 agaagccagt gcttgctgca cgcctttgcg tggatcattt cttaatgatt ctagtgtagg
    22801 atcatctatt ctctgtatgc ttttcaatcg ttctttgata ctttggatgg attcagtcat
    22861 cacttttttg ctccatttct tcgcaacgat ccagtgtgta tcgtccaagt tttccttgac
    22921 gaatatcatg cacgactaat tcgctgccac gatcatagtc ttctttatac ccacgttttg
    22981 ctgtaatatc catcagtaat tccggtgcca atttttcttc ttgctcgatt gataaaccat
    23041 aacgatcgct gattcttcct gaataatatc gggcaaaaaa gtctaatccg taaatcgcta
    23101 aatcatctaa atggacaagc tggtctttga tcgcgcctgt cagcgctagt tttttgccga
    23161 tttcttcatc ttcaaatttg ggccataaaa tccctggtgt gtctaacaat tccaactcat
    23221 tacctaaacg aagccactgc tgaccttttg ttacgccagg cttatttcct gtctgtgcaa
    23281 ttttcttgcc tactagtcga ttcatcaacg tagatttccc aacatttgga atacctaaga
    23341 ccattgcccg aatagcgcga ggcttgatcc cccgagcagc atctcttgcc cgtttttctt
    23401 tcaatgcttc tttagccgca ggtactagac ctttaattcc tttactttct tgtgccgtga
    23461 tagctaatgc aagatggcct tgtttacgaa aatattcttg ccacagcttt gtctgttgtg
    23521 gatctgccag atccgcttta ttcaataaaa caaggcgagg tttttgctga atgatctgat
    23581 ctagcattgg attacgagaa gataaaggta atcgtgcgtc taccaattca aatacgatgt
    23641 ccacatattt cattttttca gaaacttctc gtcgggcttt tgccatatgt cccggaaacc
    23701 attggatggt cattgttctc tccattcctt tcataccgga atattccccg gctttacttg
    23761 tttttttctt tttcaatata aattcacttt tttattataa agaaattcca tctattagtt
    23821 aagtgaaagt gaaccagtcc tcattctatc acatcttcac ttttttgatg atgcaaattt
    23881 ttattttggt ttctatatat gaatctaaat ttttgacagc gtttcctaaa taagagatga
    23941 tagacgaaca aaacagaaag gagacgaaac aaatgaatag tatggttttt gttaattttc
    24001 ctgttgctga tgtcaatcgt tccgttgctt tttatgaaaa gctgggtttt aaaaaaaatg
    24061 aagaattttc tactgaagaa gctggttcaa tggtatggga tgacactttt tggataatgc
    24121 ttctctctca tgatttttat aaaaaattta taaaagataa agaaatagct gataataaaa
    24181 aaacaagtgg tgctttgatt tcgtttagtg ttgaaaatgc ggatgaagta aaaaaatttg
    24241 ctcaaattgc aaaagaaaat ggtggtactt tccacgaagt agatatggga atgcctgaag
    24301 aagaaatgtt ttcattagaa gtccaagatc tagacggaaa tacattagaa cccgtatgga
    24361 tgaagatgta agcagataac taatctgacg ttttttataa caaaaaaaca aaggcggatg
    24421 atacgataag tattctccgc ctctattttt tttattcgta caatctcttt tttacagttt
    24481 ataaaagcag tcttctcacc ctttttttaa ttgttagatg ccagtgtatg taaatcacca
    24541 atgtgtcatg acacattggt gattttatgg tatcctttta ttattaactg acaaaggaga
    24601 gaatattttg aacactttga ttgcaaaaga cgtttttaga ttgcccgaaa tgaatgcaag
    24661 attgttgtcg acctctgctc ttttattagc ccttgatgtc atcttataca agatagcgat
    24721 tggtcctgct tattttcaaa tcacattcgg atttttaagt atggcgctta tgggttatct
    24781 atatggaccg atctgggctg gtttgcttga aatgttgtcg aacactttaa atttcacgat
    24841 atttggttca ggaacgtttc aagctgcttt tcttatcacg gctttccttg gtggatttat
    24901 taatggctta tttttatatc ataaaaagat aaacctgcct tccgtcatcg ctgcccaatt
    24961 attgattatg atcccagtca gcctttttat caattcttgg ctgatgtctg ttttgtttgg
    25021 tgcagatttc aaagtaattt ttctaggtag attcatcagg aatatgatcc aaatccctat
    25081 tcaaataatg gttgtttatt catttatcaa aactttagag gctagaaaag tgtttaaacg
    25141 agctgtttga ttttacgtac taaggtagta aactgatttt ggattaaaca ataaagcgtg
    25201 cagtctcaac agactgcacg ctttattgtt tctcactgga tccattttat ttcatcaagt
    25261 ggataataga caaatcttgc tttacctaga atatcagttt tattgatcgt gccaaacgaa
    25321 cgactatctt ttgaaactct tcgattatct ccaagtacaa aataattatc ttccggaagc
    25381 ttggattgtc ccgttagctc ttgtagtgta aagtccgtcg tataggatgc atttgcatga
    25441 tctgatttca ggtttttagt tagataaggt tccttaacta ctttcccatt gatcttcaat
    25501 tgatcatttt ggtagctgac attttctcct ggaagaccga ttactcgttt gatataaatc
    25561 gtgccatctg ctaattgaaa aacaacaata tcaaatcgtc tgatctccga aaatttttcc
    25621 atcacaacca tatcaccttg cttcaacacg ttttccattg aattgccttc cactggtacc
    25681 gggatgaata aaaatccccg caacatgaac gcaaggaata cagaaacaag taagtatttg
    25741 aatacaagcc agaagcgatt aatatagcgt tgtttttttg tcaatctcta tcaatccatc
    25801 cctctttttt tcattctttc tttattataa gaaaaatatc aaaaaaatgc gactagatag
    25861 ctgaaataaa aataattctt tcaattaggc tattggacaa aaaacttttt tgatcataaa
    25921 gtacaaaact atctcttata tgtcatgatt attttctaaa tatttttccc atgcttcgtc
    25981 aaagatatcc atggacggca aatagtcgac attcagttcc agataattag aaatttcttc
    26041 gtagctagag ctgtgcttag gaaattggat gtctttaccg gcttctgtag cgaaaacaga
    26101 taaagcatca tgtgtgccac cgcctcgcag tgtcattaaa taatgaaaaa agcttcgatt
    26161 cacccttcgt tcctccaatt ttcttcgata aaggcagccc ggcgtgcatg gtttctttta
    26221 aaattttcag gatgcttttt ataatactct tgatggtctt cttctgctag ataaaatggt
    26281 tgggctggtt cgatttttgt aacgattggc tgttcgaaac gtccactttc agctaactgt
    26341 ttcttacttt tttcagcaat gatccgctgt tcttctgtca aataaaagat caccgggcga
    26401 taattgtcac cgcgatcctc gaattgtccg aaagcgtcag ttggatcagt ttgctgccag
    26461 taaagttcta ctaattgttc atatgaaatc aatgttggat catagataat ctccactgct
    26521 tctgtatgtc cagtcgtttg gctttttact tgttcataag tcggatctgg tacatgccct
    26581 ccagtatatc ctgacatcac tgtatggata ccaggaagcg tgtcgaaagg ctggatcata
    26641 caccagaagc agcctcctgc aaatattgct cgttccatta tgattccccc tctaatacta
    26701 ctcatccgat gattttttat tttcttttgt cttgctttca gtactgctgg tgctagtttt
    26761 gttggtattt gagttgtttg aagcatcaga ggtatctttt ggcaaatata gactaaaccg
    26821 aatgtcatca tttactaagt cgattttatc tgctttaata tacatcccgt tttgcattcg
    26881 gaattgatcc aacctaagca tgatagtcag atcatctgta ttgacttcga tccaatctgg
    26941 taatttatag tttctcttga tcatattcat cacatctttg attggcaaac tcaatgttcc
    27001 gatagaaaga cttctagctt ttagttggac atttccgttt tccatcacat acggatcaaa
    27061 atataaatag aaatcgatag gaaaacctag tacttcgaaa gtaccattga gtagtgcttc
    27121 attttccaaa taaaatttat attcaatatc actatctttt tgatactcac taaggaaaaa
    27181 gctgatgatt tgattgactt tttctttatt tgaattgatc gttaagacag gatctccttg
    27241 tctttccgta agagctggta tttctgggag ttctggttcc cgattagcaa aaatacggct
    27301 gcctaaaaat acggtcgaac caagtactac cccaagaagg ataaggaagg cgaatttcca
    27361 gtaatttgtt ttctttgttt tgtttgaaga tacgtcagat cttgttttca tgtttattga
    27421 tcatcctcct tctctaacca ttggttttgt gtctcgatca gctgatctct cactgcattt
    27481 gccatcaatt gataacctaa attatttgga tggaaatgat cttcttcata gagcacatta
    27541 tttttgatgc catttagatt ttctgtcgtg ctagttgttt gatctgttcc ttcttctgtg
    27601 acacctactt cctgattcaa tccttgataa agcaaatcat tgattgggat aaagtagcag
    27661 ttcggcattt tttttgtcac cgtttctgtt cctttgttcc aattgttaac aattgtctgc
    27721 atgtcagtga tctcaggaaa gttcaaataa aatggattgt agatgcctaa aatgtaaata
    27781 ggtgcggttt tattgaggga tcgaaattct tccaatagtt ctgtgacatt ttcctgatag
    27841 tttttcagtg gctttttaaa ggaattgacc gttaacccga ataaattatt ttggataact
    27901 ttcatcaaat cattaccgcc aacagtcagt gtgataaaat cagctgtttt gatattgttt
    27961 cgaatttctt cttttgtttt tactcgcttt aagatctggt cacttcgttc accatttaca
    28021 ccatagtttt ctgtttcaac cgcggtcaaa ttataacggt cttttagatc atttgcgaca
    28081 aggggaacga atcctccttg cttggtttga tctcctactc cttcagtcag cgaatctccg
    28141 atagctatgt agtgaagttt ttctttttta tttggatctt ctctcacagt agttactggt
    28201 ttcattagtg ggccagcttt cggtatagaa gcagctaaac ctgcatagat gatgatcgca
    28261 attaataatg ggaacaaaac gaggatcaaa tgtcgtttcg ttaatttcat tttttcacct
    28321 cttgtattcg attggttcta atgttatcaa aaattttatc aaaaaggtag tctttatgaa
    28381 aaaagaaaac aattattttc ctaattttat aaagaaaaag agaataagct gcaagccttt
    28441 caggctgagg gcttatcctc ttttcgacta atctacataa tacatgattg caaacgcgtc
    28501 tttaccagta tgcgtagcga taaccggatt cgtatgcagt acagggatat gcatgtccgg
    28561 gaataattct tgcaaaccct ctttgaattc ttgcgccaat tcttttgcat ccgcatgtga
    28621 aataccgatt tgtcgcacat ttggcaattc tttcagttca tttttcaaat tattaaacca
    28681 tttatcgaac gttttctttc ctcgcccctt agttacaggg attaattcag aatgggcgaa
    28741 attcatcacc acgcgtatgt tcaaaacact agacagcaaa ccagttgttc ggctgattct
    28801 tccacctttt accaagttat ctagtgtgga tattccgatg tataattttg tattgtcttg
    28861 tacttttttg acttcttcaa ggattttctc tactgtttta ccttcttttg ctaattcagc
    28921 tgctcgaatt acctgaaaag ataatccttg gtcagtggta tcactgtcga taaccgttac
    28981 tttcgttttt gttagattac tggcttgtct tgctgcttct actgttccac tcaagccttt
    29041 tgtcatatgg atcgaaatca cttcactgcc gtcttctcct agctcatcat acatcgagat
    29101 gaattctcca attggtggtt ggcttgtttt gggcagattt tttgctttcg ccatcatttc
    29161 cataaatctt tcgccgtcta gttggtcatc atcgggatat actgttccgt cgatcatgat
    29221 ggatagcggc atgacacgaa tgcctaaagc atcgcgtaca tttttttcca tcgtacatga
    29281 agaatctgtt acgattttta catttgtcat tattttctct ctctctttct ttaacaagat
    29341 gccttattca tgttaaacta catgtaagac aatttctatt tttagtataa cagacaaata
    29401 atgatttttc attaattaca cctagtaaag gagccgtttt catggaaaaa acgaaattta
    29461 atcgaacgta tgaaatatta aatgaagtgt ttaatgcagt cacccatgga attgggactg
    29521 gattgagtat cgcgggacta gtggttcttt tagtaaaagg tgcccacttg cattcctccc
    29581 tccatattgt ctcttatgct atctatggat cgatgatgat tcttttattt ttaacgtcta
    29641 ctttgtttca ttcattgatt tttacaaaag caaaaaaggt gttccaagta ttcgatcata
    29701 gttcgatttt tcttttgatt gcaggaagtt atactccttt ttgtttgctg agtatccgag
    29761 gatggctagg ttggacttta tttgtattaa tctggttgtt tgcgattctt ggcattatat
    29821 ataaagcgtt gacgttgcat aaacgggaga gagtatcaaa agtatctacg atcatctata
    29881 tttttatggg gtggctctgt gtcgtggctg ctgttcctct ttatcactct cttggaatga
    29941 ctggtgttat tttgatggta gcaggcgggc tttcttacac gataggcgca ttcttttata
    30001 gcttgaattc tatccgctat atgcatgttg tttggcattt gtttgttatg ttaggtgcag
    30061 gttttatgta cttctctgtt ttattcttta cttaataaaa aaaataaagc tatggatggg
    30121 acagctctaa ataacagcta gtctatccat agctttttta tatcgtcaat tcgcctgtcc
    30181 cgctttttac aggattctca ttacgctgat acgtttcaaa ttgatgcgga taacgatttt
    30241 tttcatccat ttctccttga ctagtattga tcagtgacca atcagaccag tcaacaggtg
    30301 gaaaataagc atctccatcg aatacatgat ggatgactgt acggtataat atcgtacaaa
    30361 atggcagaaa ttcttgataa acagctgacc ctccagcgat gaaaaagata ccgtctgttt
    30421 ctttttccag agcaagcacg tcttccacac tatgcatgac atgcacgcct tctgctttat
    30481 aggaagaatc tctcgtcaaa acaatcgtct gacgattcgg caacggacgg ctacccatcc
    30541 cttcgaatgt ttttcgtccc atcactagtg tatttgcttc tgtcatttgt ttgaagaatt
    30601 tcagatcatt tggcaaacgc caaggaagac ggtcttcttt tccaatcaat ccgttttcat
    30661 cctgtgccca aattgcagct aacattttct catcctttct gattctaaac agcgatagga
    30721 gctttgatcg ccggatgtgg gtcatatcct tctaattgga tatcttccat ctcaaaatca
    30781 aatactgact gcttttcctg attcaaaact aaagtcggaa atgcgcgtat ttctcggctc
    30841 aattgttctt tcatttgttc gatatgattg atataaagat gagcatctcc taatgtgtga
    30901 acaaattcgc caaccgctaa acctgtttca tgtgcaatta ggtgagtcag caacgcataa
    30961 cttgcaatgt tgaacggaac gcctagaaac acatccccac tgcgttgata caattggcag
    31021 cttagccgtc cctcttgaac ataaaattga aacatcgtat gacaaggagg caaagccatg
    31081 ctaggaacat cttccggatt ccatgcagaa acgatcaatc ttctagaatc aggagtcttt
    31141 ttgattgctt cgatcacttg tttgatttga tcgataaagc caccgtcttt tgtttcccag
    31201 tgacgccatt gatagccgta gatgtgtcca agatcgccgt atgtttcagc aaaggaatca
    31261 tcggttagga tcttctcgca aaaaagcttg ctctgctttt tatattcttc attgaattca
    31321 ggatctgtca aacatctatg gccaaaatca gtcatatctg gtccattata gtctggactt
    31381 ttgatgtagc gttcaaatgc ccattcatcc caaatatggt ttttattttg taatagatag
    31441 cggatattcg tatctccttt taaaaaccaa agcaattcgc ttttgatcaa tccaaaaggt
    31501 actcgtttcg ttgttaacaa aggaaaccct ttttgcagat caaaccgcat ttggtatccg
    31561 aataagctta atgtgcctgt gcctgttctg tcttctttac gatgcccttc ttccaacaat
    31621 tttcttccta agtcaagata cgcttgttcc atcctttttc ctcctaatct tctacccatt
    31681 cactcaagta ttcccaccgt gccatttttt cttcaagttg tgcttctgtt tcagatacgt
    31741 cgttttgcaa ttcttgtaat cgagtgaaat tatctccttg atgattcatc tcttcttgga
    31801 gcaatgagat tttttcttca agttctgcaa tctcatcttc aatcgtttcc cattcttttt
    31861 gttccatgta agataatttc ttcttttcag caggttcctt gctctgtatt tttggtttcg
    31921 ctttttcagc aggctgctgg gtctcttttt gcttcagtaa ataactggac atgtttccgt
    31981 aataaagttc ttgttttccg tttccttgga atactaataa cttatctgct accttgtcca
    32041 agaaataacg gtcatgggaa acagtgatca cagcacctgg aaaacttcta aaataatctt
    32101 ccaaaatcgt caatgttgct atgtccaaat cattggtcgg ttcatccaat aataaaacat
    32161 taggttgctg aatcagcagt ttcaacaaaa ataaccggcg tttttctccg cctgaaagtt
    32221 tgcctatcag tgtcccatgc ataaatcttg gaaataaaaa tcgttcaagt aattctgcta
    32281 ctccgatttg actgccatct gctgtttttg cttcttcagc agcttcttgt aagtaagcaa
    32341 tcatccgttt atctggtgcc atttcttcat tttcttgtgt ataatacgca agatgaaccg
    32401 tttcaccgat agacattgta ccgctatcca ggggaattct gccagctaga atattaagca
    32461 atgtcgattt tcccgcacca tttttaccag taatacctag tctttcccga gattgaatca
    32521 ataaatctaa atgttctagc agtgtttggt catttatacg gtaactgcca tctttgattt
    32581 ccagtacttt tttccctaaa cgttgtgtcg ctaggttcag ctctaaatca tcttcttggt
    32641 ttacttggta caagttctcc tttagatctt cgaaacggtt gatccgtgct tgctgcttgg
    32701 tgccacgtgc ctgtacgcca gccctcatcc aagctaattc ctgtttataa agccgcttgc
    32761 gcttttcttc ttgttctact tctacacgat cacgttctgc tttttctaag acgtaagctt
    32821 cataatttcc tttatactcg tataattttc caaatgaaag ttcgaagatt cggtttgcta
    32881 ctctatctag aaaataacga tcgtgggtaa ccatcaatag tgcgccacgg tattgtttca
    32941 aatagttttc caaccactcg atcgcttcat aatctaaatg gtttgttggt tcgtctagta
    33001 atagtaaatc gggttcatca atcaacactt gcgccagact aactcgtttt ttctgaccac
    33061 ctgataaagt actgattttt ttatctaatt cactgattcc taatttttgc aaaataatct
    33121 ttgcgttggt atctgtagtc caagcatctt ctttattcat ttgttcttct gctttagcat
    33181 aacgtttttg cacatcaggg tcttctccgt tttcccctag ttcgatcaat gcttcctcat
    33241 atgctcgaac agtttggatc aaggggctgt ttccttgaaa gactgcttgg agaacagtta
    33301 attcatcgga aaattcagct gcttgagaaa gataaccaat acggtaatca gttggataaa
    33361 acactgtttg ccgatcaccg tcgctgctat cgataccggc aataatattt aagagacttg
    33421 ttttacccgt cccgttcgtc ccaatcaacc cgatacggtc tttttcgtgg accaaaaaag
    33481 aaatctggtc aaacaaatct ttttcaccat aagttttttt gaggtcagtt acttttaatt
    33541 ctttcaacat gttccctcct tatcttggat attgtatcat aaaaatagtg aacttcagga
    33601 aaattttttt ggtatttgtt ctttttgtgt tctcaaaaaa agaacaggac cgattcgatc
    33661 ctgttctgat atgttttgtt ttttataaaa cttgaaaatt tttac
//
LOCUS       DAIGUC010000031        32224 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.031, whole genome shotgun sequence.
ACCESSION   DAIGUC010000031 DAIGUC010000000
VERSION     DAIGUC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.031"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(98..1228)
                     /locus_tag="NOB46_001568"
     CDS             complement(98..1228)
                     /locus_tag="NOB46_001568"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCI1058505.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="NOB46_001569"
     CDS             complement(1877..3079)
                     /locus_tag="NOB46_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1058506.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="NOB46_001570"
     CDS             complement(3139..3342)
                     /locus_tag="NOB46_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HCI1058507.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="NOB46_001571"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="NOB46_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="NOB46_001572"
     CDS             4879..5691
                     /locus_tag="NOB46_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058508.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="NOB46_001573"
     CDS             complement(6715..6867)
                     /locus_tag="NOB46_001573"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI1058509.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="NOB46_001574"
     CDS             complement(7058..7936)
                     /locus_tag="NOB46_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1058510.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="NOB46_001575"
     CDS             complement(7975..9093)
                     /locus_tag="NOB46_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HCI1058511.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="NOB46_001576"
     CDS             complement(9090..11189)
                     /locus_tag="NOB46_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HCI1058512.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="NOB46_001577"
     CDS             complement(11240..12061)
                     /locus_tag="NOB46_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1058513.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="NOB46_001578"
     CDS             complement(12058..12867)
                     /locus_tag="NOB46_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1058514.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="NOB46_001579"
     CDS             complement(12888..13382)
                     /locus_tag="NOB46_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1058515.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="NOB46_001580"
     CDS             complement(13394..13882)
                     /locus_tag="NOB46_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1058516.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="NOB46_001581"
     CDS             complement(13959..16655)
                     /locus_tag="NOB46_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1058517.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="NOB46_001582"
     CDS             complement(17083..18156)
                     /locus_tag="NOB46_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1058518.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="NOB46_001583"
     CDS             complement(18153..18980)
                     /locus_tag="NOB46_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058519.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="NOB46_001584"
     CDS             complement(18981..19787)
                     /locus_tag="NOB46_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058520.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="NOB46_001585"
     CDS             complement(19799..20884)
                     /locus_tag="NOB46_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058521.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="NOB46_001586"
     CDS             complement(20901..21443)
                     /locus_tag="NOB46_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1058522.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="NOB46_001587"
     CDS             21701..22690
                     /locus_tag="NOB46_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCI1058523.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="NOB46_001588"
     CDS             22687..23424
                     /locus_tag="NOB46_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HCI1058524.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="NOB46_001589"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="NOB46_001589"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HCI1058525.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="NOB46_001590"
     CDS             23988..24620
                     /locus_tag="NOB46_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1058526.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="NOB46_001591"
     CDS             24705..25352
                     /locus_tag="NOB46_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1058527.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="NOB46_001592"
     CDS             25357..26340
                     /locus_tag="NOB46_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HCI1058528.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26743..28257)
                     /locus_tag="NOB46_001593"
     CDS             complement(26743..28257)
                     /locus_tag="NOB46_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HCI1058529.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28395..29201
                     /locus_tag="NOB46_001594"
     CDS             28395..29201
                     /locus_tag="NOB46_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058530.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29376..29945)
                     /locus_tag="NOB46_001595"
     CDS             complement(29376..29945)
                     /locus_tag="NOB46_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058531.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30028..32088)
                     /locus_tag="NOB46_001596"
     CDS             complement(30028..32088)
                     /locus_tag="NOB46_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HCI1058532.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
BASE COUNT         9649 a         6750 c         5487 g        10338 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattatgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccaagacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 ttaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgcctt
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactggc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg atcaaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
    26401 aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg aaggaatttc
    26461 ttctgcttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
    26521 cccacgctct ttttccgaat aaacggtgtt caaaagcttg catctgcggt aataagtcca
    26581 accaagttaa aaacataaga agctgttttt acttggctgt tcttattact tgatgcaggg
    26641 cagctttttc acaacctctt cactaaacag tgttcaatca gctgaccctc ggtattagct
    26701 caaaacgctg atttcacaac ctctttttat ttacgttcta tttcattcat tttccgaagc
    26761 aaatcgagct gcttgtatgc ccgcttgtcg cccaaaaata atgatctccg caactgaatt
    26821 tccaccgatc cggttgtttc catgtaagcc acctgtgact tcaccagcag catataaccc
    26881 cctaattggc tggttttctt tatctaatac ttcagtgttc gtattgattt tcacaccgcc
    26941 catcgtgtaa tggattcctg gtgcgatttt gatcgcataa taattcggag acgataagtc
    27001 atgttccatg gctgtggcac ggttgaattg agcatctttt ttctccgcaa catccgtatt
    27061 ccatccatca actgtttttg ctagtgtttc ttttggtaaa tcgatttttt ctgctaattc
    27121 ttccattgtc tttccagttg tgacatatcc tttttggtca taaaattcaa tagctgtggc
    27181 acgatcacgc acgccttggt caaaaatcaa ataagctgat ttttcaggca atgctgtaat
    27241 tgctgcagat actttatccc ttgtatccat ttcattgaca aatcttttcc cctcttgatc
    27301 gaccaagatt gctccttctc cgcgaacaac ctcaccaatc aagaccccct catcctgctg
    27361 cacagttgga tgaatttgta ttttatccat atcaacggtt tgtccaccta atttttcaat
    27421 catggtgata ccatctccag ttgatccttc ttgatttgtc gtaatataat cagctaaatc
    27481 gggacgatat ttttcaataa attctttgct ggcaccaaaa ccgcctgtgg taactacgat
    27541 tgcttttccg gtgacctctt ttggttcttc tccttgaaca tgtacagtca cttcattgac
    27601 cgtttcccca tttttcttaa tgtctgtcac atctgcgttg acaaaaatag ggatttcccg
    27661 ctcatggacg ttattcaata acccctccac taagtatcca ccaatagccg agccatcaga
    27721 cggacgatgt gtcctctttt cactcatccc tccagtgatc gttaagttgt ccagtttgat
    27781 accgttttga tctagccaat cgaccgcatc agcagagtga tcgacaaagt atcgaagcat
    27841 ttctttatca ttcgttcctc caccaccttt tagcgtttct tcatagaagg catcattcga
    27901 gtctttgatt ccttcttctt tttgaaattt tgtttctgaa gcattcatac cgcttgatga
    27961 tttagatgtg tttcctccgg caacaggcat cttttccaaa attactggat tcaacccagc
    28021 atcttttgct tcgatagctg ctgccatccc tgcaccacca gctccaataa tcacgacatc
    28081 ataagattct ttcatttctt ttggatctgt atatacttgt tcagaagcgc ctgatgatac
    28141 ttcggcagat tccttcgtac tagaacttgt ctgcgctgta tttttctgat ctgcgccgca
    28201 tgcgctcata gcaagaagtg caacggctgt taataaacca gcaactaatt ttttcatttg
    28261 tatccccctt ttctccttat actatattaa gtgatttttt tcacaatatc aactctgttt
    28321 ttctttaagt catatagctt tggtaaacac acgcttctta gtataattaa ggatatacat
    28381 gaaggagtta ttttatgaat catttgaaaa ccttttttac gaacagtaca aaaactgcag
    28441 gtagaatcac aaacggaatc tatattttat tacgtatcat cgtcgttatt atgctagtgg
    28501 atcaggtctg gaaccaacac tggggaaata caatgctttt attactgaca ttaattttat
    28561 ttgaaatccc ttattttctg gaaaagatat taaagataca gattccaaat atgctagaaa
    28621 tcattttgtt atcttttatt tttagttcaa cagttttagg agagttaagt gatttttatg
    28681 gctatttttc aatgtgggat acttttctac atgcattcag cggattttta gctgggggtg
    28741 tcggcttttc ccttgtttat ttgctcaata aaaatacaaa aaccatgaac ttgactcctt
    28801 tattactagc agttgtttcc ttctgttttt cgatgacagt tggtgttatg tgggagtttg
    28861 tggaattttc agcagataaa ttactgcaat tcgatatgca aaaagatacg atcatccagc
    28921 aaatcaatag tgtggagtta agtaaagacg gaaacactgt ctatcatgtt ccagatatca
    28981 ctcggacaat cattgaaagt caaaatgcag atggtaaaac agataaaaca atcatccaaa
    29041 atggttactt agacgtggga atcatggata ctatgaagga tttatttgtt aattttattg
    29101 gagcagttgt tttcagtgta tttggttacc tctatagtcg aaacgattac caaaaattta
    29161 cgttcatcaa gaattttatt cctaaaaaaa tcaaacgata aaacatgcta aaaaacaaga
    29221 gaaggggcag tgacaatact tttgtcactg ccccttcttt tttgaatgta tggcatgcca
    29281 ttagttatcc gatagtatta actcaaaaaa gtaagatatg aggaatgact atttcgtttt
    29341 ttatcccaat actgaggact tatttcacca tttcgttatt tatctaattt acttaaaacc
    29401 tgcataactt tttcataatc tggattaggt gtgccgtcta gattttcagc aataaaagta
    29461 aaacccattt ttttataaag agcaatcgcc tgatggctcc atgtctgtgt gtgaagatag
    29521 attggtccgt ccgtatggag ggtaggaaat tcttgcaaga ctctggcagt caatgctttt
    29581 gcgagccctt ttccttggta atctggtttc actgctaacc aatgaaaaac cggatacact
    29641 tgctctcttg atttttttcg ccaagcggta caggttgcta ctttttctcc tttttttgtc
    29701 tctacaaaaa acatccttct ttcaagttct tcaggataag gagcaaagtt ttgttgaaaa
    29761 tactcaagtg cttcatctgt cgtttgaaat tccccaacgg aagtctcaat ctccgcccaa
    29821 gcagattcat cttctttttg ataaaatcga aattcaaaac cttccgctaa aggcgtgatt
    29881 ggaacatttt gttgaagtgg tcttgtcatc cagatttctg cgtaaggtaa cgttttatct
    29941 aacatttttc tatccctcct cgtctccatt atgccaaata acatatgact cagctactta
    30001 tttgactata acagatagag atataaatca gaaccagtca tctgcgtcaa attcatttcg
    30061 attagcgtat acccatgttc ctgccatacc tcgcatgaaa tctcctaaag cagaagaagg
    30121 aatacctcca ccaggtgcgg gtgttcccgg actaggaagt ggtacttgcg gctgcagatg
    30181 ctcatcggtg gaatcaatag ttgacaagcg ttttttcttc gtttccttct ggtcatctga
    30241 ttccttctga tcttccgact gtttagcaac aaattctttt tctgattgtt gttttatttt
    30301 aggctctaaa atttcatttt ccaatccaga aacttgtggg gccaaatgag cttcttgcct
    30361 tatcgtttta ttagattctg agatttttct agatattctt gctaactcta ggcttcttgt
    30421 ttgttttact ttccctgttg gagaaactgc atgagccatt tgttgttttt tttctgacaa
    30481 gctttcttct tgtctttttt gttctttttg atctatctgt ttgtttaatg gtaaaacatg
    30541 taatagtgac tgagcatgga gttcttggag tgaatacggg tcatgataac tatacataat
    30601 cgtaaaatca cctgtttgtt tggtcaaata accatcctcc aatggtactt cattgattgt
    30661 aaccgataca tcctttaacg gtacgggttt acctaaggaa tttgttgctg attggatcaa
    30721 ctcttctttg tttatttttt cgtttggatg aacaataaga tcatgacctt ctaatgaacg
    30781 attgtctggt atataaacat aagtaaaggt aatttcccct cctgattgct tcctattatt
    30841 catcagttct gagtgaagta cttcaaggat ctccgaccag tgactttttc tgtctaatcc
    30901 gtttgcttgc atccaatcag aaatagaagt gactttccca ttttgttcat aagtcgataa
    30961 atctatattt ggcactcgat cagaaaattc agcaggtagg cgcaaatcag gaatacgatt
    31021 tacactactc atatgtgttt ctgcttgaag ttctttattt gtttgactat ctataaaatg
    31081 agtgatgaca gtcgatgaag cagcagatgc ttctacataa actacagctg ttgtttctgc
    31141 cacatttgat gttttcgagt ctatataagt taatacaacg ggatattctc ccggagttgt
    31201 agtatctact gtcccgttca ttttgatttc ttctttattt cctgaagttc catcgctttt
    31261 tgttacatat tcaacaagat ctttaggggc gtaactctct cctgttctta agtgaagatc
    31321 ttttcctttg atagctgttt gatcagcacg aacatggatc acagcagatg cagtcattgt
    31381 ttttaaagca attggatcaa aataggacaa ggaaatagta gatgttcctg tattagtcgt
    31441 atccacgata ttcccattgt ttgaaattac tttggacata tctccttgtg ttccatctgc
    31501 gttcttcagc ctttctacca gatcagatat cgaaactttt gtccctgcca gaacatcgat
    31561 tttctttctt tcaaactgtg aataatcttt ttcatataca taagaaactt gtgcgcttcc
    31621 accgtccttt atatctgtca aagcatgatt caaaatatca gtgatctgtt ttaactgatc
    31681 accttttgta ggatcagtca tatcggaaaa gatagaaagc ggcacactgc ttccggtttc
    31741 cgatgtccat aatgttttgt taggaattaa ccagtagtgg tttatcgttg gaggataact
    31801 gactttatta taggaagtca atgcaggaag tagctgtttt ccatttgcat cagtgaaagt
    31861 atgagtaata gtgatagggg aatcagtggt ctcagaaaca gaggtacgta cgaccttgat
    31921 ggtttgtgtc gttgcctgaa cgggtacatg catatagaca cctacagata aactgatcag
    31981 catcgtgcgc atcataaact taacgtagtg tttttcagaa cacgaccgtt ccttatctaa
    32041 acgacaagcg tgtttattta gttgttttga acgtcttttt gaacacattt attcttagtc
    32101 ctccctactc ttgtctaaac atgaagtagt aattttcata agatgatttc attatataaa
    32161 taaaatcaaa agaagatgga ctattaggag agtatttttt ttgatttttt attgtttcaa
    32221 gaaa
//
LOCUS       DAIGUC010000032        31872 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.032, whole genome shotgun sequence.
ACCESSION   DAIGUC010000032 DAIGUC010000000
VERSION     DAIGUC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.032"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(293..760)
                     /locus_tag="NOB46_001597"
     CDS             complement(293..760)
                     /locus_tag="NOB46_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI1058533.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(880..2418)
                     /locus_tag="NOB46_001598"
     CDS             complement(880..2418)
                     /locus_tag="NOB46_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCI1058534.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            2498..3184
                     /locus_tag="NOB46_001599"
     CDS             2498..3184
                     /locus_tag="NOB46_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCI1058535.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(3385..3912)
                     /gene="msrA"
                     /locus_tag="NOB46_001600"
     CDS             complement(3385..3912)
                     /gene="msrA"
                     /locus_tag="NOB46_001600"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI1058536.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(3996..4673)
                     /gene="pgmB"
                     /locus_tag="NOB46_001601"
     CDS             complement(3996..4673)
                     /gene="pgmB"
                     /locus_tag="NOB46_001601"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI1058537.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(4670..5800)
                     /locus_tag="NOB46_001602"
     CDS             complement(4670..5800)
                     /locus_tag="NOB46_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI1058538.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(5800..7983)
                     /locus_tag="NOB46_001603"
     CDS             complement(5800..7983)
                     /locus_tag="NOB46_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI1058539.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(7980..9005)
                     /locus_tag="NOB46_001604"
     CDS             complement(7980..9005)
                     /locus_tag="NOB46_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1058540.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(9050..9877)
                     /locus_tag="NOB46_001605"
     CDS             complement(9050..9877)
                     /locus_tag="NOB46_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI1058541.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(9874..10941)
                     /locus_tag="NOB46_001606"
     CDS             complement(9874..10941)
                     /locus_tag="NOB46_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HCI1058542.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(10967..11803)
                     /locus_tag="NOB46_001607"
     CDS             complement(10967..11803)
                     /locus_tag="NOB46_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058543.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(11800..12669)
                     /locus_tag="NOB46_001608"
     CDS             complement(11800..12669)
                     /locus_tag="NOB46_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1058544.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(12739..14022)
                     /locus_tag="NOB46_001609"
     CDS             complement(12739..14022)
                     /locus_tag="NOB46_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI1058545.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(14036..15721)
                     /locus_tag="NOB46_001610"
     CDS             complement(14036..15721)
                     /locus_tag="NOB46_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HCI1058546.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            15996..17021
                     /locus_tag="NOB46_001611"
     CDS             15996..17021
                     /locus_tag="NOB46_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1058547.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(17616..21290)
                     /gene="rpoC"
                     /locus_tag="NOB46_001612"
     CDS             complement(17616..21290)
                     /gene="rpoC"
                     /locus_tag="NOB46_001612"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCI1058548.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(21348..24965)
                     /gene="rpoB"
                     /locus_tag="NOB46_001613"
     CDS             complement(21348..24965)
                     /gene="rpoB"
                     /locus_tag="NOB46_001613"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI1058549.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            25693..26661
                     /locus_tag="NOB46_001614"
     CDS             25693..26661
                     /locus_tag="NOB46_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1058550.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            26679..27584
                     /locus_tag="NOB46_001615"
     CDS             26679..27584
                     /locus_tag="NOB46_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058551.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            27581..28387
                     /locus_tag="NOB46_001616"
     CDS             27581..28387
                     /locus_tag="NOB46_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1058552.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            28523..29512
                     /locus_tag="NOB46_001617"
     CDS             28523..29512
                     /locus_tag="NOB46_001617"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCI1058553.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(29829..30353)
                     /locus_tag="NOB46_001618"
     CDS             complement(29829..30353)
                     /locus_tag="NOB46_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HCI1058554.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            30640..31872
                     /gene="scm"
                     /locus_tag="NOB46_001619"
                     /pseudo
     CDS             30640..31872
                     /gene="scm"
                     /locus_tag="NOB46_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
BASE COUNT         8956 a         6898 c         5998 g        10020 t
ORIGIN      
        1 gtcttgtcac aaccccttat tttgaataaa cggtgttctc ctgccaactc ctcggtcaca
       61 agtcacaata tccataaaac ataagaagct gttttttaaa attgtttctt gtgactcgga
      121 gctgaacggc aggcttacaa cctcttggta aacggtgttc aatcagctga ccctcggtat
      181 tagctcaaaa aacggcaaaa tatgaggaac tattttgacg tttgtttctc taatactcag
      241 gtcaaaacgc tgatttcaca acctcttttt cggtcaagtt caacaacagt ttttacgcgt
      301 cgatctctgg cgctttgccc aaatgagctt ggatcatcca gatacgtttt tctgtggctg
      361 ttttgaattc gataaagata tcttgtgttg gatcgtcgcc ttcttctcca gaaacttcga
      421 ttcctttttg gtaaagatct gctagataac gatagcctgc aacaagtgtt tccaaacgtt
      481 ctggaatagt acgatcccag cggccaattt catcagggat ttttgtgtta tctgcaaatt
      541 cacgcaatgt agaataaggt gaaccgtcta atgtgatcaa gcgttcggat acttcatcta
      601 actgagcgtt caaatcatcc atgaactcat ccatcattgg gtgcaatgta aggaaacctg
      661 gtcctctcat gtaccaatgt gtttggtgaa caacaacaga catttggctt agatctgcaa
      721 ctaattgatt taatacttct ttggtttgtt ggaatttcat ctttcttgcc tcctaacatt
      781 ttcttacact taaaataata gtagactttc aatgaaaagt acaacaaaat catttacctg
      841 agaacgattt tcagttcgct tttttatccg taaagccaat catttttcag aatcagctaa
      901 ttcttctcgc agttgagcaa attgctgata agtctgtgct aaatgctttt gtgtcgaaac
      961 aaataatgga tagattttct gatatttttt atgatcagtt tcttgtactc caacttgctc
     1021 tttcaattct atcaattcct gtgcttcact gatactttgg atctttccga tgcttctcca
     1081 gcctaaaatc acagctccta atgcggatgc ttctgtgaca gtagggaaaa caagcgggta
     1141 acccagtaca tcagccatca tctgacgaaa aatcggagat tgagcaaacc cgcctgtagc
     1201 acggatctct gtgagctgat tttcctggca aactcctttt aaaatccgat aaaggttgag
     1261 acagatccct tctagaatcg ccttcatcat ttctttttct gtatgttgcc gctgtaaacc
     1321 gataaaactg ccaaacgcat ctgcgtccca aagcggtgct cgctcaccaa gtaaataggg
     1381 atgaaaaatc agaccattgg cacccgctgg cacaaaagcg atagccgaaa gcagtgcatc
     1441 atatggattt tctccttttt ctttagcaga ttgaacgact tcctgtaaaa atgtatgccc
     1501 tgcccaatca aagatgccag caccattgct agtcgctcct cccactaccc aatgtttctg
     1561 atccagaaca taacaaaacg tctccatttc tggatggaac tgaggctgag tagtaataaa
     1621 acgaagtgct ccgctcgttc ctacggtcaa agcggcgatc gtatcaccaa aagcacctaa
     1681 ccctagatta gaaagcggcc cgtctgcccc tcccaaaaca aatgatatat catttggcaa
     1741 acctagttct gctgctgttt ttgatggtag acctgttact tgataggtgg aaggaaagac
     1801 ttgcggcaat tgctctattc gaatgttcaa gtagtcaagc acttcttctg cccattggaa
     1861 ttcatggata tcaaaatatc cagttcctga agctgttccg tagtcgctga tcagttcgcc
     1921 aaacaatcta taaaagatat agtctttgat accgacaaaa taagcagttt ttttgaataa
     1981 ttcaggttgg ctgttttgca gccacttgat tttgttcaat ggtgtcattg gatgaatcgg
     2041 cgtcccagtc tgccgataaa attctttgcc aagcacggta tatttcagtt tttctgcttc
     2101 gtccgctgct cggttatctg cccaagtgat cattcgagat aacggtgttt tctcttcatc
     2161 caacaatatc aggccatgca tcgcagagga gaaggagaca aattgaatga ttgtgtctga
     2221 aggcaactgt ttaattactt cttttataac ggtgcagaca ccttgaaaga tcaattcctg
     2281 atcttgttct gccatccctt gtgtttcttg gatcaaaggg tagcgaaaat aagcggatgc
     2341 tgcttcttgg gcttcatctg tgaaagcaac tgctttggtt tgtgtggttc cgatatctaa
     2401 tccgattgaa acgttcattt tttcacctca aattttatgt atgtacaaaa atttagttta
     2461 agcttgcgta tcttggtttt gaaaaggggg agatggcgtg ttactttatt ttatcattgg
     2521 ttgctgtatc ggatcatttt tatgtttaac cgcccagcgg attccgttag gtcactctat
     2581 tatttatcct agatctcatt gtgtcaaatg ctgtcgttcg ctttcttggt atgaattgat
     2641 tccgattctc tcgatcatcg tccaacgatt tcgctgccgc tattgcaggt gtcggttgcc
     2701 cttctactat ttgttggcag aagccttatg tggtggtctt tttgcctggt tctttacttt
     2761 ttcttccgca agaaattttt cgacgttcat atggatgctt tcggctttgc tattttcgtt
     2821 gatggattta ttttacttca tggtccattc tcacacgcta ttctgttctt gggcaatttt
     2881 atggattttt tggttgcagg ccggcgtctt ccaatggcaa agtgtgctgt taacgtttat
     2941 cgtaggcggt gtgtgccttc gctatggtca atcctatctc ggagctggcg atactctgtt
     3001 gatgctttct tggagtggtg gcttgtctct agaagagttg cttcagatct tgtttcttgc
     3061 tagtctgttt ggaatatccg ttttttctgt ttactttatc tgtcataaaa aaaagttgga
     3121 aaagctgcct ttcattcctt ttttgagcag tgcgttgctg attgtccttc atcttaggta
     3181 ttgaaaaaag gttgtgacaa acgacttgtc acaacctctg atatatagtg ttctcttacc
     3241 aaatccttgt gacttggagc taggcgacag gttcacaacc tctccactaa atggtgttca
     3301 atcagctgac cctcagtatt agctcaaaat gctggtttta caacctctga tatacggtgt
     3361 tccataagta gctttttcgg cttcttattt cttgacgccc caatgtcgac gaaggaaacc
     3421 tgcacgtcca gaaccttctc gataaagatt gtaatggagc ttgtttttct tgtaataatc
     3481 ctgatggtaa tcttctgcag gataaaattc gcttcttggt tcgatttttg tcacgattgg
     3541 cttatcgaat cgcccgctgt cttgcaatgc ttgttttgaa cgctctgcaa tatttcgttc
     3601 ttcttcatca ttatagtaga tcactggacg ataagaatca ccgcgatcag cgaactgtcc
     3661 taatgcgtca gtcggatcgg tttgctgcca atagatttcc accaactgat cataagaaat
     3721 aacttctgga tcatattcga tctctactgc ttctgtatgc cctgttgtgc ctgttgttac
     3781 ttgttcataa gttggatttg gtacatgccc gccagtataa ccggatgtca cagaaatgat
     3841 ccctggctgc tcttcaaatg gtttgaccat acaccaaaag catccgcctg cgaaaactgc
     3901 tttttttgtc atataaaatc cccctttttt ctcatcatac cttgatttcc aaaaggagga
     3961 taacgttttg cttgtgacag aaaaaacgga aactattata tacgtgatac ggcttctgat
     4021 aaatgccaaa acgaacgtac ttgatcaaaa acggttaaat caggaatcac atattcagca
     4081 gaaggaagat ttatgttttc acctattccc aatacatgca tgttaccagc caaagctgct
     4141 tgacaaccag cttctgaatc ttcaatgacc aagcatgcat ttggcggtac attcaattgc
     4201 tgtgctcctt tgagaaaaac ttctggatca ggttttgctt ttgatacttg cgtgccgtca
     4261 ataaggacat caaaataact tgtcaaattc gttttttcta aaatgaggcg tgcatttttg
     4321 cttgctgatc ccaatccgat cttgatgttt gtttttttca agtactcaag aacagctatt
     4381 gcaccaggca aaacggatgt ttcatccatt ttttgaatcg cttgaagata tagattgttt
     4441 ttttgctcag caaaggctga tttctctttt tctgagaatt tctgttccat ttttccaaat
     4501 gacagcaatc gctctagtga ctcggttctg gatattcctt tcagttgctc gttttctttc
     4561 tcagtgaatg gaatggacag ctggttagct aaaaccagcc acgcttcgta atgataacga
     4621 gctgtgtcta caagaacgcc atctaaatcg aatagtgctg ctttgatttt catcgattac
     4681 ctccttgaaa atgaacgact tgaagtaaag atgcgatgtt tttagctgtg cgatgaagat
     4741 tatcagtggc ttgctgtaaa gcttcttgta aaggcacagc tgcaggaagg atcggaaaaa
     4801 cggccgaaat gccaacatct gctgcttttt cgcttccttt accaacactt ccgcaaatag
     4861 ctatcacagg aacgccctct ggtactcttc tagcaatccc aactggcgct tttcctttta
     4921 gactttgtcc atctagacgt ccttcgccta cgattacgag gtctgcttgc tgtacccgtt
     4981 tatcgaactc cagtaaatcc aatacgtagt cgatgccaga gactattttc cctgaagcaa
     5041 atgctaacag tcctgcaccc attccaccac cagcactact gcccgatgcc tcgattactt
     5101 gaggggcaaa tctcatataa aaatcatgca tggcttggtc agccactgct aattcatttt
     5161 ctttcaagcc tttttgtggt ccgaaaacaa aagaagcgcc ttcttttccg cataaaagat
     5221 tagtaacatc agtaatgaca gtgattttgg ctttaatcag ctcaataggc acgttcgttt
     5281 tatcaactgt agcaatttta cctagatttt ctcccagtgc ttctactttt tgattatctt
     5341 gatcgtaaaa agcataacct agaccttctg ccatgccgat gccgccatcg ttggtactac
     5401 ttccgccaac gccgatgatg atgtgtcgaa caccttgttg caacaattgt cgtatcagtt
     5461 ctcctactcc tcgcgtggat aacctaagtg gctgttgttg gtttagtggg acatctttca
     5521 atccgacgat ttctgccatt tcaaaaatcg cagtttgacc gtctgaagcg tactggattt
     5581 ctttgttttt gccaaatgca ttagtaacga ctgctgtttg ccgcttcaac cttaaactgt
     5641 ctgctaatga tgaaaccgtt ccttctcctc catcgcctat aggtagcaga tcatattcag
     5701 cctgaacaaa aacttcttga aaacctgatt gaatggcttg tgctgcctct aaggctgtca
     5761 gactttcttt gaaagaatct ggcgcaatca gaatacgcat tattttcccc tccgttccaa
     5821 gatcagttct ttttccagct ggtattggtc tccattgaca aaaataggta atgtttcttt
     5881 cgtctctttt tttattacta tttgtttttt tgtcaaaaca aatagcaacc tgtgattttt
     5941 ccaaataaaa ggaaaagaaa ttttttccca tgctgaagga agtcttggag aaatagaaag
     6001 agttccattc gttactgtaa tacctgaaaa accaaatata actgctagcc atagtgctcc
     6061 taatgaagca gcatgaattc cgtcatctga tgaatgcgga tctggtccta aatcaatcag
     6121 gcacgcttct tggaataaat gatacgccca ttccatttct tggatacggc aagcctctat
     6181 ggcgtgaatc gctttactca acgatgagtc gtggattgtt ttgttttcat agtaatgcaa
     6241 attcttagaa acgattggtt gagaaaaata ctcaggtaat aagtataaca gcatgacaag
     6301 atctgcttgc ttgctgactt ggagttcatt tacttcgcta cgggcataat caagtaaaat
     6361 agactggctg ccaggacgtt ctttgtaagt ggtcaaatca ataactggct tactgagata
     6421 cgtgtcatct tgcggaatca gctgttcttt gttaggcact ggcaaatata acttatctaa
     6481 aaaattttga cattctttca aaaaaagcgg atcgccagct tgatatttaa cagctaaggc
     6541 cacattataa tgcgccagat agttcgtata tgcattattg tcgatatatt ctgtgtattc
     6601 atctggacca atgactctgt gtatctctaa atgatcatcg acttttacag ctctgctcag
     6661 ccaaaaagct gctgtttcat gaatgagcgt ttttcccttt gtttctaaaa acgattgatc
     6721 ctctgttgct tggacatact cttgaacggc ataagcaagg tctgcactga tatgatgttc
     6781 tgcggcagct gaagcaactt cttgtcttgt tccggttttg atattcaatg cagcaaattt
     6841 gggtgtctct tcctgaccag tgtgtgcgct ttcccatggg aaaagtgcac cttgatagtg
     6901 ataatctctt gctttttgcc gtgcgccttc taatcgatca taacggtaca gcagcaaatt
     6961 ctttgctact tcaggaaact gatataaaaa gaaaggcagg ataaaaattt ccgtatccca
     7021 gaaaacatgc cctttataac cttcgccagt tagtcccttc gcccctacac taacacttgg
     7081 atcattgcgg ggagtcataa tctgtaaatg gtaagcagcg aagtccatcg ctaactgatc
     7141 gaaagaagaa tcgccttgga tcgttatccg atgctgatgc caaaaatctg tccaataaga
     7201 catcgactgc tctaaaattt ctgtataact aacgcttttc tgggcttggg caatactttt
     7261 cttaaacggg tctgtttgct gaagagaggt agagagcacg atgatcttct ccagcgtaaa
     7321 ggacgtattt tttctgatct tttctgaaaa ggaagcggtg atccggcgat tttttgcttg
     7381 gaatacacct gctttattga atttagctgc aatcccaata tcaattttac tttctgttgt
     7441 ctggtaggat gcactgatca aatcgtcacc aaatactcgc agttcttttt caaccaactg
     7501 ctgtgtacca aaattggttt gctgtccatc gatacccgtt ttcacatcta cttggcagtc
     7561 ttcggtcaac ggcttgatga ccactttcag ggctgcctga tggagattat tttgatcagc
     7621 aacacgacaa gtaatgactt ccactttttt tccttgagca gtttcaatga gcgcatagcg
     7681 tttaagctct cccatttcta aatctagtgc ccgctcgtat gcaagaactt tcatcgtctc
     7741 aagagaaaaa tgttcaccgt cgatttttat ttcccatctg atgacatctg ggagattcac
     7801 taactcggct gattctgctc ctaaaggtcg gttatataca ccagctgcaa acattcccct
     7861 tacttgattc cgatagtctt cctcctggct tcctctgata ccaaaaaatc catttccaat
     7921 ggtcatctga ctcgcatact tattgatata ctctaaatca aactgttttt cttctacttt
     7981 cataaggtaa taacttctcc tgtttctgcc gaacgatata aattttccac cagattctgg
     8041 atgacatatc cttgccagcc atctgcaatc atctgagtct ggtcaccgag cgcccgattc
     8101 acaaaatgag ccatacttag ttcatgtggg tcattaactg gcgtggtctt ttgtaaggaa
     8161 accagctttc catctacatc ttcgaatagt tcgcctggat acagattagc acctgcctga
     8221 tcgccacaaa aagccacatt cagtttgtct tctctgatat tcaaagcaaa cgaagtattc
     8281 agttggatga tcttgccgtt ttctaattcc agtgtgccaa aaattgcatc ttctactgtg
     8341 aatttgcttg gatcccattt cccgaatttc cctgaatttt ttttcgtacc aattttttgg
     8401 aagctgtacg cccgaacgct ttttacttta ggaaatccag taatatacat cgctgtatca
     8461 agcatgtgaa tgccataatc gatcaaaggc ccgcctcctt gaagttcttt gtcgataaac
     8521 gttccccagc ctggaacacc agaccgacga agcgcattcg cttctacgta ataaatatcc
     8581 ccgagaacat caagatgatt cttgatcatt gttgcttcgt cagaaaaacg atgctggaat
     8641 ccataagcca aaatctgccc gtttttatcg gctgtctctg ccatctttct tgcttgatca
     8701 gctgtcatag ctggtggttt ctcgcacatc actgaagcat tagcttcgag ggcagccaat
     8761 acatgttcga agtgaaagcg attgggtgta cagacactca cgatatcggg agaaatctca
     8821 ttcagcattt gtgtaactga tgtatacgca tgagaaaatc ctgtacgtcg gcaaaagtct
     8881 tctgctcgct ggctgactgg atcaaccaca gcggccaatt ctaagacatc tgatcttttt
     8941 tgataataag cagcatgtac tttttctgct acttgtccag cgcctatgat tgctactttc
     9001 ttcatttatt tctctctcct ttgcttattt acttattgtt attctttctc tattctttct
     9061 ctaaatcatt taaatgacgc gctgtttcca gacagttttt caagtattgc aatgattcct
     9121 gataaatttt cacttcattt tctcctcgca aacgacattc atataccata taaccttcat
     9181 actcattttg aagtagcgtt tgaaaatggc gagtaaaatc aattgcgcca gatcctggtt
     9241 ggtagcgatg attatctgct aaatggatat gacccacata ctctttttgc gtagtcaatg
     9301 cttttgaaat atcatcttct tcaatattca tatgataaaa atcagcgatg atctgcacat
     9361 gtttcaattg attagagtca atgtaatgac gcgcatccgc taacaaattg atcatatggt
     9421 cttggtatcg gttcaaaggc tccaaataaa taaccgtacc tgtttcttcg gctactttat
     9481 ctaaataacg aagtgattcg ctgactgctt tatagtctcc ttctttgctt cggggtgaaa
     9541 ccatcggcgg taatcgataa gtgaacattc cccaagctgc tgggataacg attcctttgc
     9601 ctccaacctc gcttagtgca cgcaaaatct cagcaatttg acgtacacca ttaagacgcc
     9661 gttcttcgat aaagtcaccg atccacccat cgtagccgtt acaagctgtc actactggga
     9721 tccctgtttc tttgattgcc tgtttgactg tgtcgatatt ttctattaac aacttaccgt
     9781 cgatttcgta ttcttcaaat ccacagtctt tgataaatct aaatttttct aaaatgtctc
     9841 ttgggaaaaa tgcttgatct tgcgtaccga atttcattgt tctcctcctc ggacttgaac
     9901 gcccattttg atactttctt ctgggtgctg gtctacataa cgcatgtaag cttctgcgct
     9961 ttctgcaaat ggcacaactg gatcaatgat ttcttcacaa tccaagtaac cgttcatcaa
    10021 taattcccaa catgtgtcct cgattcgttt acggttccat cttgggtaat ctgggtttgg
    10081 ttcactagat gctcgagcaa agacgatttt tgcattattg aaatgtgctt cgcgaccaag
    10141 attaaaccca gctggaaaag gtttagcaaa ggcaacataa gaaatgatcc cgccatagcc
    10201 gatccctatt aaagaagctt gtaatgcggc agcactgcca ctcgtttcaa taactgaatc
    10261 tactccacgt ttatctgtca attcctttag acgaaaaccg acatctgctt tcataggatc
    10321 tagcgtgtaa tcggcaccgt gtttttctgc taattctcta cgctgcgcta tgggatcgat
    10381 cccaacgatg gtagtagcac ctgctttttt agctaattga atcgcaattt gcccgatagc
    10441 gcctaaaccg aagattgcta cagcatcacc tgctcgaaca tgtgcttccc ggataccacc
    10501 taaagcgaat tgagcaggat cgtaacatac tgcatttttc cattgatcca accgatcaag
    10561 tttacgtagt ttataattat caacaccgtt tgtaatcagc gtttcacgaa tgggtccata
    10621 agtgcagact aactctcctt tttgatactc tgtcaccaaa ctgcccgttt cttcgatcgt
    10681 accgacaatc atatttccta attgaaattc gccaaatacc acaccgcgtt ggcttccttc
    10741 ttctcttggc aagaataggc gccattcttc tgaaaattct tcatcgataa atggacttaa
    10801 tcctctaaag tcgacaattt ctgttcctgg ttttggagta gcgaaaatta ctcggatacg
    10861 tacttcgttc ttttcgatct cacggtcttc gtaatctttg aatccggcta ttcttggttc
    10921 taatgcaact aattttttca tcttttcttt cctctttctt ttctttttat ccttttacgc
    10981 cgccttcgac taaatcacct ttaataaatc gttcagataa cgcatacata atgatgactg
    11041 gtaaagcggt caccaatgaa gcggccatca ttcgtcccca aatgtagtct ggtgtactga
    11101 ataatgtgtt caaaccgatt ggtaaagtaa atttttcgga ggtcgacagg aaaatcgaag
    11161 caaataaata atcattccac gaaaccataa agcaataaac gaagacagaa atgattccag
    11221 aaatagccaa tggtataatg atccgaataa tgatctggat ccggctaaga ccatcgatca
    11281 ttgctgcttc ttcaatatca gtcggaatcg tgtcaaaata actttttagc atgaatatcg
    11341 cagtaggaag tgtttgaacg accatcgtga taatcagtgc tgtattggta tcatacaaac
    11401 ctagaccgga aatgatttta aataatggaa caacgatcaa aataccggaa aacatataaa
    11461 cggtgtaaaa gctagcattg attttcgagc gagctttgaa gcgtagtttt gacaaagcgt
    11521 atgccccgct gatcccaatc actactgcag ttacggaggc tatcaaggag atcactaaac
    11581 tatttttgaa atacatgatg aatggaaaaa tctcagcatt gaaaatatcc tgataatgtt
    11641 caaaagtcca ttctttcgga aaaatagttt gtgtcgttgc aattgcttct tgtgaatcct
    11701 tgaatgatgt catcagcatg atcaaaaatg gaaacaaatt gacagctaat agcaacaaaa
    11761 tcgtcgcgta aaataagatt ttcctgctct ttttattttt catttcaagt ccaccttctt
    11821 tcgtgagagc aagacgaccg ctgcaataat gatgaacaat agaatcgata tagctgctgc
    11881 ttttccaaga tcattgaacg caaaggctgt ctgatacaaa taaacgccta agatattgac
    11941 tttattcgtc agtagataga catctgtaaa catatagaac atccagatag atcgtaaaac
    12001 aatcacagtt gctagtactg gtttgattgc cggcagtgtc acgatcttga acttctgcca
    12061 agcatttgca ccgtccattt cagctgcttc ataaagcgtt ttgtcgactg tttgcaaaat
    12121 agccaaaaat gaaataaacg catacggata gtatctccag atagcaaaca aaacgaccat
    12181 aaagaagcta gcaactggct ggtcgaacca cagcggtgct tcgttgaaaa gctgcaacct
    12241 atctactaac agatcattga cgattccata actattattg aacatatatt tccaagcaaa
    12301 aatcaaagaa atagatggcg taacataact taataaaatc agtgaacgca ccgttttcct
    12361 aaatctgaac ttgcggttaa gcaaaatagc tacggctaat cctaaagctg tactgcctgc
    12421 tacaactaag aatgtgtaag caactgttaa acctaaagaa cgataaaatt cactatcact
    12481 taaaatttca agataattgc ttaatccgat aaaaacggcg tctgagttag gattcagcgg
    12541 catatcgaaa aaactgatct gaatattgga aagcattgga atcagcacta aaacagctaa
    12601 taaaagcatg cttggtgcta aaagtcccat ggctaatttt aagtcagaat gtttccttgg
    12661 acgattcatt gaaacctccc cctgataatc tgccaatagc tatctacttt tttcgaacac
    12721 cattggcaga acttcttgtt atttcgtatt tttttgtgcg tcagctaaag cttgatcgac
    12781 atcttcgttt ccgacagtta cttggttcac tgcttttccg atcacacctg agcttgtgat
    12841 atctcccatt ttcgtgaaat tcttttcccc gactagtcca aagacttgta cttcatcaaa
    12901 agcactagca atctcagatg gcagctcgcc aaaagacttg atgacttcat tttctttgta
    12961 accatccagt tcgactactt gtttattcac tggttgagca ccaccaggag acatcaagac
    13021 ccacttttcc atgtttttcg gttgagataa gaaagctgtg aatgcttcag cagcctcttt
    13081 ttgtttctcg tctagaccag aagaaatcgt caatccagat actgtgccat agacagcttg
    13141 atctttttgt gttgggatag caaaaccgat attttctgag ttccccgctt cataaacaga
    13201 aggcaaaatg taagttgaat agattgccat tggtgctgtt ccattcatga aagcatcttt
    13261 gatttctgtc acatcattag agcctggcat cgtgtattgg gataagtttt gataaaacga
    13321 caatgcttct ctcatctttt ccgtatcgat cgttacctcg ccttcatcat ccaaaacatt
    13381 tgctccattt gacaaagcaa attgagagaa cgcttgctca ctcattgttc cttcagcagt
    13441 aggcatagca attccatatt gtttattctc tttatctgtg aaatgttgag caatttttaa
    13501 aatatcatcc caattttctg gttctgaaaa accagcttct gataattttt ctttgtcata
    13561 ccaaatacct tgaacccagc cgctaattgg tgcagcaata tagctttttc catcttctga
    13621 acgaacaagg tttttggctc cgtcataata attatcttct ccagcttcct cgataacgtt
    13681 ttggactgcc gtctgatcaa tcagttcatc tttatccatc actttagcaa aatcctgact
    13741 gacttccatt acttctggta atttaccgga acgagctaac gtaacgattt ttgtattgaa
    13801 cgctgattct tctaccggca cttgcttgat tttgatgtct ggattttctt tttcaaaatc
    13861 agcaaccagt tcattgatca cacttaatcg ttcctgttcg acagaagagt gcatgaattg
    13921 aatcgttgtc tgttgtgatt cgttagagct ttgactttca ccacaagcag taagaagaaa
    13981 tccagtagct agcagacagg tagtaacaat aatttttttc atttttttcc acctcttatt
    14041 ttattatttt cagccacata tattcatacg gctggaatat caactttcgt tcttgactgc
    14101 aatggataat ttgtccagaa aacaggtcta ggtaatctcc ttttggtaaa agataacctg
    14161 ctgattgatt ggaaaaatta tggataacta agactttctc ttccttcgct tcgcgaataa
    14221 aactgataaa agaatctgct gagtccagta agtaaatcaa actattcgga tggaaggctt
    14281 tttctttttt tcgaatagat agcatctggg tcaattcacc atatactgct gttcttaatg
    14341 gatctgtctg caactctttc tcaatatctg ctaacaaaaa tttttgccga ttgatttttc
    14401 gattctctcc tgttttttct acgcctttgt aatcatttcg acttcccagc acactttgaa
    14461 tataaattgc cggcacgcct ggtaacgtta ccaaaaatga atgagcagct aaaaagcgtt
    14521 tgcttctcca ttccgtcgta tctgttggag aacttaacgc atctagatac gtagcgttta
    14581 tctcatatgg actggtcgtt ccatctgggt ttttcttgta gtttactcgg gcaccctctt
    14641 tcttcagctg ttccactaat tcaaggatcg ttttttccgg cagaatacct cgtaccggat
    14701 tcaatccgat accgtcatgg gaggctaaaa aattaaaaaa agttgttttt ttcgatgcga
    14761 aatcgatggt ttttaaccat tctttcaact tacttgtatt acccgaacga atcgcttgaa
    14821 gggtcaaagg tggtagcgaa aactgataga ccatctgtgc ttcattctcg ccattcccaa
    14881 aataactgat attatctttg tgtggcacat ttgtctcagt gatcaatacc gttcctggag
    14941 ctgcttcatc agcgattgca cggaataatt ggatgatttt atgcgtttct ggcaggtgta
    15001 tacaagaagt tcctagttct ttccataaaa atcccacagc gtccaagcga ataaatgaag
    15061 cgcctttttc taagtaaaac aaaagaatat cgatcatttt caataaaact tctggatttt
    15121 taaaattcaa gtctacttga tcttcgctaa aagtcgtcca tacgtgtttt tctttcccgt
    15181 ttttgtcaat gaacgttgta agtaacgggc tggtccttgg tctagtcacg ctgcttgtat
    15241 ctgtatccag tggcaaatca ataaaaaaat ctttgtacgt atcattcaag tttaaatatt
    15301 cctgaaacca agtactttcg gcagacatat gattgcagac aaagtcgaac attaaccgtg
    15361 tttcgcttct catttcttct atatcttccc atgtgcccaa acggtcgttg attgcctgat
    15421 aatttacaac ggagaaacca tcatcagatg tatatgggaa aaatggcaag aaatgtacaa
    15481 ctctaaatgt atctgccaaa tacttttgat aaaatttctt aaatgtacgc aaagttggtt
    15541 gctgctcttc aaaaaattga tccccataag taatcaagaa aatatcttct tcgtcccaat
    15601 gcagtttgcc tgcctggcct ttcttctgct gataaacact gactttttgt tcaatcatag
    15661 aggcggtttt ctcagacaaa tctgagtcgc gataaatcgc ttgtaaaagt tttgtataca
    15721 tcggattccc ctttcttttt tgggagcgtt cccaacgatt tgatcatatt atggaaaacg
    15781 cttactgtca atagcatttt tttaaataat tttgatatac acaaaaatac aaataagaaa
    15841 gcttatgtat caataattaa tagcttctta aaaaaatatg gtctctcatg atcatgcaag
    15901 ctattcctaa attttcaaaa tcatagacaa aaaagaatgt ctattgtact atggaattat
    15961 tctaaaacgc tcccaaaaag gaggtgcata taaaattgaa acctactatt tatgacattg
    16021 cgaaaaaagc taatgtctca aaatcaactg tctccagagt attaaataac cagccaaata
    16081 tctctgataa agcaaaagca agtgtacttc aagcaatcaa agaattgaat tatgaaccga
    16141 gcaaaattgc aagaggactg tcaggaaatg gttttgacgc gattctagca ttatctcatc
    16201 gtacttctca tacgacctat ggcaatcctt ttttttcaga tgttattcaa tccatttctg
    16261 ccgtttctga acaaaataac ttcgacttga ttctacaaac ggcaaaaaca ccagaagaag
    16321 agctagaaaa atgcgcgaaa aagatccaag aaaaaatgat ccgaggaatt attattttaa
    16381 gctctacgat ggatgaaaca cttctttttg aattggatca atacaatatt cctattgtgg
    16441 taatcggaaa agtcggaaac gactacacga acatctactc agtggacacg gataatttcc
    16501 aggatagtta cgatttggtg gaaacactga tcaagaatgg acaccgtcat atcggctgtc
    16561 tccatgctcc gacagaagtt tatgtatcca atgatcgtct caatggttac cgtcaatgct
    16621 tatttgatca ccacctagat atccgtaatg aatggattat agacggcggc tttcgcttag
    16681 aagatagcat ggcagcaatg aatgatttaa tgaagctacg agaaagacca actgcgattt
    16741 tttctaccga tgcattaaaa tcattgagta tttacaaagt ggcagaacaa tctggaaagc
    16801 agatacctga tgatctttcg atcgcaggat tcagtgatcc cttattgtcc tccctatttt
    16861 cgccacagtt gactcggata gacattccga caaatcagtt aggaatcaaa gccacagaac
    16921 ttttattcca actaatccac caccaatacc ctgaagaaaa aagaatcatt ctttcaaccg
    16981 agattactct cacagattcg atccaacaac aagaaatgta gaacagaatt ataaaagaac
    17041 agaaacactg aggataagtc agttactctg ttcttttttc aatcactcat ccctcgttac
    17101 cccctcccgg tattttagcg aatttttctt attttccatc tgttttagat agctgtggat
    17161 aactataatg tttgtgttaa actatttttt ccacagggaa gaaaaaacta tttttaacca
    17221 cgttgtgtat aagtttttat agttcgtttt tttaaacaca tttaccctta tttcaatcca
    17281 tgttatttgg ggatacttat ctctaaaaca taaatagaat aacagacatg tctactggtt
    17341 ttgttttatt cgaggaatta ttcaataata gctagcaaaa tattaaaaat aaccgctcta
    17401 tcttcccatc aatttatttt gcattcaaaa aatgatctat ctttactttt gttgattgac
    17461 ttctcttgga agatgatcgt tccgatacct taattggata cgaaccgatg ttgttaagat
    17521 cctttcccac ttttcttcta gttagacaaa ttattttaga caaaccaaaa aagaggttgt
    17581 gacaataatt tgtcacaacc tcttttttaa aatatctatt ttgtttgatt gttcattgcg
    17641 tcttctgcag ccatttgcgc ttcaatatct gaaatactgt agacattttc gcttgctaca
    17701 ccgacttctt ttggttccat gtcacgataa cgttgcatac cagtaccagc tgggatgatc
    17761 ttacctataa taacattttc tttcaaacca agaagaggat ctttcttacc gcggatcgca
    17821 gcatccgtca agacacgagt tgtttcttgg aatgatgcag cagataagaa actatttgtt
    17881 tctaatgatg cttttgtgat acctagtaag acaggtcgag aagttgcagg aacgcctcct
    17941 gagactagcg tattgtagtt ttgatcttta aagtctgcga tgtctaataa tgtacctggt
    18001 aagatatctg tatcacctgg atccattaca cgaactttac gcagcatttg acgaaccatt
    18061 acttcgatat gcttgtcgcc gatttctacc ccttgcatac ggtaaacacg ttgtacttca
    18121 cgaagcaagt agttttcaac agataataca tcgcgaactt gcaacaattg ttttggatcg
    18181 attgatcctt ctgtcaatgg tgcaccacgg tggatcatat cgccttctgc tactttcata
    18241 cgtgctgtat aaggaacagt atacgtacgt gtatctgttt ttcctttgat tgttacttct
    18301 ttggtacgtg ttgcaggatc ttctgagata tcgatgacat cccctgttac ttctgtgatc
    18361 actgcttgcc ctttcggatt acgtgcttca aagatttctt ggacacgagg aagaccttga
    18421 gtgatatcgt ctccggcaac cccacctgta tggaatgtac gcatcgtcaa ctgagtacca
    18481 ggttcaccga ttgattgagc ggcgatcgta ccaactgctt ctccgacttc aacgtcagag
    18541 ccagttgcaa ggttgcgtcc gtaacaatgt ttgcagacac catgttttgt attacatgtg
    18601 aagacagaac ggattgtcac tgtttcgaca cctgcatcaa cgatttgttt tgcgatgtct
    18661 tcggaaatca attggtttcc tgcaatgatc aattcatttg tttcaggatg acgtacttct
    18721 ttacgggtgt aacgtcccac taaacgatct tctaatgatt cgatgatttc atttccctcg
    18781 cggatggctt ggatttcaag acctcggtca gtaccgcaat cttcttcacg gatgattaca
    18841 tcttgggcca cgtcaaccag acgacgagtc aagtaacctg aatcggcagt cttcaaggct
    18901 gtatcggtca tccctttacg agccccgtga gttgagataa acatttccaa gacggatagt
    18961 ccttcacgga agttcgaaat gattggcaat tccatgattc gaccattagg agcggccatc
    19021 aaaccacgca ttccggcaag ctgtgtaaag ttggaaatgt taccacgagc tccagaatca
    19081 gacatcatga agattggatt tttcgcttcc aaaccttcca tcagtttttg ttggatgctg
    19141 tcttttgcag cattccaaac agcaatgaca cgttcataac gttcgtcatc tgtgatcaga
    19201 ccacgacgga attgttttgt aatagtttca acttgtttat gggcattttc aatgatttct
    19261 tgtttttcat tcagtacact gatgtcagcg atccctactg tgataccggc atgtgtcgaa
    19321 tgtttgtacc ctaagtcttt catacggtca agcatcttag aagtttctgt tactttgaat
    19381 cgtttgaaga cttctgcgat gatgtttcct aagtttttct tcttgaacgg taatactaat
    19441 tcttgctctt tgatatgtgc aggaatatca gtaccagctt caacaaagta tttgtccggt
    19501 gtttggacgg tcaagttgaa gtctgttggt tcattcagat aagggaattc aggaggcatg
    19561 atctcgttga agatgatctt accaactgtt gtgatcatcg tacgttcttt ttgccattca
    19621 gtaaatggtt tttcacctaa tgagttaggg ttcacaccga tacgtgaatg taaatgaaca
    19681 tatccgttgc gccatgcgat aacggcttcg ttttgatctc tgaagaccat tccttcgcct
    19741 tcgcgtcctt cttcttccat tgtcaagtag tagttaccta gaaccatatc ttgagaagga
    19801 gtaacaactg gtttaccatc tttagggttc aagatgtttt gagcagctaa catcaacata
    19861 cgtgcttctg cttgtgcttc ttcattcaat ggaacgtgga cagccatttg gtctccatcg
    19921 aaatcggcat tataagcttc acatacaagt ggatgcaaac ggattgcgcg tccttgtact
    19981 aaaactggtt cgaatgcttg gataccaagt cggtgaagcg taggtgcccg gttcagcaat
    20041 actgggtgtt ccttgattac gtcttctaaa acatcccata cttcgtcttc ttgacgttcg
    20101 attttacgtt tcgcattttt gatgtttgaa gctagttcgc gttgaacaag ctcacgcatc
    20161 acgaatggtt tgaataattc aatggccatt tcttttggaa gtccacattg gtacatcttc
    20221 aagaaaggtc caacaacgat aacggaacga cctgagtagt cgacacgttt acctagcaag
    20281 ttttgacgga aacgaccttg tttccctttc aacatatgag aaagagattt caatgggcgg
    20341 ttacctggtc cagtaactgg acgtccgcga cgaccgttat cgatcaatgc atctactgct
    20401 tcttgcagca tacgtttttc attttgaacg atgattccag gtgcattcaa gtctaacaaa
    20461 cgtttcaaac ggttattacg gttgattaca cgacggtaaa gatcattcaa gtcacttgtt
    20521 gcaaaacgtc caccttctaa ttgaaccatt gggcgtaaat ctggtggaat aacagggata
    20581 acgtccataa ccatccagct tggttgattt cctgaagcgc ggaatgcttc taaaatatcc
    20641 aaacggcgga ttgcacgtgt acgtttttgt ccttgtgcag atttcaattc ttctttcaat
    20701 tcggctgctt ctgcatctag atcaacatta tcaagtaatt gtttaatcgc ttctgcaccc
    20761 atagcagctt ggaattcttg tccatattgt tcacgttttt cgcgatattc gcgttctgtc
    20821 aacaattgtt ttttctctaa attcgtattt cctggttcga tgactacata tgaagcaaaa
    20881 taaatgattt cttccaaagc gcgtgggctc atgtctaata caagacccat acgtgaagga
    20941 atccctttaa agtaccagat atgtgaaaca ggagctgcta attcaatatg tcccatgcgt
    21001 tcacggcgaa ctttcgaacg agtaacttcc actccgcatc gatcacaaac gattccttta
    21061 taacggatac gtttgtattt tccgcaggca cattcccagt cttttgtagg accaaaaatc
    21121 cgctcacaga acaacccttc gcgttcaggt tttaaggtac gatagttaat cgtctcaggt
    21181 ttttttactt caccgtaaga ccagcttctg attttttcgg gagaagccaa acctatttgc
    21241 atactttcga atttatttac atcgatcaaa aggggttccc tccatttcat ttaatggcaa
    21301 accgcaagac ggctgatctt cgaccgcctt gcagctcata gaccggatta gtctaaatta
    21361 tcttctgcgg tttcaaagtt ttggatgaca tcgtcttttt catcttccac ttgttcagca
    21421 gctttctttt ctaattcttt ggcagtttgc tgttcggcaa attttgtcaa agcatcaaca
    21481 gtgatcaaat cgtcgtcttc atcgtccatg tcgcgaagtt cgatctctgt ttcttcgata
    21541 tccaagacac gcatgtccag acctagtgat tgcaattctt tcaccaatac gcggaatgat
    21601 tccggtacac ctggttttgg aattggttca cccttgacga ttgcttcgta tgttttcaca
    21661 cgtccgacta cgtcatctga tttgtatgtc aagatttctt gtaaagtata agccgcaccg
    21721 taagcttcca gtgcccatac ttccatttca ccaaaacgtt gtccaccaaa ttgagcttta
    21781 cctcccaatg gttgttgtgt aaccaatgag taaggtccga ttgaacgtgc atgcaatttg
    21841 tcatcgacca tgtgagcaag tttgatcatg tacatcacac cgacagacac acgtccatca
    21901 aatggttcac ctgtacgtcc gtcgtacaga acagttttcg catcgctggc cataccggct
    21961 tcacgaactg tttcccatac gtcttcatca cttgcaccat caaatactgg cgttgctacg
    22021 tggataccta actgacgtgc agccataccc aagtgtaatt ccaatacttg cccgatgttc
    22081 atacgtgaag gcacccctaa aggattcagc atgatatcga ttggtgttcc atcaggtagg
    22141 aatggcatat cttcttccgg cataatacgg gatacaaccc ctttatttcc gtgacgaccg
    22201 gccattttat ccccttcatg gattttacgt ttttgaacga tataaacacg aactaacatg
    22261 tttacgcctg gtgacaattc atctccagct tcacgagtaa agattttcac atcgtgaacg
    22321 ataccgccgc cgccatgtgg tacacgtaat gatgtatcgc ggacttcacg agctttttcg
    22381 ccaaagatcg catgcaatag acgttcttct gcagataatt ctgttacccc ttttggcgtg
    22441 actttcccta caagcaaatc gccatcttgg acttctgcac caatacggat gatacccatt
    22501 tcgtctaaat cttttaatgc gtcttccccg acattaggga tttcgcgtgt gatttcttca
    22561 ggtcctaatt ttgtatcgcg ggcttctgat tcatattctt caatatggat agaagtgtat
    22621 acgtcatctt ttaccaaacg acggctcatg atgatcgcat cttcatagtt gtacccttcc
    22681 caagtcatga aaccaactaa aacgttttgg cctagagcca tttcgccttg ttccatagat
    22741 ggtccgtctg ccagagtatc ccctttttcg actttctcac ccaaatgaac gattggacgt
    22801 tggttgtagc ttgttccgga gtttgaacga cggaattttg ttacatcgta tttatctaat
    22861 gcaccgttgt cgcggcgtac gcggatttca gaagcatcaa cgtattcaac gacaccgtca
    22921 tgtttacata acaaagcagc tcctgagtca tgcgctgatt tgtattccat accagtacca
    22981 acccatggtg cttgaggatt gatcaacggc actgcttgac gctgcatgtt ggcacccatc
    23041 aaggcacggt tggagtcatc gttttccaag aaaggaatac atgctgtcgc aacggcaact
    23101 acttgtttag gtgatacgtc catgtagtct actttatcaa tagatacttc taagttttca
    23161 ctttgagcac gagccataac aacgtcttga gcaaatgttc catcttcatt caatgggctg
    23221 tttgcttggg ctacgatgta atggtcttcg atatcagctg tcaagtagtc gatttggtca
    23281 gtaacacgac ctgtttcacg gtctacacga cgataaggtg tttcgataaa tccgaattta
    23341 tttactttcg cataactgga caaactattg atcaacccga tgtttgggcc ttcaggagtt
    23401 tcgatcggac acatacggcc atagtgggag tagtgaacgt cacgaacttc ataaccggcg
    23461 cggtcacgag tcaatccgcc aggtcctaag gctgaaagac gacgtttgtg tgtcaattcg
    23521 ccaagagggt ttgtttgatc catgaactgt gacaactgag aagaaccaaa gaattctttg
    23581 atacttgcca caactggacg gatattgatc aattgttgag gtgtcaatgt ttcagtatct
    23641 tggatcgaca ttctttcacg aaccacacgt tccatacgtg ctagcccgat acggaattgg
    23701 ttttgtaaaa gttcaccgac tgaacggata cgacgatttc ctaagtggtc gatatcatcg
    23761 acattgccga taccttccat caagttcaag aaatagctca ttgaagcaat gatgtcggct
    23821 ggacgaaccg tttttacagc tgcttctgga tagccgtttc cgatcacgtt tacttcacgt
    23881 tcagggtctc ttggtgaaaa tactttgatg acttggacag tcattggatc tgtgaccaca
    23941 ccgtcttctg atggatagta agtcactgaa tttaggccat tatcaatgaa aggagctagt
    24001 gtttccatga cttggtgagt cagaactgtt cctttttcaa cgatgatctc gcctgtttct
    24061 ggatcaacta atgtttcagc taatgtcaga ttcaatagac gtgttttcaa atctaatttt
    24121 ttgtttactt tgtaacgacc aacgtttgct aagtcgtaac gttttggatc gaagaaacga
    24181 gcattcagca agttacgtga gctgtctgct gtttttggtt cgcctggacg caaacgttcg
    24241 taaacgtctt tcaaaccttc ttctgttctt gagtcgcttg cgtttttatg caagtctttt
    24301 tcgactgtat tgcgtaatgt ttcgctgtcg ccgaagattt caaagatcgt atcatcggaa
    24361 ccaaatccta acgcacgaac taatacggtt aaaggaatct tacgtgtacg gtcgatacgt
    24421 acataagaga tgtcttttgc atcagtttcc atttctagcc aagctccacg gttagggata
    24481 acagtagaac cgaatccttc ttttccgttt ttgtcgactt ttccatggaa atagacacct
    24541 ggtgaacgga ctaactgaga aacgattact cgctctgccc cgttgatgat gaatgttcct
    24601 tgttctgtca ttaatgggaa atcaccgaag aatacttctt gtgctttgat ttcgccagtc
    24661 tcgcggtttg tcaaacgcaa tgttacatgt aatggtgcag agtagtttgc atcatgcgca
    24721 cgagcttctg ctactgtata ctttggttct ttcaattcat aatctacaaa ttccaaagat
    24781 agattgccat tgaagtcatc gattggcaaa atgtcttcaa acatttctct aagtccctca
    24841 tctaagaacc attggtaaga gtctgtttga atttcgatca aatttggtaa ttccaacact
    24901 tcactgattc ttgcgaaact tctacgttcg cgatgttttc cgtattttac tacgtgtcca
    24961 gccaagctct tcacccctct aaaatgtcat tcaaaaagac tacccgatca attgttacaa
    25021 taatatttca aatattattt ttaggtaaca acagacattt tttgcggctt ttaggcaaaa
    25081 aaaaaccaaa aatagaacat tctcttgaaa ccttacttcg tgagcttcta cttttgtttc
    25141 cttatattaa agccgaaacg gacaatattt cgtttctgcc ttttcttcat cagatagttt
    25201 ttgcaacttc atatactaca cttattttct ataaaagtca acacttcctg gcgtttcttc
    25261 tgctttttcg caacattttc ttaatgtttt caattttatg ttttcaatta tctgacaatt
    25321 cttaattgac agaccttttt atctcggtta tactttagaa aattcatttt gtggaggaac
    25381 ttctatgcga accaacatca accaaatcgc accaacacaa ctgaataact tttactttag
    25441 ctactttaga taggtttgta ttcatcatga tggatacaaa cgttaaacga cagtttgtat
    25501 ctatgatggc taaagaactt tgtattgcag caaaaagcca cgtagacaaa atgctaagtg
    25561 gctgagcagt gaaaatacaa agtaaaagta tcaagcattc tactttttca atttattttc
    25621 cgacttttca atccatttgg acattttgtc tgaatggatt ttttgtttcc caaaattaag
    25681 gaggaaaaag aaatgaaaaa aaatataatc atcggattag gcgctgccct gctactagct
    25741 ttaggaggtt gcgcacaaaa agacaattcc gcagaggcat cagatggaca aaaaacaatt
    25801 ggcgtattgc aacttgtaca acataactcg ttagatgctg cctataaagg attcaaagaa
    25861 ggattagcag aagaagggta taaagaaggc gataatctaa caatcgatta tcaaaatgcc
    25921 caaaacaatc aagacaacct gaaaagtatg agtgagaaac tcgtcaaaga agatcctgat
    25981 ttgctacttg gaatcgccac tccagcagca caatctttat taaatgaaac aaccactatc
    26041 ccgatgactg tcacagcggt cacagacttg gaacaagccc atttagtcac atccaatgaa
    26101 aaacctggcg gcaatgtgac tggcacgaca gatatggtgc caatcgaaaa acaaatcggc
    26161 ttactgttaa atatcgtgcc agacgccaaa acaatcggca tcatgtataa caacggtgaa
    26221 gcaaactcta agatccaagc tgatttggca gaaaaagaat tgaaaaaagc gggcgtcaaa
    26281 gtcaaagtac tgacagcaaa ttccacaaat gatgtccaac aagtgacgaa aagtctagct
    26341 aaagatgtag atggaatcta tattcctact gataacacgt tcgcaagtgc ggcaagtgtt
    26401 gtcggtgaag tcgcaaaaga aacaaaaaca cctgtcgttg ctggcgcagt tgatcaagtc
    26461 aaagacggcg gtctagcaac agtaggaatc gactacgaaa gcttgggcaa acaaacaggg
    26521 atcatggcag caaaaatctt agacggcaag aatccaagtg aacttcctgt cgaaacagcg
    26581 aatgatttgg aactgtatgt caataaagac atggccaaag cattaggcat caatccagac
    26641 agcatcaaag aagctgaata aaacacagga ggattctcat gacaaatttg ctctctcttt
    26701 tcttatcatc tgcatcgcaa ggggtcttat gggccctact tgcgattggt gtatacgtca
    26761 ctttccgtat cttggacatt gccgacttga ctgctgaagg aagctttcct ttaggtgcag
    26821 ggatcgcggc agtaagtatt acaaatggct atcatccatt gacagcttgt cttctaggct
    26881 ttttaggggg tgcggcagca gggcttgttt ccggactgct tcacacaaaa ttgaaaattc
    26941 ccgcccttct tgcagggatc atcaccatga ctggtttata ttctgtcaca tcccgtgtga
    27001 tgggtgcgcc gaacatctct ttattgggtc agccaacgat ctttcattgg gtcgagtcat
    27061 tcggcataac aaaagacaac gctgtactga tcgtcggtct gctttttgct ttgatcgttg
    27121 tatgtttact tgttttgttc ttacgtacag aaacaggact tgctattcgt gcaactggcg
    27181 ataatctggc aatgagcgaa gcaaacggga tcaacacaga taatatgaag atcatcggtt
    27241 atatgatttc taatggatgc attgctcttt ctggctcctt acttgcgcaa aacaacggct
    27301 ttgctgattt aaattctggt attggaacga tcgtaattgg acttgcttct attatcatcg
    27361 cagaagtttt gttacgtaac cagccactat ttctccgtct cttgactgtc gttttaggtg
    27421 cggtcattta tcgttttatt ttagcgttag tcttcgaact gaatgttgaa ccaagtgatt
    27481 cgaaacttgc ttctgctttc gtgctagtga tctgtctttc tttcccgcag atccagcaaa
    27541 aattccattt acctcaaaaa aagaaaggcg gtagtgtcaa atgaatgacg tcttaacatt
    27601 ggaaaatctc catcatacct ttgaaaaagg aacgatcaac gaaaatcatg tcctgaaagg
    27661 cattaatctt tccttagatc ccggcgactt cgtgacgatc atcggtggaa atggggctgg
    27721 taaatctact ttgctgaaca gcatcgccgg tacattttct gtcgatcagg gtcaaatttt
    27781 attgaatgga aaaaatatca cgaaaaaatc tgttgtcgaa cgttcgaaat ccatcagtcg
    27841 cgtattccaa gatcctaaac tagggacagc cgttcgttta acggtagaag aaaatcttgc
    27901 tcttgctatg aaacgaggaa aaaaacgcgg cttcttccgt ggtgtcaaac cacaagaccg
    27961 aacatttttc aaagaccagc tggttcggct aaatttgggg ttggaaaatc gtttatcctc
    28021 agaaatcggt ttgctgtctg gaggacaacg tcaagctatt acgttattga tggccacatt
    28081 acagcgtcca gaactgatct tattagatga acacactgca gcgcttgacc ctgctacttc
    28141 caaaacggtg atggaattga cagaaaagct gatcactgag cagaatctca ctgcttttat
    28201 ggtcactcat gacatggaag acgcgatccg ctatgggagt cgactgatca tgctgcatca
    28261 aggaaggatc gtcgtagata tccagcaaga ggaaaaacag cagctcacag tgccccaatt
    28321 attagcgttg ttcaaacaaa acagcggcac ggcattaaaa gacgatcaag tacttttatc
    28381 ttcataatca gaaagaggat gggacaaaaa atgaacgccc accctcttct tttttctctt
    28441 tccttctttc gtttttgctt tatgtatcaa ccgttgtttc ttcgaaaact attttgttct
    28501 ctccttcttc ctgatagaat ggatgggaaa ggagcttgat gccatgacaa cgaaagacaa
    28561 ggtacttcaa ttattgaaaa agacaccaga ttttctttcc ggagaaaagt tggcacagca
    28621 actggaagtt tcccggacaa gtatttggaa agccatcaaa gaattggaaa aggcaggcta
    28681 tcgttttgag cacgggccta cagggtatcg ttacctgccc tctgacgtac tagatgcaaa
    28741 agaaatccag caagagctac ggtcgtttat tcctgatttg aaagtacaaa cgatgttgac
    28801 ttctgaatct acgatgaaag atgccaaact ggcagcagct caaggagatt ctgtttcgaa
    28861 gttatttgtt gctgatacac aagaacaagc tcgtggacgt tttggacggc cttttttcgc
    28921 tgaacctgga cgaggaatct acatgagtct cttgctccat ccagacaaac ggtttgatga
    28981 attgcctcaa tatacgatca tcgcagccag tgcctgtgtg aaagccattg aatctgtaac
    29041 cggtcgttct gcttcgatca aatgggtcaa tgatatctac atggatggaa aaaaagtctg
    29101 tgggatttta tctgaagcag tcagtgatat ggaaagcggc aggatcagtc atatcatcat
    29161 tgggatcggg cttaattttt ctgttcctca aaatcatttt ccagctgatc tccaagaaaa
    29221 agccatctct gtctttcccg acggacaagc tagtgtcaca aggaatcagc taatcagcaa
    29281 aatctggcaa gaattgttca cttatctttc tcacccagaa aaagcgttgg acttctataa
    29341 agaaaaatca ttcgtattgg gaaaaaccgt gtcgttcaat caaaaaggaa cgacttatgt
    29401 cggtcttgca aaagaaatcg gtgatcatgg cgaactgatc gtccaaacaa atgaacagaa
    29461 gatgagtttg tcttctggcg aaatcagtct cacatctatc cgtacgcaat aattatcaga
    29521 tttcacaaaa ggacacctga tctcatacag tgtccttttt tctgaattct cttcaaaaga
    29581 ctctccttat tctatcagct gacagtttct ctatcctcta gaaaaaggta ttctaaaaat
    29641 atctataaag catggtacac tttctttaaa tgaatcaatg caaaaaacaa gagagtcatc
    29701 agtttacacg atcaaaagag atagcaggcc gcttcctttt tcaatcttat agatagacca
    29761 tgggtaacga taaaaacaaa aaagaacttg cgacttattt tgccgtaagt tcttttttag
    29821 ctagtgcctt aatctcttaa tcccaacaaa cgtctcgcat agatcacctg accagagtgc
    29881 atagcagcat catcaataat agaaacgaga cgcattcctc gtgtgactgg tggtgtccag
    29941 ttctcgtcaa ttacttcatc tagctcggaa ggttccagcc ttcttaagta agaaatagca
    30001 aaatcagcag ctcctcgcaa gtatcctagc agatcttcta tttgattagc ttggatctgc
    30061 tttgcttgtt ccagactatg cttccaatct tgttcgttat ctgctatcgt catcggaaac
    30121 cggctttccc agtcttgact atgccaaatt ggagaagttc ctgctaaatc agcaatctgg
    30181 aaatctaatt ctcgagcggt atgccaagcc agccaagtca ttgatttgat ctgcggggct
    30241 ctatcttcca ctggaaaacg attggcctcc tcaatagaga cgccttcaaa caaacgttca
    30301 aaccgatcgt atgcccgatc cacactctcg catagcatat ctaaataatc catttatttt
    30361 cctccttttt atttatccta cttacttttt cctaattcta ggatacctac ttatatgtta
    30421 ctacacaccc ttatttttta cactttaaca gtcaccatca tcaatagttt ggagattgaa
    30481 agaaaaagat agtgtcgaac tatcaattga acaagaagca acaatatgaa cgtttcatta
    30541 atattcttta aataaacaat gatttttcaa acgaacagtt taagactagg agaaaaagag
    30601 tataatagga aaatgtttga aaggaaagga aggggaaaaa tgaaaaaaag ggcaagttta
    30661 ctagtcctag ttgctttgtt gttcaatatc ttttcgtatg gtgtggccgt ttcagcggaa
    30721 acatacattc ctaaagaccc tgggaatatt tataatgatc taactggtaa ctatggcttg
    30781 ttaggaattg ctagtcaatt ccacgtattt gctaaaaata agacaactgt gaatgcacat
    30841 acagacggaa atatagcaac acatgaactt gatgcaaaaa ataattttgg tacagagctt
    30901 catgaaggtt tattgaacca agaaataaat tatatacaaa aaactgattc tttcgctaat
    30961 tcttcaggca tacctacagg tagcacaaga atgaataaat ttgtcgttgg cagtaacgtg
    31021 gatgtagcac ttcaagatgg tcatcctaca gtcaatggat ccaggcttga tcacttaact
    31081 ccagatgatt tttataaaga tcgtgctggg catgaatata ttgatttcga gcaggaattt
    31141 gctaaattga atgtagcagc aaatgatctt gcaacgatca ctccagctaa aacatatact
    31201 gctgcagatt ttccagacat gaacaatcgg acaatcgatt taactgattt atcagatacc
    31261 gggtttttat tggtaaatat cgatgcagaa gtgttaacga tgaatacgcc acttcaaatc
    31321 attaatccaa atgatcaagt agttgtattt aatgtcatca acagttcttc tgcattgaac
    31381 gtacagtcac caatcaaata caatgatcgt tcaaatcatg aaacagaaga tttttcggat
    31441 gcgaatatct cttggaattt tggaaatgag atgactgatt tgacaatcag tgctcctttt
    31501 caaggaacaa tccttgcgcc taatgctact atccgcatta ctcaaaacca agacggaacg
    31561 attataggaa caaatgtgat tttagatgca gctaccaatc gttgggatcc taacgaaata
    31621 tttatcagcg acaatggtac agatacgaca gacacaagcg acagtacaga tacatctacc
    31681 acaagtgata gctcagattc atcaacttca agcgacagta cagatactac ctctaccaca
    31741 ggatacatca gcttcaagcg acagtacaga tactacctct accacaagtg atagcacgga
    31801 cacatcagct tcaagtgaca gtacagatac tacctctacc acaagtgaca gcacggacac
    31861 gtcagcttca ag
//
LOCUS       DAIGUC010000033        31334 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.033, whole genome shotgun sequence.
ACCESSION   DAIGUC010000033 DAIGUC010000000
VERSION     DAIGUC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.033"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            1..369
                     /locus_tag="NOB46_001620"
     CDS             1..369
                     /locus_tag="NOB46_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCI1058555.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="NOB46_001621"
     CDS             549..1490
                     /locus_tag="NOB46_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCI1058556.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="NOB46_001622"
     CDS             1559..2290
                     /locus_tag="NOB46_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HCI1058557.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="NOB46_001623"
     CDS             2434..4614
                     /locus_tag="NOB46_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCI1058558.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="NOB46_001624"
     CDS             4634..5116
                     /locus_tag="NOB46_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HCI1058559.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="NOB46_001625"
     CDS             5132..5893
                     /locus_tag="NOB46_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI1058560.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /locus_tag="NOB46_001626"
     CDS             6024..7358
                     /locus_tag="NOB46_001626"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCI1058561.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="NOB46_001627"
     CDS             7665..8150
                     /locus_tag="NOB46_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HCI1058562.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="NOB46_001628"
     CDS             8143..8826
                     /locus_tag="NOB46_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCI1058563.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="NOB46_001629"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="NOB46_001629"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCI1058564.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="NOB46_001630"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="NOB46_001630"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HCI1058565.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /locus_tag="NOB46_001631"
     CDS             12442..13071
                     /locus_tag="NOB46_001631"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCI1058566.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="NOB46_001632"
     CDS             13123..13455
                     /locus_tag="NOB46_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI1058567.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="NOB46_001633"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="NOB46_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCI1058568.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="NOB46_001634"
     CDS             14281..15654
                     /locus_tag="NOB46_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI1058569.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="NOB46_001635"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="NOB46_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HCI1058570.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="NOB46_001636"
     CDS             16709..17149
                     /locus_tag="NOB46_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCI1058571.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17293..17994
                     /locus_tag="NOB46_001637"
     CDS             17293..17994
                     /locus_tag="NOB46_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HCI1058572.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17991..19112
                     /locus_tag="NOB46_001638"
     CDS             17991..19112
                     /locus_tag="NOB46_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCI1058573.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19127..20359
                     /gene="pepT"
                     /locus_tag="NOB46_001639"
     CDS             19127..20359
                     /gene="pepT"
                     /locus_tag="NOB46_001639"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCI1058574.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20491..21399
                     /locus_tag="NOB46_001640"
     CDS             20491..21399
                     /locus_tag="NOB46_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCI1058575.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21434..21706
                     /locus_tag="NOB46_001641"
     CDS             21434..21706
                     /locus_tag="NOB46_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCI1058576.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21717..22763
                     /locus_tag="NOB46_001642"
     CDS             21717..22763
                     /locus_tag="NOB46_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCI1058577.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23014..25623
                     /gene="clpB"
                     /locus_tag="NOB46_001643"
     CDS             23014..25623
                     /gene="clpB"
                     /locus_tag="NOB46_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCI1058578.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25774..26460)
                     /locus_tag="NOB46_001644"
     CDS             complement(25774..26460)
                     /locus_tag="NOB46_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058579.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26438..26932)
                     /locus_tag="NOB46_001645"
     CDS             complement(26438..26932)
                     /locus_tag="NOB46_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI1058580.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26952..28172)
                     /locus_tag="NOB46_001646"
     CDS             complement(26952..28172)
                     /locus_tag="NOB46_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058581.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28319..30154
                     /gene="lepA"
                     /locus_tag="NOB46_001647"
     CDS             28319..30154
                     /gene="lepA"
                     /locus_tag="NOB46_001647"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCI1058582.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(30248..>31334)
                     /locus_tag="NOB46_001648"
     CDS             complement(30248..>31334)
                     /locus_tag="NOB46_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1058583.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        10431 a         5601 c         6715 g         8587 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggtagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aacattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 aaacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaatttt tttattccta gtctccttat tttatttgga aaatgctata attatctaga
    17281 aggagtgaag ctatgaacca tttagattta tctcagcgct tagccgcagt gggtgacttt
    17341 gtccctgaat ccgctcgttt agcagacatt ggatcagatc acgcttactt acccgttgca
    17401 ttgatattaa gaggaaaaat cgaatatgca gttgctggtg aagtcgttca aggtccttat
    17461 gaatcagcac gtaagcaagt caaaaaagat ggattagaag accgtatcac cgtacgcctt
    17521 gcaaatggtc tagatgctat ccagccacaa gatggtatta cagctgtcac gattgcgggt
    17581 atgggaggtt cactgatccg agatatccta gaagctggca agttgaatca acgcttaagc
    17641 ggacaagaac gtttgatcct tcagccaaac atcggagagc gtacattacg atcttggctg
    17701 caagaaaatc agtataaaat ccaatcagaa aaaatacttg aagaaaataa aaaaatatat
    17761 gaaatcattg tagccgaaaa agaacaaaaa ccagttactt acaatgaaat ggagctgatg
    17821 ttcgggccat ttctgcttga agagaaaagt gagatcttca aatcaaaatg gacaagagag
    17881 cttcaacaaa gaaaagctat ccgtgaacag ctcaaacaag cagctaatca agaggcacgt
    17941 caaaaacaaa tcgagcagga aatccaaatg attgaggagg ttttaaagcc atgacaatca
    18001 gcggacgcac tttcatccaa aagtttgaaa gctattgtcc tcagtggcta gctgaagaag
    18061 gagacccagt cggactgcat atcggaacat tggataagcc aatccaacga gtaatgatga
    18121 cattagacgt tcgtccagaa gtggtcgaag aagcaatcaa gaaaaaaatc gatttgctga
    18181 ttgctaaaca tcctccaatc tttcgtcctg taaaacggct ggttactgat cagccacaag
    18241 aaaaaatgta tgcagatttg ttgaaacatg atattgccgt ctatgcagca cacacgaaca
    18301 tggatattat ttgggatgga ctgaatgact ggttttgtga acttctcggt attgaagtgg
    18361 agagttattt agtaaagact catgagattc attataaaaa actggccgtt tatgtacctg
    18421 tggatcatgc acagaaaatg cgtgaagtat tagctgcagc tggtgctggt acacaaggtg
    18481 attataccgg tacaagtttt acctcgattg gacacggtcg atttactccg gaagctggtg
    18541 cacaaccagc gattgggaaa gtagggaaga cagaacaagt tcaagaggca aaagttgagg
    18601 ttattttgcc ggaaactatc gaaaaacaag tgattcaagc catgcggtca gctcatcctt
    18661 atgaggaacc tgcttatgat cttttcgcta tagatgaacc agtcgaaatg tttgggttag
    18721 gacgagtagg tgaattgccg caagaaattt ctatagaggc atttgtagaa caagtaaaag
    18781 aagcgttcca actagatgga ctgagaatag tccagccaaa aaatgcaaaa tcctctgtga
    18841 agcgcattgc gatttgcggt ggaagcggtg aaaaatttta tccgcaagca atcgcccaaa
    18901 gagcagatgt ctatatcacg ggagatatct attatcatac ggctcatgat atgcaaagcg
    18961 ctgggttgat tgcaattgat cccggtcatt atattgaatc gttatgcaag caacgattta
    19021 tcgagaaatt tgaatcttgg aaacaagaag aaaattggga tattaacttt ttcgtttctg
    19081 aaacaaatac aaacccattt caatttaatt aaaaggagag aatactatgt acgaaaatct
    19141 tttgccacgt tttttacgat atgtcaaaac agaaacacgc tccgatgcaa caagcaaaac
    19201 gactccatcg actcagacac aagttgcttt tgcgcaagaa ttgaaaaaag aattagaaga
    19261 gttaggctta gctgatgttt tctataatga agataacgga ttcgttatgg gaacattacc
    19321 aagcaatgtt gatcatgaag tgcgttccat tggatttatt tcccacatgg atacagcaga
    19381 ttttaatgca gtaggagtca atccacaaat cattgaaaac tatgatggcg agtctacgat
    19441 cgtactagat gcggaagaac gctatacatt gaatacaaaa gattttccaa atttgaaaaa
    19501 ttatgaaggc cacacattga tcacaacaga tggcagtaca ttactgggag cagatgacaa
    19561 atcagggatt gcggaaatca tgactgcaat ggagatcttg atcaataatc cttctatccc
    19621 tcacggtacc atcaaagtgg cttttggtcc tgatgaagaa atcggtgtcg gagcggataa
    19681 attcgatgtt gagcaattcg atgtagattt tgcttataca gtcgatggtg gtcctttagg
    19741 tgagttgcag tatgaaacgt ttagtgctgc tcaagcaaat attacgatcc aagggaaaaa
    19801 tgtacatcca gggacggcaa aagatacaat gatcaatgct ctacagttag caatcgattt
    19861 tcataatcag cttccagccg atgaagttcc agaaaaaacg gaaggatacg aaggtttctt
    19921 ccatttgatg gcattggatg ggaatcctga agaagcttct atgagttata tcattcgcga
    19981 tcatgatcgt gaaaaattcg aagcacgcaa agcacaaatc acacatatcc aagaagagtt
    20041 gaatcagcga tttgatcaag aacgaatcaa agtagatatg tatgatcaat attacaacat
    20101 gaaagaaatc attgaaaaag atatgagcat cgtggaatta gcgaaacaag caatgatcga
    20161 gcttggtatc tctccagtga tcgaaccagt tcgtggagga acagatggtt caaaaatctc
    20221 ttacatgggt attccgacgc caaatctatt tgccggagga gaaaatatgc acggacgatt
    20281 cgaatttgtt tctttacaag taatggaaaa agcaacagac gtgattgtaa aaattgcaga
    20341 attgaacaca aagagttaaa atcgaaaaag aacagcttat gacaaggcgt tcgtcccaat
    20401 gatggaatgt catctgtcta aggctaaagg gcaggacaat ggaattggtt gtcccgccct
    20461 cttttttgaa gagtaaatag gaggtaaaga atggaaaagc tgctagtttt ttataacaaa
    20521 agttcaggga aagatgaggg tgagaaatta gcacgctggt ttcaagatta tgtaaaagaa
    20581 aagcagccag aattatatgt agaactagct gaaactggcc catcgattga tgatgcggaa
    20641 ttagtcaaga aagcagaagc catagaagct gatactttag taattatagg tggagacggc
    20701 acgattcatc atatcgtcca agcgttccaa aaaacattat ctcaatacca tgtcggatta
    20761 cttccaggtg gaactgtcaa caaccttgca cgtgttcttg agattcccct caaaaaagaa
    20821 gaagctgctg acgtgatcct ggaaggcaat gtacggaaaa tagactatgg tcaagtcaat
    20881 gatgaagtca ttatctctac actgacaatc ggaatcttag cagatacagc agtttggatc
    20941 agtcaagaag aaaaacagcg ttacggctcg tggatcttta tcaagaagtt ttttaagtta
    21001 ttgctgaaga agaaaaaata tcatttggat ttagaaacag acgaggagca ttggaaagga
    21061 aaatcccaac tgttgacagt cacgatgtct aactccgtgg gcggttttac aaattttgac
    21121 gactcagcga ccctagatga tggaaaattt catgtaacga tcgtaccttc cttagatatt
    21181 ttccgattta ttttttattt gcctagaatc atgagaggca aattctatac gatccccggc
    21241 attacttatt tcacagccaa acgcatgaaa atccaagcgc aggaaaaatc tgtgggcact
    21301 cgaacggatg gagacacgac agatgatctt ccagttgaat tatctgttgt atcaaaagga
    21361 ttaacagttt attcaccaaa gaaagaagaa aaagcttaga aatagtagtt aacagaaagt
    21421 tggaagaaga gtaatggatg tattgttaca caatcctttg tggttttacc ttttcattgt
    21481 gaatttttac ttattttgtc tgatggggta tgataaacat caggctagaa ctagcggctg
    21541 gcgtgttcct gagaataatt tgatatttgt cagcctgtta ggcggtggtt tgggaggatt
    21601 gatctctcga aaagttttcc atcataaaac tcggaaaaag aagtttacta taggattcgc
    21661 tgcaggtgta cttgttgatt tgattctcat ttattttttc cattaaggag caggagatgt
    21721 cgtctaaagg aacgaaaact aaaatcattc tgaatctgct tttgctgatt gtgatttttg
    21781 ccattattta ttatttaatc aatcaatcat ttgcagatat ctttgccgaa ttgctgtcta
    21841 ccagtgttgt tgttttggca gcggctgtta tattagggac agtttaccaa atcgctgaag
    21901 ggcgctcaat caaagaaatt gctgaacctt tcgcgccgaa ttttacaacg aaagatgggt
    21961 tcttgacctc tagctatatt gcgttttacc gaatcgtttc gtttggtaca ggaacgctga
    22021 tctcggagat ttatttttat aacaaaaaag gaatgaagct atcccaggga gcaggggtga
    22081 cagcactcca tatgattatg tacaaactgg cagtgatcac ttatgcatta gctggcttgg
    22141 tcatccaatt ctctcttttt tattctaatg gtccatcaat gatctggttt atcatcgctg
    22201 gtatcctttt gacgatcgtg attgttgcct ttttattggc gatgtccgtc agcttgaatg
    22261 ttcaaatatt ttttgtcagc ttatcgaata agttatttaa aagtgagcgt ttgcggaaat
    22321 gggtggatac atgcaatcag cagatctact ctttaaggga aacggtccaa accattatcc
    22381 aagacaggac tgcgctattg cggatttatc tatggaatat gttaaaactt gtattttggt
    22441 atgtacttcc ttatttgatt ctgattgaaa accatcctaa aatagatttt ctactgacca
    22501 tttcgtttat cagctttgca gtagtgcttt caggggttat tcctacgcct gctggtattg
    22561 gttcctttga atttgtctat ttgttattat tcagaccagt tgttggaaca gttgacgcag
    22621 tttcttcgct tttactgtat cgtttcagtt cctttatctt gccatttctc tatggatttg
    22681 tgtatgtgat tgctgaacgg cgaagagtga tcaaagaaga aataatagaa gtaaaaaaag
    22741 agaataaaga aaatcaaggg taggtctttt ataagatcta ccctttttat caaatcaaag
    22801 aaaaacgtta tggataagat aattttacgt ttgtttggct ctttttttat atacatacaa
    22861 tcaattttgt ttttttaaga tttatataag tcgagaaaaa aagtcaaaaa actatgtgta
    22921 tattttgacc aaaattgacc aaagcgatat aatagttttt gtaaagatca aagaaataag
    22981 tgatcttacc tttaattagg agggtatacc tgtatgaata ttgagaaaat gactacgacg
    23041 cttcaagaag cgattgctga agctcaacag attgcggtca ctcgaaaaca tcaagatatc
    23101 gacattgccc atgtatggaa aatcttttta caatctaatc attttggtcg aaatttctat
    23161 acggatgccg gattggatgt cgaatctttt gaacatgaaa ttgatcgtct actggatgag
    23221 tatccagttg tttctggtgg aaacgtccaa tatggacaaa acctcagcca gaatttcttt
    23281 cgattattga atgaagcaga ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg
    23341 gaagtcgtta ttttagcgtt gatgaaatta aaaaattatc cgttaactgt ttatttgaat
    23401 aaaaacggat tatctgaaaa agaattgcgt aaaaacatcg aagagatgag aggaggagaa
    23461 agagtgacct cacaaaacca agaagaacaa tacaaagcat tagaaaaata cggcgttgat
    23521 ttagtacagc aagtcaaaag cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc
    23581 cgtgatgtca tccgtattct ttcacgaaaa acaaaaaata atcctgttct gataggagaa
    23641 cccggtgtag ggaaaacggc aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat
    23701 gtgcctgaaa atttaaaaga taaaacgatt ttttcattag atatgggtgc attgatcgct
    23761 ggagcaaaat tccgtggtga atttgaagaa agactaaaag cagtcttgaa agaagtcaaa
    23821 aaaagtgatg gacgtatcct cttgttcatc gatgaaatcc acaatatcgt aggggcagga
    23881 aaaacagaag gaagtatgga tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa
    23941 ttacatttga tcggtgccac aactttagat gagtaccgtc aatatatgga aaaagacaaa
    24001 gcgttggaac gtcgctttca aaaggtatta gtcaaagaac caacagtgga agatacgatc
    24061 agtattctgc gtggattaaa agaacgtttt gagatccacc atggtgttaa catccatgac
    24121 aacgcattag tagcagcagc tactttatct gaccgttata ttactgatcg gttcttaccg
    24181 gacaaagcaa tcgatttgat cgatgaagcc agtgcaacga ttcgggtaga aatgaactct
    24241 atgccaacgg aattagatca agttactaga cgtttgatgc agttggaaat cgaagaagct
    24301 gcactgaaaa aagaatcaga tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa
    24361 ttagctgaac ttcgtgaaga agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa
    24421 gaagtcaatt ctgtttcagc aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa
    24481 gatgcagaaa ataactatga tttagaacgc gctgctgtat tgcgtcatgg tacgatacct
    24541 caattagaaa aagaattgaa ggaattagaa gctaaagcaa aagacagcga gattaagatg
    24601 gttcaagagt ccgttaccga aaatgagatt gctcaagtcg ttggcagatt aacgggtatc
    24661 cccgtaacga aacttgtaga aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt
    24721 cataaacgag tgattggtca agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt
    24781 tcacgggctg gattgcaaga cccaaatcgt cctctaggtt ctttcctttt cctaggacca
    24841 actggtgtcg gaaaaaccga attagcgaaa gcgttagctg agaacttgtt tgactcagaa
    24901 gatcatatgg tacggatcga tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta
    24961 gtcggagctc ctccaggcta tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc
    25021 agacgaaatc cttatacaat cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc
    25081 ttcaatatct tgttacaagt cctagatgac ggacgcttga ctgattcaaa agggcgagta
    25141 gtagatttca aaaatacggt tctgatcatg accagcaata tcggttcaca gttactgctg
    25201 gaaggcgtga ctgctgatgg aacgattcca gaagcagtgg ctgaacaagt caacacgcta
    25261 ttacgtggaa acttcaaacc agaattcttg aaccgaatcg acgacacgat tttatttaca
    25321 ccattgagcc tagacaacgt gaaaggaatc gttgacaaaa tggtggcgca attggcacaa
    25381 cgtctggaac atcaagaaat cctgctgaca atcagtgatg aagccaaaac gtggattgct
    25441 gaaaatgctt atgaaccagc atatggtgca agaccattga aacgatttat cactaaggaa
    25501 gtagaaacac cactagctaa agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta
    25561 acgattactt tacttgatgg acaacttcat ttcaaaacag aagagctaga agaaatcgtc
    25621 taatcttcca ttgagactat aaaagaaaaa aggggtctga cacaactagt gtcagacctc
    25681 cttttttcaa ataaacagtg ttccagaagt agtttcttcg aaaaataagc cgaaatttct
    25741 tgaagctgcc cgcttctgtc acaacctctt ttattaggta tttttcactt tttctaattt
    25801 ataactttca aagtaacgct catctttttt actttgagac catgcaaaca atcccattaa
    25861 ggcagcacct atcgtatttg tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc
    25921 gacaaacagt gtgccatcag aagcagcaaa acgttgaaga ttcatgccta agaactggtc
    25981 gcataagaat tcccagaact cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa
    26041 taagaggaac aaccaaggac tggtttttga tatctcagca tctttcatca agtaaccaat
    26101 caatccatag ccaagagctg tcaggaccat tggactcacc gcatgtaaga ttttgtccca
    26161 aaaagagatg atactgatca aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa
    26221 aaaccagtaa aacaaaacga ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac
    26281 ttgtggcatg aaaatcaatg caatccctaa taaagattcc acgataaatg tgattccttg
    26341 agaagtcgaa tatttttgtg tgataaattc ataaaaatta tagcagacaa cgaatacacc
    26401 aaaagcaagt aaagctattt gcaccttttt gatttcttta atcactgaaa gtccctccat
    26461 ctaaaaatct ttttacttct gaaagcaact caatttctga agaaaccact tttccgttca
    26521 atttgatcaa acctattgta tataagttca ggtagtgaaa ttgattttca gctgtttctt
    26581 gtagtgcagc gatttttttc gggtgggttc cgccttgctg tcgagtatca gtatataagc
    26641 cgatcactgg gatgcctttc gcataagcca caccgatttc cgatgctacc ccggcatcga
    26701 tcgtcagccc atctagtaaa gcaatcatta aatcactagc caacactttt tctgtgtcag
    26761 caagagcaat cattcgactg tctgcataag cagttttgtc attgattgct tcattttctt
    26821 gaggaagata gatcgaaagc tcagaagaga gctctctgat ttctttaact aactgttggt
    26881 tatataacaa atcactttta gcaaacattg gtgcggcaaa ataaattttc atctaaacat
    26941 catccttttt atcaaaaata atcgctaaag taagcttcca tgtttggaat gatacgctct
    27001 agtgacttca gtgtttcttc atctgtttct aaccgttcga ttcttgccaa ataagaagca
    27061 cggcgataat tcatcatcaa gcaagtcaat gtttggatat ccagtcgaac ggattttcct
    27121 ataggttcat ttaagacacg gacttgtccc tgttcatccc atgttaaagc gaagacacca
    27181 ttattccaag gagcgacagg atcttcaatg atgaaatgaa aagcatcagc tgttccaaca
    27241 aacggaaacc gttgaaggaa ttcttttaca tcaacgatcc gagccataaa atatggttcg
    27301 atctgctctt tgatctgact atcttcaatc aaaaatgcta aaggctcatt tttataaata
    27361 tctccatgta cccagtagat catggaaaaa tgtgcggaaa taaagttcca taagccattt
    27421 cgagcttctt gatcaagata gaacatttct tttacgtgaa atatttcttc agctacccag
    27481 tagaacagaa cacctcttgg ttcatggttg ctatcgtagt agacagcggc tgtgcgctca
    27541 tcttcatttt cgaaacgcca atactcttcc caatgaaaat cactgcggaa taaagcacca
    27601 tggttttgtt gggcaaattt gtcataaacg gaaaatacgt ctggatgatc aactggtaat
    27661 cgctcaacca taccacttac tgggatttgt ttaggtagct gtgtatctct gattttaaag
    27721 gaaagtttat cagacatgat ttcccatcct ttacgccgat agtaggggat actgtaagga
    27781 tacaaataag agatccattg cttattcttg cgcatattat ccaatgcaac gataattaga
    27841 tcttgcatca atccatggtt agcatattct ggataagttc caactccagt cacaccaccc
    27901 attttataac gtgcaccgtg aatattgact tcacaaggat agatagcgat ttgagagatc
    27961 agtttatttt cgtggaacca tccgaacact ttcgatactt ccaaaatcgg ttttttggaa
    28021 cggataaaag ctcgtttatt ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg
    28081 aacacatagg aaagcaattc attgaattga tcgatatgtt cttgagtgac cggttttaat
    28141 tcaagatttt ctctaaaatc tttttgatcc attttttcat ctccatttat tagcttgata
    28201 acagtatagc aaaattctac aaaaaaaact tctatagctg actaattaaa aactctttaa
    28261 attactgctt ttcgttggta taatggaaag tgctgattat atgaaaagag gagacgctat
    28321 ggatataaag aaaatgaaag aacgccaaga gcagattcgt aatttttcga tcatcgctca
    28381 tatcgaccat gggaaatcta cattggccga tcgtatttta gaaatgacgc acactgtgac
    28441 gtctcgcgaa atgcaagatc agctgttaga ctcgatggat ttggaacgtg aacgtggaat
    28501 cacgattaaa ttaaatgctg tagaactcaa ttacacagcg aaaaatggag aaacatatat
    28561 ctttcacttg attgacaccc cagggcacgt cgacttcacc tatgaagtct ctcgaagcct
    28621 tgctgcctgt gagggtgccg ttttagtggt cgatgcagca caaggaatcg aagcacaaac
    28681 attggccaat gtttatttag cgttagacaa tgatttggag atcctgccag tcatcaataa
    28741 aatcgaccta cccgcagcag atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg
    28801 aatcgatgct agtgaagctg tattagccag tgccaaatca gggattggga ttgaagatat
    28861 tctcgagcag atcgtggaat atgttcctgc accaagtgga gacttagatg caccgctaaa
    28921 agctttgatc tttgactcta tttatgatag ttaccgcggt gttgttctaa atgtccggat
    28981 cacggacggt atggtcaaac ccggagacaa aatcaaactg atgagtaatg gcaaaacatt
    29041 tgatgttaca gaggtcgggg tcttctcgcc aaaagcagtt gctagagact ttttgatggt
    29101 cggtgatgtc ggttatatca cagcaagtat caaaactgtc caagatacac gagtagggga
    29161 tacagtaacg ttagcagaca atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa
    29221 tccgatggtt tattgtggtc tttatccaat tgatacttct cgttacaacg atttgcggga
    29281 agctttagaa aaactgcaat tgaatgatgc tgctttacaa ttcgaaccag aaacctctca
    29341 agcattaggt tttgggttcc gctgtggatt cctcggactt cttcatatgg atgtcgtcca
    29401 agaacgcttg gaacgggaat tcaatctaga attgatcacg actgcaccat ccgttattta
    29461 ccatgttaat aaaacggatg gtacgactgc tacagtagat aacccggcag attttcctga
    29521 acctgtaacg attcaggatg tagaagaacc attcgtcaaa gcacagatca tggtcccaaa
    29581 tgattttgtc ggtgcagtaa tggaactttc tcaacgaaaa cggggagaat tcattacgat
    29641 ggattattta gatgattacc gagtaaatgt cgtctataat attccgcttt ctgaaattgt
    29701 ctttgacttt ttcgacaaat tgaaatcaag cacgaaaggc tatgcctcat tggattatga
    29761 aatgtctggt tatcaaaaaa gcaagttagt gaagatggac atcttgctga atggagaaaa
    29821 agtcgatgca ttaagcttta tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat
    29881 cgttgaaaaa ctgaaaaaac taatcccacg ccaacaattt gaggtgccaa tccaagcagc
    29941 tattggacaa aaaatcgttg cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc
    30001 taaatgttat ggtggagatg tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg
    30061 gaagaagcgg atgaaacaaa tcggctccgt cgaagttccg caagaagcct tcatggccgt
    30121 tctgaaaatg gacgaggacg aaccgaagaa atagcaaggg tttgtttgaa aacagtgtaa
    30181 aaaataaacc atgtttacat ggatttgcca ccggtttgcc accggtggtt tttttcggtg
    30241 gcaaaaatca agaattcttt ctaagatttt ccatgatatc gaccgtttca tttctcatct
    30301 tatctgttac atgcgagtaa gtatccatcg taattgaaat tctgctgtgg cccaatcgtt
    30361 cagagatttc tttcattttt gcgccatttt cgagaagaag tgtagcatga gtatgtctga
    30421 gagaatggaa gttaaaagag agggagagtg cattcgatat cctcctagta ttccatttca
    30481 ctacacttgg cgtaactagc tcaccgtctt ccttcgtaca tactgcattt gaatcaatgt
    30541 agagctttcc atacttcatt cgattttcta attgttgttt cttatgtttt ttcagaattg
    30601 ctagcaaggt ttgtccaata aaaatcgttc gattggaact gcttgtcttt ggcgtaccat
    30661 atacccatgc gccgtcattc tttaccattt gtttctctac agtaattgtt ccatttgaaa
    30721 aatcgacatc atcccacgtc agaccacaaa cttcgccaac gcgcattccc gtataaaatc
    30781 caatattcaa aggaatatag aaaggatgtc cttcaggagt aatttctagc atatgatcaa
    30841 agtcctcaag agaaatgatt tttagatctt ttttagtcgt tggtcgtgct tcatattttg
    30901 gtatttttac atacagcata ggattttgct tgattaatcc ccaaggataa accgccatat
    30961 tcagcgcatt cttaaggaca gagtgagtaa tagtcattgt tttcttcgag taaccctttt
    31021 taaattcagc attgatgaaa ttttgtaaaa gagcagggga gagatccgta agttttttct
    31081 ttcctaaata accgtttata tgatttttga tggtaaatcg gtagttttca taggtattgt
    31141 attttagatt tagtttaacg tattcctcca tccaaaaatc aaggtattgt tttactcgag
    31201 tatccgtacc taaaaagtat tgtcctgttt cgtcaatatc tgataaaact tttcgtaaag
    31261 cagcttcggc ctctggtcgg gtgtctccgc caactttctc cacttttttt cttgagccat
    31321 catcattgat atct
//
LOCUS       DAIGUC010000034        30850 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.034, whole genome shotgun sequence.
ACCESSION   DAIGUC010000034 DAIGUC010000000
VERSION     DAIGUC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.034"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(116..661)
                     /locus_tag="NOB46_001649"
     CDS             complement(116..661)
                     /locus_tag="NOB46_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1058584.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(673..1365)
                     /locus_tag="NOB46_001650"
     CDS             complement(673..1365)
                     /locus_tag="NOB46_001650"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCI1058585.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1384..1668)
                     /locus_tag="NOB46_001651"
     CDS             complement(1384..1668)
                     /locus_tag="NOB46_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058586.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1681..2244)
                     /locus_tag="NOB46_001652"
     CDS             complement(1681..2244)
                     /locus_tag="NOB46_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI1058587.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2472..3134
                     /locus_tag="NOB46_001653"
     CDS             2472..3134
                     /locus_tag="NOB46_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCI1058588.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3258..4454
                     /locus_tag="NOB46_001654"
     CDS             3258..4454
                     /locus_tag="NOB46_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCI1058589.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4555..5931)
                     /locus_tag="NOB46_001655"
     CDS             complement(4555..5931)
                     /locus_tag="NOB46_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1058590.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5968..6834)
                     /locus_tag="NOB46_001656"
     CDS             complement(5968..6834)
                     /locus_tag="NOB46_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HCI1058591.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6923..7948)
                     /locus_tag="NOB46_001657"
     CDS             complement(6923..7948)
                     /locus_tag="NOB46_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1058592.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7966..8640)
                     /locus_tag="NOB46_001658"
     CDS             complement(7966..8640)
                     /locus_tag="NOB46_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1058593.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIKGYIETKVG
                     QGYIVP"
     gene            complement(8824..9717)
                     /locus_tag="NOB46_001659"
     CDS             complement(8824..9717)
                     /locus_tag="NOB46_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI1058594.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9791..11488)
                     /locus_tag="NOB46_001660"
     CDS             complement(9791..11488)
                     /locus_tag="NOB46_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI1058595.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11481..12794)
                     /locus_tag="NOB46_001661"
     CDS             complement(11481..12794)
                     /locus_tag="NOB46_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCI1058596.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12794..16831)
                     /locus_tag="NOB46_001662"
     CDS             complement(12794..16831)
                     /locus_tag="NOB46_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI1058597.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FHHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16844..17302)
                     /locus_tag="NOB46_001663"
     CDS             complement(16844..17302)
                     /locus_tag="NOB46_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1058598.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17600..18118)
                     /locus_tag="NOB46_001664"
     CDS             complement(17600..18118)
                     /locus_tag="NOB46_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI1058599.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18120..18737)
                     /locus_tag="NOB46_001665"
     CDS             complement(18120..18737)
                     /locus_tag="NOB46_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI1058600.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18734..19588)
                     /locus_tag="NOB46_001666"
     CDS             complement(18734..19588)
                     /locus_tag="NOB46_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058601.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19585..20496)
                     /locus_tag="NOB46_001667"
     CDS             complement(19585..20496)
                     /locus_tag="NOB46_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1058602.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20537..21871)
                     /locus_tag="NOB46_001668"
     CDS             complement(20537..21871)
                     /locus_tag="NOB46_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1058603.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22079..22909
                     /locus_tag="NOB46_001669"
     CDS             22079..22909
                     /locus_tag="NOB46_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCI1058604.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23153..23471)
                     /locus_tag="NOB46_001670"
                     /pseudo
     CDS             complement(23153..23471)
                     /locus_tag="NOB46_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23593..23787)
                     /locus_tag="NOB46_001671"
     CDS             complement(23593..23787)
                     /locus_tag="NOB46_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058605.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24292..24477)
                     /locus_tag="NOB46_001672"
     CDS             complement(24292..24477)
                     /locus_tag="NOB46_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058606.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25327..25668)
                     /locus_tag="NOB46_001673"
     CDS             complement(25327..25668)
                     /locus_tag="NOB46_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1058607.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(25668..25898)
                     /locus_tag="NOB46_001674"
     CDS             complement(25668..25898)
                     /locus_tag="NOB46_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1058608.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26185..26523
                     /locus_tag="NOB46_001675"
     CDS             26185..26523
                     /locus_tag="NOB46_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058609.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(26728..26967)
                     /locus_tag="NOB46_001676"
     CDS             complement(26728..26967)
                     /locus_tag="NOB46_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI1058610.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(26943..27290)
                     /locus_tag="NOB46_001677"
     CDS             complement(26943..27290)
                     /locus_tag="NOB46_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI1058611.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(28022..28603)
                     /locus_tag="NOB46_001678"
     CDS             complement(28022..28603)
                     /locus_tag="NOB46_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1058612.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(28786..29412)
                     /locus_tag="NOB46_001679"
     CDS             complement(28786..29412)
                     /locus_tag="NOB46_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1058613.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(29434..30765)
                     /locus_tag="NOB46_001680"
     CDS             complement(29434..30765)
                     /locus_tag="NOB46_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HCI1058614.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
BASE COUNT         9097 a         6595 c         5238 g         9920 t
ORIGIN      
        1 aaagaataag tttttttaaa ataacgtata aaaaagagca taaaacaaag tcgtttgttt
       61 tatgctcttc ttttattatt ttgtgctttt tattttatca aatcactttg tttttttata
      121 aaatttctgc gcctagtgtg gactcaaaat gtctcaatgc ccattcatgt ccaacgggat
      181 cgaaacttgc cacggaatct ttgaaaatat ggagtttgta tcctagatta tacgcatcga
      241 ctgctgtatg caacacacag atatctgtac atacgccggt caaataaata tctgtgatct
      301 ggcgttctcg caaacggatg tctagatctg ttccactaaa agcggaataa tgccgtttgt
      361 ctatccaata aacattttcc tcttgctcat agtcttggta taaacttttt aaagagccgt
      421 acaattcccg tccacccgtt cctatcacat tatgcggagg aaataagcgg ttctccggat
      481 gaaaggaatc ttttggatca tgcgcatcaa tggcaaaaac gacaaaatcc ttttgatcaa
      541 taaacttctt tgtatgagca gtcagctttt tttcaattac ttgtcctgct gtcccagtag
      601 tcagctttcc atcctctgca acaaaatcat atgtgtagtc aatcgagatc aatgcgttca
      661 tcttagtcct ccttatacga gatgtttgac aaattcgatc accatttctg ctgatcgttt
      721 gcctgcgtct tcgataaatt cgtcaaagct ttgtgtcgcc gagtgatctg ctgtgtcgct
      781 cattgcacgt acgatcaaaa atgggatatt gaactgacga gctgtttgtc caacagcggc
      841 tccttccatt tcgcaagcta atgcttcagg gaaattcgtt aagatttctt tgattttatc
      901 tggcgagtcg acaaatgtat cacctgtaac gatcaatcct tcttttgcgt tcaaattcgt
      961 tgcttttgct gctttaacca tttcactgcg caaatatgtg cttgcttcat aatatagagg
     1021 cattcctggt aattgtcctg ggttgtagcc aaatcctgtt gcatctgcat caaaataagc
     1081 tactttgtct gatataacga tgtcacctac ttgtaagcct tcaccgattc cgccagctga
     1141 acctgtattg atcaccatgt tcacgccgta ttgttggatc aacagacttg tggtaataga
     1201 tgctaagact tttcctatac cggaacgtac gacgatcact tcgtggttac ctaatgaacc
     1261 tgaaataaat aaagcgcctg cgcgttccca tgataatggt tcgcttaggt tctctctcaa
     1321 aatttttact tcttcttcca ttgcgccgat aataccgatt ttcatctttt taattccttc
     1381 tttctatata aatgcgattg ctaaaaaaac cacacataac attaggataa caataataag
     1441 agatttcatc aaaaaagagt tccatttggt cgtcttttcc cgttcgctga tccttgtttt
     1501 cgtgattggt ttattctttt tgctttcttt acgataaaag ctggcaatct ttttttcttc
     1561 ttgctgataa gctgtttctg cttttcgctg tttttttaat gactcgcttg cttgtgcttg
     1621 ttgtcgcttg cgaagttcgc ttcgcgtaat aagcggtcct ttggccataa gccgatccct
     1681 ctactttcct ttggtcaata gttcccagta ttgaatcgca taaatcgtct ttgcatcaca
     1741 aatcaactga tctttcatcg cttgttgcgc ctcttcaaga gttagatgat acaactccag
     1801 tacttcgtct tcatcttgtg ctaaaggatt ctcgaccttc tctacccctt gtgcatgata
     1861 aatatgaagg acttcatttg caaaacctgg tgaaagatac atcgaagtaa gatggctcag
     1921 cgacttcgca cgatagccag tttcttcttc taattctcta gctgctgtca tttcgggatt
     1981 ttgtccttct cctggatcga tttttccagc tggaatctcc aaaatcactt tttctaaagg
     2041 ttttcgaaat tgtttgacaa gaagcagacg atcttgttcg tcaaaagcaa tgatcccgac
     2101 accgccagga tgaaatacca gttctctctt cgaagttcct ccatctggca aacgaacttc
     2161 gtctacagca acatcaataa tttttccgct atagatttct ttgcgactga ttgttttttc
     2221 ttcaaattgc tcattgttca gcatatcttc tcctgctttc tttgtaatca taactgcttt
     2281 tttttcattt ttcaattttt ctcaaaaact ccttattagt ttaccataga taaaccttag
     2341 attttctcta aatatagaaa atccttcttt agtccgatac tctttctagt agtccgtatg
     2401 ctaaaataag tatgtaatcg aataacgaaa agaattcaat actcaacgat aaatgacatg
     2461 gagggtttat tatgataaaa cgaaattggc cgtggcttct agcattggtc ttgctatttc
     2521 tctttgtccg aaacaatagt ttttcttttg ttctaggact tttattgata ggtgtagttt
     2581 tagttttgtg gggactcttt ggttcgcgca ggaaaaaggg aaaacaagaa gaaattcctg
     2641 cactgactga cgaacttgaa actcactatg aaaaaagcgg tatgacagcg aatgaaattt
     2701 cattttttcg acaaacaatg aatcaaacaa aaaatgagat caatcaattg caaatgaata
     2761 tgcagcagac agccaaactt aaagcaatcg atctccgcca tgatccagtc aaagcagcga
     2821 aagctttatt caaagaattg gtgaaagaac caaaccgact gcatgaagca agtcagtttc
     2881 tttatacgca tctgccgaat ctagttgatt tgacaaataa gtataatgag atcaatgacc
     2941 atgagatcaa aaacaaacag acctatgaaa aactagaaga aagcgcgcag atcatcgacc
     3001 agctgtcagc tttaatcgca caagattatc aaaaattcgt tgctgaggat ctagatgata
     3061 tcgacgtaga gatatctgtt gcgaaacaga gcttaaagcg tgataataaa tatgaaccag
     3121 aacaaaagga ttaactcttt tgttcataaa agaagactcg gaacattcag atgatgtctg
     3181 gctgtttcga gtactttttc taaagtagag acattcatgt aagaatcgag aacagattca
     3241 acaaggagga attttttatg gatcataaac cgactgaaac aaaagatgtt acaccagtta
     3301 acgatacact tgaagattta ttgaacaacc cgttttcaac tccaacagat acgctgacca
     3361 cttcacaaca agcggagatt gatcagctcc aagagcaaca gacagctgct cgtttaattg
     3421 acaaactacc ggcggaacgc caagaacaag ctaaacagct agcagcaaaa atcgatgcta
     3481 atgatgcaca gtctgtcatc agctacggat cggctgccca agcaaaatta agtgaattct
     3541 cacaatcgat gttgaatcat gtgcaagcac aagatattgg tcctgtagga gattccttaa
     3601 ctgaactgat gtatcgtctc caagaagcca atcctgacga actgcgtgcc ggagaaggga
     3661 acatcttcca gcgtgtcttc gggaaggtca aacaatcgat ctatgaagtg acagcaaaat
     3721 atcaaaagat tggtgcacaa attgacaaga tttcagtgaa attagataaa gaaaaagacg
     3781 gtctgctaaa agataatctg atgttagaac agctttacca gaaaaacaaa gactactttg
     3841 atgcactgaa tatttatatc gctgctggag aattgaaaat ggaagaactt caaacaacga
     3901 tcattccaga agcgatgaaa agagcagaag aaactggcga tcagatggat gttcagattg
     3961 ccaatgatta cacgcaattc ctagatcgtc tggataaacg tacgcatgat cttcgcttag
     4021 ctagacagat cacgatccag caagcaccac aaatccgttt gatccaaaac acaaatcagg
     4081 ccttggctga aaagatccaa gcatctatcg ctacagccat tccgctgtgg aaaaaccaag
     4141 tcgtgatcgc attgaccttg cttcgtcaaa aagatgcagt aactgctcaa cgccaagtct
     4201 ctgaaacaac aaacgactta ttgaagaaaa attcagaaat gctgaaaatc tcagccatcg
     4261 aaacagcgaa agaaaatgaa cgtggaatcg tggatatcga gacccttcaa accactcaaa
     4321 atgatttgat cgaaacaatc caagagacat tgcgtatcca aaaagaagga aaagaaaaac
     4381 gtcgtcatgc agaagtagag cttggacaca tggaagaaga tctgaaacaa aaactgttgg
     4441 atttaaccca atagatcacc tttcgcttgt tactaaaaca aacgcccaac aacagtttat
     4501 tacaactgtt gatgggcgtt tttcttatct ttcttctaac ttctccattg gagtctattt
     4561 ctcattcatc ttgctgtgtc catagccata gccaaaataa atgatcagtc caataaccat
     4621 tacgataccg aacacgatcc atgtcacagt ttgcagacga agcatcaata caatacaagt
     4681 caagatggag acgattggca atagcggaac gaatggcact ttgaattctc cagcttttgg
     4741 tttgccaaac atttttctca acttcagtaa gcctagacta acaagcatca aataggcgag
     4801 cgccatgata ttcgttagtt ccgctaatac attcaatggg aaaaatccgg caaagaatac
     4861 agctgccaca ccagcggcat aagtcgcttt tttcggtgta cgatgctttt gatcgatttc
     4921 tgtcataaac ttaggaagta agccatcctt gctgacagca aacagtaaac gagcaagtga
     4981 atacatcatc gagatcgtta ccgtcagtag cgttaaaatt gcccctacag cgatcaccgc
     5041 gcccactgtt ccatgtccta catacctcat tgcaaaagcc actgggtcat tgactcctag
     5101 ttcagtatac ggaacgattc ctgtcaagat cagcgtcacg atgatgtaaa ggacagtagc
     5161 aatcagtatc gaaccaatga ttcctcttgg cacatctttt tgcgggtttt tgacttcctc
     5221 ggctgccatt gcaacggcat caaatcccaa gaaagcaaaa aacacaagag ctgcaccatc
     5281 tagcacaccg gaaaaaccaa aaggcatgaa tggctgccag ttatcaggtt taacgaaaaa
     5341 tattcctaca atgataaaca acgcgatgat accaaatttg acatatacca tggcattatt
     5401 caaacgtaat gctttcttgg cttcaagcga cacgatgtaa gtgacgaata tcactacgag
     5461 caccgcaatc aagtcaatgt atgtaccatt ttccggattg tacccgccag ttaatgcttg
     5521 tggaagttcg gcccctaaac ttttcaaaaa accttgcata tagccagacc atccggaagc
     5581 aacagaggaa accgctagta aaaattcccc gatcaacaac caccctgtca gccaggcagc
     5641 aaattcacca aatacaacat acagataggc atatggccca ccaatcactg gcactcgcga
     5701 agcaaattct gcgaaactta gtccagacaa aatgacaacg attgcagcta agacaaatga
     5761 aagtgacagt gctggaccag cattttgatt ggccgcaacc cctgtcacca caaatattcc
     5821 cgtaccgatg atcgcaccaa ttccaagcat gatcaaatca gacgttttta gttctttttt
     5881 catctcactc gtatgattga gattgatctc tttcttacga aacaaatcca ttgaagttcc
     5941 tccccatttt aggttggaaa acagcgatta aactgttttc atatacccta aaaggatacc
     6001 acctaaaatg actaaaaggc aaccaacaat aacataaatg agctcttttt tcgtttttct
     6061 ttcgccaagg atgaaaatcc cacctaaagt agagataatg atccccattt gtgaaagtga
     6121 gaagccaaca gctaaaccaa gtgatttgac tgttagaagc atgcagatgt ttcctaagcc
     6181 ccataataat ccacagatca tgtttttcca cacaaactga tcgactttaa ctttacggaa
     6241 agcaaagaag cttgcgccta agatcattcc gatactttga ggtaagataa ttgacatcgc
     6301 atccaaattc gcccagttga cgatgatggt atatacacca taaccaatcg tagagaagat
     6361 caatgctcta aaacccttac caaaatcaag cattttatta tctgtatcta tttttccttc
     6421 gtcatcttgt cgggcagtca aatacgcacc gcttacaaga agagctaaag caataatacc
     6481 gtatacataa tctttcgttt gtgtccattc atggaagaaa acggctcccg caatcgtatt
     6541 caaaattaat tgaaaaccag tagacaatgg tagccctaca gaaacaccca tgtacttcat
     6601 tccatggaac tgtccatttt gtccaacact ccaagctaag ccggataaaa atccgatcaa
     6661 gaaaatccaa ggggtgatta caggactaac aacgaaaaag acaactaaag aaaacagaaa
     6721 tgcaccgatc gtcattccta gtgtttgttg attggcatcg ccaccaattt taccacttac
     6781 taaaccaata ctaccccatg ccaacatagg gactaatgct attaaaattt ccataaccaa
     6841 tctcctttta tttcacatga taagaaactt atcagcgaaa acgttaacaa cacaagcact
     6901 ttttttcgtt tctaacgatt ttctaacgtt tttcattata aaaatttaag attgggaaaa
     6961 ataaagtcat tgttgtccct tttccttcag ttgattcagc cgtcaaatgg atacctaatt
     7021 tttcggccag attttttgct aaataaagtc ctaatcctgt tgaatgtgtt ttgctaagtc
     7081 gaccatttct cccagtaaat cccttatcaa agatccgttt caagtcttcc gctgggatac
     7141 cgatccctga atctttaact gaaaggctga ctccttgcgc ttccttttct atgctcacaa
     7201 tgatgtttcc gtgatccggc gtatatttga tggcattact aagcaattgg ttgaagataa
     7261 aagcgatcca tttagcatcg gtcaaaacag tatgatcctc accaacgatc tcgtagcgaa
     7321 tatttttttg gataaaataa tttgcctgac tgcgtatcac aggctgaatg attcctttta
     7381 gtccatattc ttggatgagg tagtcccgcg agaaactgtc gagtcttgca taatacaaaa
     7441 cttgttctac gtattcatcg atttttgata attcattttc tagtaatgta tacttttgat
     7501 cgtcaatatc gaactcgatc gaacgaacta gcaatttaga agcggaaagt ggcactttga
     7561 tttcatggac ccatgagtca atataatctt tttggtcttg ttgattactg attgctgatt
     7621 gcattacttc ttggtgttca cggatcagct gattgatata ttcttctacc agtttttctt
     7681 cttctgtcct cccaccactc aaataatttt gcaaagggga agttttttgt atgtcggcta
     7741 attttcccca ccatcttctc ttgctcaagt aaccacccag cagataaaaa atcagaaaga
     7801 cgccctcaat caaagctaaa taagcaattg tgctcaaatc aactttgatg tttggcgcca
     7861 gccacatcac aaagatcgtc aatgcaataa aaaacagcca tcccaagatc aatgtccact
     7921 gatctttcaa atatttaaaa aaattcatct taaccgctca tcctttcagg gaacgatata
     7981 tccctgtcct acttttgttt cgatatatcc tttgatacct gcctgttcga tttttcggcg
     8041 taaccgattg atgttgactg tcaatgtatt gtcatctaca aatcgttcgt catcccacag
     8101 tgctcgcagc aatttttccc gacttaagat ctttccattg tgcttcatca aaataaataa
     8161 tagacgatat tcatttttgc tcaaatcaat gatctctccg ttgatttcca tacttccgtt
     8221 gtcaacattc aacgtaatgc cattgtggct catcatttca ctagataatt ctgtgtagtt
     8281 gtaagaacgg cgaagtaatg cattgatttt tgcaatcagt acatcgattt ggaaatgttt
     8341 tgtcacaaaa tcatctgccc ccatgttcat agccatgatc atatccatat tcgtattcct
     8401 gctggagata aaaatgatcg gtactttcga tacttcacgt attttttgac accaataata
     8461 gccatccaaa acgggaagat taatatctag taatacaagc tgtggttctt ctctttcaaa
     8521 gtctgagaac acttgattga aatcggtcgt tccaaaggtt tcaaattgcc atttctcaag
     8581 ttcctccatg atcaattgtc gaatgatctc ttcgtcttcg actaccatga tttttgccat
     8641 aaaaaatccc tccatctttc ttcttgctac tacaatatca aagaagccct tgtgaaacaa
     8701 gttggcttac ctggaaaatg tcattttagc aaacgttaaa aaaaactgga aatatgcgat
     8761 ttaatcgcgt ttgtctcttc caagcagctt aaatttatta tgttattctt aataattggt
     8821 ctattatctg ttatttttct ttcgttgttt ttgtctttta aattttcgat aacaccaata
     8881 accgaaaagc gttagcacta gcaatatacc tagaaggagt ataagtaatc gataaagatg
     8941 gtattttttt gtctgttcta tctttgaaga gacttcttct gtaaagggaa ctcgtcttcc
     9001 tgtcactagt aatcggtgag tgttcacggt gtaaggtgta caagtgataa gtgtgactag
     9061 atcctgcttt tctctaattg ctaatgtatt tgtttttgtt ggaaggacaa caattttctc
     9121 aacgacttca taagcgagca tccgaccata cacttcaaga tagaatcggt catcttgctc
     9181 catttcttca agatccgtaa agagtttttt ctcagcaata ccgctatggg cggtaatcac
     9241 ggaatgtgta ctctctcctc cagttggaaa agaggtgcct tgcaggactg tcgctcctct
     9301 atctaacaaa agatcattcg tttcatcaaa taaaggcaag ctaacattga ttttcggaat
     9361 atagatggct ccgatcatat gttgttcgta atattctttt cctggatttt ggacatttct
     9421 aaccgcttgc tcaaaaggat ctttgacttg tcccattcct gggattactg atgtatgagc
     9481 aagcgtctga tttttctttt catgcactgc taattgttgc tcatgttttt cttctttatc
     9541 gcgttcaagc tgcttttgat aattctcgat ccttctttga tccaaataat tgctgagagc
     9601 atctgctaaa aatggatatg taaaaactgc agctccggca agaaacatca ctgccataaa
     9661 taattgtaat aaaagactga tttgggtttg aggtctatta cctattttct ttttcatttt
     9721 cttcaccttc ttatttaaaa aaactgcagc aacctttata aaaccgattg ctgcagctta
     9781 tttttgttgc ttatacttca gacttcattt tagatttacg gtaccagctg tacgctccaa
     9841 tcatcaaact tattccgatt agtaagaatg ccaagagccc gttcccacca gtagcaggaa
     9901 gtgacccgcg tttcatattc ggtactcttt ctggccctgg attttctact cctacgatct
     9961 gaatttcttc attatagctt ccataagaga tgataaattc agtaaaggct gcctcacctg
    10021 ttggaagtac ataaccttct ggcgccatgg tctctttcat ttgataggtt ccataatcta
    10081 acccttgaac ctcaaagtat ccatttccat ctgcgacaaa ttctgttgct tgtccgcttg
    10141 ttgcccactc aattctatct gctcctgatt cataaacagc taaaggcgac tcccctttat
    10201 aaaatattgc gtattcagaa cggtcttcat tccacaattc gaatcttgca tctttaagca
    10261 attcactgct tgatgcatca tatttttcaa actttcttcc acctgttgtg actttctctg
    10321 gcggctctac tccttcttca taatcaaatt catcatttcg tccgatttca ataaccgctg
    10381 tgttgttatg gaaatcatcc gcttctagtt ctgtggaaac cttcaaatta tacgtgatcg
    10441 ttaaatctcc tccacgtgca tctgctaatc tacctaaagt atctactttg gctactccat
    10501 tttcttctgt caaaatcgtc acgacaaacc cgttgcttac tacttctact atataatctt
    10561 gtccttttgt taaaatcgtc tcgccggctc gcacttctat ttcctgatca taataagtta
    10621 gaccaactgt aggcgtatct gtgattttgt aatttttgat aacagcgctt ccgttttcaa
    10681 ggacagaatc gatgaaataa ggaataggtg ctgtgatcgt gtaagaagcc gtttttcctc
    10741 tttctagatc aatataagaa atcgtttctt gttctccagc ttcattaata atcgttactt
    10801 gtctaaggtc gctttcctct acattcatct gtttatctgc ttctctgatt tcgtttttcg
    10861 gatacaaatg cacatctgta ttgtatgtgt ctttccatgt agaaccatcc cacacgccat
    10921 ccaccatatc aggcatcatc actggcatca taacaaccat tggagacgcg attctggaaa
    10981 tatgagctgg cgaataagtt tctaagaaaa gatagacttt atctctagaa gaaggtgctt
    11041 cttccgtcac ttggacggta gagaataccg cttctccagc ttcattcgtt gtttgtttgt
    11101 caatacttgt cagtcgatat tttaaaaacc aactttctgt gtgccgtttt tgaatccatt
    11161 caatcgcttc ggcagaatta agaccgtctt ctcgttccgg tgttaaagga ttatctcgaa
    11221 tcaaatcgta atatacttcc gttacgtcaa acaaatcaaa atcgactcct ggaatatttt
    11281 cttcaccaaa atccgtagaa accaatccgc tattcggtcg ttcttccgga acagatgaga
    11341 aacctttttt gtgtaatgta atcgtcactt cacttggttt ttgtgcgact tcttcggctt
    11401 tgactagttt tccgttcccg aaaatcccta ttcccgcagt aacgagtaac agtacactca
    11461 ttcccgtgac aatcattttt ttattcattt ttttctcccc gttctttttt tattaataaa
    11521 acagcaccta acaataaaag aattcctagt aaagaaatca acgttcttgc ttcattcgtt
    11581 tgcgggaata cggaccattt tcctgattga cctggattgc ttggaccact cggctctttc
    11641 ggtttgtccg ttgtttcttt tacggtctcg ttataaacac gtggtgttgc ggattcatag
    11701 gcagagactg gaactttccc ggattctaat tcagccatct cctgtccgtt aactactaca
    11761 tattgtggtt ggccttttgc atccacccaa aattcaggga tgatgacctc gattctctta
    11821 cttgcttcat ccatctcgta accttccaca ccttttaatt cttcaaaata ataggtgcca
    11881 gaaggcaaga aacgttgtcc tgtcgtaaca aggccctctt tatccgaaat gaatttgctt
    11941 acatttttgt cattcaaagg atcattgtct gctggtttga tccattgatt tttcaagtca
    12001 ttagcaggag ccatatctaa ataatatttc cccccttcta tcatctgata tagagcaaaa
    12061 acagcacctt ctaatggttt tcctttttca gttgttcctc tttgacgtcc atacttgaag
    12121 aagtatggat ctcttagata accgacattt ttaggataga tatgaatctc ttgcagttcc
    12181 tcggttgatt ctgtcgggtg ataaattggc aaaatagcag caattgggat agctgtctga
    12241 tcgatatcaa catccaatcc aacttctgga tcaatcgatt cttcgaaaat caaataaact
    12301 gcatcccgat cttggttttt cttaggtgct ttgatacgtg caatcccgtc tcctaatccg
    12361 ccaaccgtat ctttcccagt tgttaccgaa gtccctattt ggacaagcct ttcttctgtg
    12421 attagctgac ggatattgtt tctgttcgtt tcagcgattt gctggacgaa ttctttagga
    12481 gtcatgtttt cagcagcttt tttttcatga taataatcgg tcatgtcgta aatggcaaat
    12541 gtcgctccat ttagtggcac cgtctgtgaa atgatatctg ctgtttcccc tgcttcctca
    12601 gagatagcca agccatcatt ttcatggtat tcaaattgat cgttataatc gatatctcga
    12661 atcatccgtt tatgcaacac gaattccacg acatcttccc ctgattcttc tgccgacatc
    12721 gcatgtggaa gaaggactgc tgcaagcggt agtaaaacaa gtaattgaag catcaaacac
    12781 aacagctttt tcattacctt gctccctcct ttttagattg tctgacaaac aaaccatagg
    12841 ctgctcctgc aagcgccatg aagaatgcag caagcaggat atagaataat cgtccggatc
    12901 ctcctgtagc aggcaacgga ttttcaggat cgttcccgac actaagctgt aatctgattc
    12961 gatttgtctc caaaagttca tattctaact cttgctgtag atcaggcgtc tctgcttctt
    13021 cgtttggata atacgaaatc tcaactttta gtgtacccgc ttcttttcct ggaactaccc
    13081 gatcattttc tatgtcaggt tcttctcgat aactaatttc taaaataaag taacctggaa
    13141 gttttctata gctgtcaggt gacttcactt ccttgatccg atagacccct tccaacaagt
    13201 ctgaagcatt gaatagggaa gaatcgtttg gatctggtgc caagcctccc tcgatgattt
    13261 catactctcc tgcactattt tgtttctcaa ttgaaaattc tgcgccttca agacgtcggc
    13321 tattcatact gtcaattttc aaaagttcca aatcgattgg cgctagttca tcttctaagg
    13381 ttacttgtag tacaccatcg atgatttcat agccttccgg caagggagca gtttcgtctt
    13441 cgatgaccgt atcttcaatg ataaacttac cttcttcatt cagtgcaaac tggaacactt
    13501 gatcagatag ccgataccca tttggtgcga cagattccga gacctcatat tcaccaatag
    13561 acagatgcag aggttggtcg taatttaaat cgacatactt ttctactcct acggcacgag
    13621 aatagaagta tccgatccca ggcaaacgtt tcgattcttc tggttctaac ggattaccag
    13681 tgtatgctcg atacagcggg aaggaagaat cccccacttt cctgatatcg aaacctgcac
    13741 catctaatgt atggccttca tggtctaatt ttctaactcg gatctcccga taatcaaacg
    13801 tattgtaagc agtgaatgct acccataaac gatcctcttc atctgttgta tacgtgagat
    13861 attgccaatt ttcttcacct gtttgcttga gttggatagt ccctatagca ttatcgtaaa
    13921 gtcgcaagat ccatgtgtca ttttcatcag gttctttgaa accttctggg ttctggctct
    13981 caatgatttt gtattctgca tagttggtag tttcttcact atccttataa acaaatgaat
    14041 ctggctctcc gattggatga ataactttct caccatccac gattacatat ttcccgtctt
    14101 catctactga atagaacgtg agtctccctt tctcttcctc tacttcgttc acaccagaaa
    14161 gccctttcgc tactggatat ccgatttcca gtccgttacc atctgtttca taaagttcaa
    14221 actctgcgcc attgattggc atattactgc cttcaattag tttattgata ttcatgtgga
    14281 ttggcttgaa ttcatttcgc atttccagtt tgacatacaa ctcatcatac tctgtgcctt
    14341 ctatgttagg ctcttgtaca acagaaagct tgtgatattc tccttcataa taggaattcg
    14401 gatctttacc ttccggtccg ccgactctcg aaccagatgt atattcatct acaagctcgt
    14461 agtgacctaa catctcatct tcgttggctg catatttttt gatttggaat tgatacgtct
    14521 catctactaa ctgataacgt ggtggtccag cgatctctct gatccaaaat atgtcgctga
    14581 ctgctccagt ttcatctcct aaaatcggca tcttcgtttc aaagatcgct attccgtccg
    14641 tggtagtttt acttgtttcg attggttcgg cttccccact ctctggattt tggtcatata
    14701 atgcaaattc gactccagcc aacggctcgc cattttgacc cttcttgctg acttggaaat
    14761 tacggccttt atgttcgtaa cgaatggaag aagatgggaa atacatccgt ccagtagtga
    14821 tatcattctc ataatcctcc aggttctgaa tataggccat attgttcact gtgcaaaaat
    14881 ttccgtcttg agctcccgca tcaagtttta cttggtactt gatcctgacc atttcccctt
    14941 cacctaaaga aatcggagaa aatttataag cttggttttc ccgtccgaca tacgttgtcg
    15001 gagtcgccac tacttctggt ggggcttgtc catgacgttc ttcatcccat atttctggct
    15061 cttggtactt catgccgttt tctcctggat ctagatggta aaactgaata tctgccgatc
    15121 tgccagctcc aaatggtgag acattaaaac cagtttcatc ataaagtgtg gcttgctgga
    15181 tcgttctctt gaaggtagaa gagatatcct ccaaggctgt aacaatgtca ttcttgttgt
    15241 tcgcattgta atatcgcggt gttacgccat cttcttctaa atcagcaata tttttcaata
    15301 catttcgtcc aatagcatct agtcgttgtc tcccgctaac gtttccatcg attcctaaac
    15361 caatggagaa gatacttggc gggttctctt gatacttgtt tttcagccaa tgatgataag
    15421 caactgtgtt gatcgcagat gacttttctt gcgaagtagg actgccattc gtattgttat
    15481 tagaagaacc atcaccaacc cagtgagtcg ctttattatc tccttctttt acctctccat
    15541 aacgatagtg tacatttact tcatcttctg gacggttaaa gtcagatgca taggtaactg
    15601 gatgagtaaa ccctgcatta gaagtattcc cagaaaactc ctcaaaattt ctgaacaaaa
    15661 cgtcattatc ttcagcaatc ttatcttcca tcacagtcca gttgctccaa gctccattag
    15721 tgctcgtacg ataacttgac tgaatcggtg cataactgaa ggtcggtgtc ccatctccca
    15781 caacgattag gattttttct ggatttctat tttctccgcc attgtcttta tacaatgttt
    15841 catagccatt tttaagccct agtgtaagcg gagttcctcc gattggtgta cgatttaatg
    15901 ctgtattctc acttcccgtc aaacgattga tatcatttgt caatggaaag atgtccgaac
    15961 tgatttgctc atggttattg atagctgtac tattatggtg aaaattcacc ataccgattc
    16021 gaatatccag actcgggtca gagagcagat ctttactcat ttcgtttact gcctcaatca
    16081 acgcagcatt tttagtttga ctattggtcc cagcggttaa ttcactcata ctcgctgact
    16141 tatctagaac aaaaacgata tcgattggac tgatttcctt tttctcgccc ccgatgacat
    16201 ctagatagac attgtaaagg gttgttgcat cttcaggatg tagatcagat gctgtgctgc
    16261 ttggcagaac aggttctacc cattttttga tgtacgcccc gttataatcc aagtaactgt
    16321 tttcaaaatt ccgttcattt ccccaaagct gaacggtttg agctggaacg tttctatctt
    16381 cttcgcctgc agttgatcca ttattagtag catagtcgta atttcgccag ttcgctcccc
    16441 cgtttgtata atcactatca tcgatcaagt tctctccgtc atatggcgag cctttgtctc
    16501 cttgatagcg ttcattgctt tgtgtccaat ttcctaacac ttttgtatag tcattcgttg
    16561 taaacttcgg gtagcgatgc tgttcgtttt caacttctcc gctaggatag atatattcat
    16621 aggggtcttg cgtagctgtt ggcccaagac gctccaaaat accgttgaat aactggcgtt
    16681 gaatgcgctg gagtgcttga ccgctgggta cgattggttc gtccagcttt tccatctcat
    16741 tttcttcgct acgttgaatt tcagcggaat cttctgtatc agtttcattt tcttgtaatt
    16801 cttggttatc tattctttca tcaaccacca cttgaagagg tagttaccct tcgttcacat
    16861 cggggatctt ttctgtttca aaaatcaatg tgccggtttc tgcttctttt gaataaactt
    16921 ttccgacata ccattcttga ccatcgatcg tctcgacttt taggtcttct ccatcttcat
    16981 cataggagga tagacctgtt ccacgaacgt tttttacggt accaatcccg gcggctgccg
    17041 catcgattgc taaacgtatt ctaccttcat tggcactttc ctttttttca aaagccagat
    17101 gccattcaag ggtttcttct ttttcaatat acttcccttc aatttttgca tagtcctcat
    17161 ctaagaatac ctcatcctcc tttgtttctg ttgactcagc agctacatcc agggtcgtca
    17221 tatgatagac tgactggaaa tatggtccaa atagcaaact gacagttact aactgcaaaa
    17281 gcttcaattt taaccctttc acatccttat actcctttca aaaatatttg tcttctttca
    17341 caacaatcaa caaaacaatg cccatctaat tataatttaa tttaatttta attttaaatc
    17401 aaatgatatc ctttttagtt aaaaaacacc aattatacaa catttattat taaaattaaa
    17461 ttataaaatt ttataacgtt ctcatttaac aaaacttaag ttattaagac aaatgaataa
    17521 acaactacgc tttcctcgaa acaaaaaaat aaagcacaaa tgcgcattta cgcactcatg
    17581 ctttattcgt acaattaatt cagataacgg cagcgcatag gatgccaata acacttccta
    17641 aaatagctcc tcctaaaatg tcagtaggat aatgtaaaag taaaaaaatc ctcgaataag
    17701 cgatcaaaca agcaaataaa aaggctaata ttcctgcaac tggacttaat tcgaacaacg
    17761 cagctactga taaaaaggct agcgctgtat gtcctgaagg aaaagaagaa gtcttcggtt
    17821 tacttgtgta aaggacaagc cgacgatttt tttcataagg tcttttccgt cttgtcgttt
    17881 ttttgataaa aagcaaacca acaaaaaaat agatcaaact gccgataaga atggctagac
    17941 catattctct agtatcaggt atcaagacta aaacagcagc aaggagcaac caaataaaac
    18001 caccattaga gatattactg ataaatttca aaaaattgat ttttcgacta tccgttttcc
    18061 gttgcttggc gaacttgttg ataatactat catcgatttt agcaatcaaa cgcaacatgt
    18121 tattcctcct ttttaagaac cttttcttgc gtacgatgga taaaaagcag gacttgaaaa
    18181 taaaacaaga aactgaaacc taataaagca aaatagattg gtcctgcaaa ccagaatgcg
    18241 acaagaagga tcaacgtgcc tgccaaatag aaaagcgcgc ttttgaaatc attaaaaaac
    18301 aagaaaaatg cagtaatcca agaagcttct ttttgttcca gttgaagcaa gattttgtaa
    18361 ctaaagagaa gcgcgcttaa tagaagcaaa aacaacgtag tatacatcaa tgtatagcca
    18421 attcccccac cccaatagcg gaaaatctga taatcgatca atagaagaag aaaataaaca
    18481 cttgctaaac tatcttgctt tccataaaga gagaagttct cacgaaactt tttccagaat
    18541 agtgaaccga gctttttctc ttcatttttt ttgtaatgat aaatcatata cagaactgtt
    18601 cgacttgcag ttcctaatgt gaaaacaggc aagacgcaca ggaaccatag tagctgtaaa
    18661 tggataagac gtggaatcca ttcaatgatt tctaagaaat aatcattggc ttttttacca
    18721 atcgatcgat tcatcatcct tttgaacctc ctgtcaaatc catcccttca atgaaataac
    18781 gttgtgcaaa aaagaacagc aaaatcgtcg ggatcaagac aagtgttgct cctgccatca
    18841 gataattcca ttgtgtcgtt gcttggttct gaaaaacttg caagccaatc tgtaacgtgt
    18901 atttttcttg atcttggata tataacagag gacctaagaa atcattccaa gctgcgttga
    18961 aggaattgat cgcaatggta atcaaggcag gtttcgtcaa tggaagcatc aaatgactcc
    19021 aaatatacaa atgattcgct ccgtcgattt cagcagcttc gatcaattca ttattgatcg
    19081 ataagtaaaa ttgacgcatc agaaatatat tgaacgcatt gccgaagaac gatggaacga
    19141 tcaggggcaa ataagtacct acccagccga tcttggagaa taatacatat tgagggatca
    19201 tcgttacaaa ccccgggatc atcatcgtag aaagaaccaa agcaaacatc agctttttcc
    19261 caggaaaatc aagcttcgca aatccataag caataaaaga atttgaaagg acattaccga
    19321 tcactactag cacagtgatg aataatgtat ttcttgcata gcgccaaaaa ggaaaggcgg
    19381 caatcgtatc cagatagttt tcccatacga ttttttctgg gaaaaaggtc ggaggataac
    19441 gaacgatttc ttccattggt ttcaatgaag taaacaccat ccaaagcaat ggaatgatca
    19501 aaatgattcc tattactgtc atgaggacat aacttagtat tttttttgtt tgccgattca
    19561 cactggtctt tttgaaataa tccatcattt gccgtcacct ccagaataat agacccactt
    19621 aggtgcaagc ttcaaattga caaacgtcag aaccaacacg atcagaaaca ggatcattga
    19681 catagccatc gcataaccca tatcaaaagc tacgaacgcc ttgttccaca tatgcagatt
    19741 ataaaaaagc aaagaatttg caggtccgcc tgttccattt ttcgtcatga cataagcttc
    19801 ttgaaaaatt tggaaagaac cgatcgtaga ggtgatcaca tcgtaaaaaa taataggagt
    19861 gattaatggc aaagtaatac ttttgaactt tccccaaacg cctgctccat cgatttctgc
    19921 tgattcatat aaagatctag gaacattttg taatgtagct aagtaaagta gcattgctcc
    19981 tccagaactc catattttca tcaaaatcaa cgcaggtttc gtccattgtg gatcaaacag
    20041 ccaagctggt ccagggatat ggaaccagcc cagaaatgtg ttgatcaatc ctgcagatgg
    20101 agaaagcagc tgcatccata agatgtagac tgctactcct gataagactg ccggtaaata
    20161 gaaagctgta cggaatacac tgattccttt gattttttga ttgagtactg tggctaaaaa
    20221 cacactgaaa atcgtcgtca gcggtacatt gaagatgacg aaataaacgg tgttgtataa
    20281 cgatttccaa aataaatcat cgtgaacgaa cattcttttg aaatttgcta gaccaatgaa
    20341 attcatcttg gatgtcaaat tataatcggt gaaactacca ataactgaaa aaagcatagg
    20401 ccctagcata aataccaaga acccgataat aaaaggcgag ataaataaat aggcccatct
    20461 tgcttctttt ttctttcgga tagataaacg cttcaaattt tcttgcctcc tctgtaccta
    20521 gacagtcaaa aatggattat tgattttgct tgactaagtt ttctactgct ttttgtgcat
    20581 ctgccaatcc ttcttttggt gattttgttc ctaaaagaat ctggtcaatc tgttcattca
    20641 ctaatgtcgt gtaatccgga gcatctaaag gaactggtgt gatcaccgta tttttaaagt
    20701 tttcgtccgc catttgatag atcatttttc ctttatccgt taggttgtca ttattcacta
    20761 aattctcatt ggctgtcttg ctcgccatga tatcaaaact tttttcgccg aatttttctt
    20821 gtacttctgg agaagaaaga tatttgatga attcataaga ggcctcagga tcttttgctc
    20881 cgtatggtac ttccaagacg aatccgccac cccacgacca atggcctgaa ccttcttctt
    20941 tttctgggag ctgcatcacg ccaaaatcaa aatcatccgg tgcattttcc atcaaactag
    21001 agtaataatt gatattttgg gcacgcatgg ctactaatcc ggaaataaat ggatcagata
    21061 caccagaccc aaattcggct tctaatttat tgatcgtatt tttcccataa taatcttgcc
    21121 agtcttggat ccactccaag gcttccactt tatttttagt atcaatcttg actttttcat
    21181 ctttgtcaaa ccaactagtc ccgttatctg cgtttagcgc ccatacatca gcccctaaat
    21241 tccataatgg ataaaaaccg atgcgtgtaa attcttttcc ttctttttta tctagtttac
    21301 gtgctgtttc ttctaattca tcccaagttg tcggtagatc ttgttcactg attccagctt
    21361 ctttaaataa ctttttatta taaaaaatga cttgtgtatc tgtattgaat gggatcgcat
    21421 aaggatcacc ttcatattct actgtatccc aaagctgcgg ataaaaatcc ttagaagtgt
    21481 ctttttctac atatttggag agattagttg cttgctgtgc ttctgctctt tgggcaacgg
    21541 aatttatgtc ctgtacaata acatcgggtg catttccagc tgttattgca gataaagatt
    21601 tagtccagat gtcaccccat ggctgatact tataatttac atggatctcg ttttgtgatt
    21661 gattgaaatc ctcaatgatt tcttcgatag cttcttttcg tgcaccggat ccccaaaagg
    21721 accagaaatc aatatttttt cttccatcac ttgttttttc agaagaattt gctgcacttg
    21781 aactggcatc gcttgcatta cttgatccgc atcctcctaa taaaaacaat gctgaacttg
    21841 ccagcaaccc tgtaaacaat aattttttca tattttacct ccaaatttta atgtaaccga
    21901 tgccggtttt aatataacga tatcattttg ttctgaaaat aacaatttat aaggtatgat
    21961 tctaaaaaaa ttattaatga taccaatact ttatataatt cgcgagcgct ttctttgaat
    22021 tttttaatct ttcgtagcag aatgagaatg tattaaaaat agattaggag gaattttgat
    22081 gtttagacac cagaaagaat tgcagtttga agcaaaacca gatcgtccga atccattaat
    22141 cgcgaaatat ctgcaggagc tgatcggcgg ccaatatggc gagatgagtg tagctatgca
    22201 gtacctgttc caaggctgga gctgccgagg agaagaaaaa tataaagata tgctgatgga
    22261 cattgcaaca gaagaaatcg gccacgtgga aatgttggcg acaatggttg ctcgtttatt
    22321 agagggtgcg cctgttgaag atcaagaagc agcgatgcaa aaagatccaa caatcggtgc
    22381 cattatctct ggaatgaatc cacagcacgc gatcgtagct ggcttaggac ctcgtcctgc
    22441 tgacagcgtg ggcaatccat ggagcggtgc ctatatcatt gcgagtggca acttgttagc
    22501 agactttaga gctaatttaa atgccgaatc acaaggaaga cttcaagtag cacgtattta
    22561 cgaaatgatc gatgatcgtg gcgtaaaaga tatgctgtct gttctccttg caagagatag
    22621 ctatcatcaa aatctatggg aatgtgcagt gaaagaatta gaagaaaaag aaggttcaat
    22681 cttagtccca agtactttcc cgcgtgacaa agaacgaaaa gacattgctt atgacttcta
    22741 taacttctca gagggagacc aaagtagtga aggttcttgg gctagtggca aagcactgga
    22801 tggcgaaggc gaatatcaat ggttgaaaga acctaagatc gaaggcgctg caccaaaatt
    22861 agaaccagta acaccaaaaa tgtatgggac acctccattc aagaaataaa tatctacccg
    22921 tagaaacacc cgttttttgt tccacacgct ttgtgagcaa aactgactaa agtcattaat
    22981 cataaccacc cttcaaaagg gtggttttct ctagagctat aagctcaaat caccggccag
    23041 cgcctaaaga cgctggcttt catattttat gttcaagcca tattgccttt gccagttttg
    23101 cccacctctt aaaaggttta tgtactactc cttagccctt aaaaggatcg tcttactctc
    23161 gtacactcag cttatctaac gcactatcat gtttttcttg ttcttgaatg tactttttga
    23221 tggtcgcttc attttgtcct acttttgtca catagtatcc ttccacccaa aagtgtcgat
    23281 acccaaattt atattttaga tttgcacaat ctcttgatga tctcctgaat attggctcga
    23341 tattgattat aaattatttt tcttctatac tttggtgtga atacaatgtg gtatttacac
    23401 atctactttg tacgggctaa actatttccc tttattgctc cacccgcata gcaagtggtt
    23461 ttgtatttca atcgctcggc gcgctcaatt aggtctaaag acaataaatc taaaaacccg
    23521 ctgcttcact gacagaaaca acgggttttc agaaaaaaat gaaatgaaaa agatctctta
    23581 cggcaatcta ttttattttt ttgatttttt ataaatggaa aatgcttcaa gaagtccaag
    23641 aaataaagcc gtataaaaac aagaacctat gaaatcttta tttattagat attcaacaga
    23701 aatcccgata acactagcca acaatatatt tatcagaagt gtaaaataag gatgcttttt
    23761 atagaataga actagtgttg ttttcataga ctctcctttc ttcatatttc caattaatca
    23821 caaattcacg gcattactag aaaaattaaa ggggcgcaga agtggaaaaa tactcttcga
    23881 ctttccctac aaaccaggcc atcttgtgtt taataactat accaaatcta aggtacctct
    23941 aaatctaaat tccatttgtg gcggtgacct ccaattttta actcttctat ctcccatcca
    24001 gtatacataa ccttgatact tcgaccactt atatatcgaa cacacaaata cctatccatt
    24061 gcaggagtac tacctaactt agttgctact tgcatctaaa taacagctga aaagatagga
    24121 cttactctta gtaaagtatc tgaactatta atttttaaac tatcattttt atcctcaact
    24181 acatgcacat ctgttgcaac ttcactttct gtctcatcca gataaatgat taaggaatcg
    24241 ggaattgcaa tatcttcagc tgacgctgga atagttgagc taaattagtc atcatatctt
    24301 tattataaaa taaccaacag caaaaaatac aatgaaaaac aaacttggaa ctaatgtatc
    24361 attaataaat gttgaaaaat tcagcaactc attactgtat gattttagca gcccaaccaa
    24421 catataccct ataaaagcta ataagatggt taggaatcct ttagaatttt tactcattca
    24481 tagacacttc cttaaataac ttttattata gaaggtattg taaataataa tattgacaaa
    24541 aagtgactca aaataaaaaa aaccttacat tatactggaa tgaactgtat tgatagtgta
    24601 cctaaaagct ctactgacat aagatcgtgt aatcggtaaa gtaattttat taattatacg
    24661 ggatgtaatc aattagagaa taaactaatc ataaaaggta cttttacatt cataattgtc
    24721 gctttgagat tctactttgg ttcactatct gacccaattg cacattttcg atcattacaa
    24781 gtattggtgt cgttagaaca actaaataaa aactagcggt agatttttca gaatctatgc
    24841 taatttctgt atggatgttc cagtgatggc aaatttctct tttcattgtt tttcttgtcg
    24901 catgatatgc ctttttgtgt tattcagtta aactatagaa attctttcct agacagatct
    24961 tgatcccaaa ttttacgttt ttgagcatcg atatagttta aaatgacatt actcatatct
    25021 aaagagttta gattttttag gactaaaact gtcagttgtt ctttttcttc tttctgttaa
    25081 agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa gttttgtgac
    25141 acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat gctatatatt
    25201 ctttagttta agatacggaa attaatgcca tcgaccacac tagtagaatg aacgacattt
    25261 acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag agtttactta
    25321 caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt gcaatggtaa
    25381 gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt gtgtaataat
    25441 tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta aattctttat
    25501 agtggaagta attggacata tgaccgaaaa cattgtttta cggttaaatt cataacgaga
    25561 gacgactagt cctggtcgtc ttttttgaat ttcttttcct acggagggat caaaatcaat
    25621 ccatacaata tcaccttttt taggaatata aattctttct tctgacacta taaaatttct
    25681 ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc ctcttcccca
    25741 ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc agaatacaca
    25801 acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa agttaccact
    25861 acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc cttaataaaa
    25921 gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct agaaaattgt
    25981 tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca gttcattttt
    26041 tctttaacta aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa gctacccaaa
    26101 tactatagct aaccccccgc taccttcaat tttgcagata aaacgctttg ggagaaaatt
    26161 tcaaagacaa caggccatcc tatcatgccc gattataaac aaaaagctgg ctattccttt
    26221 tgctctgaca aatttcaatt gggaaagttc acgaaactag caggtgaaga agtttcaact
    26281 gttcggatca aagaatgccc gcttcaaata gaaacattgg ttcaacgaat ttcaactaga
    26341 caagactttg ctattgtaga acgtgagatc gtagctattt ttgtagaaga agggatttta
    26401 catgatccaa ctcatatcaa tgtggataaa tggcaacctc ttatctataa attcagagaa
    26461 tatacaactg ccaaccagtc gttaactttg aattttagat tccaagaatt caaagagtca
    26521 taatgataaa catcgttagg tataaataaa aaagactcgc agcacgagta aaaaacaaat
    26581 agaagctata cattagaaag gtcgactgtg accctataga tgcagtatat gcagcttatg
    26641 agcatttctt ctgttctctt tgtttttggg atctgtgctg aagtcttttt cgttttttgc
    26701 cgctctttct ttgaaaaatc gattatgtta taccttctcc attactaatt caggcatctg
    26761 ctgagtaatg atttttcgcg caaaagaaat atctgttacc caaggttcga tttgttcttc
    26821 agtcaagaca agcggcattc ggtcatggat tggtgcgact gtgcggttag gttcagtagt
    26881 cattatgatt gattctgcca ttttttcatc ctgatggcta cgataaaaac cgccaatata
    26941 cactattttt tccttatttg aaaacataaa tttgtctttt tcttcattcc actcattggg
    27001 aaaacacaac gattttgcaa aaatggttga tgaaaggtct ttttttcttc tactgtctct
    27061 gcacgggcat taatcatcaa ttgtcctttt ttaaatccgg taaatcccca cttcatgatt
    27121 tccggagtga ggatgttttc ttcctctttt cttaacgtca caacaagatt tgacggaaaa
    27181 acttctccag ctgctaattc tgctgcctgc ttcggttgtt tcgtctgggc ttctcgataa
    27241 taattctgaa ggagctctga ctctagatca aaaaaataac gaccacacat cctaatccct
    27301 cccaatcttt ttttctatca tacactgcaa caagaagttc gcaccaacaa aacgctttca
    27361 atttttgtag aactaaaaaa gttgtgacaa gtgacaaact ctccagtgaa tggtattctc
    27421 ctgccaactc ctcggtcaca agtcacaata ttcaacaaac atgagaagct gctttttgaa
    27481 attgttcctt gtgactcgga gtgaaacggc aggcttacga cctctgggta aacggtgttc
    27541 aaaagccagt ttctcggtat taagccaaat ttatgcaaaa atgtagaaag ctattttcac
    27601 aaaatttttc ttaatactcg aaactaagcg actttttcac aacctcttcc ttaaacggtg
    27661 ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatatga gcagctattt
    27721 ttatttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc tccactaaac
    27781 ggtgttcaat cagctaacct tcggtattag ctcaaaaaac ggcaaaatat gaggaactat
    27841 tttgccgttt gtttctctaa tactcaggtc aaagcgctga tttcacaacc tctaatacac
    27901 ggtgttccag aagtagcttc ttcgaaaaat aagccgaaat ttcacaaaaa tttgagaagc
    27961 aattttcgta aattccttct tatttcttga agctgaccac ttctgtcaca acctctaatt
    28021 attaaagaac cttttgcgaa gttaacaatc tttctttgat caattgaaaa ttctgcctaa
    28081 gtagtgatag atcctgtgtg actttcaaca ataagatact tccctggatt tcagcaatca
    28141 acgctttggc ttgacggtct gcttcttcat cggacagttt ttcttcagaa agtgccagga
    28201 tattttgttt cgtatacttg acccattgat tgactaattc tagtagcaac agacggtatt
    28261 cttcatccac tgtactcaac tcaataatca aattacctac aggacagcca tgataagtga
    28321 tctgtgtctc atgatcagcg aaaatccagt ccaacatttc ttctaatgct tcttctggct
    28381 gttttccagc atttaagatg tcttcgaaca attctgtctg ccatacgtcc atatgcgcat
    28441 ggatcaccgc tagacaaact tctttttttg aagaaaagta ataataaaat tgaccttttc
    28501 ctgtatcaga agctgctaga atatctcgga ttgacgtttc atgatagcct tttttataaa
    28561 taagatcttt ggtcgcttcc aagatctttt cctttgtttt caatgatatt ctcctttttc
    28621 atttctcata gtcctatatt atacagtaaa ttcatcattt tttcttctta atcgtttaaa
    28681 aaagactgtg ccaaattatc tgacacagcc ctcactataa aactgttctc atatagctag
    28741 atgttcattg attcaagaac tgcgaggaca aaagcaattc ctatcttatg atagttgctc
    28801 taatacttcc tctgttgtca tcacttgatc tgcaataaag ccaaagttcg tcaacgctgc
    28861 atccattgct tcttggccag gagcaccaat tgcatctgtc gctaccacaa cattgaatcc
    28921 actctctacc aattcacgca tatgggaatc gctacacaag tttccgttca ttccaccaag
    28981 aattactgtg tcgattccat tttttctcaa ttggagcgcc aaatcattgc tttctggtcc
    29041 aaagatttta tgaggagagc tgatgatcgt attttcatcc aaataaggtt tcaattcttc
    29101 gataaaatcg gctcctgaac cttcttccac tgattcatat tgactttttc tagcaaacat
    29161 ctgctgctca agcatcatat gttctcctgc accgccaaat tgccatttat ggtcatgtgg
    29221 gtaaaaataa tgaggagaaa taaagagttt gtatcctttt tcttttgctt gttttaccat
    29281 ttcaatcata ttttcgatcg tattgtattt ttctaagata tcttttgtca aaccaaagcc
    29341 accgcctgct ggtttcaaga actcgacttg cgggtcagtg agaactactg ctgtattttt
    29401 attattgaac atggtggatt ctccattcgt tatttatttt aatacatcat ttagagcttc
    29461 actcattgtc ggatgagaat agatttgatc tctcaataac gtataaggaa gttttccatt
    29521 catagctagc gaaatcaagt tgatgacttc atgagaatct tccgcataga tacttgcccc
    29581 tagaatcaag tcagtttcag ggtcgactaa aactttgaat acacctttag gatcttctaa
    29641 tacttgtgct ttagggacac cgcttgtcat atacttgaat aatttgtaat tgacgccttg
    29701 tgctttggct tgtttttctg ttaaacctac attggataaa gtcggagtga taaatacact
    29761 gtaaggcaca gctttccggt tattcgttgt tcgtttattc tcgcccttca actgatccat
    29821 aatgattcga taatcatcta gagagatata agtgaactgc aatccgcctt tgacgtctcc
    29881 aatcgcccaa atgttgtctg catctgtacg aaggtattca tccacagcga ttgctccgcg
    29941 atctgttagt ttaacatctg tattttctaa tccaagtgat gctgtacttg gttttcttcc
    30001 agttgcagcc aaaacttttg acgcttggat tgttacttct tggccatctt ctgtaaaggt
    30061 gacggcagct gttgattctt ggtctgctac ttgatctaca gatacaccta gatggaattc
    30121 gattcccgca tttgtcatgt cttctaaaat catttgcgcg atatcttcat cttcacgtgg
    30181 aagaaattca gaatgggcat caagaacgac aactttagat ccgtattcat tgaacattga
    30241 tgcaaattcc aagccaatat atccagcccc gatgatcact aatttttccg gtaattgttc
    30301 ctgatccatc gcttgcgtag aatcaatcaa gtagcgactt gtattcaatc ctttgattgg
    30361 taaaatgatt ggttcagaac cagtattgat gaaaatccgt tcgccttcaa caatcacttt
    30421 ttcaccatta ttcgtcactt cgatttgatg gttagaaaga aaacgtgctg taccgtccat
    30481 cactgtccca gttgcctcat cgctgatcat atgataattt ttggcgcgaa gcatgcccgt
    30541 caatttttct ttccgagcaa cagcctctgt aaagtcgatt cctctttctc cattgaaaat
    30601 caatgattta gaaggaatac agccgatgtt gatacatgtt ccgccataca tacgtgttga
    30661 cttttcaacg actaaaaccg attcaccttt tgaagctaac gccttcgcta aagtcttacc
    30721 gccctttcca aaaccgatca caatattttg atatttttcc atcatttttc cctcgcttct
    30781 tttttaccta ccgattggta caaaaatatg ataaccgata attgtctatt ctccaaatca
    30841 tctgctttat
//
LOCUS       DAIGUC010000035        29682 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.035, whole genome shotgun sequence.
ACCESSION   DAIGUC010000035 DAIGUC010000000
VERSION     DAIGUC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.035"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..116
                     /locus_tag="NOB46_001681"
     CDS             <1..116
                     /locus_tag="NOB46_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI1058615.1"
                     /translation="LSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            308..928
                     /locus_tag="NOB46_001682"
     CDS             308..928
                     /locus_tag="NOB46_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCI1058616.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(1020..2186)
                     /locus_tag="NOB46_001683"
     CDS             complement(1020..2186)
                     /locus_tag="NOB46_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1058617.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(2198..2551)
                     /locus_tag="NOB46_001684"
     CDS             complement(2198..2551)
                     /locus_tag="NOB46_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI1058618.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            2679..3701
                     /locus_tag="NOB46_001685"
     CDS             2679..3701
                     /locus_tag="NOB46_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HCI1058619.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            3720..3881
                     /locus_tag="NOB46_001686"
     CDS             3720..3881
                     /locus_tag="NOB46_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058620.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(4140..4574)
                     /locus_tag="NOB46_001687"
     CDS             complement(4140..4574)
                     /locus_tag="NOB46_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058621.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(4684..6543)
                     /locus_tag="NOB46_001688"
     CDS             complement(4684..6543)
                     /locus_tag="NOB46_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI1058622.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(6661..7820)
                     /locus_tag="NOB46_001689"
                     /pseudo
     CDS             complement(6661..7820)
                     /locus_tag="NOB46_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(8127..9551)
                     /gene="araA"
                     /locus_tag="NOB46_001690"
     CDS             complement(8127..9551)
                     /gene="araA"
                     /locus_tag="NOB46_001690"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCI1058623.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(9567..10265)
                     /locus_tag="NOB46_001691"
     CDS             complement(9567..10265)
                     /locus_tag="NOB46_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI1058624.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(10222..11883)
                     /locus_tag="NOB46_001692"
     CDS             complement(10222..11883)
                     /locus_tag="NOB46_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HCI1058625.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            12101..13501
                     /locus_tag="NOB46_001693"
     CDS             12101..13501
                     /locus_tag="NOB46_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HCI1058626.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(13753..14832)
                     /locus_tag="NOB46_001694"
     CDS             complement(13753..14832)
                     /locus_tag="NOB46_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1058627.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(14918..15877)
                     /locus_tag="NOB46_001695"
     CDS             complement(14918..15877)
                     /locus_tag="NOB46_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI1058628.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(15889..17400)
                     /locus_tag="NOB46_001696"
     CDS             complement(15889..17400)
                     /locus_tag="NOB46_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI1058629.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(17422..17985)
                     /locus_tag="NOB46_001697"
     CDS             complement(17422..17985)
                     /locus_tag="NOB46_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI1058630.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(17991..18854)
                     /locus_tag="NOB46_001698"
     CDS             complement(17991..18854)
                     /locus_tag="NOB46_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058631.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(18868..19764)
                     /locus_tag="NOB46_001699"
     CDS             complement(18868..19764)
                     /locus_tag="NOB46_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1058632.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(19939..21228)
                     /locus_tag="NOB46_001700"
     CDS             complement(19939..21228)
                     /locus_tag="NOB46_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1058633.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(21200..22717)
                     /locus_tag="NOB46_001701"
     CDS             complement(21200..22717)
                     /locus_tag="NOB46_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI1058634.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            22915..23805
                     /locus_tag="NOB46_001702"
     CDS             22915..23805
                     /locus_tag="NOB46_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HCI1058635.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(23878..24702)
                     /gene="nadE"
                     /locus_tag="NOB46_001703"
     CDS             complement(23878..24702)
                     /gene="nadE"
                     /locus_tag="NOB46_001703"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCI1058636.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(24714..26186)
                     /locus_tag="NOB46_001704"
     CDS             complement(24714..26186)
                     /locus_tag="NOB46_001704"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCI1058637.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(26823..27185)
                     /locus_tag="NOB46_001705"
     CDS             complement(26823..27185)
                     /locus_tag="NOB46_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI1058638.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            27408..28160
                     /locus_tag="NOB46_001706"
     CDS             27408..28160
                     /locus_tag="NOB46_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1058639.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(28300..29223)
                     /locus_tag="NOB46_001707"
     CDS             complement(28300..29223)
                     /locus_tag="NOB46_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1058640.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFSFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(29238..29510)
                     /locus_tag="NOB46_001708"
     CDS             complement(29238..29510)
                     /locus_tag="NOB46_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058641.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8803 a         6160 c         5084 g         9635 t
ORIGIN      
        1 ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact gctaatggtt
       61 ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt gcttgaatat
      121 tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc ttttataccc
      181 tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag ccttttcttt
      241 ttcgagtaaa ctgattttgt tagtcatagt tataacaatc atagcaataa aaggagaagg
      301 taagcatatg gcatctgttt tagtagtcaa aggtcatccc ctaactgcag aagaatcgcg
      361 cacagttaag gcattgacgt cttttttaac aagttataaa gaaaatcatc cagatgatga
      421 agtgactgtt ttggaacttt atcgcgatga tattccggaa atcgatgaag aattattatc
      481 aggttgggaa gcattacgtg ctggtgcaga attcacttcc ttatcagaaa gtcaacaaca
      541 aaaaattgct cgtttcaatg aattgactga tcagttcctt gctgctgata aaatcgttat
      601 cgcaaacgcc ttatggaatc taaatatccc aacaaaatta aaagcttggt tcgataccgt
      661 caatgtagct ggaaaaacgt tccgctatac agaaaacggg ccagaaggat tagtgacagg
      721 taaaaaagca ctgcacatcc aatctaatgg cggtgtatac aacggacaag actttgcctc
      781 tcaatatgta aaaggtattt taaactttgt aggcatcgat caagtagatc agctattcat
      841 cgaaggaatc gattatgacc ctgaccgtgc agatgagttg atgcaaaatg cattagataa
      901 agctgctgct ttaggtaaat cattttaaaa attgagataa atgcatacaa aagagacaga
      961 ggaaaaaatc ttcaaagcag catttgtgcc ttggatattt tcccatctgt ctctttttgt
     1021 tattctttct gctttttcaa cggattttct tcataaagag aagagattgt tgtgtaccat
     1081 tcaaaaacat gagtaatcac tactttagct gctgcataaa caggaatccc caagatcaca
     1141 ccgatgattc cgaacaattt cccagaagtc agcagaacta ataaaatcgt tactggatgg
     1201 attgctaact gattccctag tactaatgga gagatcaagc gtccttctat tgtctgctct
     1261 actgcaaaaa cgatcagtac tttgatgatc atgaatggac ctgctacaat ggctaaaaag
     1321 atagccggaa tcatcgctaa aaatgatcct aagtaaggga tcaggtttaa aaaacccgca
     1381 ataatcccca acgtgacagc atactctaaa ccaatgaccg caaaaccaat cataaacatg
     1441 attgccacag caaaagccac agttagttgt cctcttatat aagaagaaac ttgactattc
     1501 atttcactca gcacattcaa cgtcggtttt tgcatgcgtg tcggtaaaaa tttgacaaaa
     1561 taaggtgcta attgtttacc gtctttcaat agataaaata agataaacgg catcgtcagc
     1621 agagccacta aaatagtcgc taccgcgccg acaaaacttc caagactctg aactgtactc
     1681 ttagatatat cttggatcat atcgcctgcc gaattcatga acttatcacc tgctgtttcc
     1741 aactgttcgc gaaattggtt gaacagcggg tcccgcaaaa tctcggttaa tttattatca
     1801 atcgtatcta catattgagg gaagttactg atgaagctca ctgtttgttc ctgaatctta
     1861 gggatgatca ctacgctccc ccatgcgatt agtgcaacaa ccaaaacaaa cagcccaatg
     1921 atactgtaaa gccttggtac ttttcgcttt tcaaagtaat caactaccgg attcatcaag
     1981 taatacaaga ttcctgctaa aatgataggc agacctacga ttgctaaaaa ttgccagatt
     2041 ggtgcaaaca aatatgaaac ttttgtaaat aaaaagacga tcagcaatat taacaataca
     2101 acaagtaagg ctgtgactac ttgattattt aaaaaccagc gccaaaacca cgataccggt
     2161 ctgttcttct tattttttcc ttccataatt cctcctgtta gttataaaaa atttggcttc
     2221 ccaaaccaat agcaggcagt ctatgcggat gaagatagat tccatttgca atttgtcctt
     2281 cttctggaca agcatcaaaa atcaatgata cgtgagctac tgtctttaaa ttcccattgg
     2341 ccatcggacc gacataatcg atcgtatata cctgatcatc aaaagcaatt gttccgcctg
     2401 ctttcaaaga aaaaggttcg tcttttgata cttcttgaat caccgaatat tttcgtaagg
     2461 cagctgttgc tgttttatcg aacaaaatca gcatgggttc ttccttgttt attgcttctg
     2521 tcccaatttc tgtaatcttt gcctgaatca ttgcactctc tcctttaatt gctttcaaaa
     2581 acagtataac acattctcat tctttagccg tgtggaataa ttatgtgata gaataaaaac
     2641 gaaaactatt tcattacaat taggaggaat cagctcatat gatcgaaaag ataattttag
     2701 gaacctatac gcgtcgcgaa agtaaaggaa tctatacgat cgaccttgat acagaaaaag
     2761 aagaattagc caacctttca ttagctgttg aagaaaatag ccctacctat gtagcaaaaa
     2821 gtaaagctgg caatctttac acagttacta gtgtggatgg attaggtggt gccggtgcgt
     2881 acgataagga ttttcatttt ttgaatgcgg taacagagtc tggcgctcct ttgtgttatg
     2941 tagcggttga tgaagcacgt caattactat acggggcgaa ctatcataaa ggtgaagtaa
     3001 atgtctacca tatattagga gatggcgaac tgaaagcagc agattcaata ttccatcaag
     3061 aagcgacagg tcctcataaa aaccaagatc atgcgcatgt ccactatacg gatctgactc
     3121 ctgaccaacg attagtcgta tgtgatcttg gtacagatcg tgtgtatact tatgatgtgt
     3181 ccgaaaacgg caaattgaat cttgtaacta ccttcactgc agagccagga acaggccctc
     3241 gccatcttgt ctttcatcca aatggacaat tcgcttattt atttggtgaa ttagacagca
     3301 cagtccgcgt gctttcttat aataaagaaa caggtgcttt tgaagaatta cagaaaatat
     3361 cgaccttgcc agaagaattc gacggtgaaa atggaggggc agctatccgc atttcaaatg
     3421 atggcaagtt cctttatgct tctaaccgag gacataactc gattgctgta ttcgcagttt
     3481 ttgaagatgg ttcccacatt caaaacaagc aaatcatctc aacagaaggg gattttcccc
     3541 gcgatttcgc actagatcca agcaataatt ttgtcgtgtg tgccaatcag aacaccgata
     3601 atctgacatt atatcgccgt catcctgaaa caggattact ggaattactg aaaaaagatg
     3661 tctatgtacc agaatgtgtc tgtgtttatt ttgatcgtta gtaagaaaag gagaatgaaa
     3721 tgaatcagca agacgtatta gacagactac gggaagaact aaatattcct ttctttgatg
     3781 ggaaaatcga agataaagag tatagcgaag aggaatatca gaaactcaaa gccgatttac
     3841 agaactactt tgaacaatat gtacagaatg tagaaaacta atcagctttc catactatct
     3901 gaaaagaaca tcaggacaag acttttccgt ctatcctgat gttcttttct acaaataaaa
     3961 aaccgccgag atggttagac tcgacggaaa aggagtattt actcgatttt gagtaagtac
     4021 aaggttgttg ttggttatag gtatgtcatt atcataaagg attttgatca ctctatcata
     4081 aaggtaatat tacatttata ttagataact ctagttttta ttgttatcaa agatttcttt
     4141 tattttttca acaacaaatt agtcattttt tggatggcag ctgtcaattg gtctgtcgct
     4201 tggtcttgtt ttgcttcaga tgtattgaat agatcttcat ctacccctga ttcaagatcg
     4261 atactttgga tcatttcttc acagcctgct acatatgaaa gataagcttt ttcaaaattt
     4321 ttatgaatgc ccattgcttt tgctggtgga cgcaaagtac tgactttcat aagcattgcc
     4381 cgatattttt ttgttccttc ttcaaataac aggatgatct cttcaagagt cgatttgtcc
     4441 agttcacttg tttttccttc atcaattgcg tttctgatca cttcatattt cggatgcatt
     4501 ccttctccga ttgcttctgt ttccttgacg atttgatcga tggactgcac ataatagcca
     4561 atattcggta acatgttcgt tttcctactt tctccattgt tgttattatt tattctactt
     4621 gtttttatcc tcaaatgaca agtacttgaa aaaatttaat ggtttctata cagctcgcca
     4681 ttcttattcg tgctcaaaga aaccatctgc taaactatat tgtttccctg cgacaatgtc
     4741 atattggatc aattgatatt cgtcgtaaat ctcttgttgc gagcgattga attgcgcttc
     4801 tttataccac tgtccgtttt gatagtacag ttctcgttca aacgccggaa gttcctgttc
     4861 taatgataaa agcagctgat aaaagccatt tgttgtctga ttcgtctgtt ccattagatt
     4921 cgctgcaaaa taaaacggac tggtgattgc atcgtgagtc gtttgctttt ctaattctcc
     4981 tttactgtcg aacataagaa attgtgtttc atgcaatgtt tgtttgtcat tttttgcttg
     5041 gatcgtatct gaatagatcc ctggaagatg atccccccaa aaaacaacta aagtccttct
     5101 agaaagattc ttcaattctt ccgtgaactg cttcagtgcc gtgctgctat aggaaatatc
     5161 ttgcagataa ttctctaagt caagtgtccc acttccatct gaagtttttg caggatagtc
     5221 tagattatca tactttccat cgtagggcat atgtgtctgc atcgtgacta aatgaatgaa
     5281 ctgaggtgtt ttttcttcct tgagaagtgt cattacttct ttgtaagctg actcatcaga
     5341 aatatatgga ttattctcta tcgtatccgt ataggtcatc gtacgctcgc tgatgaactg
     5401 gtcaaatcct aatgtctgat aaacatcctc tcttttatac atcgaagtat tgtatggatg
     5461 gatcgctgtc gtctggtatg attgtgcgtt taacgctgaa acgatagaag gaagctgatc
     5521 catttttggt acaagcatcg tgtaaggggt ggtgagttgc gcattaaata acgccataga
     5581 aaaaccagtc aatgcttcaa attcgatatt tgctgttcca ccgccatagt tttgagaaag
     5641 catattgcca ctatatgttt gatcagctac ttcataataa tctgccaatg gctcaccaga
     5701 tacttctacg ccgtttaatc gactaggatc tgagaaactt tcactcatca cgaacacgat
     5761 gttcggcgac tcttcctcta cagttttatt tttttcatcg gctagcttct ggtatttttc
     5821 agtgatttct ttgatctttt ctttcgaata tccttcaggt tcatccattg gttctacctt
     5881 cagattgtac aaaaacccac cgataaaacc agtgttatag tagttcattt tctggctgta
     5941 aggtatccat agtgccgttt tattatatgc ttttcgcaac aaattatcgg gattgttgaa
     6001 attactgata taccctagca gtccaattgc cacaagcagt gtcgttaatc ggatcaattg
     6061 gaatcgcctt ccttttttca ggcttcgaaa catgtaccag caaaacaatc ctatcacggt
     6121 tcctgcggca gctaagatca ctgtaaacag catagtgccg gtcatatctt tcagcaatcc
     6181 gatttcagtg atcatcttca aatcgtctgg ataaatcggt tcttgccgat aactcatttt
     6241 catataattt gcaaaaccta atacaccgat ggctacgaca tacgtaaggg aacctaaagg
     6301 gacagatcct gctagtgcaa tcagaaaaat aagaataatc agcaagacga gacaggctaa
     6361 gaagaatttt tccgtatgcc aagaaaaagc aaatttcaac gcaaggtcta cggatagatc
     6421 attttgacac cactgcaaaa ataaattact aaaaacaaca agaaaaaaga tactgatgat
     6481 tgctgctgtt ccttttaaaa tctttttctg tttggtcgaa agtctgctta tatatctttt
     6541 caaatgcttg ctccttcatt tctatcaata aaagaatgtt gcttctctta ttttagttgt
     6601 acgaaattcg aaagtaaaga acggaaagaa gaattaatga aatccaaata ttctctttct
     6661 ttatggcctt tctggtttct ttaataagcg gacctttcgt actccagaaa ttttttctag
     6721 ctgttgtttc acttgattga gctgttcaaa atcagtactg tctatgtcaa tcaatatgta
     6781 gacatgctca ttcttatggt tacgcgatat atctgcgatc gctagctcgt tctcattcag
     6841 cagagaaaat atctctgcta atatattggt tttcttttga taaaatatag tgaatcgaaa
     6901 cggcgcttgg aaaaacattc gtgcggatgg ataattgacc gcttctctaa ccgtaccgaa
     6961 caaaagataa tcttttaagg cttcaactgc caaacgtccg ctgtctgcca aagcttcctg
     7021 agtcgatccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
     7081 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
     7141 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
     7201 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
     7261 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
     7321 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
     7381 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
     7441 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
     7501 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
     7561 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
     7621 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
     7681 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
     7741 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
     7801 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
     7861 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
     7921 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
     7981 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
     8041 agactaaatt tcaaaaaagt tgaaaagcaa atatcgtcaa tctcttctta tttcttaaaa
     8101 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
     8161 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
     8221 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
     8281 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
     8341 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
     8401 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
     8461 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
     8521 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
     8581 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
     8641 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
     8701 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
     8761 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
     8821 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
     8881 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
     8941 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
     9001 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
     9061 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
     9121 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
     9181 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
     9241 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
     9301 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
     9361 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
     9421 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
     9481 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
     9541 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
     9601 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
     9661 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
     9721 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
     9781 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
     9841 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
     9901 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
     9961 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    10021 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    10081 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    10141 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    10201 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    10261 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    10321 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    10381 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    10441 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    10501 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    10561 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    10621 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    10681 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    10741 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    10801 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    10861 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    10921 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    10981 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    11041 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    11101 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    11161 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    11221 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    11281 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    11341 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    11401 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    11461 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    11521 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    11581 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    11641 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    11701 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    11761 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    11821 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    11881 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    11941 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    12001 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    12061 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    12121 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    12181 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    12241 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    12301 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    12361 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    12421 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    12481 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    12541 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    12601 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    12661 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    12721 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    12781 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    12841 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    12901 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    12961 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    13021 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    13081 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    13141 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    13201 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    13261 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    13321 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    13381 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    13441 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    13501 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    13561 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    13621 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    13681 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    13741 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    13801 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    13861 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    13921 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    13981 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    14041 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    14101 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    14161 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    14221 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    14281 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    14341 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    14401 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    14461 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    14521 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    14581 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    14641 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    14701 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    14761 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    14821 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    14881 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    14941 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    15001 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    15061 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    15121 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    15181 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    15241 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    15301 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    15361 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    15421 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    15481 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    15541 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    15601 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    15661 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    15721 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    15781 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    15841 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    15901 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    15961 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    16021 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    16081 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    16141 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    16201 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    16261 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    16321 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    16381 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    16441 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    16501 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    16561 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    16621 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    16681 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    16741 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    16801 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    16861 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    16921 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    16981 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    17041 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    17101 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    17161 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    17221 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    17281 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    17341 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    17401 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    17461 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    17521 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    17581 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    17641 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    17701 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    17761 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    17821 tcctgatccc tcacctttcc attgcgccat tacataaaaa acagcacatg tagcaggcac
    17881 gatagtaata acaggcaaac acacgattac ccagagaata cctaataaga tgtaatcaga
    17941 aaccacaatc aactgtccat aaagtttagt ctcaactatt ttcatcttcc tcactctttc
    18001 attccagaca tagctgttcc ttgaacaaaa tatttctgtg caaaaatata aaccactagt
    18061 aatggcagca ttgaaataac cgttccagcc attacaggtc cataaaaaga aatgttctgc
    18121 cctgtaaata aagctaaccc tgctggtaaa gttctcattt ttgaactact tgtcaatatc
    18181 aatggataaa gcaagtcatt ccaactattc atcagcgtga aaatccctaa tgataaaaga
    18241 gtaggtttgc tcaatggcaa catgattttc aaaaaaatat taaactcact taatccatca
    18301 atgcgtgctg cctcttccaa agaatctggt aaagtaataa aaaaggaacg catcatgaag
    18361 ataccaaatg cagttgtcat acgaggaatg atcaaacctg cataagtatc aagcatgcca
    18421 agcaaattga cttcaataaa tagaggaatc atgaagactt ggaatgggat catcattgtc
    18481 agcaaaacga aatagaacaa aactgatttt cctttgaaac gcatacgagc aaatgcatac
    18541 cccgcaagag aatcaaagaa tacagaagtg atcactgtcc ctccagcaaa aatcactgta
    18601 tttttgatgt aatctaataa agggatcgtt gtccaaacct taatatagtt atctagggta
    18661 tagctatctg caaatattct aggcggaaat gagataatgt ctttttcgtg tttaaaagaa
    18721 gaaataatca gccacaaaaa aggaaacgca ataaccaaca atataactag catactaatc
    18781 gttcgaatga tttttttacc actaactgct tttcgactat tcacagtaac tgtaatcgag
    18841 ctttctggtg ccatacaggt ttccctccta tttcatttgt ttttctttcc gtgacatgta
    18901 cacattagtg gagatagcta tagttgcaac aatgataaac aaaaccgaag acagtgctga
    18961 tgcatagccc aattcataag gtgctgtaaa tcctcgactg taaatatatt gaacagctgt
    19021 ttctgtctta aattgtgggc caccagcggt tgcaacatat acttggtcaa acacttgcat
    19081 cgaaccaatc agattcgtta aaatacaaaa acctaaggag ggaacgatct gaggtagcgt
    19141 aatgttaaaa aactgctgtc gatttgttgc accatccatt tgagcagatt catacaaaga
    19201 gggagagatt ccctgaatag cagtcaagag aatcgtcata gtaacaccaa aattcttcca
    19261 aacagtcatg atggctaccg tcggcatagc aagggttgga tcgcgaaaaa attgagggat
    19321 cggcaagccg acttgtgaaa acaagtaagg aatcgcccct acattcggat caagcaacat
    19381 agaaaaaata atcgcaattg acgtcaatga acaaataact ggaatgtaaa atgtcgaacg
    19441 acaaaaacga ttgaatctgg tatttttaga taatgctact gctgctaata aaccaacgat
    19501 aatttgtgtt ggcgtttcga gtacggtgaa atataaagaa tgaatcaacg aattaactgc
    19561 tcgttcatca ctaaatatac gtgtgaaatt ttcaaaactt acaaaatttc ttgatgtaaa
    19621 gaaaatattc aaatctgtaa aactaatagc aaatgttcct aaaagcggta tgacagtaaa
    19681 taataataaa actaaaaaag atggagttaa aaacaaatac gcagcacgat caggacgatt
    19741 ccaatatttg gtgaatccgt tcatatagtc cacctcatct ttcattttga taaaatatac
    19801 aatcttggtt taaacgaatc tgaataagat atccgaacaa tcgctgtgat ttttgcaata
    19861 acacctatct gcaaatacta ggtcgatcat tcagatatct gtatcttgcc aacagtctat
    19921 cctgtataaa gttctgtact atttttgcag taattgattg atggcatcat ctgcatcgtt
    19981 catgagtgtc tcaggatctt ctcctgctaa taatttttca atcagtggat tgatgatatc
    20041 gttattgatc gcagagattt gggtaaaacc tggtaaatat ggctctgcat agtccatttg
    20101 tttcgataat tcagatacaa taggatcatt ttttacttct tcatcttttg ctactgaatc
    20161 caagtaggca ggaaaaccat tttcgatact ccatttttta ccaatttcag ttgtattcca
    20221 atatttcaaa aactcataga cagcttcttt tttattatta tctgtacttg ccggaatggc
    20281 atatcctacg ccatctaaaa tagctgtttt tttgtctgaa tcactccctt gtggtaaggt
    20341 agtcacatta taatcaatct cgtttgcttt caatccgtta tttaaccatg gcccattgat
    20401 ttcaatggct agttgaccag cattcattaa attgtccatt tcggcgccag aaatcgattc
    20461 tggaccagtc ttgtctacat ggatcatttt ttggatcgct tttaacgttt taaggttctc
    20521 aggagacgca aattcagact tagtataatc atcgttcact aatttaccgc catttgctaa
    20581 catccagtta tataacggtg cagttccatc cttattgaag acaaaacctg atacattttt
    20641 actactatca gttaattttg gtgccatttc tgtcaattct tcccaagtag taggtggttg
    20701 ttcagtatct aatccagctt gtttaaacaa atcattattc caatacatat acatgccttg
    20761 tacctgcatg gggacaaaat actgtttacc ttctacttca cctaattcaa tagccgtttc
    20821 tttaaaatca gatttatcta ctccatcata ttcccagaaa tcgtctaatg gttgtaccgc
    20881 tccgttttct acatactgtg caaaatctgg ataatttaat gcaataaagt caggtgcttt
    20941 tttagaagaa atcgctgtag gaagtttttc attcaaattg gcccaagtca tgatatccat
    21001 ttcaattttg atgtttttat catttgtttt attaaattca ttaacgattt cttgcaatat
    21061 ttcaccatca gatgcagtaa acccattcca aaaagtcaaa gtcacttctt tatcagaatc
    21121 agattctgct gaacttccgc caccgcaagc tcctaaaata cctgttgcag ctaccaacaa
    21181 agagccaatt aaccattttt tacctttcat tttttgttcc tccttcatct gataaacgac
    21241 atctgaccac attccaagat agcggtttca ataaacaatt gattttccca tcttcagctt
    21301 ttacatttgt tgaatgactt ggttttactt gttcactttt aggaagatta gttgcttttg
    21361 tatcaaatcc actcatttca gaaaaatcaa tcactccctc taatgataat tcagacaagt
    21421 gaacagttag attcatttct tcttctccac ggttaactgc aaatatgaca agttctttgt
    21481 catttattac ggctatactt tctaaatacg gcacttcttc aaaatcttcc gtcgcatagt
    21541 ttgctgaacg aatttgtggg cttaacacct ctccttgtcc atacacagca gcttgcataa
    21601 atggataata gatcgtctgt ctccaagctt ctccgtttgt ttctgtcctg attggtgcaa
    21661 taacatttac caattgagca agacaagcaa tctttactct atctgcatgt ttcaataaag
    21721 tgattaatag acagcctaat agtaatgcat cttcaaaatt atagttatct tctagtaaag
    21781 gaggagcaat ctgccaaggc gctgcttgct catcttgttc cgctgaatga taccaaatat
    21841 tccattcatc aaaggacagg ttgatctgct tcttactatg tttcttcgcc ttgactgtat
    21901 cgcacatcgc tgtcacttca gaaatgaacc gatccatgtc taaggaacgt gcaagataat
    21961 gagaaagatc atttttttgg ttgccataat attgatgcag agacaaataa tctatttgat
    22021 cgtacgcttg atcaagaact gttaactccc aatcaccaaa tgtaggcatt tgccgattcg
    22081 aacttccgca taaaaccacc tcaattgaat catctacgag tttcatcgcc ttagccgttt
    22141 cctctgctaa ccgtccatat tcttccgctg ttttatgtcc aatctgccaa ggaccgtcca
    22201 tttcattccc taaacaccat gtcttaattc caaaagggct ctcttgacca ttcgaacgcc
    22261 ttaaatcact ccaataagtt cctttaggaa aattacaata ttcgactaaa ttacgagctg
    22321 catctactcc acgagtaccc agattgacag ccatattgat ttcggccccc acatgctgac
    22381 accagttata aaattcatga atcccaactt cattcgtttc aattgtccgc caagctaaat
    22441 ccaaccttct aggtctattt gctatgggcc caatactgtc ttcccaacga aatcctgaca
    22501 caaaatttcc accaggatat ctaatcatgg gaatgttcaa ttcttttacc aagtgaatga
    22561 cgtcttggcg aaatccactt ttattagctg atggatgatc tggctgataa atcccttcat
    22621 atactgctcg tcccatatgt tcaataaatg aactgtacaa ccgcggatca actttgccta
    22681 cacgcttgac actactaatc aacattgtgg cttccataac tgacctcctt taatttatac
    22741 atgaataata cacctcgttg aaagcgttgt caataatata aatgttaaac ttacttattt
    22801 tttatcgatt ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac
    22861 ttttattaac aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa
    22921 ctacaaataa acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc
    22981 aagatcatcc agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt
    23041 ggagtgagca gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc
    23101 aaaacagaaa aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatc
    23161 agttttccag aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt
    23221 cactatacaa attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc
    23281 gggaaagtgg atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc
    23341 tggtttacca gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca
    23401 ttggagatgt tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat
    23461 tggccttcag atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct
    23521 ggagattttg ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat
    23581 caatacggct tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa
    23641 cccttgtcaa acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga
    23701 atcgaagtga aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc
    23761 ggtaattacg atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta
    23821 ttttataaaa caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta
    23881 tttccagaaa tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca
    23941 ccatgcttcg attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc
    24001 aatttcatta tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc
    24061 aagatctgca gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa
    24121 ttgtttccct tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc
    24181 aaatttcgtg aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc
    24241 tgctctttct ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc
    24301 tttgttaaaa tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac
    24361 agctggtttg atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt
    24421 tgcatcttct tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt
    24481 ttcatctttt gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa
    24541 agtagaatct tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt
    24601 caaatatgct ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg
    24661 tttgacacct aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct
    24721 tctgtatgaa gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc
    24781 cagcattcag tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct
    24841 tcccatagtg aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat
    24901 tcgtaaactc tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct
    24961 cgaacagttt tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct
    25021 cgagggtctt catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga
    25081 gtgatgcgcc acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac
    25141 ttgatcgtat ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca
    25201 ccaagggctg gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt
    25261 ttagcttttt gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag
    25321 atttttgctt ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag
    25381 gccatatctc cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc
    25441 gccacgcgaa tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac
    25501 acgcagtctt tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat
    25561 tggactaacg aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt
    25621 acattgcttg ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca
    25681 tccagttctt gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat
    25741 ttgatacgag ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct
    25801 gtttctacta attggcagtg cgctaaaggc ccttccactt ggattaatgg ttcatttgca
    25861 aaaactagtt ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa
    25921 tactccaaaa aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca
    25981 ttgaacgtca gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat
    26041 ccgtggttaa aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga
    26101 cctaattccc agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa
    26161 ctgtcgtctg ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc
    26221 tacccattat aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc
    26281 acatgtttta cggatatttc ttgctaaaaa tgaactccat ctgctaaaac tatcctttct
    26341 tattggtatt taacctaaac gagaaagaat acttatttta ttcaatgtat ccgagacacg
    26401 aagaaattag cgttttctat ttttcttact tgataaaata agtagatttt cctactacaa
    26461 tcgtagccgt taagataccg atgattgaac aaatataacc aaatgtctct acaacataat
    26521 caatggcaaa agtttttgaa gcaataatac gtctttcctt ttttgcttct tatccccaaa
    26581 gaaacggata taacttatta tgtattgaat ttttttggaa aggcgaatta tgacaagata
    26641 taccttgcgt tgaaaaaact cgcggaaaaa atatcacacg tttttaaaaa gatacaaagt
    26701 aagaaagcag ctgtcaatag aatggaaaca aaaatggcga gacatcaatc agtctcgcct
    26761 tgttttttat tgtatacatt agatatggag caggttacca taaagatgat tattagtcgt
    26821 tattaaatag aatccttcgt atttttttgt tctatcacta caatatcttt atttggacgt
    26881 ttgaattgta ttccggcacg ttctagctcc tgtttcactc ctacatggac tttgacatct
    26941 tctcgtgtca tttttaaaac gtgatgaatc gcatagtcga tttcttgcct tgtgattttt
    27001 ttcttcgtat tgatcatcac gacttgcttt ttatcatatg tgtctaccaa tagcagttgt
    27061 gttcgatcta acgaaaataa tttgtaataa ttaatagccg tattcccaaa aaagaattcc
    27121 actactttag gataaaatgt cttaatattt aaattactat tcacaggtgt ttcgattagc
    27181 ttcatctcat tcctcttttc tatatagtcg atttagatcc aatcttaagt tatgttacca
    27241 tctttcctag cattaaggaa tcggttacaa ttgaaccttt aaagacaaaa ggatttacct
    27301 tttatcactt aatagtataa cataatttcg tgagaaaaaa atacaatttt ttcttgacca
    27361 tctcgttacg taaaggatta tgcttacatt tgtcaggagg aaaaataatg gagtacacaa
    27421 taaagaaaat gtcagagata tcaggagtca gtccgagaac cttgcgcttt tatgatgaga
    27481 ttggactgct aaaaccagct aggatcaatt cttcaggtta tcggatttat ggcaaaaaag
    27541 aagtcgatcg tctgcaacac atcttatttt atcgaacaat ggcattcaag ttggatgata
    27601 tccaagaggt cttagacaat ccatcttttg accaccagaa agctttaatc aagcatcagc
    27661 aaatgttgct ggaaaaacgg gcacaaatcg ataccctctt gacaactgtc caacagacac
    27721 ttgatatgta cgaaggagga agaaaaatga gtgacaaaga aaaatttgaa gggtttaaac
    27781 aacaaaagtt gaaagaaaat gaagaatcct atggacaaga gattcgacaa aaatacggaa
    27841 aaaaaaaggt tacagcatcc aatgaaaaat ggatgaatat ggataaagaa acgtatgaag
    27901 aaatgcaaac tgttgaaaag cagatgttat ttgatctcac tctttactta aaagaaccag
    27961 aagatgaaag cttagcagac cgtatcttcc aagctcataa gaagtggttc tcttacagct
    28021 ggcctgaata tcagccaaaa gcgcataaag gactaggaat gatgtacgaa gccgatgaac
    28081 ggttcactgc atattatgac gagcgaagtg gtcatggtgc agcaaaagct ttaaatgaaa
    28141 ttatccaaaa aaaggcgtaa tcttttacat gatccaacaa aaaagtacac gtaaaatgac
    28201 ctaataacaa aacagcagac acccaagtta gatttttatg ctaacttttg gtgtctgctc
    28261 cattctttca caagtttttt catcctactt taaatatatt catcgttgaa taaacgtata
    28321 aggtattttc actttatcct ttttttctgt aagaaacaat tgaaatgcca tttctccgca
    28381 agcttccaga tggtggtcga tggttgggaa accaagaagc tcgctgatca gcaaattatc
    28441 gcgtccaatc accactggtg tcttatcttg cagatagctt tgcaagatgc ctgctgcaac
    28501 catatccgaa tttgtaaaga caccatcaac tccaagctct ttaaaagaga agcctgcttg
    28561 ttttcctttc tctgcatcta tacaatccca aaaaacaagt gattcatcaa aagatggaaa
    28621 aagttgatga catagctgca aagtgatttt tgagttataa cttagcctgc cacttcgccc
    28681 caacgtgatg cccaattgct ttataccttg ctgcttcaaa taagtaagac cttctgtaat
    28741 tgattgttct cgatcaataa agacacagct tgcctgtttt cccttgattt cttcacaaaa
    28801 aactagaggt ccatattttt gatatgccaa taaatcatct agtgtattgg cacgagacgt
    28861 aatgatcaat ccatcgaaag ctttagctgc aaattcttca agataccttc gctctttttc
    28921 tttatgatag cccgtcggta aaagtgtcac tttgtaatca taatcaaacg ctgcttcaat
    28981 gatcccactg atcaactgat caaaatacgg atgattggta taaggcagaa tcactccaat
    29041 gcttttcgtt tttccataac ttaactgtct ggcatttgca ttagggatat aatcgacttc
    29101 tttcatgacc gcaagtattt ctttcctttt ttcctcatct acatatggat gtccattgat
    29161 tacacgtgaa atagtagaaa ctgaataacc tgtgagcttt gcgatatctc gaatgtttgc
    29221 cactgctgct tcgccaccta tacaaaaaga ttttcttgta aatagtctac cacagctgga
    29281 ccgcattcaa aaaactgata catttttcct tcatgcgaaa aactgatccg ctgcccgccc
    29341 caatatatat cttttgtcaa attttcgatt tcattcattg gtatttcttt tactatattc
    29401 ctattcaacc cttgaaaact gtacaacgtt aatacggatc ccttgaactc gacaaacgca
    29461 taaaaataat tgttcgttgt gccatctgtt atctctacat aagtattcat tgcaagccct
    29521 ccttttgata ctttgagtat agtgtatgaa acgcgtctca tagcaaggag tttgttttgc
    29581 caaagaaaag ttttattcct ctttcattat taccaaagtc tcttatttta aattgaatac
    29641 attataatga tactgtaaat atatctttat tattagtgaa tg
//
LOCUS       DAIGUC010000036        29572 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.036, whole genome shotgun sequence.
ACCESSION   DAIGUC010000036 DAIGUC010000000
VERSION     DAIGUC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.036"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(47..1342)
                     /gene="purB"
                     /locus_tag="NOB46_001709"
     CDS             complement(47..1342)
                     /gene="purB"
                     /locus_tag="NOB46_001709"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCI1058642.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1355..2479)
                     /gene="purK"
                     /locus_tag="NOB46_001710"
     CDS             complement(1355..2479)
                     /gene="purK"
                     /locus_tag="NOB46_001710"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCI1058643.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2472..2960)
                     /gene="purE"
                     /locus_tag="NOB46_001711"
     CDS             complement(2472..2960)
                     /gene="purE"
                     /locus_tag="NOB46_001711"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCI1058644.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3376..4683)
                     /locus_tag="NOB46_001712"
     CDS             complement(3376..4683)
                     /locus_tag="NOB46_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCI1058645.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4686..5267)
                     /locus_tag="NOB46_001713"
     CDS             complement(4686..5267)
                     /locus_tag="NOB46_001713"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCI1058646.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5383..5480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5839..7131)
                     /locus_tag="NOB46_001714"
     CDS             complement(5839..7131)
                     /locus_tag="NOB46_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1058647.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7128..7751)
                     /locus_tag="NOB46_001715"
     CDS             complement(7128..7751)
                     /locus_tag="NOB46_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058648.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7754..8590)
                     /locus_tag="NOB46_001716"
     CDS             complement(7754..8590)
                     /locus_tag="NOB46_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058649.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8607..9494)
                     /locus_tag="NOB46_001717"
     CDS             complement(8607..9494)
                     /locus_tag="NOB46_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1058650.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9510..10793)
                     /locus_tag="NOB46_001718"
     CDS             complement(9510..10793)
                     /locus_tag="NOB46_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1058651.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11476..12159)
                     /locus_tag="NOB46_001719"
     CDS             complement(11476..12159)
                     /locus_tag="NOB46_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI1058652.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12177..12794)
                     /locus_tag="NOB46_001720"
     CDS             complement(12177..12794)
                     /locus_tag="NOB46_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI1058653.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12804..13628)
                     /locus_tag="NOB46_001721"
     CDS             complement(12804..13628)
                     /locus_tag="NOB46_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCI1058654.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13621..14181)
                     /locus_tag="NOB46_001722"
     CDS             complement(13621..14181)
                     /locus_tag="NOB46_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058655.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14355..15311
                     /locus_tag="NOB46_001723"
     CDS             14355..15311
                     /locus_tag="NOB46_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI1058656.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15616..16572)
                     /locus_tag="NOB46_001724"
     CDS             complement(15616..16572)
                     /locus_tag="NOB46_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HCI1058657.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16676..17278
                     /locus_tag="NOB46_001725"
     CDS             16676..17278
                     /locus_tag="NOB46_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI1058658.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17366..18865)
                     /locus_tag="NOB46_001726"
     CDS             complement(17366..18865)
                     /locus_tag="NOB46_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCI1058659.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18881..19405)
                     /locus_tag="NOB46_001727"
     CDS             complement(18881..19405)
                     /locus_tag="NOB46_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCI1058660.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19703..20452
                     /locus_tag="NOB46_001728"
     CDS             19703..20452
                     /locus_tag="NOB46_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI1058661.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20443..21228
                     /locus_tag="NOB46_001729"
     CDS             20443..21228
                     /locus_tag="NOB46_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HCI1058662.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21197..21913
                     /locus_tag="NOB46_001730"
     CDS             21197..21913
                     /locus_tag="NOB46_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI1058663.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22015..23049)
                     /locus_tag="NOB46_001731"
     CDS             complement(22015..23049)
                     /locus_tag="NOB46_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HCI1058664.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23053..24111)
                     /locus_tag="NOB46_001732"
     CDS             complement(23053..24111)
                     /locus_tag="NOB46_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCI1058665.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(24332..25480)
                     /gene="nagA"
                     /locus_tag="NOB46_001733"
     CDS             complement(24332..25480)
                     /gene="nagA"
                     /locus_tag="NOB46_001733"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCI1058666.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(25556..26392)
                     /locus_tag="NOB46_001734"
     CDS             complement(25556..26392)
                     /locus_tag="NOB46_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1058667.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(26576..27793)
                     /locus_tag="NOB46_001735"
     CDS             complement(26576..27793)
                     /locus_tag="NOB46_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1058668.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(27942..28121)
                     /locus_tag="NOB46_001736"
     CDS             complement(27942..28121)
                     /locus_tag="NOB46_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058669.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            28176..28259
                     /locus_tag="NOB46_001737"
     tRNA            28176..28259
                     /locus_tag="NOB46_001737"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28210..28212,aa:Leu,seq:gag)
     gene            complement(28499..29497)
                     /locus_tag="NOB46_001738"
     CDS             complement(28499..29497)
                     /locus_tag="NOB46_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058670.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         8843 a         6305 c         5064 g         9360 t
ORIGIN      
        1 tatttttgct attctatttt aattgaattt tgcaactcac tcttctttat tccaaaccta
       61 ctcgtttgaa tatcacgtca acgtttttca aatgatgatg ataatcaaag gcatcgtcta
      121 tttcttcttt agataatacc gatgtgatgg ttggatcttc ttctaacagc gggcggaact
      181 gcacttggtt gtcccaagcg tacgcagttt ttggctgaac aagatcataa gcttcttctc
      241 ttgtcattcc cttatcgatc aatttcagca taacgcgctg gctataaatc aaaccaaatg
      301 ttgcagacat attccgcttc atgttttcag gaaagaccgt tagattttta acgatattgc
      361 caaaacgatt taacatgtaa ttcaataaaa tcgtggtatc aggcaagatg attcgttctg
      421 ctgaagaatg agaaatatct ctttcatgcc ataatgtgac attttcatag gcagtgacca
      481 tgtgtccgcg caccactctg gctagaccag ccatattttc tgaaccgatc ggattccttt
      541 tgtgcggcat agcagaagaa cctttttgac ctttcgcaaa aaattcttct acttcacgtg
      601 tttcggattt ttgcaatccg cgtatctctg ttgcaaaacg ttcaatactt gtagcaataa
      661 gcgccatcgc tgagaaatat tcagcatgta gatcccgagg gagaacttga gtagagattt
      721 cttgtggacg gatccccaat tgtttacata catactcttc aataaatggc gggatatttg
      781 cgaacgttcc cactgctcct gagatttttc ctgcttctac tccttttgcc gcatgttcaa
      841 atcgttcgat gttccgtttc atttctgaat accatgtggc aagtttcaat ccaaaagtag
      901 ttggttcagc atggacaccg tgtgtccgac ccatcatcac tgtatatttg tgttcttttg
      961 ctttttcgcc aatgatttcc gtaaaacgtt tcaagtcttc ccgtaaaata tcatttgctt
     1021 gcttgatgag atagccataa gcagtatcta cgacatccgt acttgttaga ccataatgga
     1081 cccattttct ttcttctccc aatgtttcag aaaccgctcg tgtaaacgca acgacatcat
     1141 ggcgtgttaa tttttcgatt tccaagatcc gatcgatatc aaatgatgca tgctcacgaa
     1201 tttttttcac atcttcttgc gggatttcac caagttctgc ccaagcttca tctgctaaaa
     1261 tctcgacttc gagccacgca cggtatttgt tctcttccgt ccagatattc cccatttcag
     1321 ggcgtgtata acgttctaac atgttttttc tcctctaatc ccaaatattc gtttgtttga
     1381 tttcttccag cgtttgctgg atgtcttctg tcaagatagt gatatgtccc atcttgcgac
     1441 ctttttttgc ttgttttttt ccatagaaat ggaattgcca gtctggctta ttctcaatca
     1501 agcgatagct ttccagcagt tgttctccca aaacattgac cattactgca ttgcttatca
     1561 aacgtacttt ttctcctaat ggccaaccac aaatacctcg aatatgggca tcgaactgac
     1621 tcatagaaca agcttcaata gaataatgtc cagaattgtg aggacgagga gctaattcat
     1681 tcacatatag cccgcctgtt tttgttaaaa acatttctac ccctaaaaca cctgaaaggc
     1741 tcactgcttc tgcaatcaca cgggcaatac gctcagcctc ctcgatcaca tcctgatcaa
     1801 tcgcggctgg agcaatcgtt tcatgaagaa tattgttgtg gtggatgttt tccacgaccg
     1861 gaaaagtcgt gaaatctcct tgaccatttc ctgccaccat gatcgaaatc tctttttcaa
     1921 acgggatcca tgcttctaaa acacaggttc cttctcttaa aaggtccatg gcaggagcta
     1981 gatccgcccg acttttcaaa acatactgcc ccttgccatc atagccgcct cgagtggttt
     2041 tcaaaacaca aggatagccg atcccgtcaa tcgcatcttg gatatccgtc ggactgacga
     2101 tcgttgcata aggagcaatc acgatgttat tcgtttccaa aaaagatttt tctaacaggc
     2161 ggtcttgcgt aatcgcaagc aagtctgtcc cttgaggaat aaatgacatg ggtaaaatcg
     2221 catttaacgc ctctacactg acgttttcga attcataggt aatgacatct gttcttctgg
     2281 caagctcttt cagcgcaaag gtgtcatcat agacactttc aatgtgccaa tctgcaactt
     2341 gtgcggctgg acaatcgctc acaggatcca gcacacctac tttaaagccc atttcttttg
     2401 cactaatcgc catcatacga cctaattgac cgccaccgac gatcccgatc gttgaaccag
     2461 gcaacaaagg tttaaccaag ttgatcacta ctttctataa cagttttagc caacattgaa
     2521 cgtctttcag ccaatttagc ctccaattct aaatcataca tggaaagcat ctgtatcgca
     2581 agtagtccag cattaattgc tcccgctttt ccgattgctg tagtagctac aggtactcct
     2641 ccaggcattt ggacaatcga aagaagcgaa tccaaaccat ttaatgttcg tgattggacc
     2701 ggtacaccga taaccggcaa agttgttttt gatgcgacca tacccggcag atgcgcggct
     2761 ccccctgctc ctgcaataat gattttgatt cctttttttc gagcgttttg tgcatattca
     2821 aacatcaaat ctggggttcg atgagcagaa acgacctttt tttcataaga cacaccgaat
     2881 tcatccaata tttgacatgc ttctttcatt gtttcccaat ctgaagtact ccccataatc
     2941 acagagattt ttgctgtcat tgtttttcct cccagttttt ctacattcat attttaacaa
     3001 tcactttttt tgatgtcaaa gaaatttcga atgttaacaa agaaaaacat tttattgttc
     3061 gtgtttatta aagataaaaa aaaggaatgt gacaaaagtt aggtcacatt cctttttatg
     3121 gataaacggt gttctcctgc caactcctcg gtcacaagga acaatattca acaaacatga
     3181 gaagcttttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     3241 ttccttcaac ggtgttcaat cagctgaccc tcggtattag ctcaaacaaa cggcaaaata
     3301 cgaggaacta tttttccgtt tgtttctcta acaatcaggt caaaacgctg atttcacaac
     3361 ctttcttttg ctctattact tcttgaaggc ttcttccaat atttcttcat cttttttcaa
     3421 tccattaaag atcaaattca atatgatagc cgtaatgcta ctcattacga tgccatttcc
     3481 agtgaacatt tgcaatgttt gcggcatttg actgaataat gtcggcgtaa cattgaaacc
     3541 cagcccaaat ccaacagaaa cagcaacaat caatagattt ttatcattgc tgaaatcaac
     3601 ttccaacagc atacggattc cttggactgc caccatcccg aacatgacta acattcctcc
     3661 accaagtacc ggctcaggga tgatttgtgc taacgcaccg attttaggga ataatcctaa
     3721 aacaatcaag aagaatgcag agaaatagat gggttttctt gttttgattc ccgaaagttg
     3781 aaccaatccg acattttgag aaaagccagt ataagggaat gtattgaaaa taccgcctaa
     3841 gataacggca agtccttctg cacgatatcc ctttttcaat tcttcttctc caacattttt
     3901 cccagtaatg tcaccaagtg caaaatatac acctgttgat tctaccatgc tgaccatgga
     3961 aatgatgatc attagtaaaa tcgaccatac gtcgaaagtt ggtttaccaa aataaaaggg
     4021 ttgtggaaca tggaacaacg gcgcatctcc aatcgcgctc agatcaatca ttcccatgaa
     4081 agcagctaag atgcttcctc cgactaaacc aatcaatacc gcgattgaac gaatgaaccc
     4141 ttttgccagc atttgcacgc ctacaattag gagaatcgtc acaaatgcaa gtagcagatt
     4201 tgttttgtca ccaaaatcag ctgctgttgc attacctcca cccattttct cgattgctac
     4261 aggaatcaaa gtcaaaccaa taacggtgat aaccgttcct gttactatag gagggaatag
     4321 ttttttaatt ttagaaaaga caccagaaac taacacaaca aagatcccag aagcgataat
     4381 agatccgtag atagctccta ctccttcatt ggttccgatc aagatcagtg gagctactgc
     4441 ttggatcgca catcctaaaa cgacaggcaa gccaattccg aaaaatcggt taactgtcaa
     4501 ttgcaataat gtcgctaatc cacacataaa gatatcaatt gaaatcaaat aagtcatctg
     4561 ttcttgatta aagcctagtc ctgtaccgat caaaagaggc accgctactg ctcctgcata
     4621 catcgctagc agatgctgca gccctaaaac cgcagctttt ccattttgtg tttctttttc
     4681 cacgattatg cgtcctcctc aagaaactca acttgtccat tcgtcaagga agcaatacgc
     4741 gcaagagaaa cgactctcaa tcccatttct tcaagtaact gacgtccatc ttggaaagac
     4801 ttttcgatga cgatcccgat tccttctact tgcgctccag cttgctggca taattcgatc
     4861 aatccttttg ccgcttgtcc gtttgccaag aaatcgtcga taatcaatac tttgtcttct
     4921 gaagataaaa atttacgaga aatagaaatc gtacttgtca cttgtttcgt aaaagaataa
     4981 acagaagctg tcaataattc ttcatccatc gtcaaacttt ttgcttttct agcgaagatc
     5041 attggaacat ctaattctct tgcagcaaat aaagctggtg cgatcccaga agcttcaatg
     5101 gtcacaactt tcgtgattcc ttgttcttta aatacttctg caaaccgttt tcccatttgt
     5161 tccatcaata cagggtctac ttggtgagtg acgaagctgt cgacttttaa tacgccctcg
     5221 cctaatatac gtccgtcttt ttgaatacgt tcaactaatt ctttcacttt atttgctcct
     5281 ttatcattta ttaataccga aataaccgct tttgtgcaaa aacctactat gtttctgtta
     5341 aagaaaaaca ccctccactt tatcataaga aaagaagggt gaaatagcca atcttttact
     5401 tatagtccag catttacggt actggctaga aactgtcatc catattatga cgatatataa
     5461 gtaggtatgt aaaactaata atagtgtaaa ttcattttct tgcaactgtt ttgcacgtga
     5521 aggcagtttg ccatatttga ataaaaaatg ttgtttcaaa tattgaaaac agtctaacac
     5581 tactttctga aactgacaac gtggtttact tatttttttg taaaatctaa tgatttttaa
     5641 tgcattattc ctttttgttc gggtttaaat agttattttt attttctcct atctaaaaaa
     5701 gcagcccaca taaaaagaag gcatgacaaa aagcatgtca tagccccttt ttccgaataa
     5761 atagtgttca aaagacagcc tatcggcaat aaggcaagat tttataaact acgggaagta
     5821 atttccgtaa atctattctt attcttttaa gctgacaagc tcgtcaatca ctactgcttt
     5881 tcctgaagca atagaatgat ttgctgcgat tcctgtcaaa atcgacaaaa taccatctac
     5941 gtgagttgct gcccgattcc acggatcttc ttctttttct tcaccaaata gatcatctaa
     6001 taaacgcgga tctcctccgc catgtccgcc cgcttcttgt tcgacgatta cctcatatgg
     6061 ctcaccgaac atcggataga catggatgga ctgaagaacg gctgctcctt catccttttt
     6121 atctccacct gcattgatgt aagacttttc gatcactttc atttcgatcc gtcctttgct
     6181 gccattgaaa gaaacattga atccttccca cggcatatac gcgtttagcg aatacgtcaa
     6241 aatcgcacca gtttcatatt tgaccgttac gcctagtgta tcttcaatag agatatcatc
     6301 ggaaaataca ctgcggtcac gaatatatcc actgtctttt tctgcttcta aatacatttc
     6361 tcgcaattcc tcattggctg acaggtctat agcaaatgga tcagctttag ctagttcgct
     6421 tccatagcat cgactgtaaa atatttctac tccgcgtttc tccgcattat gcatcccata
     6481 aaagtttaat ccaccgaatg caaatacctt ttggggacgg ctgttcaacc aaaaattcac
     6541 tagatcaaaa tgatgggtag atttatgaac aagaagcccg ccgctattgt gcttatttcg
     6601 atgccatctt ctgaaataat ctgccccgtg ttgcgtattt aacagccatt cgaagtggat
     6661 agaaaacaca tcaccaatca catcactttc tatcagttcc tttatcttcg tgtgatacgg
     6721 tgcataacga taattaaaag tgactcgcag gcttcttccc gtctgttttt ggaccgttat
     6781 tatttcttga gctttttcct catcgatagt cagaggtttt tcgcaaataa catcatatcc
     6841 ttttttcatt gcacgaatga tataatcatg atgcgttcga tctactgacg taataatgac
     6901 ttcagccggc cgtacgtcat ccagtagttg ctcaaattgt gatggcatac atgtctttac
     6961 ttttttctgt ccatacttgt tcacaagtat ccgatttgca taatccatcc ttgtttgaga
     7021 tacatcacaa aaaccgacta gttcacaagt ttgatgatac gtagaggcaa ttgcctcata
     7081 aaaaaaacgc gctctcccac caagtccgac ttgtacatat tttttcttca tttaaagtca
     7141 ttctcctttt cttttaagca aaatactgtg acaaatggca gccctggata cagtaatgca
     7201 gtgagtaaaa aatcatgctg tatacaccag aacagtccat acaaaaggca taaataccac
     7261 agaaacccct tgacgttttt tgacaacagc cagatattcc ttttgatcaa ataaacaaga
     7321 ctatctgctt tatcttcttt gcagatatca attagcgtac taaaaaaact atgggataca
     7381 aaaagcaaca gacacaatag aaaaggaatc agataccaag ctccaatctt tcccactaat
     7441 aaataccaat caactgcaaa aataatgaca aacagctgaa acaacgtaat gatgaaacac
     7501 atccgtttga tttttccttt cctccaacat accttttttt ctgccaagta atggacagat
     7561 agataataag aaggatacat catcaaaaaa taaatcagat agacaacacg agcagacagc
     7621 actaatccta aagtgaacaa acatcctaga actaaagcga aaagagcatt actgataaga
     7681 ctggttaaaa aaatccgaca gacatagtag ttgagcttgt aaagaaacat ctcttctatt
     7741 ggctttttca tattcagccc ttcagaccgc ttgtactgat cccctggaca agatatttat
     7801 tgaagaataa gaaaatcaga aaaaccggta gcagcgacaa cgtagacatc gcaaacatac
     7861 tcgcgtaagt cgtactagat ccagcgtctg caaataattt gatggcaatc gataccgtgt
     7921 aagatctcgg cttgtttaaa taaatcaatg gtcccatgaa gtcgtcccat ttccaataaa
     7981 actggatgat gatcgtcgtg atgatcgaag gtttcagcaa aggaaaaata attttggtaa
     8041 agacactata cttgctgcat ccgtcaataa tcgctgattc atctaactct ttggggatgc
     8101 tgaccatgaa ttgcatgatc tggtaaatga aaaatgcttg tccaaaaaaa tgtggtaaaa
     8161 tcagcggcac atacgtccca accaaattca gccgattgta aataataaac tgcggaatca
     8221 aaatcacttg tgcaggaatc atcatcgtta ctaacatgac gacgaaccag aatctttttc
     8281 ctttgaaatc gattctcgat aatgcgtaag caatacaagt cgagctcaga actgtcccta
     8341 tcgtcgaaac tgcagagatg acaaacgaat tcctaaagaa agtaaaaaat gaaattccag
     8401 caaaccccgc ccatcctttt gcgtaatttt cccattgaaa agtctctgga atcaaattca
     8461 gcgaaccact cataatctct tgatccgttt taaaagaacc tgcgatcatc cataagaccg
     8521 gataaatcat gactagacct aatagcaaaa taaaaccgta ttgaaaccat ttcgttactg
     8581 tattattcat ttcttcctcc tctcattcac acaacgaccc atttttttga tgatttgaaa
     8641 atcagaaagg tgacagctcc cataatcaac agcatgatcc acgaaatagc actagcatac
     8701 cccatagaat taaaagaaaa agcttggtta tacacataaa gagcataaaa gttcgtggca
     8761 tcattcggac caccttgggt aatgataaat gcctgcgtaa aagtcataaa cgccgcgatt
     8821 gtctgcataa ccaagttata caaaatgatc ggcgaaagaa gaggtaacgt gatcttgtaa
     8881 aacgtctgcc atttgttcgc tccatcgatc tctgccgctt cataatacga gcctgggatc
     8941 tctttgatac ctgcagcaaa gatgatcatt gccgaaccga attgccaagc agacatcaaa
     9001 acaagaggga tcatgaccag tttttgatcg ctaaaccagg aaagcgcagg tgcgcctaat
     9061 cgttccagga aaatattcac taacccgttt ttagaaaaca actcccgcca aactagagcg
     9121 atagaaatac tgccaccgat caaactaggc acataataca aagaacgaaa gaaagtcgtt
     9181 cctttgatat tcctcgttaa aagataagca atcaatagac caaagatcag tttcacaggt
     9241 acagatgcaa atacatagag aaaagtgact cggatggagt tcaaaaaacg ggcatcactc
     9301 agcatcttta tataattatc caagccgatc catgagactg gatttcccaa acgataatcg
     9361 gtgaacgaat aataaagtga caagatcatc ggtatcactg ttatcaatag aaatcctagg
     9421 atgaatggag aagcaaatac gtaaccgacc acattgtctt gatccaagaa ccgttttagt
     9481 ttttcttttt tcatgccttc ctcctgctgc tatcctagaa tgtttgacgc aaactcataa
     9541 agactctctg ctgcttcttc tgctgttact tcttcataaa tgactttttc aactaaaaga
     9601 ttgtattggt cttgaatttc cggattcaaa gcactatcaa agacattcac ttcgccgttg
     9661 tccatatcgg aaatcatttc taaataatca aatgtcgctt gcaaagttgc atcatctgca
     9721 cgagcgagct gttctcgaat attcgacatg attggtacac cacgttctcc ttttaaaatt
     9781 tcattggctt cttcactgtt ttgaaagaaa tcaataaact tagcagcttc ttctttatgg
     9841 gctgagcttt ttgccatact cagcatttgc gaagaacgta aagggatacc agattctcca
     9901 tctgcttttc tgcgaggtgg attaatcaac tgaatctcca tatcttcagg agcccctgac
     9961 aatatttctg tcaactggtt acttgataga aacaccattg ccgcttctct atccctaacc
    10021 gcctgaaaag acagatccgt cgtacttgca gctccaccac ctggttctgg atgggcccct
    10081 ttgtctacca gatttttacg cagctggaaa aaatctgtta gatagtctgg attttcaaat
    10141 cccaagctgt tagatagatc ttcccgatta taaaaattca atcctttctc aacttgtggt
    10201 atttgaataa tacagccagc tataaaatct tcgaatcttg aaatagcata gattcctaat
    10261 tcttcagtga tttgatagct gatttgttca aattcatccc atgtccaatt tgaagctggt
    10321 tcagggatat ttaattgttc aaatatattt ttattgtaag caatcgcaaa cgaattcacc
    10381 ccgttagaca gtccaactaa ttgcccgtcg taagtcgtcg ttgctaaata ggattcatct
    10441 gcattagaaa tatcaattat cccttgctcc acatattcat ctaatggttc aatctgattg
    10501 atgtattgag gaaattgatt gttcagttgg aaaatgtccc agatatcatc tgatgctgct
    10561 agtgtaccta attttgtgta atatccttca taatcataaa attcataatc gatcgtcaca
    10621 tggggatttt tttcttcata aagctcgatt acttttactg ttgcatcgtg tcggacttgc
    10681 gaaccccacc aagccatgtt cagcgtgatt tttttgtcat cttcttgccc acaagccgtc
    10741 aagaagaata acataacact taaagctaag atgattctca ttcttttctt cattctctgc
    10801 acctctactt ccattgttat ttttcaatat actgtatttt tatacagaac atatttatta
    10861 aacgatcttt ttcaagggga ataaaaacca agacttgcct tatcgttctg cctaggatga
    10921 acaactcaat actttcaaga aaaattagat agtgctgatt cttctttcat cgctaaaaac
    10981 acttcttgct tcaatgatgg gaggataatt acgcaaagaa aaaaggatat cagacaactg
    11041 cccaatatcc ttgacatagc taaataagca tgcttcttcg tgtgcgctct tccctaaaaa
    11101 acagaaaaat aactagtaat tctgtatgaa attaggtaca atatacacgt cgatgcacaa
    11161 gcattgacta tggcaacttg attggtcagt tcccgctgac ttttcaagcc ccgacaattt
    11221 agctgctact aaattgtcgg gtgccttttt tagtttttat tcgtttttca ttctatagaa
    11281 agcgcttcaa taaatcaaga catttttttg ttagaatgct aataataaca aaaggtttta
    11341 actcttctta tgtacattac aggtaaaaaa acaaaaaaat ttctcttttt tttgaattct
    11401 gaacaaatag tactggagta caaaagacga ggaagagcca ctatctgctc ttcctcgtct
    11461 tttgattctc acctgttatt catgattctt tttctcagtt tcccgatatt tttccatttt
    11521 acgactaaaa agctctccgc tacttggtgg cgtatatgtg atggcatttg ctcctgcttg
    11581 aatggtctca gcaatacttt cttccgttgg accacctgtc gcaatgatag gaagttcagg
    11641 atatttttta cgaaaatggc gtactgcttc tgcagtttct ttacctgcac tgatattgat
    11701 aatcgaaata ccagctgcta acttttcatc tatttctgta tatttcgacg ttaccgtact
    11761 gataactgga atatcaacta ctcgacaaac ttcttttact gtctctaaag gcgtaggacc
    11821 gttcaaaacg acccctaacg aaccttgcgc ttctgcgaac atgctcatgt aggaagaacg
    11881 agcaccttgt gtcaaaccac cacctacacc ggagaaaact ggaatgtcag ctgcctcaat
    11941 aatgctttta gtaatcgctg gatgaggtgt aaaaggatac acagcaatta ctgcattcgc
    12001 atttgtatta cgtatgatcg caatatccgt agtaaagatg atcgaacgga tcaattttcc
    12061 aaatatcttg atcccgcttg cttctaaaat gatttccggt actcttacga tatcttttct
    12121 caattccgtc atgatttctg gcgtaaattg ttctgccatc agccacttct cctttgctat
    12181 ctccggtcat actgattcaa ttgatacgtc tcgatgacct ggatgatttt ttgcgcataa
    12241 ccggggtctg tcgcataacc tgcatcttgc aatgcttgtg cggcttcctg atagttggtg
    12301 gccgtaatca ctttttcata cagcgcagga ttccaatcta ctccttggac gaacagttgt
    12361 gtatggtcat ccatggactg ttcccatgaa tcatacactt tgaagtctcc ttggatagtt
    12421 atccattctt cgttaacaaa ttcctttgtt tccaggctta ctttcttctg atccccataa
    12481 gccttgatcc cgaaaagatt attgtatttg ctagccaagg tactttttcc ccaatttgat
    12541 tctaatatag cttgtcctaa aatgatacta ggaagcactc cataaccatc ttgtagttct
    12601 tgggcatgcg gaacaagccg ttcaataaat tgctgatggg attgcgcttc attttcttgc
    12661 tgattatcag taaaaggaga agacagattc ttcaaggaaa aaacaaaggc taagagtatc
    12721 actgctacac cggcaaccac tgctggccaa cggatattct tgcgcttttg ctttttccac
    12781 ttttttttcg ccatgatcaa ttcctacttt tcatttaatt cattcagata ttcttctagc
    12841 gtcaattggt gtttggtgat atactcagcg ttttctttac cgacataacg taagtgccaa
    12901 ggttcatatg tgatcttagt tatatcttcg tgtccttttg gataacgaac gataaatcca
    12961 tactgcgcag cattatctgc gatccattta gctccaggct gatctccgta acttgcatcc
    13021 aatacagtag aaggataact gttgtaccag ttttgatcga cgacatcgac tgccagacct
    13081 gtgtggtgtt cgctgtatcc tggctccgta atcgtttctt tagtaatctt tgtcgcctcc
    13141 tcttctgata caccttgacg actcatcaca tcttggacat tttgttcgaa aacttgttgt
    13201 tgggatgata cagaccggta agctgagacc atcactaatg gaaatccagc tgcttcagca
    13261 gccttggcaa atgcttcata ttctggagca atgcgtttgt cgatcaagta tccgttactt
    13321 aatgatgcca attgagtaga ctcatcaatt tctttttcta atttgtgatc tggaccaacc
    13381 aaaactagct tccaatcgtc tgttttaaca tctggcaatt gtttggacgt acgatctttt
    13441 gtttctttgt cctttacctt gctgctggtt gtttgactgt tcttttcttt actagcagtt
    13501 gttttggtgc ttgttcgttc gactgcttga ttgccggctt gaacatgcga atcatcatcg
    13561 ctaaaaataa catagcccat tgctgcgatc ataatcacaa ctgctccaaa tcctaaaaat
    13621 ttattcactt gaaaaatcct ttcgttgttc ttcacgttcc ccattcgcct catgaacgta
    13681 agtttcttcc agattttcat tcacccaatc gagaagttcg attttttctc cttcgatctg
    13741 tttttgaaca tctgctggca gacgaaaatt caaaatatca tcatagcccc attcatcata
    13801 ttgaatactt actttcaagt caaggtatct accagcctgc tgattatttt tcaaagggat
    13861 cagctcgact tttgctgctt tgctgctaag ccatttttgc gcgatgcgtg ttttgatttg
    13921 cttgtactct gcaacggcaa cgtttcgttt ttcgggaaaa ataatcgttt gacgcaaaat
    13981 cttttgcgtt agcatccatt cataatcagt gaaaagattt tttactttct gcatcgcttc
    14041 agatggcaga tttttctcgc catctttcca tttttgccat tgttctggac tgatcagcaa
    14101 gtattcatct aaaaaatttt tttcagtttc aaactgttct aataatacac tcataataag
    14161 atcaatatat acttgatgca cgtttatccc ctccttttaa ctattctact taagttttga
    14221 tcaaaaagca cctcttaaat cgctgctttc atttttttta atgtttcaag tcctctcctc
    14281 tttattcttc gtgatttttg ttataataat agacagacaa gaaactcaat ccaactatga
    14341 aggagcgttt tcagatgaaa aaatatcaat ggggaatcgt tggtcttggt accatcgcac
    14401 atgagtttgc cgaaagcttc aatcaagaga cgagcgaact aacagcagtt gcttccagaa
    14461 cttcagaaaa agcggaaaac ttcgctcacc gttacaatat tccaaaagct tacggaagct
    14521 atcaagaaat gttagacgat gctgaaatcg acatcgtgta cattgctgta ccaaatagac
    14581 agcatatcga ccatatcttg gcagcattgg aagcaggcaa acacgttcta tgtgaaaaag
    14641 ccatcacgat gaataaaaaa gaactggctg acgctatgcg cttagcagaa gaaaagaatt
    14701 tgatcttagc agaagcgatg acaatcttca acatgccact ttatcagcag ttacgctcaa
    14761 taatggatac aggaaaactg ggggctttaa aaatgatcca agcacctttc ggcagttaca
    14821 aagaaccaga ccctaaaaac cggttcttca atccagaatt agctggagga gctctgttgg
    14881 atatcggtac gtatgctgta tctttcgctc gtttcttttt gagctctcaa cctgaagtag
    14941 ttgcctctac aatggttcct tttgaaacag gcgtggacga acaatccgtc actatcttgc
    15001 gtaacaaaga aaatgaactt gctgctgtca gcttgacttt tcaggcaaaa atgccaaaag
    15061 tcggtatcgt tgcctttgag aacggttatg tgacgattgc tgattacccg cgtgctgatc
    15121 gtgcggagat cttatttaca gatggtacaa aggaattcat cgaaagcggg aatacatctg
    15181 aagcaatgaa ttacgaaata aagaatatgg tacacatgat tgaaggtgac ttgcccaatc
    15241 gctctctctt cttgacaaaa gatgtcatcg aaatcttgga tcaaatgcaa gttctatgga
    15301 aaaatatgta attttaaaag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
    15361 caaacaaaaa tagctcctcc tatttttcgt ttggctggac ttattaccgc agaggaaagc
    15421 ttttgaacac cgtttaagaa agaggttgtg agcctaccgt tcagctccga gtcacaagga
    15481 gcaatttcaa aaaacagctt ctcatgtttg ttgaatattg tgacttgtga ccgaggagtt
    15541 gacaggagaa caccgtttaa agaagaggtt gtgaaatcag ctttttgacc tgaatattag
    15601 ctgaattcac aacctctatt tttggatttt ttgttgggag aattctgcct tgatttcaat
    15661 aaaactttta aaagactgca aaaactggaa caattctgct cgatcctcga attcagggcg
    15721 actagtcggc agaggcattt gccgatacaa tacataaact tcttcaatac gtgttaaaat
    15781 ttgtctgcca tcatttgact ctgaaaatgt ttctgcagta taaatcaata aaccatagat
    15841 atgttttcca taataagctg gttgctggat tctctctaga ttttccagca tgtctttaat
    15901 cacattggcc tgtgctcttc tcatagagaa gtaagtttcg tagtatagcg gctgtctgag
    15961 ccagtagttt tcttgatgtt ctctggcatc ttcttggctt tcgcgaatga atgtcagtaa
    16021 atgttcgcat ttgatctgca catcttcttt attttctgat aaaagaaatt ctgccatttg
    16081 tctcaaaata tttcgaaatt ctttttcgat ctgtatttgg ttttccttca gctgcttcgt
    16141 acgatctggc atgtaaacat ttgcaagcaa agcaaatact aatccaatcg ccattaatcc
    16201 cgcttcattg ccgatcagct gccaagacat gttttcctcc actaaataat gagtgaccaa
    16261 aaccgaattt actactatcc cttcggttaa tttgaagcga gaggcaagcg ggatgaacag
    16321 gaataaaaaa agactgaagc caaaaatagt atacccaaca gcaaaaaaac tgaacagtgc
    16381 tgttgccgta gctaatataa aggctgcgat tcgattcatg cccgtacgca atgtagagcg
    16441 cttggtattt cctacactta ataatgcaat gatccctgca gctggccaat acaacagcga
    16501 taagctaccc gctgtgacca tcgaaaagaa gacactgatc actgttttga ctgttcgcat
    16561 tcctatacgc atttacttcc ccctttttta ttttaattat acttgaataa tgaaaaacta
    16621 gctatcagac aaaagtttag gtatgatagt aaaaagacca aaaaggagaa tctctatgca
    16681 atttggccgt tttcgactag gtatgcgtac gatcaaaagt gccttagctg tttttttatg
    16741 tatcttgttt tttcatttga ctcaacgagg aatcccgatg attgctgcat tatctgctgt
    16801 tttttctttg cgtcaggact tgactacaac cgtttctttt ggaaagtcta ggatcatcgg
    16861 caatacatta ggtggtacat tagctatcat ttattttttt gtcaaaagct attttcacaa
    16921 tgattttttg gtagaattga tcttgcttcc tattctagtt attattgtga tcgtcgtgtc
    16981 agatggtatt aacaataatt ccggtatcat ttccgcaata gctacgttgt tgctgattgc
    17041 gttgagcatc cctcaaggcg aatccgcttt gtatgctatc caacgtgtac tagatacttt
    17101 tatagggaca ttcattgcaa tcggtatcaa tttctttctt cgtcctcctg aaacagaaaa
    17161 gaaggaagaa ctatcagaag atttggtcga actccaaaag aaagaacgat tgctaagaac
    17221 aaatttacaa gagatagaag ctaagatcca aaaacaaaag aaaaatagcg aggactaatt
    17281 ttcttttgca ataaaataaa aaaatggaga gaagaacttt aaaaagtctt cctccatttt
    17341 tgattgaacg gtgaagtgta ctactttatt cttccttcat cgagttttgt tctgcctctt
    17401 ttggcgcttc atacatattt acttggctag tagtcccacg tgtcgacaaa ttctctacga
    17461 tttccttcaa gtcaagtcct gttgtcgctt ttagtgtttc ttgagtagaa gaaagcaaat
    17521 ttgtggcata atttgtcact cggttcgctc cactggtttc tcctgaactg cttcctgtat
    17581 cgacaacaga gattttttcg atatttccta gcggctgtgc tgcttcgcgc atcaattgcg
    17641 gtagcatatc gataaccata ctcaagacag ctgcttcgcc atattccttg aaggcattgg
    17701 cgatcttttg ttttgcttcg gcttctgctt ttccttttgc tagtgctgct tcggcttctg
    17761 cttgtccagc taaacgtgtc ttattggctt ccgcttctgc cagtgcttcc acacggaatc
    17821 gttctgcttc ggcttcagtc acttctttga ctttttgagc ttgtgcttct tgttctttag
    17881 cgtaccgatc ggcatctgct tttttcttca cttccgaatc atattgcttt tcacgacgtg
    17941 tgatttcttt ttcttccagt tcgatttgtt tttggcgttc tacgatttta atctgcattt
    18001 cctgttcgat tacttgttgt tgtgctcggg cactttctaa attgtaggct tggtctgctt
    18061 ttgctttagc aacatcttgt tcttgtttgt aggttgctaa tttcagttct ttttctttta
    18121 atgattctgc gatctctgtt tgtcgctgta attcagctgc ttgtgattct ttttctgctt
    18181 gagctttttt gatacgcgtt tcttttagag cttccgcttc tgctatatct gcatctcttt
    18241 tgacttgggc gattcttggt ttccctaaag agtcaagata accgtttttg tctctgacct
    18301 ctttgatagt gaaagaaacg atgatcaacc ccatttttgc aaggtctaca gaagcgactt
    18361 cttgtacgct ttgactgaac ttatcgcgat tttgatagat ttcttctaca gtcatagaac
    18421 caagaatcga gcgcaagtgt ccttctaata cttctcttgc ttcattttcc agttcttctc
    18481 ttgtcttgcc taaaaactgt tctgctgctg tagcaatctc ttctacagat gaaccgattt
    18541 tgatgatcga agtaccatca cacatcaccg gtacgccttg ttccgtatac acttcagggg
    18601 tggagacgtc caatttactc gataatagac tgatccgatt cgaacgttga aaaactggca
    18661 agacgaatgc gccacctcca cgcacaattt tgattttgtt attgctttca tcaatgtgca
    18721 catttttgct tcctaaataa cttccactga tgatcaacgc ttcatccggt tttgctgtct
    18781 ggtacttcgc tacaaagacg atcagcaaca tcagtaaaat caaagctgcg attgcgatcg
    18841 cgataaaaac aactggtatt tccatttaac acacgctcct ttaagctttt atcatgcttt
    18901 cataaggcat gacataacag attctttcct tgatctcaat gatcaatact ttcgttcccc
    18961 gctcagctgt ctgttcttgg gggctgtaaa aacaagctgg acgactaatg gaaccggtaa
    19021 cacttttcaa ctgaatttct cccatacctc gtacagggat cggtgtgatc acaacagcta
    19081 cttgtccttc cagagttttt tcagaagacg acatcgttga ttcggcatgt ttcatcggca
    19141 tcaatatata gaaattaagc aaaaatacca acactatcga tatgcctcca ctagcaataa
    19201 ataaaaataa agatgattga tctgttaaac gctcacctag aaaaccaaat aagcttgtga
    19261 aagttaacca agggataata agcatcggat caagcgggcc atcaaaatcg aatacatctc
    19321 caaaaataat caataggact gccaatcctg cacaaatcag caatgtatac caataaatcg
    19381 tctcaagtgc gattccccct atcatataca cgcctccttc catttctacg tctatcatac
    19441 caatgtttga aaattctgta tagcttcttt taccgactca gtggtgtttt ttataggaag
    19501 gttgtgttta tcgttgacaa tttgttaaat ttttgttttc atgttaaaat tttcacaata
    19561 aattccttcg aggtagccta tgtttccttt ttttaagaaa aaaccattaa agctccagaa
    19621 cacgatcatc cttgtcgttt gtttctccac attcgtttct ttgattgttt ctgccatatt
    19681 gatcaggaat tttattcttt cgatgaaccg atctagtgtg tcagataaaa tctctagcat
    19741 tgctaaaatc gttgccaatg ataaactcat ccaaaaaaag ctgcagactg gtgacccgac
    19801 acatgcgatt caaggaataa caaatgaaat catgattgca tcgaatttag attttatcgt
    19861 tgtcatggac cctgaaggca ttcgatattc tcacgcagac ccaagttaca tcggtcttcc
    19921 tttctcaagt catgaagatg tgaaaaaagt gattggagga caagaatttt tctctgaaaa
    19981 agaaggaatg ttagggttcg gcttccgcta tttcgtccct atttattatg atcaagagat
    20041 tattggtgca gtttgtgttg gcttaacaaa caacacgatt gacaatcaag tcaaagatgg
    20101 acaaaaaatg attgtttttt cattgattat tggacttagc gtaggcatca taggcgccgt
    20161 ttttcttgcc caaaaaatga aaaaagtact gcttggactt gaaccacaag aaatagcaga
    20221 acagttaagt gaaaaaacga ttatcgaaaa tgaagtagat gaaggaatct tagccatctc
    20281 ttctgataaa actatcctct tgatcaatac acctgcaaaa aacattttct accaaacaga
    20341 gcagctattg gatttcgaag taggaaaaaa atcagtgata atctatatga cgttttgttt
    20401 aaagagacga ttgagcatca aacgaccgtt cggactcaat ccatgtattt aaatgggata
    20461 gaaactattt ctagcgttac acctcttttt agcaatgacc gttttttagg agcagtcgca
    20521 actttacgaa atcgatcaga agtaatgaaa ttaatggagg agcttggggg gacgaaacaa
    20581 tatataaact ccatgagagc tcaaacccat gaattcatga ataaacttca tgtcatttct
    20641 ggtttgattg atttgaagaa gtatgaagaa gtcacccatt ttatccagca gctaaatcaa
    20701 aattataaaa aagagattgg ccaagtctca agtctgatca aagtacctgc aattgccggt
    20761 tttttattag gcaaaataaa cgaagccaaa gaacaatctg ttgaaatgct gttagaaagc
    20821 gattctttta tccctaaaat ggagatggat gactccatcc attcactttt gcaagtgtta
    20881 gggaacttac ttgataatgc aaaagaagcc gtgctacaaa aacatgaaag aaacggacag
    20941 gtccggattc atttaaacta tgacacagaa gctgaagtat tcatcgtgac cgtctgcgat
    21001 gacggtgtcg ggatatcaga agaaatctca gaaaaaatat ttacgctagg tttttcgacg
    21061 aagggaatca atcgtgggtt tggattgaat ctcatccatt caatcgtcaa acgccacggt
    21121 ggatttttag aattttccaa acaaacaaat ggcggtacaa tcgtctatct agaattacca
    21181 aaaaaggaag atcaaaatga tgacaaatgt cctgataatc gaagatgatc caatggttgc
    21241 agaattgaat cgtacttttg tggaaagcat ccctaatatg aacgtaatcg aaagtttcag
    21301 aaatgtagaa gaaggaaaaa aatatttcag acaaaaaaac gcagatctgc tgctgcttga
    21361 tgtatacatg cctggcgaaa gtggtatcca ttttttatct tggcttagac agcaaggaaa
    21421 tgatatccca gtgattttga tcactgctgc agatgatatc gaaaccataa agaatgtgat
    21481 ccgctacggt gccttagatt atttgatcaa accgttcact ttgcaacgtt ttcagctggc
    21541 gatcgaaaag tatcttgctt tctctcagac aatccaaacg actgaaaaag ccgatcagaa
    21601 attgatcgat caagtattca accacaccac tcccattcac gaaataccat cattcatcga
    21661 tttgcctaaa ggtctgtcaa aactgacttt aaaaaaaata agtgcattta ttctaaaaga
    21721 agatactatt ttttcaacaa aagaactggc tcaaaaaagc tcactgtcac gtatatccgt
    21781 caagaaatat ttgaattttt tagtagaaca agatatattg aacgaaagaa tcaaatattt
    21841 ggaaatcggc cggccgctaa cctgttatga attgacaaag aatgggcgga aaaagctcac
    21901 agattactgt tgagtcatcg aattatccca tacaaaatag tccaagtata cagaagtaac
    21961 aactgtttac ttggactatt tttaaacatt ttattgacga atatccatgt tttcttatct
    22021 taattgacgg gctttaggaa gagatacctc atttttcgtt tttccagttt ctattatttc
    22081 acgaaagttc tcgaaacttg tcgaaatcat atttgataat gcctcatctg tatttgaacc
    22141 tacatgcggg gttacaagaa ctctagggta catttctact aattgctgga tagcagggtc
    22201 tggaatcgtc tcccatggct tgaaggatcg gaaaaaaacc tctgtttcat ttgcaaaaac
    22261 atcggttgca aaaccagcta aatgattgct tttcaaagct cttaaaatag cttcattatc
    22321 ttgaagctct ccacgggctg tattaatcaa gatgctacct tttttcattt gagctaaaaa
    22381 tccttcattg atcatttgat cgttttcacc tgggatatga ggtacatgaa tactgacaat
    22441 atcgcttttg gctaataact cttcaagcga gtggaacgtc aatacttttt tagcagcttc
    22501 tgtctgatga atatcgtagc cgatcacttt ggctcctagt cccttaaaca aaacagcttc
    22561 cgtcaaccct atcctgcctg ttcctatgat ccctactgtg caatttctga tttcacgact
    22621 aaacatttgc tcatccactc gaaaatcttt gaaagatgtt cggatcgtcg tatacgcagt
    22681 atttctcaaa agcatcatgg caaaagtcaa agataactct gctatcgcat ttggcgaata
    22741 cgatggtaca cgggctactg tcataccaaa atcagctgcc gcttgtagat cgatatgatt
    22801 gactcccaca gtccgtgtaa aaacataacg aatcccatat tcctgcattt ttgcaagatt
    22861 ggtctcatct gctatacaat ttcccctcaa caatacagca tcatggtcct ttgctgacac
    22921 gatattgtca tgtgtcaaca gttcttcata aagactgaga tcataatggt aaatattcaa
    22981 tttttcaaaa aaatctatct cgttcggacg aacaccgtaa catgcgattc tcatactttc
    23041 ttcctccatt tcttatgaaa ataaacctat gccatgaatc atttgtaata caacgatcca
    23101 tacaggtgtc agtaccacag caaaaatagt tgacagtaag gatgcattgg aggctaaaag
    23161 tgcctcccta tcaaaactga tagcataggc tgctgccact gttgcagctg gtgtagccat
    23221 catgataacg attgttgcca gtgcttcaaa attgactggt agaatattcg ttgccgtcaa
    23281 aactgctaga atcacgatat tcaatgcagg tacaaatacc actttgacta gactgtaata
    23341 ccatgaagtt ttttcagatg cagctttttt gaagcttact tcacctaatg ttgcgccgat
    23401 tgctagccac gccaatggtg aacttaaacc agctaaataa tccatcggct gaaatagcca
    23461 cggtgcagtc tggtcaattc gcaaaaacgc tacttggctt atctctcctt ctgcacctgt
    23521 aactgacact tgtggcagat acccttggaa cagccaaatg aaaaggccgg caaaagtagc
    23581 gataatgatt ggattgacga acatcgcttt gatattttta gcttccatct tcaagccact
    23641 catttttatg tatccataag aatacaaaaa gattcggtag ccaatattga aaattgagga
    23701 atacatcacg ccgacaggac cataaatcgc actgacgata ggcgttccga aaaaggtcgt
    23761 agaaccaaag atcgtcagga cacgcaacgt tgtttgctta tcccctttat agcttaagaa
    23821 aaaaggtttt gaaactagaa taagaataat ataaataact aatccccaaa tcaagacatt
    23881 gattccttgc atcagtaatt ctgtattgat atcttgcatg aaagctcgaa atgccagtgc
    23941 tggcaaagcc actgttaaga cgactttcga tagaattttt ccaacagatt cagaaaaaat
    24001 cccctttttt ctacaaacaa accctaataa tataataaaa actgttgaag tgattgcact
    24061 gacaatcgac atatctgtca aagtcgatcg aaaaatgtca aataagttca tctttctcct
    24121 cctaattatg ttcatttatt cacaataaaa aaagctttta ttttgctaat acgtattaac
    24181 atttttaatt ttatctttac attgttactt attgaacaat aggaaattaa agaaactttt
    24241 gaaacttatg taaagtgatt tttactagaa cacaaaaaaa accttaaaac caaacttaag
    24301 aagtttagtt ttaaggttaa cttaaattat attatgcgtg gaaacgttcc acgccatcta
    24361 gataagttgc ttccaatgtc atatcagggt tcaatacgat aaagtctgca tcgcgtcctt
    24421 gagcgatttt tccacatgta tcatcgattt tacagctgat tgctggaatc agactagcca
    24481 tcatgactgc ttgttctggt gttgctaatc cccagtctac aacattttta attgcttctt
    24541 tcaatttcaa tatacttcca gctaagttgc cagattctag acgtgctgtt ccttctttta
    24601 ctactactgg aaattcgcct aaattgtaat ttccatcagg catcccaccg gccatcatac
    24661 agtctgtaat taatgcgaca tgatcatgtc ctgctttttc cattaggatt cccgcagcat
    24721 ttggatgtac atgatggcca tcacaaatca attcagaaaa gacatgttct aaagataata
    24781 acgcacccac catacctggt tcgcgatgat tcaatccacg cataccattg aaagcatgga
    24841 caaatacact tgcgcctgct tcaacagctt tttgcgcttc ttctagtgta gcattactgt
    24901 gtcctagaga aacaactact ccttcttcag tcacttgttt gacaaactct tctacacctt
    24961 gacgttccgg tgctaaagca atttttttga ttaaaccacc tgaagcttct tgccattcat
    25021 ggaaagtatc caaatcagga tccccgaaat aacttgggtt ttgtgcccct ttgtgttctt
    25081 ctgtgaagaa aggaccttca aaatagattc ctttgatttt agctcctggt gcttcctgat
    25141 acattttgcc gattgtctca gctacatctt ttaaacgttc tttgcttgac gtcaatgttg
    25201 ttggtaaaaa tgaagtcact ccacaagata acagaccttc agacatcact ttgatgcctt
    25261 ctgcatcatt atccattaca tcatgattca tatagccgtg aatatgtgta tctaccaaac
    25321 caggagcaat ccatttgccg ctttggtcaa tgatgttgac ttctccctca ggtagttctt
    25381 tggtgtattc accaaaaagt ccatcggtaa tttcaagata gcctgcatgt ttgacacctg
    25441 acgctaaaaa gaatttgtca gcatagataa aagttctcat tctattctct ccctttgttt
    25501 ttctacctct aaagtactct tatttagaga agaagtcaag aatggtctac accatttaca
    25561 aattttttga aatttgtttc acagcttgtg ctaagccttc atagaatgct gctctttctg
    25621 gttcttcttt acgcttgtat attaagcttt taagcacaaa taaatcattg aggtaatagt
    25681 agctattctt ctcttgagcc caatagattc cttgattcac ctgttctaac gcttcgtcga
    25741 tttcattttg atggaataag aaatttccat aattataaaa aatttgcgaa aattcacttt
    25801 ttgatcgttc atcagctgat tgatgcagca gttggatgct tcgactcaaa tagtagcgtg
    25861 cttcagccgt ttttcctgcc acaccatata tttttccgat acaactaatc agttgtattt
    25921 ctgtgtcaga aacatggatt ctttcttttt ggctagagta gcttaatgct tctttcaaat
    25981 aataaaggga ctgagagata ttttgacgca acgtgaattc gcaaacaccg agataataat
    26041 aatagcgttg aaagtcagtt gcttgataca gattttcaga aatatcagaa gattttagta
    26101 cttgttctaa cttccgataa tcacgttttt ggaaacaact atccaacagt tcaaataatt
    26161 tatcgtttgt ccgagtagtt tttcgagaga gattcatcac atgatcaatc gttaccccta
    26221 gccgttgaca aatctgcatc atcaccaata cattcggcag ttcctcatta ttttcgatcc
    26281 gacttaatac actttgtgaa caaatatcat gcgaaagcat tttttgcgtc attttttgtt
    26341 cttttcgaat ctctttaatg atcgttccaa aggactcgat taacgtttcc ataagtatcc
    26401 tccccaaaat atgcgtattc gcattctatt cgtattttac tttaggaagt cgcaaacttc
    26461 aagaaaagac ttgcaactaa ataatatact ttagttattt aagaaaactc cactagaaag
    26521 agagcctcag tgtgtttgtc tgtggccctc ctactgaaaa atttggtttt taaaatcatt
    26581 tttggcgata ggttgctagg aattctctca ttttcttagc tgtttgtttc aaatcatcca
    26641 ttttaggaag ataaacgatt cgaaaatgat ctggctggtt ccaattaaat ccaccaccat
    26701 gtacaagtag aatatgatgt tcatgtaaaa agtccaaaac gaatttttca tcatccaaaa
    26761 tattgaatcg ctttgtatca atttttggga atatataaaa agcagctttt ggttttacgg
    26821 ctgaaagacc aggaatatca ttgattgcat tatagatata ttctctttgt tcatagatcc
    26881 ttccgcctgg caggagcagc tcatcgacac tttgataacc gcctagcgcg gtttggataa
    26941 tttgctgaga caatacattg gaacacaaac gcatggagga caacatattc agcccttcta
    27001 tatagccttt gacgtgtgac ttatctccac ttaggaccat ccagcctact cgaaatcctg
    27061 ctacacgatg agatttggat agaccgttca gcgtaacaac gaacaaatca ggcgctaatg
    27121 tagcaatcgg aatatgttct agaccatcca tcactaagcg atcatagatt tcgtcggaat
    27181 aaataatcag gttattttgt cgagctactt caacgatttc ttctaataat tcttttggat
    27241 aaagtgcccc agtaggatta ttaggattaa tgataacaat agcttttgtc cgactcgtta
    27301 tttttgattt gatatcatca atatcaggat accattctgc ctcttcatcg caaatataat
    27361 gaacaggtgt gcctccagct aatgcaatag aagccgtcca caacggatag tccggcattg
    27421 gaaccagtac ttcatctcca ttgtccagca acccctgcat acacatcgtg atcaattcgc
    27481 tcactccgtt gccggtgtag atatcattga tcgtcacatt cggaaaatgt ttcagttggc
    27541 aatattgctc aattgctttt ctagcagaaa agatcccctt ggaatctgag tagccttctg
    27601 agtcacgggc attcatgatc aaatcacgaa tgacttcgtt tggtgcttca aatccaaaag
    27661 gtgcgggatt tcccgtgttc aattttaaaa tactaatgcc ctcttcttgc atccgctccg
    27721 cttcttctag aacgggaccg cgaacatcgt aactgacacc ttctaatttg ttggattttt
    27781 caaattctct catcacttag ccaatccctc atttcaaaaa gttagaactt tccaaatttt
    27841 ttgttattta ctatttcaat atcatactcc atcctagaaa attttgccac ttatttagga
    27901 aaaacgtaag tattaaaaaa acacaaacaa gcgttgagaa cttaattgtc atgatagtca
    27961 ttccatagat tcgctgccca atccattgca attccacaaa tgattcctag cataaaacca
    28021 agcaaaaaac gtccgaatgc aagtccaatc aatacaccta agatcattcc cagtcctgaa
    28081 aattctccgt catatttctc catcttaata agtcctccca tttttgagct tgacaactat
    28141 gtaaaacctc gctatcatta gtgtgttatt attacgcaga tgtgttggaa ttggcagaca
    28201 agcatgattg agggtcatgt gagcgttagc tcgtgtgggt tcgagtccca tcatctgcac
    28261 tacaactcgt gaagttaatt ttgcttcacg agtttttttg tttgaacgtt tctttatgcc
    28321 attatataca tatcactgta tcctttacaa aaagaacgta caatcatgta aacagcctga
    28381 ggtgagtata tgaaggtcgg aaacaagcta ctcgtagaaa cttgcaagtg ttaaaacaat
    28441 taatcgaaaa acgagtaaaa tccctcacct aatactaaag cgagggattt tttgtatatt
    28501 atctgtttat caccgttatt ataaaggtac aaataccaag cacggttaat ccaaattgca
    28561 taaattcatt tttttgtaca ctcatgcttt tcattagctc tttaactgcc attagtacta
    28621 agatggcgat aacaacataa agtatatagt acgtccgcat tccggaagcc catactgtgg
    28681 gagaaaatcc cataattaac cttgaacaaa atcccattat catcaaaata actaaaaaaa
    28741 tagaagtttt cttattgtca aaacttaaat aaattccaac aattaaacat agtaataatg
    28801 ccaagactac taaagtagct atccaagtac ctggataaaa aagtgacagt ttcgttccta
    28861 actctgtaaa gagattattc aggttactac tactccaaat cattgccctt ttatttccat
    28921 tgacgtaagt aaagctttga cccattgtat taccaaaata aataatcagg tttaagaaaa
    28981 acggtaatgc agtcaatata cgcacataat agttttgaca tttcctatat gttagaagga
    29041 aaattaagaa aaatagcaat aaaaataaga tattcatgtc taaaaaaaac ggctttccaa
    29101 atgatgaaat acctaaatct aacttattaa gaaagttgaa atttttatat tcaggaaacc
    29161 atttattaat ttcatgtgca gcacgtaatg cattccctgg agttgtcaaa gagaaaatta
    29221 attctgctaa gcttattatt gaaaatactg ataacttata attatatcgt ccattgacaa
    29281 tcaaatataa actaactata cttgttagaa caaaaaaaca ggcgttgact tgttcttgat
    29341 tagttaaaaa tatcaataaa ggaatactta cccaatatat ttttctattt atttcttctc
    29401 ctcttaagag ttgaaaaaac ggataaaaag ttagtaaact aaatgctact ggccactgat
    29461 agttcaaggt ggttgctctc caaccggttt cccccattac tgtcaatggt attaaacagt
    29521 atatagagca aaccaataat aaatttttaa catttatttt ctcaaaaaca ta
//
LOCUS       DAIGUC010000037        29107 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.037, whole genome shotgun sequence.
ACCESSION   DAIGUC010000037 DAIGUC010000000
VERSION     DAIGUC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.037"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..1030)
                     /locus_tag="NOB46_001739"
     CDS             complement(<1..1030)
                     /locus_tag="NOB46_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1058671.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="NOB46_001740"
     CDS             complement(1112..1801)
                     /locus_tag="NOB46_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI1058672.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB46_001741"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB46_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCI1058673.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="NOB46_001742"
     CDS             complement(2328..2831)
                     /locus_tag="NOB46_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCI1058674.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB46_001743"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB46_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCI1058675.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB46_001744"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB46_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCI1058676.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB46_001745"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB46_001745"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HCI1058677.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB46_001746"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB46_001746"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HCI1058678.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="NOB46_001747"
     CDS             complement(6443..7462)
                     /locus_tag="NOB46_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI1058679.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="NOB46_001748"
     CDS             complement(7635..8540)
                     /locus_tag="NOB46_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI1058680.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB46_001749"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB46_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCI1058681.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB46_001750"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB46_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCI1058682.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB46_001751"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB46_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI1058683.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="NOB46_001752"
     CDS             9753..10397
                     /locus_tag="NOB46_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1058684.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="NOB46_001753"
     CDS             complement(10453..10956)
                     /locus_tag="NOB46_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI1058685.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="NOB46_001754"
     CDS             11553..12518
                     /locus_tag="NOB46_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI1058686.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="NOB46_001755"
     CDS             complement(12617..13789)
                     /locus_tag="NOB46_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058687.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="NOB46_001756"
     CDS             complement(13776..14921)
                     /locus_tag="NOB46_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058688.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="NOB46_001757"
     CDS             complement(14935..15867)
                     /locus_tag="NOB46_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058689.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="NOB46_001758"
     CDS             15984..17063
                     /locus_tag="NOB46_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI1058690.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="NOB46_001759"
     CDS             17060..17689
                     /locus_tag="NOB46_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1058691.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="NOB46_001760"
     CDS             complement(17799..18026)
                     /locus_tag="NOB46_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1058692.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="NOB46_001761"
     CDS             complement(18129..20717)
                     /locus_tag="NOB46_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCI1058693.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="NOB46_001762"
     CDS             complement(20737..21396)
                     /locus_tag="NOB46_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1058694.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="NOB46_001763"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="NOB46_001763"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCI1058695.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="NOB46_001764"
     CDS             complement(22169..23035)
                     /locus_tag="NOB46_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI1058696.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="NOB46_001765"
     CDS             23144..23785
                     /locus_tag="NOB46_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCI1058697.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="NOB46_001766"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="NOB46_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCI1058698.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="NOB46_001767"
     CDS             complement(25226..26125)
                     /locus_tag="NOB46_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI1058699.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="NOB46_001768"
     CDS             complement(26127..26924)
                     /locus_tag="NOB46_001768"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HCI1058700.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="NOB46_001769"
     CDS             complement(26902..27606)
                     /locus_tag="NOB46_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCI1058701.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="NOB46_001770"
     CDS             27737..28312
                     /locus_tag="NOB46_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HCI1058702.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="NOB46_001771"
     CDS             28430..29107
                     /locus_tag="NOB46_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI1058703.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6169 c         5232 g         9143 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaa
//
LOCUS       DAIGUC010000038        27885 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.038, whole genome shotgun sequence.
ACCESSION   DAIGUC010000038 DAIGUC010000000
VERSION     DAIGUC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.038"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(976..1149)
                     /locus_tag="NOB46_001772"
     CDS             complement(976..1149)
                     /locus_tag="NOB46_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058704.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1152..1550)
                     /locus_tag="NOB46_001773"
     CDS             complement(1152..1550)
                     /locus_tag="NOB46_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058705.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1766..2821
                     /locus_tag="NOB46_001774"
     CDS             1766..2821
                     /locus_tag="NOB46_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HCI1058706.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2841..3194
                     /locus_tag="NOB46_001775"
     CDS             2841..3194
                     /locus_tag="NOB46_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058707.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3376..3672)
                     /locus_tag="NOB46_001776"
     CDS             complement(3376..3672)
                     /locus_tag="NOB46_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058708.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3676..4494)
                     /locus_tag="NOB46_001777"
     CDS             complement(3676..4494)
                     /locus_tag="NOB46_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1058709.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4720..4941
                     /locus_tag="NOB46_001778"
     CDS             4720..4941
                     /locus_tag="NOB46_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCI1058710.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            4943..5209
                     /locus_tag="NOB46_001779"
     CDS             4943..5209
                     /locus_tag="NOB46_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1058711.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5322..5861
                     /locus_tag="NOB46_001780"
     CDS             5322..5861
                     /locus_tag="NOB46_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058712.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGAYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKQQLDRIKEENNKPNLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
     gene            6355..6639
                     /locus_tag="NOB46_001781"
     CDS             6355..6639
                     /locus_tag="NOB46_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058713.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6913..7167
                     /locus_tag="NOB46_001782"
     CDS             6913..7167
                     /locus_tag="NOB46_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058714.1"
                     /translation="MNYTDEEQITLEYVFTNEKGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            7249..7434
                     /locus_tag="NOB46_001783"
     CDS             7249..7434
                     /locus_tag="NOB46_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HCI1058715.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            7501..7896
                     /locus_tag="NOB46_001784"
     CDS             7501..7896
                     /locus_tag="NOB46_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCI1058716.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEDLLEK"
     gene            7886..8263
                     /locus_tag="NOB46_001785"
     CDS             7886..8263
                     /locus_tag="NOB46_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058717.1"
                     /translation="MKSKKETEPMKSTHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            8285..8659
                     /locus_tag="NOB46_001786"
     CDS             8285..8659
                     /locus_tag="NOB46_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058718.1"
                     /translation="MKQTQTEPINDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
     gene            complement(8965..9363)
                     /locus_tag="NOB46_001787"
     CDS             complement(8965..9363)
                     /locus_tag="NOB46_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCI1058719.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(9553..10320)
                     /locus_tag="NOB46_001788"
     CDS             complement(9553..10320)
                     /locus_tag="NOB46_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1058720.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFKDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            complement(10355..11578)
                     /locus_tag="NOB46_001789"
     CDS             complement(10355..11578)
                     /locus_tag="NOB46_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCI1058721.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            12559..13362
                     /locus_tag="NOB46_001790"
     CDS             12559..13362
                     /locus_tag="NOB46_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1058722.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            13947..14402
                     /locus_tag="NOB46_001791"
     CDS             13947..14402
                     /locus_tag="NOB46_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058723.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            14521..15579
                     /locus_tag="NOB46_001792"
     CDS             14521..15579
                     /locus_tag="NOB46_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HCI1058724.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            15621..17570
                     /locus_tag="NOB46_001793"
     CDS             15621..17570
                     /locus_tag="NOB46_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCI1058725.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            17573..21214
                     /locus_tag="NOB46_001794"
     CDS             17573..21214
                     /locus_tag="NOB46_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058726.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            21614..21952
                     /locus_tag="NOB46_001795"
     CDS             21614..21952
                     /locus_tag="NOB46_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058727.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            22062..22283
                     /locus_tag="NOB46_001796"
     CDS             22062..22283
                     /locus_tag="NOB46_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058728.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            22303..24459
                     /locus_tag="NOB46_001797"
     CDS             22303..24459
                     /locus_tag="NOB46_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058729.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            24471..24704
                     /locus_tag="NOB46_001798"
     CDS             24471..24704
                     /locus_tag="NOB46_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1058730.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            24694..25560
                     /locus_tag="NOB46_001799"
     CDS             24694..25560
                     /locus_tag="NOB46_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058731.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            25575..27545
                     /locus_tag="NOB46_001800"
     CDS             25575..27545
                     /locus_tag="NOB46_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058732.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            27712..>27885
                     /locus_tag="NOB46_001801"
     CDS             27712..>27885
                     /locus_tag="NOB46_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058733.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARV"
BASE COUNT         9994 a         4257 c         5010 g         8624 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac ctcgagtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgatcaagt ttttacctat tcccaaaatc catttattcg ttattttttc cactgattaa
      181 gaataattat ttgatgctta aattagctaa aaaagcgatt tgttactgat ataatcatga
      241 tattgcagct gaattaggcg gaaagataaa atgttcgcaa aatcaaagta tcaattatct
      301 tgttttttta taaatttgta agtaaaaatc taaaaaagtt ttcttttaat tggtatatgt
      361 attaaaatca catttaatca cccataaagt atgcgctttc atttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaatcattt attatgctct tttataagga tattaattga
      481 tctaatttga aaaaaatcaa aatttaaatg ttttaatatt acaaataaaa tcatgttatt
      541 gtaaaatggt ataaaaaagc taaatattct atttttgtta ttttattagc aggaaaattt
      601 aaatagtttt acaagaatcc gtagaaatat attggttttg ccttcagatc aatactggat
      661 catattaatc tgaatataat atatgaacta acaaatagct taacctcgct attttgtttt
      721 ttctgatcac tatctataca gcattagtaa atagaatttt aaaaataaaa aaattaagac
      781 aaaaaagtat caacataaac atatacatat acacgtttat gttgattcac ttaatttgtc
      841 ctttaaaaag cacttatttt aatataatgt tattttataa tcttattaca agctgattgt
      901 taggcgttgt cctttcatta catttattaa cggttatttt attgtttaat ttattaatta
      961 tttttgatct aaaacttagc ttaacaaata aataattaac caaccgccag ataaaaatgc
     1021 gatcattgct aatacataag caaagataaa aatatgttcg atcagcttaa accctgatgc
     1081 gattaagcag accaagtaaa atagaaattc tcttacagat aatggtaatt ttctaactag
     1141 catactcata attaacaccc caaagtaata ttgtattttg aacattttac atccaataca
     1201 gcatcaatca accattgcca atcaaaaata caaggcttca ttgaagtatg tttttcagat
     1261 gaaaagatat aatataattt cttcggaata atattttcag ttgttgggat caagctaaat
     1321 ctaataccgt ctaactcata gctaccagct ttctctccat taaaaatttc cttagcactt
     1381 tcttctaaag aatcaaaata tttttcgaca gcaatctttg aagcttttac tattgaagca
     1441 tttccctttt cgataaaatc tgcttttgtt ttaccgacaa taagtaattc ttgatcagta
     1501 aaatcttcta aaataatggt agtgtaattc ttatttcttc tcaatcgcat caggatcact
     1561 ccttaatata atttatgttt ttataatatc ataataagat aaatttgcaa gcatttattt
     1621 acaccttttt atttacactt tattataatt aattagactt ttatgattgc atttttttct
     1681 tataaacagt tgcaactaat agtaaatagg tgtaaactat tttcgtaccg aaataccata
     1741 aacacaaaca gaaagaggtc ataccatgaa agaaccatta ttgttttccg ttgacttagg
     1801 gaataaatca gtaaaagaaa tgagtacaca cgtttctcca ctctcacttc cctctcgtat
     1861 tttgaacaaa aatatcatta attcaggacg tttttctaat ataggttcct cattaaaacg
     1921 atcactaaac gtttctgaat atagcctagt aaacactact gaaagctatt actttgggaa
     1981 ggatatacac gagctaggaa aagatgacta cgtgatagaa tcactaggtt ttgggatcag
     2041 cagatacaag caggaaacct accaaaatat cctatctttc tctttagcta acctagcacg
     2101 tttagaagat caatctgatg acgttttaac cgctaatcta gttttaggtc tgccttcatc
     2161 cgactatacc gaaacaatcg tcaaatacgt gatgcaacaa gccacacgac aacattcagt
     2221 tgaagttgac ggtaaagctt ataatataaa cgtagatacc gtttgggtac tgccacagcc
     2281 gattggaaca ctatataacc tcctacttgc tgatgatggt agtgtacaag atgaaacatt
     2341 gatcagtcag aagatcggtt ttgttgatat tggcggtggc acgaaacttt ttgatgttgt
     2401 ccaaaatttt gaaattgacg aaaacaatcg tgaacaaaag gataccggca tttttacttt
     2461 atataatcgt atcgtaaata tgcttgacct tccgatcagt cctaatgctt tccaacttga
     2521 aaagattatc cgagaaggca aagaaaaagg cgtatatcta tttaagccaa gcggaaatga
     2581 aagttttgat atttcagaag tagttgaaag agaaataaaa acatacacca atatggttgt
     2641 tgcagaagtt ttagctacat tcaaaaactt cacaacctta gataaagttg tctttactgg
     2701 tggtggagct tctattatcg acaaacaact tgtaaaagat aaaattccgc ataccttgtt
     2761 tgttgaagac agtgaatttt ctaatgtaaa aggcttttac aagtttggtt taactcaata
     2821 aaacagcgaa ggagatcaac atgaataagg gaaaatcaga gcgttatgta gttataatca
     2881 atagagaaaa ggttagcgag ttacctttag cagagtttct tgaatccgaa tatgaaacac
     2941 taggcgttaa atactctcag acgatcaaaa aagctttgaa cctatatcgg cgtgtaaaga
     3001 acaatgaagt tacaattatt gaagcaggca acgatagaaa cgatagcaaa gtagcagaag
     3061 taaagaataa accaactgat cataacccta ttcaacaaga gcatccttca acggttacat
     3121 ccgatcattc agcaaagaaa gaaaagccaa tgctgaaagg gttcaatgca ccaagtaaca
     3181 aagacttact ttaaaaataa aaaggcgagg ttacaatacc tagccttttt attatgtaca
     3241 aatataaaca taaacatata cgtatacatg tatataaaca tgtatacgta tatatccata
     3301 aacacgtata ttaaatttag ttaagctata cctaaccgct tattccaata aaaaaagtga
     3361 tcagctttaa actgatcact caccaaaaac ttcatcatac aagttatcta tcatttcacc
     3421 aagtaaagct gaatctgatc gaattcctaa cttttcgctg attttagata gtttctttct
     3481 ttgcgatggt tgaagcgtga attgataatt tttcttcttt tcagaactat cactttttag
     3541 tttagctacc aaagaacttg ttgtttcttt aggtgtttgt ttaggttctt caactgcttc
     3601 aaccacttca ggaacttctt ctacttcagc ttcagcgaat tttttaaatc tattttcttt
     3661 cacttcaatc actccttatt cttgtgccgt atcaattatt ttgttgtata gcgtaaacgt
     3721 gctttcaaag aaatccttat tcttacgata gatattctta tccttagcga actcagcaat
     3781 attcttacct tctaagctag ttgcattaag caattccttc tcttgtacat atccaagata
     3841 attagataac gttggtacca gttctaggaa ctcacgactt gaattagtat tatgtttgat
     3901 cctgctaccg atcgtagcgt atttagtttc catcagtgtt tcaccagtct taatatcaat
     3961 caactgtttt gctagtgcat caatatcttt accaagcttc agcaaagctt caaaaccatc
     4021 tttagatgga tcagaaatgc ctacgacaag atcagataca gcccaagcat tttgagctag
     4081 tagacctgca tcattatgag tatcaatcag aattagatca tacttctctt taagctgttc
     4141 atagttaaca accatccatc taaacagtag ggttctgttg ttaggcatat cacgcatttg
     4201 catctcaact tgttttaaat cttcacctgc tactaaaata tccatgttct catttacagc
     4261 taaaggttca gctgatccat gaagatataa atgattgatt gtattctctc ttttcgcttt
     4321 actgaaagca tcaggaaatc gttttgatag gttttgcgac ttatcttcat caatatacag
     4381 caccttcata cctaaatttt cgacagcata tccacctaga ttgtagattg ttgttgtttt
     4441 acctgttcca cctttttcaa tgtttccagt aatgattgac aacttctttt ccatgattaa
     4501 acctccctta ttaacctttt gtaactccat tatacactat aaacacgttt atgtatatgt
     4561 ttatatacat aaacgtgttt atatttatat ttgcttttat attctacaac ataaacatat
     4621 atatgtatat gtttatgttt atgtatatat tcatatatat aactattgca tttgtcatac
     4681 aatcgtagta caatgtaatt gaaaaggagt tgataaacta tgccagtaat aagtattcgt
     4741 gtatctaaag aagaaaaaga ttttcttgaa aaagttgctg aattcaacgg agataacatt
     4801 tctgaattta tgcgtagtaa ttccctgcaa acagcagaaa cgttagtaga ctttgccacc
     4861 tacaaggaac taatgaaaga gcatgaggaa aacgatcaaa gtatttccca cgaagatatg
     4921 ctaaaagagt taggcttata agatgactta ccaagtaaga tatgaacgtg aagctcaaaa
     4981 agcgctaaaa aaaatggata agtttcaggc aaaggttatc ctaaactgga tcgagaaaaa
     5041 tcttgtaggc actgatgatc caagaaaaca tggtaaaggt ctaacagcta ataaatcagg
     5101 ctactggcga tatagggtag gtgcctaccg tataatagct gatattagcg agcatgaagt
     5161 gacaattctt atattgtcta ttggtcacag aagtgaagtt tataagtaac agacaagctg
     5221 ataaggcttg tctgtttttt tgttaaccca acaaaatcac tgtttacgat cccactttac
     5281 ctaaaaaaga acaataccct cttgttatta tacacactgg tgtgtataat ataagtgtaa
     5341 acaagctaat taactttcaa aaggagcgat tttttatggg atggtatggt gcttattcat
     5401 cagcaaatga agtgatcgaa gaaaagaaag ggtacgccaa aaatggtttg gaaatcgtag
     5461 ataccaaagt aacgaagacc tatggtatta tccttttcaa agatgcagaa ggaacctacg
     5521 atattgacag cttcatcttt cgagatgaaa tgtacaaacc aatctacttc ttaaatgaca
     5581 gtcctgctta ctttaagaaa attccgaaaa aatggttgaa attctttgtc ggtgatcaag
     5641 aaaaaatggt taagcaacaa ctagatagaa ttaaagaaga aaacaataaa ccaaaccttg
     5701 atgacttatt agttgcaggt aaaacttact caatctggga tggatcgtat gtcgctgttt
     5761 atcagtataa actcaaacgt agctttattt ttagactaca agatggatca ctcactcggt
     5821 tcactcgact atcagcagga gatgttaagg aagtagccta aaacttaaat acataaacat
     5881 aaacgtgtat acgtttatgt ttatgtttat gtatatgtat atgaatataa acgtattagg
     5941 tacgaacgtt tttaaatgct tttctgggct ttgattttag ggtagggcta aaacatccat
     6001 tgatccaaaa cagctcagaa acgcatttaa acgtatctga taccaatatt acagaaggag
     6061 tgtatcgtat gattaaccta tttcttttag tgacagctag tacattattc tttactggaa
     6121 tatcactgat aatttcctat ttgatctata agaaagccga aacttacaca agcaaagcaa
     6181 ccggactagc cgtttcctcc tttttaactt tgctgacttt ttttgttact ctatcgtttt
     6241 cttttgttta gcacagctga tccatcagca aaaaacctct ctttacatta tacacactag
     6301 tgtgtataat gtaattgtaa acaagctaat taacttttag gaaggagtga caatatgcta
     6361 acagctacat tacagcaacc tactcacgtt gctattgcag aaagctatac aattaatgca
     6421 ggggtcgtta aacagctgat caaggatcga gaattcaaaa agtttaacag tcgtcaagcg
     6481 tataacagac agttaaagaa agctattcta aagcacaaaa attccttcat agggaaattg
     6541 gaaagtgtgg atgttaaaac tgtttcaacg gcattttcag ttgttgaagt gactattgac
     6601 ggtcgcttga tttctctatt tgcttttgga attaattgat agggagtgtg gactttggaa
     6661 ggtaagactt ttgcagaaat ttggactgaa tttattgagg taccaactcg cattgatccg
     6721 ataacttctg aaaaggtatt ggatgcagac ttctacaatc tcaaagcagg tactagcctt
     6781 gaatgcgttt agatgtattt agaagagcat ttcaaaggcg taacgctcgg tcacgtctta
     6841 taccacaatg gtgccgagtg ggatgcaatt ggaaatatcc atttttctta atacaagaaa
     6901 ggagaacaca atatgaatta taccgatgaa gaacaaatca ctttggaata cgttttcaca
     6961 aatgaaaaag gggaggaaat tgaaaaagtc ttgatcattt catcaaaaga cttggagaac
     7021 gctttgactt atgaaccata cgaatcaacc gtaactgtca atgaattctt agatacctat
     7081 acttctaatg atacttggga aattatgaat atttgcaacg ctaataacat tcaatttgct
     7141 gaaaaaacca ataaatcatt ttattagttt tgcaataaaa catcctcttt ttctattgat
     7201 tccatacaca acaatgtgta taatagattt tgtaaaggga gggtagctat gcctaagaca
     7261 gcaagagaaa ttgtaaaaat tctcaaatct aacggcttca aaaagactgg acaaactggc
     7321 agtcatgcaa aattttataa ttccaagact aaaagaacgg tcgttgttcc gatccacaat
     7381 ggtgatgtac cactaggaac agaagctaat atctggaagc aagcagggct ttaacagcct
     7441 tgccttccta tttggtatta ggcatactat cctctcttac actagaaaag gagcgaggaa
     7501 atgaagacaa aaaatatttt ttatccggca atcttcgaga aagaaggaga agcttataac
     7561 atcgttttcc ctgacttacc ggaaatatct acctttggaa atagtcttga agaagcatat
     7621 ttaaacgcta aggatgcttt aggattagcg ctatatagtg taccagatgc agaatttcct
     7681 aaaccatcag cagtggaaga attaactttg aaagccaatc aagtagtagt aatcatccaa
     7741 ctaaacatta aacttttccg aagaagctta aatacaaaaa caattagaaa aaatgttagt
     7801 gttccggaat ggttagttct tttagggaag gagaaaaaca taaacttctc tcaattactt
     7861 caaaaagcac tagaagaaga cttgcttgaa aagtaaaaag gagaccgaac ctatgaaatc
     7921 tacacactta aactatttct ctcgaacgtt aatcaataat ctattaaaag atacaactgg
     7981 cattagcgtt agtaccaaac actttgccaa tgatctaatt atttttgagg ataataactt
     8041 gcgaattgag atgtttattg aacaggcaac tcctaactca atacctgaat tctgctatac
     8101 gcacactgaa aaaatgaaac atgcaaaatc agttaaagat gttgaagcat taagtgaatc
     8161 actaacgaac gctttaaacc tcgttaagaa ggctaaattg ttatttgaat ttcaaaccga
     8221 ctaccacaat gagttgcttg ctcaatctga aattttagat taattgaaac aggagaagag
     8281 aaagatgaaa caaacacaaa cagaacccat taacgatacg cttgctgatc aattagcagg
     8341 ttattataaa ttatttgaga tgagtaaagc acagcgcttg atccactatc tttggaaata
     8401 caaaattttg tttctttttt gggaagcaac actaacattc tcagttcttt tttataagtc
     8461 agatttttat aatcaacact tagttttagg gagttttttg cttatctaca ccattttgat
     8521 gcttaattta tatacctaca tcacacttga agaacactta gtaattagcg atgcagggat
     8581 cgagagaaac atcaaaaggg tatctttcaa gatcacgtta aacaagccta ccgataaaaa
     8641 gctctcagaa gcgttctgag agcttttgac attttcttgt ataatttatc ctaacacatt
     8701 acaaagcacc taattcgagc ttatatcaag caaatttgct atttattcct caatacatat
     8761 ctaaaaatta cttgatggaa aactagatac atggtaagca tgaaaagaaa atcaatttga
     8821 gcagatgcag tataatacat agcaatttaa aagctctcag aacgcttctg agagctttta
     8881 atatattctt tgataatttg tctttcttaa atccatacgt cctaaaacaa gctgtttttg
     8941 cttaatatga tcatctgaga gacatcaaat caacttttct ctcaacaaat cattcaaagc
     9001 tttcgacaga ttaatattct cttcagccgc taaaacattt aaatagtgtt ccacagtcac
     9061 tgattttcga tcataatttt gcttgtttcg agctttagca actttcgtat tagcttttac
     9121 gacaaataaa ttaacattct cagatcgctt gattcttgca tttaactctt gaacaggcgt
     9181 aggcgatgga atttcttttt cttgcaactc taaaagcacc aagtatcctt ccaatacttc
     9241 ttgcgccatc tcaaaagcat cttctaaagt ttcaccatgc gtatataagt ctggaaaatc
     9301 tgggaattta actgcatatt catttccttt ccattcgaat actgcacaaa aaaagtattt
     9361 catcgcattg cacctctcta attaaaaaat aatttttgct ttttggtttc aaaaaaagaa
     9421 tcgcctacca aaaaattgat aggcgatcac aagctaatta acctctaaag gagattaata
     9481 ccttgctccc aaggcactac atatcttaac atacgtctga agcatcttca aacgagtaag
     9541 atatattttg cattaaccta attttttttc tctataaggt ttttcatcaa actcactaga
     9601 aatattaaac tggacagcaa aattgtaatt tctgcctttt ctaactttag caaaatcaat
     9661 cttcagcatt gatttttcat taatttcttc aactgattcc cttaaaacac gtctatcaaa
     9721 attcgatatt gttttatact cattttctgt tttcgtaatc tcacgaattt taactatttc
     9781 aatcagggga ttcttatata tttcagcttt ctcaaaatct cctttatttt tggcgataag
     9841 atatttttta taatacatcg ccaaatattt gtataacacg atgctatatt ttttttgaaa
     9901 agatgctaag tctttaaaaa caaagaacgg atacttcttt ttgattgaga caattaaggg
     9961 aattacatct tctgaaaaac tgaaagatac actatgctct tctaaatccc aatgaatccg
    10021 atcaatagca gatacagtag tatacgtctt atatttcttg tctagattcg atatttcata
    10081 aactgcttgt ctttgcaaag tgttaactat ggtttttagt tccgtttcaa gattttgatc
    10141 aacatccatg taattaataa tcgctttaac aggtaaatct actacgcctg ttttctttag
    10201 ctttgtgggt gagatataac tgaacagcaa ttgataaagt tcatacgact ttaaatccat
    10261 tttcatatca attgttgcta agaactcctc attgtacttt gtcagttcat cttttttcaa
    10321 aagtttttcc ttccttcacg cattttttca gttgttaatc ataaaggttc acataaggca
    10381 aataactcgt aattgatttt tcgagatatt taacagtatt ttttattgtg taatcctcct
    10441 tatgagtagc aacgtaagat aggtgattga caactgattc aaatcctcta tctttggata
    10501 aacgatcata aagcggataa actttattct gaagtcggct cataagttta agatcgcata
    10561 agtcggcaga actgatcaaa aagtttttga ttagtaattt agtgtatttg ctattcatag
    10621 ctttcaagta cgattgattc attttctctg ttttatcttc tgcgcctttt aaataagcag
    10681 ggtctctttg ttcttgctta taaggtaccg gaactgacat ggtacgtgta agcaagaact
    10741 ttatgtttgt ataagtatga cccttcttga taagctcata gtcaatttta aaatcagtgt
    10801 atttattcag ttgggcaatc ggttctttaa ttacacgtct ttcaaagtct cgaaaagctt
    10861 tatatttttt ctcaatacta aatttctttc gtaaatctgc aatggagaaa acaggatttt
    10921 ttaatctatc aagtgatttt gtactccatg ttaagttatc tctatttgct tcatacagat
    10981 taaaatcttt agtgaataat tgaaaaaaac tgatcgcata cttgcttgtc aagttaacta
    11041 cttgatcaaa tgtatattgc gtaaaatgat cttctaagtt cgttaataaa ggcataattg
    11101 aactactaaa tttaatagat actgcatcag aaaaatcatt gaattcagta atttctagcg
    11161 gtgagatgac tttgtattca gtcttaccgt taggtttagt tctttgaatt ttaatgacag
    11221 attgctgatg caatttttca ataacttgtt ttaatcttga atgttttgaa gaagatgaac
    11281 tagaagacat caacgcaaat aaagcctttt tagatacttt gacggtatta ttaaaaggcg
    11341 gatttttagg gtcaagatgt cctatagcgt aaagataaat tttttgtggc atagcatcca
    11401 tttcaacaat gctatctaca agttgattcg ataaagtaac agttaaatca aactttttta
    11461 gattgctttc ggtagtttca aatttcgggt ttacattctt ttctgttatt ttcatacgat
    11521 tgcctcttct ttctaagctt ggtacgagct taaaaacttg gaactggtac gattccattg
    11581 aataagtata gacctgtttt cgatacgtta caataagaaa tgtatcgtaa atttataaca
    11641 taactcaatg tcagtaaaac acattttatt ttttccaatc aaatttcatt gaaaatacag
    11701 cagaaatcgc tattttagaa cattttcaaa ataaaaatcc ttttcaataa aatacgaaat
    11761 tataaaaatt accaaaatta aaaaacaaat atttttctag tttttagaaa taaattcaca
    11821 tactttttct ttttttggat atattcggaa taccacatcg ctttttgtcc acgtttgcat
    11881 cgctttttgt ccacattcac atcgcttttt gtccatgttc gcatcgcttt atgtccaccc
    11941 taaaatctat ttaagattga tataaagcct ttttggaggt tgctaaagtt ttaaagatta
    12001 aaatatatat tataaatata aataaaaggg gaagctgaag cttcctcctt ttcctttttt
    12061 tcaattattc aaagttacac aagcaaaata aactcctaga tagtgttagt tttttttaag
    12121 attttttatt tttaagattt tgaaataaga gaggagtaat cctcctttat taaatatctg
    12181 ttaatatatc tgttaaatat ctgttaatat atctgttagg ggaggcttaa tctcttggga
    12241 gagtaagtat taaaggggta taaaggtaac acttttggac agtaaaggta acaaaagtgg
    12301 acagtaaggg taacagtttt ggacagcaaa ggtaacaaaa gtggacattt gaggtatcac
    12361 actaggataa gacgttacct tcggttttct tgatttggaa ggcgaaaaaa tagaaaatta
    12421 gattagtaac aaatctttgt tgactgttac ctttagttgt gatttaattt aggtaacaag
    12481 cagaaaaaat tgtttccttt aattagtacc agattaacat gattaaagga gcgcaaaaag
    12541 aagattggag agtaatcaat gtctcaagaa gttaccgaaa agattattga tagtgatgta
    12601 gatttagtat cagaacaaac aaatgcaatt gtgcgttata acaatggtct gaatacaaca
    12661 gctttgcgag gatttaagcc tgttgaaatg gatgtgtttt gggctatttt atcaaaaatg
    12721 aaacgtcaag gaacagcaga agtaactttt gatttcaacc tctttcgtta tttggtcaaa
    12781 tacgacagaa gagaaaagga cagtttttat tctgtgttaa aagatttgag tgacaaacta
    12841 ggtaatttaa cctaccgttt tgaagattca gacgtctatg aacagctgtg gctttttcaa
    12901 aaattccgga tagataaaca gaaggaaaca gttacaatta aggcaaatga ggaatttgaa
    12961 tttatcttaa actcaattgg caaaaacttt actcgttttg aacttgataa ttttacaaaa
    13021 ctaagaagta gctacacaaa agaattgtat cgtcatctca tgcaatacag aaataaagag
    13081 tggcgaaatg gttattgggt agtcaaagtt gaagatttta gaagagcatt aagtatacct
    13141 tcaagttata gaatgacaaa tattgataaa agaatactag agcaggcgaa agaagaattt
    13201 ttagctcctg atgaaaacgg aatacaggta tttgaaactt ttgattatga aaaaatctat
    13261 gcaaagaaag gaagaagagt tgatcggctc agattcactt ttagtgagcc agaatcaaac
    13321 ttgccaacca tttcaatgca taattggtta gaagaagatt gagaagaagc aggttgtaat
    13381 tttaatacaa cctgcttctt taaaaaagta tgggtaacac ttttggacaa taaatgcaag
    13441 aagttttttt gtaagcaagt ttcagtctaa ataatatttg aaagaatggc taatctatac
    13501 aaattttaac aactatgggt aacacttttg gacaagtcaa gaaaaaaaac aatttttctt
    13561 aatttgttga tcgactaaag gtaacacttt tggacaacac agaataaaaa gtccggtgat
    13621 atcagttttg gtaggaaaca tcttaatatc tttgtgagat tgaaggtaac atttttggac
    13681 aagtcaacta tttgttaaaa gttaatatag agtaattaga taagtttttt cttttcgtct
    13741 gataaatgga taatattagt tattttattg ctaattagtc tttcatgatg actgaaatag
    13801 ctaaaataaa tatctcgttg gataattgct gatactttaa gggatatcta aatttgctga
    13861 ttgatttatt tatgttatta tgatattata ataacataaa tgtgttacgc ccgaacctca
    13921 ttttaaaaaa atgaaggggt gagacaatga atgctattaa ttggcatgaa tttgttaact
    13981 atatggagag cttactagat gatctaaaaa gttttagtat tgctgatgca gtaaagcatg
    14041 ggttaccagt tagtacaacg atgaaattac gaggattgaa aattccagat gaaattatta
    14101 agctgagaac taaaacaatt attgaaaccg caaaagtcgt tgacaatatg aaccatgaac
    14161 taaaaggcaa gaaaacaact tacgagaaag attttgaacg ttttttaaaa tctgttattg
    14221 gaaaatatct aggtaaaaaa tctttcagtg aattgagaga tgaagagatt gtacctactc
    14281 caatggttag caaaatccga aaaaacaaag ccgaggggaa ttactatctt ggtacaatag
    14341 caaaaatcat tgattatttg gaaaataaag agcaaaagaa aggaacgaag aaaggaagat
    14401 aatttttgtg ttaaatatta atggggaaga atataccgaa atgattcaaa atcccgaacc
    14461 tagaattacc gaaaaaacgt ctgattgttt gctcttttat gaaagggggc agacaaacta
    14521 atggaaaaaa acgtcaattc aacatctacc aaagatcaat acagtattat tggagggttg
    14581 cttggtgata aggataagag aacacgtcac ggattacgca ttatgcttgc aacttttcta
    14641 ggagtgcttt ttttattaac aggcttgggt agctacattt atcaattagg aaactataat
    14701 tattatctcg tgaacaatac aacacctata ggctcttcat tggagtttgc tcgatcagga
    14761 gcagagatca ctatttcaga tgtgtggaca gatcaaaaca gagatgtaac agtagtaaaa
    14821 ctcggttact cgcaaaacgc tagaaagttg ttatctacgc aaggaaaaaa ctacaactta
    14881 tatatggcaa cgaaagaaaa agatcgtcct aaaaagcttg aaatgagcta tgggatgtta
    14941 agtactgatg gggatgcttt cttattccta aaaggtaaat tagatgaaag agcttatcaa
    15001 gtttttattg caaaccaagt atcactaatt tctggtgatg atacagctga cgatgatacc
    15061 aaagtcaatg tgaatgaagc agattcagtt acaaaagcac tttctcaata ttctatgaat
    15121 gatgttaata atgaaggagt aatttctttt gggaaaaaag caaaacctgt taatactcct
    15181 gataatatca atttcagaat aaatccatat tcagattcaa ctaatgtcta tcaaggaagc
    15241 tttcttacca aagatggcga tattgattat tcaaaagttg tagcagttac aagtaagaat
    15301 aatgttgtaa gtaagttaga agatcagtta aatgcttcaa atactaacat caagaaaatt
    15361 gaagctacaa aagctgagta tctggaacgt ttacaacaaa atcctgacga taaagattcg
    15421 caagaaagta ttcgtcaact agacagtcga atggagaccg aaattaaagc aatcaatgat
    15481 acacaaaaat tgattgatca atacaaaaat gctgacttta acaaagattc ttttggagac
    15541 atgaagacga catttaagta cctaactctg actgactaga agtaaattat tcttatttta
    15601 gaggaagtga acacaaacag atggaaaata gtaccgagtt ttttaagaat attcaaactg
    15661 aatttaatca tgctctcaca ccaatgaaac caccgaaaca taagttagtg ggacgtgatg
    15721 acgaactcca tgagttgtca ctgatcttga atagaccgga aacaccgcaa gctatcttgt
    15781 taggtgaagc cggaacaggt aaaacagcac ttgcaagtga atgggctgaa agacagcgac
    15841 aagatggaaa gaaagtacaa gtatacaaat tatcaatcgg acaattgcgt gttgggggag
    15901 atgatgtcct ccaaacacgt ttagaaacat taattccaag attgaaagaa tatgagcgaa
    15961 ttttaaaatc tgaggacaaa gaaaatgaat ttgtcctctt cattgacgag tttcataaag
    16021 ttgttagctc ttttggtagt ggcaataaaa ttgggggtga ttcgctaaaa gaaccgttag
    16081 caaatgaatc acttcaattg attaccgcta ctacaagaaa agaatatgaa aactatatca
    16141 aaagagatga tgccttaggg agacggttac aaccgttaga attgaatgaa ctaaaaagcg
    16201 atgttgtcgt cgatattttg agacaatggc taaatacatc ctctgttaaa gatgatcctc
    16261 aggcttcttt taaattatcg caaaggattc ctgatgaatt acttcaagaa atcgtacaag
    16321 caaacaagct ttatcgtgag gatttgtccg aaccggctaa atcaattgcc gtaatggagg
    16381 atttgattgc aaaagatcga gtagacggaa atgcttataa tcgagaaagt ctattgcaaa
    16441 tatttggtaa gtataatatt cagctagatt ctgattttga tatggaaaaa cttcaagagg
    16501 aattaaagtc cataaaaggg caaccgttag cagtttatac tataacaatg ttgtttaaac
    16561 gtatgaagct tggatttgat cgttttaaag gtcgaaagca accaaaagca actgctctgt
    16621 ttacaggatc aacaggggtc ggtaaaactg caatggctaa agccgtggca agaggacttt
    16681 atggcgatga aaataaagtt ctcttagtta atatgccgga ctacaaaaca aaagatgatg
    16741 caatgcgttt tagacgactc ataggtactc atgtaaggca tgatccttct gcgattattg
    16801 tgtgtgatga atatgagaaa gctggtgtag aaacactcga tgccttttta tcaattttag
    16861 atgaaggtag gataagtttt actgaaagag gatgggatga tcgagaagtt cacgacactg
    16921 tttcattgtc aaatacaatt ttatttgcga caacaaatgc aggtgcggag atgttcgatt
    16981 cgttaaacag atatagctca ctatctcgtg ttacaaacaa ggaaaattct aatgaatata
    17041 gcactgaact aaaaagagaa taccgaaaag tcgcatcagg gatcaaacaa gccttgattg
    17101 gtgaaggtct aaagcctgaa gttattaacc gatttggacg aatagttcca ttttgggctt
    17161 tatccgaaca aactcttctg gaaattgctt ataatgaaat gttgaagagt gctgaattag
    17221 tacgaaaaca tttaaatata gatttacgtc ttccacctag gaaagaaaga gtatatggtc
    17281 aaaattttta tgcagacgat ctctccatgc acttagtttt tgacatggct tcacaagagg
    17341 attctaaatc agggggtgca aggaatatct tgcatttagt tgaatctgag tttgaagaag
    17401 cgattactga agcaataatt acttatccaa acgcaaaaat attcgatgtt aagttgagtg
    17461 aagccggagc gtttgaagga aaaggtgatt ctaatgctga aattattgca aagccttccg
    17521 ttgctgaaag taaagaaaac aagattgtat tttcgattgg aggggcgtag ctatgaaatt
    17581 caagaaatat ttactacaaa accttagaat aaaacgatgg gtcgtaagag gtctagttat
    17641 tggaggagta ttagcagtta ctttaggcgc tccttttgga atgaatgatc caactcctga
    17701 caatcaagat agcaaacaag aaacagttat aaataagaac gttgcatatg cggaaagtaa
    17761 accggcagaa caaggaatgt ggacactata tgctcgtatc ctaatgggag ataaagaagt
    17821 taatgatagt gccgctaaaa ctggacaaat gaatttgtta ggacaaggtg gtatcagtgc
    17881 cgatttccct tattctgaca tttctaaaca aggtaattcg attgcagggg gtaatgcagg
    17941 tactcaacta gcatctactt tagcaactta tagttactac ggatatattg aaacagtctc
    18001 aggaaatgct attgccagtc aagcatcatc cattctagga agtattggta ggacgattgg
    18061 tagttttatc ggatcaatta gtttaatcct ttctaatatt gctgaatcca taaatgaact
    18121 ccttggaaaa tttttcatga gtatgaatat attttctctt atggggtggg gagaaggtgg
    18181 atcggatgta tctaatccgg tatctaaagc attaactagc ttgcttaaca atttgggatt
    18241 aaataatgaa ttatttaaag cgatagcaag cttatctatg ctctttttca cagcaatact
    18301 aggttatcaa ggaatgaaat tattgtcgaa agatggtgtt aactcgaagg gattatcacc
    18361 agtacttgaa aaatggattg ttcgtatttt tgtattgttt atattcttac cagtggcagg
    18421 atcgctattg ggagtttata tcaacggcat ccagtcagca aaaaaagatg gagatatacc
    18481 aacaaatgtt gtttctgact acatcattaa cacaagactt tgggcttcta ctcaaaatct
    18541 tgctccatca tctgatactg gtggtgatgt acctgacgga aagcctacat ccgaaatcaa
    18601 gttcgttgat acagattatg aaccatctaa aaaatctgca atgataagag cgatcaatac
    18661 tagcagttat gccagacaaa ataatgatct agattctaat tcagtcggta tggctctatt
    18721 aaaagaatgg tcatcgaatg atactttcaa tattaatact tatgccggtg atgttaatgt
    18781 cgccgaaaat gatgcttata tgggaagagc gcctgctgtt tggacaggct ataatttagg
    18841 ggatggaaaa gaaggaagtg caattaagaa accaaccaat ttaaatggat atatttggtc
    18901 agcaaatcaa aatgtgacag acgacaatcg caagcctgat ggaaaaggaa cagcgcataa
    18961 ctttgatgct actcaacctt ggggcgttgc taacaatgca acttttagca cacagtcggt
    19021 agctttattg ctccaatcgg cacttgatac atcgggagct aagttttatg cgtataatat
    19081 cgctccttca ggaattcaag gcagtgctaa gaatatgtca acagtaaaaa cagaatggcg
    19141 tacagcatcc ttagttggtc atggagctat gggtaagttt ggctcgtggc tagcgatgaa
    19201 cgctgaatca atcgttttag cagttcttta cttagcatgt gcttgggcga tgttcaatgt
    19261 gaatatcgtg aaagcattta aacgtgaatt tattcggatt tgggaagtag ttctaacagg
    19321 atcacttgca tcaggagcag gtgtgatggc aatttcatta ggtgttgtta caacatctct
    19381 gatcggacta caattaccta tctttctgat tacttttatt cgtgcatttg gtgatactgc
    19441 tgtgggattc attcctaata cattagttgg cgatggcgta gcaaatattg ttcgatctgc
    19501 tatgatttta ggtgtaggat atcttttagt ctttaaaaaa ggcgaaaaag taaataattt
    19561 gattaatatg cttattggct taccacttga agtagcgttt gggtttgatg aacgtgctaa
    19621 gttattattt ggtaatagaa atgatgctgt gcgagttgtg gacggcgttt ctaaagcaat
    19681 caagaaaagc caaggagcta aaaatcccta ttatgatggt ggcaacagct cagtaaaaga
    19741 tatggttgca ggaggtcttg gagcagttgg agcgcaaaaa atggctgaac gtttgaacaa
    19801 tatgggagat agcaatgctg atgctaagtc cattgctgat aaagtaattc ctgaaacacc
    19861 agaaggaatg tcattcaacg gtggcggagt tggttccaca atcaataata cctctttcaa
    19921 agatttagtt cgtcaagatc aactacgtaa taactcccaa caatatattg atcatttagg
    19981 acgtatggtt gatgaaaacg gaaactttgt cgatgaaaat ggtgaaatat taaaagatag
    20041 taaatacggt aaagatgcta aaggcaactt tattgacgaa aaagggcgtt tggtcgatga
    20101 agatggaaac cttatagata ctaatggtaa accattggaa gatagtgaag atggtaatat
    20161 tggtatggat agcgaaggac gtttaattga tgaaaaaggt cgcttagtcg atgaagatgg
    20221 aaatcttgtt gacgaaaatg gacgcaggtt gctaaatggt gattttggtc atgatagtaa
    20281 cggacgttta gttgacgaaa aaggtcgttt agttgatgaa gatggaaatc ttgttgatga
    20341 gtttggtaat aaacttggta aacacagcga tggatataat gtgaatggag atttagtcga
    20401 tgaggatggg aatatcattg agacgagaga tgcgcttgtg gcagatcgaa atagagaact
    20461 cgaacaacaa cggcatacgc caattgctgt tgcaattcct gagaatgaag aagacgagat
    20521 tactttagat caaactcatc aagaactgag gaatgaaatg agtggtgagg acgtgtcaga
    20581 cagagtgcat cgagaattag gagatggagc atctggtgaa agtcagtcaa gagagcttaa
    20641 cagcaacttt gataatagtg ctattcggaa tgacacagta cttaaagaca gagaatcgct
    20701 aacaaaagaa acggataaag aacaatcaga tgtgaagaaa aagttcattc ctactcctaa
    20761 tgttaatcaa acagataaat atgaaacaaa tattggatca ggaatgtcga aagacaatca
    20821 atcaattaga gaacctgaac tgacaaataa aaataataga acaaataatt ctaaatctac
    20881 ttcagataat tcagggaaat ctaatcaatc aaccaagaaa acatcaacag ctaaatcagc
    20941 cgttgaatat ctatcaaaaa ctggtaaaaa tgtttacacc tcagcagata aagctttagc
    21001 aaaagctcca aaaggtagtc tagcagggat aacctatgaa gctaaaaacg aagctattaa
    21061 aataggtaaa ggaacggcta aggttgccaa ggctactgct acaggagcat ccaaaactgg
    21121 taaagtagtg aagaaatcta ccatgtcagt caaggactat attgtaaaat acggtaatca
    21181 aaaatcaact gaaaataagt ctgaagacga gtaaaaagaa ggagcattga tttgctcctt
    21241 ctttttactt tgatttctaa ctgaagatgt caaggaaaat ttctatttat gcaaaaaaat
    21301 tattttaaat tgtctataaa tgaattaaat atttactgtt caaagttgta taattaaaaa
    21361 gggcttatgc tggtaaagaa cagaattatt atctaaacaa aaacttgata aaccagcatt
    21421 tttagccaat aaaaaaagtg aaataattta atggaaaatc tcttttaatc atcgaaaatt
    21481 tatgttatta tgataacata aagatgtaaa tatcgagacg tctttttctt agttagatca
    21541 ttgacaagtg aacaaataag atttgtcgat gatataatta acttattaaa aatattaaaa
    21601 aggaggtttt tatatgttcg attctattaa aaatttggtt agcggaatga cgcctgatat
    21661 gaaaacttta gtacaagttg ttttgtattt cttggcattc gttttttcgt tgaaaccagg
    21721 attcactgca atgaaatttt ttggtgatgc aaaatgggga gatggattaa aatatgttgg
    21781 ggcgattatt gcaatcttta ttattcctgt aattacaacc gttatgcttt acacaatggg
    21841 tactaaaaca ggtaatgatt tgaaccaaaa agctaatatc atatcagcac ttattccagt
    21901 tgttggtatc tatctagttt caaaatttcc aaaaaatgaa ctgttaggtt aaaagtgaat
    21961 tgaacaaatt tggataatat gccgatttgt tcaatttact ttttaccaaa aaactacgct
    22021 ccaagcgtag tttagaagtg agggaagaaa gtaaatgtaa gatggttttt gatagagaaa
    22081 aaatgttagc tcacgccaac gaagtattaa tgagcagtct gaaaggtacc gaactggcaa
    22141 agataatgaa tatgaatgtt aaccagttct atgattatcg aaatgggagt aaaaagattg
    22201 aaaaagccag acttgaaacg cttattaaat tcgaaaaagc atatgtatat atgctagata
    22261 aacagaaaag aactattgac tgaaaaaagg agttttacaa taatggcaaa attcaaagat
    22321 attaccgaat ctattaatta tgtggcagaa acagttcctg tagttgcact ctctttgaag
    22381 ccacaattac tcgaagtgta caaaaaagaa gaaaaagaag cgaaggcaaa aaaagctaaa
    22441 gcaaaggtat ggaaagaatt cgatgcgttg ctgaccaaag atttaccaaa gaaaaattat
    22501 atggtaattg aagatgtaca aaagctcaac agtgagggag ttatagatga ggatgatgct
    22561 attctcgatt ctgagaagta tgtcgttcta ttgaagtcaa gtttgaatta tgtagctgat
    22621 ctaccagaaa aatttaaaga gaagctatta gcaggtgtcc gttttatgga tagtagtggt
    22681 caattattag ttattccgga tgatcctaat gtgtttgaat cagaagttga agaagctaca
    22741 gacttctata gcgcagtaga gcaattagaa gtagctacta atggattaga acgaattgct
    22801 gagaccttca actcttctga agaagttgaa tttgaagccg tagcagaaaa tgtaccagat
    22861 gaaaaagaag ctctttttgt ggatgataac aaaccaaccg aagcagaaaa ccaagaagta
    22921 agcatagaag aaacacaaat acaaacagaa acctaccaac aaccaaaaat tgatgaaaaa
    22981 cccgaatccc aaagtgacaa agaaaattat gtttatgaag ctgaaaaaat cacatctgaa
    23041 agtgatgtac cgaaaaactt agatgctgat tttttagaaa aaaattttga acagatcatt
    23101 gctgacaaat ttcaacctgt agttttagat gagattaatg accctgtcga tttaaacgag
    23161 gagatgctat ccatacctga gttgaaacca ttgctgtttt tagctaaaga gagtatgaac
    23221 gctcgcatct ctattgctaa taataaaatc aacagtgaat taaataagac gaaggagcaa
    23281 ttgatcctca aaggaaagca aatgttagct gatgagcttt tgcggataga ggaagcaacc
    23341 tcattaaatg gtcaaaatca gtttacaaat acactatcgg ttgctaaaga gagctacgaa
    23401 gcagaagcat ctaaaattga tgatttagtg atggaaaaat ccaatatcat tcgtaaagat
    23461 tatgatatgg cgaaacaggc ttatttggat gctgaactaa agaaactaga gcaacggtat
    23521 gatgctgagc atttaccaga agttaaacaa caagaagatg aatatagaaa agcaactgaa
    23581 gaaagtcttg atcaacagta ccaagaagca attgaatcta ttaaaaacga tgcattgaaa
    23641 caaagccaag aagcaaaaga agttgtggtg gaacgaatta tcaattcatt gaaaccagaa
    23701 attgaaaaat cattaacaga cgtgcaagaa aaaactttag agattgtcga aaaaacaaag
    23761 tcagaaaatg aagctgagtt ccatgataca aaagagaaaa caacagatgt ggttgtcaaa
    23821 tattttgcga acaaagaaga agttgaaaag caggtagcta acaacacgaa agaattagaa
    23881 acaaaacttg tagagcaaca aaaaactatc gaagaatata aagatcgaat gaaagaggtc
    23941 aaagatttag cagagggtta taaattaaat agcgaaaagt tggcagaaca aagtgaagct
    24001 ttaagagaag acttatctcg ttcccgaagt gatctagctc aaatggcaga aaaaacgaaa
    24061 tcattagcag ttgctacaga aaatcaatca agttcaaaac gtgattttac aagtaaaaag
    24121 atggctacta tcatttctgt cgctgcaatg gcttgcggaa cgatcttggg atcgtcctac
    24181 tttattagtc ataataatca acaagcacag gctcaaactc aaacatctat ttcgagagtg
    24241 gaaaattcga ttgggacaaa tacgaactct gcttcaacaa atagtagcta tgaagcaaca
    24301 ccaactacag agttcaaagt tgggaaagat gttgtcatca gtattgatgg gaaaacaact
    24361 aaggctgaag tgatttctat tgatggagaa aaagcagttg tgaaaactcc agacggaaat
    24421 cagtacaaaa ttcaagctca cttatctgat aataactaag gagggctatt atgcgagaag
    24481 aaaaaatagt ttatccagta attcaaaaca atcaagaaaa catgacctct tctcagcact
    24541 tacaggaagc acagctcgtg tatcaggtaa atgaactacc acaaacgaac gagacaatga
    24601 gcaagtcaat atctttaatt ggcttgctta ttgttgcaat agtgataact gtaggtgttt
    24661 accgtaagtt gaacgtgaaa ggaagtattt ctgatggcag ataactcaaa ctatggattt
    24721 aaacataact tacatcaaaa accttctgaa acaattgtca gagttgaatg gcttgaaaag
    24781 catgtcaata gcacctattc tgttacagca aaaagattaa ttgtatcagc tatagttgtt
    24841 gcagtcgttg ttcttggatc aattgtttac ttagtttctg atacgattaa actgaaattt
    24901 atttttgttc caacgttatt aatgataatt ggatttctta ttctaattag ccagtatatg
    24961 tttattgatc catctagtgg ttcattgatt tctggttcta ttagactgtt caaatcagta
    25021 gttaattcag caagagtatc tatggggaaa aagaaaccat ttcgaggcac agagatttta
    25081 aaagtgaaac aagatggaac aatcgtatat cgagatggga gtgtagcatt aatgttcaat
    25141 ctagatgggg ctacatcact aaccgctttt ccagaagaag ttatggctca ggaatcgaaa
    25201 tcaatacaat atcaaaatac cagagatcgt tccttagctg aaatcaaaat cacttcatct
    25261 caacctcaga atacggaaag acaaactcga aatatgaaaa tacaaaaacg aaatgcaagg
    25321 agtaacaaag cagtctttga cataatagat cagcaagaac gatttgtatc agaatatatt
    25381 gatggtgtga aaacaacagt aatccaatat cttatcttga aatctcaatc taagatggta
    25441 ttggatgaag gtgtggaacg tttagaaaac tatacgagta gaggacttta ttatagtgtc
    25501 actcagttgt cagctaaaca aacaaaagaa atattatctg atatttatgc actgaaatag
    25561 aggtgagaga ttaaatggaa attatgggta gatcacaact attaaatttc aaaaaaaaga
    25621 gaaaaactaa aaaagaacaa aaaactagaa attcaaaggt agtgaataat acctttgtta
    25681 gtgatttaac atctttagtt ggttatcaat ttacaccatc ttacattagg acaggtaagc
    25741 ggtggggaac aattgtgaaa ttagtgaata cttatggaat gaatagaaat tatggatttg
    25801 gttggatggt taaagctatt cctgaagtga gagtagaagg ggtaaaagcc tatctaattg
    25861 aagcagataa gccagtgtca caaaaagatc aacaagaaat aatgcacgag aatgttgggg
    25921 gatcaacgaa tagttatgaa aataatttag aaggaaaaaa ttcagatgct gaaattagca
    25981 aaactgttat gcggattatg gatttgaata cagcatcttt actagacagc atggcaaata
    26041 aaattattga ttggaagcta gaaatcctat tagtatccga ttctcctaat aaaatcagcg
    26101 aacagctaat taaactccaa cggttgtatg atgaaaaaat gtatggatta aagcttatgt
    26161 catatggagg agatcaacgt gatctgtttg atagactttt aagtgaacca atcgggaatg
    26221 tctatgagta tacgtctatg agttcggatt ttgcaggaaa tgatcatgca attcgcaaag
    26281 gtttagatga tgcgaatgga tgggctatcg gcactatgtc tactagctac gcaagtggtg
    26341 tagcttttat ggcactggat gattctttta caagtaaagt tttagtggca tcacacaaaa
    26401 acgctacaat taaaggctat gatgaaaaaa tctcagcatc atcactttgg gggcaattga
    26461 ttgctaataa tgcaatggca aatcataaac gaacttttca tattgtctta aataaatttg
    26521 attactttgg tgatccaact ggtagaacat ttgttgccaa accttcgtta aacagtgtaa
    26581 tagaaaaggt taatttggct gaagaaggtc ttaactcttt ggagcttttt ggtaatcaaa
    26641 aggacattgg tgatttatat agacggaatc tcgataaact aactcagatt ttttatttgt
    26701 tagcaggcag aacattagat tctgcaacta gagttttatt gaaaaaagaa ttaggtaact
    26761 tttatataag tcagaaactt tgggatatta attatgaaga acgttcaaaa cttttggtga
    26821 acagtagtga tacaatgcca gttcttgggg attttattag ctatttgact aatgctgaaa
    26881 caaaagccaa aaaatctggt actgaaaaag aagtcgatcg tattattgta ttaaaagaca
    26941 cattgagaac agcattagac agcttctcta ggatgtttaa tcaaagaacg acactgaaag
    27001 aaatcggtaa aagtgacaaa ttacagtttt actataactt aggtgatcta agagcagaaa
    27061 ccaatgttat ggaagctcaa tttttaaata cctttgattt catcacatca caagcaaaaa
    27121 aagatgatat tgttatgatt cacggcttcg ataagttatc tattgaaacc gttgggctaa
    27181 ttaaaaaaag attaacaatg cttgaagaag atggaattcg tcttgccttt ctatttgata
    27241 caatcggttc aggagaagac aatgaataca aagaagatat tgaaacagct gatatattca
    27301 atacagatgg aaaaatttac caaagttttg aaagtgattt taattacact atcattggaa
    27361 agatgaccag tggagagtta atgaagtatg aaaaaaaagt tgctcctgct agaaaaggag
    27421 aagatgatca aaaactttct gttgatttga gacagtattt gacaacagga agaagtaata
    27481 aatttcagat caggagacca gtggatctga ctaataattt tgttattgga gagtttattc
    27541 tttaagtttt atctttgatt ttgagtgtat aaggaaagga taagaaaaaa catgtatatt
    27601 tgagactaaa aacagtctta gagaacatgg tacgttttgt gaaaagagaa ctatagaaat
    27661 ttcataaagt gaaaccttac tgagtgaaat aattatagtg gaggttaaat aatgaaacca
    27721 aacataaaaa ttttagatcg aatatttcta ggtagagaca cagaagtaat cctaattcaa
    27781 catgaagaag gatttgaagt tagtataggt attcagaaac ttcaaaaacc tcattattgt
    27841 aatcagttgt ataaaaactt tactgatgaa gaaaaagcga gagtt
//
LOCUS       DAIGUC010000039        27495 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.039, whole genome shotgun sequence.
ACCESSION   DAIGUC010000039 DAIGUC010000000
VERSION     DAIGUC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.039"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            299..1960
                     /locus_tag="NOB46_001802"
     CDS             299..1960
                     /locus_tag="NOB46_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1058734.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="NOB46_001803"
     CDS             complement(2030..2377)
                     /locus_tag="NOB46_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HCI1058735.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /locus_tag="NOB46_001804"
     CDS             2461..3402
                     /locus_tag="NOB46_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058736.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="NOB46_001805"
     CDS             3403..4446
                     /locus_tag="NOB46_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058737.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="NOB46_001806"
     CDS             4452..5522
                     /locus_tag="NOB46_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058738.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="NOB46_001807"
     CDS             5512..6465
                     /locus_tag="NOB46_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1058739.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="NOB46_001808"
     CDS             6477..7487
                     /locus_tag="NOB46_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1058740.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="NOB46_001809"
     CDS             complement(7772..8593)
                     /locus_tag="NOB46_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI1058741.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="NOB46_001810"
     CDS             complement(8690..8968)
                     /locus_tag="NOB46_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058742.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="NOB46_001811"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="NOB46_001811"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCI1058743.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="NOB46_001812"
     CDS             complement(11724..12311)
                     /locus_tag="NOB46_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058744.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="NOB46_001813"
     CDS             12486..13808
                     /locus_tag="NOB46_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1058745.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="NOB46_001814"
     CDS             13963..14739
                     /locus_tag="NOB46_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI1058746.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="NOB46_001815"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="NOB46_001815"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCI1058747.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="NOB46_001816"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="NOB46_001816"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCI1058748.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="NOB46_001817"
     CDS             16629..17258
                     /locus_tag="NOB46_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058749.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="NOB46_001818"
     CDS             complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="NOB46_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCI1058750.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18700..19122
                     /gene="mgsA"
                     /locus_tag="NOB46_001819"
     CDS             18700..19122
                     /gene="mgsA"
                     /locus_tag="NOB46_001819"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCI1058751.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19445..19981
                     /locus_tag="NOB46_001820"
     CDS             19445..19981
                     /locus_tag="NOB46_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI1058752.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20021..21784)
                     /locus_tag="NOB46_001821"
     CDS             complement(20021..21784)
                     /locus_tag="NOB46_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058753.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21787..23502)
                     /locus_tag="NOB46_001822"
     CDS             complement(21787..23502)
                     /locus_tag="NOB46_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058754.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24281..24505)
                     /locus_tag="NOB46_001823"
     CDS             complement(24281..24505)
                     /locus_tag="NOB46_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058755.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24696..27473
                     /locus_tag="NOB46_001824"
     CDS             24696..27473
                     /locus_tag="NOB46_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI1058756.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEVKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
BASE COUNT         8961 a         4967 c         5524 g         8043 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgaggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag
    18661 taaataagta tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct
    18721 catgaccgaa aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa
    18781 aaacatgaac tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg
    18841 ccgatccatc ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt
    18901 tcggaggatc agttagattt ggtgattttt cttcgagacc cgctggctgc acagccccat
    18961 gaaccagatg taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg
    19021 aatatcggaa cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga
    19081 agaatcgtcc atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa
    19141 aataacgttt aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg
    19201 atataatacg aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta
    19261 aatgtgaaaa tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa
    19321 aataaagcgt taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt
    19381 cgcggtttta ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct
    19441 aaaaatgaag aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc
    19501 attgatggtc actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt
    19561 cacatttatt ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg
    19621 cgcagtttta gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg
    19681 atttacattg aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga
    19741 gatcacttgg aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt
    19801 tttgacacca ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg
    19861 ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta
    19921 cgtaggacgt agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgctaaata
    19981 aaaaacaagc agtcttccca tcccagaaga ctgcttgttt ttattgtgct gtgaattgtg
    20041 cttgatagag ccgtcggtaa taaccatctt tttgaagcag ctcatcatgg gtgcccattt
    20101 cgacaatagc tccctgatcc atcactaata tctggtccgc atttttgatt gtggacaggc
    20161 gatgggcaat cacaaaactg gtttttcctt ccatcattgc taagaaggct tgttggattt
    20221 ttttctctgt caatgtatcg actgagctgg tagcttcatc taagatcaac atagggggat
    20281 tactgatcat cgttcgagca atcgtcaaca gttggcgttg tccatctgat atctttaacc
    20341 cttgaccgcc aatcttagta tctaattttt ccggcaaacg ttctacaaat tcatacatat
    20401 aagaggcttt tagggcatca ttgatttctg cgtcacttgc ttccggattc ccaaaacgaa
    20461 gattttctcg caatgtactg tcaaatagcc aagtatcttg taacaccatt ccaaaacttt
    20521 tacgtaatgt atcacgttgg atagagcgga tgtcatggtc atcgactgta attgttcctt
    20581 ttgttgtgtc ataaaaacgc atcagcaaat taacaagtgt ggattttccg gcccctgttt
    20641 ttcctactat agcaatggtt tgacctggat aagcagtaaa attgaaatct tcgatcaaac
    20701 gctgcttggg gtcataagaa aaagaaacat gatcaaaaga gacttttcct ttgatatttt
    20761 tgggttccaa ggcataggca tctggcaaat caggcttttc ttctggctga tcgatcaaat
    20821 caaatgctcg ttctagacca gaaaaagcgg tttgcagttg tgtcgtgatt ccagaaagtt
    20881 cgataaatgg tttagaaaac tgacttgagt agatcgtaaa gctggaaatc acaccaacag
    20941 tgattgacga accactcttc aatgccaata ggccgccaac taaaccaatc gataaataag
    21001 caaggtgatc tacaaaacga gaagacgggt ttgtcaagga agaagaaaat tgtgcccgtt
    21061 gtcctttttc atatagatca gcatttagca gttcaaattg ctgttgacta gcttcttctt
    21121 gctgaaaagc tttcacgatt ttctggttac cgattcgttc ggtcacaaag cccgagatat
    21181 ccccaataat cctttgctgt ctatcgaaat ttgtttgtga agcacgagca acgatccaac
    21241 tcacaaggaa aataattggt gtagaacaaa gaacgaccaa tgtcagaagt ggacttagac
    21301 gcatcataaa aataaacgaa agaatgatga ttgccactcc agaaaataat tgattgaagg
    21361 ccgcagaaat tgcaatggaa atattgtcca tatcatttgt aaatcgactg acgatatttc
    21421 cgtgggagtt ttgatcataa taacgaagtg gcaatcgatt cagatgagca aatgcatctt
    21481 ttcttaattt tgcaacggat aagtaagcta accgattgct taacacttgg atgagccatt
    21541 gactgactac gttgattaaa acgataccac cgaatagaat aagtaaatgg aacagtcgat
    21601 tgaagcggac ctgtccttct ccaatcattt gatcgatact ttgaccaatt tgtaacgtca
    21661 tcacaactgt tgcaatccca ttgatgattc ctagtatcac agctagccaa atgtcttttg
    21721 cataggcagt aaggtaagga atgaatcggc ggagcgtctg caaggataat ttttttactt
    21781 tcataactat tcttcctcct gtgatgcgac gatttcctga tattctgctg attgagcaag
    21841 taattcttca tgggtaccct gagcagcaat cttaccttga tccatcacta agatatgatg
    21901 tgcttcttga atagagcgga cacgttggga gataataatc actgtactgc caagataagt
    21961 ctgtagcgcc ttacgcaaat ccaagtctgt ttgataatcc aacgcactta aagagtcatc
    22021 taaaatcagt aatgctggct tggcaatcaa agctcttgca atcgtcagtc gctgtttttg
    22081 tccgccagag aaatttttcc cattttccat gacttttgta tctaaaccat ttggaagctg
    22141 acggacaaat tcttctgcct gagcgatttt cagagcttcc caacattctt tttctgtggc
    22201 gtctttctta ccccattgaa ggttttcacg aatagtcccg gtaaatagta cagaagtttg
    22261 gggaacaaga gcaatttgct gacggagatg atccagctgc caagaacgaa catccattcc
    22321 gtccattata actgtaccgg aactgacatc atagaaacgc ggaatcaatt gtgtcaaagt
    22381 cgttttcccg cttccggttg gaccaatgat tccaaggact gtatttcgct tcagctgaaa
    22441 tgtaatattt tggagagaaa gaccagaatc aggagtataa cggaagtcaa catggtcaaa
    22501 agcgataatt gcttcagaag aaaaatcggg agtagtactg acctcagctt caagaatcga
    22561 attttctgtg tctagcacct ctttcacccg atttcctgaa gcttcggcac gtgtgaagat
    22621 cacgacgagg tttgaaacaa cgatcagtgc caaaagcatt tgattcatat aattgatcaa
    22681 agcaagaact tgtccttgtt gcaagctacc aatatttact ttgatcccgc caactgtcag
    22741 caaacagatg atcccgacat tcatgatcaa ggttgtagca ggtgataata gggcagagat
    22801 attggaaaca cgtaaataat tgttcgctag atcatttgtg cttttatcga acttctctgt
    22861 ttcttttttt gtctgcgcaa atgcgcggat gacacgaaca ccgctaagat tctgactaac
    22921 gtgttcattg agctgatcta gtttttcttg cactttttgg tagagaggaa cggttttttt
    22981 gatgataaaa aataaaatga ttgagaaaat aggcaataat gctaagaaaa acagacctac
    23041 ttcccagtcg atcacaaaag ccatgaccac tgacccgata cttaaaaacg gtgctctgat
    23101 caataaacga atgaccattg ctaaagctag ctgaagctga ttgatgtcgt ttgtcattcg
    23161 ggtgatcaag gtatctgttc caaaatgatt caactcgttg tgagagaaag tattgatttt
    23221 tttgattagc tgattacgta actctgtacc aaatccttgt gaagctactg aagcatagta
    23281 ttggcaaatg atagcacaaa tcagaccaat cacagacata gcgaccatcc ataagcccat
    23341 ttcaatgatt tttcctcggt cattcatttt tagtccatta tcgatcaagg aagccatcat
    23401 taaaggcagg acaagttcga agacagcttc aagaaatttg aagaacgggc ccaaaatgat
    23461 ttgcttacga tagtcttttg cataacgtaa taactgaatc atatgattcc tcctattatt
    23521 tatttgtcca caattgaaaa aacaagtact accacattgt agcttaggaa atttagaatg
    23581 aaaagagaac aagccttttc ataaatgaaa gttttattat gaagaagctt tagaaattga
    23641 atagactatt ttttttaaaa aaaagaaaat gagaaaacat gccagtctct tcattcatag
    23701 gaacgtctat tttacttaat ttttctataa atgaattctg cataaaaaat atatcaagta
    23761 aatgtttata gatgaaactc tatttacttc ttttttaatt tgttcttgca atcttttttg
    23821 ctacgtaatt tttgtaaaaa agtgggttga gagaaatcta attgattttc aaagaaggag
    23881 tatgaaaatg agaaaaatat ttattcgttt attgtgggta ctatcttaga ggaataaata
    23941 atagtggaga aaactatggt ttggcgcaga ttctatcagg tttgatggaa cgaagacaac
    24001 ctcccgacat caagtcaaaa gctacttgag attttgatct gaaaataaaa aaagaaaaca
    24061 aggtaggaac atcaatgttt ctaccttgtt ttcgtaatca atgggaaaaa actaagagtg
    24121 gtgtacgtaa tcaataaaaa ggatggtgac aacagtacct ctttactctc tgaaagcatc
    24181 ataactcgtt tttcctcatt atgccaataa attgttgtta taccacatat aaggatttgt
    24241 aatagctaaa aacagacagg aaagttgaaa tctgtgaatc ttattttgta tggaaggatt
    24301 tatagaacgc aaaaatcaag ataaagatga ataaaaatcc tgtttcggct atatattgcg
    24361 tatctacgcc aataaaacga gtttgttctg tcatagccat ataaagcaaa ggcaaaaata
    24421 caactacagc gagataagat ccgatgattt ctcgaaaagt tttccaggaa gtatgtttcc
    24481 tgtttttata tttatccgat ttcattgaat agtcatagcc tccttattct ttcatatgtt
    24541 gaaattccag tataaaaact ggaaggaact gtacgttttt tagaataaaa attataaggg
    24601 ataagtaggc tgctgtctat aataagatat atttttcaat tctttattaa agattttatt
    24661 gacaaaatga atccgttttc tatgatggag gaggggtgaa taagttgttg aagaaggaaa
    24721 ttttatgtta cttagagaac cagacagcct ttttcgattt agaacatatg aacgaggtct
    24781 ttacagcaca aaggttagct gatcattttg gggtaaaaag aaacacagtc agtcattatt
    24841 tgaaccagtt aaatgatgag caactactag tcaaaatcaa ttctcgacca gtgatttatt
    24901 tccacaaaga agcttttgaa aaacaatttt ttaagttacg cacgaatttt tatttttcta
    24961 tcgatgatct caaagaggaa cagccttttt tcgcgcaacc aaaagactta ttctctttta
    25021 tgatcggata cgacgccagt ttgaaagaaa gtatcgaaca aatcaaaaca gctctttact
    25081 atccagatgg cggattacca cttttgatta caggcgaaag tggcacaggt aaaagttatt
    25141 tagttaattt ggtctatcag tattgtctgc ttcatgatct gctagaagat tctgcaccat
    25201 tcatcacttt taattgtgca caatatgcag ataatcctga acttttgact agcaatttgt
    25261 ttggacatgt taagggagcg tacactggtg cagaagaaaa taaaaaaggg gcttttgaag
    25321 cagcagatgg tgggatcttg tttttagacg aggtacatcg cttaacacca gaaggtcagg
    25381 aaaaactgtt cacctatctt gatcaaggtg tgatttatcg tatgggagaa cctaatttgt
    25441 cacgccggat caaaacacgt ctcttttttg ctacgactga agagattact agtcatttct
    25501 taacaacttt cattcgaaga atacctatcc gaatcgaact acctgcactt aatcagcgta
    25561 gtcgtaatga acggctagaa ctgatttact ctttttttct cgaagaacaa agaaaaatgg
    25621 ggagcccttt gtcagtcagt ggaccagctt tgtcactttt aacaagtcag aaattatccg
    25681 gaaacatagg agagctgaaa aatatcgtca aagtttcagc agcaaaagca tatgctgaac
    25741 agcgtgaaca gcctgaaatc catgtcacga tccatcattt gcaaaaagaa ctacttgcgc
    25801 agcctattac taaaaataca gcacagcaag gaatctatat tacgcaagac cagaccttag
    25861 agcaattaat ggagaagcaa cagcccgaac agcagcgaat cgttaaaagt tttgagcaaa
    25921 tcctaattga tttcaagaaa aataactgtc tgctatattc ttgcgaagta aaattaaagc
    25981 aagaagtgat tcaattattt gattttttgc tgtttgagac cagtagacaa gaaaaacacg
    26041 agctgctggt ttattggaca caatctatcc gagagacctt tcgacaaatg gaaactgcct
    26101 atcaaatcaa attcgatgga aacagtgtct atgccttgag ttactatctc tatcagcgaa
    26161 gcactatcaa atggttaccg gaagaacatg atattatcca actaatcaaa gaattagaac
    26221 aacaagtttc tcagtcttat ccatctagtt atcactatgt ccaacgaatt ctggaattaa
    26281 gtaagatcaa attagatatt gaagacacaa gtatggatcg gattttactg acgatctatc
    26341 taaaaaaagc gaaatggtca aaagaaaaac gactgccaaa agcgatgatt gctgctcacg
    26401 gttatgcaac tgctagcagt atggcaaatg tagtaaatcg tttattacaa gaggatctat
    26461 ttgaatcatt tgatatgcca ctagatgtca caccacagca gattgcttca gaaatccttg
    26521 attattgcga aaacagcgat gtttcaaatg gattgatcat attagtagac atgggatctc
    26581 tgaaagaaat ccatcagttt tttaaaaaac agttatccgt accgcttttg attttgaata
    26641 atgtgacgac acctttagca atcacagtag gggaatgcct gcaaaaaaat gtatcattag
    26701 aagagatagc agaagagact gttcgacaga tccagccaga atggcgactg ctctatccag
    26761 aggaaaacaa acccaaagca ctcattacta cttgcttcac tggaatcggt acggcggtcc
    26821 acttaagtga actgctagaa aaaagcttac ctacggcttg tcagttgaaa atcatcccat
    26881 atgaatatca gcaattaaaa gataagaaaa acagtgaccc attattttcc atatacgaag
    26941 tcgtaggaat gattggcacc acagatcctg atatcaccaa tatcgactat ctttcattag
    27001 aagacctcat ctcgggggaa aagatgtctg tactagctga atggttggac actactatga
    27061 atgcttcaga gaaggaaata ttcaatcagc gcatcattcg taatttttca ttggaaaaag
    27121 tactggattc cgtgactatt ctagatacag agaaggtgat gggagaaatc gatcatttta
    27181 tgagagaatt agaggtgcag ttgaatcgaa gcatcagcaa tcccaaaaaa ttagcgttgt
    27241 atgtccatgt gagctgtctc attgaacgat tgatccgaca aatgccaatc gaaacctatc
    27301 aaggattaga gaaatggaag cagtgtcaaa aagaagggtt atctgctatt aaatctgcgt
    27361 ttagtgtcat tgaagagcat tatagtgtca tgatccccaa ttctgagatt gcctatatct
    27421 atgatatttt gagtgaagat acagagtttc tctcgataga agaagaattt tgaacataag
    27481 caagttgttg ccact
//
LOCUS       DAIGUC010000040        27381 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.040, whole genome shotgun sequence.
ACCESSION   DAIGUC010000040 DAIGUC010000000
VERSION     DAIGUC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.040"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            154..384
                     /locus_tag="NOB46_001825"
     CDS             154..384
                     /locus_tag="NOB46_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HCI1058757.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            481..1782
                     /gene="murA"
                     /locus_tag="NOB46_001826"
     CDS             481..1782
                     /gene="murA"
                     /locus_tag="NOB46_001826"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI1058758.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1795..1971
                     /locus_tag="NOB46_001827"
     CDS             1795..1971
                     /locus_tag="NOB46_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI1058759.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2106..2402
                     /gene="yidD"
                     /locus_tag="NOB46_001828"
     CDS             2106..2402
                     /gene="yidD"
                     /locus_tag="NOB46_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCI1058760.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2586..3053
                     /locus_tag="NOB46_001829"
     CDS             2586..3053
                     /locus_tag="NOB46_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058761.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3138..4022
                     /locus_tag="NOB46_001830"
     CDS             3138..4022
                     /locus_tag="NOB46_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1058762.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4136..4372
                     /locus_tag="NOB46_001831"
     CDS             4136..4372
                     /locus_tag="NOB46_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HCI1058763.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4460..4540
                     /locus_tag="NOB46_001832"
     tRNA            4460..4540
                     /locus_tag="NOB46_001832"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4494..4496,aa:Tyr,seq:gta)
     gene            4547..4618
                     /locus_tag="NOB46_001833"
     tRNA            4547..4618
                     /locus_tag="NOB46_001833"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4579..4581,aa:Gln,seq:ttg)
     gene            4743..4913
                     /locus_tag="NOB46_001834"
     CDS             4743..4913
                     /locus_tag="NOB46_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058764.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5133..5840
                     /locus_tag="NOB46_001835"
     CDS             5133..5840
                     /locus_tag="NOB46_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1058765.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5900..6544)
                     /locus_tag="NOB46_001836"
     CDS             complement(5900..6544)
                     /locus_tag="NOB46_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCI1058766.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6671..6958
                     /locus_tag="NOB46_001837"
     CDS             6671..6958
                     /locus_tag="NOB46_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058767.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7066..7386
                     /locus_tag="NOB46_001838"
     CDS             7066..7386
                     /locus_tag="NOB46_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1058768.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7467..8780
                     /locus_tag="NOB46_001839"
     CDS             7467..8780
                     /locus_tag="NOB46_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI1058769.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8777..9496
                     /locus_tag="NOB46_001840"
     CDS             8777..9496
                     /locus_tag="NOB46_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCI1058770.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9624..10175
                     /gene="raiA"
                     /locus_tag="NOB46_001841"
     CDS             9624..10175
                     /gene="raiA"
                     /locus_tag="NOB46_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCI1058771.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10397..12931
                     /gene="secA"
                     /locus_tag="NOB46_001842"
     CDS             10397..12931
                     /gene="secA"
                     /locus_tag="NOB46_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCI1058772.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            13058..14159
                     /gene="prfB"
                     /locus_tag="NOB46_001843"
     CDS             join(13058..13129,13131..14159)
                     /gene="prfB"
                     /locus_tag="NOB46_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCI1058773.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14264..14950
                     /gene="ftsE"
                     /locus_tag="NOB46_001844"
     CDS             14264..14950
                     /gene="ftsE"
                     /locus_tag="NOB46_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCI1058774.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14934..15827
                     /locus_tag="NOB46_001845"
     CDS             14934..15827
                     /locus_tag="NOB46_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058775.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15979..17427
                     /gene="cls"
                     /locus_tag="NOB46_001846"
     CDS             15979..17427
                     /gene="cls"
                     /locus_tag="NOB46_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI1058776.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            17764..18621
                     /locus_tag="NOB46_001847"
     CDS             17764..18621
                     /locus_tag="NOB46_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCI1058777.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18736..19656
                     /gene="pstC"
                     /locus_tag="NOB46_001848"
     CDS             18736..19656
                     /gene="pstC"
                     /locus_tag="NOB46_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCI1058778.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19656..20540
                     /gene="pstA"
                     /locus_tag="NOB46_001849"
     CDS             19656..20540
                     /gene="pstA"
                     /locus_tag="NOB46_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCI1058779.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20555..21361
                     /gene="pstB"
                     /locus_tag="NOB46_001850"
     CDS             20555..21361
                     /gene="pstB"
                     /locus_tag="NOB46_001850"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI1058780.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21377..22135
                     /locus_tag="NOB46_001851"
     CDS             21377..22135
                     /locus_tag="NOB46_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI1058781.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22148..22825
                     /gene="phoU"
                     /locus_tag="NOB46_001852"
     CDS             22148..22825
                     /gene="phoU"
                     /locus_tag="NOB46_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCI1058782.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23047..24081
                     /locus_tag="NOB46_001853"
     CDS             23047..24081
                     /locus_tag="NOB46_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI1058783.1"
                     /translation="MQKKISIIITLFFICILASWFIQRQAALYDVPVIEIERVRIEED
                     QQLITGRLMNTDQKGEVISLTAPYQKNQIETANITTRQIYLVQMHGDEWQLVAKKNDG
                     WLFFFTSVFIGTMLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAILFV
                     VIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTR
                     PYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVIGS
                     MANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIAVL
                     FFLAVRRLKK"
     gene            24078..24845
                     /locus_tag="NOB46_001854"
     CDS             24078..24845
                     /locus_tag="NOB46_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI1058784.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            24945..26513
                     /gene="liaX"
                     /locus_tag="NOB46_001855"
     CDS             24945..26513
                     /gene="liaX"
                     /locus_tag="NOB46_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HCI1058785.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26689..26997
                     /locus_tag="NOB46_001856"
     CDS             26689..26997
                     /locus_tag="NOB46_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HCI1058786.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            26997..27347
                     /locus_tag="NOB46_001857"
     CDS             26997..27347
                     /locus_tag="NOB46_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCI1058787.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
BASE COUNT         9041 a         4669 c         5937 g         7734 t
ORIGIN      
        1 cagtcccttt ttttgcatat ttttagcatt tatttcctaa aaaatgtaag gggattccta
       61 tatttttaag tatacttgtt tttcctttta tacattttat ggtattatca ttttattagt
      121 tattataaaa caatcgttag aaaggacgtc attatgcaag tatacggaat tgatgcggtg
      181 cttcgaatcg tgagtcattt ggcgtttatc tacttagcct tctggtcttt acgttcgtta
      241 cgcattgaaa cttttttcag accaatgcat aatacgcaaa ttagaatggc aatcgtactt
      301 ttttcaattt ttttagggta cactgcaagt aattttttct tagaagttat cgctttatgc
      361 cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta ctattttaaa agcaaggatg
      421 ttataataga aaagattttg agtaagtgta tgctcattgg aattttttgg agggaacaac
      481 atggaagaga tcatcgtaag aggtggcaat caattaaatg gaacagtaag aattgaagga
      541 gctaaaaatg ctgttttgcc tattttagct gctagtttgt tagcagaaga aggtattacg
      601 acattagaca acgttccgat tctttctgat gtcttcacta tgaatcaagt gattcgtcac
      661 ttaaacgtag atgtagattt tgatgaacaa aagaatcaag taacaatcga tgcttcaaga
      721 caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa tgcgtgcttc aatcgttgtg
      781 atgggtccgc tacttgccag aaatggacat gcaaaagtag ctatgcctgg tggatgtgcg
      841 attggtaaac gaccaatcga tttgcattta aaaggatttc aagctttagg agcaaaaatt
      901 attcaaaaaa acggctatat cgaagcaatt gcggatgaat tgatcggtaa cacgatttat
      961 ttagatttcc ctagtgtagg tgctactcaa aatatcatga tggctgccgt aaaagcaaaa
     1021 ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa tcgttgattt agcaaacatt
     1081 ttgaataaaa tgggcgctca agtctatgga gctggtactg aaacaatgcg tattgaaggc
     1141 gtggatcatt tacatgcagt caaccactca atcgtacaag atcgtatcga agcaggtacc
     1201 tttatggttg ctgctgcaat gacacaaggc aatgtgctga ttgcagatgc tatctctgaa
     1261 cataaccgcc cattgatttc taaattgatc gaaatgggtg cagaaatcat tgaagaagaa
     1321 ggcggagtcc gtgtcatcgg accaaaacat atcttaccta cagatgtaaa aacgatgcct
     1381 catcctggtt tccctacaga tatgcaagct caaatgacag ctatccaatt agttgcagaa
     1441 ggtacaagtg tagtgactga aacagtgttt gaaaatcgtt tccaacattt agaagagatg
     1501 cgccgtatga acgctcatgt caaaatcgac ggaaatgtag caatcatgga tggaaaccat
     1561 gaattgcaag gtgcagaagt atatgcaaca gacttgcggg cagcagcagc attagtttta
     1621 gctggcttga aagcaaatgg aatcacacgt gtgcgtaact tgaattatct agaccgtgga
     1681 tattataatt tccatatcaa actacagcaa ttaggtgcag acgttgaacg tgtagacatg
     1741 gatcaaactt ctgctgaaaa aacagcacaa acgattgctt aaggaagtgg ctgaatgagt
     1801 aaccaacgat atatcttatt aactttgata aagattttag tggtgatctt attgcttatc
     1861 cttctttttg tggccggaac gatgatcgga tatggtgtca tcggtggcgg caatccattt
     1921 aaagtattcc agccaagttt gtggattcat attcgagact tttttcattg ataaataaga
     1981 atcacagtgg ttctagtcga tatgaagtga gccatgaagc agaacatgac aaaagaaaac
     2041 agaagggaac gttgacgtta gtcgcgatcc ctttttttag taaaagaaaa gaaggaatct
     2101 aattgatgaa gaagatattg atttatttag ttagaggata tcagcgcttt atttcgcctg
     2161 catttccacc tagctgccgt tattacccaa cctgttccaa ttatatgata aaagcaattc
     2221 aaacccatgg tgcactaaaa gggacggtaa tggggactgc acggatctta cgctgtcatc
     2281 cttttgtcaa aggcggtatc gattatgtac cattgacatt ccaattaacg cgaaataaga
     2341 aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa tacgagtagc actgagcgat
     2401 aaagaaacaa tttggaaaat agcttcttat attttgcaaa attgtgagtt attgccgaag
     2461 tgttggattt tgaacaccgt caaaaaaagg ttgtgaaaaa tacgggtagc actgagcgat
     2521 aaagaaaaag aggaaaatta ttgtcaaagt aacaactccg caactactta tatgggggac
     2581 aaaaaatgat cgaagaacta aacaagaaag atttaccatg gtccttgtta ttagatgcag
     2641 atcctgataa agaaaaagtt caagtatatg tttccagagg gagtggctgg atatggaaag
     2701 aaaaagaaaa aacaataggt gtactgatct atgtggcaag ggaaaaagaa tacgaaatcg
     2761 tcaatgtagc agtagcccca acgtatcaag gaaaggggat tggcggaaaa ttacttgaga
     2821 cagcttttca gaagctttca caactcgctt ccagtcaaac tcagatcatc atacgaaccg
     2881 gcagtactag cagtgcggcg ttacatctct atcaaaaaat gggctatgtg gagattggtc
     2941 gagtcaaaga ctattttatc catcattact ctgagcccat ttttgaaaat ggagatcaat
     3001 taagggatca agtaatttta gcaattcact tacctaaaaa tagctttaac taataaactt
     3061 tcaattcgag aaaatgcttt caaatgctaa atagatacat tacaatagct ttagcaaaca
     3121 aaaaggagaa tatttttatg ggaatattag tttttgattt tggtggatcg gctgtcaaat
     3181 atggttgttg ggatggcaaa gagattaaag gtaagggaca atttgcaacg cctgaatctt
     3241 gggaagaaat gaaagcgcaa ttatttcaag tttataaaaa aatactcgtt tcttttgaag
     3301 tcgaaggaat tggaatcagc tctcctggag tagtgaataa tgagaaacag gtgattgagg
     3361 gaatcagtgc gattccttat attcatggat ttaatatttt ccgagatttg gaaactctgt
     3421 ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc cggaatggct gaattttatg
     3481 aaggtgctgc ccgtgattat caagatgttg cttttgttgt ggcaggaact gggattggcg
     3541 gggcgttgtt cacgaaagga caaatcaata aaggggcaca tctttatggt ggagaatttg
     3601 ggttgatgtt cttaaatggc gataagacat tcagtaaact tggtacagcg gtacagatgg
     3661 cttggcgtta ttgtgaacgc aaaggtctcg ataaaaattc ttataccgga aaagatgtct
     3721 ttgaattagc agaaactgga gatgcaatag caaaagaaga agttgagagt ttttatacgt
     3781 atcttacaaa gggattattc agtattcaat tttcgtttga tccagaagtg atcgtattag
     3841 gcggcggtgt ttctgcaaaa gaagggctca ttgatgagat caaaagccga atgaagaagc
     3901 tgacagaaca attcgatctg catgatttcg aaccgcagat tttattatgt gaatacagaa
     3961 acgatgctaa tcttgtaggt gcagcagcaa actatctcgc tgtacgtcaa ggggagaatt
     4021 aagagcttta gagaaggtgc agcttgcata aaagaagtga atgaaatgaa taggagattt
     4081 ttacctaagg aatgttttat ttgctgcagt atgataaaat atctgagagg tgaaaatgat
     4141 gtcaaaaaaa aataaagatg ttgaagtgcg tatagaagaa gtgaaaaaag atatcaaagg
     4201 taagaattat gaagtcactc agttatttat agggaaaaaa atgattggtg agatcttagc
     4261 ctatgggcca aaagaatatg aaattttctt tggtgaagaa gattttggaa aagaaaaaag
     4321 tcttgaaaat gcgatagaaa cagtgattcg acactggaat ctgcacgaat aaaaaaatat
     4381 caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa ttaggtatta taactaagtc
     4441 aggttgatac aaacctttcg gaggagtagc gaagtggcta aacgcgacgg actgtaaatc
     4501 cgttccttag ggttcagtgg ttcgaatcca ctctcctcca tttcattggg gtatagccaa
     4561 gcggtaaggc aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagta
     4621 taccacaatc gtaagctctc gttagttcga gagctctttt ttttgctttg ctaccttgtt
     4681 ccttgaagat tctgctgatt taagatagag ttaagttaac tacaagaatt ggagggatcc
     4741 acatgaaatg gaaagaaaaa gtagacgaag cagctgaaaa gttatatgat ttggtcaaat
     4801 cagaaaaata caatattgaa gtgaatattc cgaaaaaagg cggaaaagcg gtccaggtaa
     4861 aatcaaaacg cccaacgaat catacaaaaa aatggatggc taaaaaccgc taataataac
     4921 aaaagatcca taagtcggca ttttcatcga ttttagggtc ttttgttatt ttctaggttg
     4981 aacatatcta aaaaattgtt tctgacaata ggagtaggaa gaacgatgtg tgtctaaatc
     5041 ctctgttgat ggatagaaac ctttatcttt ttcagttgtg aatcaggtat ataccagtta
     5101 taatagaaga aacgaaagga cgggtgtacg ttatgtcgaa tcaattacct gtatatatac
     5161 agattcatga ccaattaaaa aatgaaatcg aacaaggtat atggaaagtc ggagaccgtc
     5221 ttccttcaga aagagaatta gcagtgaaat tcaatgtcag ccgtatgacg ttgagacaag
     5281 caattcaaaa cttggcagat gaaggaatct tagaaagaaa gatcggttcg ggtacatatg
     5341 ttgcgcgaga aaaagtacaa gaaaaaatgt ctggtgcaac aagttttaca gaaattatgg
     5401 aatcgcaaaa tcgagtaccg tctagtcgga caatctctta tttcttgact tcgccaagct
     5461 caagtgaaat ggaaaaacta aacttgagta aagatgacac gatcttgcga atggaacgta
     5521 ttcgtttcgc agatgatgtc cctatttgtt ttgaagttgc cagtgtgcca caaaagctga
     5581 tcgatggcta cagcaaagca gagattactg aatcgttgta tcgcacgcta gaagaaaaag
     5641 gcgggaaaaa gatcggtcca gcgaatcaaa cgattactgc tgtgttggct tctgagaaaa
     5701 ttgctgacta tttagaggta aaacgaggag atgcagttct tcgtttgcgc cagatttctt
     5761 attttgaaga cggtacgccg tttgagtatg tgcgtacgca atacgtagga aatcgttttg
     5821 agttttattt ggaaaaataa aaaacaggtg atccctgatt ccttacttag aaataaaaga
     5881 gaatcagaat cacctgtttt tatatatgat cagttaccag ttgctcgtga taagaaacag
     5941 gaccctcttc aaattggact tgtccgttca gcagctcaat gatggattct ttaaagtggt
     6001 cagcactttt ttcatctaca gcacagatga cgctaacttg atcagtatat tggatttctt
     6061 ttataaaaaa atgttggagt tcaagataat tctgtaattt tcctagttgc ggatacgtga
     6121 tcatcacaga gatctcctgt tgcaaggtac cttctacgat tccaatgtca gacaatgctt
     6181 gagagacagc atgagtgtat gctcgtatta atccgcctgt gccgagtttc gttcctccaa
     6241 aatatcgagt gactactgca gctacattga tcagttgatt ttttttgagg acttccaaca
     6301 tcggtacgcc agccgttcca cttggttctc catcatcgct gcttcgctgg atttcatttt
     6361 tttctccaat gatgaaggcg ctgcagttat ggttcgcttt ccaatgttct ttttttattt
     6421 cttgaatgaa actttttgct tggtcctctg attctattcg tctaagagaa cagataaagc
     6481 gtgatttttt gatctcaatc tcactttgtc cattttcttt tattgtacga tagcgctcga
     6541 tcatcttgtc acctcttttt ttcattttct ttattcagta taaataaagt tctaggttgt
     6601 ttcaacactg taacggttgc gcaatcgctg tagtatgcga taataaagac aaaggtaggt
     6661 ggatctgggg atgcaggaac gaatgaaaaa gtacgatgca attacgcatt atttgaagaa
     6721 caatggcggc tctcaagtaa cgttgacctt tacccaattt gacgaactgc tgtttcccag
     6781 taacggactt cccaaaacag caagggaaag tacagattgg tgggcaaatg attataaaca
     6841 ccctgaaaaa ggtgcctatg gctggataaa tgcaggctat gaagtagttg tcatcaattt
     6901 ggacaaagaa tatgtcgtgt tcaataaatt agtgaaatct agttggctat ttgattaaat
     6961 aaaccgcgtt tagaaaacgt tgacaaattt ctttcttttt atataataga gtaacagacg
     7021 cgaagaaaac gtttgcgtag tttgttttaa aaaggagaga aaagtatggc taaaaaaaca
     7081 atcatgcttg tatgttcggc tggtatgagc acaagtttac tagtaacaaa aatgcaaaaa
     7141 gctgctgaag caaaaggaat cgactcggat attttcgctg tgtccgcttc tgacgcagat
     7201 aacaatcttg caaataaaga tgtagatgta ctgttattag gacctcaagt tcgctttatg
     7261 aaagctgatt ttgaaaaacg tctggaacca aaaggcattc ctttagacgt catcaatatg
     7321 gctgattatg gtatgatgaa tggcgaaaaa gtgttagatc aagcaatcac gctcataggt
     7381 gaataaatag aacagtataa ctatcgaaca agcgatccaa aaaatagatc gcttgttttt
     7441 tcgtatattt ttttagggcg aataatatga atcatttttg gggtagaagg cttctgacga
     7501 gagatattaa agcaatagac tgtgaggagg taaatttacc aaattatgag aagatcgcag
     7561 cagtggaacg tttgggcaac tggattcttt gtcatcgctg tggaatgagg acgtccgtca
     7621 ttgatggaca gcttgcagat tacggttatt tttgtacaca ttgtctatat ttagggcgat
     7681 gcgacactca acaagattta tatttgtttg atcagcctga agcaaaacct cgagaagtcg
     7741 tctttttttg gacaggacag cttactgaaa aacaaacgga aatcgcaaag agaatacttt
     7801 gccattcaga aaaaagacat catcttattt gggctgtaac aggtgcaggg aaaacagaga
     7861 tgctttatcc tattttagtg gaaactttaa aagctggagg aagagtagcg atttgtacac
     7921 cgcgagtcga tgtttgtaat gaattgtttt tacgctatcg ttatgttttt ccagaagaaa
     7981 aaatcacgtt gctccatggg aatacagcaa cggcttatac ctttacttct tttgttatct
     8041 gtacgattca tcagctatac cgtttttatc ggtcctttga tttaatagtg atcgatgaga
     8101 tcgatgcgtt tccttataac ggggatgcag gattagctca tgctgtgcaa acagcgatta
     8161 aaccagacgg acgattcatc tacttaagtg ccacacctga taaaaagtta ctaaaggaaa
     8221 tcaagcagac gtttgacatc cacaaacttg ctttgcgctt tcatcggcgt ttacttcctg
     8281 aacccgtctt ggttttcatg aataattggc gacaaaaatg caagaacaag aagaagataa
     8341 aatctttggt gcggatcatt catcaattaa ttaaagaaaa ccatatcctt ttattttgtc
     8401 caagtatcac gatgatgcat cgtttgaaag ccacacttca agaggctctt ccgagatatg
     8461 agatcacaga tgtttcttca agagacaatc agcgggcgga aaaagtccag aaaatgcgag
     8521 aagcaaaata tgacatactg ttaaccacga tgatccttga acgtggagtc acatttgaaa
     8581 gaatatccgt tatcgtttta ggagcggatc atccggtttt tactaaatct tctttggtac
     8641 aaatcgcagg aagagccgat cgtaaagggc cttatacgaa cagtcaagta tactttttct
     8701 atgaagaaaa aactgcagct attcgaaaag cttgtcagga aatcaaagaa atgaatgaag
     8761 aagggaagaa gatgctgtga ggtgcagttg ctgcagtaaa gatatcgtcc aaaatttaac
     8821 attcagcgag attattggtg tttcgaaata cagattacct cagacttgtt cagtttgtcg
     8881 cgcacaattt catttattgg aaacaagagg ctgttctggc tgtcaaaaac caatccattt
     8941 caatctagag agtacgaaaa agaaagtaaa gtctattccc gtttactgca gtgactgtca
     9001 agaatggaag aagaaatatc cgacctatga ttttcagcac cgtgcctttt ttgtgtacga
     9061 tgaaaatatg aaggcctggc tcaatcaata caagtttatg ggagatatcc gactagcagg
     9121 cacctttgca tataaatgga cgcagataaa aaaagaatac ccgacataca tctattgtcc
     9181 aataccttta tctgaaaaaa ggcgaacaga aagaggattc aatcaagtaa gcgagatgtt
     9241 gaaagcagca agaattcctt ttcagatgct actcaaaaga gagaagcatc tgctggctca
     9301 agcaaaaaac acgcgaaagg aaagattgga gatgcctcaa ccttttgaac ttgcagtcac
     9361 cttttctaag atacaaaata aaaaaatatt gattattgat gatgtctata caacaggaca
     9421 gactcttttc cacgcagcag attgtttgca ggtcgcacag ccgaaaatca tccgaaccat
     9481 ttctttagca agatgaatta gatgtggaaa tttgatagcg atttaatttg caaataacct
     9541 agagttcgat ataatagaat taagaagagg gaaagagtgg tccttctcct tcttgattgt
     9601 ggtagacgaa aggggtaatt tttatgttta gatataatgt acgcggcgaa aatatcgaag
     9661 taactgaagc gattcgcgac tacgttgaga aaaaagtagg caaactagaa cgctatttca
     9721 gtgacgcacc cgatgcaacg gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa
     9781 aagtggaagt aacgatccca ttaccttatc ttgtattacg tgccgaagaa acttctccag
     9841 atttatacgc aagtatcgat ttggttgttg acaaattgga acgccaaatc cgcaaattca
     9901 aaacaaaaat taatcgtaaa tcccgtgaaa cgggcatgaa tactgcagat gctactgctt
     9961 tattcaatga agaggacgaa aacgaaaatg attctgaatt agatatcgta cgtacgaaac
    10021 gcctttcatt gaaaccaatg gatagtgaag aagcagtctt acaaatgaac atgctgggac
    10081 ataacttctt tatttttgaa gatgcagaaa caaatggtac aagtatcgtt taccgccgta
    10141 aagatggaaa atacggactg attgaaacag actgatcagc cttacttaaa taacaacgaa
    10201 aacttgcagc agctactgac agctgccgca agtttttttg agtttcctcc tcttttagat
    10261 gaaatatgaa taaattatga agttcttact ttaatacgct taagatattt caattatcta
    10321 taactaatga taaaatgaaa agtaaagtct acatagtctg gataatacac agaaggaaaa
    10381 ggagattaca caacgcatgg ccaatttgat tcgttcactt atcgaaaacg ataagaaaga
    10441 actaaaacgt ttagatagca ttgcaaaaaa agttgaagca tacgctgacc aaatggcagc
    10501 attaactgat gaacaattac aggcaaaaac tgctgaattc aagggcagat accaaaaagg
    10561 agaaacatta gatcaattac ttccggaagc ttttgcagtc gtccgagaag cagcaaaacg
    10621 tgtattgggg ttatatccat accacgtaca attaatgggt gggatcgtgc ttcacgatgg
    10681 gaatatccct gaaatgcgta ctggtgaagg taaaaccttg actgcaacga tgccggtgta
    10741 tctgaatgcg ttgactggcg aaggggtcca cgtagttacc gtcaatgaat atttagcaac
    10801 ccgtgactcg acggaaatgg gcgagcttta taatttctta ggattgacag ttgggttgaa
    10861 tatcaactca aaatcttcgg atgaaaaacg cgaggcttat aattgcgata tcacttatag
    10921 cacgaataat gaattaggat ttgactattt gagagacaac atggtcgttt accgtcatca
    10981 aatggtacaa cgtccgctga attatgccat tgtcgatgaa gttgactcga tcttgattga
    11041 tgaagcgaga acgccgctga tcatttcagg gcaagcagaa aaatcaacag ctttatatac
    11101 aagagcagac aacttcgtga aacgtttgaa agaagaagaa gattataaaa tcgatataca
    11161 atcaaaaaca atcagtttaa ctgaagcagg gatcgaaaaa gctgaagaaa cattcggttt
    11221 ggacaactta tatgacattg aaaatactgc attgacccat cacttggatc aagcattgag
    11281 agccaactac atcatgcttt tagacatcga ttatgttgtt caagatggaa aagtattgat
    11341 tgttgaccaa tttacgggtc ggatcatgga tggacgccgt tattcagatg gtcttcatca
    11401 agcgatcgaa gctaaagaag gcgtagagat cgaagacgaa acgaaaacga tggcgacgat
    11461 cactttccag aactatttcc gtatgtacaa gaaacttgcg gggatgactg gtacagctaa
    11521 gacagaagaa gaagagttca gagagattta taatattcaa gtataccaga ttccgacaaa
    11581 ccgtccggtc atccgtgacg atcgaccaga tttgctttac ccaacattac aaagcaagtt
    11641 ccatgctgtc gtacaagata tcaaagatcg ctaccgcaaa ggacagcctg tcttagtcgg
    11701 aactgttgca gttgaaacat ctgagttatt atcagatatg ctgaatcaag aacgtattcc
    11761 tcatgaagta ctgaatgcga aaaatcactt taaagaagca gaaatcatca tgaatgcggg
    11821 tcaaaaaggt gcagtgacga ttgctaccaa catggctggt cggggaacag atatcaagct
    11881 agggcttggc gtaagagaac ttggtggcct agcagttatc gggacagaac gacatgaatc
    11941 tcgtcgtatc gataaccagc ttcgaggacg tgcaggacgt caaggagacc ctggtatgtc
    12001 acaattctac ttgtctttag aagatgattt gatgaaacga ttcggttcag aacgaatcaa
    12061 agctttctta gatcgaatga agatcggtga cgaagatgct gtgatccaaa gcaagatgct
    12121 gacgaaacaa gtagaagctg cacaaaaacg cgtagaagga aacaactacg acacacgtaa
    12181 gaacgtcttg caatacgatg acgtgatgcg tgagcaacgt gaagtaatct ataaacagcg
    12241 tcaagaagtg atcatggaag aaaaaagctt atctaaacca ctgatgaata tggtcaaacg
    12301 gacaatcagt cgtgtggtag atgcgcatac gcaattagaa aaagaaaatt ggaatttgga
    12361 aagtatcgtc gattttgctg gcagcacgct tgtccatgaa gacagtattt cccttacaga
    12421 tatcgaagga aaaacctctc aagaaatcaa agaatatcta aacgaacgag cacaagaagt
    12481 attcaatacc aaagcagctc aattgaacgg accagagcaa ctgcttgaat ttgaaaaagt
    12541 cgtgatctta cgtgtcgtgg actctaaatg gacagatcat attgatgcaa tggaccaatt
    12601 acgtcagtca atcggcttgc gtgcctatgg tcaaaacaat ccattagtcg aataccaaac
    12661 agaaggttat aagatgttcg aagatatggt aggtgccatt gaatatgaag tcactcgtat
    12721 cttcatgaaa gctgagatcc gtcaaaacgt acaacgtgag caagtttctc aaggaacagc
    12781 ttctcactca gaagatggag atgccaaaga aaacagtaat actagcgcga aaaaacaacc
    12841 aatccatgtg aacaaggttg gtagaaatga tccttgtcct tgtggaagcg ggaaaaaata
    12901 taagaactgt cacggaaaag atgcaaacta atttctgaca gcaggattgg tgagacaaat
    12961 tcttttttaa agaatttgtc tcaccttctt tctgttattt gacgattctg ttagactaga
    13021 tataataaaa aaagtatagt gaaagaagga aaaaaacatg gaaatatccg aaattcgaaa
    13081 tctcctgaca gaaatgcagg aaaaggtcac aagcttcagg aggtctcttt gacttagacc
    13141 agctggaaga agacattgcg gaagcagaag caaaaatggc tgaacctggt ttttgggatg
    13201 atagcgaagc tgctcaaaaa gtgatcagtg aaaacaatgc aaataaagaa acttatgatc
    13261 aattccattc tcttgctgaa gaactggaag aaatcgaatt gatggtggag atgttgcagg
    13321 aagaacctga tgcagtaatg caagaagaag cagaagcacg tatcaatgcg ctagatgaaa
    13381 aaatgaatac gtatgaatta tctatgttgt tagatggtcc ttatgatcga aacaacgcca
    13441 tcgtcgaatt gcatccaggg gctggcggaa cggagtccca agactggggc agcatgcttt
    13501 tacgcatgta tacacgctgg gcagagcagc atgggtatca agtagagaca ctagattatc
    13561 aagcaggcga tgaagcagga atcaagagtg tgaccctact gatcaaagga cacaacgcat
    13621 ttggctatct gaaatcagaa aaaggtgttc atcgccttgt acgtatctcg ccttttgact
    13681 cagcaaaacg tcgtcatact tctttttgtt cggtagatgt gatgccagag cttgatgaaa
    13741 cgatcgatat agaaatcaat ccagatgatt tgaagatcga cacatatcgg gcgagtggtg
    13801 caggtggtca gcacatcaat aagacagaat ccgctgtacg aatcactcac ttgcctacag
    13861 gaacagtagt agcgagtcag gcacaacgtt cacaattgaa aaaccgggaa caagcgatgg
    13921 ggatgctgaa agctaagctt taccaattag aagtggaaaa gaaagaacaa gaagcagctg
    13981 cactgagagg agaacaaaaa gaaatcggct ggggatcaca gatccgttct tatgttttcc
    14041 atccatattc tatggtaaaa gaccatcgga caaacgtaga gacaggaaat gtccaagctg
    14101 ttatggacgg agatcttgat ttatttattg acggctattt gaaaatgcat ctgcaataag
    14161 agccctttgt taaattgaaa taaaattgta agattttgca agcaagttga aacattgcca
    14221 tgctataata gctaaagact gaaaaagata tggagagaac gccatgattg aaatgaagga
    14281 tgtaatgaag aagtactcaa acggtaccac tgctatccgc aatctctcga ttgtcatcga
    14341 acaaggagag tttgtgtatg ttgttggtcc gtctggagct ggtaaatcta cattcatcaa
    14401 attgatgtat cgagaagaaa aagcttcaaa aggaactttg aacgtcgcag gtcatgatct
    14461 aatagccatc aaaaaccgcg aagttcctta tctacgcaga gaaatcggcg tggtgttcca
    14521 agactataaa ttattaccaa gaaaaacagt atatgaaaat gttgcgtacg ccatgcaagt
    14581 tatcggcaga aaacctcggg atatcaaaaa acgagtaatg gaagtgctgg atcttgttgg
    14641 tttgaaacac aaagtccgag tctttcctag cgaattatct ggtggggaac aacaacgtgt
    14701 ttctattgcc cgagcaatcg taaatacacc taaagtactt atcgcggatg aaccgacagg
    14761 gaatctagat ccggaaaact catgggaaat catgaaacta ttagatcgga tcaatgcaca
    14821 aggaacaact gtcgtgatgg ctacacataa cagtacgatc gtaaatacga ttcgacaccg
    14881 agtaattgct atcgaaaacg gccgcattat tcgagaccaa gcggaagggg aatatggata
    14941 cgatgattag aacctttttc cgccatttat tagaaagtat caagagtttg aaacgtaacg
    15001 gctggatgac agtagcttcg gtcagtgcgg taacgatcac gttgacttta gttggtgtgt
    15061 tcatggcggt catcatgaac gcaaccaaac tagcacaaga tatagaagga aacgtggatg
    15121 tatctgtgtt cgtagacatt ggtacaaaag acgaagagat gaaaaaatta gaaaaagaat
    15181 taaatgactt agatcatgtc aaaaaagtcg aattttcaag caaagaacag gaattgaaga
    15241 aaatccaaaa cgaaatgggc gattcttgga aattgtttga aggggataat aacccgttat
    15301 atgatgtata cgtagtaagt gctaccgatc cttcttatac aaaacaagta gcagaaaaag
    15361 cggcagattt gaagaatgtt tcccgttctg attacggtgg ggcttcctca gatcggattt
    15421 tccaaattgc tggtgcagtt cgaacatggg gattagttgc ggcggcattg ctgctgtttg
    15481 tagcaatgtt tctcatttct aacacgattc ggatcacgat tttatctaga cagcgtgaaa
    15541 ttcaaatcat gcgtttagta ggggcaaaaa atggatatat ccgctggcca tttttccttg
    15601 aaggtggttg gatcggctta atcggtgcca ttcttccgat actgatcatt acatttggtt
    15661 acgcatggtt ttaccaattg atcaatccgt cattattacg atctcattat tcattgatcc
    15721 atccagaaaa tatcgtttgg aaaatcaatc ttttgatggt cggtattggt gtgatcattg
    15781 gttcactcgg ctcgatcatc tctatgagac gtttcttgaa attctagtgt cacaagataa
    15841 atataatcag aaagttggac gatttcgttc cagctttctt tttttatcag ctaggtggag
    15901 taaatggggc ggcttttttc tctttacttt aaaaaacaac ttgggtattc ttaagttggt
    15961 agaaaaagag gtgaagccgt gaagattatc gttgacaatt tttttacgat ccttttgatt
    16021 atgaatattt tgctttcctt tattatcgtt tttcgagaaa gaaaggaaac tgcgcaaaca
    16081 tgggcatggc tgctcgtttt gatgttcatt ccagttgtag gatttatttt atatattttt
    16141 ttaggaagag ggatttccaa agagaaaatc tttgatttga agatccaagg gaaaatcggt
    16201 aagaatctag aaatcgaaga agataaacaa gcattgatgc gagggcttta tcctcatccg
    16261 cctactggac aagtagatgt gaaacaattg atctatatgc ttactgtatt tgaaagtacg
    16321 ctttatacga ctaaaaatga aatcacttta tttacagatg gtcgtgaaaa attcgatgcg
    16381 ctgatcgagg atatcaaaca ggcagaagac catatccatt tccaatatta tatttaccgc
    16441 agtgatacat taggtgaaga agttcgagag gcattgacag aggcagcaag acgcggagta
    16501 aaagtcagag tccttcttga tgcatggggt tccacacaag tttcttctag tttttttcag
    16561 aatttgaaaa aagcaggtgg agaagtcgca tttttctttc ctctattcgt tccgtatatc
    16621 aatcctcgaa tcaattatcg caatcatcgt aaaatcgtag tgattgatgg gaaaatcgga
    16681 tatacaggtg ggttcaatgt tggaaacgaa tatctaggat tggtaaagaa atttggttat
    16741 tggcgagaca atcatctgcg tatctatgga gaagcggttt acaccttgca aaaccgtttt
    16801 ttgatggact ggaattctca gcatacaaaa gaagtaggat attcaccgga atttttcccg
    16861 accattcatt ctacaggtga tatggctgtt caaatcgtga caagcggacc agataccgaa
    16921 catgagcaaa tcaaaatgac atatttgaaa atgatttcgt tagccaaacg ggagatattg
    16981 atccaaacgc cgtattacat accggatgga tcgattcatg aggcattgaa gttggctctt
    17041 ctctcaggcg taaaagtcca tatccaaata cctaacaaac cagatcatct tctcgtttac
    17101 tgggcaacgt attctttcgc tgcagagctg atcgagtatg gggcaagaat cgaaacatat
    17161 gaaaatggat ttatccatgc aaagacgatg attatcgatg gcggcatcgt ttccgttggt
    17221 tcagctaata tcgacgttcg ctcatttaga ttggattttg aagtcaatac actgatctat
    17281 gatgaacgaa tggcttctcg cgtaagaaaa gcattctttg aagattcaaa gatttcgacg
    17341 catctcacaa aagaagtgta tgaaaaccga gggatgatga tcaagatgaa agaaggatta
    17401 gcaagactga tttcgccgct cctttaaaat acaaaaagga caggagagcc atcaatagat
    17461 ggaaatctcg cgtccttttt tctcggggcc atttctgaga gtacgtcaga aatggagaaa
    17521 gcgtctcgca tgagcgaaat taactttggg gtatctcttg ttttttgggg aaagcaagaa
    17581 ataagctaat atatgctatt aaaagagaca catttcaaag ccagtatagc atagaaactt
    17641 ttaatgagat agcttttttt gcaattatga gaatttattt tgttatttaa tgattttgat
    17701 tcgttttcat caagtaatga aaatgataga ataaacatac tttaggatta aaggagattt
    17761 ctaatgaaaa aactaaaatt attcttacca ataataggat tagctattct tttatcaggc
    17821 tgttcaaagt ggattgatcg aggagaatcc attactgcag ttggctcttc tgccttacag
    17881 cctttagtag aaacggttgc tgaaacctac caggcagaaa atcctggaaa attcatcaat
    17941 gtacaagggg gcggaagcgg aactgggttg tctcaagtac agtcaggagc agtcgatatc
    18001 ggaaattctg atttgttcgc ggaagaaaaa tcagggattg atgcttcggc attagtcgat
    18061 catcgagtag cagttgttgg aatcactcct attgtgaaca aggatattgg cgtaaaagat
    18121 atcagtatgg aaaacctgaa aaaattattt acgggcgaga tcaaaaactg gagtgaagtc
    18181 ggtgggaaag atcagccagt agttatattg aaccgtgcat caggaagcgg gacccgtagt
    18241 acgtttgaaa aatgggtatt ggacggagaa acagctgttc aggcacaaga acaagattca
    18301 agcggaatgg tgcgccaaat cgttgcggac acacccggag caatcagcta tgttgctttt
    18361 tcttacgttt ccgatgatgt ggatacgttg aacgttaacg gtgtggaacc aacagatgaa
    18421 aatgtgacaa cgaacaaatg gacgatttgg gcatatgagc atatgtacac aagagaccat
    18481 ccaaaaaaac tgacaaaaga atttttagac tatatcttat ctgatgaagt acaagataat
    18541 attgtcggag agctaggcta tatccctgtt tcacatatga aagttgaacg tgattggcaa
    18601 ggaaacattg ttaaagagta atctttacac aaaatttaca aacttagcta aacttttaca
    18661 tgttattaaa accaaattga tgttcaattt gtacactgag tgagtatgtt aaacctgatt
    18721 aagggggagt catctgtgga agatgtgaaa aaagtattat taacaaaatc aaaacgttca
    18781 aaaatggaac agcgcggaaa attcattagt tttttgtgta tcgcgctgat cgtgttggtt
    18841 gtattatcta ttttttattt tgtcgctagt aaaggattgg ccaccttttt tactgataag
    18901 atcaatgtat ttgattttct gtttggtaca gattggaatc caagccaaat aggagcaaat
    18961 gggaaaccca tggtaggggc attgcctatg atcacaggtt catttattgt gaccttttta
    19021 tctgctattg ttgccacacc atttgctatt ggagcagcag tgttcatgac ggagatttct
    19081 cctaaaaacg gaacgaagat cttgcaaccg gtcatcgagc tacttgtagg tattccgtct
    19141 gtcgtttacg gatttatcgg tttatctgtt atcgtgcctt ttgtcagaag tatctttggc
    19201 gggacagggt tcggtatctt agctggtaca tttgtgttat tcgttatgat cttaccgact
    19261 gtcacaacga tgactgtgga tgcattaaag gcagtgccgc gacactatcg ggaagcttca
    19321 ttagcgctag gtgccacaag atggcaaaca atctacaaag tggtgctgcg agcagcagtg
    19381 cccggaattt taacagcagt cgtttttggt atggctcgtg cgtttggcga agccttagct
    19441 atccaaatgg ttattggtaa tgcggcatta atgccaacag gacttactac tcctgcttct
    19501 acattgacgt ccatcttgac aatgggaatc ggaaatacaa tcatgggaac agttgaaaat
    19561 aatgtgttat ggtcattagc gctgatcttg ctattgatgt cattattctt taatatcgtg
    19621 atccgtatga ttgggaagaa aggagagctg aaataatgaa cgcaaaacgc tcagataaaa
    19681 ttgctacagg tgttctatat gtggtttcag ggatcatcgt attgatctta gcagctttat
    19741 tactttatat cttagttcga ggaataccgc acatttcatg gtcattcttg actgaacctt
    19801 ccaaagccta ccaagaaggc ggtgggatcg ggattcaatt atttaactcg atttatttgc
    19861 ttttgattac catgatcatc agttttccta tctctttagg tgcgggtatc tacctttcgg
    19921 aatatgccgg aaaaaactgg ctgacagacg tgatccgtac gtctatcgaa atcttgagct
    19981 ctttgccttc tgttgttgtc ggtttattcg gtttcttggt tttcgttatt caattccagt
    20041 atggtttctc aatcatttct ggtgcattag ctttgaccgt attcaacttg cctcttttga
    20101 ctcgaacggt cgaggaatct ttacaagcgg tccattacac acaacgagaa gctggattgg
    20161 cgttaggttt gtcacgctgg gaaacagtga taaaagtggt tgttccagaa gcgacaccag
    20221 gaattttgac tggtgtgatc ctaagttcag gaagaatttt tggtgaagct gccgcattga
    20281 tttatacagc tggtcaaagc gcgccagcat tagattttac gaactggaat ccattaagtg
    20341 tttctagtcc gatcagcatt ttccgccaag ctgaaacact ggctgtccat atttggaaaa
    20401 tcaacacaga aggtacgatg cctgatggtg tttctgtttc ggctggcgct tctgccgtgt
    20461 tgatcattgc tgttttactg ttcaacttcg gcgctcgtgc gattggcaaa cgattatacc
    20521 gaaaaatgac ttcagcctaa ggagaagaag taaaatgaaa aaatataatt ggaatgaaac
    20581 aaatgtcatt accatgccaa aagataagga agttgcatta tatacgaatg atctgcatgt
    20641 ttggtatggc gacaatgaag caatcaaggg agtggatcta gaattcgaaa aaaataagat
    20701 cactgcattg attggtccct ctggctgcgg aaaatccacg tatcttcgtt ctttgaatcg
    20761 tatgaatgat gggattgcta atacgaaaat tactggaaag attatgtata aagacgtgga
    20821 tatcaatgcg cctcaagtgg atgtttatga aatgcgtaaa cggatcggca tggtgttcca
    20881 acgccccaac ccttttagca aatcgattta tgacaatata acttttgctt tgaaacagca
    20941 tggtgaaaaa aacaaaaaga aattagatga aatcgttgaa acaagcttga aacaagcagc
    21001 tttgtgggat caagtaaaag atagcttgga taaaagtgcc ttggctttat ctggcggaca
    21061 acagcaacgt ttgtgtatcg ctcgtgcaat cgcgatgaaa cccgatatct tgctgttaga
    21121 cgagccggca agtgccttgg atcctatttc gacaggaacg gttgaagaaa cacttgtaaa
    21181 cttgaaagaa gactacacga tcattatcgt gacgcataat atgcaacaag cagctcgtat
    21241 cagcgactat actgcctttt tctatctagg aaaagtaatg gaatatgaca aaacaaacaa
    21301 gatatttacc agaccaaaaa ttcaggcaac cgaagattat gtgtccggtc attttggtta
    21361 agacggaggc ctcaacatga caaaagaaat tatctcatcc aaagatcttc atctgtatta
    21421 tggaaagaaa gaagcactaa agggaattga tctaagtttc aatcaaggtg aaatcacagc
    21481 gatgatcggt ccttctggtt gcgggaaatc tacctatcta cgttcgttga atcgaatgaa
    21541 cgatctgatt ccaaatgtaa cgatcaccgg aagtgtttta tataaagaca aagacatcta
    21601 tggtccgaaa acagatgttg ttgaactaag aaaagaaatc ggcatggtgt tccaacagcc
    21661 aaatccattt cctttttcta tttatgaaaa tgtcatctat ggattgaagt taaaaggtga
    21721 aaaagataaa aaagtccttg atcaagtagt ggaagaaagt ctgaaggcag cgtccgtttg
    21781 ggaggatgtg aaagataaac tgcataaaag tgccttgtct ttatccggtg ggcagcagca
    21841 gcgtgtatgt atcgcacgtg ttttggcagt gaatcccgaa atcatcttat tggacgaacc
    21901 aacaagtgca cttgaccctg tttctactgg gaaaatcgaa agtatgctgt tagaattaag
    21961 agagcggtat acgatgatca tcgtgaccca taatatgtct caagcttcac gtatttcaga
    22021 taagacggca ttctttttag atggtcactt gatcgaatac aacgatacga agaagatatt
    22081 catgaatcca gaaaaacaag agacagaaga ttatatttca ggtcgatttg gataaggagg
    22141 aaacggaatg ctacgtacac aatttgaaga agaattgctg aatctccata atcagttcta
    22201 cgaaatgggg atgatggtga gcagcgctgt gcacaagtca gttcgtgcat acatcaaaca
    22261 cgataaaatc ttagctcaag aagttatcga aaacgatata aatatcaata atatggaaac
    22321 gcgtttggag aagaaaagtt ttgaaatgat tgcattacaa cagccagtta caactgactt
    22381 gcgtatgatt atcacggtca tgaaagctag ctctgattta gaacgtatgg ccgatcatgc
    22441 ggtgtccgtt gctaaatcca caatccgcgt aaaaggacag acgagaatac cggaaatcga
    22501 aaaagagatc tccgatatgt ccgattacgt gaaaaaaatg gtggacaacg tcctagttgc
    22561 gtatgtcaaa acagacgaaa aagatgcgcg tacaatcgcc aatatggatc aaagagtcaa
    22621 tgactatttc aatcgaatct ataatgcaac catcaaaaac atgcaagaaa atcctgaaac
    22681 agtcatcagt ggcacagact atttgaatgt tgccagctat ctagaacgaa tcggagacta
    22741 tgtgacaaac atctgtgaat ggatcgtcta cttggctaca gggaaaatca ctgaattaaa
    22801 tacgaaccac aatgagattt tctaaactga agttgtgatt ctgctgttta tttaggaaaa
    22861 gaggttgtga aatcagcgtt ttgtcctgag tattagagaa acaaacggta aaatagttcc
    22921 tcatattttg ccgttttttg agctaatacc gaaggtcagc tgattgaaca ccgtttattc
    22981 tggaaaaggg tttgtgacaa aacatgtcac aaaccctttt cattattcca atagaaagga
    23041 taaagaatgc aaaaaaagat tagcatcatc atcactctat tttttatttg tatacttgct
    23101 tcatggttta ttcagcgtca agctgctcta tatgacgtac ctgtcatcga gatcgaaaga
    23161 gtgagaatag aagaggatca acaattgatt acaggaagat tgatgaatac ggaccaaaaa
    23221 ggagaagtga tttctttaac ggctccttat caaaaaaatc aaatcgaaac agcaaatata
    23281 acaacaagac aaatctatct tgtccaaatg catggagatg aatggcaact agtagcaaaa
    23341 aaaaatgatg gctggctttt tttctttaca agtgtcttca ttggcaccat gttgcttatt
    23401 ggtggaaaac agggcgtatt tgctttagga agtctcatca tcaacatcgt tttactttta
    23461 cttttgttgc tcctctttac caaaacagaa ggtatttctc tcttaaatat agcaatctta
    23521 tttgtcgtta tagggataat cgttagtata ttggcgttag acggatggaa tagaagcagt
    23581 ataatcaaaa tttcggctgc agttacaagt gtttttttag cattttttat ttgtcttttg
    23641 acaatgaatc attggaaaga tcaaggactg cgctatgaag aactgaatta tctgacacga
    23701 ccgtatcgtt ctgtttttct ttccagcgtg ctgattggga cagctggagg gacactcgat
    23761 accgtgatca cagtcattgc gacattagaa gaattgacca agcaacaacc gaaaatatca
    23821 gcgaaacagt tatggctttc aggaaggcaa gtgggccgag atgtgattgg ttcgatggct
    23881 aatatccttt tattcgtcta tatcagcgga gcgattccat cgcttctgtt atatttagga
    23941 aatcaatggt ctttcaaaga aacggtagaa cgacatttat cattagaact tttacgcgtc
    24001 attgctggca gcttaggaat agtattatca atccccatcg cggtcctctt ttttctcgct
    24061 gtaaggaggt taaaaaaatg aatgtactta ttatacttgt tgggattttt gcaatcagtg
    24121 tgctatttgt cggtggtacg caaggtatgt atattctttt aggattattc attaatttag
    24181 gaatcttttt cctattatta ttcggctatc atcagaagtg gccgatattg gtattgtcga
    24241 ttatagggtt cctattgatc gctgtggtta tcttattttt tatcaatggt tataatctga
    24301 aaatgcgagc cgcttttgcc agtatactga tctttttgtt ttgtttccta ctattgattc
    24361 ctatcactga ttttttagcg atccaaggct ttacttcgat agaactagaa gaactatctg
    24421 gcttagataa gacgttagca attgatttta gactacttac gaggtcgttg cttctgatca
    24481 gtcttagcgg agctgtttta gatgcgagtg tagcgatttc tagtggaaca ttcgaagtat
    24541 atcaggcaaa tccgcaaatg tcttttaacc aattgcgcca tgctagcttt gccattgcta
    24601 aaaaaatatt ggcatcaaca gtgatgacgc ttctttttgc gtttatgggg agttctttag
    24661 cgttgattct ttggtttatt gacttagaca tttcttttca gcaaataatc aatgaaaaat
    24721 catttgtctt ggaatatacg atggctattc ttaccacact ggccgcacta cttgtcctgc
    24781 ccttaacttg cgtgactaca gcatatctct ttacaaaaaa gaaagaacat ctcaagatgg
    24841 agtaaaagtt acaacttaag tcctatgaca tttttactga atcagtgcat aatatggatg
    24901 taaggaaaag cttgcaaaca attttgctta aggaggcaat ttccatgaaa gaaagagaac
    24961 gtattttaga cttagtgaaa aaaggaatcc tttcgactga agaaggctta gatttattag
    25021 aaagcatggc aactgaaaaa gacgaaaaac aaatcaaaaa agaagcagac aaggtaactg
    25081 ctagtcataa agaaaaagat caggcaagtc aattgatcga tgaacttgaa aacggtgaag
    25141 aaaaaatttc tgagccagtt gatccaaaag aaaaagaaag acaagatcaa gaaaacttag
    25201 aaaagatctt agatgaacta gcaactgaag cgaataaaac ttcggcgcgt ctagacgaag
    25261 taaatgctca attcgctgac aataaggcag cacgtaatga gaaacaggaa gcattgatgc
    25321 agctgaatac aaaagaagaa ttaggcgagt tgacagaaga agaattagca cagcgtcaaa
    25381 cgttagaagc agaaatcaaa gagttagaag caaccggcga tacactatta gaagaacaat
    25441 tgaagctgga agcagaatta aaagatatcc gcaagaatca atggtctgag aaaaaagaaa
    25501 catttacgga taagtttgaa ttgccagatg attggaaaga tcaagcgaca gatacgctga
    25561 atcaagtagg cgaaaaaatg tcagaagctg gatcacagtt aggcaaattc ttgaagaaaa
    25621 cattccaaac tgtttcagaa acagtaaatg ataacatgga atggaaagat gtcagcttac
    25681 gcgtccctgg aattgcgaca acgaaatttg aacacgaatt ttattatgaa gctcctgcag
    25741 caagtatcct tgatatcaag gcagcaaacg gaaacgtgac gttaaaaacg tgggacagtg
    25801 atgatgtgaa agtggaagcc aagatcaaac tttacggaaa aatgggtgct gaaccatttg
    25861 aagcattctc tgaacggagc cagatcgagg tcaatgaaga tcatatctcc ttccaaattc
    25921 caaataagcg tgtgcgtgca gaccttgttt tctacttgcc taaacgagta tacgaccatg
    25981 cagctatcaa acttctaaat ggcaacatca tgattgagac attggaagct aaagatattt
    26041 atacaaaatc tacgaatggg aacatcatcg tgaaccaatt aactgcaacg atgctggaag
    26101 tagaaggtgt aaacggcaat atcgatattc gaaacgggaa catcttagat tctattatag
    26161 aaacagtaaa cggtacagtg acatttggtg ccacaccaga aaacctttct gtgtctttag
    26221 taaatggtga tgtacgtctt acgattaaag aagataattt gaaaaaagta gaagcaagtt
    26281 cagtgaacgg gaatgtcaaa gttgctttac cagatagcat cggtttggaa ggacacgcta
    26341 aaacaagtct tggaagcatt aacagccgtc tgtccaatta cgaagtagtt cgtgagaaaa
    26401 aagaacggac aaaccaaatg ttgcaattcc gtcgtgtttc agatgatgag atcgcacaag
    26461 tgcagctttc aacgacaaca ggaagtatct atttaaaaga tacagataaa taaagaggtt
    26521 gtgaaagaga tgttcagcct tgagcaataa gaagcgattt tttaaaatag cttcccctat
    26581 tttaaaaaaa tgtgccttat tgccgatagg ctatctcttg aacaccgatt aagaagaagg
    26641 ttgtcacaac gattttcttc atttaaaata gtagaacaga ggtgagacat gatgaaaaaa
    26701 aagttgacaa aatccaataa aaatgttgtt ttgacaggta ctttagcagg gattggggaa
    26761 tatatcggga ttgatcccac tgttatccgt gtgctttatg tattcttaag cttagttgct
    26821 tttggaagtc caatcatttt atacatttta ttagctttga ttatcccatc tgcgcgttct
    26881 gcacgaacaa actatggaca taacaatgca tattatgaaa aaaacaatta tcgtgaacaa
    26941 acaaaaaaac gcaaagaagc ggaaaaaatc gatgatgacg aatggagtga cttttaatgt
    27001 cgtactttca gcgtattttg gttaatacgt taacattcat atcgttggct gttctttttc
    27061 ctgcgatggt ccatgtgagc agtatttgga cggccgtcct tgccagcttc gtattatctg
    27121 tgttgaacat gtttgtcaaa ccgattttga cgatcctgtc cctgcccttt acattagtca
    27181 cattgggatt gtttacgttt gttatcaatg cagcgattct taaaatgact tccttttttg
    27241 taggagcaga acattttagt ttttcttcat ttggtgcagc gttattcgta gctatcttga
    27301 tgtcacttgt caatgtaatt gttagtgaac ataacagcag aaaataaaaa aagctgtgcc
    27361 gagatctcgg cgcagctttt t
//
LOCUS       DAIGUC010000041        26873 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.041, whole genome shotgun sequence.
ACCESSION   DAIGUC010000041 DAIGUC010000000
VERSION     DAIGUC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.041"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..411
                     /locus_tag="NOB46_001858"
     CDS             <1..411
                     /locus_tag="NOB46_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI1058788.1"
                     /translation="GLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAP
                     QEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLA
                     ELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            509..697
                     /locus_tag="NOB46_001859"
     CDS             509..697
                     /locus_tag="NOB46_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI1058789.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(755..1108)
                     /locus_tag="NOB46_001860"
     CDS             complement(755..1108)
                     /locus_tag="NOB46_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058790.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            1639..2061
                     /locus_tag="NOB46_001861"
     CDS             1639..2061
                     /locus_tag="NOB46_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI1058791.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2058..2288
                     /locus_tag="NOB46_001862"
     CDS             2058..2288
                     /locus_tag="NOB46_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058792.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2786..2986
                     /locus_tag="NOB46_001863"
     CDS             2786..2986
                     /locus_tag="NOB46_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI1058793.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3013..4206
                     /locus_tag="NOB46_001864"
     CDS             3013..4206
                     /locus_tag="NOB46_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1058794.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="NOB46_001865"
     CDS             complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="NOB46_001865"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI1058795.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(5898..6821)
                     /locus_tag="NOB46_001866"
     CDS             complement(5898..6821)
                     /locus_tag="NOB46_001866"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI1058796.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7017..7622
                     /locus_tag="NOB46_001867"
     CDS             7017..7622
                     /locus_tag="NOB46_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1058797.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            7930..8946
                     /locus_tag="NOB46_001868"
     CDS             7930..8946
                     /locus_tag="NOB46_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI1058798.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9087..10388
                     /locus_tag="NOB46_001869"
     CDS             9087..10388
                     /locus_tag="NOB46_001869"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI1058799.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            10434..11096
                     /gene="deoC"
                     /locus_tag="NOB46_001870"
     CDS             10434..11096
                     /gene="deoC"
                     /locus_tag="NOB46_001870"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI1058800.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            11117..11515
                     /locus_tag="NOB46_001871"
     CDS             11117..11515
                     /locus_tag="NOB46_001871"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI1058801.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            11581..12663
                     /locus_tag="NOB46_001872"
     CDS             11581..12663
                     /locus_tag="NOB46_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1058802.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            12875..14437
                     /locus_tag="NOB46_001873"
     CDS             12875..14437
                     /locus_tag="NOB46_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058803.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            14430..15563
                     /locus_tag="NOB46_001874"
     CDS             14430..15563
                     /locus_tag="NOB46_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058804.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            15563..16519
                     /locus_tag="NOB46_001875"
     CDS             15563..16519
                     /locus_tag="NOB46_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058805.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            16618..17784
                     /gene="deoB"
                     /locus_tag="NOB46_001876"
     CDS             16618..17784
                     /gene="deoB"
                     /locus_tag="NOB46_001876"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCI1058806.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            17808..18626
                     /locus_tag="NOB46_001877"
     CDS             17808..18626
                     /locus_tag="NOB46_001877"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI1058807.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            18643..19350
                     /gene="deoD"
                     /locus_tag="NOB46_001878"
     CDS             18643..19350
                     /gene="deoD"
                     /locus_tag="NOB46_001878"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI1058808.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="NOB46_001879"
     CDS             complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="NOB46_001879"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI1058809.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(20506..21087)
                     /locus_tag="NOB46_001880"
     CDS             complement(20506..21087)
                     /locus_tag="NOB46_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1058810.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="NOB46_001881"
     CDS             complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="NOB46_001881"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCI1058811.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            22222..22635
                     /gene="rpsL"
                     /locus_tag="NOB46_001882"
     CDS             22222..22635
                     /gene="rpsL"
                     /locus_tag="NOB46_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCI1058812.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            22719..23189
                     /gene="rpsG"
                     /locus_tag="NOB46_001883"
     CDS             22719..23189
                     /gene="rpsG"
                     /locus_tag="NOB46_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCI1058813.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            23283..25370
                     /gene="fusA"
                     /locus_tag="NOB46_001884"
     CDS             23283..25370
                     /gene="fusA"
                     /locus_tag="NOB46_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI1058814.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            25542..26729
                     /gene="tuf"
                     /locus_tag="NOB46_001885"
     CDS             25542..26729
                     /gene="tuf"
                     /locus_tag="NOB46_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI1058815.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
BASE COUNT         8464 a         4955 c         5695 g         7759 t
ORIGIN      
        1 ggtttatact atagccctgt tagtactcca gcagattttc ggatgcttac tcctattgta
       61 ctggagcaag cctttagaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 gtttatgcac cacaggaata tctttcacgg gcatataacg atgctcccaa atattgtgca
      181 aatatcgtaa atactcaact gaaaaataat gaggtcatta ttattggaga aattcctgct
      241 cgatgtattc aagattatcg caatgattta acttttttta caaatgggct tagtgtttgt
      301 ttagcagagc taaaaggata tcaggttacc actggcgaac ctgtttgcca gacccgtcgt
      361 ctaaatagtc ggatagataa agtaagatat atgttcaata aaataactta gtgcgtttta
      421 tgttgttata taaatatggt ttcttattaa ataagatgaa atattcttta atatagattt
      481 gaattaaagt ggaaaggagg agattgttat tataaactac aagtggatat tgtgtcctat
      541 ttgtggaaat aaaacaagac tacgaatacg agtggatact atacttaaaa atttcccttt
      601 atactgcccc aaatgtaaga acgaaacttt aattaatgtt caaaaaatga atataataac
      661 aatcaaagag ccagacgcca agacgcagag ccgataattt gagaaatgaa actctcatct
      721 tatcggctct ttttgtttat ctgaatttta ctgactagcc ttcaatattt cttgcttcat
      781 tgataccttt tgctagtgct tccattaagg atagttcttt gtctgtaaag ctatccatgt
      841 atttttctac ctgtaacctt cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt
      901 catcaataga tacatggagt aatgatacaa gatcatacag cacttgtgta cttgggtgtt
      961 gtcctttgtt ttctatattt gttaaataac gtgggtcaat ttcaatcatt gttcccactt
     1021 gttcacgagt gagaccccgt ttcattcgag cctctttaat cgctaaacca acggctctaa
     1081 aatcgtattt atcttctttt ttacgcatac taaatcacct ctatacattt tactgttcct
     1141 atataaccat aaacaggtat agaaaaacat gttatatagt ttatgagttc ctatagaaca
     1201 ctgtggaatt tattaatgcg atgaatccaa tttcaaatag aaaggtcgct gattttattt
     1261 acctatacaa ctttataaaa tttagtcata ctcctagaaa gtagataaaa ttggcgactt
     1321 aatggaggga aaagtcgcca tgagaaagat aatctgtcat ctagttctct taattaagtt
     1381 cttatcaaaa aaacttatcc acctgtactg gatagatatg accatcaatg tggttttgca
     1441 gattacatag atagaaaaat caaagcatat gaacagagaa aacaatctgt ttatgtgctt
     1501 ttttggtcac ttaataaata tcttttagga tttctcttca tttatgcaac aaatcccccg
     1561 ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac atgccactcc ctttcacgac
     1621 agaaaggggg tgaaaagcat gaaaccatct tcttttcaag aaaccataga aaatcagttt
     1681 gactatatct gcaaacaagt tattgaagat gaacgaaaag attacttcaa acatctagac
     1741 agactatcag caaaagaagt ctcgttttct gatatagata actaccttgt caactctttt
     1801 tctactgttg atacgtacgt cactgatttc caactattta aattatttgg attaagaatc
     1861 aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac
     1921 attattttac ttcattactt tatggatatg agtgatgtgg agattgcgga gttactaaat
     1981 ttgaatcgtt cgactgttta tcgtcatcga ataagtggac tagccatgat taaagaattc
     2041 atgaaggagt gtaaagaatg aaaacagctt atccaagggt tcccttcccc ctcattgtaa
     2101 aggcgacaga tggcgacgtg gaagcaatta atcagattgt taaacattat cgagggtata
     2161 cctcaaaacg ttcattacgt cgcatgacag acgaatatgg aaattctcat atggttattg
     2221 atgaaaccct acgtggcaga atggaaacga aactcatctc taagatttta tcgttcgaaa
     2281 ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg
     2341 gaggtttgtt attccatcaa agcatattgt gtgttcagta ggttttgata ggctaacaag
     2401 ccaaacgttc tttgacaacc aaataaaggc aatcgaatac gtttcggtaa gaaaagagct
     2461 gatgaactaa cacgccatga cctacaaaat tagtgagcga ttcatgttag taattcgaaa
     2521 gtaatcttta gcaggattgc tgccatgact ttcttatcgt gataatgata ctcccgtata
     2581 gccatagtcc gagcgttaga agcgtcacag gcaatgggta cggctacatg agaaccatgc
     2641 agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat tgctaagata ttcttctctt
     2701 gtcagtgtat tattataaaa ctatttgata taattatagg tgaatattgg agttttccta
     2761 gcctataatt gggaaaggag taataatgat aacggtcaca aaaaaggatt tagttgagct
     2821 aggatatgga acttcttttt cagcagacat cataaaaaaa gcaaaagaat tgatgattac
     2881 aaaagggcat atctactatc aatctcgaaa gctagataga gtccctcgtg aagctgttga
     2941 agaaattcta ggaattcggt tttcaaatga aaacaggtct gagtagtttt tgcacagtaa
     3001 ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa agaatggaac ctattatttt
     3061 cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc
     3121 actactaaaa aagaagcaag agaagaatat tcgaaactgc tattgatgaa accagaagaa
     3181 ttaagtgaga ataaggataa aatgacgttt aaacattata tctttgaaat tttccttcca
     3241 tggtataaga cacaggtaaa gctcagaaca tatgaaaatc gcttaccaac tattaagaag
     3301 catttctctt attttgataa aatggctgtt tccgatattg agcctattga tgtgcaaaat
     3361 tggcaactaa aattatcaaa gaagtgtaag tcttcttatg taagagctgt tcaaggacta
     3421 ttttcagttg ctatggatcg agcaattgtc cttgggataa ccaccacaaa tccatctaag
     3481 attattggca atgtgaaaaa gcaaaagtct aaaattgaat tttggacaaa agaagaattt
     3541 gaaaaagtaa tctctctaat ttacaaagaa gattactatc aacacttttt atttatctct
     3601 ctgtggtttt tatttatgac tggaatgcga attggtgaag ctactgccat tcaatgggaa
     3661 gatattgatt ttgactcagg agtactaacc atcaacaaaa cactctatta caagaatcaa
     3721 tcgaattata gatttgttga accaaaaaca aaggcgagcg ttcgtcatat tgtattagat
     3781 aaatgcacat taacttattt atccgaatgg aaggaagtac aacaaaatct aattcagaca
     3841 gactttgtaa tgagctataa cggtattcct acccaaaaac atacactatc atatgctatt
     3901 gaacgctatg ctaagctggc tggtatccat cgaatcagaa tccatgggtt acggcattct
     3961 catgcttcct tgttaatcag tatgggagaa aatccactta tcattaaaga tcgtctagga
     4021 cacgaagata ttgagacgac tttaggaacg tatggacatc tttatcctaa cagtaatttc
     4081 gaggtagcta acaaattaaa tggagccatt tcctttaaag aagcaaaaca aaattatgat
     4141 acttcaccaa agaatcaatt tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg
     4201 caataaaagt gcagtaaaaa gataagaaga gccagaaacc cttggtataa gaggatttct
     4261 agctctccta caactattcc cactccactg ttgctggtgg tttagaagtg atgtcataca
     4321 cgatacggtt gacgtgggct acttcgttta cgatacgtac agagattttt tgcaagactt
     4381 cccatgggat acgggcaaag tcagcggtca ttccgtcgat tgaagttaca gcacggatac
     4441 cgactgtgta gtcgtaagta cgtccgtcac ccataacacc gacagagcgg atccctggaa
     4501 gaacagtgaa atattgccag atatcacggt caagtccagc agctgcgatt tcttcacgca
     4561 agatagcatc agattcgcgt acgatttcta gcttgtcttc agtgatttcg ccaagaacac
     4621 gaataccaag accaggacca gggaatggct gacgccaaac gattgaatca ggcatgccta
     4681 actgagtccc taattcacgg acttcgtctt tgaataatgt gtttaatggt tcgatcaatt
     4741 caaattgcat atcttctggc agtccaccta cattatggtg agatttgatc gtctgtgctg
     4801 tttctgtacc agattcgata acgtcagtat acaacgttcc ttgtgctagg aaagagacgc
     4861 cttcttcacc agcaagtttt gttgcttcgt catcaaaaac atatacgaat tcattcccaa
     4921 tgattttacg tttttgttct gggtcagata cacctttcaa cttgtctaag aagcgatctc
     4981 ttgcatcgac tttgatgatg ttcaagccga attttccgcc tagactttcc attacttgtt
     5041 ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat agatgtcaat tggtcaccga
     5101 tcgctttttg taaaagaacc ccaacgacac tagaatcaac gccacctgaa agaccaagca
     5161 agactttttt gtcaccaact tgttcacgga ttttttctac ttgcatatcg ataaagttat
     5221 ccattgtcca gttaccttca cagtgacaaa catcaaaggc aaagtggcgc agcaattcga
     5281 ttccgtattc ggaatgacgt acttctgcat ggaattggat accataaaaa ttacgtgttg
     5341 tgtcttggat agaagcaatc ggacaatctt tgcttgttcc gactgtttca aagccttcag
     5401 gaactttagt taccaagtca ccatggctca tccatactgt ttgttgtttt ggtgtttctt
     5461 taaacaagac agcttgatcg cttgttactt ctaacaaggc tttcccatat tcgcggtttt
     5521 tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc
     5581 ctaatacagg aatacctaaa ttgaagatct caggatcgat cccaaatgca ttctcatcat
     5641 atacactgtt tggtccgcca gaaagaatga ttccctttgg attcatcgct tttacttctt
     5701 ctgcagtaat gcggtggctc aataattcgg aaaagactcc aagatcacga atacgtcttg
     5761 tgatcaattg gttatactga ctaccgtagt ctaatacgat aatcttttca acgttcgtca
     5821 tatcggcaac gtttgtcaaa tttattaccc ctatcccttt aaattttatc tcaaaatagt
     5881 caaactattt taaaatgcta atattttcgc atgaaaatcg aatcgatgat atgattttca
     5941 gttttatgga gaattatatc ggctcttcct cgtgtaggca agatatattc ctgtaaattt
     6001 ttcaaattca catttttcca tacatctttt gccattttaa aggcttcttc acgatctccg
     6061 atagcaaaac gataataata attctctgga ttttggaaag ccgtatccag taacgcacca
     6121 aaacgatcca aataccattt ttcgatcagc acgggatcgg catcgacata gacagaaaaa
     6181 tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta attgaagcgt attgatcccc
     6241 tcaacgatca agatatcagg ctgctggatc aattcgtact tgtctggaat gatatcatac
     6301 acatcatgtg agtaaacagg tacttttatc tcttcctgac cagattttac acggttcaag
     6361 aaatcgatca gcatctccat atcataactt tcaggaaatc ctttacggtc catgattcca
     6421 cgctctttta atatacgatt tggataaaga aatccgtcag tcgtgatcag ctgaacgttt
     6481 cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc tggctgttgt actttttcca
     6541 acggctacac ttccggcgat cccgataata aaaggcggta cttctacgta tttatgaaga
     6601 aataaacctt tactcaagaa caaagattca aattctttca tataaagata aatcagatga
     6661 gcaagaggta catagatatc tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg
     6721 atattatcta gttcatcttg tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat
     6781 tcttctcttg ccacacggta gtagttcatt ggatcattca tattagcctc ctgcgttctc
     6841 ccatcaatgg aactatttta acacaaaata aacgcaaacc ccaccactta agagagattg
     6901 ccgatctttt tgtataatct ttataataga aagaaacgga gtcttattct tgacttgcgc
     6961 acggatacat aaaaggatag actgttgtca tgaaagaaat gagaaggatg gaagacatga
     7021 caaatcatta ctattctgaa cgcccagata cggcgcacga ttttgaacaa tgggcttttg
     7081 agttaaaagg cagaaccttt caatttgtaa cagattctgg tgtattttca cgtgaaacag
     7141 tggattatgg ttcacgtgtc ctgattgatg ctttcgattg ggaagagtta cctgatgaag
     7201 gaaagatctt agatgtggga tgcgggtatg gaccgattgg gttagctttg gcatttgcga
     7261 cacagcggtt tgttgaaatg gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa
     7321 acgcaaagcg taaccaaatc gaacatgttg atatccatca atcgaatatc tatgaagcag
     7381 ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag
     7441 ttgtacatga aattttgaca ggcgcatatc ctcggttgaa gaagggcggt acactgacaa
     7501 ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg
     7561 gtaatgcaga aatcgtcaca aaagataaag gatattatat catcaaaagt gtgaaagaat
     7621 aactagctga aaaatagtgg agcgacgaaa gagtggaact gggcgtgcat gtacgggtac
     7681 gtatcagttc tttttttgtt gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa
     7741 agaaatagta ggaacagagt cgttgttttt tacgataaaa taaataagat acagaacttg
     7801 tatagaaggc tgccaagtcg gtagataaag gaggttttta tcaaaaaaca tactttcctt
     7861 ttttctctat tcttttcttg ggggttttgg tacactgata gggaatttag atagaaggga
     7921 gccaatagga tgaagctgac catcagagat atcgcagaaa tggcaggcgt atcagtaaca
     7981 actgtctcac agattttgaa taacaaagga agcagattta gtgataagac aagaaaaaaa
     8041 gtgttgtcga tcgtgaatga acatcattat aagcccgatt atttcgcttc aaatgtgatc
     8101 aatcgacatt caaagaccat cggaatgatc gtccctgatg tcactgattt cttcttctcc
     8161 aaactgatcg aaggtgtaga gagctatttg aatcctttgg gctatgtgat catgttatgc
     8221 aattctcgtc atagccaaga aaatgagatc aagtatttac aagagctttc ccaccgctca
     8281 gtggacggaa tcttgctggc cacaccaaat attttacctg agaaatatgc attagacagc
     8341 ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg gattgaatcg tcgggataac
     8401 ggacggctta tcgtaaagga atatgagggc gcctatcaag ctgtttcgct gtttattgaa
     8461 aatggccata cgaagatcgg catgctgaag gaaaccactg gatactatca attagaagaa
     8521 cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt
     8581 gttgaacatg gagagttgac tgtccaaggt ggatatactg catcaaaaaa attactcaaa
     8641 cataaagata tcacggctat tttttgcggg aatgatgcca tggcgatcgg atgctatcag
     8701 gcgatcgatg aattgggcaa aaaaatccca gaagatatct cagtcatagg attcgatgga
     8761 ttaaagctgt cagaatacat gattccgcaa ttgacgacag tgcagcagcc aagttttgat
     8821 attggatttt atgctgcacg tttcctgatc gatacgatcg aatttcctca aagaaaagtt
     8881 ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga gcgtaaaagt attgacaaag
     8941 ggctaactcg gcggtatatt gcttatgtaa gcatttacaa aggctagtta gtgctttttt
     9001 tatttttagt aaaccagttt actaaagtgg tttacctttc ctaaaaataa tgtataatac
     9061 cgaatgaaga caaggaggat caggcaatgc gaatggtgga tctgattgaa aaaaagaggg
     9121 atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt cacgaactat acgaatggaa
     9181 agattccaga ttatcaagtc agtgcattat tgatggcaat tttttatcaa gacatgacaa
     9241 atgaagaaat cacgaactta acattggcga ttgctaattc tggtgatgtc atcgatttga
     9301 gttctcttga aggaataaag gtagataagc attcgacagg tggcgttggt gacacgacca
     9361 cattgatttt agccccccta gtagctagtg tcggagtgac agtggctaaa atgtctggac
     9421 gcggtctagg ttacacaggt ggtacactag acaagctaga agcaattccc ggatttcaga
     9481 tcgagctttc ggatgaagaa tttgtacgca ttgttaatga aagtaaagta gcggtaattg
     9541 gtcaatcagg aaacttggca ccggcggaca aaaaattgta tgccttgcgt gacgtcacag
     9601 cgaccgttga ttctcttccg ctgattgcca gttcgattat gagtaaaaaa atcgcggcag
     9661 gagcagatgc aatcgttttg gatgtgacca ctggagacgg tgctttcatg aagaacatcg
     9721 aagatgcaag acgtctggca aagaccatga cgagcattgg gaaactggct aaccgagaaa
     9781 cagtggcggt tatctcagat atgtcagaac ctcttggcga agctatcgga aatagtctag
     9841 aagttgtcga ggcaatcgaa acattacaag gaaatggtcc agaagatcta gtagaaatgt
     9901 gctacgcctt aggaagccaa atggttgttc ttgctggcaa agctaagaca accgatgaag
     9961 caagaacgtt gcttcaagaa gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa
    10021 tgatccaaaa tcaaggggga gacccagcga tcgtggaaca tccagaacga attttgactg
    10081 cacgctacac aatggagctt cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa
    10141 atgaattagg aattgctgca atgatgctag gtgctgggcg taaaaccaaa gaagaagata
    10201 ttgatcacgc tgttggattg aaactgcata aaaaaattgg tgacactgtg acaaaaggtg
    10261 agtcactatt gacgatctat agtaacgacg aagaaatcac ttctgtcatt gaattattat
    10321 ataaaaatat tgaaattggt gaatcggcaa tgaagccaac gttgattcat gacatcatca
    10381 cagaataaag gaaaaaagcg gactttaccg ttttaaagaa aaggggaaaa gaaatggaac
    10441 taaaccgaat gatcgaccat actattttga aagcagacgc atctaaagaa gctgtgatgc
    10501 aaattatcga agaagcaaaa aaataccatt tttattctgt ctgcatcaat ccagcatggg
    10561 ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt
    10621 ttcctctagg agcaaacaca cccgagacaa aagcatttga aacaacagat gccatcaata
    10681 acggtgcaga tgaagtcgat atggtcatca atatcggtgc tttgaaatca aaggatgatc
    10741 aacaagtcca aaaagatatc gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca
    10801 aagttattat tgaaacatcg ttattagata gagaagaaat catccgagct tgcgaaatag
    10861 caaaagctgc aggcgctgat tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa
    10921 aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt
    10981 ccggcggtat ccataacgaa gaagaagcaa tggcaatgat cgaagctggt gctacaagaa
    11041 tcggaacaag cgcaggagta gcaatcgtat ctggttcaac tggtgaaggc tattaatttt
    11101 ttcaaaggag aagctcatgg cagaactcaa acaagaatgg atcaacacag ctattgaagc
    11161 gttagataaa gcctatgttc cttattccca ttttccggta ggcgcttgtc tcgtaacgga
    11221 atcaggcaag atttatcaag gcatcaacat tgagaatgca tcatttggat taacgaattg
    11281 tgccgagcgc acagcttttt tcaaagcagt atctgaagga gaaaaaacat ttacgcatct
    11341 agtcgtagcg gggcacaccc ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat
    11401 ggcagaattc tgttcccctg atatgccggt tacgctagta ggagacaatg gtgtgacgaa
    11461 ggcaacgacc gttcgtgcac tgctgcctta tgcatttact gaaaaagatc tataactcat
    11521 gttcattcag tcagctgact gttgaaaaat aaaacaatta ttttaggagg ctttacagaa
    11581 atgaaaaaag caaaattatt tggtttaggt gctgtcgcac tagcagcagg gttattttta
    11641 ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg gcaaaagctc atcagacaca
    11701 acaactgcag cattgatcac agacacaggt ggtgtagacg accgttcatt caaccagtca
    11761 gcttgggaag gactagaaaa atgggggaaa gatcaaggac tttcacgagg aaatgatggc
    11821 ttccaatatt tccaatcttc aaatgaatca gattacatcc caaatattga ccaagcattg
    11881 aatgctggat tcaaaacgat ttttggtatt ggttataaac taaaaccagc gatccaagaa
    11941 caagcaacaa acaatacagg tacgaacttt gttattatcg atgatgtcat cgatggatta
    12001 gataacgttg tatctgcaac tttcaaagac aacgaagctt cttatcttgc aggtgttgca
    12061 gcagcttata cgactgaaac aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta
    12121 atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg caggtgcgaa agaattagga
    12181 aaagaaatca aagtattgaa tcaatatgct ggtgacttct ctgctccaga taaaggacgt
    12241 tcaattgctc aaggtatgta tgcacaaaac gcagatatca tcttccatgc ttcaggcggt
    12301 acaggtaacg gtgtattcca agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt
    12361 tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg aatacacatt aaacggcgaa
    12421 aagaaaaact tcacattgac atctacactg aaagcagttg gaacagtagt agaagatttg
    12481 gcacaaaaat cagcggacgg taaattccct ggcggcgaac acactgttta tggattgaaa
    12541 gaagacggtg ttggtctaac agaaggacaa ctttctgacg aagcgaaaaa agcagttgat
    12601 gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac
    12661 taaaaccatt tctatagcct tgttagacac atgtttgaca aggctatggt ttgattagaa
    12721 caagaattgt tcatttatcc aagctgcctt gtgacagttt ggataaggga acaactccct
    12781 gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg tgaatcttag tcaatcgttg
    12841 ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga
    12901 aatgcagaat attaccaaag aatttggaac attcaaggca aatgacaaca tcaatttaca
    12961 agtaaaggca ggagaaattc atgcgttgct tggagaaaac ggtgctggca aatctacatt
    13021 gatgaacgtg ctttccggat tattagagcc gacatcaggg aaaattttga tgcgtgggaa
    13081 agaagtaaag atcacaagtc cgaccaaagc caaccaatta gggattggga tggtccatca
    13141 gcactttatg cttgttgatg cctttactgt aacagaaaac atcgtgttgg gaagcgagcc
    13201 tagtcgcgca gggatgcttg accataaaaa agcacgaaaa gagatccaaa aagtttctga
    13261 acagtatgga ttgtcagtca acccagatgc ttacgttcgt gatatttcag ttggaatgga
    13321 acaacgggta gaaattttaa aaacacttta ccgaggagca gatgtactga tttttgatga
    13381 gccgacagct gtattgaccc ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt
    13441 agtcaaagaa ggcaagtcga tcattttgat tacgcataag ttagatgaaa tcaaagcagt
    13501 agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga
    13561 cgtaacctca caacaattag ccgatatgat ggttggaaga acggtttcat tcaaaacgat
    13621 gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga
    13681 aaatcgtgga ttagaagccg tgaaaaactt gaacttagag gttcgtgctg gcgaagtact
    13741 tggtatcgct ggaatcgatg gaaacgggca gtcggagttg atccaagctt tgactggttt
    13801 gcgaaaggca gaaagcggac atatcaagct aaaaggggaa gacatcacta ataaaaaacc
    13861 ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt
    13921 agtcctagat atgacattat ctgaaaatat cgcactacaa acctatcatc aaaaacctta
    13981 cagtaaaaac ggcatgctga attattcagt aatgaatgaa catgccagag aattgatcga
    14041 agaatatgat gttcgaacaa cgaatgaact tgttcccgca aaagctttat caggcggaaa
    14101 tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc
    14161 aaatccaact cgtggactgg atgtaggtgc gatcgaattt attcataaac gtctgatcga
    14221 acaaagggac aaatacaaag cagtgttact gatcagtttc gaattagaag aaattttaaa
    14281 tgtttcggat cgtattgctg ttatccatga aggagaaatt gtcggtatcg ttgatccgaa
    14341 agaaacatct gaaaatgaat taggtctatt gatggcgggc tataccttag aagaagcacg
    14401 aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt
    14461 tattagtgcc tgtactttca gttgttttag gattgatctt aggcgcgata ttgatggctg
    14521 cttttggttt tcagcccatc caaggttatt cttctatgct agatgcagcc cttggttcgc
    14581 aaagagggat aggtgaaacg ttaaggcaag caacgccgtt gatttttaca gcattaggtt
    14641 tttctgtagc taactcagct gggtttttca atattgggct ttctggacaa gcactttgcg
    14701 ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga tctgccaaaa gttgttttgc
    14761 ttccgttatg cgtgatctta ggtgccttag ctggtgcgat ggcagcggct gttccaggtt
    14821 tacttcgagc attttttgga acaagtgaag tgatcgtaac aatcatgatg aactatatct
    14881 tattatacgt aagcacattt gctttacatg aagtgatgcc tgaaagctat cgctcaagtt
    14941 tggactcttc caatatgatc agtcaaaatg cctcactgcg gttaccatgg ttaacacaag
    15001 cttttggcgg ctctcgcgta aactcaggat tatttttagc aatcatcgcg cttattttcg
    15061 tttggctgct gatgaagaaa acgactttag gatttgaaat ccgttctgtt ggattgaatc
    15121 cttttgcttc tgagtatgca ggaatgagta gtaaacgtac gatcgttttg tcgatggtca
    15181 tttctggcgc tttggcaggg cttggcggtg tggttgaagg attaggaacg tatcaaaact
    15241 tctttgttca aacgacttcg ctatctattg gatttgacgg aatggctgtt tccttgcttg
    15301 gttctggatc agcaatcggt attcttttat cagcgatctt gttcagtatt ttgaagatcg
    15361 gtggacttgg catgcagaca ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg
    15421 ctttgattat cttctttgtc gggatcaact tcctgattcg tttcgtcatg gctaaagtct
    15481 tccaagggaa aaaacaagaa gagatcgttg cgacaataga atcgaaacca acgaatcaaa
    15541 accatgaagg gggcgaacta taatgtcgac tatcgaatta attgccttga tccttacttc
    15601 tacactggtt tattcaacac cgctaattct aacgtcacta ggcggaactt tttctgaacg
    15661 aagcgggatc gtaaacgtag ggctagaggg aatcatggtc atgggtgctt ttagttccat
    15721 cgttttcaac ttgacgatga gtccatcact tggttctatg acaccatgga tcgctatttt
    15781 agtgggtggc gtcgtaggta tcctattttc tctgattcac gcagtagcaa cagtcagttt
    15841 gcgtgctgac catattatca gcgggacagt aattaatctg atggcacctg ctttaggtgt
    15901 tttcttgatc aaagcatggt atggtaaagg tcaaactgat aacatcacgc agaatctggg
    15961 gtatttttct ttcccaggat tagcagatat tccggtcatt ggaccaattt tctttaaaaa
    16021 tacattctta cctgcttatt gtgctatttt gattgctgtc ctagcttggg tgatcatctt
    16081 caagacgaaa ttcggcttgc gcctccgttc agttggtgaa aatcctcaag ctgccgacac
    16141 attaggtatc aatgtatatg ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg
    16201 cggtatgggc ggtgctgttt ttgctcagtc gatttccggt aacttttcag ctggtacgat
    16261 cgttggacaa gggttcatct ccatggctgc tatgatcttt ggtaagtgga atcctttagg
    16321 ggcaatgggt gcctcattgt tctttggttt tgctcaaagc ttgagtatca ttggcgcaca
    16381 attaccagtt atttcttcga ttccgccagt attgctgcaa attgctccat atttgctgac
    16441 aatcattgtg ctggttgttt tcttagggaa agcttctggt ccaaaagcaa acgggaagaa
    16501 ctatatcaaa tcaaaataat cttttagcga ataaaaaggg tgggttacgg gaagtgtttt
    16561 tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa agaaagaagg aataatcatg
    16621 tttaaacgcg tacatctgat cgtcatggat tcagtaggaa ttggagaagc accagatgcc
    16681 gataagttcg gtgatgttgg ttctgataca ttaggacaca ttgcgaaaga agcaggattg
    16741 aacgttccac atttagagca gcttggttta ggaacgatcc gtcctcttga aggtgtggaa
    16801 tcagtgaaag atcatcaagg ctatgcgacg aaattagaag aagtttctgt agggaaagat
    16861 acgatgacag gccactggga aatcatggga ttgaatatca aaactccatt tcgtgtgttt
    16921 cctaatggat tccctgatga tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc
    16981 gtatgtaaca aaccttatag cggaacagct gttattgacg attacggtga acaccaaatg
    17041 aaaacaggcg atttaattgt atatacttct gccgatcctg tccttcagat cgcggcacat
    17101 gaagaaatca ttcctttaga agaattatat cggatttgcc aattcgttcg tgatataaca
    17161 aaagatgatc cgtatatgat tggccgaatc attgcacgtc cgtacgtggg tgaaccagga
    17221 gacttcacac gaacaagcaa tcgccatgat tatgcgttga atccattcgg acacacagtc
    17281 cttgattctt tgaaagaagc aggaaaggac gtgattgctg ttggaaagat caacgatatt
    17341 ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac
    17401 cagctgctga aagttatgaa aaacgatttt tcaggaatca gctttaccaa tttagtagat
    17461 tttgatgcat tatacggtca tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa
    17521 tttgacttac gaattccaga attgcttgaa gcgatggaag aagacgactt gctaatgatt
    17581 acagccgatc acggaaacga tccgacgttt actggtaccg atcatacgcg agaatatgta
    17641 ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg cattgcctca aggatattat
    17701 tcagatattt cagcaacgat tgctgagaac tttagtgttt cttcgactga aaatggcgaa
    17761 agcttcttga aattattaaa ataatctttt taaataggag aaagcaaatg accaagttaa
    17821 gcgagatgtt acaagaaacg acccagttta tccttgataa aggagtaaaa gaaattgatt
    17881 ttggtttgat tctaggttca ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa
    17941 tgatttctta tgatgagatc ccgttctttc ctgtttcgac agtagttggg catgcaggaa
    18001 agctagttta tgggtctctg gcaggcaaga aagtgttagc catgcaaggg agattccact
    18061 actatgaagg tcattccatg caaacagtga cctatccagt acgtgtgatg gccggactag
    18121 gggcccattc agtcattgtg actaatgcat gtggtggtgt caacgaatca tttgtaccag
    18181 gagatttgat gctgattacc gatcatatca attttactgg tgaaaatcct ttgatcggtc
    18241 cgaatgaaga tgcaatgggc cctagatttc cagatatgag tcaagcttat acgcctgact
    18301 atcaagcaac agcaaaagca gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat
    18361 atatgggcta ttctggacca acttatgaaa cgcctgcgga gatccgaatg tctcggacaa
    18421 taggagccga tgcagtaggg atgtcgactg ttccagaagt catcgtagca gctcacagcg
    18481 gattaaaagt gttaggaatc tcttgtatta ccaacttagc agcaggtatg caagcgaatc
    18541 tgagccatga agaagttgta gaaacaactc agagagtcaa acaatctttt aaagcattgg
    18601 ttaaagaaac attgacatta ttgtaatagg aggaacaata aaatgagtgt gcatattgaa
    18661 gcgaaagaag gcgagatcgc cgataagatt ttacttccgg gagatccttt gcgagctaaa
    18721 tatattgcgg agactttttt ggaagatcca gtttgttaca atcaggtacg cggtatgtta
    18781 ggctttaccg gcaaatataa aggagaacgt atttctgttc aaggaacagg aatgggaatg
    18841 ccatcagcca ccatctatgc ccatgaattg atccagtcgt atggtgtaaa gaaattgatt
    18901 cgagtaggta catgcggtgc attgtcaaaa gacgtccatg ttcgtgattt agtactagca
    18961 caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct
    19021 ccaatcagtg atttcaatct attactgaaa gcatatgaga tagctaaaga aaagggctat
    19081 acggttcatg taggaaatgt tctttcggaa gattctttct acaaagatga tttgacagag
    19141 acgttccaat tagctgaact tggcgtttta ggagtggaaa tggaagcagc ggctctttat
    19201 tacttaggcg cgaaatacca tgtgcagaca ttaagtttga tgaccgttag cgaccatttg
    19261 atcaccggtg aagaaacaac agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa
    19321 gtaggattgg aaacagcgat agcagaataa gaaggaaatg aaaaagctgc cctgcattaa
    19381 gtaataagaa catccaagca aaaatagctc ctcatgtttt tgacttggct ggacttatta
    19441 ttgcaaatgt aagcttttga acaccgttta ccaagaggtt gtgaatctgc cgtttaactc
    19501 tgagtcacaa ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg
    19561 tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa aagggactgt gacaaatcgt
    19621 gtcacagtcc cttttttata gtgtttttta taggtagtat tttttagcaa ctgttaagtc
    19681 atcatttaat tcataaacaa gtggttgacc tgttggaatt tcaagatcca tgatgtcttc
    19741 gtcagagata ccttcgatat gtttagctag ggcgcgtaat gagttaccat gtgcagctac
    19801 taaaacagtt ttgttgtcta gtaatgctgg agcaatttca tcttgccaga atggcaaagc
    19861 gcgttctaat gtcactttca agttttctcc accaggaata tcgcgtttgt ctaacattgc
    19921 gtaacgacgg tcatttgctg cagaaccttc gtcagtttct tccattaatg gaggaagagt
    19981 atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg tatttttcag ctgtttcttt
    20041 tttgttcaaa ccttgtaatt taccatagtg acgttcgttt aagcgccatg atttgatttg
    20101 tggtacccaa agttgatctg aatattctaa gatcaagtta catgttttga ttgcacgagt
    20161 taaaacagaa gtgtaagcaa catcaaattc gattccagct tctttgattt tgcgtccgcc
    20221 ttcttttgct tcttcgattc cttctggtgc tagatttaca tcagcccaac cagtaaattg
    20281 gttcaatgca ttccattcac taagaccgtg acgagaaaaa actaattttg gcatgtttag
    20341 ctctcctttt aagataggtt tatatttctg aaattttcag ttctgtttta ttgtacaatt
    20401 ttttggaaga gatttccatc gaaaaattag ataagattct atgagaaaac aagtagagaa
    20461 tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt aggtattaga tgcataattg
    20521 ctcgatttct ttttcaggta aattgatata tttataacat gttccaactg aaacaccgca
    20581 ttttgaagaa ataaattgga tcgtttcttt tttttcataa tagagacgtc ggattttttt
    20641 gatcgttttt gcatcgattt ttggtcttcc gccgattttt ccttttttac gagcttcatc
    20701 taatccaact aatgtacgtt ctttgatcaa tgcgcactcc atgtttgcta ggttttccat
    20761 taattggaaa tagatttttc ccatttcgcg cgtatcgatt ccttcatcaa gactaatcaa
    20821 gtgcagcccg cgatctttga ataattgcgt gagttctgtt aattgccgcg tagatttgcc
    20881 taatcgatga agttggcaaa tgactagtgc atcgccttgt tgcatgtcag cgatcactga
    20941 ctccaaatga acagcagtag aatcattttg ttccacttca tatgtctcat ggaaaatttc
    21001 ttgacaacca aagtcagata attgatcaac ctgagttgtt aaatcaacgt catttatggt
    21061 tgtgcgtgca taaccaataa ttttcatggt gattcctttc tagcagtgat tttctaactg
    21121 gatataacag taaaaatgta gcataaagta cgtcaaaaag atagtttttt cgcaaatttt
    21181 ccgctgtctt tttttattgg atgatcaagc agtttttctt tatttacgac ggattgcgtc
    21241 aagaatctca acgccttttt ctgagccgac aactacttta gaaaccatgt ttaggaaaag
    21301 cccatgttct actaccccaa caagttcatc taaataggta gctaagcttt ctggctgttc
    21361 gatgacttct agatgcagat caatgatgta atgaccacca tctgtggtta agacttctcc
    21421 gttttcgtct gtacgcaaga cgggttggaa tcttttttct tcaaaaatat gaagtagctg
    21481 ttgggagcca taagggatca cttcaactgg gagtgggaac ttcccaagtt tatcgactaa
    21541 tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac gtagcgacta ttttctcgaa
    21601 aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca gcactgattt catcagcacc
    21661 gtctattgtc aaatcgacta cggggacttc atcaatactc tttaacggta ttcctaattt
    21721 ttccgcttgt tcttttgtcg catttgaagt agtaactcct gtgatacgta aaccttcttc
    21781 acgcatacgg cgaccaatct cttctaccat ataataggcg gttgaaccgg tcccgagacc
    21841 tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg ccagctaatt gttttaaatt
    21901 catctttgcg tccacctttt tttagtttga gcatcgtgct ttcctcacta ttttagcgtg
    21961 atttacggta aaaagatacc attctttttt attccaataa agctttttca aaaaaaattg
    22021 catctcttgt tgacatgttt tttcattcgt gatattctaa caaaggtgct ttatctacag
    22081 gtttctgtga agaaacgtgc tgactgttta tcaaagcata tttgataagg atgcagacat
    22141 tgcatttatt ttttatcaca aaaaaagaac cacctggatg tgtggaacta gacgcaaatc
    22201 gtgggaagga ggaaacaagg aatgcctaca attaaccaat tagtacgtaa acctcgtaaa
    22261 tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag gatataacag ctttaagaaa
    22321 actcaaacta acgtaaactc acctcaaaaa cgtggggtag caactcgtgt gggtacaatg
    22381 acacctaaaa aaccgaactc agctttacgt aaatatgcac gtgttcgttt gtcaaactta
    22441 attgaagtta ctgcttatat cccagggatt ggtcataact tacaagaaca cagtgttgta
    22501 ttattacgcg gtggtcgtgt aaaagactta ccaggggtac gttaccatat cgttcgcggt
    22561 gctttagata ctgctggtgt taacgaccgt aaacaaagcc gttctaaata cggaactaaa
    22621 aaacctaaag cttaatttta attattaaac aaatgaaact tgcttctact atatagaagt
    22681 aattactatg aacaatattt cggaaggagg agttacggat gccacgtaaa ggtcctgttg
    22741 caaaacgtga tgttttacca gatcctattt ataactcaaa attagtaact cgcttgatca
    22801 accgtgtaat ggttgacgga aaacgcggga ttgcagctaa cattatctat aatgcctttg
    22861 acttgatcaa agaatctaca ggtaacgatc cattagaagt gtttgaacaa gcaatgaaaa
    22921 acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg gggttcaaac taccaagtac
    22981 cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct tcgttgggta gtaaactacg
    23041 ctcgcttgcg cggtgaacac acaatggaag aacgcttagc aaaagaaatc atggatgctg
    23101 caaacaacac aggtgcttct gttaaaaaac gtgaagacac tcataaaatg gctgatgcca
    23161 accgtgcgtt tgctcactat cgctggtaag attctctctg tttggtcggc ttttataagt
    23221 cgacctcaga tagtgtcctt atttttagca actagatagt aaagagagga gaaacaagga
    23281 gaatgaccag agaattttct ttacaaaaca ctcgtaatat cggtatcatg gcccacatcg
    23341 atgctggtaa aacgactgct actgaacgta tcttatacta tactggtaaa atccataaaa
    23401 ttggtgaaac tcatgaagga gcttcacaaa tggactggat ggaacaagaa caagaacgtg
    23461 gtattacgat cacttctgct gctactacag cacaatggaa gggtcaccga atcaacatca
    23521 tcgacacacc aggacacgta gacttcacag ttgaagttga acgttcattg cgtgtacttg
    23581 atggtgctgt aactgttctt gatgcacaat caggtgttga acctcaaact gaaacagttt
    23641 ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt tgcaaacaaa atggacaaga
    23701 tcggtgctga cttcttatat tcagtatcaa ctttacatga ccgtttgcaa gcaaacgctc
    23761 acccaatcca attaccaatt ggtgcggaag acgacttcac aggaattatc gaccttgtaa
    23821 caatgaaggc tgaaatgtat acaaacgatc ttggaacaga gatcgaagaa acagaaattc
    23881 ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa attggttgaa gctgtagctg
    23941 aaactgatga agaacttact ttgaaatact tagaaggtga agaaatcact gaagctgagt
    24001 taaaagaagg tatccgccgc gcaacagtta acgtagaatt ctacccagta ctatgtggtt
    24061 cagcatttaa gaacaaaggg gttcaattac tattggacgc tgttcttgat tacttgccat
    24121 caccgttaga tatcccagct atcaaaggga ttgaccctaa aactgatgaa gaagtagaac
    24181 gtcctgcaga cgacagcgct cctttctcag ctttagcatt taaagttatg actgacccat
    24241 tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt tttacaatca ggttcatacg
    24301 tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg tatcctacag atgcatgcca
    24361 actctcgttc agaaatctct gaagtttacg ctggagatat cgctgctgct gttggtttga
    24421 aagacacaac tactggggac acactatgtg atgaaaagag tctagttatt cttgaatcca
    24481 tggaattccc agaaccagtt atccaagtcg ctattgaacc taaatcaaaa gctgaccaag
    24541 ataaaatggg tgtggcttta caaaaactat ctgaagaaga tcctactttc cgtgctgaaa
    24601 caaatgtgga aacaggcgaa acaatcatcg ctggtatggg tgaacttcac ttagatatca
    24661 tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa cgtaggtgcg cctcaagtat
    24721 cttaccgtga aactttccgt gctggcactc aagccgaagg taagtttgta cgtcagtctg
    24781 gtggtaaagg tcaatacggt cacgtatgga ttgaatttac accaaatgaa gaaggtgctg
    24841 gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc tcgtgaatac attccagctg
    24901 ttgaaactgg tttgaaagat gctatggaaa atggtgtctt agctggctat ccattagtag
    24961 atatcaaagc taaactttac gatggttcat accatgatgt cgattcaaat gaaactgcct
    25021 tccgtgttgc tgcttctatg gcattacgtg cagcagctaa gaaagctaat ccagtaatcc
    25081 ttgaaccaat catggctgta gaagttgtta tccctgaaga ttatttaggt gatgttatgg
    25141 gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga agctcgcgct ggcggccaac
    25201 aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg ttatgctaca actcttcgtt
    25261 ctgctactca aggtcgtggt acatttacaa tgacatttga ccactacgaa gatgtaccaa
    25321 aatcagtaca agaagaaatc attaagaaaa acggcggaaa agctgaataa tttcttaaaa
    25381 ccggatagtc ctgcaaagag attatccaaa gagactatat ttttaatata gtttcgtgta
    25441 aaataattat cgatgatatg ggcatgtggt gtaccttgtg tacatcatat acctatcaga
    25501 caaataaaaa atatattgta tttttaggag gacattttaa aatggcaaaa gaaaaatttg
    25561 accgttctaa accacacgtt aacattggta ctatcggaca cgttgaccat ggtaaaacta
    25621 cattaacagc tgcaatcaca actgtactat ctaagaaaaa cggcggccaa gctatggctt
    25681 acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg aatcacaatc tcaacagctc
    25741 acgttgagta tgaaacagat acacgccact acgctcacgt tgactgccca ggacacgcgg
    25801 attacgttaa aaacatgatc actggtgctg ctcaaatgga cggagctatc ttggtagttt
    25861 ctgctgctga cggcccaatg cctcaaactc gtgaacacat cctattgtct cgtcaagttg
    25921 gtgttcctta catcgttgta ttcttgaaca aagtagacat ggttgatgac gaagaattac
    25981 tagaattagt tgaaatggaa gttcgtgacc tattaacaga atacgaattc cctggtgacg
    26041 atgttcctgt agttgctgga tcagctttga aagctctaga aggcgacgct tcatacgaag
    26101 aaaaaattct tgaattaatg gctgcagttg acgaatacat cccaactcca gaacgtgaca
    26161 acgacaaacc attcatgatg ccagttgaag acgtgttctc aattactgga cgtggtactg
    26221 ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg tgacgaagtt gaagttgttg
    26281 gtattgctga agaaacttca aaaacaacag ttactggtgt tgaaatgttc cgtaaattgt
    26341 tagactacgc tgaagctgga gacaacattg gtgctttact acgtggtgtt gcacgtgaag
    26401 acatccaacg tggacaagtt ttagctaaac caggtacaat cacacctcat acaaaattct
    26461 ctgcagaagt atacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcacta
    26521 actaccgtcc acaattctac ttccgtacaa ctgacgtaac aggtgttgtt gaattaccag
    26581 aaggaactga aatggttatg cctggcgaca acgtaacaat ggaagttgaa ttaatccacc
    26641 caatcgctat cgaaaacggt actaaattct caatccgtga aggcggacgt acagttggtg
    26701 ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt tttaaagtaa agcaacattt
    26761 attcggacgt aatcgctcgg aacgaaggtc ttaggatctt tgttccgagc ttttttattt
    26821 attgcaggat caggaaaaaa gacaggagta ttataaatag aagaaacacg aaa
//
LOCUS       DAIGUC010000042        26598 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.042, whole genome shotgun sequence.
ACCESSION   DAIGUC010000042 DAIGUC010000000
VERSION     DAIGUC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.042"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            99..542
                     /locus_tag="NOB46_001886"
     CDS             99..542
                     /locus_tag="NOB46_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI1058816.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="NOB46_001887"
     CDS             complement(548..1732)
                     /locus_tag="NOB46_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HCI1058817.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="NOB46_001888"
     CDS             2000..2698
                     /locus_tag="NOB46_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI1058818.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="NOB46_001889"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="NOB46_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCI1058819.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="NOB46_001890"
     CDS             complement(3508..4041)
                     /locus_tag="NOB46_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058820.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="NOB46_001891"
     CDS             complement(4338..6719)
                     /locus_tag="NOB46_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI1058821.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="NOB46_001892"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="NOB46_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HCI1058822.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="NOB46_001893"
     CDS             7420..7959
                     /locus_tag="NOB46_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HCI1058823.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="NOB46_001894"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="NOB46_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HCI1058824.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="NOB46_001895"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="NOB46_001895"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="NOB46_001896"
     CDS             9066..10232
                     /locus_tag="NOB46_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCI1058825.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="NOB46_001897"
     CDS             10278..11774
                     /locus_tag="NOB46_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HCI1058826.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="NOB46_001898"
     CDS             11855..12538
                     /locus_tag="NOB46_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1058827.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13183..14373
                     /locus_tag="NOB46_001899"
     CDS             13183..14373
                     /locus_tag="NOB46_001899"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCI1058828.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14475..15428
                     /locus_tag="NOB46_001900"
     CDS             14475..15428
                     /locus_tag="NOB46_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCI1058829.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15497..16846
                     /locus_tag="NOB46_001901"
     CDS             15497..16846
                     /locus_tag="NOB46_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1058830.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17029..17352)
                     /locus_tag="NOB46_001902"
     CDS             complement(17029..17352)
                     /locus_tag="NOB46_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058831.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17481..18644
                     /locus_tag="NOB46_001903"
     CDS             17481..18644
                     /locus_tag="NOB46_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI1058832.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18714..20063
                     /locus_tag="NOB46_001904"
     CDS             18714..20063
                     /locus_tag="NOB46_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI1058833.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20108..20539)
                     /locus_tag="NOB46_001905"
     CDS             complement(20108..20539)
                     /locus_tag="NOB46_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058834.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20927..23569
                     /gene="alaS"
                     /locus_tag="NOB46_001906"
     CDS             20927..23569
                     /gene="alaS"
                     /locus_tag="NOB46_001906"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCI1058835.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23769..24365
                     /locus_tag="NOB46_001907"
     CDS             23769..24365
                     /locus_tag="NOB46_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1058836.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24487..25635
                     /locus_tag="NOB46_001908"
     CDS             24487..25635
                     /locus_tag="NOB46_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI1058837.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25673..26086)
                     /locus_tag="NOB46_001909"
     CDS             complement(25673..26086)
                     /locus_tag="NOB46_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HCI1058838.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26165..26596
                     /locus_tag="NOB46_001910"
     CDS             26165..26596
                     /locus_tag="NOB46_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HCI1058839.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
BASE COUNT         8810 a         4607 c         5523 g         7658 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagttgc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg tcacagtcct
    12781 tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa ttaaaaattg
    12841 ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata aataaattaa
    12901 atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt gttgtattta
    12961 tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat actatataag
    13021 tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt ctcataatca
    13081 gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca cgatatatgt
    13141 ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc caaagaacta
    13201 acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata caatacgatc
    13261 gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa gatgatcaat
    13321 ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa agcatgtatt
    13381 gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa tggttcgctg
    13441 aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga agcagcaatc
    13501 gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat gacaaaagaa
    13561 gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg ccgcttatcc
    13621 ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa aaaagcaaag
    13681 gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg tgttttctcc
    13741 atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa atatggactg
    13801 atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc aggaaccgtc
    13861 aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc gaaagctata
    13921 ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt gaaagctaga
    13981 agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc tgcattggct
    14041 tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga aaatgctaat
    14101 tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga aacacctatt
    14161 actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa gctgatcgaa
    14221 catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac aggcaggatc
    14281 agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt agcagtttat
    14341 caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc gtctatttaa
    14401 aattagagaa catgttcacg catatattgt taatcatctg aagatagtag taaaaaagat
    14461 cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa attggttcag
    14521 agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg acagatatac
    14581 gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta atggattacg
    14641 aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat ttggctgctc
    14701 ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac gtgactgggc
    14761 tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg ccaagttcaa
    14821 tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact cttcagcgtc
    14881 ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat tattattatg
    14941 tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct tatgcaacct
    15001 tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca atcaaagaag
    15061 gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat atgccagatg
    15121 cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt catcgaaatg
    15181 ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct attcaaaaaa
    15241 tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca atagcagaat
    15301 cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt tcgccgaaat
    15361 acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa ttggtagaga
    15421 cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt ggctatggta
    15481 tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag taaaaataga
    15541 aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta tgggcacagt
    15601 gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag gatccgccag
    15661 tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag gactaacagg
    15721 agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata tcgaacggat
    15781 ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt attttccagc
    15841 aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat ttggtctttc
    15901 ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt tgatcaattt
    15961 tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca agcttattcc
    16021 tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact tccaactgtt
    16081 tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg gcttgctagc
    16141 aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag aattgaaaaa
    16201 gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca tgatcgttta
    16261 tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg caggaaacag
    16321 caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa gactggtcac
    16381 agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta ctggaatgcg
    16441 tctcccttat gttattgcaa aagaaaacaa cctgcctttt agcaagctct ttgctaaact
    16501 tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca tcgctattgg
    16561 catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg tcatttggat
    16621 tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac ctgatttgtt
    16681 tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca ttggagggac
    16741 ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg ggatagtatt
    16801 gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa aacattcgaa
    16861 ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga ggagtacgtg
    16921 gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt gtctacgatg
    16981 aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt actttgattt
    17041 gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca agcaaccaga
    17101 aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag acaaagcatg
    17161 tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat tgaagactag
    17221 catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag ttctttttct
    17281 tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa aaacaaagta
    17341 catattcagc atctcgacac cccctttgtg tttatcttac tttactttga aagaaatgag
    17401 aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa gagagataca
    17461 aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt gcgctgattg
    17521 tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa tatcgaaagt
    17581 atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt tatttattgt
    17641 gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc caaatgacag
    17701 ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac aacacggtat
    17761 tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta tttttggaac
    17821 cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat tatttccggc
    17881 tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt gaattgacgc
    17941 agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat gtgaatgatt
    18001 tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta tttacattta
    18061 tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag actgtctcat
    18121 tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt attaatttgg
    18181 tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct catatctggt
    18241 ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc aatggatgga
    18301 cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa cgaatttctt
    18361 taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt ttaagctggt
    18421 tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg cagatgagtg
    18481 cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta aatatcttgc
    18541 tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac acatatactg
    18601 ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc aaaaacgctt
    18661 tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca cgaatgaata
    18721 attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca aagggcttca
    18781 aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga aaaaatatca
    18841 ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct ttgtttgaaa
    18901 aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt agggaactag
    18961 ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg gagatccgtg
    19021 tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg catcaccaac
    19081 agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat gaacaagcgc
    19141 tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca ttggatatgg
    19201 gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg cagtttttag
    19261 ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac atggaaaatc
    19321 caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa aattggctga
    19381 tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca attggtcatc
    19441 cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt gccgattact
    19501 tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca agagagagaa
    19561 aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg actgatttag
    19621 ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa attccagaag
    19681 atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta aaaggaacgg
    19741 ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa aaattgggcg
    19801 tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac gatcgtaata
    19861 gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt ggtcttgtga
    19921 agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg gcaattgcag
    19981 aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact gctcgtaaaa
    20041 ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt gtcacaatct
    20101 cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct tcaataaaag
    20161 gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc atttcagcta
    20221 ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct tcaagcaact
    20281 gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc ggcttgaagc
    20341 aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga tcaagaaata
    20401 gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca ggaatccctt
    20461 gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc cattcatccg
    20521 ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat gtattgattc
    20581 ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga aaataaaaat
    20641 tgagatattg acagtgatca atagaatgcg tatactaatt aagtacgaaa aggatatgat
    20701 ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag tcactaatca
    20761 aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt atcgagttta
    20821 agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc gtccttggct
    20881 gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga aacaattaag
    20941 tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac atacgattga
    21001 acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca actctggtgt
    21061 tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa gaatcacaaa
    21121 tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag cacggcacca
    21181 tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa atgaagccat
    21241 ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc cagaaaaact
    21301 ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg aagaagttgg
    21361 cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg gtgcaggccc
    21421 atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg atttagcaga
    21481 agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa tctggaactt
    21541 agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc ctcataaaaa
    21601 cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg cgtcaacgaa
    21661 ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa gcaaacaagt
    21721 aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag atcatattcg
    21781 cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga gagggtatgt
    21841 cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta ttgaacaagc
    21901 attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt atcctgaagt
    21961 acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac gtttcaatga
    22021 aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa aaaacgaaaa
    22081 cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg gcttcccggt
    22141 agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg ctggttttga
    22201 aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg aaaaatcaat
    22261 gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca ttggatacac
    22321 agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc ttttgaatga
    22381 agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg cagaaatggg
    22441 tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg tagcagttgt
    22501 tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag taaaagcacc
    22561 aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca atcggatcat
    22621 caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac ttggcgagca
    22681 tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact ttacccactt
    22741 tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg aaaaaatctg
    22801 ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa acatgggtgc
    22861 aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata ttggcggctg
    22921 gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg gaatcttcaa
    22981 aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg taacaagtaa
    23041 agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag caacaattgt
    23101 taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac agcaagtaag
    23161 agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac aagctggtga
    23221 tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac aagtaaaagt
    23281 gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa atatttcaga
    23341 tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg caatgacgaa
    23401 agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg caccgaaagt
    23461 aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa atcctgctgg
    23521 tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg gcgtttacgt
    23581 ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg cgaagacaaa
    23641 caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat ggtcggattc
    23701 ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa ataaaaaggg
    23761 gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg atcttgttag
    23821 caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta ggattcatta
    23881 gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc ccaaaagatg
    23941 gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat gccatgccaa
    24001 caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt cccagagtac
    24061 ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat aaatcaataa
    24121 cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc ttagtgttag
    24181 gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta gactctgctc
    24241 ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa gcaataggtg
    24301 cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg ttgaaaccag
    24361 aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag gaagagagga
    24421 gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact agaaggggta
    24481 aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca gcggacaaaa
    24541 aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt tgtctctaag
    24601 ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt gaacagtcta
    24661 tcagatactg cttcatccat attgactttg atcggattta aaattgctgc aaagccagca
    24721 gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt atttgtttcg
    24781 atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa aatcatccat
    24841 ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc catctttttg
    24901 aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc tgaaacattg
    24961 agagctacag caacagatag ttataatgat gtctttacta cactggctgt attgctttca
    25021 gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt tgctttagca
    25081 ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga actattagga
    25141 agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc ttgcgatgat
    25201 atacttggct atcatgattt attggtgcat aactatggac ccaataaacg ctttgcatca
    25261 gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat tattgatctg
    25321 atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt ggatccaatg
    25381 cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat tcttcttgaa
    25441 acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa aacgctgcaa
    25501 tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga aagaatctta
    25561 cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt tgatcacaat
    25621 tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta atttaaagag
    25681 tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct gctcctttat
    25741 ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga agttcttgga
    25801 ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg accgtagaaa
    25861 ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg tttttcttta
    25921 gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc cctatagaaa
    25981 gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca cctccactag
    26041 gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa agagattctc
    26101 ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg tgagaggtta
    26161 gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca tctattggtc
    26221 attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca caggtcctta
    26281 ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag gtttgcggcg
    26341 ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt ggaaagaccg
    26401 agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg tgcaaatgat
    26461 gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc aagtagtcct
    26521 ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc cttatacgaa
    26581 aaaaagaaaa agctaatt
//
LOCUS       DAIGUC010000043        25502 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.043, whole genome shotgun sequence.
ACCESSION   DAIGUC010000043 DAIGUC010000000
VERSION     DAIGUC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.043"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            133..3660
                     /locus_tag="NOB46_001911"
     CDS             133..3660
                     /locus_tag="NOB46_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCI1058840.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="NOB46_001912"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="NOB46_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCI1058841.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQVIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="NOB46_001913"
     CDS             7448..7789
                     /locus_tag="NOB46_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1058842.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="NOB46_001914"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="NOB46_001914"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCI1058843.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="NOB46_001915"
     CDS             9146..11566
                     /locus_tag="NOB46_001915"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCI1058844.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB46_001916"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB46_001916"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCI1058845.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="NOB46_001917"
     CDS             13000..13737
                     /locus_tag="NOB46_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1058846.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="NOB46_001918"
     CDS             13751..14566
                     /locus_tag="NOB46_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI1058847.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="NOB46_001919"
     CDS             14579..15226
                     /locus_tag="NOB46_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1058848.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="NOB46_001920"
     CDS             15242..15898
                     /locus_tag="NOB46_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1058849.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="NOB46_001921"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="NOB46_001921"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCI1058850.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="NOB46_001922"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="NOB46_001922"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCI1058851.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="NOB46_001923"
     CDS             18240..18758
                     /locus_tag="NOB46_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI1058852.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="NOB46_001924"
     CDS             18865..19365
                     /locus_tag="NOB46_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1058853.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="NOB46_001925"
     CDS             complement(19645..20565)
                     /locus_tag="NOB46_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCI1058854.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="NOB46_001926"
     CDS             20730..21743
                     /locus_tag="NOB46_001926"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HCI1058855.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB46_001927"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB46_001927"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCI1058856.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB46_001928"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB46_001928"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI1058857.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="NOB46_001929"
     CDS             complement(23383..24144)
                     /locus_tag="NOB46_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1058858.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="NOB46_001930"
     CDS             24333..25427
                     /locus_tag="NOB46_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI1058859.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4423 c         5385 g         7247 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagtcatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtggacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 gg
//
LOCUS       DAIGUC010000044        24579 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.044, whole genome shotgun sequence.
ACCESSION   DAIGUC010000044 DAIGUC010000000
VERSION     DAIGUC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.044"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(153..551)
                     /locus_tag="NOB46_001931"
     CDS             complement(153..551)
                     /locus_tag="NOB46_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCI1058860.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="NOB46_001932"
     CDS             complement(548..1321)
                     /locus_tag="NOB46_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI1058861.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="NOB46_001933"
     CDS             complement(1318..2001)
                     /locus_tag="NOB46_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI1058862.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="NOB46_001934"
     CDS             complement(2168..3055)
                     /locus_tag="NOB46_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058863.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="NOB46_001935"
     CDS             complement(3052..3921)
                     /locus_tag="NOB46_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1058864.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="NOB46_001936"
     CDS             complement(4058..5344)
                     /locus_tag="NOB46_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1058865.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="NOB46_001937"
     CDS             5617..6195
                     /locus_tag="NOB46_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI1058866.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="NOB46_001938"
     CDS             6195..7124
                     /locus_tag="NOB46_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1058867.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="NOB46_001939"
     CDS             7121..8857
                     /locus_tag="NOB46_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI1058868.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="NOB46_001940"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="NOB46_001940"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCI1058869.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="NOB46_001941"
     CDS             complement(9753..10262)
                     /locus_tag="NOB46_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCI1058870.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="NOB46_001942"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="NOB46_001942"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCI1058871.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="NOB46_001943"
     CDS             complement(11563..12654)
                     /locus_tag="NOB46_001943"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCI1058872.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="NOB46_001944"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="NOB46_001944"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCI1058873.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="NOB46_001945"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="NOB46_001945"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCI1058874.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="NOB46_001946"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="NOB46_001946"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCI1058875.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="NOB46_001947"
     CDS             complement(16617..17591)
                     /locus_tag="NOB46_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HCI1058876.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="NOB46_001948"
     CDS             complement(17572..19455)
                     /locus_tag="NOB46_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HCI1058877.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="NOB46_001949"
     CDS             complement(19473..21698)
                     /locus_tag="NOB46_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI1058878.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="NOB46_001950"
     CDS             21813..22847
                     /locus_tag="NOB46_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1058879.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="NOB46_001951"
     CDS             complement(22914..23927)
                     /locus_tag="NOB46_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1058880.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="NOB46_001952"
     CDS             complement(24005..24193)
                     /locus_tag="NOB46_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCI1058881.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7065 a         5342 c         4397 g         7775 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atacaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg ctgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctctct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cgcaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaactc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DAIGUC010000045        24271 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.045, whole genome shotgun sequence.
ACCESSION   DAIGUC010000045 DAIGUC010000000
VERSION     DAIGUC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.045"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..572
                     /locus_tag="NOB46_001953"
     CDS             <1..572
                     /locus_tag="NOB46_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1058882.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="NOB46_001954"
     CDS             576..1217
                     /locus_tag="NOB46_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058883.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="NOB46_001955"
     CDS             1214..2131
                     /locus_tag="NOB46_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1058884.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="NOB46_001956"
     CDS             2128..2799
                     /locus_tag="NOB46_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058885.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="NOB46_001957"
     CDS             complement(3340..3828)
                     /locus_tag="NOB46_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HCI1058886.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="NOB46_001958"
     CDS             complement(4029..4295)
                     /locus_tag="NOB46_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI1058887.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="NOB46_001959"
     CDS             complement(4295..4558)
                     /locus_tag="NOB46_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1058888.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="NOB46_001960"
     CDS             5034..5219
                     /locus_tag="NOB46_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1058889.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="NOB46_001961"
     CDS             complement(5361..7184)
                     /locus_tag="NOB46_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCI1058890.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="NOB46_001962"
     CDS             complement(7782..10487)
                     /locus_tag="NOB46_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCI1058891.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="NOB46_001963"
     CDS             complement(10793..11740)
                     /locus_tag="NOB46_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCI1058892.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="NOB46_001964"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="NOB46_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI1058893.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="NOB46_001965"
     CDS             complement(12375..12737)
                     /locus_tag="NOB46_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1058894.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="NOB46_001966"
     CDS             complement(12748..13869)
                     /locus_tag="NOB46_001966"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCI1058895.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="NOB46_001967"
     CDS             complement(13885..14235)
                     /locus_tag="NOB46_001967"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCI1058896.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="NOB46_001968"
     CDS             complement(14365..15876)
                     /locus_tag="NOB46_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI1058897.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="NOB46_001969"
     CDS             complement(16198..17550)
                     /locus_tag="NOB46_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCI1058898.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="NOB46_001970"
     CDS             complement(17703..18779)
                     /locus_tag="NOB46_001970"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCI1058899.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="NOB46_001971"
     CDS             18975..20720
                     /locus_tag="NOB46_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCI1058900.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="NOB46_001972"
     CDS             complement(21000..21437)
                     /locus_tag="NOB46_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCI1058901.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="NOB46_001973"
     CDS             complement(21421..22794)
                     /locus_tag="NOB46_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058902.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAICLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="NOB46_001974"
     CDS             complement(23116..23604)
                     /locus_tag="NOB46_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1058903.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="NOB46_001975"
     CDS             complement(23626..24228)
                     /locus_tag="NOB46_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI1058904.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6959 a         5162 c         4489 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaataggc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DAIGUC010000046        23825 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.046, whole genome shotgun sequence.
ACCESSION   DAIGUC010000046 DAIGUC010000000
VERSION     DAIGUC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.046"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(53..787)
                     /locus_tag="NOB46_001976"
     CDS             complement(53..787)
                     /locus_tag="NOB46_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI1058905.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="NOB46_001977"
     CDS             1114..1524
                     /locus_tag="NOB46_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCI1058906.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="NOB46_001978"
     CDS             1517..2218
                     /locus_tag="NOB46_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCI1058907.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="NOB46_001979"
     CDS             2218..3804
                     /locus_tag="NOB46_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1058908.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="NOB46_001980"
     CDS             3823..4044
                     /locus_tag="NOB46_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HCI1058909.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="NOB46_001981"
     CDS             4041..4802
                     /locus_tag="NOB46_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HCI1058910.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="NOB46_001982"
     CDS             5182..5691
                     /locus_tag="NOB46_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI1058911.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="NOB46_001983"
     CDS             complement(5766..6305)
                     /locus_tag="NOB46_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCI1058912.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB46_001984"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB46_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCI1058913.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="NOB46_001985"
     CDS             7318..8169
                     /locus_tag="NOB46_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCI1058914.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="NOB46_001986"
     CDS             8197..8832
                     /locus_tag="NOB46_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCI1058915.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="NOB46_001987"
     CDS             8852..9625
                     /locus_tag="NOB46_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1058916.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="NOB46_001988"
     CDS             10033..10830
                     /locus_tag="NOB46_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HCI1058917.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="NOB46_001989"
     CDS             10808..11221
                     /locus_tag="NOB46_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI1058918.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13847
                     /gene="mutS"
                     /locus_tag="NOB46_001990"
     CDS             11205..13847
                     /gene="mutS"
                     /locus_tag="NOB46_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI1058919.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAQGYIDALIEKGYKVAICEQVEDPKTTKGMV
                     KREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDEE
                     AVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVDP
                     LEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKKH
                     GTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSALT
                     KVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPMD
                     HLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQETG
                     IKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILEA
                     EEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELVS
                     DKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLALT
                     VLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPNS
                     LILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNVH
                     VGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGHH
                     TVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIESL
                     KQINLLEMTPMDALNTLYELQKQL"
     gene            13865..15973
                     /gene="mutL"
                     /locus_tag="NOB46_001991"
     CDS             13865..15973
                     /gene="mutL"
                     /locus_tag="NOB46_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCI1058920.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15995..16555
                     /gene="maf"
                     /locus_tag="NOB46_001992"
     CDS             15995..16555
                     /gene="maf"
                     /locus_tag="NOB46_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCI1058921.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16640..18628)
                     /gene="treP"
                     /locus_tag="NOB46_001993"
     CDS             complement(16640..18628)
                     /gene="treP"
                     /locus_tag="NOB46_001993"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HCI1058922.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18851..19564
                     /gene="treR"
                     /locus_tag="NOB46_001994"
     CDS             18851..19564
                     /gene="treR"
                     /locus_tag="NOB46_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HCI1058923.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19641..20087
                     /gene="msrB"
                     /locus_tag="NOB46_001995"
     CDS             19641..20087
                     /gene="msrB"
                     /locus_tag="NOB46_001995"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCI1058924.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20257..20859
                     /gene="ruvA"
                     /locus_tag="NOB46_001996"
     CDS             20257..20859
                     /gene="ruvA"
                     /locus_tag="NOB46_001996"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCI1058925.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20872..21873
                     /gene="ruvB"
                     /locus_tag="NOB46_001997"
     CDS             20872..21873
                     /gene="ruvB"
                     /locus_tag="NOB46_001997"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCI1058926.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21902..22480
                     /locus_tag="NOB46_001998"
     CDS             21902..22480
                     /locus_tag="NOB46_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1058927.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22532..23014
                     /locus_tag="NOB46_001999"
     CDS             22532..23014
                     /locus_tag="NOB46_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HCI1058928.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23131..23505
                     /locus_tag="NOB46_002000"
     CDS             23131..23505
                     /locus_tag="NOB46_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058929.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4284 c         5114 g         6647 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca caaggatata tcgatgcctt gattgaaaaa ggctataaag
    11461 tagcgatttg cgagcaggta gaagatccaa agacgactaa agggatggtc aagcgcgaag
    11521 tgatccagct agtcactcct ggtacagtca tggacagcaa aggattgtcg gcaaaagaca
    11581 acaatttttt aacagctgta gttagtcaag gaaatgaatt tggctttgct tatgccgatt
    11641 taagtacggg agaattgaag acggctcggt tgcatgatga agaagctgtt ttaaatgaag
    11701 cctctgcatt gcagacaaaa gaactcgtat taggcagtga gatcactgat acccttcgtg
    11761 aacagctaag cgggcgttta gggctagtct tttctcaaca aaatgagatg gaagaaaacg
    11821 cggaatttag ctttttgaca agcgaactag tcgatccgct ggaaaaagaa gcaaccggca
    11881 aactattgac ttatttatcg gtgacacaaa agcggagttt agctcatatc caaaaagcag
    11941 tagaatacca accagatcat tttttgaaaa tggattatta ttcaaaattc aacctagaat
    12001 taagccaatc tattcggact gggaaaaagc acggcactct tctatggttg ttagatgaaa
    12061 caaaaacagc aatgggtggc cgtttactaa aacaatggct agaccgtccg cttatccagg
    12121 caaaacaaat taaagcaaga caagaaatgg tcgcttcttt gctagacagc tattttgaac
    12181 gtatcgattt gcagtcagca ttaacgaaag tctatgatct ggaacgccta gcaggtcgag
    12241 tagctttcgg taatgtcaat gggcgagact tgatccagct gaaaacttct ttagaacaag
    12301 tgccaatgat cagagggttg attgaaggaa tcgatcaagg tcaatggcaa agtctgcttt
    12361 cagaaatgca gccgatggac catctcgtcc aattgatcga ccaagctatc caagatgatc
    12421 cgccgttaca aataacggaa ggaaacatca tcaaagatgg attcaatgag cagctcgata
    12481 tgtaccgttc tgctatgaga aacggaaaga aatggttggc agaacttgaa gcaaaagagc
    12541 gtcaagaaac aggaatcaag aacttaaaaa tcggatttaa ccgcgttttc ggttattata
    12601 tagaaattac aaaagcaaat cttggaaatg cagaactgga gaagtatgaa cgaaaacaaa
    12661 ctttagcaaa tgcagagcgt ttcatcacac cagaactaaa agaattggag acacaaatcc
    12721 tcgaagcaga agaaaaatct gttgatttag aatatcagtt gtttttagct gtgagagaag
    12781 aagtcaaaaa ggctatccag ccgctacaag tacttgcaaa agcaatcagt gcagtagatg
    12841 tgctacaaag ttttgcaacg atcagcgaac gctatcagta tgttcggcca gaacttgtca
    12901 gtgacaagca tcagcttctg atcaaagacg gacgacatcc tgtagtagaa aaagtattag
    12961 gacatcagga atatatccct aacagcgtag aaatggcaga agacgaaatg atcttgctga
    13021 ttacaggacc gaatatgtct ggtaaaagta cgtatatgcg acagttggca ttaactgttc
    13081 tgatggcgca aatgggctgt ttcgttccgg caaaacaagc agttttacct atttttgatc
    13141 ggatttttac ccgaattggt gcaagtgacg acttaattgc tggacaaagt acttttatgg
    13201 tagagatgat ggaagccaat caagccctgc gttatgctac gccaaacagt ttgattttgt
    13261 ttgacgaact agggcgagga acagcaacct atgacggaat ggcgttggcc caagcaatca
    13321 tcgaatatat ccatcgtcat gtacaagcaa aaacactctt ttctactcat tatcatgaac
    13381 tgacggtact tgagaaagaa cttccgcagc ttaaaaatgt ccatgttgga gccgttgaaa
    13441 aagacggaga agttgtcttc ttgcataaaa tgatggatgg acctgcggat aaaagctacg
    13501 gcatacatgt ggcaaagatc gcaggattgc cttccaatct actagaacga gcagcagata
    13561 tcctgcatac gctagaaaat ggcgataacg gacaccatac tgttccagct gaagtagaag
    13621 agaaaactaa aacagccaaa caggagcaaa taaaaccacc tgcagaaaaa gtaaatcaag
    13681 accatataca agaccgtgta aaagaagaaa accaacagct ttctttattc agtgaattat
    13741 ccgaaaatga aacagaagtc attgaatcac tgaagcaaat aaatttacta gaaatgacgc
    13801 caatggatgc actaaacaca ttatatgaat tacaaaaaca actgtaggaa gaaggcggat
    13861 atcgatggcc aaaatccaag aattatctga acgtttagct aatcagatcg ctgcgggaga
    13921 agtagtggag cgaccagctt ccgttgtgaa agaattagtg gaaaatgcaa ttgacgccgg
    13981 cagtactcag attgatatct tagttgaaga agcgggactg cggacgatcc aagtgattga
    14041 taacggagaa ggcattttgg cagacgacgt agagaatgcc ttcaagcggc atgcgacaag
    14101 taagatccat aatcgcgacg atctttttcg catacgaacg ctgggctttc gaggggaagc
    14161 tttgccaagt attgcctctg tttctgaaat gactctggaa acggcgaatc aggaagaaaa
    14221 acaaggcacc tatctgtcgc tgaaaggcgg agaagttatt gagcatcgac cagcaccact
    14281 gcgtcaagga acgaagatta ccgtcagcaa tctgtttttc aatacgccag cccgcttgaa
    14341 atacgtgaaa acactgcaca cagaattagc gaacatcggg gacatcgtca atcgactggc
    14401 attgagtcat ccatcgattg cttttcgttt agtacatgat ggaaacaaaa tgctggcaac
    14461 tgctggaaat ggcgatctga aacaaacaat tgcgggaatc tacggattat ctaccgcaaa
    14521 aaaaatgctg aaaatcgaag gaaaagatct agattttgag ttatttggct atgtttcatt
    14581 gcctgaggtg actcgtgcca gtaggaatta cttatcgacg atcatcaatg gacgttttat
    14641 caagaacttt tccttgaata aagcaatcgt tgcaggttat gggtcaaaat taatggtcgg
    14701 tcgtttccct attgctgtat tggaaatcaa aatggacccg cttttagtag atgtaaatgt
    14761 tcatccgacg aagcaggaag tccggctgtc gaaggaaaaa gaactaacag agctaattag
    14821 taacgccatt caaaaagcat tgtctcaaga aaatctgatt ccaagtgcag cggataatct
    14881 acggtttaag aaaaaagtac ctgatcagcc taaaacagaa caaatcgaaa tcgatttgtc
    14941 ctacgctttt gaagaagaaa aacctaaaaa gccaagtagt ttgaattttg atcgagagac
    15001 aggtaccttt ttcgtagaag aactaaagaa cacatttgtt gacagaattg ttgataagtc
    15061 tgtggaaaat gttgaaaact attctggttt ttctgaagaa aacaccactt atccagaaaa
    15121 aacagcgaaa acggtggata agtttggtga aaatgttgat aactttgtag aaaaaacagt
    15181 ggaaaaatct gaaaagaaag aatttcccat tgtggataac atggagaaaa caaatgaaga
    15241 acaagcagat aaatccgtag aagaggatga aaagatttac gaggaagaat tgacactcca
    15301 tcctgaattt gatttcactc aaggaaacga caaaacatta gaacaagcca tcaagaaatt
    15361 agaaacggaa aaaccagtac aacgttttcc tcagttggaa tattttggac agatgcacgg
    15421 aacgtatctt tttgcccaaa gtagcgatgg gttgtacatc attgatcagc atgctgccca
    15481 agagcgcatt aagtatgaat atttccggga aaaaattggg gaagtatctg atgatctgca
    15541 agaattgctt gttccatttg tgttagacta tccaaacagt gatgctttga aattaaaaga
    15601 gcaaaaacac ttgctagaag atgcagggat ttatttagaa gaatttggtc aaaacagctt
    15661 tattgtacgg gcccatccta cttggtatcc caatggagaa gaagaatcga ttattcggga
    15721 gatgatcgat atgctgctga caactggaag tgtgagtgta aaaaaattcc gtgaagcaac
    15781 agcaatcatg atgagttgca aacgatcgat taaagccaac cattatttga atgaagcaca
    15841 agcacgtgtg ctgctgaagg atctggcacg atgcgaaaat cctttcaatt gtccccatgg
    15901 ccgtccagta ttgattcact ttaccaattc ggatatggaa aggatgttca aacgaatcca
    15961 agacccgcat taagtcaaag agaagaggga aaacatgaag attgtattag catcccaatc
    16021 accaagaaga aaagagttat tggctcatat cgtttcagaa ttcgagattg aacctgctga
    16081 tatcgatgaa acgccatttc cagacgaaca gcccgtcgat tatgttcgta gaatggctga
    16141 agaaaaagca cgaactgtct gggaacaaga tgaaaaagaa gaccatttag tgattgccag
    16201 tgacacgact gttgttctca atcaagagat catgggtaaa ccagaagatc tggctgaggc
    16261 tgaattcatg ctgaaaaaac taagcgggga aacacatact gtatatacag ctgttgtttt
    16321 aaaaacaaag gaacgagaag aacggatact agcagaagca catgtcactt tttatccttt
    16381 gacagacgaa gagatcaaac gctacttgga gacgggggat tatgcggata aggcaggggc
    16441 atacggcatc caaaatgctg cgagtgtatt cgtcaaagaa atttctggag attattacag
    16501 tatcgtagga tttccgattg gtgctgtcaa tcaggcactg aaaacattca tttaaacaaa
    16561 aaagcggact atctgatttt cgattgaaaa tccatgatag cccgtttttt ttattgaaaa
    16621 gattacttat ctactctgac taagatttta cttcagcttt accgactgct tcgcccgggc
    16681 gaacaagtcc tgattggtca agagaaagtc ctgcaacttt ttcattattg gtcaaagcaa
    16741 caataatgtc agttttcttg ccagcttgtt ctatttctgg caaatccatt tcagcaatca
    16801 gggtctctgg tgtgacaagg tatccttctt tcacgaatac attgaaagga acacccttta
    16861 gttcaacagt atctaatccc atgtgaacaa gtacttccag cccctcatta gaaagaatac
    16921 caatggcatg ttttgtttca aagacactcg tcactttacc gtttactggt gcatagactt
    16981 tgccgtttga cggttcgaca gcataaccgt cacccatcat tttttgtgag aaaactgggt
    17041 catttacttc agttatttcc ttgatggtcc ctgcagcgac tgcgaataat gtttcttttg
    17101 ttgcaactgc cgtaccagtt gctgaaacag gttcgaaaga ctgtggcgtt gctgttgcgc
    17161 catttgctgt ttgaagttgt acatcagcag cattttcagg aacagcagga tcaatcttat
    17221 tcaaaattcc ctgacgtcta aagatgatcg tcaagccaaa tggaatgatg acagcaatga
    17281 tcattgcgat gatgaaaggt acccatgttt ctgcttggat agctagtatt cctggcaaac
    17341 cgcctactcc gatcgcgtta gctcgaacac ccatcaagtt agcaaacatg ccagctaatc
    17401 cagagccgac cattgcagcg acgaaaggat agacgtattt caaattgatt ccgaacatag
    17461 caggttcagt tacgcctaag taacaagaaa tcattgctgg aatcgagatt tgttcttctt
    17521 ttttattccc acgatgtaag aagatgatgg ctaagactgc agagccttgg gcgatatttg
    17581 ataaagcaat catcggccat aaattcgttg atccgaaatc tgcaatcagc tgcatatcga
    17641 tggcattggt catatggtgg agaccagtaa tcactaaagg agcatacagg aatccgaata
    17701 cggcactaaa caaccagctg atagaagacg tcaatccagt atttacgata tttgagatcc
    17761 agcttccgac tgtccagccg ataggaccta aaataacgtg tgcagctaaa acagttggta
    17821 acaatgaaaa caatggaaca aaaatcatcg agatcgactg agggatatat ttgcggaaga
    17881 agatttctag atacgctaac ataaaccctg ccagcatggc tggaataact tgcgcttgat
    17941 aaccaatcat ctggacttga gcaaaaccaa aatcccaaaa tggaatatct gctgcggctg
    18001 tggaagctac actataagca tttaataatt gcggagaaac taacgtaatt cctaaaacga
    18061 ttcctaatat ttgtgtagta cccatctttt ttgcaatact ccaagtgata cctactggaa
    18121 gaaaatggaa aattgcttca cccggtaacc acaaaaaggc attgacacca ttccaaaact
    18181 tcgagtgttc aacgattgtt ccaccaagac tttcaaactg gataccttca agtacatttc
    18241 tgaatccaag gatcaatcca ccgacaatga ttgcaggaat cagtggtgta aagatttctg
    18301 ctaaaacggc aatagcacgt tgaacgggat gaaggttttg ttttgcagct gcttttcctt
    18361 gttctttgga aaccccttca actccagata ctgcaacgaa gtcgttataa aaagtagaaa
    18421 catcgtttcc tatgatgact tggaactgtc ctgcattcgt gaacatccct tttacgctag
    18481 gtatatcttc gatcgctttt tcgtccgctt ttcctggatc attcaggaca aaacgcatac
    18541 gagtcgcaca atgactaact gcagcaatat tttcttttcc gccgatatca tgtaacagct
    18601 tctcggcatc tgcttgatat tttgccatat caataaaccc ctttctctta acttgtctat
    18661 gcaagttgtt tcttcattta ctatactttt tttcggagag aattgcaagc gttttattaa
    18721 aaagtacgag agaaaatgat atcgttttaa aaagcttaaa ataagctttt cttaaaaata
    18781 ggaacattga aatacaaaaa gagctgtagt atagtgaaga aatgatggaa gaacgagtga
    18841 gggaaaaaac atgaataagt tcaatgaaat ttttttagat ttggaacaga aaattttagc
    18901 gaaagaatat cctccgcatt cgcttttacc cagtgagaac caattgatca aaatttatgg
    18961 tgtttcacga gaaacaatta gaaaagcgct gaatcttttg actacggaag gttatattca
    19021 aaaaaaacaa ggaaaaggtt cgatcgtact ggatcggaat cgcttcgact ttcctatttc
    19081 tggattgact agctataaag agctacagga gacccaacgt attccaagtg aaacgatcat
    19141 ccatacgtta gaagaaacag aagtgacaaa agcattgaac gagatcactg gctgggagat
    19201 cggtgcgcct gtttggcatt tgatacgcga aagaaaaatc aatggcgaag tagttatatt
    19261 agacaccgat tatctattaa aggaaatcgt tcctatttta actccagcac aagcacaagg
    19321 atcgatctat gaatattttg aaaatgagct ttctttgacg attgcttacg cgcaaaagga
    19381 gatcacagta gaagaagtaa cggaaatcat gaaaacagcg atggatcttc acgatgacac
    19441 ttatgcagta gtagtcagaa gcctcgttca tctggaagat acccgctgtt tcgagtattc
    19501 tgagtcggtt caccgattag ataaattccg tttcgttgag tttgcccgac gccgaaaagt
    19561 gtaaatagtt caaaagaaag caaattgttg gcatctgtcc actttggcgc tatgatagga
    19621 tcacaaaggg ggcattttta atggataaac caataagacc agaaaaagaa gaactgaaag
    19681 aaaagttatc acccatggct tatgcagtca cacaagaaaa tgcaacagaa cgaccattta
    19741 gcgggaaata tgatgatttt tacgaaaagg ggatctatgt agatatcgtc agcggtgaac
    19801 cgttattcag ctctgcagaa aaatatgatg caggttgtgg ctggccatca ttcagcaaac
    19861 caataacgaa aagacaagtg cgcgaaaaag ccgatttttc tcatggcatg catcgaatag
    19921 aagttcgaag caaagaagca gattctcatc tcggacatgt gtttaccgat ggaccagtag
    19981 atcaaggtgg tctacgttac tgcatcaatt ctgcctcact gaaattcatt ccatatgaaa
    20041 agatggatga attaggttat ggggaattca aatcacttgt agaataatgg aaatacacaa
    20101 agagcggtac aatacgggga tttactcgat cgtccgctct ttttttattc aagcgattgc
    20161 tatttgaaag aaacgctccc tagactcctt ttttcacaag gtgaaatgtg ctacaataaa
    20221 gggaacgtat gtgtgcaaaa gaaagaggac tagaatatgt atgaatatct gacaggtgtg
    20281 gttaccttta tcaaccccta ttacatagta gtagaaacca atggtatcgg ctaccagatc
    20341 gcactaggaa atccttaccg ctacagtagc aaactaaatc aaaaaataaa aatttatgtc
    20401 catcaggtaa tacgtgaaga tgcgcatctt ctgtatggat ttgattcgct agaagaaaag
    20461 caactgtttt tgcgattagt aagtgtttca ggaatcggtc cgaaaagtgc ccttgcaatc
    20521 atggcaagcg aagaccactc cggtttgatt caagcagtag aatccagtga tgtcacttat
    20581 ttgacgaaat ttccaggagt agggaaaaag acagcacaac aaatgatctt ggatctaaaa
    20641 ggaaaattcg gtgagctgag tatcgataca ccttttagtc tatttgatga agcaaacaca
    20701 aaagacgcta cagctctatc tgaagcaatg gaagctctct cggctcttgg ttacagtgat
    20761 cgagaaatca aacgtgtaga aaaacaatta aaagaagtag ataatcagac aacggatgag
    20821 tatctacgcc aagcactcaa gctaatgatg aaaaaataag gaggagacca aatgacagat
    20881 gaatacttgt tatcaccaga atctggcgaa aatgaactga gtttggaaaa atctcttcga
    20941 ccacagctgc tttctcaata tatcggacag agaaaagtca aacaagaact tcagatttac
    21001 atcgaagctg ccagaaatcg ggaagaacct ttagatcatg ttctgttgta cgggcctcct
    21061 ggattaggaa aaacgacgat ggccatggtc attgctaatg agatgaccgt aaatattcgt
    21121 acgacgagtg gccctgctat cgaacgtccg ggtgacttag tagcaatctt gaatgaactg
    21181 gaagcagggg atgtcctgtt tatcgatgag atccatcgat tacctagagt ggtagaagag
    21241 atgctttatt cagctatgga agatttctat gtagatatca tggtaggaca agggccaacc
    21301 gcacatccgg ttcatttccc tcttcctccc tttactttga ttggcgcgac gacacgggca
    21361 ggtatgcttt ctgcaccttt acgagatcga tttggcatca tttctcatat ggaatattat
    21421 gacgaacagg atctgcagga gatcgtttta cgttcttcgg atatttttca aacagagatc
    21481 attgaagaag gggcattgga aattgctcgc cgatcacgag gaacgcctag aatcgctaat
    21541 cgcttgctca aacgggttcg tgattttgcg caagtccaag gagacgggaa aatcgatcgt
    21601 cctatagcgg atcaggcact tactttgcta caggtcgatc aggctggatt ggattatgtt
    21661 gaccagaaat tgttgcgaac aatgatcgag ttatatggcg gcggaccagt agggttaagt
    21721 acgctttcag taaacatagg agaagagcgt gagacggtag aagatatgta tgaaccgtat
    21781 ctgatccaaa aaggattttt aaagcgtaca cctagagggc gaattgctac tgcttatgcc
    21841 tatgaacatt ttggttacga ctatcatata tgatttttgc ttttagattg gaggaaaatg
    21901 aatgagtgat acaacacgta cgaaacaatt gatcaaaaac gtattgattg atttgtgcca
    21961 aacgcaatct tttcgaaaaa tcagcgtcca aaaaatcgca aacgaagcaa aaatcaatcg
    22021 acaaacattt tattatcatt ttacagataa atacgatttg cttcgttggg tctattgtga
    22081 ggatgcattg cattatttag atccacaatg tctttcactt gataattggg aagagcaagc
    22141 attgaaaatg ctgaaagcaa ttgctgagaa gaaagaattt tatgcaaata ctgtgctttc
    22201 tgacccagaa attttacaaa aagagttttc tcaactgatc caaaaatcat ttatcaagat
    22261 ttttgaacaa atggatgaag aaagacaact ttctgcaaga gacaaactat tttatgctcg
    22321 ttttttttct tacggttgca gtggtgtatt agtcaattgg atcacgaatg aatatgaaga
    22381 aacaccgatg gaaatcgcta tgcagctttt ccgtttagcc aaggatacgg aattatattc
    22441 ttatcgtctt tatgcaaaag aagagttgga agaacagtaa tagaaaaatt ttttgttgga
    22501 aaagcaataa tcgctaaaag gagatgggga aatgacaaaa attttatttg tttgtttggg
    22561 aaatatttgc cgttcaccga tggcagaagg cttgctgaga aaacgaatag cattagaagg
    22621 aagggaagca gaattttttg tggattctgc tgctacaagc acgtatgaag ttggaaagac
    22681 accgcaccct ggaacgaaaa aaatattaaa ccaagaaaaa gtagatatga cgaatatggt
    22741 tgctcggcaa atcacacccc acgattttga aacttttgat tggatcattg gcatggatca
    22801 agaaaatgta gaagaactga aacgaagagc accacgctca gcgcagggga aaatccattt
    22861 gtttttaagt agcattcctg gaaaagaaaa agaaaatgtt cccgacccat actataccaa
    22921 taactttgat gagacatatc acttgatcac agaaggcctg aatcattggt ggaatatttg
    22981 gattgatgaa aataaaataa caaataattt gtaaagttaa cgctttcttt ttaaggcgat
    23041 gttagagcat ttccttgttt ttttgtaaaa tgttaggtaa aataaaatta attaagtaac
    23101 actttcttag ctaaaggagg agtgcattcg atgaacgaag agacagtatc gccaatgaag
    23161 aagcttacga agttagttac tcatacttcg tatcaacttt ttgattcttt tgtaaatgac
    23221 actgaagaac atgctaagaa tgtacgattg caaggaaagt ttattcttga gctgcaaaaa
    23281 gctgctactg aacatagtct agttatctta caagtaagag caaatcgttt gagtagcaag
    23341 tatgaaacga tctcaggctg ggtggcgaca aaaacggtcg aaaaagaccg agtgatgatc
    23401 cgcctacaaa acgaagagca gcagatccgg atggttcctg tagaacaaat tgaaaaaata
    23461 acaatccttt caccagcagg ggaacaggaa cggttatcaa aataatttat accagataga
    23521 aaagcacgta tgagcttgta ccatcaatca ttactaatca aaaataaccg aatgctttaa
    23581 gctgatatca gtaaaacgga acgttttagg atgagtatca tagcatgaca gcattcggtt
    23641 gattagttga atcgattgga tggtacaagt ttttttgata aaaaaaggtc ctgctagccg
    23701 gggagctagc aggataagga gttaaaaatg aaaaagtgtt gttagggttg tttgttggta
    23761 tgcttatata atagtcatta gttgtgaata ttttgtgacg aaagttttcg aaagttgtta
    23821 agttt
//
LOCUS       DAIGUC010000047        23462 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.047, whole genome shotgun sequence.
ACCESSION   DAIGUC010000047 DAIGUC010000000
VERSION     DAIGUC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.047"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            291..698
                     /locus_tag="NOB46_002001"
     CDS             291..698
                     /locus_tag="NOB46_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058930.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            712..1113
                     /locus_tag="NOB46_002002"
     CDS             712..1113
                     /locus_tag="NOB46_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058931.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1115..1486
                     /locus_tag="NOB46_002003"
     CDS             1115..1486
                     /locus_tag="NOB46_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058932.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1859..2059)
                     /locus_tag="NOB46_002004"
     CDS             complement(1859..2059)
                     /locus_tag="NOB46_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1058933.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2364..3596)
                     /locus_tag="NOB46_002005"
     CDS             complement(2364..3596)
                     /locus_tag="NOB46_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCI1058934.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            3850..4419
                     /locus_tag="NOB46_002006"
     CDS             3850..4419
                     /locus_tag="NOB46_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1058935.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4597..5037)
                     /locus_tag="NOB46_002007"
     CDS             complement(4597..5037)
                     /locus_tag="NOB46_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCI1058936.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5195..5959
                     /gene="map"
                     /locus_tag="NOB46_002008"
     CDS             5195..5959
                     /gene="map"
                     /locus_tag="NOB46_002008"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCI1058937.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            5991..6914
                     /locus_tag="NOB46_002009"
     CDS             5991..6914
                     /locus_tag="NOB46_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCI1058938.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            6990..8129
                     /locus_tag="NOB46_002010"
     CDS             6990..8129
                     /locus_tag="NOB46_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HCI1058939.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8122..8922
                     /locus_tag="NOB46_002011"
     CDS             8122..8922
                     /locus_tag="NOB46_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1058940.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            8922..9749
                     /locus_tag="NOB46_002012"
     CDS             8922..9749
                     /locus_tag="NOB46_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1058941.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9727..10461
                     /locus_tag="NOB46_002013"
     CDS             9727..10461
                     /locus_tag="NOB46_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1058942.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10561..11427
                     /gene="rfbA"
                     /locus_tag="NOB46_002014"
     CDS             10561..11427
                     /gene="rfbA"
                     /locus_tag="NOB46_002014"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCI1058943.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11441..12013
                     /gene="rfbC"
                     /locus_tag="NOB46_002015"
     CDS             11441..12013
                     /gene="rfbC"
                     /locus_tag="NOB46_002015"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCI1058944.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12035..13063
                     /gene="rfbB"
                     /locus_tag="NOB46_002016"
     CDS             12035..13063
                     /gene="rfbB"
                     /locus_tag="NOB46_002016"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCI1058945.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13161..14012
                     /gene="rfbD"
                     /locus_tag="NOB46_002017"
     CDS             13161..14012
                     /gene="rfbD"
                     /locus_tag="NOB46_002017"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCI1058946.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14047..16080
                     /locus_tag="NOB46_002018"
     CDS             14047..16080
                     /locus_tag="NOB46_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058947.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16124..17404
                     /locus_tag="NOB46_002019"
     CDS             16124..17404
                     /locus_tag="NOB46_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HCI1058948.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17614..18420
                     /locus_tag="NOB46_002020"
     CDS             17614..18420
                     /locus_tag="NOB46_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1058949.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18432..19652
                     /locus_tag="NOB46_002021"
     CDS             18432..19652
                     /locus_tag="NOB46_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1058950.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19642..21228
                     /locus_tag="NOB46_002022"
     CDS             19642..21228
                     /locus_tag="NOB46_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1058951.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21267..23405
                     /locus_tag="NOB46_002023"
     CDS             21267..23405
                     /locus_tag="NOB46_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1058952.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALKMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7491 a         3909 c         4818 g         7244 t
ORIGIN      
        1 tttttgaggg gaagtacata tagttgttga tatagttgct aatattgtta gctaatttgt
       61 tagtaaaact gtatacgaat ttagatagta aaaaaacagt ttgttcctta tatagaggca
      121 cttttactac tgattaaatg tcagatatgc ttacaaatat acttataaat atgcttacaa
      181 aattagctaa tatttccgtt gacaaagctt tgttactatt gttaaactaa attgactagc
      241 aaaagtgaaa cataaattta ttaaataaat gtaaaaatta ggagaaatca atgtcttata
      301 gagtacaatt aataatttca gaagatgtag aaagtcagca atttggcact aatgttatta
      361 ataaagtaat taatccagct ctttctatta atgcgccttt aattcctact gctttatcat
      421 tttctgtaac agctgtggtg tctgagatag aggatacaga aaagataaaa atagtagaaa
      481 ttgaagtttt aaacaagaat gaaaaacaaa ttttttctac gggtgaagta tcggtaagct
      541 tgcctcctca agttaacgat ataaacttta atataaacgc cagaaatgtc ttggttgaag
      601 aagcaggaga gcattatgct gttgttaaat ttaatggaac tgagattgga aggcaaatct
      661 ttgatatcaa ggtcaacaaa ccagtggaaa aaaattaagg agacgatacg gatgcttgat
      721 atagtaccat caaatacaca tcggagtggt agcttaataa attttgctgc gatttttgct
      781 tgcgcatcgg taattctagc atctccagtt gttgtggatg caagttctac tccgaaaact
      841 aaaaatgata atcaacttgt aattactaca aaaaatgaga ttaacacaat ttcaagtaat
      901 gatggcaaaa tttttgatgt gataaatacg gttttaaaaa gaaaagctga aatcaatata
      961 aaatatgatg aagatttaaa cttgtatttc tttgttatca aaacaacatc tgaattgttt
     1021 tcctcagatt acgatgtttt ggatactctc gataatgtat tatctgacta taaatatatg
     1081 gggaaatctg tagtagcaac tttgggggaa taaaatgttt gactttaatg aatatttatc
     1141 tatttccaaa caaattgaat cagatgataa atataattct aaagaatctt atagaagaac
     1201 tgctgtttca agagcatact acagtgcttt taaaaaatct gatgagtatt tgaaagaaaa
     1261 ttatgatatt atttataatg gaagtagcgg aaaaggaagc caccaaaccg tttggaattt
     1321 gttttcaaca gttaaggaat tgaatacctt aggaatacat aatagtgggt atagaatgtt
     1381 agagaaaaga aaatgtgctg actatattcc taatgaaacc attacgaaaa cagatatggc
     1441 gctgatgaat cgagaagcag aaaaaataat aaacaaactc acctaatgaa tttcaagcga
     1501 gtttgtttgt tattttttta tttaatcttt atacctttct ggatcaacga aagtatactt
     1561 tatatagtca taacgccgat gatcgcttcg tgcgtctggc acgtcagtca cgatatcaaa
     1621 caaaaagtat acatccttct tcattctagt tttcgcagca ggaattttaa tatactgaat
     1681 aatagaaaac aagtacttgt gccaaattat gtgccaaaaa aattcgaatt caacaaaatg
     1741 taaacaaata gaaaaccttc tatattaaga tttcctgcaa taacaaacac aacagaagac
     1801 gtgtaatagt tagtcaggaa cgtacaaata acccctgtat cctttgcggt acagggggtt
     1861 attttgtata agtagacatt gtagtttcta aactgctatg tcctaaacgt ttcgatacgc
     1921 taagtatatt tactccttga taaagtaaaa tagatgcatg cgtatgtctt agtccatcaa
     1981 taaacagtcg aagagaaaat agggaaaaat tgattactaa agaaaaactt actaggtcga
     2041 cggtgtagtt gattttcata cttcaataga ttcgaattaa acgatttcga ttggcttata
     2101 ccagtcctat ccaacgaaag atatatcgtt cttaactcta gcggtataac ttgaagcttt
     2161 acgtaaagcc aatgggaatg aactggagat gactttttat tatttttagt aatagctgat
     2221 gggttaatac ttacaacttt ccttttcaaa gtaccatata aaaaaacggt ggggttgttt
     2281 agcgaaataa aggatctaag ccaatagctt agatccttta ttctatgctt tatattattt
     2341 tttgcatgtg tgcgaaagta tactcaagcc caatcgccat ttcggaaaat cggtactgta
     2401 gagccatctt cacggattcc gtcgatatcc atcttgtcag atcctaccat gaaatctacg
     2461 tgggtttgac ttctattcaa tccagcttct gctaattctt catcggacat ttctgtaccg
     2521 cctttcacac tgaaggcata agcagaacct agtgctaagt gattcgatgc gttttcatca
     2581 aataatgtat tgaaaaagat gatgccagat tgagaaatag gtgaagggtc aggtacaagt
     2641 gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa gcagttttgc taagacatct
     2701 tctccttgtt cggcagaaaa atcaacaact tttccatctt taaaagtaaa tttcataccc
     2761 gagatgatgg tgccagcata actcagtggc tttgtacttg aaatgtaacc atctactcga
     2821 tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat ttgccatgaa tttttctcca
     2881 cgagcattat agcttccagc gccttcccaa agatggtttt taggcaatcc gataatgata
     2941 tctgtaccgg gagcagtata gtgaagggca gaaaattgtt ctcgattcaa ttcttctgct
     3001 ttttttgcta atttttcatc atgcttcttc catgctaaga cagggtcttc ttcatagaca
     3061 cgagtcgttt tgaaaatctg atcccataat gcctcaactt gtttttcttc tggcagttct
     3121 gggaagactt ttgctgccca ttgtttacca gccgcagcca cgacagtcca actgacttta
     3181 tttgcttgag ttgccttgcg taaattcatt agtgctttgc cattcgctga ttgataagac
     3241 gctactcgat ggctatctac accagcaaat gcatcgggat cggcagaaac aacgctgatc
     3301 ctgcttgctc ctttttcaag ccattcatcc gcttgatcga ttttagattg tggtacattc
     3361 tcaatacgat ccgttgcagc atgtaaaaga aattctcttt ggatctggtc gtcagtccat
     3421 tgaacgataa cctcagcggc tcctagttta taagcttctt gtgtgatcaa tcgagcaagg
     3481 ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc ctttttctgt ggctacgcca
     3541 gtttctgcaa ttaagcgtgc atattttttt agaagttcat taaaatcaga taacataata
     3601 aaaattcctc ctcaccattt tttctggtaa ctattagcat gataccattt aattatgatt
     3661 caaacaatga ggctttaaat aaaaaaagga ggttattttt ttaaggttaa gtttcatgat
     3721 atatgttact acttgctatt tcagcttgtg aagaaaatca aaaactaatt ttgcatatca
     3781 aaaaaacatg ttacaatgaa attaatcaat ggtggaagcg ttataaaaaa attaaggaga
     3841 ttaaaaaata tggcaagaaa aaagacgatt actagagaac agattttggc agctgcttat
     3901 gaagtagctg ccaccgatgg atttacacga tttactgcga gaaacatcgc gaacaaaatg
     3961 aattgttcca cgcaaccgat ttatcttgag tttaaaaata tggatgactt gagacaagct
     4021 ctttttgagc agatctatga tcatttacaa tatgaagtgt tcactgttga gcatacaggg
     4081 aatacgatta tcgatcttgc ttttaattat atccattttg caagaagaga gaagaagttg
     4141 tatcgttcac tgtacttaga agaatatggt ggaggaaaag agatgcagaa tttctcttat
     4201 acttactttg tgaatacagt gaaacgcgat ccagcttatg tgaatctttc agaagagcag
     4261 atcgaatctt tgtataatgg gacatggatc atagctactg ggatcgcagc tttgatgtct
     4321 tcaagcatca tccatccaac tgatgaacag attgaaaaga tgatccaaga cagtatagat
     4381 gctatcttga aattcaaaga accaatcgaa atcgattgaa tatactcaaa agttccacaa
     4441 atcagtaggt aacaagagat gtgtcaaaat aaggaaaagt tcgtttttct tacagcgtat
     4501 gcatttttaa ctcccgaaga actcttccat gaatgcaatg aataaaagag ccatacagat
     4561 tgaataaatc tggatggctc ttttattgca agtatattaa atttttgcga ctagttcttt
     4621 agcgaaagct tctaaatttt cgatatcttc ttcttcagca ttcagatcca ctttaacatt
     4681 ttcggctcct tttgatgcgc ctgtttttgc aaaagcagca tcgaaatcat ccaccgattt
     4741 gcagaattca tcgtaaaaag tatcaccaga tccgcagaca ccgtaaattt ttcccaatag
     4801 atccaattct tgcaagtctt cataaaagtc tacgatctca tcaggcagat cgccatcatc
     4861 gtatgtataa gtagctacta cgcaaatatc tgcctcctcg aattcatctg catctacttg
     4921 ggtacattcg ttgatttcga cttcgatatc cagattttca aatgcttctg caacaatatc
     4981 ggcgatttct tcagtgtttc ctgtcatgct agcatatacg atttttgcta aagccatgat
     5041 gtgcctcctc gtttataatt atttaacaat tatgaattat accaaaacat cattgaaaag
     5101 aaaataaaac ctaaagacac ctggggaatg tcatttggct aaatgtatgc cgctatgtta
     5161 aaatgagagg gatttgtaaa aaggagacga aaatatgatt actttaaaat cagcacgtga
     5221 aattgaaatg atggcagaat ctggagcttt attagcagat gtacataaaa atctgcgtga
     5281 ttttataaaa ccaggaatca caagttggga tattgaggta tttgtcagaa actatatcga
     5341 gagtcatggc ggaattgctg cgcaaattgg ctttgaaggg tatgaatatg cgacttgtat
     5401 cagtataaat gatgaaattt gtcatggatt ccctcgtaaa aagcctttga aaaacggtga
     5461 tttggtaaaa gtcgatatgt gtatcgattt gaaaggcggc atttctgatt cttgttgggc
     5521 ctatgtagtt ggagaatcta cacctgagat cgaccgattg atggaagtaa cgaagaaagc
     5581 tttgtacatc ggtattgagc aagcacaagt agggaatcgg attggtgaca tcggtcatgc
     5641 tatccaaact tatgtagaag gcgaaaatct agcgatcgtt cgtgatttta ttggtcatgg
     5701 cgttggtcct acgattcatg aagaaccagc agttcctcat tacggagaag ctggaaaagg
     5761 gttgcggttg aaagaaggca tggttatcac gatcgaacct atggttaata ccggaacttg
     5821 gaaaatgaaa atggatccta acggctggac tgcgtataca agagacggcg gactttcttg
     5881 ccaatatgaa catacattgg ctattactaa agatggtcca agaattttga catcacaagg
     5941 agaagaaggc acttattgat ctatccagtc aataggtacg ggagaggtac atgaaagttt
     6001 ggaacaaaat aaaacaaaat gaaaatctga tgcgctttat tgagacgact caaaagcgca
     6061 tcactgattc agaaatgagt acgacctctg tcgtcgttgc ttattattta ctcttgtctt
     6121 tatttccatt gattattgct tttggtaata ttttaccgtt tctccacatc gatcaagaga
     6181 ctgtactgac ctatttacga gaagtgattc ctgagaccgt ttaccagttt atcggtcctg
     6241 caatcaaaga ccttttgaca caaagttcag gaggcttgtt atccgtttct gcattagcgg
     6301 ctttatggtc tgcaagtcaa agtatcaatg ctttgcaaat tgcgatgaat aaagcgtatg
     6361 gcgtagaaaa tagaaaaaat tttttgatcg tccgtttctt ctcactaatt gtcattgtct
     6421 tgttcatgat tgctattagt ggggtaacta tcgttcttgg gttgggacag ctgattttgg
     6481 atgctattca gccaatcgta caaatacccg tgaactttat cgatcagttc caaactttga
     6541 agtggccaat cacattggta gctttatttg tcatcatgtt cttgatttat ttaattgtcc
     6601 ctaatgctca gttgaagttg aagacgatca ttccgggcac gatcttcgct actgtcggct
     6661 ggatgctgtt atcacaagtg tttagtatct atgctaggta ttttgcaacg aggatcagcg
     6721 gttatcagat cataggaagt tttattgtac tcatgctttg gcttaatttt gctgctacga
     6781 tcatcatttt gggcggaatc atcaatgcag ttgttcaaga atacgtgacg ggtcatcaaa
     6841 tcaaaaaacg tcgagatcca agccgaaaat ggttcaataa attgaaaact aaattttctc
     6901 ataaaaaaaa gtagaaacaa gagttcttat tgtaaattta tatcagtaat ttataataat
     6961 tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg gttataagat
     7021 tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc atttcagtac
     7081 aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca atgccttcag
     7141 cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta ttccgtaaaa
     7201 ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc atagtcacag
     7261 gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg atcttgattg
     7321 cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg cttcctttta
     7381 ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg atcttcggta
     7441 tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg atttcattga
     7501 tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct acagtgtata
     7561 ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct tacaattttt
     7621 atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt atgatggccg
     7681 tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct ttgctgatcg
     7741 tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa gcaaaccgtg
     7801 tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt ttaggcttta
     7861 ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct ttcacagcta
     7921 tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc atgttgtttg
     7981 ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag tttattttaa
     8041 aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag aaatatttga
     8101 agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct tattagtatt
     8161 gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc aactgtaaaa
     8221 gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga gtacaaaaaa
     8281 agactaacag agtataggaa atatccctac atcgatatct attttcatga tgaaaattcc
     8341 ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta tggcattatt
     8401 tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt gttattgaaa
     8461 gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg aacaactcag
     8521 cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt gcctttcaaa
     8581 tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg attgcctact
     8641 gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga tattgataaa
     8701 tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga caacgacttg
     8761 tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta tgcagttatc
     8821 catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt tttgacttct
     8881 atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca gaaatattag
     8941 tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga ccattaagca
     9001 aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct caaaggcagc
     9061 aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa aatcctggtt
     9121 tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt tgtctcgtca
     9181 ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt aaagtaacct
     9241 ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga caagtttctc
     9301 ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt gaaggcccaa
     9361 cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa tttctaaaaa
     9421 agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg ctgttttgga
     9481 aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa catgatcttt
     9541 cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta caagcagaaa
     9601 atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga caattattgt
     9661 taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg atgactttgc
     9721 gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat agctaccttt
     9781 aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct ttcagcagaa
     9841 gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat attaactgaa
     9901 tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg attgatcgct
     9961 aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc agaccaagat
    10021 gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca gaatccggat
    10081 cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga gatccatgat
    10141 tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat aagaagtcac
    10201 tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt gccgatcccg
    10261 tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa gactgggttc
    10321 ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga gattgaaaca
    10381 cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc gttgatcaaa
    10441 cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc atgacaaata
    10501 taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga gcagatatcc
    10561 atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt aacaaaggca
    10621 acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc aatgtctact
    10681 ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga tacaccacgt
    10741 ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata tgcagtacaa
    10801 gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat tggagatgat
    10861 agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc taaaatgttg
    10921 caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt caatgatcca
    10981 gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat tgaagaaaag
    11041 cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga caatgaggta
    11101 atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat tacggatgtc
    11161 aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg cggatttgct
    11221 tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat cgaaacaatt
    11281 gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg tatgggctac
    11341 atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca atacggtcaa
    11401 tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa cagatacaaa
    11461 attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg gtttcttcac
    11521 agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact ttgttcaaga
    11581 caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc aaaaaggaga
    11641 agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg tagtagtgga
    11701 tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat ctgaacataa
    11761 tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt tgacaccaaa
    11821 tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg ggggcatcgc
    11881 atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag cgattatgtc
    11941 ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc catttgttta
    12001 cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg ttaccggagg
    12061 tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc cagaagtgca
    12121 tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg ccggacttcc
    12181 tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag tggaccgtct
    12241 agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg ataattcatt
    12301 aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac ttttagaagc
    12361 ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt acggcgatct
    12421 tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat tcactgcgga
    12481 aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag atctgttagt
    12541 aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt caaacaacta
    12601 tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgagta tcttaagcgg
    12661 tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc atacgaatga
    12721 tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa cctatctgat
    12781 cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag aaatgatggg
    12841 ccaaccaaaa gacgcatacg accatgtaaa cgaccgcgca gggcacgatt tgcgttatgc
    12901 aatcgattcg acaaaattgc gagaagagct aggttggcag cctgagttta cgaacttccg
    12961 tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt ggaaaaaaga
    13021 aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag gaaatttcac
    13081 tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt taaaataaaa
    13141 atcaaggagc ggataaccat atgtttttat taactggagg aaatggacaa ttaggtacag
    13201 aattgcgcca tttattagat gaaaaaaatc tgccatatgt ttcaacagat gcaaaagact
    13261 tggatatcac agatgctgag aaaacaatgg cttatattac agaattaaaa cccgatgtta
    13321 ttttccattg cgcagcttac acagcagtag ataaagcaga agaagaagca aaagaattag
    13381 atgagaaaat caatgtcgat ggcacaagaa atgtagcact tgcagcaaaa gctgtgaatg
    13441 cacaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa aatgtagaat
    13501 acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa ttattaggcg
    13561 aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct tgggttttcg
    13621 ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc cgcgacaaac
    13681 tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg gcagaattta
    13741 tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg aacgaaaata
    13801 gctgttcttg gtatgagttc gcaaaagaaa tattgaaaga tacagatgta gaagttgcac
    13861 ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca gtcatgagcc
    13921 tgaaaaagac agaagcgtta ggttttgtca taccaacttg gcaagaagca cttgcgcaaa
    13981 tgctggaagc tgccaaaaaa atgaataagt aatttccttt ttatcaaata gaatttggag
    14041 catgatatgg aaaaacaaac aagaagtgca cgacgaaaag aaaagccaaa agcgaatcag
    14101 gcagattcga atttggtgct tgacctgttt ctaaaactcc gctatcttat tggcgtttta
    14161 gtcatcgtgg tcatcgttac ttttaattta aacggaagtt cacttggtgt ttgggataaa
    14221 tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga tttttggaca gaatcgggaa
    14281 gtgcggtcag acgaatggct ggtgcagaca cctttttacc tctcacaagc tgaagaggac
    14341 ttttcgttgg tgaacgagga ttattcatta aacggacaaa acatgatcat tgcgtataat
    14401 tctcctgtaa aggatattac ggttatcgga aaaccattca actggggatt ctttttcctc
    14461 ggaagagatc gaggactttc cttttattgg gcgatgaaat tagtcgtcat ggtcttgctt
    14521 ggattcgaag tactgatgat attaacgaag aggaaaaaag ctctatcgct aatcggtgca
    14581 tttgcgctga cattttctcc agcagtccag tggtggttca tgcaacatgt gggcgatttg
    14641 attttcttta ctttgggact gatgattgct ttttatcatt atttctacaa tcatgataaa
    14701 aaatggctac gaacgttgat gatgcttttg gtggttattt tcggtattgg gtttatttta
    14761 gtgatttacc cagcccatca agtgatgctg gcgtacttgc tgatttttta ttttgttggc
    14821 ctgcttattt actatagcaa gaaagtttca tgggatctgt tggatgtagt gttgattgga
    14881 ggggcagttt tatttattgg cggagtcatg gttcatttct ggctaacgtc aaaagacgca
    14941 ttgttagctt ctttgaatac cttatatcca ggaaaacggg taagtactgg aggaaagtgg
    15001 acgattggcg aatttttttc tttccttaca aattggaaaa ttccttttga agatatcaac
    15061 tattcgaata actctgaagt ggccctgttc tatcactttt ttccaactgt attcctagca
    15121 agtccatttg tgttatttgg caaaaaagat agcgaacaaa agttactggg acgtattttg
    15181 atgatttttt gtctgttttc tatcttttgg attaccgttg ggttgccaaa atggctagca
    15241 gaaatcactc tgctgtctta tgttcctcca ttaagagcca tccttacttt tagttttgcg
    15301 gcttgtttat tatcgatctg gtttatcgct tatatttgga gagaagatgt tattcctatt
    15361 tggtataaat tcattttgtt ggcagtaaat gcatggtctt atttctatgc gattacgcat
    15421 tcgaaaatgg ataattattt ttcggatttt gaaaccatcg cagttgctgt gttgggaaca
    15481 gtgattttag cttttgcatt atttggctgg agacgcttgt tttacctcgc ttttgtcgcc
    15541 ttagttatcg tatctggctt tttcgtcaat ccagtcgtag aaggtacagg agcgattttt
    15601 gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac aagatcctgg taaagtttgg
    15661 ttgtctgaag atgaattata taacttcacc ccaacattgg gagtgaaatc cttcaataca
    15721 gtacgctttt atccagatat agctgcatgg aagaaaatcg atccgaaaga agaatacgag
    15781 aagtattata atcggtatgc tcatacaaga gcttttatcg ctaaggaaga tacaaagttc
    15841 attttagatc gtccagatat gttttcggtc acgttgaatt ttgaagacgc agaaaaatta
    15901 gggatcgact atgtgatcag taaacgacca ttaactgatt acaaccaatt atatgaagcg
    15961 cagttcacgc agctatatgg accggataaa gacggttata tgatttttaa agtagaatat
    16021 ccggattatc cagatgtacc acaaacacaa actcaggaaa atcagctagt cgtacagtaa
    16081 taggctagct gagaataatc ctgaaatatt agtagaaagg agagtgaaga taattcaagc
    16141 aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc ttgcttttgt tgctgacgct
    16201 agtctttttt gtttggacag caggggtagg ttttccagca actttgttta tatataacaa
    16261 tagttcatta cttatcgctt ttagtgtggc tattttgctc attttaaatg tttataaagc
    16321 aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc cttttcattt tcttttctta
    16381 ctttcgggaa ttaagaaatg agtctttatt tggagactta ctgtttcctt tgattatttt
    16441 attttgttta gtaattaaat ggatcgagtg gacaaaatgg gatcgcggta tttatctgat
    16501 tgtctttacg gtcttcctcg gaatcacgtt atatcgtgta tttacagaga tccaagtacc
    16561 agaaggacaa agcatctggg ctccaggcaa ttcgctttct gatatttgga tcaatacgaa
    16621 tacaatcgga agttctttga tgactcttgc tttattgatc agtggatttg ccagttcttt
    16681 tgaacgatgg tatgttcgaa tcatcggtgg gatagcagtc gttgcagcct ttttaggtat
    16741 ttgggtctgc caatctagag gtgcattagt cgcgttgatt gtttttgcga tattggatct
    16801 tttacctaaa tcgttgatgc gtgtcattcg tgcgccattt attgcctaca cggttacgat
    16861 tcttttagct ttgccgattt cttatctggc ggctgtctct gaaaaagtca atttgtttac
    16921 cggtcgagaa gatatttggc ataaattcta tcagacgcta ggagaaaaat ctgaacaagt
    16981 tttactagga atgaaaacat ttatcttcca gcgaggaaac caatttttag gaaaccacaa
    17041 tagttataat tctattttga atatctatgg attgatagga tttgggattg ctgctttgct
    17101 gcttatcctt tttattggtc gcttaacgtt gaaagcagat ttatccaacg ggcagatgac
    17161 ttttatctgg gccttttttg cggtgatgat gcagtcattt atggaggata cattgacttc
    17221 atacccatgg gttccgatta tttatatcct gttggctatg gccgttcatc gatatgatga
    17281 accagaagtt acggaggaat tctatgttat ggaagaggca tatgacgata tgacttatga
    17341 tgatacatct tatgaggaac aaccagatag cgctcattct tccaggatcc aacgctatca
    17401 ttgataggca caaaatacga gagaggctgt gacaaccgtc gcagcctttt ttggtttatt
    17461 gcaattgtct agcatcttct gtaaaataga aacgttagag aaaatcttgt atcatagaaa
    17521 attaagaaag aaataagaac gcagctcggt accaaaaata tggtaaaatg gcacttgact
    17581 gtaattcact gaaaatcgct tggaggaaca caaatgttta aagatttgta tttatttatg
    17641 aaggacattt atcagaacag aaaattactg ctacagtttt cgatcaatga cttcaaatca
    17701 agatatgcag gatcgttttt aggaatctta tgggcgttta tcaatccgct atttactgta
    17761 ttgatttatt ggctggtatt tggtgttgga ctgaaagcac aaatgatcga tgcaaaatac
    17821 ccatttatcg tatatttagt taccgggatg attccctggt tcttcttctc agatgcattt
    17881 gcatcaacta cggttgtttt tcgggaatat acttatttag taaagaaagt cgtattcaat
    17941 attcgtatct tgcccacgac gaaaatccta tccaatctgt acacccattt attcttcatt
    18001 ctgattggca tagctgtcgc gcttataaat ggtatatatc cttcagcaat gtctttacag
    18061 ctgatttatt atttattttg catgtgtgct ttcttgacag gattgacttg gctgacggca
    18121 tcgatccaac catttttacc tgatatcatg caattaatta cgatcgtgct gcagttgatc
    18181 atgtggacat taccgatatt atggagccct aatcagtttg attcaggtct tgtaagcata
    18241 ttgaaattaa atccgctgta ctatgttgtt caaggttatc gtgagtcatt tttaagtgaa
    18301 gcttggttct gggagcatgg aacatatact ttgtatttct gggttttcac gttagtaatg
    18361 ttcgtaatcg gctctgcagt gttccgtaga ttgaaaccac atttttcaga tgtgctgtaa
    18421 ggagaatagc tatgacagaa tatgcaatta gactaaaaga tatcacaaaa tcttataata
    18481 tgtacgcaaa accttcggat cgatttcgtg aagccctcaa tccttttaag aaatcctatc
    18541 atgatgtatt ttatgcgttg aaaaacgtga atgtagaaat aaaaaaaggt gagatgatcg
    18601 gtttcgtggg agaaaacgga tcgggaaaat ctacaatgtt gaaaatcatt acgggagtac
    18661 tgacaccaac atccggcacg atggaaatcg aaggaaaaat ctcagctttg ctagaactag
    18721 gatcaggatt caatcctgag tattctggct atgaaaatat ctatttaaat ggaatggttc
    18781 taggattttc aagagaagaa gtcgatgaaa tggtcgatga tatcattgaa tttgctgaca
    18841 tcggcgacca tatttatcaa cctgtaaaaa cctattcaag tgggatgttc gttcgtctag
    18901 cttttgctgt agcgatcaat gtgaatcctg atattttgat tgtggatgaa gcattggcag
    18961 taggagatct tgaatttcaa ctaaaatgta tggaaaaatt tacagaaatc aagaactcgg
    19021 gaaagacgat tttattcgtt tctcatgata ttagttcgat tcgccgtttt tgtgatcgtt
    19081 cctattggtt gaaaaatgga aaagttgtcg aatatggtga tacgatggaa gtaacgacga
    19141 attacgaaaa ctttttgaag aaaaaatcag ttaaaacagt agatcgaaat aaaaaccaag
    19201 tagaacgctt cgcagctcca gatatcgtag acgtgacgaa agccgaattg ttggataaag
    19261 ataaaaatcc agtggatatg ctggaacaag gagaaaaact atacgttaaa gtaacctatg
    19321 aagtaaaaga cgatacaatc aaaaatccag ttttaggaat tgctctgcgt acagtcgaca
    19381 atttttatgt gtgcggactc aatactctac tagatggtat caagatccct tggaaaaaag
    19441 gtgagaatat cttttatctg gagtatgaaa agttaggttt gttagctggt gaatattatt
    19501 ttgacgttgc ggtctttgaa gaaaatgcaa cggttccttt ggtatacaag acaaaataca
    19561 tgaacttgtt tgtcagcggt tcttatatcg gagaaggcat cgtggtctta gaccataaat
    19621 gggaagaagg gactcatagc aatgaaatat gattttgaaa tggacctaga tgaacaaagc
    19681 agtgtgggaa aaattgccgc acagatcaaa ccaggaagta aagttttaga gtttggtcct
    19741 ggaaacggcc gattaacgaa acatttgatc ggagcaaaac aatgtgaagt gagcattgtc
    19801 gagctagata aggaattgtt cgattttgtc agcgagtttg cccaagatgg attttatgga
    19861 gatatcgaaa gttttgaatg ggcaaactat tatgctggac aaacatttga ttacgttttg
    19921 tttgccgatg ttttagaaca tttggtagat cctggaaaaa cgttgaagaa agttagagaa
    19981 tttttgaatg aagaaggaga aattctaatt acattcccta accttgcgca taattctgtc
    20041 atgattgatt tgttcaataa tcaattgcca tgggcttctt atggtttgct agatgaaacc
    20101 cataattctt tttatactca tgatggcttc caaaaagttt ttgaaaaagc aggattatac
    20161 atcaatattg aagattattt gtacttagct gtaggtgata cagaattaaa atcaacttat
    20221 gaagaattgc cggaagctgt acgttatgat ttcaaaatgc gaccatttgg cgaagtctac
    20281 caatacttct tctcattgat gaaacatcca gtagcacaaa gttccattgc gcagccgcaa
    20341 aattctaatt atgtgaaagt attagaagta atccagcaaa cgaaacaaga tgaaataatt
    20401 caacaaatac cattcaataa tttcacaggg gaaaatgaga cactaagttt ccatgtatca
    20461 gaattagcag aacgaatggt gtttcgcttc gcgcagcaac ctagctttat cgaattcagc
    20521 gcagaagctg ctggagaaaa actcacattt atcgattcaa atgctgtagt caaaacagta
    20581 aatgattgtt atttgtttga tggtaaagat ttaccagagt tctttttaac ggatattgca
    20641 gggaaagaag tgactatcca ttgtcactat cgttttatcg gagaattgac accaacaatg
    20701 aaagaattgc tggaaacaat ccgtccaatg gctgaagtta caaagcagct ttctgagaaa
    20761 aatgatgaat tagaaagaga aaatcattat cttattgaga ataatacaag attagatcag
    20821 acgttgaaaa caaccataaa tcgctattgc acgttgttgg aaagtgatga atggacaatc
    20881 aaacatagat tagggcgacg taagaaagaa acatcgaaaa aaatccaaga aaaagagctt
    20941 tctctatgta ttgacgaaaa aatctgggat gcagaaacaa agatattgaa aatcatcggg
    21001 tggggaatcg ctaattcgga tcgccaacca ttgtcctata agttatcagc cgaccaatca
    21061 ccattttttg aagcaattcc tgttttacga gaagaagtca atcaagcaaa acagctagct
    21121 gaaggagcaa aagcaggatt tgaactgcgg atcctttgcg agaaggaacg ttcattctta
    21181 gttgaagcag tggctcaaaa tggtcaatca tggatcattg aaatgtaaat aatgattaac
    21241 ttataaagat aaggagtaaa cgaatcgtgc aaaaaaaaga aattgccgta tttatcgatc
    21301 aaatcactcg tgaacgggcc actggcgatt tgcttattgt gggctgggca attgatgaag
    21361 tgaccaaaga aatccctacg ataaaggtag aaaaagaaaa tgtgattgct gaagcaacac
    21421 atgtcgtaag attggatatc aatcatttat ataatcttga tgttaagacc caaagcggtt
    21481 ttaaggtacg tttatcaggg aaaatgagag gaaaagcaat cttagacttc caaacagcaa
    21541 gacatcaaaa tggcatagct gtgaaattaa acggtaaata tccttatgat gacggcattg
    21601 aatcttcatg ggaaagaaaa aaaagattac tgaaaaaagg gataaattat gcaaggactc
    21661 atggcgtaaa aaaagcaatc cgccgggtca aactggaatt gaaaccagga tcgatcgact
    21721 atgcagagtg gatcagtcgt catgagaaac ctgatctgaa agagcaaagg aaagaagtac
    21781 aaggatttgc ctaccgccca ttgatttcca tacttatgcc tgtctataac gttgaaatca
    21841 aatggctcga aaaatgcatt gattcggtac ttgatcaaac gtatgatcac tgggaactat
    21901 gtatcagtga tgatgcttct actgatccag ctatccgaaa gtgtctagaa tcctatcaag
    21961 caaaagatga tagaattaaa gtcgttttcc gacaagaaaa tggacacatc agtctggcaa
    22021 ctaattctgc attgaaaatg gcagaaggag agtttatagc gctcttagat aatgatgacg
    22081 aattacctcc atttgcctta tatgaagtgg caaaagtgct aaacgtacat ccagaactgg
    22141 atttgatcta cagtgacgaa gataaaatcg atgcagatgg gaatcgcttt gacccgcact
    22201 tcaaagcaga ctggtctccc gatacattga tgggaaataa ttatatctct cacttaggcg
    22261 tatatcggac aagcattgtt aaggaacttg gcggtttccg taaaggatat gaaggctctc
    22321 aagattatga tttggttctt cgtgtgacag aacaaattcc tgcagaacac atttaccaca
    22381 ttgaccgtgt cttgtatcat tggcggacga tcccgggatc aactgcaagc aatggagaag
    22441 ctaaaagcta catctatgat tctggagtga aagcattgac agatgctcta tctagaagaa
    22501 atatcaaggg aagcgtacat cctggcagaa tttctggttt ttatgaaatc acttatgatg
    22561 ttttgcaaga agacttggtc agtgtgatca ttccaactaa gaatggctat gaagatctaa
    22621 aaacttgtgt ggattcgatc atcgaaaaaa cgtcttatcc aaattatgaa atcattattg
    22681 cagataatgg aagtacagat cctaaaatgc aagaattatt tgcagaatac aagcatcagc
    22741 tgaaagaccg atttatcgtc gaattaattg acattccatt caattattca cgtatcaaca
    22801 atctggcagc agaaaaagca aacggcaaat actttttatt cttgaataac gatacagaag
    22861 tgattgaacc tgactggatg acagcgatgg tttcttatgc acagtttgat cgaatcggct
    22921 gtgtaggagc aaaattattt tatccggatg atacaacgca gcatgcaggt gtattattag
    22981 ggatcggtgg cgttgcagga catgcattga ataactatga tcgaacacat tgtggttact
    23041 ttggccgatt ggtcattgac gtcaattact tagcagtcac tgcagcttgt atgatggtca
    23101 aggcagctga cttcaatgct gtcaatggat ttgatgaaat attagaagta gcattcaacg
    23161 atgttgactt gtgcttgaaa gtttatgaac tgggtcgtta caatgtctat gcacatcaag
    23221 cagaattgta ccatttcgaa tctaaatcaa gaggttatga agatacacca gaaaaacaaa
    23281 gacgttttgc tggggaaatc aaaaaaatgc aagataagtg gccttcttat attgctcatg
    23341 acccatttta taacgataat ctaactaaag aaggaatcgg cgatttttcg ttgagacctg
    23401 attgattaaa agaactgtat tttcattttt attaatgaaa atacagttct tttaatttaa
    23461 tt
//
LOCUS       DAIGUC010000048        21956 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.048, whole genome shotgun sequence.
ACCESSION   DAIGUC010000048 DAIGUC010000000
VERSION     DAIGUC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.048"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..260
                     /locus_tag="NOB46_002024"
     CDS             <1..260
                     /locus_tag="NOB46_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1058953.1"
                     /translation="AAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNP
                     GNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            505..1530
                     /locus_tag="NOB46_002025"
     CDS             505..1530
                     /locus_tag="NOB46_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1058954.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLRIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            1824..2933
                     /locus_tag="NOB46_002026"
     CDS             1824..2933
                     /locus_tag="NOB46_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI1058955.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASANTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            3016..3912
                     /locus_tag="NOB46_002027"
                     /pseudo
     CDS             3016..3912
                     /locus_tag="NOB46_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            3928..4752
                     /locus_tag="NOB46_002028"
     CDS             3928..4752
                     /locus_tag="NOB46_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058956.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINIFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGGKL"
     gene            4784..6094
                     /locus_tag="NOB46_002029"
     CDS             4784..6094
                     /locus_tag="NOB46_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HCI1058957.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSRAYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            6242..7501
                     /locus_tag="NOB46_002030"
     CDS             6242..7501
                     /locus_tag="NOB46_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1058958.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            7511..8383
                     /locus_tag="NOB46_002031"
     CDS             7511..8383
                     /locus_tag="NOB46_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1058959.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            8395..9225
                     /locus_tag="NOB46_002032"
     CDS             8395..9225
                     /locus_tag="NOB46_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1058960.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            9265..11448
                     /locus_tag="NOB46_002033"
     CDS             9265..11448
                     /locus_tag="NOB46_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI1058961.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLQERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            11509..12729
                     /locus_tag="NOB46_002034"
     CDS             11509..12729
                     /locus_tag="NOB46_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HCI1058962.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKYSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVCLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            12726..14186
                     /gene="gtfA"
                     /locus_tag="NOB46_002035"
     CDS             12726..14186
                     /gene="gtfA"
                     /locus_tag="NOB46_002035"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HCI1058963.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVTQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            14263..15369
                     /locus_tag="NOB46_002036"
                     /pseudo
     CDS             14263..15369
                     /locus_tag="NOB46_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            15691..15900
                     /locus_tag="NOB46_002037"
     CDS             15691..15900
                     /locus_tag="NOB46_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI1058964.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            15893..16042
                     /locus_tag="NOB46_002038"
     CDS             15893..16042
                     /locus_tag="NOB46_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCI1058965.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            16196..16330
                     /locus_tag="NOB46_002039"
     CDS             16196..16330
                     /locus_tag="NOB46_002039"
                     /inference="COORDINATES: protein motif:HMM:NF026010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058966.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     "
     gene            16490..16861
                     /locus_tag="NOB46_002040"
     CDS             16490..16861
                     /locus_tag="NOB46_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1058967.1"
                     /translation="MTVMRLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPE
                     TASSIRTIELDDNTITFLKAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIV
                     GVHIIRIHGLRHSHASLLISQ"
     gene            complement(17145..18230)
                     /gene="xerS"
                     /locus_tag="NOB46_002041"
     CDS             complement(17145..18230)
                     /gene="xerS"
                     /locus_tag="NOB46_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HCI1058968.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            18564..18797
                     /locus_tag="NOB46_002042"
     CDS             18564..18797
                     /locus_tag="NOB46_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HCI1058969.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            18794..19201
                     /locus_tag="NOB46_002043"
     CDS             18794..19201
                     /locus_tag="NOB46_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI1058970.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(20338..20856)
                     /locus_tag="NOB46_002044"
     CDS             complement(20338..20856)
                     /locus_tag="NOB46_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HCI1058971.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         7469 a         3359 c         4118 g         7010 t
ORIGIN      
        1 tagcggctaa attagtaaaa tttttaaaaa ataagaataa acgagtgatg gaacaattat
       61 cgattattgg atttgatgat attacttttg cagaattaat ggatcctgcg ttgacaacaa
      121 tacgactaaa tccaggtaac aagggggcga ttgcttttca ccaactgatt ggactggcca
      181 aacaagaaga aataaaaaat caagtactac tattagaggg agaattgatt tctcgagact
      241 ctgttcacaa aatcaaataa aaaagctctg tgaaataagt atagttaaca ataaaatatc
      301 cgaacgatag agagaatgaa ctgtgatcta gcagttcctc gtcggaaatt cactagaatt
      361 agcattattt actctaaatt gttcggatat tttttcttgt ttttaattat gattacagtg
      421 cctattttta acgaaatttg cttattttca aaatgtatga ttatatttta gtaaacactt
      481 tcaaatatga aaagaggagc tattatggta ggaattaggg atgttgcaaa acgggcgggt
      541 gtgtccattg caacagtatc gcgcgtgcta aatgaggatc cgacactttc agtaaccgat
      601 gaaaccaaac gaaagattgc agaatcggtt aatttttatc attatgtcaa aaaaagtccc
      661 gttgcaaaaa atttaacaaa tattgcatta ataacgacag tttctgaagt agatgagttg
      721 gaagatccct attttcgaac gattcgcaga gggattcaag tcgaagcaga acaaagcaaa
      781 gtcaatttga agaaaattat tcgtttgtca gaaacaccgt tggagcaaga tgatttgcta
      841 aaatgtcaag gtgtgttgat tattgggcag gtgctatctt ctgtgattga agaagtatca
      901 gcaattaatt cgaatgtcgt agtgattgat gaccctagta ttgaagctga agtagatgca
      961 gtttatactg atttaacaaa agcaacgaat cagcatttag atcgattgta taaaaaagga
     1021 caccgaaaca ttgcgtttat cggaggagga cgtgttcgtt tagatagcca aggaaataaa
     1081 cacgtgtcag atgatgatta tcgaaaaata gcctatgaga cgtggatgaa acaaaaagga
     1141 ttagaaaaat atagtcaaat ttatttagaa ggctggacca cacttgacgg aatgcaggca
     1201 gcagatttac ttttgaaaaa acatgctaaa gataagttgc cgactgctat catggtagga
     1261 aatgatccta ttgctgtggg ggtttatcgt tcacttcaaa aaaatggtct acgtattcca
     1321 gaagatattt cgattgtgag ttttgataat attgaagttg ctgaattttt aacacctgca
     1381 ttaaatacgg tgaatgtgaa tacagaagaa attggaaaac tagcagttcg catggttaat
     1441 gaacgaataa aagaagttag aaatgtttcg atcaaagtga ttgtttctaa taatattatt
     1501 gttagagaaa gtgaaaaaaa tatcgattaa aaaagtaaac atccaaaaaa ggatgtttac
     1561 ttttttgttt actaatattt ttagtaaaaa atctcgacaa aacattaagt aaacagttat
     1621 ggtgttgtta acaaaaagaa aacgcattca aaacaggagg aattaagatg aaacatttca
     1681 aaaaaatagc tttaacaggg atagctgttt taactgggac attactcgca gcatgtggtg
     1741 ggggagatag taattctaaa gacgggcaag taactttaag ctatgcgagt tgagatactg
     1801 accaagctcc aggactaaga aaaatattag atgaatttga aaaacaaaat cctgatatca
     1861 aagtagaaat ggagacaacg ccttgggatc aatattgggt taaattagaa gctgcaacaa
     1921 cgggaggtaa tatgccagat gtagtaacca tgcactctag cgaatcctat aaatatatgt
     1981 cacagaatgc tttgatggga cttgatgatg ttatcaaaga aaatgatatt gacatgggaa
     2041 actttactga aggaattgct gatttctata cgcttgaaga cgaactatac gcaatcccta
     2101 aagatgcttc tgtagtgggg ctatggtaca acaaagaatt atttgataat gcaggtgtcg
     2161 attatccaga tgaaacatgg acatgggaaa cactcagaca agctgcaatt gatttaacag
     2221 atgaatcaaa aggcatctat ggttttgcat cacatattgg aacagagact ggctactggc
     2281 catttattta tcaaaatggg ggagaagtat ttgccgatga caatacaaaa tcaggtttga
     2341 ataccccaga agcacaagaa gctttagctt tttatcgaga tattgcactt gttgatcatg
     2401 cttcaccaac aattacagaa ttacaagatc ctgataagtt aagtcgtttt caatcaggta
     2461 gattagcaat gatgattgaa ggaaactggt ttgcaccggg atttttgaaa aatgactatc
     2521 tagttgaaaa tgttgcttct gccgtgttac ctaagggaaa agttaatgca acaattacaa
     2581 atggacttgg ttgggctgcc agtgcgaata caaaataccc agaagaagtg aaaaaactaa
     2641 tggcattttt agctagtgag gacgccaata aaatccaagc ggaaacgggg gcatcaatcc
     2701 cagcactaaa aggctttgaa gacgagtggg ctgcttcttc agatacaatt gatttgagtg
     2761 cttttggaaa aatgttggag tatggagtcc ctcgtccata caataaagat ggattacgag
     2821 ctgaacaagc agaagttcaa attattaacc gtattctgtc tggtgaagta actgttgaag
     2881 atggaaccgc tcaaattgaa aaagaagtca atgcgatatt gagcggaaat taaattagtt
     2941 aattatacaa tatacaggcg aaaggattct atttcgtctg tatattaatg gatgaatacc
     3001 aaaaaggggg atattatgaa aaatcgaatt tttggaaaat atcgtaaaga tcaagtgata
     3061 tggggctata tttttatttt tccaacggca ttaggattaa ttttattaaa tatatggcca
     3121 gcaattcaaa cagcaatttt aagttttcaa aaaacggtag ggttcggtga tactgaatgg
     3181 gtcggattaa gaaattacca aaaaatgttt gcagacggtg aagtttttca gtctttatta
     3241 aacacattaa tttatgcagt ggtttcgata cctagtattg ttgtattatc cttgttggtg
     3301 gcagttttaa tgaatagaaa agttaaagga ttgtcgattt atcggacaat ttattttcta
     3361 ccagtcgttg ctgcaccatc cgcagtcgca atgatttggc gctggatgtt caataatgat
     3421 tatggactga ttaataacat gttggctaaa ataggtctcg atggaccagc atggttaacg
     3481 gatccatcga ttgcgattta ttctattatc attgtaggag tttggagtgc tattggttat
     3541 aacatggtgt tattactagc cggcttataa gaaattccta aagattatta tgaagcagcg
     3601 gaaattgatg gtgctagtcc aatccagcag tttttcaaca ttacgttacc attagttaca
     3661 ccaacattat tttttgtagt tgtaacaaca gttatcaatg ctttccaagt atttgatgtt
     3721 atttttatga tgattactcc taatagtacc gccatgttta aatcacaatc attagcctat
     3781 ttattctata aacattcatt tattttaaat gacaagggat atggttcggc aatcgttatg
     3841 ttccttttag tgattatatt aattattact gcaattcaaa tgaagttgca gaaaaagtgg
     3901 gtaaactatt aaggaggcta tcaaattatg aaaaataaat ttttttcaaa tgcgccaatc
     3961 catatcatgc ttattttagg tggtattgca atggcattac cttttatttg gatgatttta
     4021 acttcaggga aaacgttggt tgaatctacc caaattccac ctacaatttt ccctgagaaa
     4081 tttcagctaa gtaactatca acaagtactt gatttattac cattcatggc tttttatatc
     4141 aatatatttt taatggttgt tggacgagtg attggctcgg ttttattttc agcaatggct
     4201 gcatatgctt gtgcgcgtct aagttttcca gggaaaaata tccttttcag cttagtactt
     4261 attcaaatga tgattcccgg ttccattttt attactccac agtatttatt agcacaaaaa
     4321 ttgggtattt taaatacaat tccagcatta atattaccag gggtagttag tgcgtttggt
     4381 acgtttttat taagacaatt tttcttaggt ttgcctgatg aattggagga agcggcctat
     4441 ttagaaggtg ccaatatttg gacgatcttt ttcaaaatta tgttgccgct tgctaaatca
     4501 ggattggttg cacttggaat attcacagcg ttgtttgcat ttaaagattt aatgtggcca
     4561 ttgattgtca atacttcaat tgataagatg cctttagctc cgggattagc aaacttacaa
     4621 ggacaatatg ccacgaactt cccacaatta atggcaggtt cgttattagc aatttggcca
     4681 atagttgtga tattcatcgt tttccaaaga aaattcattg aaggaattgc tacaacaggt
     4741 ggtaaattat aaaactatta attagtgatt ggagagtaag tacatgacaa aaattacatt
     4801 tattggtgca ggaagtacta tttttgcaaa aaacgtatta ggcgatgcga tgttaactcc
     4861 aagtctacaa gatgcacata ttgcattgta cgatattgat gaaaaacgac taaaagaatc
     4921 aaatttaatg cttaaaaata ttaataaaaa ttcgaatgaa aatcgtgctg atattgtttc
     4981 ttattatgat cgcaaagaag cgttaagaga ggctgatttt gttatcaatg ctattcaagt
     5041 gggtggttat aaaccttcaa cagtgattga ttttgatatt cctaaaaaat atgggttgcg
     5101 acaaactatt ggtgacacca tggggattgg tgggattttt agaaccctac ggacactacc
     5161 agtaatgtta gactttgcta aagaaatgga agaagtttgt ccaaatgctt ggttattgaa
     5221 ctatacaaat ccgatggcga tgttaaccat gggtgtttta aaagcgacga gtattaagac
     5281 tgttggttta tgtcatagcg ttcaagtatg cgtaccagaa ttgtttgagc atttaggaat
     5341 agccgatcaa tatgacttaa atgactttca atggaaaatt gcaggcatta atcatatggc
     5401 attcttgttg gaaattacaa aaaatgggga agatttctat ccaacaattc gtcagttagc
     5461 tgcagaaaaa ccaaatccac atccagattc tgtacgtttt gaattgttga aacgttttgg
     5521 ttactatatt acagaatcaa gtgaacacaa tgcagaatac catccatact ttattaaatc
     5581 aaaataccca gaattgattg acgaattagg gattccgttg gatgaatact tacgtcgttg
     5641 tgaacaacaa attaatgatt gggaaagcat gcgagaggac attgtaaata atggggagtt
     5701 aacacatacg agaagccgtg catatgcttc atatatcatg gattctatta cgacaggaac
     5761 tccgtcagtg attgcaggaa atgtcttaaa taaaggctta atcacaaact taccgacaga
     5821 tgtttgtgtg gaagtacctt gtttagtcga taaaaatggc gtgcaaccaa cctatgtcgg
     5881 tgaattgcca acacaattag ctgctttaaa tcggacgaat atcaatgttc aagaactgac
     5941 agtagaagcc gctttaacac tagataaatc aaaaatttat caagcagcgt atttagatcc
     6001 acatctatca tctgaattgt ctttaacaga tatcaaaaat ttagtggatg atttaatcga
     6061 agcacatggg gactatttac ctgaatataa ttaaaaagaa gctgaaagag taaggaattt
     6121 tcaattcctt actcttttct tagttaaatt tagtaaaaat attgacaaaa cacttagtaa
     6181 acagttacat tagtgttaac aaaaagaaaa cgcattcaaa ttgtataagg aggagcataa
     6241 aatgaagtgg tctaaaaaaa ttattttagc ttgtatagca ctaggagcaa cgatctcttt
     6301 gactgcttgt ggaaaaaatc aggaagatgc aagcggtaag gtagaaatag agttttttaa
     6361 tcaaaaaaaa gaaatgactc aaacgattca ggagattgct aaagattttg aagcaaaaaa
     6421 ccctgatatt catgtaaaag ttgtggatgt accgaatgct ggtgaagtaa ttaaaacacg
     6481 tatgcttgca ggcgatgtac cagatgtcat taatctttat cctcaaagta tagaattgaa
     6541 agaatgggcg aaagctggtt atttagagga cttaaccgaa gaaccgtatt tagagaatat
     6601 caaaaatgga tatgcacaac gttttgctat tgaggatcgt gtatatagca taccattaac
     6661 cgctaatgtc tatggttttt actataacaa aactgctttt gaggaaatgg ggattcaagc
     6721 accagaaact tgggcagaat ttgaaaaaat agtagctgag attaaagatc aaaacaaagt
     6781 accgtttgcg attgcaggag cagaaggctg gactttaaat ggttatcacc aactagctat
     6841 agcgactgct gctggtggtg aagaggaagc gaacaatgtt tggcgtttct cagaagttaa
     6901 tggaattaat gctgaaagca aagaaatgca aaaagatttt aatcgattag atttgttaag
     6961 agaaccaaaa gctttgcaaa acaactggca aggtgccggt tataacgata cagtagttac
     7021 ttttacaaaa ggtgatgcgt tgattatgcc gaatggttca tgggcaatgc cgatgattca
     7081 ttcacaaaat ccagattttg aagtaggaac ttttcctttt ccagcagatg aagcaggtca
     7141 aagtctaacg attggcgcag gagacctagc cttatcagtt tctgcaactt ctcaacataa
     7201 agaagaagcc aaacgttttg tagaatatat gacaacacct gaagcgatgc agaaatatta
     7261 tgatgtagat ggtgcaccgt gtgctgttga gggcgttatc gagaatactc aggattcacc
     7321 attaagtggt ttaactgaac ttgcttttac tgatcgtcat ttagtttggt tagccaaaga
     7381 ttggaatagt gaaaatgatt tttatacctt aacaacaaat tatttacaca atggcaatca
     7441 aaaagccatg attaacgcat taaatgcttt ctttaatcca atgaaagctg acggaaggta
     7501 ggaaaataaa atgaaaataa aagaaatttt aaatcgttac tgggcaatca tttttgtagc
     7561 aattccaatt attttgcaga tgattttttt ctactttcca atggttcaag gtgcttttta
     7621 cagtttaact aattggactg gtctgactta taattttgat tttgtgggtt tgaacaatta
     7681 taagattctt ttttctgatc cgaagtttat caaatcgatt ggcttcactt taattgtgac
     7741 gctttgcatg attgctggac aaattggttt tggtattttg attgcgcggg cgttgaacgc
     7801 aaatattaaa gggaaaacat tctttagagc atggttcttt tttccagcgg tcttatcggg
     7861 cgtggttgtt tctttagtat ttaaacaaat ttttaactat ggtttaccaa aaattggtag
     7921 tatgttaggc attgaatttt tacaaaccag tcttttagga acaacatggg gagcgatttt
     7981 tgcagtaatt tttgttttac tttggcaagg aattgccatg ccagtcatca ttttcttagc
     8041 gggttttcaa agtattccac aagaaattat tgaagctgct agaatggatg gggcgaatga
     8101 taagcaaatt ttttggaata ttgaaatcac ctacttatta ccaagtattt caatggtatt
     8161 tattatggca ttaaaaggtg gcttaacagc atttgatcaa atttttgctt taactggtgg
     8221 tggaccaagc gatgccacaa catctttggg gttacttgtt tataattatg cttttaaaaa
     8281 caatcagttt ggttatgcga atgctattgc tttagtctta tttatcttaa ttgggattgt
     8341 ttcactggca caattaaaat tatcgaaaaa atttgaaatc taggaggttt cccaatgaaa
     8401 acatcaaaag aaaaaaatat ttctaaatac ttgcttttat tattaggggg cttcatgatt
     8461 ttagttccct tagtttcaac gctattcggt tcatttaaaa caacacccga tattatgaat
     8521 aatttctttc gttttcctaa tccagcgact ttggaaaatt tccgaagatt gttagcggat
     8581 ggaattggtc attacttttg gaattcggca atcatcacaa tcattgcagt agttgctgtg
     8641 acagcaatta ttcctatggc tgcttattca ctagcaagaa aaatgactcg tgggaaagca
     8701 tacggattga tgtatttatt tttaatttta ggaatttttg ttcctttcca agtaattatg
     8761 attccgatta ccgttatgat gagtaaaatt ggtttagcaa atatgtgggg attaatctta
     8821 ctctatctca cttatgccgt accacagaca ctatttttat atgttggttt tattaaacta
     8881 aatgtgccta tcagtctgga tgaggctgct gaaattgatg gggctagtca ctttacaact
     8941 tatttcaaaa ttgttttccc aatgttaaaa ccaatgcatg cgacgactat tattcttaat
     9001 gctctatggt tttggaatga tttcatgcta ccattattaa ttttaaatcg tgattctaat
     9061 atgtggacac taccattgtt tcaatataat tatacgggac aatattttaa cgactatggt
     9121 ccaagttttg cttcctatac agtaggaatt gtcacgatta cactagttta tcttgctttc
     9181 caaagaagta ttatagctgg aatgagcaat ggagcagtga aataaccaat aaattattct
     9241 cattataaag gagttcataa acttatgatt atatttgaca atcacacaca aacatttcat
     9301 ttacaaaata aaaaaattag ctatctatta ggaatcgaag aaaataatta tttaacgcat
     9361 ctttattttg gaaaaaagat tacgcactat tctggtgggt atcgctaccc ccgaacagat
     9421 cgttccttct cacccaacaa tgcaaatgcg caagatcgtt tattatcttt agatacatta
     9481 ccattagaat ttccaggata tggacatggt gattttagag aaccggcgca taatattaaa
     9541 ttaggaaacg gtagtcgtgt aaatgatttt cgttatgata gctacgaaat tcaaaaagga
     9601 aagcccagct tagcgggatt gccagcctta tatacggaag atgatgatga agctgaaacg
     9661 ctgattattc aattgaaaga cgcgattagt ggattgactt tacagttgtt ctacacaatt
     9721 tatcaaaatc acagtgtaat tattcgttct acgcaattag taaataatag tgatgaaaca
     9781 gtggagatta accgcttagc tagtcaatca attgattttc caaatcgtcc actcgagtta
     9841 attcatttaa atggtacctg ggcaagagaa cgtcaaatga ctagagaaaa aattcataca
     9901 gggataaaag tattagatag taaacgcgga tcaagcagcc atcaacaaaa tccgtttgtt
     9961 gctttagtag atgccaaaac agatgaattt caaggagagg catatggatt taatttagtt
    10021 tatagcggta atcacgaaac ggtgattcaa aaagatccat ttgaccaaac acgggtcatt
    10081 atgggaatta attcatttaa ttttggttgg caactaaaaa ctggcgactc atttcaaacg
    10141 ccagaagtcg tgatggttta tagtaatgaa ggtctgaata cgttatcaca gacgtatcat
    10201 gaattgtata atcaccgttt aattcgtgga aactatcgtt tacaagaacg tcccacgtta
    10261 atcaacaact gggaagcaac gtattttgat tttaacgaag aaaaaatcat gaatattgtc
    10321 gatgatgcga agaacttggg cattgaaatg tttgttttag atgatggttg gtttggcggt
    10381 cgtgaaaatg acttcacttc attaggtgat tgggttgaaa cagaaggcaa acttgcttgt
    10441 ggtttggaaa atttagccaa gcaagtgcat gataacggga tgaaatttgg gatttggttt
    10501 gaaccggaaa tgatttctga agatagtgaa ctatttcgag cacatccaga ttgggcattg
    10561 ggtattccag gtcgtgaccg ctcaattagt cgaaatcaat atgttcttga tttttcaaga
    10621 caagatgttc gtgataatat ctatcaacaa atgacggcga tttttgatcg tgtaccgatt
    10681 gattatgtga agtgggatat gaatcgaaat atgacagaag tctattctgt cttgttggac
    10741 tcaacgatgc aaggtgaagt ggctcatcgt tatatgttag ggttatatga atttttagaa
    10801 aagttaacaa cgaattatcc aactatttta tttgaaagtt gttcgggtgg aggcggtcgt
    10861 tttgatgcag gtttcttgta ttacatgcca caaacttgga cgagcgacaa taccgatgcc
    10921 gtggctcgtc tgaaaattca atatggaacc agcttagtgt atccaatttc aagtatgggt
    10981 gcgcatgttt cagcagtccc aaatcatcaa acaggaagag aaacgagttt aactattcgt
    11041 ggcaatgctg cgatggctgg tgtttttggt tatgagctag atctaacgca attaacttct
    11101 gaagaaaaag cagaaattaa agaacaagtt gccttttata aaaagcatcg ccaacttttg
    11161 caatatggaa ctttttatcg cttggaaagt ccgtttgaag gcaatgatac tgcatggatg
    11221 tttgtctcaa aagaccaaac agaagccatg gtcttttatt tccgagtatt agcagaagct
    11281 gcgcatccat tagtcacatt gaaattagca ggattagcag aagaagcaac ttatcaaatg
    11341 gaagatgtaa catttgctgg cgatgaattg atgaatctcg gtttttatat tgactcagaa
    11401 ctacatggtg attatgcgac acaacgcttt tatttgaaac agatatagta gcttgaattt
    11461 acaatataag tgcaacacca aaagagactc attccaaacg aagaaaatat gttttattta
    11521 cacgcattta ctaaaaagca gcctgatttg aattgggaaa atgaagaagt acgtgaagaa
    11581 atctatgcaa tgattaacta ttggttagat aaaggactag gcggatttag aatcgatgcg
    11641 atattaaaca tcaaaaaaaa actagagtat ggcatctttg aatctgatgg agaagatggg
    11701 ttagccttca ttgggccctg gattcttaat cagtcgggca ttgaagtgtg gttaaaagaa
    11761 atgagagagc ggacatttaa accacataat agtatgacgg tagcagaagc cgatgttcct
    11821 aatgaacgtt tagatgaata tattggtgaa gatggctatt attcgatggt ttttgatttt
    11881 agttatacgg atattgatgt acctgaaact ggtgaatggt ttaaatatag ccaatggaca
    11941 tggacggata tgcgtaccaa tatttttacg aatcaattag ttacgcaaga taaaggttgg
    12001 ggcgccttat atttagaaaa ccacgatcaa ccacgttcaa ttaataaata tattccagaa
    12061 gaatggatca atgattatag taaaaaaatg ttggcgacgc tttttatgtt actaagaggt
    12121 acccctttta tttatcaagg acaagaacta ggaatgacca acatagaaat ggcatcatta
    12181 gaagattttg atgatgtagc tacgcattct cagtataaac gggcattaga atatggattg
    12241 gcaccagagc aagcattgaa agctgtcaat aaacgaagtc gggataattc tcgcacacct
    12301 atgcaatgga atacgcaaaa aaatgccaga ttctcaactt ctgataatgt atgtttaaaa
    12361 gtaaatccta attatccaga actcaatgca gaagctcagt taaccaatca acagtcggta
    12421 ttcaattatt atcatcaatt aattaaatta agaaaaaata gtgtatacaa agacgtgcta
    12481 atctacggac aatttctacc agtgaaagat aaaaatgaac atattttgct ttatgaacgc
    12541 caattagaag ataaaatcgt attagttatc ttaaacgtta cagcaacaga acaagaatat
    12601 tatgtagatg aacagtacca acaagtatta atcaataatt atgaagatgt tttattagat
    12661 caaagtcgaa aattgcgttt acgaccgttt gaaagtattg tattagctaa ttatggagga
    12721 caattatgaa aattaaaaac gaagcaatgc tcatcaccta tgcagatagt ttaggaaaaa
    12781 acatgggcga attaaaacaa gtcttagaca aacatttaca aggtgttatt ggtggtgtac
    12841 atctgttgcc tttttttcca tcgacaggtg atcgaggctt tgcgccgagt gattatacga
    12901 cagttgatcc agctcttgga acatgggaag atgtggaagc attaggtgaa gattattatt
    12961 tgatgtttga ttttatgatt aatcacattt ctcgtgaatc aaaatttttc caagatttca
    13021 aaaaaaacca tgagcagtca ccatacaaag aaatgtttat ccgtattcat gaatttttcc
    13081 cagaaaatcg accaacacaa gaagatattg atttaatcta caagcgtaaa gacaaagcgc
    13141 cgtttcaaac ggtagaattt gcggatggta cgacagaaga ggtttggaat acctttgggg
    13201 aagaacaaat tgatttagat gtgaccaaag aagttgtgaa agaatttatt cgagaaacca
    13261 tcaaagatat ggcgaaccat ggctgttctt taattcgatt agatgcgttt gcttatgcga
    13321 ttaaaaaatt agataccaat gatttcttcg tggaaccaga tatttgggaa cttttagacg
    13381 aagtgcgtca agaagcagcg aaatatgacg tcgaattatt accagaaatc catgagcatt
    13441 attccattca aatgaaaatt gccaatcatg attattatat ctatgacttc gccttgccaa
    13501 tggtcactct gtattcactt tatagtggaa aatcagaacg tttagccaat tggttgaaaa
    13561 tgagtccgat gaagcagttt acaacattgg atacgcatga tggaattggt gttgtggacg
    13621 ctcgtgattt attaacagat gaagaattgg attacacctc tgaggaattg tataaagtcg
    13681 gggcgaatgt gaagaaggtc tattcaagtg ccaattacaa taatttagat atttatcaaa
    13741 ttaacagcac ctattatagt gcattaggcg ataatgaccg tagctatctg ttagcacgtg
    13801 cgattcaagt atttgcgcca gggattccac aaatttatta cgttgggtta ttagcaggaa
    13861 aaaatgatat tgaactgttg gaagcaacga aagaagggcg taatattaat cgtcattact
    13921 atgatttagc cgaaattgaa gaagaagtgc aacggccagt gactcaacaa ttatttgcac
    13981 ttttaaaatt tagaaatgaa tctgcggcgt ttgatttgga tggaacgatt gaagtagcaa
    14041 cgccatcaga atcagaaata gtgattacac gtaaaaataa aaacggtagt gatagtgcaa
    14101 cattaacggc taacttggat acgaaagaat ttatcattga gtctaaagat ataaaaattt
    14161 tcactagtgt tgcattaaaa ttttaaccta ttccatagaa caaaaaatcc tttatactag
    14221 cacttggatg acttatccaa gaccaataaa aaggactcat acatggataa gtataaaaca
    14281 aatacagcat ttaataaatg gttttctgcc ataaaattag gaaaactttc tgtcaactcc
    14341 caaaaatgta tttttgatta caattcgtat cgtaaaaaac tgtcttttga agctgtgctc
    14401 aagctctttc tctacgcagt taatgaagaa aaagaaagtt tgcgtgattt gagtacagct
    14461 cttatcgacc gatcgctcca actagaaacc gatgtgtcat cgattagtca tacccaattg
    14521 tctcgagcat ttaatgcact tgaacctaaa gtgttagaag aaatttttca acaactgtta
    14581 gaaaaagttc aacatcaaat caaaccaacc aagcgaaatc atctgtatct gattgattcc
    14641 agtacgtttt cgcttagttt aaaacgtcat aagtgggcga ctttccgtca aacaaaatca
    14701 ggtgtcaagt tacacttaaa ctattgttat atggacgata ctacgatgta tccaactgat
    14761 tttaccttaa caaatgccca tgaacatgat ctcaatcaac taccagtatt ggtgaatcaa
    14821 ccagaggcaa cttacgtgtt tgatcgtggg tattaggact ttgaaaagat ggatcagatg
    14881 cattgggatg gctatttctt cgtcactcgg attaaaaaaa acaccaaagt tcacgtgata
    14941 gatactctgg aaacatcgcc agaaacagaa attctacgag acgagctggt tcgtttagga
    15001 tctaaaacct atctaaccgc caatttccga ctagtcactg ttcaagataa gaacggacgt
    15061 gtgtttcaat ttatcaccaa tcgaatggac gtctcttcaa aagaaatctc tgatatgtat
    15121 cacgctcgtt ggcaaatcga attgtttttc aagcacatca aacaacacat gaccattaaa
    15181 accttctttt ctcaaagtga aaaaggcgtg cagaatcaat tgattttaac gatgatttcc
    15241 gctctcctca cgtttctcat caaattggag acgaaaacgg aaaaatcagt gttccaaatc
    15301 aaacgattct ttcgttattt actgtttcag ccctttgaat gttgtctaga aaaattaatt
    15361 cccacatgag aaaaaagaaa tttggctcgt tacttttggt tttcagttga ataacagata
    15421 aaaaattttc tggaaaaagt catcctctgc gtcagcacag ttttttttga cttattttca
    15481 gaggaaatag ttttcagaat attctaaaat gttttatgca acactagtga tattttttag
    15541 aattagattt ctaatgtgca ttttttgagt attaaggagc aagtatacaa agatttataa
    15601 agctgattaa atttgaataa aaatatgcag gaacgctact atttttagta gtgttctttt
    15661 ttatatttga ataaaaaatg tggtggttaa atggtggtta taacaaaaaa tgaattaatg
    15721 aaattaggtt atgggaagta tcagtctgag agaatcatac gacaggcaaa agcaattatg
    15781 gtttcaaaaa gctataccta ttacgaaaat agaagattag gactagtacc tgttgaatct
    15841 gtagaagaag ttttaggtat gaagatagag gtagaggagg attttcagaa tcatggttaa
    15901 ttttaaaaaa gataaaaatg ggaaatatca ttttactgct agtttgggat tcgacaaacg
    15961 aacagggaaa agagtacaaa aaaacgtaga ggggttaaaa cagttaaaga agaaaaaaag
    16021 cgtataccga acttgtttct aattatggaa aagaagcaga aacttctcaa agtactatgt
    16081 tgtttgagga gtttttttat aaattattcc taccttatta tcaagggaaa gtagaagaaa
    16141 gaacatataa aaatcggtta tctacaatca aaaaaacttt tcttatttct ttaaaatgga
    16201 gttaagagaa atacgtccaa ttgacattca aaagtggcaa aataatttat tgagcaaata
    16261 taaaaattct tatgtaagaa acatgtatgg gatttttcag atgtcattag atcgagcagt
    16321 tgttttgtga ctacttgaaa aaaatcctgc aaaagttatt ggaaatgtga agaaaaggaa
    16381 aactacagtt gatttttgga caaaagaaga atttacaaaa gttatttcaa ctttttatat
    16441 tgatgatttg taccaacatt ttggttttat ttgtatgtgg ttacttttta tgaccgttat
    16501 gcgtttggga gaagccactg cattaacttg gaaagatatt gattttgaaa ataaaaactt
    16561 gcgtgtgaat aaaacactct attataagag agccaaaacc tatgagtttg tagaacccga
    16621 aacggcttct agtattcgta caatcgaact agacgacaat acaattacct ttttaaaagc
    16681 ttggaaggag cgtcaagttt caataggagg catgtcgttt gtactttctt ataatggaac
    16741 acctactcag aaatatacaa tccgtcatat tatgagaaga catgcaacga tcgttggtgt
    16801 tcatataatc cgcatacacg gattaaggca tagtcatgct tctttgctta tatcacaata
    16861 aaaagatgca cttcgaatta aagaaaggtt aaaacatgct gatgtacaaa cgactttagg
    16921 aacttatggt catttgtatc taaattcatt gagagagata acaaatgatc ccacagatta
    16981 tatccaaact aatttttcta aaatcaaacc gacacctatt tacgataata aaaaataaat
    17041 gataaacaaa agtaggatca caccaaaaga aacacactag aaaaactata atacaggctt
    17101 ttctagcgtg ttgtttctta tttccgccta tttatacatt atactcataa agcatttaat
    17161 gcatcgatcg tagccgcatt gtctatatgg gtatataaag ttgttgtatt ggtacttgaa
    17221 tgtcccaatt gttgggcagt taataccaat gaatttgtct gttggtagag tctagtagct
    17281 aatgtatgac gcagtttgtg agggctgact tgaattctaa agccttttga atattttgct
    17341 accatccgtt cgattgcaat accggatata cgcttggctt ctccttggta aattgctaga
    17401 aataaagctt tttcgttttc tgttacttta tatcgttctt tccgaatagc tagataatta
    17461 gctaaatatt ccattgcgaa tgctgctata ttgacagcat ctcttttatt tccttttcta
    17521 gttactacca cattattctt atctaaagat aggtcatcta aattaatatt tataacctcg
    17581 gagagtctca atccagatcc taaaatcagt gcattgatcg ccaggtctct ttctacatct
    17641 cgttgataat agatcaaagc tcgtttactc aaagtatttt tatattcatt ggcaatataa
    17701 tctagataat tttgtgtatc cttatctaga aataattttt tctcaatggc attggcacgt
    17761 gcagctaacg tagttttatc tgtgatggtt gctacttgat ccataggatt attgtctaag
    17821 tatggttttc ctagaggatt attggaactt ttcgaaagat atttaaatag aacctttaat
    17881 gccgtgatat ttctattgat agtagaagta gatagaccta agttattatt atctttgagc
    17941 ttagtttttg ttgtctcttt ttttacattt tcttttgtgc gacgtttcaa atgagatttg
    18001 tacaagttta ggtcataggc agttaactgt cttatcgagg tgatagaagt atcaggaacg
    18061 atagactcac tcagaagcca ttcataaaag agcttataat tttttagata ttctaaagtg
    18121 gttcgaggtg attgatcttt atcctcacga tcttgaacaa aatcttttat ataatcgggc
    18181 atatgaagta tgattgtatc tattttttga tatatttctg tatttttcat gtcattcatc
    18241 ctttcaataa gtaggggaga agagtatctc tataattgga ctataccaat tatagaatgt
    18301 tttgtcaatt ggtatgctct aaaatttatt aatttgtttc aaaaaaagca tataaacagg
    18361 tatacgttta ataatttaaa ataaatggta tacataaata gggaaggaaa tagaagggag
    18421 caatctaaat tttttgaatt ttcttaatta attatataga aagaacaatc tttctataga
    18481 gttagacatg agagggacta tgcttgattt aaaatcaaca agcgtatata ctgtatatac
    18541 aaagaaaaag gagggagaag actatggcaa ttaaagaaag aaaatttagg gaagtgggga
    18601 actcagtagt attaactatt tcaaaggagt ttcttaaaga aaatgggtta aatcccggag
    18661 atacggtttt tttagatgaa gaaaaacttc gagcggcaat tacaaaaaaa caagccttat
    18721 ctgatgaaat tgatttagca atatctcaag cattaactga atatgatact acttttagag
    18781 agcttgtcga taaatgagta ttcattacct agaagccaaa gatattataa aaatgaatgt
    18841 aatccaaata aaaaaatact ctcctaatga accccttggt gtaaaggatg cgaatgcttt
    18901 agaaatgtgt gtagggcaac ttcgagcctc agcttttggt gaagaggttt atccttcgat
    18961 ttatgaaaaa gcagctatcc tacttataca attgataaag aaacatcctt ttcacaatgc
    19021 aaataaacgt actgctttct tagctacttt tgtctttttg aaaatcaatg gacagctttt
    19081 agctattgat caaaaagatg ctgtaaattt agcggtatat attgctacgt atgataagga
    19141 tttcgatcaa ctaaaatatg aagtgatcaa cactataaag acacatacgc agcccattta
    19201 aggagttact gtatgtgtct ttatagtgtt attagctgct atagcgaaat aattgaagta
    19261 aattacaaat agctataatt caaatccaag tatatagaaa acgtaaattt tctatatagt
    19321 tggattaaga taacgactat ttattttatc atatttttac tgtaccctat acttttactt
    19381 ggtatattta tgaataatcg caaatttacc cctatactac tagtttgtaa gttagattaa
    19441 taaaaatact aaagttattt gttcttttat taaatacacc tacaacttat aaattgatgg
    19501 tatttagata acgcgaaaga ataaaaataa cagctgatag taaagtttgt tgacgattgc
    19561 tactcaatcg aaagtgagtt agtgcgtatg aacttgcttc tgaaaactta tgaaatgaaa
    19621 gaccttttac atcttgcaga aatcgttact gggattaaac taagcaataa aaactaatgt
    19681 tcccctcatt ctttgaactt ctactatttg atttatttat tctgataaat gacgatttca
    19741 ccttcaggat cttcaaatcc cgtatagaat ttatttaaga tctcttcagt atcagtaata
    19801 ggataggcga taggccacat accctttgat ggttagaata aactgctcaa aatctgtatc
    19861 gtatgttggc tttagcatat taacaaaggc tatctccaaa ttataaacca taagcgttga
    19921 atcgttctta acaatttcaa ttcttcctaa cccaaagtca gaagatataa ttaccggact
    19981 tgccttaccc ttcatgtggg ttgttgagat tccatattta aagggaattg tcggtactat
    20041 cggcggtctg aaaaacatcc caaaaataaa aaaatctttc ccctgctagt ctcctaagtc
    20101 cctttgcagc ggatatggca ccataatctc attttatcga agtgagtcat ggtttatctg
    20161 ttggccaacc aaaattgata caatctaacg atgcaccctc tacggcattc taggggagtg
    20221 cacttgcatt cacccaataa aaaccggcag ttagcaaaga acttatgtag tcgtatgttc
    20281 ttactgttaa catacaagag gtctcctttc cacaattgct tagcagtaaa cgggaattta
    20341 caaagctaat ctcttccatt ttcttatctt tgttctaaaa gtcccaaatg gagcaactgt
    20401 atttacatga ataaatttat atacttccca tacagccgtt ttggttgcct cgtctgccca
    20461 ttttcttttg tgtgcagtga atagatcttc atcactcatt gaatcaatca tcatgttaat
    20521 atcatcaata ttacgattga gaatttcctc taattctttc aatggtagat gtgcataggt
    20581 atttgtaaac cacttatata actctcctaa ctgattccat ttaaattgat cagaaggcgt
    20641 tttaacagat aatccatttc tttcatcatt ttcccatttt agaattaaat tcgtccaacc
    20701 aacttgatat gctaaatttt cagcaggtgt tctatccact tcctcaactc ttttatcctt
    20761 caattcttca ggaatagttt caaattctaa aatatattta gtataagtcc tatttatttc
    20821 tttttttaat tcttctttat ttttatatgt tctcattata ttacctccat aaattcctaa
    20881 ttgtctcctt taattcatct ataatttcat ccacgatatt ttaatccgtt ctacaatgca
    20941 tatctgatat gcattgactg tctaactcat atgtgaatga tttataaaat atcccaacgt
    21001 ctcatctaaa gaaatgttga tcgtcagcaa ggagctaaaa aatacgaata tatttctttt
    21061 gtagtaaaat cggactggtt tgcatatcat tttcttcgta aatatcaaaa tcatgttaac
    21121 tactatcaat tactaataaa aactaccact ttaagcgtta agaactgtta agtttagtta
    21181 agtgaggata gttcacaaaa tccattgtta aacttcacga aagtggtaaa actcaaaatg
    21241 ctttatatag gattacagca tcgctctttc ttcgattgcg cgttgggtaa aaaatattat
    21301 gaagtaaaaa ttgacgatga cacgttcctt acggctcatc agatgaaaca gctacaaaaa
    21361 cgaaatgatc aactcgaaga aaatttaatt ctaaaaaagc gattgccata ttcacgcctc
    21421 gctcgacgaa ctattaaagg tcaagattta cctgaagatc atccttttta ggaaattgaa
    21481 gctttttatg ttgcacaatg catttataat actacaatga tgttttcacc agatattctt
    21541 ctagggtgcg gtgtaatgaa acagatacac ttgcaaaaga aaattcaccg cgaatttact
    21601 aaaattatga ataattatgt taatcttccg aaattttttt ccaaaattaa gggatcaagc
    21661 tggtgttata gattgtttaa ggttggcaaa aaaataactt ctttttaaac aattatagaa
    21721 aaccgatact ctgttaagtt ggttgacacg gtatcgattt ttatgacttt cttattctga
    21781 aacttcacta acggacagta cctaaaaagt ctatagtatg gacgtttacg agtactattt
    21841 tatcaaaaat gctgctcatt tcaacttata tgttttagtg aactaccccc acttagctaa
    21901 acctgacggt tcttaacgct tgaagtggga gcttcttggg aacagagcgt acttga
//
LOCUS       DAIGUC010000049        21282 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.049, whole genome shotgun sequence.
ACCESSION   DAIGUC010000049 DAIGUC010000000
VERSION     DAIGUC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.049"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            133..507
                     /locus_tag="NOB46_002045"
     CDS             133..507
                     /locus_tag="NOB46_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI1058972.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="NOB46_002046"
     CDS             complement(621..1250)
                     /locus_tag="NOB46_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI1058973.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="NOB46_002047"
     tRNA            complement(1384..1456)
                     /locus_tag="NOB46_002047"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="NOB46_002048"
     tRNA            1670..1743
                     /locus_tag="NOB46_002048"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="NOB46_002049"
     CDS             complement(1881..2045)
                     /locus_tag="NOB46_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058974.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="NOB46_002050"
     CDS             2340..3668
                     /locus_tag="NOB46_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HCI1058975.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="NOB46_002051"
     CDS             3870..4703
                     /locus_tag="NOB46_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCI1058976.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="NOB46_002052"
     CDS             4719..5456
                     /locus_tag="NOB46_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HCI1058977.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="NOB46_002053"
     CDS             complement(5611..6579)
                     /locus_tag="NOB46_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCI1058978.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="NOB46_002054"
     CDS             6811..7644
                     /locus_tag="NOB46_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCI1058979.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="NOB46_002055"
     CDS             7678..8517
                     /locus_tag="NOB46_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1058980.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="NOB46_002056"
     CDS             8543..9103
                     /locus_tag="NOB46_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI1058981.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="NOB46_002057"
     CDS             9302..11023
                     /locus_tag="NOB46_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HCI1058982.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="NOB46_002058"
     CDS             11188..12330
                     /locus_tag="NOB46_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI1058983.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="NOB46_002059"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="NOB46_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCI1058984.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="NOB46_002060"
     CDS             14130..14777
                     /locus_tag="NOB46_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI1058985.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="NOB46_002061"
     CDS             15170..17815
                     /locus_tag="NOB46_002061"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCI1058986.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="NOB46_002062"
     CDS             18125..19438
                     /locus_tag="NOB46_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCI1058987.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVITGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="NOB46_002063"
     CDS             19428..20081
                     /locus_tag="NOB46_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1058988.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="NOB46_002064"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="NOB46_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI1058989.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="NOB46_002065"
     CDS             20978..21178
                     /locus_tag="NOB46_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1058990.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7185 a         3551 c         4445 g         6101 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaaactttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggcgatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gatcgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattag ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtaa taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg ta
//
LOCUS       DAIGUC010000050        21240 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.050, whole genome shotgun sequence.
ACCESSION   DAIGUC010000050 DAIGUC010000000
VERSION     DAIGUC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.050"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(132..509)
                     /locus_tag="NOB46_002066"
     CDS             complement(132..509)
                     /locus_tag="NOB46_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1058991.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            764..1492
                     /locus_tag="NOB46_002067"
     CDS             764..1492
                     /locus_tag="NOB46_002067"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCI1058992.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1492..1746
                     /gene="purS"
                     /locus_tag="NOB46_002068"
     CDS             1492..1746
                     /gene="purS"
                     /locus_tag="NOB46_002068"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HCI1058993.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1748..2419
                     /gene="purQ"
                     /locus_tag="NOB46_002069"
     CDS             1748..2419
                     /gene="purQ"
                     /locus_tag="NOB46_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HCI1058994.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2420..4642
                     /gene="purL"
                     /locus_tag="NOB46_002070"
     CDS             2420..4642
                     /gene="purL"
                     /locus_tag="NOB46_002070"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HCI1058995.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4627..6066
                     /locus_tag="NOB46_002071"
     CDS             4627..6066
                     /locus_tag="NOB46_002071"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCI1058996.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6089..7141
                     /locus_tag="NOB46_002072"
     CDS             6089..7141
                     /locus_tag="NOB46_002072"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCI1058997.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7138..7716
                     /gene="purN"
                     /locus_tag="NOB46_002073"
     CDS             7138..7716
                     /gene="purN"
                     /locus_tag="NOB46_002073"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCI1058998.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7713..9248
                     /gene="purH"
                     /locus_tag="NOB46_002074"
     CDS             7713..9248
                     /gene="purH"
                     /locus_tag="NOB46_002074"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCI1058999.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9264..10538
                     /gene="purD"
                     /locus_tag="NOB46_002075"
     CDS             9264..10538
                     /gene="purD"
                     /locus_tag="NOB46_002075"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCI1059000.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10660..11574
                     /locus_tag="NOB46_002076"
     CDS             10660..11574
                     /locus_tag="NOB46_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI1059001.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11707..13272)
                     /locus_tag="NOB46_002077"
     CDS             complement(11707..13272)
                     /locus_tag="NOB46_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI1059002.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13265..14716)
                     /locus_tag="NOB46_002078"
     CDS             complement(13265..14716)
                     /locus_tag="NOB46_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1059003.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14730..15746)
                     /locus_tag="NOB46_002079"
     CDS             complement(14730..15746)
                     /locus_tag="NOB46_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1059004.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15966..17054
                     /locus_tag="NOB46_002080"
     CDS             15966..17054
                     /locus_tag="NOB46_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HCI1059005.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17108..18634
                     /locus_tag="NOB46_002081"
     CDS             17108..18634
                     /locus_tag="NOB46_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCI1059006.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18636..19841
                     /locus_tag="NOB46_002082"
     CDS             18636..19841
                     /locus_tag="NOB46_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1059007.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20098..21075
                     /gene="guaC"
                     /locus_tag="NOB46_002083"
     CDS             20098..21075
                     /gene="guaC"
                     /locus_tag="NOB46_002083"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCI1059008.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
BASE COUNT         6809 a         3594 c         4822 g         6015 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa cgaacaaaaa
      721 acgatgtatt tgcttttaat gtaaataaaa aggagagacg tacatggaga agaaagaact
      781 tttgtatgaa ggaaaagcca aaaaaatata tcttacttct gatgagaact tgatttggat
      841 agaatattta gatcaagcaa ctgcgttgaa tggcgcgagg aaagaccaga taagtggaaa
      901 aggagaattg aataatcaaa tcacaagtgc aattttccgt tatctgactc aaagaggaat
      961 aaaaaatcat tttattgaac aattgtctaa aaccgaacaa ttagcaaaaa aagtacaaat
     1021 tatccctctg gaagtggtta tccgaaatat tgcagcagga agtttctcaa aacgtctagg
     1081 tgttcccgaa ggtaaagaat tcatcaaacc aatcattgaa ttctactata aggatgacca
     1141 gttggatgat ccatttatca atgaagagca tatctatttc ttacaacttg caaagccgga
     1201 agaaatcagt gagctgaaag cccaagcgtt ggctattaat gaaattttga ccgaattatt
     1261 tgctaaggtc ggtttggttt tagtagattt caagctagaa tttggccggt cgaatggaca
     1321 aattttgctt gcggatgaag taacaccgga tacttgccga ttatgggatg aacgtacgaa
     1381 tgaacatatg gacaaagacg tttaccgcag agatctaggt gatttgatcc cagtctatca
     1441 agaagtatat aaccgtctat cggaactaac tgaagaaaag gagcgagtat gatgtatttc
     1501 gtaaaagtat atgtaaccta taaagattca gtgttagatc ctcaagggga ggcagtaaaa
     1561 aaagcagtcc atcgtatggg atatgaaaca atcgaagata tccgaatagg aaaatacttt
     1621 gagatacaac ttgctgatgc agaagaacca atcgatacag tgattgaaac gatttgtgac
     1681 aagctgcttg caaatgtaaa tatggaaaca taccgatatg aaatcaaaaa aatggaggaa
     1741 gtataacatg aaatttgcgg tcatcgtttt tccaggttca aattgtgacg cagatatgtt
     1801 atgggcagtt cgcgagatca tgggcgctga tgccgaattt gtacggcatg atgagtcctc
     1861 tttagaagga tttgatgggg ttttactgcc gggaggattc tcctatggtg actatttgag
     1921 atgcggtgcg attgctcggt tttctacaat catggaagaa gtgattcgtt ttgctgaaga
     1981 agggaaacca gtattcggta catgcaatgg attccagata ttgacagaag caggactttt
     2041 gccaggtgta ctgagacgaa atgagtcttt gcattttatt tgcaaaactg taccattgaa
     2101 agtcaacccc aagacggcct ttacttcaga gtatgaagcc gacgaaataa tctatcttcc
     2161 agttgctcat ggggaaggaa attatttctg tgacgaagaa acacttcaag aactaaaaaa
     2221 aaataatcag attgccttta cttataatga caacatcaac ggcagcgtgg aaaacattgc
     2281 agggattacg aacaaagcag ggaatgtgtt aggaatgatg cctcatccag aacgtgcagt
     2341 agaagacttg ctaggatcag aagatgggaa acggttcttt gcttccattt taaaaaactt
     2401 cggaaaggtg accgtataga tgaaaacatt gaaagaaccg acagctgaag agatcaagaa
     2461 aaaaagaatc tatgccgaat ggggattgac tgatgaagaa tatcgaatga tcgaagaaga
     2521 tatcttagga agaatgccta attatacgga aactggactg ttttctgtta tgtggagcga
     2581 acattgttcc tataaaaatt ctaaaccggt tctacgcaaa tttcctacta gtggacctca
     2641 tgtgttgcaa ggccctggag aaggcgcagg catcgtcgac atcggtgatg gactagcagt
     2701 tgtcttcaaa gcagaaagtc acaatcatcc ttcagccgtg gagccttatg aaggagctgc
     2761 gacaggagtt ggcggaatca tcagagatat tttcagcatg ggggctcgtc caattgcgtt
     2821 gctagattca ttgaggttcg gcgaattaga taatccaaga acgaaatatt tactagaaga
     2881 agtagttgca ggtatcggcg gatacggcaa ttgtatcggc ataccgactg taggcggcga
     2941 aattgcattt gatccttgtt atgaaggaaa cccattagtc aatgcaatgt gcgtaggttt
     3001 gattgaacac aaacatatcc agaaagggca agccgctggc gtcggtaatt cgatcatgta
     3061 tgtaggtgca aaaacaggtc gcgacggtat ccacggagca acttttgcct cagaagaatt
     3121 taatcaagaa gaagaacagc aacgttctgc tgtacaagta ggcgatcctt ttatggaaaa
     3181 gctgctgctt gaagcgtgtt tggaattaat cttgcatcat tcggattctc taataggtat
     3241 acaggatatg ggagcagcag gacttgtttc atctagtgcg gaaatggctt caaaagctgg
     3301 ctcaggactt atattgacat tagatgaagt cccacaaaga gaaactggga tgacacctta
     3361 tgaaatgatg ttatcggaat cacaagaacg gatgttgatt tgtgttaaat caggagagga
     3421 agaaaaaatc caagaactat ttcagaagta tgatctagat gcagtcacta tcggtaaagt
     3481 aacagacgac gggcaatatc ggctatatca tcaaggagaa gaagtagcaa atctgccagt
     3541 cgatgcatta gctgaagatg caccagttta tcataaagaa atgaaagaac cagctcgaat
     3601 cgtagaattt cagcagttag ctccttatca gccagttatc gaagaacctg gacaagtatt
     3661 gcttgatctg ctgcagcaac cgacgattgc ttcaaaacgt tcaatctacg aaacttatga
     3721 ttcacaagta caaaccaata cagttgtccg tccaggaagc gatgctgctg tgatgagggt
     3781 tagagggacg aataaagcgt tagctatgac cacagactgc aacgcgcgct atctgtattt
     3841 ggatccaaaa atcggaggac aaatagcagt ggcagaagct gctagaaata ttattgctag
     3901 cggtggtaag cccttggcga tcaccgactg cctgaactat ggttctcctg ataaaccaga
     3961 agttttttgg gaattatcga cttcagctga cggaattgct gctgcgtgtg aaacgttagg
     4021 aactcctgtt atttcaggaa atgtctcttt atataatgaa acggatggtc aagcaatcta
     4081 tccaacacca atgattggta tggtcggatt gattgaggat cataaacata tcactactca
     4141 ggaattcaaa aaatcagggg atctaatcta tatattaggt aagacgtttg cagattttga
     4201 tggcagtgaa ttacaaaaga tgcagcttgg aagaatcgaa ggtgtgatcc gaaactttga
     4261 tctatccatt gaaaagagaa accaagagtt agtattgaca gccatccaaa acggattgat
     4321 tgaaagtgct catgactgtt cagaaggtgg cttggcaatt gcactggcag aatcagcttt
     4381 caaacatcag ctagggatat ctgtacagtt tgaattgtcc tctgctcaat tatttgcaga
     4441 aactcaatca agatttgtgt tgacagtcgc accggaaaat aagacacgat tcgaagaaat
     4501 gatgggagat gctgctgttt tagcaggtaa ggtgacggat gaagcgataa tcgaaatttc
     4561 agcaactgac ggtcagatca aaatagaaac tgcagtagca agaaagtgct gggaggatgc
     4621 aatcgtatgt cttatgaagt gaagagttta aatgaagaat gcgggatctt cggtgtttgg
     4681 ggtcatccag acgccgctag tgtggcatac ttcgggctcc atagtcttca gcatcgagga
     4741 caagaaggtg caggtatcgt gtccaatgat cgaggaaagc ttaaggggca tcgagatttg
     4801 gggctgcttt ctgaggtatt caaagatcaa agaaaattgc agcagttaac aggagaagct
     4861 gcaatcggac atgtacgtta tgcaacagca ggcaatggaa gtgtggacaa tattcagcct
     4921 tttctattca aatttcatga tcagtcgatc ggcttagcgc ataatggtaa cttgatcaat
     4981 gctcgttccc ttagaaaaga gttagaggaa aatggggcga tcttccattc taactccgat
     5041 acggagatat tgatgcattt gatccgacga agtgaagaaa cagatttttt aaataaatta
     5101 aaaagtgctt tgaatgaagt caaaggtggc tttgcctatt tattaatgac agaaacggca
     5161 atgattgccg ctttggaccc aaatggtttt cgtccattag caatcggaca aatgaaaaac
     5221 ggagcatacg tgattgcctc ggaaacttgt gcattagaag ttattggggc acgttttata
     5281 agagatgtcc agcctggtga gatagtgatc atcaatgacg aaggaatcca gattgattgc
     5341 tttacgaagg acacgcagct ttctatttgt tcgatggaat atatctattt tgccagacca
     5401 gattcaaaca tcgcagggat caatgtgcat actgcacgga aaaatatggg acggaattta
     5461 gcgaaagaat cgccagtaaa agcagatatg gtcgttggcg tacctaattc ttctttgtca
     5521 gccgcaagcg gttatgcgga agctagtgga atcccttatg aaatcggatt agtaaaaaat
     5581 caatacattg cccgaacatt tatccagcca acgcctgagc taagagagca aggtgttcga
     5641 atgaaattat ctgctgtacg aggagtagtg gaaggtaaaa aggtgattat ggtcgatgat
     5701 tcaattgttc ggggtacgac aagcagacgg atcgtccatc ttttgaaaga agcaggggca
     5761 aaagaagtcc atgtgaggat tgcttctcct cctttgaaat atccatgttt ttacgggatt
     5821 gatattcaaa cgcgtaaaga actcattgcg gcaaatcaca cgattgatga aatcaaagaa
     5881 tgtatcggtg cagattcttt aggtttttta agtgaagagg gtctgatcga atcgatcggt
     5941 ctggaaaaag atgctccgta ttcaggattg tgtatggctt atttcaacgg agattatccg
     6001 acgccgttat atgactatga agaaaaatat caggaatcac taaaagaaaa agtatcgttc
     6061 ttttaaaagc agaccaagaa gggagtatat gaattcaatg gcaaatgcat acgcaaaagc
     6121 tggcgtagat gtcgaagctg gatatgaagt agtagaacgg atcaagaagc atgtcaaaaa
     6181 aacggaacgt ttaggtatga tgggcgctat aggaggattc ggcggttgtt ttgatttatc
     6241 ggtctttcaa ttaaaagagc cagtccttgt ctcggggacc gatggcgtgg ggacgaaatt
     6301 agcagtggca atcgaagcag acaaacacga tacaatcggg atcgactgcg tagcgatgtg
     6361 tgtcaatgat atcttagcac aaggcgcaga gccgttatat ttcttagact acttagcaac
     6421 ggggaaaaat gatccgttac gtttggaaaa tgtagtaaaa ggtgtagcag atggatgtgt
     6481 tcaaggaaat atggcgctga ttggcggaga aacagctgaa atgcctggta tgtactcagg
     6541 taatgattat gatctagccg gatttgctgt agggatagct gaaaaatctc aattattgac
     6601 aggagaaacg atcaacccag gagatgtgtt gcttggaata gcatctagcg ggattcattc
     6661 aaatgggtac tctcttgttc gcaaaatttt ctttgagcag cagcagtttt ctttatcatc
     6721 aaaactgcca gaattgaaaa aaacacttgg cgaagaattg cttgagccaa cgaaaatcta
     6781 tgtttcttcc ttgcttccgc tgatcaaaga aaagaaaata aaaggagctg cacatatcac
     6841 tggtggaggg tttgtagaaa atatcccgcg aatgttacca gaatctatgg ctgcacaaat
     6901 caaacttggc tcatggccga ttcttccaat attcggctgt ttacaaaaat atggtgaaat
     6961 tcctgagatg gagatgtatg aaatcttcaa tatgggcatc ggtatggtcc tggcagtcga
     7021 agaatcgaaa gtaaaagaaa tagtacacga aattgagcaa gctggcgaaa aagtttatga
     7081 aatcgggaaa gtgatcgcca aagaaaaaca tcgtgtggtg tttataggag aagaacgatg
     7141 agaatcgctg tttttgcttc tggaaacgga agcaactttc aagcgctagc cgattatcta
     7201 tcgaaaaaag gattggaatc ttcgattgac tggttgtttt gtgatcagcc tgaagcatat
     7261 gttttgaaac gtgcaactgc gttgagtgta ccggcagatt gtttttcacc taaagaattt
     7321 gattcaaaaa aagagtatga agaagcaatt ttgcataaat tgaaagaaaa aaagatcgat
     7381 ttgatcgtat tagctggata tatgcgaatc attggaccgg tattgctgaa aaattatgat
     7441 aaaagaatca tcaatatcca tccgtctctt ttacctgcct tccctggttt gcatggcata
     7501 cgtgatgcct ttgaagctgg agtaaaagaa acgggtgtca caattcatta tatcgaccaa
     7561 ggtgtagata ctggaccaat catccggcag gaaaaagtga gaattgaaca ggaggacacg
     7621 ttcgattctt tagaagaaaa aatccataga gtagagcatc gaatctatcc agaagtgatt
     7681 agtgaaatta ttgaaaatgg aggctatctg aaatgacaag agcattgatc agtgtatcag
     7741 ataaaactgg gattgtagca ttcgcccaag gtttgattga acaaggagta gaaatcattt
     7801 caacaggagg aacaaagcat gcgttggata aagctgggat caaaacgctt tcgatcgaag
     7861 aagtgacagg gtttcctgaa atgatggatg gccgtgtcaa aacacttcat cctaaaatcc
     7921 atggtggtct tttaggaaga cgcgatctcc ctagccatat ggaggcaatg gaaacggaaa
     7981 atatccaacc aatcgacttt gtttgtgtca atttatatcc tttcaaagaa acgattatga
     8041 aaccagatgt cgaaatagca gaagctattg aaaacattga tatcggtggt cctagtatgc
     8101 tccgtagtgc agcaaaaaac catgaatttg tcacctctgt tgttgatcca tctgactatg
     8161 aagaagtact ttcagaatta cgtcagtatg ggcatacttc actttctttc agacaaaaac
     8221 tagcggcaaa agtctttcgt catactgcgg catatgatgc actgatcgct caatacttaa
     8281 cggattgggt ggaagaaaaa gaaccggaaa aattgacact tacgtatgaa cgaaaacaaa
     8341 cgcttcgtta cggtgaaaat agccatcaag ccgctgcctt ttatcagtcc gctcttctgg
     8401 aaaaatattc gatcgcagca gcaaaacaac tccatgggaa agaactttct tataataata
     8461 tccgagatgc agatgctgcg ctacggatca tgaaggaata tgacgagcca acggtagtcg
     8521 ccttgaaaca catgaatcct tgtggtattg ggacagcatc tacgatttta gaagcgtggg
     8581 aagcagcgta tgaagcagat cctgtttcaa tctttggtgg gatcatcgtt ttgaatcgag
     8641 aagtagatct gccaacagca gaacagatgc ataagctgtt tctagaaatc atcattgccc
     8701 cttcttatac acaagaagct ttggaattac tgcaaaaaaa gaaaaacatc cgattactga
     8761 cagtagactt tgcgcaggaa gaaaatcaaa atcgagaaga aacggtctca gtcttaggtg
     8821 gacttcttgt acaagatcaa gatctggcaa tagaaaatga agaagagtgg aaagtcgtga
     8881 caaaacgtaa gccgactcca gcagaagcaa aagcattagc gtttgcttgg agagctgtca
     8941 aacatgtgaa atctaatgcg atcgtactgg caaacgaacg tcagacagta ggaatcggag
     9001 ccgggcagat gaatcgagtc ggttcagtaa aaattgcgat tgaacaagcg caagagaaaa
     9061 tggaaggtgc agttttagct agcgatgctt attttccaat ggatgattcg gttgaatatg
     9121 cagccaaaca tggtataaaa gcaatcattc agccaggagg aagcatcaaa gaccaagatt
     9181 ctattgatat ggcgaataaa tacgatctag caatggtctt tactgatgtt cggcatttta
     9241 gacattagag aggagtcgga taaatgaaca ttttggtgat cggtgcaggt ggtcgtgaac
     9301 atgcaataag taaaaaactt ttagccagtc cgaaggtgga tacggtgtat tgtgcgccag
     9361 gaaatccggg gatgacaaaa gatggtatca attgtgtcgc tatcagtgag cgagatcatt
     9421 cagcgttaat ccattttgtt aagaaagagg ctattgattg gagtatcgtt ggtcctgaag
     9481 ttcctttgtt aaatgggatc gtcgatgatt ttatggcgga aggattgaaa atcttcggtc
     9541 cgacaaaagc agcagctctg atcgaaggtt cgaaaagttt tgctaaacaa ttaatggata
     9601 cttatcaaat cccgacagct aaatccagaa gttttgaatg ttacgaaaaa gcagcagcgt
     9661 atatcaaaga aaatggtgcg ccaatcgtag tgaaagcgga cggcttagca gctgggaaag
     9721 gtgtagtcgt ggctaccaca gtgaaggaag cgctggatgc ggcagaacaa atgttgaacc
     9781 agcatcgatt tggggatagt agcaaaaaaa tcgtcgtaga agagtttttg gcaggagaag
     9841 aattctccct tttggcgttt gtccgtaata ccaaggtgta tccgatggtc atttcgcaag
     9901 atcataagcg ggcatttgat aacgataaag ggccaaatac aggcggaatg ggtgcttatt
     9961 caccagtacc gcaaatttca aaaaagatga ttgaaaaagc tgtggaagaa gttttaaaac
    10021 cagcggcttt gggaatgaaa gaactaggac gctctttcac gggtgtttta tatgcgggtt
    10081 tgattgctac gaaggaagga ccaaaagtga tcgaattcaa tgcgcgtttc ggtgatcctg
    10141 aaacgcaagt cgttctttct cggttgaaga gtgactttgc gcaagtaatc gatgatttat
    10201 tagagaatcg tacagtagag ttaaagtggc agcaagaagg atacaatgta ggcgttgtgg
    10261 ttgcagctgc cggttacccc gaagaatatg agacaggaat ggttctacca gattttctgg
    10321 aagaagagct ttctgtttac tatgctggag tttcctcaaa taacggcaaa ctagttggag
    10381 caggaggacg tctttattta gtagaagcat acggtgagac gatcaaagaa gcacagaaaa
    10441 aaatttacac cgcgttaatg gataaaacga cagatggaac attttatcgt acagatattg
    10501 gagaaaaagc tgccaatagc gaactgatcg tgaagtaaat cagctgcttc catttataaa
    10561 aaatacaaca aacataatcg gaagcgccga ttttagtgaa gccttttcat aaagagtgtg
    10621 gtacactttt gttgtgtata taaataagga ggagttcaga tgaaaaaaat tcaattaggt
    10681 acttctgatc agaaagcagc tgcagtgatc ttaggctgta tgcgtatcaa caatgcggaa
    10741 gatccagtaa aagtgattga gacagcttat gaaaacggca ttgatttttt tgaccatgca
    10801 gatatttatg gaaacggtga atgtgaagaa atctttgcag atgctctagc aaaaacatca
    10861 atcaaacgag aagatctttt tattcaaaca aaatgtggaa tcgttccagg tgtgatgttt
    10921 gatttttcta aaaaacatat cattgaatct gtagaaaaaa gtttgacccg tctgaaaatg
    10981 gattatgtgg atgctttact tcttcatcgt ccagatacat tggtagaacc agaggaagta
    11041 gctgaagcgt ttgatgaatt ggaacggtca ggaaaagttc gttattttgg cgtcagcaat
    11101 caaaaaccaa tgcaaatcga attgctgaaa aaatatgttc gtcaaccatt agtagctaat
    11161 cagctgcaat ttggcttgaa acatactgga atgatcgatc aagggattca tgtcaatatg
    11221 acagatgaag caagtatcga tcatgacggt agtgtacttg attattcccg attgcatgat
    11281 atgacgatcc aagcatggtc accataccag tatggatttt ttgaaggtgt atttatcggg
    11341 aacgaaaaat tccctgaatt aaaccaaaca ttagaagaac tagcagctaa atatcaaacg
    11401 acaccaactg gcttggcttc tgcttggatt ttacgccatc cagccaatat gcaagtgatc
    11461 gccggtacga tgaacgtagg gcgaatcaag gaaatcgctc aagcttcaga aattaatatg
    11521 tctcgggaag attggtacga attgtaccgt gctgctggaa acattttacc ttaaagattg
    11581 tcataagcag gtcaaaaggg ctataaatta aaaagacaga ataacttgaa agctgttttc
    11641 agcttcgaga tattctgtct ttttttattg caaatggaaa gagtatcatt gtacggattt
    11701 cgtttattag ttatttttgt ttttaaggaa aagctgtgtc cgatattctt ttggagaaat
    11761 cccttgtttt ttcttaaata aataactgaa atagttaggg tcattataac caatttcaaa
    11821 agcaatatct gaaatacgat agtctgattg ctgcaataat ttttttgcta attcgattct
    11881 ttgttctgtc agataatcga tgaatgtttg gttaaacgat tgagaaaaaa tcgtactgaa
    11941 atgagaggga cttaatgcaa cttgttgagc gacccaagtt aaggacatat ctggatcggt
    12001 aaaattttct ttgataaaat ccaatgcatg gttcaaaatt ggctgatatt tgttccttga
    12061 aggctgtgag ggcagagcag ttaagaaaga aatgaacata taaactgtcg aacggtaaag
    12121 cgagtcgtcg gcgctgattg ctaagcgttg actggtggat gtgcaatgaa ccatttcttg
    12181 cgggattttc ttttctttca ggcagacatg ctggagtagc ttagtcaaga caaataaacg
    12241 atataatcgt gttcgagttg gtgtgccttg tggtttcgtc aagtgttcga tgtacttaga
    12301 tacttcgttt ttcgataatg aagacaaatc aagtgagagg tcaaagtaaa agacagaatc
    12361 aactggaagt ttcgcttctt gaatcaaatc ctcatagctg ataatttgtt ctttaaggga
    12421 actggcggtt tcaagtatca tctgcgtgat ctcaaaagat gcaggtaatt cgctgattct
    12481 ttctgcgaca ggaccaatgg cgacagaaaa attatttttt tgtccctttt ctaattcatg
    12541 gaccaacgtt tgggctacct gataactggt ctcgatcaca ttttcttcaa gagaatcaac
    12601 tattaaaaat ttgatgaatc gagaggaaac agcagagaag atcacttgtt gattctccct
    12661 aaataaaaac ttcaaataat cactgagatg agcgtaatct tcaaagtctg tactgacttg
    12721 gtttgctgct aataatacgg tcattttttt ccctgctaaa gagcgattga aagattcagc
    12781 aagtttcaat gtttcactga tcgtaagtga gcctttgaac aaaccgttca agaaatgatt
    12841 ttttttcaat tcgaaaacaa gatcagaaga agtgtgcgtt tctttttgct gcaaatctaa
    12901 agcagttact gctttttcta ttgcttgttt caattcgcta cttttaatcg gtttaagcag
    12961 ataatcatct gcctgtacct ggattgctcc tttcatataa tcgaaatcgt cgaatccact
    13021 aataaatatg agacgagtcc aaggaagtag tttccttgct tcttttgaaa aagtcaaccc
    13081 gtccatgaaa ggcatttgga tatcagtcag aatgatgtcg ggctgtaagt cgataattga
    13141 agacagtgcc atctcaccat ctccagcttc gccgacataa gtgattggat aataagaacc
    13201 aaggacagtt atttgttccc gcaagttatt gcgaatgagg tattcgtctt cgatgataaa
    13261 aactttatac atgtttgttt cctccaattg ttttgggaga tagagggatc atcagtgtga
    13321 cagttgttcc ttctcggtat ttgctgtcaa tcgtgatagg tttttgatca tttccgtaat
    13381 aaagaaggag acgcttgttt acgttgtaaa gtccgtagcc gatactgaaa tctgaatcga
    13441 tccctttggc taactcttta cgtatttctg ccagtttttc tgcagggatg ccaatcccgt
    13501 tgtctataac tttgaattgg atcatctcat caattttgca tgtggtaata cgaataaatc
    13561 ctttgtgacg gacgtacttc gttccatggt atacagcatt ttcaatcaat ggctgcaaga
    13621 tcatttttaa aatagaaaca ggaaaaagtg tttctggtat atcgatctta tagtcaagca
    13681 tatggccgta tcttattttt aagatgacta gataatcatt gatatggcta atttcttttt
    13741 caagaggaat ccagtcttgt cctttgctta aagacgtacg aaaaaagccg gaaagtgcat
    13801 gggtcatagt cagagcttct tcaaagcagt cttgttcgat caaagaaata atggcatcca
    13861 aactgttata aataaaatgg ggagtaatct gagcttgcaa tacacgaact tcactttgtg
    13921 ctaaatggta ttgtttcaaa gcgttctccc gtaaagactg gtttagatct tccgccattt
    13981 tattcatgct agcggtaagt gtttgtaatt ccagtgtttc cggcagggtt aaacgaaagc
    14041 caaggttccc tgaagaaagt tgttctgaca tctcgatcag ctgattgatc ggttcttgga
    14101 cctttctctc taaaaagcga cgattctttt tcgcatagaa aaaaatggta ctaagaactc
    14161 caagttccac tattgttaat agaatgagcg agcggacaag tgtcgtattt tttttgcttg
    14221 ctaagtcgat ctccacacga acaaaatctt gtaagatatc tgacagcagt tgagtgacag
    14281 aatctacctg attgatgatc tcttcattgg tatccataaa atcttttgcc aagatattat
    14341 tgatcagctc gttttgataa tcttccagtg tatcgatcgt acgtagcgat acatctaacg
    14401 tactaatttc tttaagtgta tttgtattat ttttgatctc tcgaatatca ttcctaagtt
    14461 cttctaggat attttcctca ttgaactcat ctacggttac ttggccagaa atcaagtccc
    14521 acatactttc caaaactttt tgatcaacct tcaaagcaat tgcatctgct ttttggatat
    14581 ttgcgatcgt ctgttgataa atcaaaagct gttgcgaata taacagtatg ctcagtagca
    14641 aagggataac agcaaataga agcatggctt tgtttgcttg ggcaaaaatc tgttttatgc
    14701 ttaaattttt tgtcatgata cttctccagt caataatttc tggttgggat gttagctata
    14761 ttctgctggg aaaagacagt ctcggaaata aaaatatctt taggtaatgt ttttcctgtt
    14821 tgaatatttc caaaataacg agtaacggta ttggctacat accagccgac atcaggttta
    14881 cactcgacta cacaattgac gattcctgag cgtagcttct cgatcatatc ttcttgtcca
    14941 tcaatagtta caatgatcaa atcttctcca ggtttgattg atgtttcttt tatcgcagct
    15001 aaagcaccgt gagtcatttc atcactatgg ctgtataata catcgatttc ggataaatca
    15061 tttgtttcta aatatcgttt catctggtct tttcctttca tccgaataaa atcaccgaca
    15121 attcggtgaa caatagtcat cggaggttta tggtcgatgg ttccatcttt ttttagggtt
    15181 ggtttacgat tgattgattc caaaaatcct tcggagcgta gcttggtcgg tgtggagttc
    15241 tctgaaccag caagttctag gattctgatt tcctgtttct ttgaatttgt gaagtgattg
    15301 ctgacaaata aacccgcccg atttccttct gctttgaaac tggggccaat gtgggtgacg
    15361 aaaagctcgg gatcattcgt ttgaatatgt ctgtcgacaa gtatgacagg gatccctgct
    15421 cgctttgctt cttttaatac agagtcccac ccggattctt gcaaaggagt aaaaatgatc
    15481 atatccactt tataggcaat gaacgtccgt atatcttgga tttgccgttc ctgattcatg
    15541 tagccatttc ggtagagaac ttggtaatct tctttttcaa gcgcagtgat aattgattca
    15601 gtatgctttt tccgccagct actctccgtt cctgattgcg aaaaaccaac gactagtggg
    15661 tcaggtgctt cctttgtatt aggtgtacac cccatcattt ggtaagcgat tacaacaagg
    15721 gctaaaaaaa ataaaacacg tttcacttta aatcactcca tctggatttg ttagtactat
    15781 cttatcagat aaaagggaaa atcaaagtca aaaggaatca atcgaaaaaa atccaagaaa
    15841 cttaaaaaaa tccaagacaa aaaaagtaca cctaaaaaat ttaaagtaaa tcccataaaa
    15901 aaatcaatgt taacgctttc tttattagct atactcggtg tatcaattga aatgggggat
    15961 aaaaaatgaa aaacaaattt agaaagattg ttgggactat cgctattttg accgcaagca
    16021 ttctattaag tgcgtgtggc aattcaggat ctgcagatga tagtacgggg tatgtaggaa
    16081 tcgctatgcc gaccaaatca gcagaaagat ggatcgctga tgggaacaac atggtctcgg
    16141 aattagaaaa actgggttat aaaacagatc ttcaatatgg agaagataaa gtagaaaatc
    16201 aagtagcaca aatagaaaat atgattacaa aaggggtaga tacacttgtg attgcttcta
    16261 tcgatggttc ggctttaact gatgtgttag ctaaagcaaa agaagcagat atcaaggtga
    16321 tcgcctatga tcgtttactg atgaattcag aaaatgtcga ttattacgcg acttttgata
    16381 attttggagt aggtgtatcg caagcagctt atattgaaga gcacttagga ttgaaagaag
    16441 gaaaaggacc attcacgatt gaattatttg gtggctcgcc tgacgacaac aacgcactaa
    16501 tcaattacaa cggagtgatg tctgttttac aaccatatat ggacaacggt cagttggtcg
    16561 tgccatctgg acagacgagt ttcagtcaaa tcgctacgct tcgctgggat ggttctacgg
    16621 cgcaagcaag gatggataat ctgttaagcg caaattatac tgaccaaaca ttggatgctg
    16681 ttttgtcgcc atatgatcca ataagtttag gaatcatttc gtcattaaaa ggcgtggggt
    16741 atgggagtga aagtaaacct ttacctgtga ttactggaca agatgcgaca gttgctggcg
    16801 ttaaatcgat cattgccggg gaacaaacac aaacgatctt taaagacaca cgtatcttag
    16861 caaaaaatac gattgaaatg atcaaagcaa tcagtgatgg agaagaggtt ccggtcaatg
    16921 atactgaaac ttatgataat ggggtgaaaa ctgtccctac gtatttagca aatacagtat
    16981 ctgtcgataa agataattat caagcagagc tgatcgacac cgattattat aaagaatccg
    17041 atctgaaaaa ttaagaggaa ccaaacaagg aactaaagag atctaagtca gagagaggat
    17101 aagaattatg gcggattgta ttttaaaaat ggcagatatc accaaaaaat tttctggaat
    17161 ccgagcgtta gattgcgtga atctgatgat tgaacgtggg gaaatccatg cattgtgcgg
    17221 agaaaacgga gcgggaaaat caacattgat gaatgtcttg agcggcttgt atccatatgg
    17281 ctcctatgac ggggaaatct tttatgatgg aaagctgtgt caatttaaag atttgaaaga
    17341 tagtgaagaa aaaggcatcg tcatcattca tcaagaatta gcactaagtc cttatctttc
    17401 aataaaagag aatatttttc tcggaaatga acaagcagaa agaggcgtga ttgattggga
    17461 actgacagaa aagaaaacat atgaactgct gaataaagtc ggtttgtcta tcgacccgaa
    17521 tcttctagta tcccagattg gcgtagggca acagcaacta gttgaaatag ctaaagcatt
    17581 atcaaaatcc gtccgtctgt tgattttgga tgagcctacc gctgcattga atgaagaaga
    17641 aagcgcgaat ttgctgagat tgatccgaga gttgaaagag caaggtgtaa cctccatcat
    17701 tatttcacat aagctgaatg aaatcgtgga tatcgcagat cgaatcacca ttttacggga
    17761 tggacagacg attgagacac tagaaaatga aatgatcagc gaagagcata ttattcgcgg
    17821 aatggtgggc agagatttag ttgatcgtta tcctgaaaga aaaccggata ttggagaagt
    17881 ttattttaaa gtagaagact ggacggtcta tcaccctctt gatcacgagc gaatcataaa
    17941 cgaccacatc aacttgcatt tgaaaaaagg agagattgta ggaatagctg gactgatggg
    18001 agcgggcaga actgaattcg ctatgagtct atttggacat tcttatggaa gcaagatatc
    18061 cggacgtata ttaaaggaag gggcagagat atcagttaag accgttcctt cagccattgc
    18121 aaacggactc gcttatgtct cggaggaccg aaaatcttta ggactgaatc tgctgatgga
    18181 tattcgggaa aacgtgacgc tgagcagttt ggataaaata agtcaaaaag gagtattaga
    18241 taaagaaaaa gaagtaactg aggcagaaaa tttccggaaa aagatgcgta taaaaacaaa
    18301 ctccatccat caaattgtca gtagtcttag tggtgggaat caacaaaaag tcgttttatc
    18361 caagtggctg atgacacaac ccgatattct ttttttggat gagccaaccc gtgggataga
    18421 tgttggggca aaatatgaga tctacacgat tatcgaagaa atggcagcaa atggcaaagc
    18481 tgtctgtctt atctcttctg aacttcctga aatattaggg atgtgtgatc gaatctatac
    18541 gatgaacgaa ggacgtatta caggagaagt ctcgcgagaa gatgcagatc aggaagtctt
    18601 gatgaaatta atgacgaaag aagaggtggg ttaagttgga acaggcaaaa aatcttacgg
    18661 ataaaaaaga gaaaaaacta aatttgaaaa gtagagcagc tgatcttttt ggtcgctaca
    18721 gcatggtgat cattttagcg ggactactta ttgcgtttca attgatgacg gatggtattt
    18781 tctggcgtcc attgaatata actaaccttg ttctgcaaaa tagccatata ttagtactag
    18841 ctgcagggat gttattagtt gtgctcttag gtcatgtgga tttgtcggta gggtcagtga
    18901 tggcgtttgt tggtgcaatt gcgggcatga tgatggtcaa tcgccaaatg aacccgtgga
    18961 tgacagttat cgcatgtctt gcagtaggcg ggctgatcgg cgcatggcaa ggtttttggg
    19021 tagcttatgc agggataccg gcgtttatcg tgactttagc aggattgctg atgtttcgtg
    19081 gactgacaca agttgttcta ggaggccaat ctctagcacc ttttccagct gttttccaaa
    19141 aaatgtctac gggttattta ccagacttaa gcgaaggaag cagccttcac ttcttgacat
    19201 tgattttagg aatgatcatc acgatcgtgt tagttgttgg tcaatggcga acaagaaatc
    19261 gtcggaaaaa tcatttattt gaagtggaat ctccaacagc tttcttggta aaggcggtat
    19321 ttacagcagt cgttgtacta ggaataactt atatctttgc ctcttatcaa gggtatccga
    19381 ttattttgat cattcttggt ttgatcgttg cagcatatgg gtttttgaca aataaaacag
    19441 tagcaggtcg acagatttat gcgacgggcg gaaatcgaaa agcggctgaa ctatcaggga
    19501 tcaaaacaaa gcgaatcacg ttctgggtat tcgtcaacat gggagtcatg gcagctttag
    19561 ctggattagt tttagctgct cgattgaatg cggcaacacc tcaagcaggt acatcgatgg
    19621 aactggatgc aatggcggca gtatattttg gtggtgcttc gacttccggc ggcattggaa
    19681 caatcatggg tgcgattgtc ggtggcttgg tcatgggtgt attgaacaat ggcatgtcga
    19741 ttttaggcgt cggggtagac tggcagcagg caatcaaagg attgatcttg cttttagccg
    19801 ttgtgctaga cttgtataat aagaaaaaac gaacaacgta ggagaacgcc ggttattcag
    19861 aaaaaagact gtgacaagac atttgtcaca gtcttttttt cgctaaaagc gaacattcat
    19921 tgtttcgttt gtatagacta aaaataatat atgttttttt accattcgta taaattctct
    19981 ttttgctctt gatttttttg cttaattgag ttaaattaca tagggcgcta aaaaaagcct
    20041 tgattaaatt aataatgttc gtgttttgct ggatgtgaac atcaggagga taatgtaatg
    20101 aaagtatttg attacgaaga tattcaatta attcctaata aatgtatcgt aaatagccgt
    20161 tctgaatgtg atacaacggt cacattaggt aaacatacat tcaaaatgcc agtagtgcct
    20221 gccaacatgc agacgattat tgatgaaaca atcgcagaat tcttagcgga aaatggttat
    20281 ttctatatca tgcatcggtt tgatgaagca gctcgaattc cgtttatcaa aaaaatgaaa
    20341 aagcgtggat tgattacctc gatcagtgtt ggcgtcaaga aagaggaata ttcctttata
    20401 gagaagttgg cagaagaatc gctaaatcct gattatatca ctatcgacat cgcgcatgga
    20461 catgctaact cagttattga tatgattcag catattaaaa aatatttgcc tgaaactttt
    20521 gtgattgccg gtaatgttgg tacaccggaa gccgtccgtg aattggaaaa tgcgggcgca
    20581 gatgcaacaa aagtcgggat tggtccagga aaagtatgta ttacaaaaat caagacaggc
    20641 tttgggactg gaggctggca actggcagct cttagatggt gtgcgaaagc agctcgcaag
    20701 ccgatcatcg ctgacggtgg gatcagaaca catggcgata ttgcaaaatc tgtccgtttt
    20761 ggtgcgacaa tggtcatgat tggttcattg tttgccggtc acgaggaatc tcctggcgaa
    20821 acaaaagtcg aaaatggaat cgtgtataaa gaatactttg gttctgcttc agaattccaa
    20881 aaaggcgaaa aacgaaatgt tgaaggaaag aaaatctgga tccaacacaa aggatctttg
    20941 aaagatacac tagtggaaat gcaacaagac cttcaatcat ctatttctta tgctggagga
    21001 agagatctgg aagccattcg aaaagttgac tatgtcatcg tgaaaaattc gatttttaat
    21061 ggagacacaa tctaaaaaat aaataaaata ttaggatgtt gtgaaaaagt tgtcctgcat
    21121 taagtaataa gaacagccaa acaaaaatag ttctttatat gttttgtttg gctggaatta
    21181 ttatcgcaga tacaagcttt tgaacatcat tattcagaat aagggactgt gataagattt
//
LOCUS       DAIGUC010000051        21101 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.051, whole genome shotgun sequence.
ACCESSION   DAIGUC010000051 DAIGUC010000000
VERSION     DAIGUC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.051"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="NOB46_002084"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="NOB46_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HCI1059009.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="NOB46_002085"
     CDS             complement(2020..2922)
                     /locus_tag="NOB46_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1059010.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="NOB46_002086"
     CDS             complement(2919..3611)
                     /locus_tag="NOB46_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HCI1059011.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="NOB46_002087"
     CDS             complement(3654..4295)
                     /locus_tag="NOB46_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI1059012.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="NOB46_002088"
     CDS             complement(4333..4647)
                     /locus_tag="NOB46_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059013.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="NOB46_002089"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="NOB46_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="NOB46_002090"
     CDS             complement(5984..6916)
                     /locus_tag="NOB46_002090"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCI1059014.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="NOB46_002091"
     CDS             complement(6913..7689)
                     /locus_tag="NOB46_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCI1059015.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="NOB46_002092"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="NOB46_002092"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCI1059016.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="NOB46_002093"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="NOB46_002093"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCI1059017.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="NOB46_002094"
     CDS             complement(12014..13294)
                     /locus_tag="NOB46_002094"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCI1059018.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="NOB46_002095"
     CDS             complement(13313..14239)
                     /locus_tag="NOB46_002095"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HCI1059019.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="NOB46_002096"
     CDS             complement(14252..15535)
                     /locus_tag="NOB46_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCI1059020.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="NOB46_002097"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="NOB46_002097"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCI1059021.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="NOB46_002098"
     CDS             complement(16323..17234)
                     /locus_tag="NOB46_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI1059022.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="NOB46_002099"
     CDS             complement(17231..17695)
                     /locus_tag="NOB46_002099"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCI1059023.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="NOB46_002100"
     CDS             complement(17700..18398)
                     /locus_tag="NOB46_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1059024.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="NOB46_002101"
     CDS             complement(18385..18771)
                     /locus_tag="NOB46_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059025.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="NOB46_002102"
     CDS             complement(18918..20588)
                     /locus_tag="NOB46_002102"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCI1059026.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="NOB46_002103"
     CDS             20771..21004
                     /locus_tag="NOB46_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HCI1059027.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
BASE COUNT         5902 a         4746 c         3743 g         6710 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaacg atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa a
//
LOCUS       DAIGUC010000052        20111 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.052, whole genome shotgun sequence.
ACCESSION   DAIGUC010000052 DAIGUC010000000
VERSION     DAIGUC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.052"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            4..2376
                     /locus_tag="NOB46_002104"
     CDS             4..2376
                     /locus_tag="NOB46_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059028.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAESGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVTKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKTGQTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFSLGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="NOB46_002105"
     CDS             2437..3897
                     /locus_tag="NOB46_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCI1059029.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERSNGTYDFDRFYQGKGDINAQILFSYKAEQYYKGYKKHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /locus_tag="NOB46_002106"
     CDS             3908..6112
                     /locus_tag="NOB46_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCI1059030.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSLLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESYRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYHKAAACTSEACDFRLWTTIAKKKLTATQLKEII
                     QNGRTSQPVKGLKGQKGSFEATIVLKEDFTTSFEFSEKKKTNYKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="NOB46_002107"
     CDS             6128..6277
                     /locus_tag="NOB46_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059031.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6358..6954
                     /locus_tag="NOB46_002108"
     CDS             6358..6954
                     /locus_tag="NOB46_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HCI1059032.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYSKAEWYELGKIEIKSRYGNPVIAYDPERTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTIRSYIMALN"
     gene            6967..7866
                     /locus_tag="NOB46_002109"
     CDS             6967..7866
                     /locus_tag="NOB46_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HCI1059033.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFENRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYEETMDSISNLMEKVI
                     HVEEKERKIAYQRHQQMNREMER"
     gene            7869..8354
                     /gene="ssb"
                     /locus_tag="NOB46_002110"
     CDS             7869..8354
                     /gene="ssb"
                     /locus_tag="NOB46_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI1059034.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGILIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            8720..8980
                     /locus_tag="NOB46_002111"
     CDS             8720..8980
                     /locus_tag="NOB46_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059035.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9427..9633
                     /locus_tag="NOB46_002112"
     CDS             9427..9633
                     /locus_tag="NOB46_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCI1059036.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9633..9857
                     /locus_tag="NOB46_002113"
     CDS             9633..9857
                     /locus_tag="NOB46_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059037.1"
                     /translation="MKTQHKLLNVKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFE
                     DLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            9872..10309
                     /locus_tag="NOB46_002114"
     CDS             9872..10309
                     /locus_tag="NOB46_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059038.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEAGVKPSTIKPSEYQALE
                     LTYGKFIETKKAKTVSSEWLDYFENVNKYGACYIMKKEDNENE"
     gene            10302..11009
                     /locus_tag="NOB46_002115"
     CDS             10302..11009
                     /locus_tag="NOB46_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059039.1"
                     /translation="MSNVVYQLTVEDVSHFLTNKEHLNEVVRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDCKRMPYQRFERKKGQ"
     gene            11390..11569
                     /locus_tag="NOB46_002116"
     CDS             11390..11569
                     /locus_tag="NOB46_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059040.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQELKQKYGKSESRIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            11662..11847
                     /locus_tag="NOB46_002117"
     CDS             11662..11847
                     /locus_tag="NOB46_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HCI1059041.1"
                     /translation="MPLTGKEMLKLLKKNGWVERRQEGSHHHLYKDGVRITVPVHANQ
                     DLGRGLEQKILKDAGLK"
     gene            11881..12312
                     /locus_tag="NOB46_002118"
     CDS             11881..12312
                     /locus_tag="NOB46_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCI1059042.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNLLRSGRNN"
     gene            13249..14523
                     /locus_tag="NOB46_002119"
     CDS             13249..14523
                     /locus_tag="NOB46_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1059043.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLAVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
     gene            14577..16004
                     /locus_tag="NOB46_002120"
     CDS             14577..16004
                     /locus_tag="NOB46_002120"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI1059044.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPEDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDHLYMKPVRELEQLRVG
                     SGVETKVNLAGEIIIAQDASFKEALIDVLLTKSKNQEIKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            16017..16889
                     /locus_tag="NOB46_002121"
     CDS             16017..16889
                     /locus_tag="NOB46_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1059045.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNELLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            16984..17979
                     /locus_tag="NOB46_002122"
     CDS             16984..17979
                     /locus_tag="NOB46_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1059046.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKDN"
     gene            complement(18584..18691)
                     /locus_tag="NOB46_002123"
                     /pseudo
     CDS             complement(18584..18691)
                     /locus_tag="NOB46_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            18807..>20111
                     /locus_tag="NOB46_002124"
     CDS             18807..>20111
                     /locus_tag="NOB46_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1059047.1"
                     /translation="MIIKNLGNVKSIDIHVKDLLIFTGKNNTGKTYTSYILYGILSEL
                     FGARFFNYFSHTEIEPHLQNSLNILLVSKDSIRKKFNNDAKKFLEENLKKIAVRNFKV
                     SENNFKNLSFTISDSEISELTGDIFNYEIKRYSISGIVITIQNVGEKLKISFEPTDSF
                     QYLSKDIEIEDIYKILAQELSKNVISLPKVFYFPAERTGINVFKNELNESRLKTYDTL
                     LNTVQFTNLTNQKKKAALKYDLLKKNIELLMETTDNSSYPKPISDYINYLNNMKNRYE
                     QKNVNNIASYIRDEIIMGKYEIDEKDNSVSFRQKFGKNRYRKERIPFHVVSSSIKSLY
                     GLDYYLENSSKEGDYLIIDEPELSLHPENQVKLAKVITDIVESKIKLITSTHSDLFVR
                     ELTNIVIENKLNSKNNKKNKLSDKNIGIYNFVGNNDINELEKI"
BASE COUNT         7344 a         3125 c         4009 g         5633 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgca
      661 ccaactgatt ctctgaagga gaaagaaaaa gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agagttgatc
      781 gatcaactta aaacgttgga taaccaatac gctgcagaat caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgttacga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgag
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcatgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatt gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacaa ttgaagcctg aagactatcc gaaaatcttc
     1501 ccgaaccgcg tctttgattt tcaattggat aaaacagggc agacagaact tcaagttggg
     1561 attcaagcgg tagccaaaaa tattggaatt caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtacgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagaacaaa agaatattgt tcctgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaattttc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaaca tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaatg agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagttaaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtttcgat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagttgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aagtcattta tgaagaagtc gcaaaagaag aaaagatcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaatt ggtttccgct
     3541 cacaaagtaa atgcgtcttt tggtcagcag ctttctgtta acgattcaat agaagctatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagcttgtga acgctcgaat
     3661 ggtacgtacg attttgatcg tttttatcaa ggaaaagggg atattaatgc tcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa agcatgaaca tgaatttgta
     3781 cctgaagtga aaaaggattg gaacgatcaa ttgaagcatg agatccagca acaagaaatt
     3841 agaaagcaaa aacgtgcgat gttgtttcaa caaggcagac aacaagaaag ggagtgagat
     3901 cgtcacgatg aaaactgtca ttttagcaga aaaaccgtca caagcgaagg cttatgccga
     3961 tagcttttct aaagccaccc gaaaagacgg gtattttgag atccaagatc gattgtttcc
     4021 tggtgaaact gtgattacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacattta cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaac gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgc gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagcag gcgccgatca tggaaagata tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagatg cagaagagac
     4381 ctacccaaaa tttgaagaag cacaagcacg ccagatcgcc gattggttga tcggcatgaa
     4441 cggtagccta ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gtttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttacaggaaa agattagaaa
     4561 cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggtacg atccaccaag ttgaaaccga
     4741 gaaaaaaagt gcggcaagtc cacgtctttt ttctctatcc agccttcaat ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt tgtatgaagg
     4861 aaaatatcta agctatccgc gaacggatac cccttatatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttaaaa gccgaagcga ttccgactcc
     4981 tattcataca ccgaatagtc ggtatgtgaa taataagaaa gtccaggaac attacgcgat
     5041 cattcctaca aaaacggtta tgacagcagc ggcttttgaa caactaagtc cactgcagca
     5101 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     5161 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ctaaagacag tcggaaaagt
     5221 accagtagat ctaggttgga aaaagctgtt tggcaaagag agctacagaa aagaaaagga
     5281 agaagaaccg ctacttccta aagtgacaaa aggagaagcg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaacgaagc caccacaacc ttataccgaa ggtacgttga tcacagcgat
     5401 gaaaacagct ggaaaaaccg tggatagcga agaagcacaa tccatattga aagaagtaga
     5461 aggaatcggt acagaagcaa cacgagcaaa tattattgaa actttgaaac aaaaggaata
     5521 tatcaaggta gaaaaaaata agcttgtggt gacaaataaa gggattttac tttgccaagc
     5581 cgtggaaaaa gagccgctgc taacaagtgc cgaaatgacc gccaaatggg aaagttactt
     5641 attaaagatt ggtgagcaga aaggaacaca agctactttc ttagctaata tccaaaaatt
     5701 tgtctctcac ttgttggaag tcgtaccagg acaaatccaa tccactgatt ttggatcgac
     5761 gttacaagag gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt tagggatttg
     5821 tccaaaatgc caggaacaag aagttttact ctatcataag gcggccgcat gtacgtctga
     5881 agcttgtgat tttagattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggaaatc attcaaaatg gccgaacaag ccagccagtg aaaggattaa aaggtcaaaa
     6001 gggttcgttt gaagcaacga ttgttctaaa agaagacttc acaacgagct ttgaattttc
     6061 tgaaaagaaa aaaacgaact ataagaaaag aacacgccgc actacaaaat aatggagggg
     6121 ttatcttatg cgaaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagcaaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa ttgaattaga tcgataaaat cttcctggct attgtatacg
     6301 cataaactta tgttatacta tatttataag tttatacgta tacaaaggag ggagaaaatg
     6361 acaaaagcaa tggtttacaa gctgctagaa gaatttaacg gaactttggc tttgaaggat
     6421 gccaaaaaag cgggcatttc tcctgtaacg atcaaacgta tggtagatcg tggagagctg
     6481 gatcgtgagt atccaggttt tttcacctta cctggtcaat ttcctgatga attgtttatg
     6541 gcacaaaaga aatatgagcg cggcattatt tcgcatatca ccgcgttgga tttatatgat
     6601 ttaacggata tgatccctag acagatcgat ctaaccgtac cttacggtta tcacgtttct
     6661 gaaaaggggt tgaaagaatt cgcagttgag ttacactatt caaaagcgga atggtatgaa
     6721 ttaggtaaga tcgaaataaa gagtcgttat gggaatcctg ttatagctta tgatccagaa
     6781 agaaccttgt gtgacatttg gaatccctgg tacaacgttg aggatgaaat caaagtaaaa
     6841 gcaatcaaaa actacatgga gtcggacaga aaaaatctta gaaaattgaa tgagtatcga
     6901 cgaattttgc ctacagacaa aacgatacgc tcttatatta tggctttaaa ttaaaggaga
     6961 agacacatga cacctacgca attaaaagca aaagtgaaga atatttccag agaaaaagaa
     7021 gttgatccgc agcttgtttt aagacatttt atgatggaaa aattcttgga aaaaatctca
     7081 gagtctcctt atcgtgaaaa ttttgtgtta aaaggcggct tcttaattgg ctcaaagtat
     7141 ggcattgaaa atcgaacaac aaaagacatt gatacgactt tacgggaaat gaaagtaacc
     7201 aaagaaacat tgacaacggt tctaaacgat attttttcaa cgccgacgaa agaaggcatt
     7261 caatttgaga ttcaaggaat gaaagaaaca agggaagctg attattatcc agggtttagc
     7321 ttacgtgtac tggcacattt ggaaaacatg cggccagatt ttaaggtaga cgtgacgaca
     7381 ggtgactcga tctatcctgc aacgatcact cacagtcata aattgatgtt tgaaaatcga
     7441 acgattcctt tggaatctta tcctacagaa caaattattg ccgaaaaatt aagtgcaacc
     7501 tttgattttt taacagataa ttcgagagga aaagattttt atgatctcta tactattcct
     7561 aaaatggaaa agatcgatga gaagaccttg aaagatagtg tgagaaatac atttacacgt
     7621 cgaggaaaaa ctgatccgtt aaagatttat tacgaaaagg atatggatgt actgaaaaat
     7681 agtcatgagc taaaagatac ctggaagaaa tatcaaaaaa gcaatcctta tgctgcgtcg
     7741 atcacgtacg aagagacaat ggattcgatt agtaatttga tggaaaaagt gattcacgtc
     7801 gaagaaaaag agcgaaaaat agcttatcaa agacaccaac agatgaacag agaaatggag
     7861 agataaaaat gatcaataat gtaactttag taggacggtt aaccaaagat ccagatttac
     7921 gttataccgc aagtggcaca gcagtggcta cttttaccct agccgttaat cgtaatttca
     7981 cgaatcaaaa cggcaatcga gaagctgatt ttatcaattg cgtgatttgg cgcaaaccag
     8041 cagaaacgat ggcgacatta gctaaaaaag gcatcttgat cggcgttgtc ggacggattc
     8101 aaacacggac ttatgacaac cagcaaggac aacgtgtgta tgtgacagaa gttgtagctg
     8161 ataacttcca actattagaa agcaaagcag cgacagagag ccgtgcgcac gctgatcaat
     8221 cgtccacgag tccaagcacc accacttttg aacaacggga tacagcgacg cctaacaaca
     8281 atggattgaa cgcttcacag aatccatttg gtggacaatc aatcgatatt agcgatgatg
     8341 atctaccgtt ttaagtagca ttttctattg gttgcatttg ctacggttta tgttataatt
     8401 tagtcaacaa aaagaatttt caatctataa ccaaaaacca ctagctggcg ggctagtggt
     8461 tttcttttac gtttctatta taagaattaa cgagtaggct tactgtcttt cttggcaaat
     8521 ttacaatcaa gccatttgca gatatagtgc gcggctactt ctgccatgat tgcaaaaaca
     8581 aaatcaaaaa gaattttcaa acctataacc tcctcccctt gccagattag gccggggtag
     8641 cagacagcaa gactattata gcataattga aatatccaaa tgattggatt tttgctataa
     8701 ttttagcgag gtgattgtga tgaacaaata tgttggtttg cttgataaaa tccgagtaat
     8761 aaaaacgcaa ccgttattgg ttcgctttac tttacaaacg attcatgaat cgattaattg
     8821 tgtagttgca gatattgaaa ttatcgataa attgctaatt atggatgatg gaaaatacaa
     8881 tattgccgtc acaggtcact tcaataaacg aaatcagctg gttattgcta gcatgtatgt
     8941 tagaaatccc gatcatttta cacgatcgat gggcatataa ataaaagaag agttgtagtc
     9001 ctaaatgagg attgcagctc tttttgtttt acatagaaac gggaacagga aaaggcctgt
     9061 ttaggaaggc acaagcgcct tctcaattaa aaaacctttc tctcactcca accgccaccg
     9121 ccgttcgaga agaaaggaag tgaacgctgc acgttcacta agatatggtg tcttgcaaag
     9181 caagacaaaa taggaaaagc ttcctctcac caaaaggttc gttcctgttc gctatctctt
     9241 tattgatttg ccagaccggc aacaagttgc cttttatcac caaaaagcga caaggacaag
     9301 ggtaaatggc acgctgcgcg cccttgtcct tgtcgctttt cgttgattca ttctggccaa
     9361 caaatcaata aagaaagaac taacgaaagg aagtaaaacc tttcctaaga ggaggcagaa
     9421 tcaatcatgc gaaagaaatt tgattattgg ggtgttccct tcagcgaatt attcccaaac
     9481 tatcatgcac cacatactgt cgaatgcgat tgtggagaaa gagcgaaatg tatcaaaagc
     9541 tatcgtttgt atcaatgtcc aacatgcggg aaaaaatata ccttgtctta tggcgattac
     9601 attttgattg atgagaaagg aaagaaacgc tgatgaaaac acaacacaaa ttattgaatg
     9661 taaaagaagt catttctgaa aaagtagcag aagctttact tattccgcgg tactggacga
     9721 tagaaacccc tttagtagag gacgcaccga ctatgctatt tgaagaccta gtgaagattg
     9781 caggatatga actgcattat caagaaaact tggaaactta tgaaaacgaa tattggttaa
     9841 ccaaattaga gaactaaaaa ggagaaaaaa tatggctcag aattactatg acgaatttgt
     9901 caaattacct ttggataaaa tggcacaaaa aatggaggat atgacgttcc tataccatga
     9961 aacacgtgta cccaaaaaac attacaagga aaaattgtca gtcgcagtgg aagaaatgat
    10021 tgaatcaggt gtcgaaatga atctcattgc gacgtactat cgaacattgg aagaactgaa
    10081 aaaacaaaat ggaaaatggt ttttccaagc cttactatgc ttggaagcag gcgtcaaacc
    10141 aagcacaatc aaaccttctg aataccaagc tttagaacta acgtatggaa aatttatcga
    10201 aacgaaaaaa gccaagactg tttcaagtga atggttggac tactttgaaa atgtcaacaa
    10261 gtatggcgca tgttacatca tgaaaaagga ggacaacgaa aatgagtaat gtggtttatc
    10321 aactaacagt ggaagatgtt tctcactttt taacaaacaa agaacatttg aatgaagtag
    10381 tcagacggat tcaaaaagac tttagttgta tggaagaaat gaagtacttt attcaaagag
    10441 tggaagaaca gttgtatatg gaaagcgaaa cgagtcaaac gaaggtcaca gtcagccata
    10501 atcatttaga cgtgtataaa cgtcgtcctg aaacggtaaa aaaaggaaca gagcttctac
    10561 gactagaaac agaaaaatac atcatgaatg tgtacctaga aaggagtgag ctggtcgaaa
    10621 actttgtcag ctacacgatt tgtaggaaac actattactc agaatcagaa tattattcaa
    10681 tttttgagag catggaatta atggaagaag aaatggaaga gctaaacagc aaaaatgcga
    10741 cggtagacga ttattacctt gtatttacta gatttctgac gtgtgggacg gaatctatcg
    10801 tgttaatggg aatggattat gaactcgctg tacccgaagc atttttgagg gaatatgtag
    10861 aagaagtaga taacccaggc gacgactggt acacgacttt aactgatttt ttagatacct
    10921 acacttacga cgatacagaa gaaatccaaa atgagcttga ctgtaaacga atgccatatc
    10981 aacgatttga aaggaaaaaa ggtcaataac catttatacc gaaaagtgag aatgtgtgaa
    11041 ataagaacaa aaaaccttga aattaaggga atggttctta tttcgcacca atcgctccaa
    11101 ccgcccccgc cgctcaggtg gtgcgaaata agcgggcaac gaccgataac ctaagagaaa
    11161 gaaggaaatc catatgaata aaatcattcc tctgttgttc gtactgtttg ttggcgagat
    11221 acttatgcgt catgctgcag ctgtacattt aaacttcgta gtattcttag gaatactggt
    11281 attttgtttg atcttttggc gatttgtatt agcccttgtg agtctactat tcaagatgat
    11341 tgcagccata tttttcatag ggttatttcg atgaaaggag agagtactaa tgccaattgc
    11401 aataggaaat aaacgtttac ccgtgacgtt ggatgaaaag agacaaaaag aattgcagga
    11461 actcaaacag aagtacggca aaagtgaatc caggattatg tgtattgcgt tagatttatt
    11521 gattgcacaa gaaaaagcag ggtttgatgt accagcactc aaaaagtgac gtcacttttc
    11581 atttgaagaa acaaaagtga tagcacttta cgcacgtgtc gatacgtgtt atgattattt
    11641 tgtaaggagg tatagtgcac aatgccactt acgggaaaag aaatgcttaa gttattgaaa
    11701 aaaaatggct gggttgagcg aaggcaagag ggatctcatc atcatcttta taaggatggt
    11761 gttagaatca ctgttcctgt tcatgccaat caagatcttg gccgaggact tgagcaaaaa
    11821 attttaaagg atgcgggatt gaaataatct cgcattcgat taaagaaagg attgactgaa
    11881 atgttaagtg agcctttagc aaaaacctat cctgctattt ttagcccaga agaaggtggt
    11941 gggtacttta ttgaatttcc tgatgttcaa ggtgcttaca caggaattaa cgaagacgat
    12001 atatcttatg gaattgctat ggcacaagag gtgttaggta tggttttagc agattatatt
    12061 gagcatgaag atctacttcc agaaccaaca ccaatcaata agatttctgt tgaagatgat
    12121 tcttttacta ctttaattcg tgtagatgtt gccaaatatt tgaaagacac agaacttgtc
    12181 aaaaaaacct taacaattcc tcaatgggcg gataagctag gcaaaagggc tggcataaat
    12241 ttttcagtcc ttctaacaga atcaattgca gataaagcag ataaccttct tcgttctgga
    12301 agaaataatt agaactcaaa agagtcagaa acttaaaaat ctttggcttc tttttttact
    12361 acaaagatgg cttctttaaa ttatttgcct gattgattta aaaaaattgc gcaaagacta
    12421 cgagctaatt aagttgctcg tggtctttct ttatgaaaac tttttagatc tagataaaaa
    12481 cattgagaca ctttgaaaaa tttttttaat agtaatgggc gcttctatgt caagctgatt
    12541 cttctttcgg taaattaatt ttacttagaa tatcactatc ttgataaaaa atggtgtatt
    12601 cacaaattct ggcataaaaa atacctactt tctagttaag gttcctgaat aagtcgcaat
    12661 ccaattattt ccagctgatt tataactttt taaatataat tttccataat accaataacc
    12721 attacttttt tctgtccaat ttcgttattg agaagatcta gaaggccagc caactttatc
    12781 aaaaatcatc attcctgtca ctcgtatcgt tttagaagct gctcgagtaa gtaatggaga
    12841 aactgttaaa taattttaag taacagttaa gtcgttagtt gggttatcaa tggctattcc
    12901 gtccttatct gaacctcgaa acccaatcat agaaaaagtt ttttgaacaa gttttaacag
    12961 ataaatcaag ttatatacta gaaaattcgt aaaatatatt tttaatgtca taatcgtttg
    13021 atttttctgg attgacattt atttataaaa aatagtgcca ttaaaaaaga aaagtgacac
    13081 accaataaaa gtcatatcct gtgacattat atggcattat ccaaatagaa taaccggttg
    13141 acatgtaagc ggattccttt tataatttta ggagtataag tccttttcta aaaatattaa
    13201 ccggttatca tgaaagggga tacaaatata tcgttggagg ataaaaatat gtcaaaggtt
    13261 aacgtattta aaaatcaatc ctatttacaa agttcagcta cattattact attttttgct
    13321 tcttggggtg tttggtggtc attttttcaa ctttggctaa catctgaatc aaatggttta
    13381 gggttatctg gcagtgctgt aggaacagta ttctcggcaa attcgttagt taccttaatt
    13441 ttgatgttta tttatggaac attacaagat aaattgtata ttaaacgaaa tttattaatt
    13501 tttgcttctg tattagcgac acttgttgga ccatttttta tatggatata cgggccattg
    13561 ctagataaca attttaattt aggcattatt atgggagcac tatttttgtc agctggatat
    13621 ttagcttctg taggagtttt tgaagctgtg tcagaaaggt ttagtcgttt atttggcttt
    13681 gaatatggac aagcaagggc gtggggatca tttggttatg ccttggtagc gcttttggca
    13741 ggatttttat ttgtaaaaaa tcctcattta aacttttggg cgggatcttt ctttggttct
    13801 ttactattgt taaatttatt attttggaac cctaaagttg aacgggaagc aaatcaaaat
    13861 tttaatcaag aacaagctga atcaaatagt attccttctt taaaagaaat gtttgatcta
    13921 atgaaactgc ctcaattatg gacgataatc atctttattg tttttacatg gacattttat
    13981 acggtattcg atcaacaaat gtttccggga ttttatactg gtttgttttc aacatcagct
    14041 aatggtgaaa aaatatatgg gacattgaat gctattcaag tattttgtga agcgttaatg
    14101 atgggaattg ttccaatcat tatgagaaaa ttaggggttc gaaatacttt gttattagct
    14161 gtaaccatta tgtgtgtacg aattggattg tgcgggtttg cctcgacacc attatctgtt
    14221 tcatgcataa aaatgttgca tgctttagaa gtaccattat ttacattacc aatgtttcgc
    14281 tattttacac ttcattttga tacaaagcta tcagcaaccc tctatatgat aggatttcag
    14341 atagctgctc aaattgggca agtgatttta tcaacaccat tgggaatatt aagagacaac
    14401 gttggctatc aaccaacatt taaaattatt tctcttattg tattactagc aggcatatat
    14461 gcattcttta ttcttaaaca agatgataga gatgttcaag gggatccatt tattcgagga
    14521 taatggaaac caacagaata aaaaacaatt ttatctagaa agtgagcgaa tatattatga
    14581 caaaaagagc tatagaatta acaaatacac gttatcgttt gggatatcat gtgtctgcac
    14641 catcaggatg gattaatgat ccaaatggat tttgctattt tgatgggtat tatcatgtgt
    14701 tttatcaaca tcatccatat agtgctgaat ggggaccaat gcactgggca catgctagaa
    14761 gtaaggattt agttcattgg gaatctttac cacttgcttt gactcctgaa gatcaagaag
    14821 atgaaggtgg ttgtttttca ggaagcgcta ttgaaaaaaa tggtgtgttg tatctgttct
    14881 atacaggaca tcactattat ggagacaatg atccagatca tttttggcaa aatcaaaaca
    14941 tggcgtatag tacggatggc attcacttta ctaaatatga aaaaaatcct gtaatagcaa
    15001 aagcaccaga agataacaca catcatttca gagatccaaa agtatggaaa cacgatgaaa
    15061 aatattacat ggttttgggt agtcaagaaa aagatggatt aggtcgtgct attgtttatc
    15121 agtcgttaga tttattaaat tgggattaca ttggaccaat ttctaaagcg aaggaagtac
    15181 ttacagaagg atttatgtgg gaatgcccag acttttttga attaaatgga aaatctattc
    15241 ttttattatc ccctcaggga attgaagcaa atggaaaaga ttatttaaat ctatatgaaa
    15301 caggctactt tatcggtgat tatgattatg agacagcaaa attcattaga ggaaattttt
    15361 atgaattaga taagggacac gatttctatg caacacaaac aactttatct ccagatggta
    15421 gacgtattgt tatggcttgg atggatatgt gggaaagccc tatgcctgaa aaagtagacg
    15481 gatgggcagg agcattaacg cttcctcgag aattagagtt aattggagat catttgtata
    15541 tgaaacctgt gagagaatta gaacaacttc gagttggcag cggcgttgaa acaaaagtta
    15601 atttggcagg agaaataata atcgctcaag atgcttcatt caaagaagct ctaattgatg
    15661 tactattgac taaatcaaaa aatcaagaaa tcaaattttc attaaaaaca aaagatgaag
    15721 agttaattaa tattttttat tctaaggata aaaatgaatg taccttaact cgtaacggca
    15781 aaaatgatcc aaggtatgga accattcaga tgtgtgatag attatcactt cgagtgttta
    15841 tcgataaaag ttcggcagag atttttatta atgatggcga gcttgttttt acagagcgtt
    15901 attatacaga aaatcaacca agtatgcatt tgagtgttag tgaagaagct tttgtctcga
    15961 gtacaattta tcatctaaaa aaagatgcaa tttcttacga gtaaggaggt tttatgatgt
    16021 taattggtag catagaagca ggtgggacta aatttgtatg tgccgtggga gacgaggatt
    16081 accgagtaca agaccaaata atttgtccaa cgaccacccc cagggaaaca ttgaaaaaaa
    16141 ctgttgacta ttttaaacag tttgatataa atgcattagg tattgcatca tttggtccaa
    16201 tagaaattcg aaaaaattca ccaaaatcag gatatattac gtctacacca aaggtgggat
    16261 ggcgaaatgt taatgtgtta ggttatttac aagatgagct gaatgttcca atgtcttgga
    16321 caacggatgt gaacggatca gcttatggag agtacatcat gtccacttta tcgaatgaaa
    16381 aaataaattc attagtttat tacaccgttg gtactggcgt tggtggtgga gctgttgttg
    16441 acggaaaact attaggatcg tttggtcatt cagaaatggg ccatacgttt gtaaaacgcc
    16501 atcctgatga tattgatttt aaaggaattt gtccttatca tggtgattgt ttagaaggct
    16561 tagttgcggg accaacgttt gaagcacgtt ttggaaaaaa gggtgaagac gtttctttaa
    16621 cggatcctat ttgggatgta atggcctatt atctagcaca agctgtgatt caaacaacat
    16681 tgattatacg accggataaa atagtatttg gtggaagcgt agtaaatgaa aaattgttag
    16741 aaaaaattcg tgttaatgtt aatgaattat tggatgatta cgtggaaata ccaccgttaa
    16801 gtaaatatat tacgcgtcct ttaattaaaa ataatggatc ggcaacacta ggaaactttg
    16861 ctttgggctt gaatcaatta caagaataaa acatagaaaa aatatcgatt atcaggtata
    16921 gtagttctat agagttcttt ttttcgatag ttaattattg cattatttag gagagacaag
    16981 agaatgcgcc caaaattaga agatgttgcc aaaagagcaa atgtatcaaa aacaactgtt
    17041 tcacgtgtat taaacaatcg tggctattta agtcaaaaaa cgattgataa tgtttataag
    17101 gctatagaag aactcaatta tcaaccgaac gttgtagcgc gtcaattatt tcaaaagaaa
    17161 actaacattg tcgggttact atttcctaca gtagccaatc ctttttttag tgaactcgtt
    17221 gaggcattgg aaaaaaagtt atatgaaatt ggttataagg tattaatagg caattcgatg
    17281 aataataaag aaaaggaaac aaattattta aatcagttat tgtctgatca agtagatggt
    17341 ttaattgttg gtacacataa ccaagggatt caggaatata aatatcagaa tttaccgatt
    17401 gttgcaattg atcgagtgat gaatgaagat attccagttg ttgaatccga taactacaat
    17461 ggtggaaaac ttgcaaccaa gttattaatt gcacaaggtg caaaaaatat tattcataca
    17521 aacggtccaa ttgacttaca gactccggct aatcgtcgga gactagccta tgaagatact
    17581 atgaaagcat atcagttaat tccacgaact gtgacattag atttcaatat ttcttatgta
    17641 aagaaaaaac agattttttt ccaaatgttt gaggattatc ctaaaataga tggtattttt
    17701 gcttcaaatg acatcgatgc ggccctaata ttacaagtag caaaagaaaa ggggttaaat
    17761 gtaccagctg atttattagt agtcggatat gatggtactt taatgactcg gagtatatta
    17821 ccagatctga caacagtaat acaaccaatt aatgatatag cagacacagc tgttgctatt
    17881 ttgatgaaac gaataaataa agaagaaaca aaaaaggaat atattttacc tgtcacatta
    17941 tggatgggga agacatcagt aaagaaaaag gacaattaaa tttataaaga ctatcaatga
    18001 taatttcatt attaattcgt gatataaaaa gttgttaaat ctcttataat agactatgat
    18061 acaaaatcat gcttttaatc tgtgtagatg ttgccaaata tttgaaagac atagaacttg
    18121 tcagaaaaac cttaacaatt cctcaatggg cggataagct aggcaaaagg gctggcataa
    18181 acttttcagt ccttctaaca gaatcaattg cagataaagc agataacatt cttctttctg
    18241 gaagaaataa ttagaactca aaagggtcag aaacttaaaa gtttttgatc ctttattttc
    18301 aagtctgatt tgacagattt tcggcagctc atttatttat ggtcagaaat agttgctgaa
    18361 attttaatct attagcaaat agtccagaac gtatgaagag gattcggata tcatttgtca
    18421 ttaacaccat aaatatttat aaaattcgtg ttcacctaca attaaattta atatataata
    18481 ttcgttgtaa gggcttataa ttttttgtta atgaacaaga tatgtaattg atagtgtcaa
    18541 tagctattca aaaatgtagg cttttggccc ataaataaca aggttactta tatgataact
    18601 ttttttcttt ataatcttta atccgataga gctttccagt agtttgaata atcttagcgt
    18661 ggtgcactaa tcgattgatt agtgcatttg tgttcagtcc attgagacat aatagtggat
    18721 agttttactg agaaaattga taaaaaatag agatataatt caaatacgta tataatgaaa
    18781 ctaaagataa atacggagga aaatatatga ttataaaaaa cttaggaaat gttaaatcaa
    18841 tagatataca cgttaaagat ttgctgattt ttactgggaa aaataatacg ggaaaaacat
    18901 ataccagcta tattttatat ggaattttat cagaactctt tggagcaaga tttttcaatt
    18961 atttttctca tacagaaatt gaaccacatt tacaaaatag tttaaatatt ttattagtta
    19021 gcaaagactc tataaggaaa aaatttaata atgatgcaaa aaaattttta gaagaaaatt
    19081 taaaaaaaat tgcagttcgt aactttaaag taagtgaaaa taacttcaaa aatctttctt
    19141 ttactatttc agattcagaa attagtgagc tcactggtga tatctttaat tatgagatca
    19201 aaagatacag tataagtggc attgttataa caattcaaaa tgtaggagag aaattaaaaa
    19261 ttagctttga gccaactgat tcatttcagt atcttagcaa agatattgaa attgaagata
    19321 tttataaaat tttagctcaa gagctatcta aaaatgttat tagtttgcca aaggtttttt
    19381 attttccagc cgaaagaact ggtataaatg tctttaagaa cgaactaaat gaaagtcgct
    19441 taaaaacata tgataccttg ctgaatactg tgcaatttac taatttaact aaccaaaaaa
    19501 agaaagctgc cctcaagtac gatctgttaa aaaagaatat tgagctgtta atggagacaa
    19561 cggataatag ttcttatcca aagccaatat cggattatat taattatctg aataacatga
    19621 aaaatagata tgaacagaaa aatgtcaata atatagcatc atatattaga gatgagatta
    19681 ttatgggtaa atatgaaatt gacgaaaaag ataattctgt aagttttaga caaaagtttg
    19741 gtaaaaatag atatagaaaa gaacgaattc cttttcacgt tgtgtcttct tcgattaaat
    19801 ctctatatgg attagattat tacttagaaa attcaagtaa agaaggagac tatcttatta
    19861 ttgatgagcc agaattgagt ttacatccag aaaatcaggt taagttagca aaagtaatta
    19921 cagatatagt tgagagtaaa attaagctaa ttacttctac ccatagtgat ttatttgtac
    19981 gtgagcttac aaatattgtt attgaaaata aattaaatag taagaataat aaaaaaaata
    20041 aattgtctga taaaaatata ggcatatata attttgtagg aaataatgat ataaatgaat
    20101 tagaaaaaat t
//
LOCUS       DAIGUC010000053        19186 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.053, whole genome shotgun sequence.
ACCESSION   DAIGUC010000053 DAIGUC010000000
VERSION     DAIGUC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.053"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            26..463
                     /locus_tag="NOB46_002125"
     CDS             26..463
                     /locus_tag="NOB46_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059048.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            558..1442
                     /locus_tag="NOB46_002126"
     CDS             558..1442
                     /locus_tag="NOB46_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI1059049.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            1666..4833
                     /locus_tag="NOB46_002127"
     CDS             1666..4833
                     /locus_tag="NOB46_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059050.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            4853..5398
                     /locus_tag="NOB46_002128"
     CDS             4853..5398
                     /locus_tag="NOB46_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HCI1059051.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            5426..5881
                     /locus_tag="NOB46_002129"
     CDS             5426..5881
                     /locus_tag="NOB46_002129"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HCI1059052.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            5878..6636
                     /locus_tag="NOB46_002130"
     CDS             5878..6636
                     /locus_tag="NOB46_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI1059053.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(6722..7462)
                     /locus_tag="NOB46_002131"
     CDS             complement(6722..7462)
                     /locus_tag="NOB46_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1059054.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            7523..8776
                     /locus_tag="NOB46_002132"
     CDS             7523..8776
                     /locus_tag="NOB46_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI1059055.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            9098..9325
                     /locus_tag="NOB46_002133"
     CDS             9098..9325
                     /locus_tag="NOB46_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI1059056.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            9448..9774
                     /locus_tag="NOB46_002134"
     CDS             9448..9774
                     /locus_tag="NOB46_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI1059057.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            9842..10555
                     /locus_tag="NOB46_002135"
     CDS             9842..10555
                     /locus_tag="NOB46_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI1059058.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            10865..11716
                     /locus_tag="NOB46_002136"
     CDS             10865..11716
                     /locus_tag="NOB46_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1059059.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            11837..13702
                     /locus_tag="NOB46_002137"
     CDS             11837..13702
                     /locus_tag="NOB46_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1059060.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            13750..15159
                     /locus_tag="NOB46_002138"
     CDS             13750..15159
                     /locus_tag="NOB46_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCI1059061.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            15267..15968
                     /locus_tag="NOB46_002139"
     CDS             15267..15968
                     /locus_tag="NOB46_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1059062.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            16127..16606
                     /locus_tag="NOB46_002140"
                     /pseudo
     CDS             16127..16606
                     /locus_tag="NOB46_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            17454..18029
                     /locus_tag="NOB46_002141"
     CDS             17454..18029
                     /locus_tag="NOB46_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HCI1059063.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            18029..18469
                     /locus_tag="NOB46_002142"
     CDS             18029..18469
                     /locus_tag="NOB46_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI1059064.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            18485..19186
                     /locus_tag="NOB46_002143"
     CDS             18485..19186
                     /locus_tag="NOB46_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI1059065.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         6421 a         3198 c         4123 g         5444 t
ORIGIN      
        1 aaaaaatgca cgtagaagta gataaatgga gtggttttgc aaatttcttt tatttctaga
       61 agttattcac gtatacggat ttgtttttct cacaaataaa aaggcaggaa gtacaatgga
      121 tcatttgtat ataaaatata ttcatcaatt ttccgttttg gtgttaggca cactaattat
      181 agcggggatt gtcgcattta ttattcaagg ccgtgacata ttaacagtac atcaagagtt
      241 tttcagttat gcatttggta ttcctctgat cgctataagg tctgataaca aaaagtggaa
      301 gaaacgctat tacattctct tgctattttt gtgtttttat ctgccaccta agatttttac
      361 tttattaggt atacaatgcc tatcattttc ttttatttcc tatatcattg ttttaatttt
      421 cctcagtttc atagtatgga tgttttatct tgtcaaaaaa taaatgaatg tttcatgaac
      481 agtacttcat cacagcctaa tttttttctt tatgctatcg ttatattaaa gaaatcaatc
      541 agaagggaaa gaaagtgatg aaaaaagttt tattagtggt aaaccccagt tcaggcggtg
      601 aacaagcaaa ggaatttgag caattagcga tagcaaaatt ggaatcggtg tttgatgaag
      661 tggtcgtctt gcatacaaaa aaagcagggg atgcaaaaaa ctttactcgc gaagcggcta
      721 cggaagggta tcatagtgtg tttgtcatgg gcggagatgg aacagtcaac gaaggaatca
      781 gtggaatcgc tgaacaagaa catcggccaa atttcggatt tttcccattg ggtacggtga
      841 atgacttggc tcgagcatta gggataccgc tagaacctga ggaagcgatc aatcattttt
      901 cgattgaatc agtcaagcca ttggatattg gaaaaataaa tgacgactat tttatgaatg
      961 tcgtcgcaat tggctctatc cctgaatcaa tcaatgatgt agatgcggag aagaagacga
     1021 aatttggaaa actagcttat ttcatgtcag gaatcaaaca gttagcttcc acacaatcct
     1081 actcgtttca cgtagaagtt gatggaaaga aggaagaaat tgagagcagt accttgctga
     1141 taggactaac taactcagtc ggcggttttg aaacattact tccaaatgca aaagtggatg
     1201 atggtaagct ccatttggtt tatttaaaag attcttcttt gatcgatacg cttaaaacat
     1261 tgccagacct attaaaagga gtagatgaat ctacgaaaaa tctagcctac cttacttgtg
     1321 agcaattagt tgtgtcatta gctgatgagg aagaattgac gacgaatgtt gatggagatg
     1381 aaggggataa attacctgtg acaatcaaag tattgccctc acatttacag gtttattgtt
     1441 aaaatggagg ttgtgaccga ggagttggcg ggagaacacc gcttgttcgg gataagggac
     1501 tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa aagaaattta cacctaatag
     1561 aaaaattttt ccataaaaat acatatttta aatatgaaag tacaattgga aatagattaa
     1621 aacgataaaa taaaattgtc aaaacgtcag agaggatggt ggagaatgaa tcaatgtgta
     1681 aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct tgatggtgac atccgttttt
     1741 gccgatgtag agaaaacaaa cgaatcaacg caatcagaga atcaaagttt tgacaagact
     1801 actttttcag aagaatcgat tacttctgaa actacagaat ctcaaagtga ggcttctact
     1861 aataaaaggc aagaagaaaa taagacaagt gagacctcag aagtagctga acaaacgtct
     1921 gatagcagtg aagcggcact ggcaagagct gtttcagcgg atgggtacag cgaagctgcc
     1981 acaacagaag aactggcgca gcttctcgca gacgaatcag taactaagat ccgactgatt
     2041 cagcctttga ctttagacag ggaattagag atcaaacgag atatcgttat tgattttggt
     2101 ggattcgctc acaatttcgg cacacaccat atttatatca atgagatacc tcagtcgatc
     2161 gagttccaga attttaaagg aacagctgca catccaggtg gattgacacc aaatatcgat
     2221 ggaaatgcca ttatcattgc ttatatgacc gatttttggg gaagcagata tcattttacg
     2281 ggagaaataa aatttaccgg gacacttgat ttgtatgatg ggtccaaatt aggactgatt
     2341 tacgctcctc gtgcaactgt cacattagat ggtgtttccg gtgtgttgga tgtccaacca
     2401 gtgaaggaag gactgaatgc cgctccgggt aaagcctatt tttgtagaag ctatcaattg
     2461 aatgtgatca atggtagtca actttatgga ccgtatctag ggaaattcta cggttttcta
     2521 gattcaggag atgagactgg tagtggaaaa acagcgccag gaatccatat cttaagcggt
     2581 tcaaaggtct ctcttgatta tgatcgggca gatggcgtta gcgatgaagg agaggcagtc
     2641 gatacgctac ctggtaatgt catgtttgaa gtcagtggtt cgggaagcga attttcggta
     2701 aatacaaaga tcaatattac caatgacaac aatcgcggaa tcatccaaat gagaggttca
     2761 ggatcgaaag tcactgtatc gaatggtggg aaaatcacca tcaatacagc aactacgggc
     2821 ggatttcgct tgcaaggaga ttctagtcaa atccatgtat caagtggtgg acaaatctcg
     2881 gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg ggatgcgttt tgtaggaaaa
     2941 ggcctttctt tgatcgtaga aggagccgga tcagttatcg acatcgataa gcagagtggg
     3001 cgttccagcg cagttcgttt tgagaatggt acgcaaaagc tgacagtaac caatggaggc
     3061 tcattgaggg taagaaatac aggtgatggc aaatcttacg tgaacagact caatcaagga
     3121 aatcaagcga tccaatttta tgacgcttct ggttttctag aaagtccagg ttcagctgat
     3181 tttacagtca ctggagaaaa atcaaatatc gatatacgcg cagattccgg agcaactgta
     3241 gatacaactg gagatattga tttaaatttt acggcaggtg aaaaaactta tttagtcatg
     3301 gtcgggaaaa caggggaaga taagaccggc atcatcagtg gggatgtgtt gaatgtggac
     3361 ttagaatctc ctacctattt tgatttccaa aacaaacgga ttggaagcga gaccaatggc
     3421 ataggcggct gggtattcca aggaaatgga gattcttctt taaagatcgc ccattcagaa
     3481 atcgctttat ggcgaaaaac aggcgcaaca ttcgataact ttgaaaaaga cccggattat
     3541 ttttctgata tgacagactt atcgatcaat gggaccgact taggcaattt cgtatcaagc
     3601 cctagtgcag gtttaacaaa tgaatttgct cagacaggtg ccggaatgaa aaattataat
     3661 cgaatcagtg ccaataatca gctcccgatg attgaatcct taagagtgcc aacgaatgca
     3721 gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg tcgaggcaaa gccaagagat
     3781 gcttggacag gcgaagtaga agtgacttta cgtattactt acgcagatac gacgaaatca
     3841 tctgtagaaa ttactgctct cacgcaagga caaacagatg aaaatgaagg ggcaggatat
     3901 aacccatggg gagaaggcga acaaggcggc ttgttcgaag ttcaagtacc caatgatgag
     3961 agattaaaaa cggaggatca agtgcaagtt gttgctgcta aaaaagtaag aggtggccaa
     4021 gaagtgacag aactggactc tgccaaaacg acagtcgatg tgattcctcc tgaacctgct
     4081 aatttaagta ccacattgat caatgcagct tctcgcacga tcacaggtac aggtgaagca
     4141 ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt cagaaacaac tattgatgat
     4201 acaggggaat ttgttctttc tatcccagaa aatcaacttt ttgcaggaga tgtattagaa
     4261 attgtattaa acgaccaagc aggagaagct actgctaagg gtgtgcagaa caagccaagt
     4321 accaacgatg aaattgggaa tcacaatcca agtgatacgc cagttgttta tcatgatgcc
     4381 ccgccttttg cacctgctac gaagatcgta gtagaaggtg gtctctcatt tcttgcccct
     4441 tccaaactcg attttggtca gatcaaagca actggtttga cacaagaagc atttggccaa
     4501 atggatatac aggaaaaatt atggatttat gatcagcgag aaacgaaaaa tccgtggatc
     4561 ttaacgataa aattatctca gcctttcaca aatgatgcag gattttctat gcaggatgtc
     4621 ctatatttca agaaaggaga ggagtatcaa ttagtgaatg aagaagaact ggaaattgtc
     4681 agaggacaaa attcaacgaa tgtgcaagca gattattcag aatatttaaa taacggtcgg
     4741 gcgtttaaac ttgtcttaac caaagaaaat cagatagctg gtaattactc agcagagata
     4801 acatggacat tagcagatgc gccgacagaa taaagatcaa ggaggatgat tgatgaatcg
     4861 aatatggaat aaaagtcatc gaaacaactg ctctttactt atgatccttc tccttggatt
     4921 catcctttgg cagacacctg tccatgcctc cgaattcaat tttgcggtag attttgaatt
     4981 accggctaat cagattgata agaacaaaac atatataaat gtaaggatgg agcctgggaa
     5041 aacacaggaa atcccctaca cggtctttaa ccgaacagat aaatcagtaa cagttgagac
     5101 attgatccac tccgctacga cgaattcaaa cggtgtgatc gaatatggag aatcaaaaag
     5161 taaatttgat gaaacattaa gttatgatat gaaaaactta gcaaaaacag tgggagaaat
     5221 aactgttcct cctcaaagtg cggtcactga gacactttca ctgaaagcgc cagaaaaaga
     5281 gctggctggt gtggtcgcag gagggatcac gtttcaagaa aaaaaagaga acgtttctaa
     5341 caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg aaagcaatct tgatttgaaa
     5401 tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa gcttatgcgg atcaaagcga
     5461 tggaagaaat gtgattaagg cgaatcttca aaatccaaat gcttcttata tgttcggctt
     5521 gactacatcg gttgaaatct acaaaaaaga aacaaaagag ccttaccttt caataaaaaa
     5581 agaaaaaata gatgtagcac ccaatacaaa ttttgattta cttgtcccat tagaaggaaa
     5641 aaaattagct ccgggacatt atcaagcggt tgtgaagggt gcttggaaag aaaaacgctg
     5701 gaatctccat accgattttg aaataactga tgatgcagcg gaccaattga atgaaaagga
     5761 tattgattta aaaaatcagc cagaaacatt tgactggcga tggctgatac ttgttggagt
     5821 cattcttatt ggcttatttg ctggattatt tattttaaaa gaaagaagga aaaagaaatg
     5881 aaaaaaacaa ttgcattaag taccgttcta gctggaagtc tattattatg tacacaaagt
     5941 gtttttgctg agaataagag ctcagccact acagaaggaa cgatttctgt gaccaaacca
     6001 gatgctgcaa atcctgaaga cgttgttcca gttcctcctg ttgatccaaa tgatcctgat
     6061 actcctttta cacctgacga accaaatcag ggaacatccg gattactgac gattgaccaa
     6121 gctccagatc ttgattttgg aacaatcaag ttaggtacag caaaaacagt atatgctgca
     6181 ttacaaagcg gaacggacag tactggagca caaacacaag tacagaattt cgtacaagta
     6241 acggataaaa gcggaaatta tgccggttgg aaattatcag tcaaacgaac agaatttatt
     6301 ggtacaacat ctgatacgaa taaactaact ggttcaaagg tgaaattcaa aaacgccgtg
     6361 attcgaaata gcgcaactaa tagcagtgga atgccatcta ccgtttctgg aactggcgct
     6421 gaaggaatcg aaatcccagc agatcaggca gtagatctag taactgcagg agcaaatgaa
     6481 gggattggca catggattta ttcattagga gagaatgtgg aacaagggag acaatcagtg
     6541 gaattatttg ttcctgtatc caattatgct gtagacaact acgtttcaac attcacatgg
     6601 tcgttaacag atgctcctac agaagaggaa gcgtaaaatc atatcaacga tttcagggag
     6661 tggagccgat tcaaggccca ctccctgaaa tctgctatgc ttacgtctca gctcttattc
     6721 atcaactcga agcagttttt tggaagtcat ggaaacgttc ctttgtcttt tcaaagatct
     6781 ttcgaccaac gagtaaggag tcaccgttga aaaattctaa cacataatga gcagaatcaa
     6841 ttttctgcaa ttgcgataag ttgatacagt aagattttaa aagtaaaaag taagcatact
     6901 tttctaactc tgtcttcaat tgttttaaag aagtattcac taatttatct tctgtagttg
     6961 ttttgaccat aacttggttt ttcaaacctt tgatactttc aatatataaa atttcccgag
     7021 gatacaggac gagacttcca cctttttgat caataaagat tttatcgaca tttacgatct
     7081 gctgttcttt ccaattgatc tgttctagca cttgacgaat ttgttcagat aaattcctgt
     7141 cttttctgat atatccaatc ggaaggattt tccgattgat gatctctact gcaaaattcg
     7201 tataagcggt gaaaaaaaca atattactat gtgcattttt tttacgtatt tgttcggcga
     7261 catcaatacc tgtgagtgat tgcttcaagt cgatatcgat aaagaaaaca tcgtgattat
     7321 caatagtgcc caactggatc aactgattga tttgagagat agaagtgagc tgcacgatat
     7381 tctcgatatg atgattgacc aattctctga tgatccattc gctgtgaaac tggttatctt
     7441 ctatgataaa atactttttc atatgcaggc tcctattaaa aaaatatgtg tacattttga
     7501 aacaaaacaa tggaggaata agatggtcgc aacagtgaca ctttatttga cctttacttt
     7561 gattttagat ttaggtatct atttattctt ttcgaaacaa ctgctagtaa aaaacagctt
     7621 tggttgtata gctttgatgg tggtgacact tttacttcct atccctaaag tgagctttcc
     7681 ttacctagtt ggcttattat tgatgtttct tttttatttt actacgaaaa acctgtttat
     7741 cagctgtttg atcagtaatc ttttttttgc tatcactgga ctcagctttt ttctggtttt
     7801 tgatctgatg gattatttag gaaagagaca tcttggaaca gcaagttttt ttgcactact
     7861 tatcgcattt attttctatc tattagtaaa aagtatagac aaacagacga gatttctcaa
     7921 cttgcttttt acttatccaa ctgaacacta ttttggaggt atttgtattt tattaagctg
     7981 gggcgtgatt tacttggtat tgggaagtgt tcacttccgc tcatctaatt atctgcttct
     8041 atctcttttg tcgatagtca tcagtttttt ttctttgttt ttttccatta tgttgatcag
     8101 tttccaagta aaagaaagac aacatcagga atcgcttcaa ctgtatcaaa taaatgaaga
     8161 atattaccat catctagagg aattcaaaca tgattataaa agtctactgt tttcattaaa
     8221 aattactctt caggaaaata aaaaagaaac gttggaattt ttagaaatat tagaagatca
     8281 ttctgcagct atttttgaaa aaccgcaaat acaacagcta acaaatattg tatccccagc
     8341 tgtcaggggt gtctttttaa aatttctaga aaaagcagaa tcggagaaaa tcccgatcca
     8401 agtagttatt cctgtcgaag tgaaaacaat cccgattgat ctggttgttt ttattcgctg
     8461 tttatctatt tttatttcta acgcattcga tcatcgtgta gccgatcaga gtccgattac
     8521 gatcaatctg ctggaagaaa aagagggatc acgttttagt atagcgaaca aggcaaatcc
     8581 aacgaatttg acgctatcgg agatggtcaa aagaggaaaa acctctaaaa aaaatggcgg
     8641 gttaggtcta tacagtgcga aaaaaatgtt ggatgtttac gaaaatgcag aactaaaaat
     8701 cgaattttca aaacagaatc actatttttt tgtagaaatg tatctggcat ctagaaagag
     8761 caaatcagcc tactgactta ctgtcaaagg ataagtttga ggaaagtcta cacggagata
     8821 gagacaacaa cacagcatat tcaaaagaaa cagaagcgtg atgaccgttg tcacccttct
     8881 gtttcttttg ctatgtagtt aaacaaagta gttgacactt ccgctactta gtattagtac
     8941 gaaagtatac ttcatgatac taagtagata agaagtgaaa agcggaaccc acgatcgtca
     9001 aaatgctaac tgctttgctt acaccagata aagggaagag caatatcgct tattttaggc
     9061 gtggagaagc aagcaaatcc ctacgatcac aaaaaaaatg ctgacccagc agttaagaga
     9121 gttagaacaa gatgaaagta tccatcgaaa agcctataac caagtcccgc ctaaagtaga
     9181 gtactcgctc accgaagaag gaaaatcatt aagagagatt ctagtagcgt tgtctgtttg
     9241 ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa gaagacacgc tactgcatac
     9301 acatggtggc tacctaaatt attgattttc tatgacattt attttaaata aaagaaaaca
     9361 ggagtttttt taaaagcatc atctattttt tatgtaaaaa aatggtatga ttaatcaagt
     9421 aagaagtgat tggaagaagg caagcaaatg aatagtatgg aaaaagtcaa ccagtttaga
     9481 gatgaacgta attggcgaca atttcataac gaaaaagatt tggctatctc tatttctttg
     9541 gaagcatctg aattgttaga actttttcaa tggaaaacgc cggaagaagt aaaagaaaca
     9601 caattagaac gaatcaaaga agaactggca gatgtattga tctattcata catgatggca
     9661 gacaaccttc acctggatct agatgagatc attgaagaaa aattgatcaa aaataatttg
     9721 aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat acacagagtt gtagaaatgt
     9781 gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa atgagtctgg agggagagaa
     9841 aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat atcctcttgt tcctcttgtt
     9901 attagtagga ctagctttga ttttcaatga acagatcaag gattattttg tcagagagac
     9961 aggagataaa tatgctatag cgaatgtaac aaaagaagat ctgaaaaaga ataacgataa
    10021 agatgtcagt tttgactttg atgcggtaga accaatgacg acagaagggg tcatgaggtc
    10081 gcaaatgaga ggaacagatc taccagtgat tgctagtatc gcagtccctt cagtttcaat
    10141 caatttaccg gttttcaaag gcttggataa tacgtcacta ctttacggag caggaacatt
    10201 atctccagat caagaaatgg gaaaaggaaa ttatgcctta gcaagccatc gtgcaacgaa
    10261 ccctgaattg ctgtttacac cgctagaaaa tttagagatg ggtgccaaga tctatttgac
    10321 agatttagaa aatgtgtata catacaaaac attttttaaa gaaaaagttg ctcctacaga
    10381 tacccaatta ctgaatgaag tcgagggaaa agaaattgtc acactaatta cttgtggcga
    10441 catggacgcc gtcacgcgac tagttgtaca aggagaactg gaaagtgtta catcgataaa
    10501 agatgcgaca gatgatatga gatctgcttt caatctagag acaaaaacat tttaggatac
    10561 tgggacataa gtcgttacag attaaaaaca gccaaaggat atgaatcgat aaggaaaaac
    10621 caatttgctg aaaaaaagag aaacgcaaag aggtgcatct ctgatttggt tgttttctag
    10681 atagacttgt gttccagttt ttttattttt tatatgaaaa ggcttgcata aataaaaatt
    10741 cgatggtatg atgattttga ataagaaatg gattgttact gtacggcagg caaaaccaga
    10801 attcagctaa gaaacagtag gcgaattcta ggttttttta tttttcttga gagggcgaag
    10861 caaaatgaaa attgataaaa ttttgaataa caatgtcgtc atttcgaaaa atggattcgg
    10921 ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa aaaaagattg gggacgagat
    10981 ttcgccagaa gcggtccaaa aagaatttgt tttaagagat tcttttgcta aaaaccaatt
    11041 ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac aagtagtcga
    11101 actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga cattgaccga
    11161 tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta atccattatt
    11221 atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg ctcttttgtt
    11281 cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta ttgcctttca
    11341 ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg ctaccacaat
    11401 ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg atgaagaatc
    11461 tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt atctcaaagg
    11521 ggaaggatct gacgaacaag atgaatttct ctacgcatta gttcaaggaa agtatccaaa
    11581 agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa aacaggaaat
    11641 ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa gtgagaaaaa
    11701 aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt gaaaaaatag
    11761 gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta aataaaaaag
    11821 aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg aagcggtagg
    11881 aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat tcagattaaa
    11941 agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga tccaagtcgt
    12001 acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg tttatcaatc
    12061 gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt ccaaaaatat
    12121 tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag gggcgatggc
    12181 agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct ggctgacagc
    12241 tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta ccttcttacc
    12301 tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt tagcagtagc
    12361 aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg gagaagctat
    12421 cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt ctgtcatacc
    12481 aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa aagtgattcc
    12541 gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg ttccattaac
    12601 atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg gtctcttcaa
    12661 ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt tatggcaagt
    12721 attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga atatcgaaca
    12781 atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac aaggtggggc
    12841 tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag ggatttcttc
    12901 tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga cattaccttt
    12961 gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta ttatcggatt
    13021 ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc cgactttcat
    13081 taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta caggaattgc
    13141 ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa cacaagacaa
    13201 tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac ggcatacctt
    13261 aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc aagttttttc
    13321 ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac tagttgcacc
    13381 tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga tcacaacgac
    13441 tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa atgggaatgg
    13501 ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat tgattcgttt
    13561 tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg tcattacgaa
    13621 tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg caaacgaaga
    13681 tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt tcagaaaaat
    13741 ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga tcgagacgga
    13801 aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc gattatcggc
    13861 agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa tcatcgagga
    13921 atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat gggattcaaa
    13981 tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga aggtactcct
    14041 aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa atatgatatt
    14101 gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa agaatacggt
    14161 ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac agtattagag
    14221 agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc ggcctttcac
    14281 tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta ccaaaatatt
    14341 ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat cggccacgaa
    14401 ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta cagcatcgat
    14461 gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa ttttttctgc
    14521 acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca taaaaaatat
    14581 ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct aaaagaatat
    14641 ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga gactgatcca
    14701 caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt tcttgaggca
    14761 agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa tgaattatac
    14821 aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat tgatcatatg
    14881 gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg tcatatcgaa
    14941 gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc ttggggatgt
    15001 atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt tatctatgtg
    15061 gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc ttttgattgg
    15121 tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct gaatgaaaaa
    15181 gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc tattctttta
    15241 gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac ttggaagtcg
    15301 cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg atgttgccga
    15361 cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga aaggcaatcg
    15421 aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg acggttctaa
    15481 gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc ttggagaact
    15541 cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata aagaaggaag
    15601 atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta tattatttga
    15661 acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg caattcagca
    15721 gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga tatactattg
    15781 actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa ggaattctga
    15841 aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa attggggaaa
    15901 tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat attgattatg
    15961 aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    16021 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc agatacacgg
    16081 ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt cagaaggaat
    16141 ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg gcttgacgat
    16201 cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag aaatcgatac
    16261 attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt tccctatcgt
    16321 attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag taggtggcgg
    16381 attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt ttgcagtcgc
    16441 tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt ttgtcacagg
    16501 aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca tccaagaaga
    16561 aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga ggcagaatgg
    16621 attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga aagaatcaga
    16681 gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg tccagagcat
    16741 cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg tcgaaagggt
    16801 ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact attccaaaaa
    16861 ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga gatcagtaca
    16921 cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg gttatcactg
    16981 aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct atttatcgtt
    17041 aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg atcgtttagt
    17101 tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca cgagaacaaa
    17161 atgatttttt cgttaataac agaaacaagt atttgttgtt taaaataata cacgttattg
    17221 gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc gatgaaaaca
    17281 cgttatttat ttttgtttta tctataaaat ggctgaaaaa tgattttttt ctaaatacta
    17341 tatatagtgg cgtctatcct atataccact aaaaaactac aaaatctagt cttttatttt
    17401 aaaaaaacac gtgtagaatg aagatagact tttgagttag ggagtgtttt tttatgaaac
    17461 ttactgtttt ttgcggttcc cgttttggta ataaagaaag ttacaaattt attgcgcaaa
    17521 cgttaggaaa atacatggca caagaagaaa tcgaactggt ttacggtggt tcatactccg
    17581 ggattatggg agtgattagt aaaacagtac tggaaaataa cggaaaagtc acaggtatct
    17641 atccgaatgg gctttttgaa actgaattgc ctggaaaaga tgttactaca tttattccta
    17701 cagaaacgat cgatgaaaga aaggtattat tatttgaaaa gggagatgct gtcctcgttt
    17761 tccctggagg tctaggtaca ttggaggaat tctcacaact tctttcttgg atagcaatcg
    17821 gtctgacgcc cgacaagcca atcggaatat tgaatattgg cggttattac agcggcttgc
    17881 aacaattatt agaaactttt gcaaaagagg attttatgga taaaaaatgg ttggatcaag
    17941 taatcttttc caacaatcca ttggaactgg tcaatgaatt acgagcagta tctattaaaa
    18001 atcagttatt attgaaggag gcaaaataat gagtcaaata tatttagcag gaccattttt
    18061 ttcagaggag caaatcgatc gagtaagtcg tatcgaaaaa gcgttggagg aaaacaaaac
    18121 agtcacaagt ttctactctc cacgtcatca ccaagaaagc aattatgaac tattcagcgc
    18181 tggatgggcg caggaagtat acgaaaaaga tatggaagaa ctgacaaatg cagaatttgt
    18241 tgttgctatc cttgactttg agcatcaaac aatcgatcca ggaacggctt acgaattagg
    18301 tgtggcaact atgttgaaaa aaccgatgat cattgtacaa gaagagacgg tacctacgaa
    18361 cttgatgatt acacaaagtc tccatacgta tttaaaatca gaccaagctg tacgtgaata
    18421 tgattttgaa acattgcctg ttgaaactta cgtaggcgag tacttataga agaggaaggg
    18481 ttgtatgtca gtgattttga tttcaggaac gattggtgca ggtaagagca gtttgacgga
    18541 tatgcttgca aaagagattg attctaaacc attttatgaa aatgtcgaag ataacgaagt
    18601 attgccgctc ttttattcaa atcctgagca gtacgctttt ttattgcaaa tcttcttttt
    18661 gaacaagcga tttttagcaa tgaaaaatgc tttagtgaac gatgacaatg tgctagaccg
    18721 atccatctat gaagatagcc tgttgttcca tctaaacgct gatttaggtc gggtaacgga
    18781 tatcgaagta cagcagtacg atagcttatt agatacgatg ctaaacgagt tagatgatgt
    18841 tgctccaaaa aaacggcctg atttgatggt ccatatcaaa gtttctttgg acacgatgct
    18901 agaacgtatc aaaaaacgtg ggcgtgacta tgaacagcta gaaagcgatg agacgttata
    18961 tacctattat gaaacgttga acacccgcta taatcaatgg tatgaagatt ttgatgtatg
    19021 tcctaaaata caagtggatg gggataaatt cgattttgta gaaaatccag aagatgcaaa
    19081 aaaggtgatc cgtcagatcc aagaaaaatt agctgaattg gaaggaaagc ctgctggaaa
    19141 atattttacg gataaccagc atgcaaaagg tcaagaatta ggctaa
//
LOCUS       DAIGUC010000054        19140 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.054, whole genome shotgun sequence.
ACCESSION   DAIGUC010000054 DAIGUC010000000
VERSION     DAIGUC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.054"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            105..1148
                     /locus_tag="NOB46_002144"
     CDS             105..1148
                     /locus_tag="NOB46_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCI1059066.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            1321..1545
                     /locus_tag="NOB46_002145"
     CDS             1321..1545
                     /locus_tag="NOB46_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059067.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            1548..1805
                     /locus_tag="NOB46_002146"
     CDS             1548..1805
                     /locus_tag="NOB46_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059068.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            2022..2897
                     /locus_tag="NOB46_002147"
     CDS             2022..2897
                     /locus_tag="NOB46_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059069.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            2907..3701
                     /locus_tag="NOB46_002148"
     CDS             2907..3701
                     /locus_tag="NOB46_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059070.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            3730..4848
                     /locus_tag="NOB46_002149"
     CDS             3730..4848
                     /locus_tag="NOB46_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059071.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFAKSKDEVKGVVIDDDFEFDFD"
     gene            4881..5201
                     /locus_tag="NOB46_002150"
     CDS             4881..5201
                     /locus_tag="NOB46_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059072.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            5458..6147
                     /locus_tag="NOB46_002151"
                     /pseudo
     CDS             5458..6147
                     /locus_tag="NOB46_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
     gene            6148..6351
                     /locus_tag="NOB46_002152"
     CDS             6148..6351
                     /locus_tag="NOB46_002152"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059073.1"
                     /translation="MSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNA
                     YIARLKRFIDKYKENSDKFSKDK"
     gene            6371..7999
                     /locus_tag="NOB46_002153"
     CDS             6371..7999
                     /locus_tag="NOB46_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059074.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            8050..8418
                     /locus_tag="NOB46_002154"
                     /pseudo
     CDS             8050..8418
                     /locus_tag="NOB46_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8518..8718
                     /locus_tag="NOB46_002155"
     CDS             8518..8718
                     /locus_tag="NOB46_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059075.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            8852..10078
                     /locus_tag="NOB46_002156"
     CDS             8852..10078
                     /locus_tag="NOB46_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059076.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            10928..12253
                     /locus_tag="NOB46_002157"
     CDS             10928..12253
                     /locus_tag="NOB46_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI1059077.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            12246..12593
                     /locus_tag="NOB46_002158"
     CDS             12246..12593
                     /locus_tag="NOB46_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059078.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            12908..13765
                     /locus_tag="NOB46_002159"
     CDS             12908..13765
                     /locus_tag="NOB46_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HCI1059079.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            13785..14345
                     /locus_tag="NOB46_002160"
     CDS             13785..14345
                     /locus_tag="NOB46_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HCI1059080.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            15311..16078
                     /locus_tag="NOB46_002161"
     CDS             15311..16078
                     /locus_tag="NOB46_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HCI1059081.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            16104..16649
                     /locus_tag="NOB46_002162"
     CDS             16104..16649
                     /locus_tag="NOB46_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059082.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFDGQQIGLKKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            16650..17216
                     /locus_tag="NOB46_002163"
     CDS             16650..17216
                     /locus_tag="NOB46_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059083.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            17231..17479
                     /locus_tag="NOB46_002164"
     CDS             17231..17479
                     /locus_tag="NOB46_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059084.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            17499..17738
                     /locus_tag="NOB46_002165"
     CDS             17499..17738
                     /locus_tag="NOB46_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059085.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEQLLRKAQQKGYPDKMLKQIGYYT
                     PEERIEKESCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            17755..18339
                     /locus_tag="NOB46_002166"
     CDS             17755..18339
                     /locus_tag="NOB46_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059086.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEQELILERQSILCSEQDSKRLYGLYDLQLNGLKAQYV
                     ADSFDDMVGQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSIVES"
     gene            18446..18727
                     /locus_tag="NOB46_002167"
     CDS             18446..18727
                     /locus_tag="NOB46_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCI1059087.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFNEA"
     gene            18717..19058
                     /locus_tag="NOB46_002168"
     CDS             18717..19058
                     /locus_tag="NOB46_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI1059088.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWVDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIERLQRKV"
BASE COUNT         7336 a         2414 c         3847 g         5543 t
ORIGIN      
        1 acaacaacga ttatgatctt aaaacaatcg tttatgtaat tggcaatctt acgaataatt
       61 ttcatgcaat aatgacaata aaaaatgaaa aggggtaaaa tcaaatgaaa aaatttttag
      121 taggaattct attcacaatg gggctagtat tattatcacc ttcagtttca gcagaaagct
      181 ctatttccat gtatcgtatg tataatccca atagcggaga gcatctatac actagaagcg
      241 ttggagaaag agacaatctg aaacgttatg gatggcatta cgaaggtgtc gcatggcaag
      301 ctccaacaag tggtactcct gtttatcgtt tgtataatcg gtataacggt gaacattttt
      361 acacagttga tgccggagaa agagataaga tttcacacac aggatggacg tacgaaggtg
      421 ttgcgttcta ttcctacaac ggagcaaata gagttcctgt aacacgttta tataacaaat
      481 acgtgaattg gcatcactac acgttagatc aaaatgaaaa gaacgtaatt agtaaacaag
      541 gttggaagat tgaaggtaca ggctggtatg caatgccaaa cagcgtacca aatcctacac
      601 ctgctccaag cactgaaaaa gtgttgaacg ttcctgttgt atggcaagga aatacaatgt
      661 tatgcgaagg agcttcttta ttagaaggtt tacactacaa aggtgtagcc acaaatcaaa
      721 gcttaaccag ttttgtaaac tatatgccaa aagctaatga caataatcct tatcatggtt
      781 actcaggaga gtggcgtcat aacgttaatg gaacgtatca aggcatgatg gctgacccag
      841 tagttaaatg ggcaaaaaac gttggcggta atgccgtcaa tatcactggt tcaggaacga
      901 atggaatcaa gaatgaaatt cgcaatggta atccggttgt aacttggatt acttataact
      961 atgctacgcc agagttcaaa caaatgcctt ggggtcgtgc agtatggaat ggacatgtag
     1021 ttctcgtgga tggcttcaga aatggtgcat accatgttgt tgaccctgta tttggcgcaa
     1081 aatggatcaa tgcaagcacg tatgagagag catttaatgt gactggaatg gcggttgctg
     1141 tacgttaatt gatagaatta tcaactaaat gaaataagag cttaattact gaaatggtaa
     1201 ataggctctt atttttttag aggaaatttt tgtaatacga atctataaca aaaaatattg
     1261 aatgtagtac acaaaagtgg tatattaaaa tcgtagagat tatgcgaaga ggtgattttg
     1321 atgaaccaaa gaagaagaaa aaggttagaa gaaataagcg agcgactttc cgagctaaag
     1381 gatgagttag aagtaattca agaagaagag tacaaagaaa atatacctaa aaatctacag
     1441 ggatcagaaa gatatgaaaa agcagaagaa tccgttgatc aacttgaaga agctgttgat
     1501 ggtttatccg acatattaga attgattgaa gatatagcta gctagagatg attaatgaag
     1561 atttcaggag tgagaataaa atgattgata tttcactgat agagaagcta cttttttcaa
     1621 ataagtacac agccaaagag ttggctacaa gatggcaaat atccgaatca gctattaaag
     1681 cctatcgtca aaataaggga agcgtaggat ggcgtgattg gaaaggaatc agcattggaa
     1741 aagcagaaga cataatgaaa cgtgaaggat ttcaagctga caatgattct aaaaaagttg
     1801 aatagtttaa tagtcgccaa gaaaagtacc aggacgaggg gaaaggtaga ttacaaagga
     1861 aaacactttt aaataaactt cgcaaaagca tcaggttatg agtggctagg gctatacgaa
     1921 tgtgatgaaa acaaagggct ttaatgtcaa agaaaacgca ataggggggg aacaaaattt
     1981 ttaaaaaaga tatttatgtt tggtttaatg gaaaaaaata tatgactact aacaaaaggt
     2041 ggtcagagct agtacaaaat acagttaaaa aagtcatgcc agatggatat catttcaact
     2101 atatacaatg ctcacaaaca actgaaagta tttatttttc aatattaaat gagaatagac
     2161 tctattattt cagggtaagt tcacaccata ggaaaaagag agaagataat gttacgacat
     2221 ttttatcggg aaaatacaat ggcttcaaag agttaagtga agccattggt gagtatctaa
     2281 aaagtaatag atttgtcaga atttctgaca aacatatatt gatcttgtta ctttatttga
     2341 ataatagctt caaattgttt tggagagacg acactttcta ctatattgag aacggcatgg
     2401 atatttattc tggtatcaac ggcatattaa aacattatat taaggcgtta cttcgatatg
     2461 gggttcttta tcaagaagat ttaagtaacc aaattaagat tagtaattct ggaaagtcat
     2521 tactggcaaa atataaaaaa ttgctttctc ctatctacaa aggaatagat atggaagctg
     2581 taaattctga aactttattt aatttagttg ttgatgaaaa gtttgcgaat gaatttttta
     2641 aaagtaaaaa aattgaaaga ctaaataacc tgtttcctga aaatgcaata aaagcttatg
     2701 tagataataa taaatcacga ttatacaact ggtttattcc caaacggttg cgaggaaaaa
     2761 tcaaaattgg cgatcaagtg aaagtaatta atctaaatca tactaagatc gttaccgtaa
     2821 cggagttgta tatagctgaa aaagaagata ttacaaaaat gaaaccagtt attaaaatac
     2881 tagataacaa agagtgagtg gaatatatgg tagcaaaaaa gaatactcta aaagaagctt
     2941 ctgaaaaata tcaagatatg aaaagacgag gattaatacc aaaggacaaa aaaggtatat
     3001 ggagagaatt tgttaaggaa gtcagtagtg atcgaagtgg cggtgacttt gttggacgat
     3061 atacagcaaa aggttatagc aggcgcttaa ggatcactgt tgaatatgga acgaatgaat
     3121 cagctacaga gctgaagcaa aggtacttag atacacgaag agaagcttca aaaaaatatg
     3181 atgatttcaa gagcagaggt ctaattccta agaagaaaaa ggggatttgg cgtgagtttt
     3241 tcaaagaaga agatagcaat cggaataagg gagacttcat tggacgatac acagcaaaag
     3301 gctacactaa gaatttaggg atcaaggttg aatacggaac tggtgaaagt tcatgggaat
     3361 tgagaaatcg ctatttaaat acattgttag agaaatataa agcagaatta ttggagttgt
     3421 tcgatgttaa tgattttatc gagatggctg aaaagtatgg tcatgaagaa ggttttatga
     3481 tcaatgacat tatggttatt gataatttta cggatttatt agcacttgcg aaaaaagcaa
     3541 gggatttaag agaaacgcag atgtatctat tcagaaataa aaacggaaga aaccggagaa
     3601 ctgaatcgag tgagattgaa gattactatg atgcctttac acacgatctg ggagcctttg
     3661 tagacgagat aagtggtgta atgaacaaat atagggtcta gaataaaaaa gccggagatg
     3721 agcagataaa tgggaaacaa tagcatatac acacctgaaa tgcagaataa aattaaaaga
     3781 cttgtcggat tagggtggat gacaagagga aaattagatt cttttagtac gatcaaatat
     3841 cttttgatgg acatttaccg tcagaacaag caaacaggaa tacatttttt gggctatgat
     3901 aagccggaag atgcaccttt ctttgttcca agttcagcct atagagccag tacctccggt
     3961 agcatgtata acttggattt gtttgaggaa ggagcaaaga tgatcgaata tgatttcaac
     4021 gaagcctatt cgaggatcat gagaaattat cctttgccgt caaacactta tttgaaagca
     4081 aaatataata cagatcaagc tattttgaga gcgataaata gaccaaaagt aagaccgtat
     4141 gaaaatttaa aaacgtatat gttctttttg gttaattttg aaggaacagc caaagaagga
     4201 acatatgcta atccaaaatc acagtcgatg tttgcggatt atggcgaaaa tcccaaaaca
     4261 gctaatgagc ctatttggtt atcggagatt gagctaacac ttatccttga ttattatgat
     4321 attaaagaga tggaagtcct agatagccac acatttttga cgaaaaaagg attactcaaa
     4381 gaatattttg aaagaatcga gccattaaaa actgatcctg atacgttgaa gctttataaa
     4441 aatcttagaa cgaaagtatt tggtgctatc ggacaaaaat cattaagaga aggagaaaca
     4501 agcaccttcg ataaatacag tatgtataat cgagcgtatt cctccatggt agcaggcgta
     4561 tttagagatc gtatggttag atatgaacag aaatacgttc atagcgctta tgggctatta
     4621 aaaattcgta ctgatggatt gtatttcaga tccgaagtac cagagtttga agagctgtat
     4681 aaacttggag tagttaagaa aaaagttcat acaatatcca aagaagaagt cgaaaaagct
     4741 ttagaattta aaaataaagg atttgaaaat aagggctcct ttgcgaaatc taaagatgaa
     4801 gttaagggtg ttgtgataga cgatgatttc gagtttgatt ttgactaagt actctttgga
     4861 aaagatggta ggaggtaaat atgaagaaga aaattgtgga aggaaatgta ggtgttatta
     4921 ttctaaaaga ttcaactgac tatgctaaat caatggcact aaaagacgaa aaagttgcac
     4981 gcatggataa agatttagtt gaatttctga tggatgatac agaaagatta aaaggggatc
     5041 agtttttgag tttaatgaaa gacaaaggct taaacacata tggtttattt gattataaga
     5101 aattagctat agagtgggta aaagaaggag aaatattttt tattgaagaa tgggaaggta
     5161 ctgagaactt agttcttcat cagtatcttt tgaaagctta atctaagtaa aacagttctg
     5221 actagttatg cttgtcagaa tttcaaagga tgttttccat aaccatcatt attcaaaaat
     5281 aaaggatttg aaaataaggg ttcctttggg aaatctaaag atgaagttaa gagttttgtg
     5341 atagacgatg atttcaagtt tgattttgac tagatttctt tttgcaacgt ttaagagtaa
     5401 acaaggtaag aattaagatt gtgaagattg agagtaaaga aaatagagga cgaatgtatg
     5461 agaacacact atatttattt agaagataaa attgtagatg aaattccggc aaaaagtcga
     5521 gaacaagcta gaaaattatt tattgaaaaa tacaaagaga tcaatggaga tagtgaagtt
     5581 ccgaaagtgg tcgtaacagt tagaaaaagg caaacaaaaa agagaagtac gtttcatgtc
     5641 agccctgata tatataatct tatagagcga catagaagtg aagataatat ttctatctct
     5701 caatatattg ctacagttat tgatgaattg atttcaggaa agtatgacta tgcttttgat
     5761 tttgaggatg aaaaggatta caaaagtgtt gctgtctttc aatctgattt tgagaagcta
     5821 aaaaactatg ctggcaggag aaatgttaat tttgcaagac tactagaaga gttctactcc
     5881 gaagagttgg gagtaggaaa tgaatacaag agagaaactt atgcgaaatt gtctcataag
     5941 ttatcccaag cgcttaaaga agtgacagaa gttaaagcgg aactagatgc taaacttgaa
     6001 gaagtgaaaa aatatcaaac agagaggaag aacaacatga agaatcaagt ggaatttgac
     6061 gaatagaaag aatttgaaaa agcaagaaaa cgctataaca aaattatgaa tgaacttagc
     6121 tatgaacact taacagttca tgaataattg agtgagggta cagaaaaata tacgatcgca
     6181 gatatggtta atgaagtgga aactctttta gcttctttct ttgaaaatgg tcacgtaaac
     6241 gatgaatggc gaaaagaaga acctaaaagg gttaacgctt atattgctcg attaaaaagg
     6301 tttattgata aatataagga gaatagtgac aaattttcta aagataaata aggagagagt
     6361 gtgattacat ttgccagaaa tcgaaggaat attttcgcca aaaataggta aaaaacagtt
     6421 agatttcagc agttttccga gcgtaaatag agattataat ctaggtgatg aggtacagat
     6481 actaaatatt gatttcaaag aactagactt cgctgttgct gtttccaaca aacccaaggc
     6541 attggaacga gtgaaaaaaa tataccaaga gaatgatcaa aatatcaaaa atatgatcaa
     6601 aaagtataga cgagataatt caaaagttga agacgtttta ttcaacggta cggcaaaaca
     6661 tgatttgaat gtttatatgg cattaggagt ggctttgtac tgtaattcaa ttaatcagac
     6721 agatattttg gttaatatcg tgaggaatag ctatcaaaaa atattaaaaa taagtagcga
     6781 aacaaaccct tattatgcaa tgaaatatct tggggataat ttattaaatg ataaaaaatt
     6841 gatgcacaac actgaagagc tgttatctaa tttggctgcg attaactttc tattcaaaac
     6901 aggttctgaa gattatttta tagataacgt actaaaaggt gcttacggaa cagcatttta
     6961 tccgctttac aatatgaaac agcataaagc cgaacaaaag gataacaaac ttgaaattaa
     7021 aaagatgaaa gaactattag gtataggatt tgtaaaaccc aattcaaaag tcactattgc
     7081 ttcgttagca actactaaca atgatgggaa aatagtaaat gggtttgacg attcagatat
     7141 agatatattg tcaaaatcat atttttcttt gtatggagat tttgcagatt tgatgggtat
     7201 tgatagttac ttagtcaata attttgagat caagggtagc gagctgaatg atattgtgta
     7261 tttcgtttta atctctctat atgcaattga tcagaatacc gagtaccgac aaattgacta
     7321 tttgctagtt ttttatagtt tgttatatca gttcgtttta actcggttgt ttaaaaatgc
     7381 taaggaagaa ttgatcctga attctgatta tgaaatagca aaacaaattg caagtattag
     7441 aaaagaaaac aaatctgaag taatcaaatt aagaaaagaa ttaagtattg cgagtaaaga
     7501 aaacggtcgg ttagaatctt tagtcaaatc ggcaaaaaaa gaagaggaac ttttgaagca
     7561 agagattaaa gaattaaaag gaatcagaaa agaacttgaa cagctgaggt ttgaaaataa
     7621 agtattaaag caattgcagg agcaagaaca tagacaatca ttaaatggta aaactgaaga
     7681 gccttcactg tctgaaatga tagcttatct aaaacataaa aacattcttt tagtgggagg
     7741 acatgtaaat tttcaaaata aattaactga actattacca aatattaaaa tgtttgatgt
     7801 aagcgaaaat aatggaaaga tacttaaaaa tttgaatacg tgtgatgcga tttttctata
     7861 tacagattac ttgaatcatg gtctatatta tcgtgttatg agtgaaattt ctaataaaga
     7921 taagatattt tatttggata atcatgtgaa tatgaactta acaattaaac gtatttacga
     7981 tcttttatca cttatataaa gagagaagtg ataaatagga cacaaaattt ggaaagtagg
     8041 taagtcacta tgagagaact aactttatct tctaaggaat tagaaaagaa aactgcttta
     8101 ttaaacgaaa tatttagtgc tgattgtata atccaaagtt taaaagaaag ttcattttca
     8161 aaactaacag atcaggaaaa aatttcttat atgctaagtt tagataatct aggaactaaa
     8221 tatgatgaat cagcaagtag cgataagctt ttgattgaat tagtatcaag tcttagtagt
     8281 tttggaaaaa tgaaaagatt taatgtgata ttagaaattt ttgcttggtt aatcccttca
     8341 tttatttggt ttttttatat tttcatagtt gaatctgagt taatagccaa ggtctctctt
     8401 ggactgttaa ttccgatata tgcattttat ttaataggtt caacaattta ctttaataac
     8461 ttgtatacac gtattcaaat aaaaaagcag ttattacatg aaggattaag tggtaatatg
     8521 ttaaaaagaa ttgcatggga taaagataat aaaacagata ttgagcttaa agaatataaa
     8581 tacaattatt tctcgagatg tatagataga aagttactgt ttaaaaaaga aggattagaa
     8641 tttagttttg atgaagatga atttgaaaaa ttagtgatgg actggcgtaa gaatttactg
     8701 gatacggtac aattctaaaa gcaattgagg tcgaaattcc gatacttgaa tcatgatcta
     8761 tattatcgtg ttatgagtga aatttctaat aaagataaga tatttcattt ggacagtcat
     8821 gtgaatatga gcttaacaat taaacgtatt tatgatcttt tatatgttta taaacattaa
     8881 tgaggtgcta aaattgacaa caataactat gacaaaaaaa atagaagtat atgttgatgg
     8941 atcacaagaa gaaagggatt ccttttttga ttttttttgg aaaaatagta gagaatatgt
     9001 aaaagcgttg aatctggtat ataaacagct aatgtttgaa gagttgataa aagatgcaat
     9061 taaagaaatg gatcaaggtt atgctgagag agaagaaagt attcaaaatc ggattgaaaa
     9121 gttagcatat actgatccaa tagatcaaaa aaaacttgat aaagcaaaag ctgaattatc
     9181 taaattgaga aatgaaaaaa ataaagaagc gagagaaata ttaacgcaag cgatagggtt
     9241 gaagagtcaa acgagaacac gagatgtagc aaaaaaatta gactttgact ttggagattt
     9301 tgttgattcc gcaaatatga aagctagtaa agattttggc aatgatttta tcggaattgt
     9361 gaccggacaa agaacgccta gaatatataa aaatagaaac aaatatggat tattaccttt
     9421 tagaggtcga gatattaaaa tccataaaga tgataagttt tatatttatt tacctaaagg
     9481 ctttaggttt aaagtgaatt taggtagcaa gccaagaaaa gcaagagatg ttgcttcagt
     9541 tttacaacac attatggatg gcgattacaa attaaatcaa agtaatctta tttttgatgg
     9601 aagaaaatta ttttttaatc taacaatttc ttttgaaaaa agctataatg aaatggaatt
     9661 caagaaaggt aatgaattga tcgtaaactt tgcagatttg tgtagcggtg aatgtttaat
     9721 taatgataaa tctgtaatgt cttttggtga tagccaatat ataagaaact tcaaaagtaa
     9781 aattttagca atgaaatcaa aagaacaaag ccgaggagtc ttttctaagg gcggtcatgg
     9841 tcgaaaaaga aaattagatc aagatcgatg ggaagcaata aagaaaagag aaagtaattt
     9901 tgttaaaact tataataatc aatgttctgc aaaaatcgtt aaaactgcta ttcgcaataa
     9961 agctcaaatt attcgtatca ttgaaccaga taaggcttat ggcgaatggg cttactatca
    10021 attgaaagaa caactagtaa acaaaggaaa aagatatggg atagaagtca gaagttagta
    10081 aattaaacaa tcgttgattt ggcaacgaaa tagtgaggga aaatccactc actgaagggt
    10141 aaactccgtc aagttgtgtg accagacgga aggacgaatg ttgttgaggt tttagaacca
    10201 tataaaacag catgtttctc aaatttttag gataagggaa attgctagca gtttgtttta
    10261 gaaccatata aaacagcatg tttctcaaat gagtacttta aattaattga tggcgttcct
    10321 gctttagaac catataaaac aacatggatt taaaacaaga agtaagtcag ttctcctttt
    10381 actttagtaa ggaaaaataa agtattctca ataaaactta aaataagcaa acctttgttt
    10441 taatagctaa tcgaagtaaa acccaaagcc atatgaaccc ctgaatcagc gaaagtttat
    10501 gatgatttgg attactaata gtttaggaat tagatggtaa atctaaatta aacaatcgtt
    10561 gatttggcaa cgaaatagtg agggaaaatc cactcactga agggtaaact ccgtcaagtt
    10621 atgtgaccag acggaaggac gaatgttgtt gaggttttag aaccatataa aacagcatag
    10681 ttctcaaatt gtttaaaatg attgtcaagt taaaaaaatc tgggatcata taaaatagta
    10741 tagttctcaa atatgattag aaaccctatt aaagagcaat attaagccaa cttacttaaa
    10801 tcgtttaatt aagaacaata atctctttta gtcagacttt tagtctgact tttttgtatt
    10861 tccaaaattt attctttaca aaaacgaaca tacgtttgta caattacttg tgaatggggg
    10921 aataaaaatg tttgattaca gtagagaacc ggtgaatgac tattttttaa tcgacatgaa
    10981 gtctttctat gctagcgtgg aatgtattga acgaaattta gacccaatga ctacaccgtt
    11041 aattgtcatg agtagatcgg acaacactgg ttcaggtctg actctagctt cttcacctac
    11101 tgcaaagaaa aaatatcata ttactaatgt tagtagagct actgatttac cttatccatt
    11161 accaaaagaa cttcatattg ttccaccacg aatgaactta tatataaaaa aaaatatgga
    11221 agttaatcag atttttagaa agtatgtcgc agatgaagat ttattgattt attcgattga
    11281 tgaatcaatt ttaaaagtga caaaatcctt aaatttattt actagttcag gaacaagaag
    11341 cgagagaaga agagaattag ctaaaataat caaagatgag attcagaaag aaacaggtct
    11401 aatagcaaca gtcggaatag gagataaccc attattagct aaacttgcac tggacaatga
    11461 agcgaagagt agtaaagaat ttatagctga gtggacttat gagactgtac ctgaaaaaat
    11521 atggaaaata aacgagatga ctgacttttg gggcattgga tcacgcatga aaaaaagatt
    11581 gaatcatatg ggaattatga gtatagaaga tttagcaaat tggaatccct acacaattaa
    11641 aagtcagtta ggtgtaatcg gactccagtt atatttccat accaatggaa ttgatcgtac
    11701 ggatattgct attccaccag aaccaaccaa agaaaagtct tatgggaatt cacaagttct
    11761 accaaaagat tatacgagga gagaagaagt agaactagta gtcaaggaga tggcagagca
    11821 agtagccatt cgaattagac aacacaattg caaaactggt tgtgtacgct tagcaattgg
    11881 tacgtcaatt ttggaagaaa aatcaggttt ctcgcaccag atgaaaatac caattacaga
    11941 taatacgaaa gaattacaaa attattgtct ttttttattc aataagtttt atgaggggca
    12001 ggaagtacga catataggag taacttatag cagattagta tacacagatt ccctacaatt
    12061 agatttattt agtgatccaa gaaaaaagat tgctgaagaa aatttggata ggattattga
    12121 taagattaga caaaaatatg gatttacagc tattatacat gcttcatcta tgttagaagg
    12181 tgcaagaagt attacgagaa gcactttaat aggaggacac gcaggaggat taggaggttt
    12241 gcataatgat tgaatataac gatagaggac gtttaaaatg gtcgggattt tatttgtctg
    12301 atcatactga aagaatcaat gcagacaatg tacaacgtgc taatcataat ttggcaaaag
    12361 aacaaatgac gactgaagag attgcgaaaa tactgagaac tgctgtcata aaaaatagac
    12421 ccgtctgcat tcaaaaagag gaacgaaacg ctgaaggtta ctatccagat gatgtagtag
    12481 gaaaaattat tggatatgac gagcttggtg tatttgtgga agaagaaaaa gttcactatg
    12541 atgaaattag gaatgtttct ttctcggaat tattaaaatg gagtcagata tgaacattat
    12601 taaaaaatac gaattcggtt atattacgta tgaacagcta atagaggaat tatggggata
    12661 tggtcaacaa ttaattaatg aagtggggat tgattgcttt tgtttctata ttgaatccgg
    12721 agcaggatac cataagaaca gatactatat atttccatat ccaccaaaat agtctcttag
    12781 atatttttaa attttctcca aatactttca attattgtga aatatttccc tttaattaat
    12841 caaatttttt ataaaagtaa tatataaaat aaattgcttg aagtattata tttagatatc
    12901 ataatttatg gaagaaaaat taattaaaaa ggatgagatt ataatggggt tactggttcc
    12961 gagagctaat acttatacta tacctttaac gaaacgccaa ttaattgcta aaagatatca
    13021 aaggattact agagccatca atagagagtt ttggaattct gaaagtgata ctgctcacag
    13081 tttatacgta ggttcttatg ggagaggaac ggcaattagt actagtgata tagatataat
    13141 agttgaatta ccgatggcag aatttgacag attcaaaaat tatttatcaa atggcccgtc
    13201 taagttatta caagttataa aaaacgcatt tcaggaaata ctaccaaata gtgatattag
    13261 agctgatgga caagttgtta aaataaattt ccatgatgga atcaaatttg aaatagttcc
    13321 agcttttaat gaaaaagatt attggggtga gtcaaaaggg tttatttatc cagattcaaa
    13381 catgggaggg aactggaaag ctacaaatcc caaaaaagag caagaagcca tgaaattaaa
    13441 gaatacaaaa agtaataatt tattatatgc tacgtgtaaa cattttcgac atgtacgaga
    13501 tacagaattt acgagttatc atctttcagg aatagtaatt gacagtttcg tatatgaggc
    13561 tatgggaaat tggaaattcg ttgaaaataa cagtgggggt caaaacatta gttctgtatc
    13621 ttatgagaca gctttattag aatactataa ctcacataaa gttatgggcg gtttaaattt
    13681 atactctcct ggaagcaatc aatttgttaa ttctgatagt agtatcatat gtttagaaaa
    13741 agtattaaaa aaaatagctt tataaagttt tatggaggaa caacatggga gacgaaaaaa
    13801 agcgcttgga agttcaatta cgtgaagcat atggacgagt aacgtatact tacaccactc
    13861 atttaaagca agccgataat attatttctg acaataaaat tttaaggtgt cttcaaattg
    13921 gtttgtcagc ccttactact ggaggggtac ttagtaccat tattactgat aatagtgagt
    13981 taacctttgt tgctggatta tgttcaacaa tttctcttgg attaaactta tactttaaga
    14041 attttgatct tgctgaagaa gctaaaaatc atcaaattgt tgccgataaa ttatggttga
    14101 tcagagaaga atacgtaagc ttactaacag atttaaatcg tttaagtgtt gaagatattg
    14161 tgaaaaaaag agatcaatta atgaacgaaa ctcatgaagc atataaaaat gcccctaaaa
    14221 caaatagtaa aagctatgaa tcagctcaga aagcattaaa atctgaagaa gagcaatttt
    14281 ttacagaaga ggaattggat aagatgttac cagagcatct tagaaaaaag agttctaaat
    14341 attgaactct ttttttatgc ttaaaattct cttgtaattt ttctattcat ctatatttaa
    14401 gaagaaatat gatgatagaa acatctccta aagccaccgc aagccgttct aagcatagct
    14461 tagcccgaca ttgctagata tgctcatctc accatgaacg tttcctaaag ccaccgcaag
    14521 ccgttctaag catagcttag cccgacattg ctagatatgc tcatctcacc atgaacgttt
    14581 cctaaagcca ccgcaagccg tcctagccat tgcctagtcc gacatcgcta gattagtgca
    14641 tctcgccata aaagttttct aaagccaccg caagccgttc taagcatagc ttagcccgac
    14701 attgctagat atgctcatct caccatgaac gtttcctaaa gccaccgcaa accgtcctag
    14761 ccatcgccta gtccgatttt gcttgatcgg ttccatttct gtttatttag tgggtcaaca
    14821 ccgtaatctt aaatagccat cgcctattta agattactag gtctgctttg aaggtaaaaa
    14881 gtctttcatt cttcaagact tttaggcttt caagctacgc ctgaaagcat tgaaattcat
    14941 cgctctttat ttggttttgc catttataat tccttacgcc cattatcttt ttcgcctgtc
    15001 ataccttgtc agaagtgttt agagcttatc tcatctttgg attaatacaa gtggcgtaaa
    15061 ttattttcta aacgcaagcg ttacgaaaat aatttactta aacacttgta ttaatccggc
    15121 agataagaac gcattctaat cactcccgac aaggcaagac aggcgaaaaa gataaataaa
    15181 tgaacgaaag gaagaaacat aaaatgcaaa accaaatagc gatgaagaaa aaaccacctc
    15241 cctctaaaac aatccaaaca aaaaagaatt ttgaaaaacc aaaaatcaaa aacagaaaga
    15301 agcgttcaac atgagagata gaattttaga agttaatcaa gaaatggtaa acaagttaac
    15361 aaatatcagt gggaactatg aaaagtacga tggtacttta cttgataact atatttttca
    15421 cgatacacaa aatatcagaa ttggcagaag taaaccgaga gcgttcattc tcatcaaaga
    15481 gaaatatttg aatgaatgga atagcaccta tgaaatggtt atgactgata actttgaaaa
    15541 ggtattggat ttcagaaatg ctttgttggg ttctgatatg ggaaatagca gtcttgaatc
    15601 tattgaagtt gaaaacaaga ccgagaatga aggtgaagga ttgattaaga atgtcttgaa
    15661 aatcgaacaa aaatatatca gtgaagatag aagtttttat agagtcacaa gctcggttgg
    15721 tctagcaaac tttgctacta acttaattgg aaacaatgct agtgaatctt tgctagtgat
    15781 gtgtctgaat acaaagaatg aggtcattgc ttatagcgaa gttttcaaag gtggaattaa
    15841 tcaatcagta gcgataccaa gagagatttt tcaactagct ttgctaaaca attcagcaaa
    15901 aatcgcagta tcacataatc atccgagcgg atatgaattt ccaagtgaaa atgacaaaag
    15961 ttttactacg aatttgaaaa acgcaggaaa aacaattggt attgaattgt tagaccatat
    16021 catcgtaaca agtaaaaaca caagctatta ctcatttcaa gaaaatggtt ctttataaaa
    16081 attagagaaa agaggaaaac aagatgggtg aaagaacaca agcgttaatt acagtcaaat
    16141 atggtaacag caaaacgaaa gcaagcgtgt caattcatta tcagtgggga tatggtcgat
    16201 acatgttgat ggacgttttg aatcaaggaa tatatttaat caataaagca tatgacttac
    16261 gagatgaatc aagagaagaa ttagcaaaag gaatctttga tagaagtaca ggagttatca
    16321 attttgtcac ctatgaatct ggagtgagtg cttatgatga aacagggttt ggtgggcgct
    16381 atgaacctta tcaagaaacg attgaagatg tgatgaagtt ttcagataac aatgatggct
    16441 atgctcattt agagatggtg ttcgatgaaa atggatttag tctagatgat aaaaccagat
    16501 tgcgattgtt tgattttgat ggtcaacaga taggactaaa aaagttttgt gaaagcggaa
    16561 aagagtttgc tacgaaagat tttattaagg gatacagatt attgctagaa aattatggaa
    16621 taaacctaga agaagagagc gtgaaataag tgtttgaaaa aagaaaagac cagttcccta
    16681 atttagaagc gaaaagtcaa aaagtgattg atggtgaaat gattgaatta ttccaaaaaa
    16741 gttatggaac catagaaact accgcaagtt gtaaatacta ctttcaagga aagagaaaca
    16801 cgtttaaagg ctttgccgat tctgatgaag aattggcaaa gaaaatcatt gattggcttg
    16861 tcagcagtga acacgtagca agagaagata ccgttagaac aacgattaat ggggaagtcc
    16921 taacaggtac tagatgtgtt tgttgtaatc atgaatttgt agaagatgaa ggttgctacc
    16981 gaatcaatga atatggtgat tttatttgcc agagttgcca cgagatagaa tttccaaccg
    17041 aaagaagttg gtttgaatac atgctacaag attatgagat ggaaaaagaa aatggtgaag
    17101 tagttttttg taccaaagag gaattgagta agagaagcga tgatgaaatt gaagattggt
    17161 gtgtgtggtt agtaggggca gatgattgcg ttgcatatta cacaacagca gaataggagt
    17221 gtgaatcagc atggaaggaa tggattttct agatcatgaa gatttggttg attttggtta
    17281 tacatggaaa ggaatggtag gtattagcag aagtcttgct aatgcctttt acgaaagaaa
    17341 ttatgcagtg tatgttcttt atgatgacga tacagaaagc cttgttgacg aggaatataa
    17401 attggattta gagaatgttt tatatggaat agaaaaggaa gatttagcaa aatatatttt
    17461 ttcatggttg ggtcaataag tgaaaggaag atagaaacat gacaaaattt aaaagtaagg
    17521 gtatgcaatg gtgttcttat tattatgttg ggaatgatga acagcttttg agaaaagccc
    17581 aacaaaaagg ttatccagat aagatgttaa aacagattgg ctattacacg ccagaagaga
    17641 ggatagaaaa agaatcttgt gaggtacttt ttgatagtga acagctatta gttttgttaa
    17701 ctcaaaataa attaatttgt caatttgaga ataattaata tggggtgaat aaccatgaat
    17761 gagaataaga tggtattaag tgaatacgca agattgagaa ccattaattg gttgaatggt
    17821 atgcaaagta gtggcgcttt tgatggattt gatgaagaga atatggactt tgaaagttta
    17881 tcgaatgagg atattagata ttattttatc gaatggtatt ttacagaacc agatgaagag
    17941 gtggaagatg aacaagaatt aattttagaa cgtcaaagta ttttatgcag tgaacaagat
    18001 agtaagaggt tgtatggttt atatgacttg caactgaatg gattaaaagc gcagtacgtt
    18061 gctgatagtt tcgatgatat ggtaggacag ggggcagata gggttgtcac ttattcagaa
    18121 gatgatgaag aggaatggga aaactattca gatgatgaga tatgctttaa tgatgggtat
    18181 atgcctattg aaatcaccga agaagaatat gataaagtgt ccgatagtga tgagattggt
    18241 atgtgtacgg ttgtaagtgg attggatata gatgtccaaa gagtagaggt tgcataccag
    18301 aagatgaaag aacgtataaa aagtatagta gaatcttgat ttaattggat tgtttgcaaa
    18361 gtatctaatt aagagtataa tataatcata aatgtagtta atggatacaa taatgagtat
    18421 attatactta aaagaggtga acgaaatgaa ggtaaaaaat ccaactgaaa aaagcagaat
    18481 ccaagtcgga atagacaaga atttaaaaga gaacgcagaa atgatattgg aagagctagg
    18541 tttaaatcct acaacagcaa tcacaatcct ttataagcaa gtggtcgcta gaggtgagtt
    18601 tccagtagag ataaagctaa gtgaagagga aaagcaagga atcagattgc aacagctaac
    18661 taaggatatg ccagttgatg ttctagatac agatgaaaag ttagaagagt ggttcaatga
    18721 agcctaatga gatagtaacg gtctatgttg catttacaga taaaaatggt ggtaaaagaa
    18781 gacctatttt ggtggttagt gataaagaag atagagtaga attttttgga atcacaagtc
    18841 aatatgagaa gaaatcagac caaataaaga gagtgtattt tcctattgca gaatgggaaa
    18901 aagcaggact taaaaagcaa tcatgggttg atgtagggtc tttaaaggct attcctaaaa
    18961 gccgagagaa catatcattt aaaaaggttg gtatgctatc agctagtgat acgaaaaagc
    19021 taaataggtt tatcgagaga ttacaaagaa aagtctaaca aggcttttct ttttttgatt
    19081 atatgtatat taagatatac gtttgtataa acgtatttat gtatataaaa ataaacgtaa
//
LOCUS       DAIGUC010000055        19013 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.055, whole genome shotgun sequence.
ACCESSION   DAIGUC010000055 DAIGUC010000000
VERSION     DAIGUC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.055"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(22..252)
                     /locus_tag="NOB46_002169"
     CDS             complement(22..252)
                     /locus_tag="NOB46_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059089.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(688..1254)
                     /locus_tag="NOB46_002170"
     CDS             complement(688..1254)
                     /locus_tag="NOB46_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI1059090.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1254..2210)
                     /locus_tag="NOB46_002171"
     CDS             complement(1254..2210)
                     /locus_tag="NOB46_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCI1059091.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2210..2866)
                     /locus_tag="NOB46_002172"
     CDS             complement(2210..2866)
                     /locus_tag="NOB46_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI1059092.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3236..5254
                     /locus_tag="NOB46_002173"
     CDS             3236..5254
                     /locus_tag="NOB46_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI1059093.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5324..5530
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5681..8095
                     /locus_tag="NOB46_002174"
     CDS             5681..8095
                     /locus_tag="NOB46_002174"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCI1059094.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8443..9996
                     /locus_tag="NOB46_002175"
     CDS             8443..9996
                     /locus_tag="NOB46_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI1059095.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10377..12161)
                     /locus_tag="NOB46_002176"
     CDS             complement(10377..12161)
                     /locus_tag="NOB46_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059096.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12176..13897)
                     /locus_tag="NOB46_002177"
     CDS             complement(12176..13897)
                     /locus_tag="NOB46_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059097.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLTGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13997..14758
                     /locus_tag="NOB46_002178"
     CDS             13997..14758
                     /locus_tag="NOB46_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1059098.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15725..15993
                     /locus_tag="NOB46_002179"
                     /pseudo
     CDS             15725..15993
                     /locus_tag="NOB46_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16665..>19013
                     /locus_tag="NOB46_002180"
     CDS             16665..>19013
                     /locus_tag="NOB46_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059099.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEF"
BASE COUNT         6245 a         3374 c         3816 g         5578 t
ORIGIN      
        1 tctcattaaa aagcataacc attactccga tctgttttta aaattagttt ctacctctaa
       61 tatatatcga gtttttattt tgccttcaga gaatactgtt tctttttttg cagttacagg
      121 ttgtttattt tcggaaaaag ctaatatagc taagattgaa acatccatct ggaatttatc
      181 ttttttactg ctttgatcat aaaagtctgc atattcatca ctgatatttt ttctaataaa
      241 ttcttccatc ataaaaatca cctcaaaacg attatacgaa cttacgttct tgttgtaaag
      301 cgatatttga ggggcaaaaa aggggcataa tttgactgat attaagttag ctattgatat
      361 atgaatgaca tacaaaaata taaaatcttt taaaaatgct tatatatcaa tgtttttgcc
      421 attcttttat atatctgtta tatgtcaaaa aaatgtgttc aatttcaatt tgtatttgaa
      481 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
      541 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
      601 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
      661 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
      721 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
      781 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
      841 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
      901 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
      961 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
     1021 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
     1081 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
     1141 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
     1201 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
     1261 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
     1321 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
     1381 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
     1441 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
     1501 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
     1561 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
     1621 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
     1681 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
     1741 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
     1801 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
     1861 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
     1921 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
     1981 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
     2041 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
     2101 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
     2161 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
     2221 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
     2281 acagccaaga aagactgagt aagtagccgc cgatgatatc agtaggaaaa tgaacgccca
     2341 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
     2401 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
     2461 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
     2521 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
     2581 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
     2641 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
     2701 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
     2761 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
     2821 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
     2881 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
     2941 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
     3001 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
     3061 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
     3121 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
     3181 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
     3241 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
     3301 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
     3361 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
     3421 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
     3481 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
     3541 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
     3601 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
     3661 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
     3721 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
     3781 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
     3841 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
     3901 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
     3961 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
     4021 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
     4081 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
     4141 ggaaaatggc tcttcgacga ataattccgg taacaatacc aactcttcag gaaatgctgg
     4201 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
     4261 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
     4321 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
     4381 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
     4441 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
     4501 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
     4561 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
     4621 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
     4681 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
     4741 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
     4801 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
     4861 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
     4921 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
     4981 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
     5041 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
     5101 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
     5161 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
     5221 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
     5281 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
     5341 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
     5401 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
     5461 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
     5521 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
     5581 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
     5641 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
     5701 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
     5761 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
     5821 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
     5881 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
     5941 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
     6001 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
     6061 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
     6121 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
     6181 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
     6241 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
     6301 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
     6361 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
     6421 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
     6481 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
     6541 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
     6601 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
     6661 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
     6721 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
     6781 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
     6841 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
     6901 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
     6961 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
     7021 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
     7081 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
     7141 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
     7201 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
     7261 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
     7321 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
     7381 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
     7441 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
     7501 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
     7561 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
     7621 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
     7681 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
     7741 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
     7801 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
     7861 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
     7921 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
     7981 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
     8041 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
     8101 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
     8161 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
     8221 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
     8281 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
     8341 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
     8401 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
     8461 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
     8521 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
     8581 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
     8641 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
     8701 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
     8761 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
     8821 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
     8881 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
     8941 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
     9001 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
     9061 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
     9121 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
     9181 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
     9241 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
     9301 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
     9361 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
     9421 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
     9481 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
     9541 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
     9601 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
     9661 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
     9721 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
     9781 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
     9841 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
     9901 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
     9961 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    10021 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    10081 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    10141 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    10201 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    10261 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    10321 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    10381 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    10441 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    10501 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    10561 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    10621 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    10681 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    10741 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    10801 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    10861 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    10921 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    10981 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    11041 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    11101 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    11161 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    11221 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    11281 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    11341 aaggcgagtt gattaatgaa acgaatggcc ggatagatag cacagttcat aaattgagca
    11401 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    11461 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    11521 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    11581 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    11641 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    11701 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    11761 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    11821 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    11881 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    11941 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    12001 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    12061 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    12121 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    12181 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    12241 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    12301 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    12361 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    12421 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    12481 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    12541 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    12601 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    12661 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    12721 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    12781 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    12841 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    12901 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    12961 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    13021 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    13081 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    13141 aagcataaac gattcccgtg agcaaaaaag caattggagt gacccaagca aatattcggt
    13201 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    13261 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    13321 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    13381 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    13441 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    13501 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    13561 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    13621 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    13681 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    13741 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    13801 gtacacctaa tgtaccggcg atttctaaac agatcatcac aaaggtaagg agagcgagtc
    13861 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    13921 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    13981 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    14041 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    14101 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    14161 tttttataga aaattagata tacctatcaa acagatgaag aatttatatg gaaaaacatt
    14221 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    14281 gatgaaacaa aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga
    14341 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    14401 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    14461 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    14521 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    14581 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    14641 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    14701 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    14761 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    14821 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    14881 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    14941 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    15001 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    15061 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    15121 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    15181 aatcaaatag tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt
    15241 tttgcttata aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag
    15301 aaaaatcaca aaggttattg ttatttttat atattctttt taagaatgat tgttttttta
    15361 tagaaatttt aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata
    15421 ttatagaagt tgactggtag tgatttattt ttcgtcgttt tataaaaatg ttattttttg
    15481 gaaaaattca caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta
    15541 tgactaatat aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg
    15601 gaatcaatga aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat
    15661 agcaatacat cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac
    15721 aacaaaagga ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt
    15781 tattctatac aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa
    15841 tatatggtac agaatataga aattattgac attacagaaa atgatgaaga tttaatacag
    15901 attgtcacta tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg
    15961 attaaggagt tgatggaaga cgatacaagt taagaaagtg aaactacgcc caaataaaga
    16021 gcaaaaagag taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt
    16081 ttattagtaa tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg
    16141 tttagttgaa ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc
    16201 caagtattct aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt
    16261 gatgaaggtt aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc
    16321 aacgatttag tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa
    16381 taactattag ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca
    16441 taattatggt taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac
    16501 agaagacaat cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa
    16561 ccgaaaatac gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta
    16621 tcgggtacct tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc
    16681 ataaactgtt aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa
    16741 cggttctagc tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc
    16801 aagaggaggc tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc
    16861 taaatgcatt ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca
    16921 atgattacga acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg
    16981 caagaagcgg tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa
    17041 gcacaagtga gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag
    17101 aagaaagctt aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg
    17161 aatctcagat tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc
    17221 gccccacttt gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg
    17281 gcgatattct tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct
    17341 taattgagtt cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt
    17401 accaagaagg cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag
    17461 ccgctcagtc gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta
    17521 ctgagccaaa taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg
    17581 aattttcaat tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct
    17641 ctagagaaat cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga
    17701 ccaacagtaa taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag
    17761 tggttaccga tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt
    17821 ccactggaaa tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag
    17881 gtgaagcaaa cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta
    17941 ataaggaaac gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt
    18001 ttattgaata tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg
    18061 atgggttttc tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact
    18121 accgcttgag aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca
    18181 aaaatgttat caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt
    18241 ctggaacaag aaatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt
    18301 catttctatc agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt
    18361 tcagtgcgaa taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg
    18421 tagaggcgta tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca
    18481 atcgattgaa tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta
    18541 aaactgatga gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt
    18601 cacaagtgat acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc
    18661 ctgtaggtag ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga
    18721 cggtacatga tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa
    18781 acatccttga tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc
    18841 ttcaaggagc tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggtttaa
    18901 ctacaggaga agatggaaaa ctggcaattg acggtttagc accaggagca tatcagctgg
    18961 tagaaactca agcgccaata gggtatgaat tagatgcgac accaatcgag ttt
//
LOCUS       DAIGUC010000056        17799 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.056, whole genome shotgun sequence.
ACCESSION   DAIGUC010000056 DAIGUC010000000
VERSION     DAIGUC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.056"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(6..1307)
                     /locus_tag="NOB46_002181"
     CDS             complement(6..1307)
                     /locus_tag="NOB46_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI1059100.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(1537..3495)
                     /locus_tag="NOB46_002182"
     CDS             complement(1537..3495)
                     /locus_tag="NOB46_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HCI1059101.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(3672..3938)
                     /locus_tag="NOB46_002183"
     CDS             complement(3672..3938)
                     /locus_tag="NOB46_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1059102.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(4448..6574)
                     /gene="pnp"
                     /locus_tag="NOB46_002184"
     CDS             complement(4448..6574)
                     /gene="pnp"
                     /locus_tag="NOB46_002184"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCI1059103.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(6762..7031)
                     /gene="rpsO"
                     /locus_tag="NOB46_002185"
     CDS             complement(6762..7031)
                     /gene="rpsO"
                     /locus_tag="NOB46_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCI1059104.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            7282..7845
                     /locus_tag="NOB46_002186"
     CDS             7282..7845
                     /locus_tag="NOB46_002186"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI1059105.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(8098..8619)
                     /locus_tag="NOB46_002187"
     CDS             complement(8098..8619)
                     /locus_tag="NOB46_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCI1059106.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(8622..9464)
                     /locus_tag="NOB46_002188"
     CDS             complement(8622..9464)
                     /locus_tag="NOB46_002188"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCI1059107.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(9457..10182)
                     /locus_tag="NOB46_002189"
     CDS             complement(9457..10182)
                     /locus_tag="NOB46_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCI1059108.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            10358..10654
                     /locus_tag="NOB46_002190"
     CDS             10358..10654
                     /locus_tag="NOB46_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059109.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            11222..12814
                     /locus_tag="NOB46_002191"
     CDS             11222..12814
                     /locus_tag="NOB46_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI1059110.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            12827..13567
                     /locus_tag="NOB46_002192"
     CDS             12827..13567
                     /locus_tag="NOB46_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1059111.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            13735..15084
                     /locus_tag="NOB46_002193"
     CDS             13735..15084
                     /locus_tag="NOB46_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI1059112.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(15212..15802)
                     /locus_tag="NOB46_002194"
     CDS             complement(15212..15802)
                     /locus_tag="NOB46_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI1059113.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            15949..17301
                     /gene="brnQ"
                     /locus_tag="NOB46_002195"
     CDS             15949..17301
                     /gene="brnQ"
                     /locus_tag="NOB46_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI1059114.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         5117 a         3603 c         3406 g         5673 t
ORIGIN      
        1 ttcttttatt ctatttttct ttccgtggac tctactttga aataatcgat atgtgcatgc
       61 tggtattcta ataccgtgaa acggaatgat gcaatctcaa tgattgttcc tgcttttatt
      121 tctttatatc ggctagaagc aaagcccgca agtgtagtaa aattcgtttc ttcaaactct
      181 ggaatctcta catgaaaata acgctggaaa tcatctaatg ttagtttgcc ggagatgata
      241 taagagccat ctgactgttc cgctatcaat gcttcgtcca aatctgtctc atctcggatt
      301 tccccgacga tttcttctaa aatatcttca atcgtcacta agccgcttgt ccctccgtat
      361 tcatctttta agatagcaat atgctttccc ttttttcgca tgatcgtcaa taattttttt
      421 atagggatcg tttcagttgt tacgatcggc tcttcaatca actgttctac tgtcagctgg
      481 tcatctttat aagattgctt gatcaaatct ggcaaggtga cataacctaa aacattgtct
      541 tttgattcta agataaccgg atagcgagta tgtccttgtt caatcgaagc ttttatcgct
      601 tctttgacgg tttctgaagc ttcgaatact tgcatggacg tacggtctac ttgtatatct
      661 tttgccaagg tatcatcaaa ttcaaacacg ttttccaaat aatgatattc ttctttggtc
      721 aactctcctt tttcataaga attcaatgcg actaatgtca gctcttcttg agacaatgtc
      781 tcttctcctt cagatacgag acgcacacct aatagcttcc ctagccctgc agctgaatga
      841 ttcaataccc aaataaaagg aaacattact ttataaaaat aatgaagtgg tttaactacg
      901 aacaagacga ccttctccgt attgacgata ctatagctct taggaagcag ttcgccaata
      961 accacatcga tatacgtaac taaaataaat cccagcgcca cagagattgt actgctaata
     1021 gccgaactaa aaggtagttt accgatcact ggttctagta aagccgcgac agatccttca
     1081 ccgacccacc cgatgatcaa accggttagc gtaattccta attgactagc tgataaatag
     1141 ttatctaaat ggtgtgtaac atgaagagct agcttggcgt tctttacatt ttccttttct
     1201 agttgttcca atcttgatcg tctgattttc actaaagcaa attcacttgc tacaaaaaat
     1261 gaagtaattg caatcatcaa aaataaaata atgaaattga taaccatatt ctcccgcctt
     1321 tctctttttc tattgtaccc tttttctaca aaaagattga aaataatgcg tattcatatt
     1381 taggaataaa aaaggagatg cggcattttt cagccacatc tccttatcac ttcaaaatca
     1441 ttgcgttact tgttgctaaa cagctttttc atgacctctg ataaacggtg ttcaagtagc
     1501 tgacattcga cattagttca ggtcaaagcg ctactttcac aaccgctctt tcaaccatgt
     1561 tttccgagta tttccaatga taagcggaac agtttcatgt tttacttcgc tgtactctag
     1621 cccaaaccat gtttctggcg aggtagcgat ttttttgatt gccagttttg cctgcatgat
     1681 ttgacgttgc cattttccta gagttgtcac attggaaact acttcatcaa tcaggacaaa
     1741 ttggaaatcg ccaacttctc gccctggtgt cagagagtat ctttgtggct gttttggcaa
     1801 acggccttgt ttcatcaaat catggatgac ttggcgaaca tatacgttga tttcctgttg
     1861 gaccctgaaa cctaagaaca gattcacttg gacaataaaa tcagtgtcca tcatatctac
     1921 ttgatattct ttcgtatatg gctcatccgt cacttccaca tgaacaaacc aatagactcg
     1981 tgctctttta ggccgtttat ctaaaatcga atagatgaac tgtcggccaa ctttatcttc
     2041 agccatatca ggaaccaaga agaccacatt tgtctgatag attggtaaag aagtatcatc
     2101 acgtaattct ctaagctgcg ggatataatc tctcaaagac acatcctcgg ttgacgattc
     2161 gcgaataatg ttcccttgtt cccaaataaa catcacgact aagatgatca aaccaatcag
     2221 aacggctaca aaaccgcctc ggaagaattt gacaacactt gagataaaga aaacgacttc
     2281 tatcgcaccg aagaaaaagg taactaaata tgcaagccaa cgagaatgcc cattttggat
     2341 aagataaaag taaagcagtg ctgttgtcat caacatcgtc acagtgatcg atagaccgta
     2401 agcagcttcc atatgatgag acgttcggaa tgtgacaacc actagagaac aggcgatcca
     2461 taaaatcaga ttgactgctg ggatatacat ttgcccgata ctgttcccag gatacatgat
     2521 ctttaaccga ggcagcagtt tcaacttgat tgcttctgaa actagcgtaa acgaacctgt
     2581 aatcaatgct tgcgaagcaa tgactgcagc gactgttgca aaagcaacgc cgatcacgat
     2641 ccaactttga ggcatcattt ggaagaatgg attcaggttc ttgatttgct gtgcttcagg
     2701 gttttgataa acattcaaca accacgcagc ctgcccaaaa taattgataa ccaaacaaat
     2761 tttgacgtaa ggccagctca gacgaatatt tcgtttgccg acatgtccaa gatcggaata
     2821 aagcgcctct gcacctgtcg tagccaggaa aatatttcca agaatgaaca agcctaattt
     2881 gttatctgca ctaaaaagca gctggatagc ataataagga ttcagtgcac ggataactgt
     2941 ccagtcttga ctgaagttca ttaatcccat tacgcctaaa aaagtaaacc aagcgaacat
     3001 gattggtccg aatgcttttc cgacaatatc tgtaccaaag cgttggacca tgaataaaac
     3061 aaaaataata actaaagtga taatgacgat cacgttctgg ttattaccga accggtcaaa
     3121 aaactgcgga attcctcgca agccttcaat cgcagtcgtt accgtcacag caggggtcaa
     3181 taccccatct gctagtaagg cagctcctcc gatcattgca ggaatgatca aatatttccc
     3241 accttttcgg acaagtgtgt agagtgagaa aattccacct tcaccatggt tatctgcatt
     3301 caatgcaatc acgacatatt tgattgttgt cagtagagtc aatgtccaaa aaatcaatga
     3361 gactgatccg ataacaaaat caggattgat tcctgacaat ccgccattat cttcaacaat
     3421 cgatttcata acgtaaagcg gacttgtccc gatgtctccg tagacgactc ccatcgctac
     3481 aagcaggcca gccattgata tctttttggt attgtgcgtt gttgccacgt ttttccctca
     3541 tttcttgtta tatggatatc ctttaggtaa gcttgaatga tagatgatat tcttatccat
     3601 gacacccgct ttcctaaatt gcttctaatt atccaagtaa cacactgaag tgtcaactta
     3661 tttgaataaa attattcttt ctttggacgt tctctgatac gtcttgccac aaatgaataa
     3721 agagcaaggc aaaaaattgc acccaataat gctggtatca aataaaaacc gccgagttcc
     3781 ggtcccagtg gtcctagtaa aaattcgccg agccaactac ctaaaaaacc gataatgata
     3841 tttccagata cgcctcccgg gacttccttt cctaaaattg cgccagctat caaacctaat
     3901 ataccgccga taaataacga ccataaaaaa ttcagcatct cctttccctc ctttatccat
     3961 atttctcact tttattttac gctttattca gaaggactcc aaaaatatgc gccaagaaac
     4021 tccagaaaaa aagaagttgt aacaaaagtg ttcagcttat ttccgtagaa gctgcttctg
     4081 gaacaccgtg aatcagaggt tgtgaaatca gcggtttgac ctgagtatta gagaaacaaa
     4141 cggaaaaata gttcctcata ttttgccgtt ttttgagcta atatcgaggg acagctgatt
     4201 gaacatcgtt tattggagag gttgtaaaaa agctgttctg catcaagtaa taagaacagc
     4261 caagtaaaaa cagctcctaa tgtttttaac ttggctggac ttattaccgc agatgcaagc
     4321 ttttgaacac cgtttattcg aaaaaaaagg actgtgacac ggcttttgtc acagtcccct
     4381 tttttcgaat aattattgtc cccctgtcac cttcacgatc acaagtacat tattcctatg
     4441 aattaaatta tttttcttca tttttcgttg aaccatcttc gttcaacatt gcttttcttg
     4501 acagatttac gcgtccttgt ttatcgattt cagttacttt cacaaggatc tcatcaccta
     4561 gtttaacaac atcttcgact ttattgacac gatcgtttgc taattgggaa atatggacaa
     4621 gtccatcttt tcctttgatc aagttgacga atgcaccgaa tttttcgata cggacaactt
     4681 tccctagata aacttcacca actttgactt ctttggtcaa atcttcgatg atcttgatag
     4741 cttttttgat catttctgca tcagctgaag caatacttac ttttccatct tgatcgatat
     4801 cgattttcac accagtttca tcgatgattc cgttgatcgt atcgccgcct ttaccgataa
     4861 catctttgat tttagcaggt tcgatctgga tcatttcgat ttttggtgca tattggctta
     4921 attcttcacg tggagcagca atcgttgaag tcaattcttc taagatttcc atacgtgctt
     4981 gttttgcttg agttaatgct tcagttagga tttgttctgt gattccttga atcttgatat
     5041 ccatctgtaa agcagtgata ccatcttttg taccggcaac tttaaagtcc atatcgccaa
     5101 gatgatcttc cagcccttgg atatcagtta ggatcgtata gttttcacca tcagaaacaa
     5161 gtcccatcgc aataccggcg actggcgctt tgattggtac acctgcatcc atcaatgcta
     5221 atgtgccagc acagatactt gcttgggaag aagaaccatt tgattccaat acttctgcta
     5281 ctaaacggat cgtataagga aattcttctt ctgaagggat tacttgtgct aacgcacgtt
     5341 cacctaatgc gccatgtccg atttcccgac gccctggaga gcctgcacgt cctgtagaac
     5401 caacagaaaa ttgagggaaa ttgtagtggt ggatgaatcg tttgctgact tccaccccta
     5461 aaccatcaat gatttggtgc tctcctagag gtgcgagtgt acaagctgat aaagcttgtg
     5521 tttgtcctcg tgtgaacaaa cctgatccat gtacacgtgg caataagctg acctctgatg
     5581 acaatggacg gatttcatcc aatttacgcc cgtcaggacg gatcttatcg atggtgatca
     5641 attcacgtac gacatctttt tcaagatctt ctgtgatttg tttaacttct ttcaacaagt
     5701 gatcttcatc ttcatgacct gcaaatttct cagcataagc ttcgcggata tcgatcttca
     5761 cctgctcgat attatcttcg cgagcaagtt tttcttcagt cattactgct gctttcattg
     5821 tagcgtaaga agcatcaaag atttcttttt tcaatacttc atcaacttgc agtaaagtca
     5881 cttccatttt ttctttccct actgcttgaa cgatttcttc ttggaaagca actaactctt
     5941 tgatagcgtc aaaaccaaac agcaatgcac caagcatgtc ttcttctgaa acttctttcg
     6001 cgccgctttc aaccatattg atggcttgtt tcgttccggc aacagtcaat tcgatatctg
     6061 tttgttctgc ttgttctact gttggattca agacgtactc gccatttaca cgaccaactt
     6121 ctacgcctgc gattgggccg tcaaatggga tatctgagat tgatagtgct aaagaagaac
     6181 ctagcattgc tgccatagct ggcgagcagt ctgtttctac actcatcacg atgttcgtta
     6241 cttggacttc attacggaag ccttctgcaa acatcgggcg aattggacgg tcgatcaaac
     6301 gggcagtcaa tgttgcttcc gtacttggac ggccttctcg tttgatgaaa cctccaggga
     6361 ttttccctgc tgcatacatt ttttcttcat aattgatcgt taatgggaaa aagtctgtat
     6421 cttttgcttc tttagaggcc acagctgcac ttaagactac tgtatctcca taacggacta
     6481 aaacggctcc gtttgcttgt tttgctagct gaccgacttc gatttgtaag ggacggccgc
     6541 cccatgtcgt tttgaatact tgtttttctg acataacttc tccttttcct tctcgtgaaa
     6601 gcaagacgct actaaacaaa tgaaaactgc cgaaagccgt cttttgagca gctttcattt
     6661 ggttagtagg agtccatcta gcttgatcac ggaattttac ttaattgata tacgagtaaa
     6721 aaaagtgaga ttcatgtgaa tcccactctt tttgactaaa attaacgacg caagcctaaa
     6781 cgtttgatca attcgcggta acgttgaacg tcagttttac gtaagtaagc taacaagtta
     6841 cggcggtgac caactttttt cattaggccg cggtatgaat gatggtcttt tttgtgcacg
     6901 cgtgcatgtt cattcaagtg gttgatttct tcagttaata cagcgatttg tacttctgga
     6961 gaaccagtat ccccttcatg gcgagcgtat tcgttgatga tttcattctt gcgttctttt
     7021 gaaattgcca tttctttcac ctctttcgat tattcccctg cgactgagta aaacgttggt
     7081 gattcgctta accaagtggc aggtcatgtg cctagagcac acagctatac tttacctgaa
     7141 accgggttga aaatcaagta gttaatcatt aagaaaaggt agttttcaaa caatcttact
     7201 actacttttc catttttgtg gtaaactata atgcgaaaat agacttgaaa cacagtcttt
     7261 taagaaaggg gtacatattc catgattaca atggatgata tcattcgtga aggaaatccg
     7321 accttacgcg aagttgcaaa agaagtttct cttccattaa gcgaagaaga tatctcttta
     7381 ggaaaagaga tgcttgagtt cttaaaaaac agccaagatc caatcaaagc tgaagaacta
     7441 cacttacgag gcggtgttgg cttagctgct cctcaattag atatttctaa aagaatcatt
     7501 gctgttcacg taccaagtcc tgacccagag gcagatggac cttctctaag tactgttatg
     7561 tataatccta aaattttgag ccattctgtt caagatgctt gtttagggga aggtgaaggc
     7621 tgtttatctg ttgatcgaga agtaccagga tatgttgttc gccatgccaa aatcactgtg
     7681 tcttattatg atatgaatgg tgaaaaacac aagattcgtt tgaagaatta tgaatcgatc
     7741 gtcgttcaac atgaaatcga ccatatcaac ggtgtgatgt tctatgacca catcaacgat
     7801 caaaatccat ttgcactaaa agaaggcgta ttggtgatcg agtagagaat tggcaggttc
     7861 cttcgatact atgctacaag aaagctttat aaaaaagggg agtgctcaaa agctgcactt
     7921 ccctttttta tgtttctcca ctaatcgaaa tttagataga catctagaaa tcgcaattcc
     7981 aaaaaattct gtgtattgga tacgcatctt ttcttatttt ttcttatttc ttccatatgg
     8041 gtgtttatct cagagatgat agaatagttt ctaggataaa aagtagcagc tacgatgtta
     8101 tccttcgtag aggattcctg cttcagctag tttttgtttg atgtttttca gcatatgctt
     8161 ttctgggtag cggatcgtat gcagatggat gccgcctgtt aattcggata acaaagtagc
     8221 attacttttt tgataacgtc tcataaagga atcgatatct tgtggcgttt tgatgtgcaa
     8281 agttcctgct aactcaccgt aaaggggatg ttccacaatt acatcaatga tttcaccacc
     8341 attttcaacg attagtctca gttcttcttc tgtttgatct tttccatgct ggacagcgat
     8401 tttactgatg tgcccagtat tggtttcttc tgtttcgagg atataacctc ttgctgttgc
     8461 cacgatactt ttacctgcag ctcgtagtaa agcaatatcg cctacaatga tctgacggct
     8521 gactccaaaa gttttcgcaa acttgctagc actcactggt ttttctgtat ttgccaaggt
     8581 ttgcatgatt tgttttcgcc gtgtctctcc ttcgatcaca cttattcctc cttcattttg
     8641 ttttggtatt cgcgcgagtg tttcatcaaa tcaacatacg tgtctgttat tgtttcctta
     8701 tatcccttat ttttcagcag actaacaact ttatccaata cttgctgctc tctttttgca
     8761 tcataaactg cttggttttc ttcttttttc acttgtccta ttttagttac cgtatccatt
     8821 cttttttcta ataaagcaac caactctcga tcgatcatat cgatcttatg acgtaatgtt
     8881 tcaagagact cttctgttag ttcttcctct actgtcttga tgatacgagc aggatttcct
     8941 gcaatcacta cattgtcggg aaaagatttg gtcacaaccg aacctgcgcc gactactacg
     9001 ttgtccccta gagtgacacc cggcgtgacg ataactcctc cgcctaacca aacattatta
     9061 ccgattttaa tgggttttgc gtactccaga ccgctgttac gtttcactgg atgtagtgga
     9121 tgcgtcgccg tgtaaagctg gacattcgga gcgaacatgc agttatcacc gatttcaatc
     9181 gtgctgacat ctaaaaatgt acaattgaaa tttgcataaa aattctcccc aacaaatata
     9241 ttatatccgt aatcaaaatt gataactggc tccatataga tttttttccc tgtacggcca
     9301 aaagtctctt tcaacaattg ggatcgcagt tccgctgatt ctgcttggtt gatgatttgg
     9361 ctttgacttc ttgcaaacat acggtcggca accagctcag gatcattggc aaaataaagc
     9421 tcgcctgcaa tcattttttc tttttcggtt ttgaattcag tcataatctg ctcctaattc
     9481 ttgtattttt ttgaaaacaa ccgctccgtc ttcttgaata aacgtataag gctccgctaa
     9541 ataaacaggc gtttgattga ttactaagat tttggctgac ggctggcgaa actgtaccag
     9601 atcacaaaac ggatgaactt gaaaactcgt tccaacaatg acgatcagct ctgcttggct
     9661 gacggcataa gccgcctgct ccatgactcc atcttgaaac ccttcaccat ataacacgat
     9721 gtctgggcgt atttgtcctc cgcatgcttg atgtttgtcg ctgtgaagat attctttcca
     9781 gtctaccgtt tgttgacatt ttcgacaatg acattgatac agactcccat gaaaattgac
     9841 gagttgcggg cttttagcct ttgcgtgcaa accgtcgatg ttttgggaaa caacccaaac
     9901 atttttttct ttcgctagat gtgctatttc caaatgaatg atattgggtt ttgcttcagg
     9961 atgataaatc tttttgacaa attgatagaa tttatccggt tcattcacca ttgcttgatg
    10021 actcagcaag tattccggct gctccatccc gtggtagatt cctgacaaag atcgatagtc
    10081 tggcactcca gaaggtgtgg atacccctgc accggtcaaa aatgtaattt gctgataagc
    10141 taatatctct tttgctgctt cgtctactgt taattgtttc atgttttgtc acctcacttt
    10201 ccattatagc ccatactcga acaaatttat tgttgaaaag tcagaaaaat gggaataaaa
    10261 aagtgttatg ggcatttgag caatttatca caatgttcac tgacaaaaga atgaaaacgt
    10321 gttacaatac tgctgtataa aagtgaggtg aatcgatatg ttaccattct ttatttattg
    10381 gggcgttatt ctggcttgta tcgcctggtt agcgttaagc gtttatttct ctgtttttta
    10441 tcttgtacgc aaagaaaatg gaaatctttg ggcttttgct ttattcaacg tgattgccgc
    10501 aattgtttta gccattacat tagccgtata tcgaacatgg ggctggggaa tcacccaata
    10561 ctcaagtttg atttatctaa tattagccat ttatggcgtc gttgttcttt tgcaagcgat
    10621 cctaggacgt gagccaaaga aagcggcagc ttaaatgatc gagatggaac tggacacagg
    10681 aaattttctg ttctagttct ttttttattg tattacatac atttttgtgt ataattatac
    10741 tatcgtttgc aatggataga tgattcacat tttgattgtt ttttcggtaa aagtaaagat
    10801 ttctatattt atcagtattt tttcaaaaac cagcagttat agattgacaa agcctctcga
    10861 gtatcgtaaa ctttttttgt ataaataact gaatacgaga tgcctcaatc aatgaggtag
    10921 aggtcgcgag aatcattaac cctgtggagt gaagcaaaca tggagaagca ggaataggga
    10981 ggatcgccga aatgtgcact tttttgcttg gagtgtatgt tgggacgcaa gttaagagct
    11041 tgcggactgt cttagcagtg atgctaagtt gcgctatgtt ttgtgagagg tttatcacct
    11101 tatggaattt tagcggcctt tttatatcta taaatcggtc gctttttatt ttttcagata
    11161 aagctttacc gcatttcatc tagaccgctc gtgtatcata taatcagaaa gggagaaaaa
    11221 aatgaaaaaa aatatggttt cagttgccgt actatttgct tttgtcttct cactattcag
    11281 tgtgggatct ctggcaaatg cagatgaaaa aacaccgagc gatgagtttc gcgtaggtat
    11341 ggaggctggg tatgcaccct tcaactggtc tcaacaaaca gatgagaata atgccttgcc
    11401 aattcaaggc caaaatagtt acgccggcgg ttatgatgtt caaatcgcta aaaaagtagc
    11461 agatggttta gggaaaaaat tagtcatcgt ccaaacgaaa tgggatggtc tggctcctgc
    11521 ccttcaatca ggcaagatcg acgcgatcat cgccggaatg agccctactg ctgaacgacg
    11581 aaaagaaatt gattttaccg atccttatta cgaatcacaa ttagtagtag tagttcaaaa
    11641 agatagcaaa tatgcaaaag caaaaagttt agcagatctt tctggagcaa agatcactgc
    11701 tcagttaaat acattccact atactgtgat cgatcagata ccagatgtgc agaaacaaca
    11761 agcaatggat aatttctcag caatgagaac agctttagct tctggaatga tcgatggtta
    11821 tgtcagcgaa cgtccggaag gtgtaacggc aactagtgtg aacaaagact tggaaatgct
    11881 tgaattcagc ggtgcagatg gcttccagac aaacccggaa gatgttcaga tttctgttgg
    11941 tatgcgtaaa ggcgacccgg atatccaaaa agtaaaccag attctttctg gcatctctaa
    12001 cgatgaacga accaaaatta tggaccaagc agtcaaagat cagcctgctg caactgatag
    12061 tgaagaaaaa cctggcatca tttctgattt cactacgatt tggaaacaat acggcaatat
    12121 gttcttacga ggtgctggac ttaccttgtt catcgcattg atcgggacag ttgtcggtac
    12181 tacacttgga ttactgattg gtgtcttccg ttcggtacct gaatcaggaa atgcactgac
    12241 tcgcttcttc caaaaaatcg gaaatgcact tctttctatc tatgtcgaag tattccgcgg
    12301 aacaccgatg atggtacaag caatggtcat cttctacggt ctggcactcg cttttggcat
    12361 ttcattgaac cgaacgattg ccgctttgtt tattgtctct ctcaatactg gagcttacat
    12421 gacagagatc gttcgtgggg ggatttttgc agtagatgaa gggcagttcg aagctgcgca
    12481 agccattggt atgacccatg gccaaacgat gagaaaagtt gttattccac aagttttacg
    12541 gaatatcttg ccagcaacag gaaatgagtt tgttatcaat atcaaagata cagcagtttt
    12601 aagtgtaatc ggcgtagctg atttgttctt ccaaggaaac tctgcttccg gtgcgaattt
    12661 ccaattcttc caaacattta cgatcgtcgg gatcatctac ttagtcatga cctttacgat
    12721 caccagaatc ctgcgggcgg tagaaaagaa aatcgatggt ccttcagctt ataccaagct
    12781 tgaagaaatc gacaattcaa atttgcagga ataaggagga agaatcatga atgaaaaaat
    12841 tattgaaatc aaacatctaa gaaaaagctt cggtgaaaat gaagtattga aagatatcag
    12901 cgtaacagtc aataaaggtg aagttgtgac gatcatcggt tcttccggtt ctggtaaatc
    12961 tactttcttg cgctgtatca atttactgga aaaaccaaca ggcggcgaga tcatttataa
    13021 tggagaaaat gtattagctc ctaaatataa tttacctaaa tatcgaacga atctaggtat
    13081 ggttttccaa tccttcaacc tgttcaacaa tatgaatgtc ttggaaaact gtatgtctgg
    13141 tcaaacaact gtcctgaaac gagataaaga aactgccaaa aaagtagcaa tcgaaaatct
    13201 ggaaaaagtt ggtatggatc gttatatcga agccaaacca gcacaattat ctggtggaca
    13261 gaaacagcgt gtcgcaattg ctcgggcatt atcaatgaat ccagatgtat tgctattcga
    13321 cgaacctact tcggcgttag accctgaaat ggttggcgaa gtgcttaata cgatcaaaga
    13381 cttagcacat actggcttga caatgcttat cgtgacgcat gagatggaat ttgcaaaaga
    13441 tgtatctgac cgtgtcattt ttatggataa aggtgtgatt gcagaagaag gtacaccaga
    13501 agatatcttt gtccatccga aagaagaacg tacaaaagaa ttcctttcac gtattttaaa
    13561 tgcttaggat caatagctga ttgggacaaa gagctgcggt gtttaccgca gttctttttt
    13621 atgaattact cataaaaggt aaatttctga aaattttgga atcttagttg tgtttttcag
    13681 aaaactctct taatatggaa gtaattaaac ttttttagtt aggatgattt aaaaatgaat
    13741 gaagagcaag aactgcagcg tggactgaaa aatagacatg tccaactgat ttctattggc
    13801 ggagcgattg gaacggggtt gtttttaggt tccggaaagt ctatccagct agctggccct
    13861 tcgatattgc tcgcctatct tattactgga tgcatctgtt ttttcattat gcgtgcgtta
    13921 ggcgaacttc tgttatcaaa caccaataac cattcttttc tggattttgt tgcagaatat
    13981 cttggcaaaa aagcggcttt catcactggc tggacgtatt ggttctgctg ggtatcgatt
    14041 gcaatggccg atttaacagc catcggaatg tatgtacgct actgggcgcc tggtgttcct
    14101 cagtggcttc ctgaactgat tgcattaggt cttcttcttt gcttgaatat ggtggctgtc
    14161 tcattgtttg gtgagttaga gttttggttt gcattgatca aagttgtagc gatcattgcc
    14221 tttatcctcg taggagctta tatgatcctc acccactata cgacagatat tggcacagcc
    14281 agtatcacga atctatggtc tcatggcgga ttctttccaa ctggtgcaaa aggatttatc
    14341 ttagctttcc aaatggtaac ctttgctttt gctgggatag aattagttgg attagtcgct
    14401 ggagaaacag aaaatcctga aaaagtgttg ccggaagcta tcaataatat tcctatcagg
    14461 atcatcttat tttacttagg atctcttttt gtcattatgg caatctatcc atggaacagc
    14521 ttgaatccag ataacagtcc atttgtagaa gtattttcgg aaattgggat cacgattgct
    14581 gcttccttga tcaatttagt cgtattaagt gcagcagctt ctgcctgcaa cagtgcaata
    14641 tatagtacag gacgtatgct tcgttcttta gcgcaagaag gcagtgcccc taaaaaattc
    14701 aaaaagttaa caacacatca tgtgccaggg aatgctttga cattttctac tatcgtcatt
    14761 ttcatttctg ttatcttgaa ttacgtgatg cctagtgaag tattcacact agtaagcagt
    14821 attgccacta cttgtttctt gtttatctgg agtatgcttg tctacacgca catgaaatat
    14881 cgtaaaagta tcctcggcaa aaaagctcat tcatttaaaa tgccgttgta cccatttagt
    14941 aattatctgg tatttcttta catggccttt gtgtgtgtcg tcttgttcct aggaaaagat
    15001 acgagaatcg ctttattact aacacctgtg tggttcttgc ttctattact aatctatcat
    15061 atgaaatatg aacgtaagaa gtaagaaagt agttgtgaca gaagtggtca gcttcgagaa
    15121 ataagaagga atttacgaaa attgcttctt aaatttttgt gaaatttcgg cttatttctt
    15181 ggagataaaa gcttctgtcc cagcctcttt tctatttccc cggaaacaac cgctgataat
    15241 aggcatctgc ttttttatag gaaaaaatcc aaataccaga tacaaaaaaa cgtccgaata
    15301 acccgatcaa cggtacaaaa aagacaccgg caatcaagca taagttaatc atcatggaga
    15361 taagacttcg acggtccttt gacaaaactc tcacgacatg ggaatctggt ttatttgctt
    15421 tcatgatttg cctcatcaag ataccaaaag aaaaactcca catcgtgtat actaagacat
    15481 aagccatctc aggccaaaaa gcttcagggt tacgcccgac ccaactagta acagaaggac
    15541 ataaagtcag ccaaaagagc aaaaagatat tcgaccagac cactcggtaa ttaattcgtt
    15601 ctgccatctg aaatatacga tgatggttca cccagatcac cgcaacaaat ataaagctga
    15661 tggtataagc taataatgta tttcggatga cccataaaga atgaaagcta gatgtattag
    15721 ggatcttgat ctctaataca ataactctca aaacaatggc taccactcca tcagtaaatg
    15781 cttctaatct cgactttgtc acgatgattc ctcctcagat gattcagcgc ttttatttta
    15841 tcacttacgt tattaaataa ccatcgtttt atatagggaa ttttctgaaa attgttgcat
    15901 atttttcgaa attttgttac ttttaaaaaa accgtaaagg agttatgtat gacaaaaaaa
    15961 ttatcattta aagactatct ttttataggc tccatgcttt tcggtctatt ttttggtgct
    16021 ggaaatctta tctttcccgt tcatttgggt caagaagcag gcgctgctac cttttgggcg
    16081 aatctaggtt tcttggttac cggtatcggt cttcccttct taggggtgat tgccattggt
    16141 gtatcgaaaa gctcaggtgt atatgaatta gcaaaacgga taaatcaaac atatgcgatg
    16201 gtttttacca tcttgcttta cttagttatc ggaccgtttt ttgctttacc tcgccttgca
    16261 accacatctt tcgagattgg tttagcacca tttatcgatc ctagcagaca gacgctatat
    16321 ctagcaattt tcagtattgt attttttgtg ctggcttggt ggttttcaag aaaaccgaca
    16381 aagatattag attatgttgg aaagttcctg aatcctgcat ttttggtttt attaggtgct
    16441 ttgcttctcc ttgctttttt gaatccacta ggttctgtaa atcaagcgcc tattcagcca
    16501 aattatcaag agcatgcttt tttcacaggg tttactcaag gatataacac attagatgcg
    16561 cttgctgctt tagcatttgg gatcatcatt gtcacaacaa tccaaaacat gggtgtaaca
    16621 aaacctgctg aaatcgctaa agacacgatc aaatctggtg cgatcagcat tatattgatg
    16681 ggaatcattt atactttgct cgcttattta ggtgctatga gcttaggtag ctttgctcta
    16741 agtgaaaatg gcgggatcac gctggctcag attgctgatc attatttagg tacttatggc
    16801 agtatcttat tagcatttat cgttatatta gcttgcttga agaccggtat tggtttgatt
    16861 acagcttttg cagaaacatt cacagatttg tttccgcaaa gaaattacgc attctttgtt
    16921 gcacttgcta gtatccttcc ttgtttagcg gcaaacgtag gcttgacgaa tatcattcaa
    16981 ttttcgttgc ctgttttgat gttcatctat ccattagcaa tgacactgat tttactagtg
    17041 ttagttggtc ctttgtttaa gcagcgtacg gctgtttatc gaatgactac ttattttaca
    17101 ttgattgctt cgatttttga tgggttgaac gcttgcccag aaactatcaa acaaacacct
    17161 attgttcaaa atcttttata tgttgcggaa agctacttgc cgtttttcaa attggggatg
    17221 gggtggatcg taccagcagt tatcggtttt gttatcggac tgatttggag tttcgctaag
    17281 aaagaagaag tagcagattg ataaaagagg ttgtgaaaga gacgttcagc cttgagcaat
    17341 aaaaagtaat tttgaaaaat ggcttctcac atttttgcat aaatttgact taataccgag
    17401 aaactgactt ttgaacaccg tttattgaga ggtcgtgaaa aagccgctta gtttcaagta
    17461 ttaagaaata ttttgtgaaa atggcttctc acatttttgc ataaatttga cttaataccg
    17521 agaaactggc ttttgaacac cgtttattga gcgtctataa actgacctga gtattagaga
    17581 aacaaaacgg caaagtagct ccatatactt tgccgttttg ttttgaacta ataccgaaga
    17641 gaagctgatc aaacaacatt tcttttataa tatagatttt agacatatat atgatataaa
    17701 aatagttttc gcaaaaaaac ttgggagcgt caataatttt gtgtaaataa attgtcctcc
    17761 tgcaaaataa ttagttactc agtaaacatt gaaactaat
//
LOCUS       DAIGUC010000057        17438 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.057, whole genome shotgun sequence.
ACCESSION   DAIGUC010000057 DAIGUC010000000
VERSION     DAIGUC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.057"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            9..323
                     /locus_tag="NOB46_002196"
     CDS             9..323
                     /locus_tag="NOB46_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059115.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            878..951
                     /locus_tag="NOB46_002197"
     tRNA            878..951
                     /locus_tag="NOB46_002197"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:912..914,aa:Ile,seq:cat)
     gene            complement(1467..1769)
                     /locus_tag="NOB46_002198"
     CDS             complement(1467..1769)
                     /locus_tag="NOB46_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059116.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(1989..2355)
                     /gene="ssrA"
                     /locus_tag="NOB46_002199"
     tmRNA           complement(1989..2355)
                     /gene="ssrA"
                     /locus_tag="NOB46_002199"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2526..3299)
                     /locus_tag="NOB46_002200"
     CDS             complement(2526..3299)
                     /locus_tag="NOB46_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1059117.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMSNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            3443..3793
                     /locus_tag="NOB46_002201"
     CDS             3443..3793
                     /locus_tag="NOB46_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI1059118.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            3774..4490
                     /locus_tag="NOB46_002202"
     CDS             3774..4490
                     /locus_tag="NOB46_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1059119.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            4490..5938
                     /locus_tag="NOB46_002203"
     CDS             4490..5938
                     /locus_tag="NOB46_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1059120.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(6008..6517)
                     /locus_tag="NOB46_002204"
     CDS             complement(6008..6517)
                     /locus_tag="NOB46_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059121.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(6507..7232)
                     /locus_tag="NOB46_002205"
     CDS             complement(6507..7232)
                     /locus_tag="NOB46_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059122.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(7455..9575)
                     /locus_tag="NOB46_002206"
     CDS             complement(7455..9575)
                     /locus_tag="NOB46_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI1059123.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            9805..10983
                     /locus_tag="NOB46_002207"
     CDS             9805..10983
                     /locus_tag="NOB46_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HCI1059124.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            10999..11757
                     /gene="aroD"
                     /locus_tag="NOB46_002208"
     CDS             10999..11757
                     /gene="aroD"
                     /locus_tag="NOB46_002208"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCI1059125.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            11780..12265
                     /gene="ybaK"
                     /locus_tag="NOB46_002209"
     CDS             11780..12265
                     /gene="ybaK"
                     /locus_tag="NOB46_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCI1059126.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(12336..13589)
                     /locus_tag="NOB46_002210"
     CDS             complement(12336..13589)
                     /locus_tag="NOB46_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1059127.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            13706..15055
                     /gene="gdhA"
                     /locus_tag="NOB46_002211"
     CDS             13706..15055
                     /gene="gdhA"
                     /locus_tag="NOB46_002211"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCI1059128.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            15167..16513
                     /locus_tag="NOB46_002212"
     CDS             15167..16513
                     /locus_tag="NOB46_002212"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCI1059129.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(16821..17207)
                     /locus_tag="NOB46_002213"
     CDS             complement(16821..17207)
                     /locus_tag="NOB46_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI1059130.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(17256..>17438)
                     /locus_tag="NOB46_002214"
     CDS             complement(17256..>17438)
                     /locus_tag="NOB46_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI1059131.1"
                     /translation="QRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLS
                     RAQRRFEGTLRYSLGY"
BASE COUNT         5703 a         3077 c         3425 g         5233 t
ORIGIN      
        1 gatagctttt ggatttttac agtaatttta tcttaataat agcaatatta ttacttctaa
       61 atatttggtt ttttgataag agtagaaatg cagggatagg ttttagaacc aaacgaagta
      121 cgtcttctga aaaaaagtgg gtatattcac agactatttt ttacggaggg gttatttcaa
      181 tcagtttact ttcttcaaca ctttattctt ttaatgttat agacgtttcc atgtcaaatt
      241 ttatatctat tattggaatc cttatttctg caattattac acaactactt cttgtgtttg
      301 aagagaagtc aaaaaataat taaagcaatt atgcctttta gtacaggaat tattacttct
      361 tacaaatgta tagcgaatgt gaagcctgct gttttaattg ttctagaaaa acttttgagt
      421 gaacaattat tttatgttag gatgaattaa tttctctaga gtttataatt aaaaaactta
      481 tttgaaggaa catgcttaaa ccataattgt gtttttcctt ccatcagcat aaaagttcac
      541 ctcaaaaaga gtgtacgaac aaaagttctt tttgtaaacc ttaaaataga ttttcctgaa
      601 tacgtattgg ggatttctaa atgtttgaat gtttttttga atgcaaaatc aatgcaaaaa
      661 attttgtatt tctctacttt tctctccttg accaaaataa aaaaacgttg atttaacaac
      721 gtttttcata catgtttatc tgtctcaacc atacatatat ggagacgcat atcttcacta
      781 tcactcataa atagtcacac tccaagatat gcgataacag gtttgttgcc acgcattcta
      841 ctggttgatt gtttatggct ttatgtggca acaaccacta cccttagctc agttggtcag
      901 agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacagggtac attaatgtag
      961 ccaattgaat cgttctgtgt tagaattttt tgaagagtat tatacaagct aaagcttttc
     1021 ttcattgcca ctcaaatgag tggctttttt atgtatcctt ttatggatta atgaaaggat
     1081 gtttcacata gttatacttc tgtatatttg aaaagtttta ctttgatttt taaatggaaa
     1141 gacatttggg ttatattgtg agataataat aaagaagagt ttaaagcgtt ccccaaaaac
     1201 cacttcccca taagtgtgtt acgctttaaa ctcttttata tttgaagcca ttaaaaagca
     1261 taccatataa ctgtaaaaaa taatgggaaa aagacttata attggagtgg tagttaatta
     1321 gtgacttatt tttgatttta tagcactgat actataaaat atagatatca tcatattaca
     1381 caatcttaat actaacttaa aaaatatccc ttttataagt atggtgataa aatccgttcc
     1441 gggctacctt ttttaggtag cctactttaa tctttatacc tttctggatc aacgaaagta
     1501 tacttcaaat agtcataacg ccgatgatcg ctccgtgcgt ctggcacatc agtcacgata
     1561 tcaaacaaaa aatacacatc tttcttcatt ctggtttttg ttgccggaat tttaaagtag
     1621 ttcttattag agtaatagag attgattaat aagctatctt cgattgctaa aaagaaaact
     1681 tctgaatccc acaccttata aaaatctttg acaaatctat tcgaaggatc aaatttaaac
     1741 cataattgtg tttttccttc catcaacata atgttcacct caaaaagagt atacgaacta
     1801 atgttctttt tgtaaagtag gaatatcatt gataatatgg atggaacata tatattaaaa
     1861 agtgttcttt ttgaatgcta ttttgaatgc cattttcatt catttaacga aaatctgcga
     1921 aaataaaaaa tgctcaaacc cttataaaat aaggatttaa gcatctagcg aaatctgctg
     1981 aaatctcaca atggagacgg cgggagtcga acccgcgtcc aaacacatcg ccacttaaaa
     2041 atctacgttc atagtcaact catttaagga ttcactttac agcttgccga gtgacaggca
     2101 ttctgtatcg ctagtctgat gttctctttt tcaacttaca gacggaaagt tgaaacgtat
     2161 cccactaaag ttaggaccct tactcgagca catgggcgat gccgagagga tctacgctaa
     2221 ctgtttttag gcagctaaag cgtaagagtt gttttcgttt ttagcagtta tatttaactg
     2281 taacgttttt acgtagacgt aacctacgaa acgcaattca agctcgactg tgcctgtcga
     2341 atccgtaacg tccccgttag ctaacaaggg ttacgtgtat ttttcataca aaattagtat
     2401 agcatatatt gggataaatt caataaaaaa gcgaatcata tcccattatt tatataataa
     2461 ctgccccttt cttaagaaaa aataagcgat tttcttaaga aaagaggtag cttcaaaaaa
     2521 agatcttaaa tcagatcaaa atacttcaat gcgtggacaa ttccgccttc tgtatttttc
     2581 tttgtgataa aggtagaaag ttcttttaat ccgtcatagg cgttgctcat agcgattttg
     2641 ttgtcgcaag cttccaacaa ggcaaaatca ttcggaccat cgccaaatcc aaaagtagga
     2701 actttttcca gctgaagttc tttttgcaga cgtttgacac ctgccccttt tgagattcct
     2761 ttcttcactg tatcgatcga gtaaggacca ttccgataaa aagttagctc aggaaaatgt
     2821 tcgtgatagt attcgtcacc tgattgagat aagatcagca acatatttac tgtgttttct
     2881 ttaaagccta aaggatcaat ttccggaaca tctgaatgaa tgaagtcgta agcattgatc
     2941 attgtttggc tatgaccggt acaccagatt ttctgatcgt tatagtaaga aagttcatga
     3001 ccgttcaact gtacatgatc atacattttt tgacattctt ctgaagaaaa tgtttgagaa
     3061 tagatttctt cgccgtctac tcgaatgaaa gaaccattca tggtgaccgc agaagtaatg
     3121 cccgcatctt ccatgataga gtggatttct gcttctgtac gtcctgtagc gatgacgggg
     3181 agaacattgt tttcttttaa tgcgttcata gcttttgcca cttcgggtgt gatttttgat
     3241 ttcgcatcta gtaatgttcc atcaagatca aagaaagtga ttgcacgata atttgacaca
     3301 aataaaactc cttttttatt ggaataagtt tatcttaaca aagaatgaac aaaagacaaa
     3361 cctttcgtga agaattcctg aacatattgg ttcagtcaac aatttagagt atactataag
     3421 aagagaattt aggagggaaa gaatgatttt tttcagtatt ggtatcttat tcttaataat
     3481 tggcagtctt tttcggattc tgccctcaaa aggaaatctg cctttttatg ggtatcattc
     3541 gcctcttgcc gcaaaaacag acgctcattg gcggctggct caaaagacaa gcggaaactg
     3601 gttttttctt atgggcttac tgatggcatt gatcggctat tatttaaaga catctgggca
     3661 tacgaattat tttctgattg aaatgcttct gctagtattt ccaattatgc ctatttttat
     3721 tatgacagaa aagaaattac agaaatatga cctggaaact ggagggaacg ataatgaata
     3781 ttttaatgat tgaagataat caatctgttt ctgaaatgat gcagatgttt ttcttaaatg
     3841 aaggttggga agcaactttc aagtatgatg gaaaagaagg gctcgatgcc tttttagaaa
     3901 acccacaaca ttgggatatg attacactag acctgaattt gcccacactg gacggtatgc
     3961 tagtaggaag agagatccgc aaagtttcaa gtactgtgcc gattatcatg ctgacagcta
     4021 gagattctga aagcgatcag gtgatcggct tagagatggg ggcagatgat tatgtcacaa
     4081 aacctttcag tcctctgacg cttattgctc gaatgaaagc tttgcatcgc cgtagtgagt
     4141 tggcagaagc aagagaagaa gcagtagttt cagatgatca ttttgatatc gagactagtc
     4201 atttcaagat gaatacgaaa acacgagaag cgtatctgga caaccggcca attgaaggac
     4261 tgacgcctaa agagttcgat ctattgttta ctttagcaaa aaaaccacgt caagtattct
     4321 ctcgggagca gttgcttgaa ttagtctggg attatcagta ctttggtgat gaacggacag
     4381 tggacgccca tatcaagaaa ttacgacaaa aaatcgaaaa ggtcggacca caagtcatcc
     4441 aaactgtttg gggagtcggc tacaaattcg atgattctgg tgttgcctaa tgcgttattt
     4501 gtatcagcaa ctcttagctt tctgcggaat ggtcgcgttg atcttattga tcgttggagt
     4561 ttcttttaca caactgacaa aacaaacgat tgaagaaaac aattaccagc aactgtttgg
     4621 atatgctgaa tcagttgaaa agacaacgca aacctatgcc gatacgctcc cgcagtttag
     4681 tcaagatcag gcgtttcaaa atgcattgct gctgacagag caagtactga cagaacaaaa
     4741 tgtgaacttt atatttatcg ataaaaacga acgtgtcatt tatccgacta atacagcttt
     4801 actgaatttt accttaacag ctgatcaatg gaaaaatctg aggaatggac gtcaagaaaa
     4861 attcacatcg aataaaaata ttttaggaca agcacaggcg acctcttacg cacttgtgcc
     4921 atttaatttg aatcatgaat tctatggagc acttgtagtt agtcaacctg cgcgaaatat
     4981 cgataacagc gttcgtccaa ttacactgaa cctgttcaaa ggatttattt tttccagtat
     5041 cgttgcagtt attgccagct atgcttttgc agcattccaa gttaagcgta tcaatcggtt
     5101 aaggaatgcg acgaaagaag tgacgaatgg taattttgat gtacagctcc ccgtacatga
     5161 caaagatgaa tttgatgagt tagcagatga tttcaataaa atgacgaatt cattgaaaga
     5221 atctcaagca gaaattgaag aacaagaaaa tcgtcgaaga caatttatgg cagatgcttc
     5281 tcacgagatg agaacacctc ttacgacaat caacggactt ctggaagggt tagaatacaa
     5341 tgcaatccct gaaaatcagc gagaaaacgc gattaaattg atgaaaaatg aaacagagcg
     5401 tctgatccgt ttggtgaatg aaaacttgga ttatgaaaaa atccgtacga atcaaatcag
     5461 tatggtcatt aaaaaattca atggaacaga aacattgaaa aatattgttg cacagttaga
     5521 agctaaagca gaagcagcag gagatacatt gacattgaaa gccgttgatg atattgatgt
     5581 ttacgctgat tatgaccgat ttgtccaaat catggtcaat attattcaaa acgcgataca
     5641 gtttactgaa aacggccaaa tcacgattac tttagaaaaa ggctatcttg aaacgatcat
     5701 cacgattgaa gatacgggaa ttggaatgtc tgaacaacaa atgaaaagta tctgggatcg
     5761 ttattataaa gtagatcctt caagaaaaaa tacaaaatat ggtgaatcag gattaggttt
     5821 accaatcgtg cagcaacttg tacgcttgca taaaggaaaa ttagaagtag aaagcgaact
     5881 aggaaaagga acaaaattcg ctgttcgttt gcctgacgta gaaatcaaaa aagagtaaaa
     5941 aacaagcggt ataaaagatc atgaatcgat cttctatacc gcttgttttt actataaaat
     6001 gattgattta gcccgcgggc tctaaacgat caatataagg actttgagca atagtagcat
     6061 catgagtaaa gagtaagata ccttgatttt cttcatgagc taaataagaa agcaagtgga
     6121 gtagctcttg gatctccaat acactaagtt catcaaatgt atcttcaata acaatattgt
     6181 ttcgcttgga aagcaaggca tgaagtaatt gcagctttac tttttcaaaa gacgtcaact
     6241 cagctgccgc acaattaagc aaggaaggag agatatcaag tttttcttga taggccaaac
     6301 gatcttgttt gatttctttt tccggtacat ccaacaggac atggtcttta agattcagat
     6361 aaggaaacat cggccaattt ttttggatga tcgcaaaatt atccagtttt gcaacaagaa
     6421 cctctttttt caagtgctcc aatattttat gctgtttttc gagaggacac aaaataacgg
     6481 tcaagtgttc agcatgaatc aaatattcag gtttcattac gtccaggcct cctactttgc
     6541 aaatgatgga taaaaaaagt gaaagggaat agactaagaa tgagacagca tccactgagc
     6601 ccaataagag tttgggcaaa tcccttaagt atatctgtga aaaaaagatc attttggaaa
     6661 tcgatggtaa aaaaagtctg ttgatccatc ggaattgtaa gtccgcttac cgaagtcaag
     6721 atatcacgga tatctggcag ttcagtagtc tttaagacaa gaaaattgat cctttgaaga
     6781 agcgcttcat aaactgactg gaagcttacg atccacaata aaaccaagat acaacaaaga
     6841 aagagaggaa agaacagctg ccagaaaata aaaaggaata atttggtttt agaaagacca
     6901 gtcaggtgcc aattgatcaa ttcctgcttg ttttgcctga ctgaatagta aaagaaaaag
     6961 ataaaaagga aggcaaatag aaaaaataaa ctgaatatgc cttttatata aaatcggcta
     7021 gctaattcta aagccggaag aagctctgta gatgcagaag cgccaataaa tgaaagccga
     7081 tcttggactt gattggctaa agccgattgc aaatggtaaa gagtcaggca tgctatcaat
     7141 aaaaaagcag aaaagcttga aaataaacaa tagagtattg tctgcttttt gtaataaatt
     7201 aatcgagcag tagcatagcg gattattttc atacttttca cctctataaa aagtatagaa
     7261 aatgaatatg aataaagtat gaaattcctt tagtgaaatc acgaattaaa accagaaaat
     7321 attttgtaaa aagcaagagg ttgtgaagaa gctgccctat tctattaccg tagatgcaag
     7381 cttttgaaca ctgtttattc gaaaagagga gcagcgacaa taattttgtc gctgctcctt
     7441 ttaaatttat tttatcattc ggaagaactt gtggtcgttc cgtgaagttc ttggtacgtt
     7501 tgcgttttat aaagatcaac agttgattgt ccgttgtgtt cactaaagac actagttgac
     7561 ttgtcaccaa gagatttttc agcttctttt aatttctcta agccattctt gtagtcataa
     7621 tcactggtat caattgggtc taatccacta ttcgtataga accgaagaag atcaccatta
     7681 ttgatttggt cagaaacagc taactgttta tcaacttttt ctttcagtga atcaatttca
     7741 ttctgtactt cctcagtagg ttcagtaata gcttcaccag tttcgttact atagatcgta
     7801 ccaccgtagt aagtatattt tggtgtaaca aaatcaccat cacggaaaga aacaagctgt
     7861 tcatgatctt tcgagaatag atcttgtcct aactgaatat aattttttgt atctacacct
     7921 agtaagtgaa gtaatgtagg caaggcatca acttgtccgc cgtaagtgtg attgattccg
     7981 ccctgtgttt gtccagggat atggatcata taagggacac gctgcatttg tgcattgtcg
     8041 tagtttgtcc aagtagaact tgtttttcca actaattcag ctagattttt atttcttgaa
     8101 ttcgagacac cgtaatggtc accgtaaagg acgatgactg aattatcata caagccgctt
     8161 tctttcaaat aattgaagaa ttcttgtacg gcggtatcta aataattggc tgtcgcaaag
     8221 taaccgttga tcgtttcatc atttgtattg gctaacggga atcctgcttc gtcattggtg
     8281 aattttgaat aaggataatg gttagataca gcaatgaatt ttgaataaaa tggttgttgc
     8341 agacgttcca agtattgtac ggattgttgg aaaaatggtt tatcatgcaa cccgtattgg
     8401 aacgaattgt catcattaac atcataataa gaagaatcaa agaaataatc atatcctaaa
     8461 ttcttgtatg tctcgtttcg attccagaat gtaccagcgt tcccatggaa taccgcacta
     8521 atgtaacctt gtgtttgact taaaatatca ggtgcagctt ggaaagtatt ttttccgcct
     8581 aattgtgtga acaaggagcc ttgattcaag ccaaacaatg aattttccat cagcgtttcc
     8641 gcatcgcttg tttttcctgc ttttacttga tggaaaaagt tgtcaaaact gaacgtgctg
     8701 ttgctgtggt aaagactatt gatgaaaggt gtaacttcat gctggagacc attctcatct
     8761 gtcaatttat aatcgatcag gaattgctgg aagctttcta aatggatata aatcacattt
     8821 tttcctctag cgagcccgaa caaatcgtca tttggtgctg cataatgttc ttttacataa
     8881 ttttctactt ctttcatatc attgggactt gcttctgccc gcacttggtt tgtctggtaa
     8941 gtttgaacac cgtcataaac catgaaagca ttcaagccaa gatatttgac caaataatca
     9001 cgagagaatg ttcgagtcag caattctgga cgatcagctt ccgccataaa aagatttcct
     9061 gagaaaatca taactgctaa tgtagagatc gcaaaagcca ttcttgctcg gatcgggcga
     9121 gggtccaact tgattttttt tgcaatcagc agaacagtca agataataaa atcgatccaa
     9181 tagatcacat catatgggcg aaacagtcga atggcacttt ctcccagacc actcgctact
     9241 ttcccagcac ctaaaatcgt gttgatcgta atgaagtccg tgaattctcg ataataagtg
     9301 acattcgaaa aaacaagcaa tgtcaaaaga aaataaatga ccatcatcgt gatataagca
     9361 actctagggc gtctgatata aagagcaatt ccaagtaata acaatgtagt tgcaataggg
     9421 ttgataaaca agataaagta ttgaatgcca ctttcgattc cgagatggaa atcaactaaa
     9481 taggcaaaaa tcgttttcaa ccaaagtaaa acgactagta aagaaaaaaa tccgagcctc
     9541 ttattcaaaa aggcaggtgt ttttatacat ttcaagataa tcttcctttc tgcacttctt
     9601 aatcacagaa gtgtcctgaa accatgttac acagctcact tattctcatt tattttacta
     9661 gtatgacaat atagtgtcaa ttgaaaccag aagtttatgc tgtttcatta aggttttctt
     9721 taagcttcat gaaaaaatga gcagtaagac aagtcctatg ttttttgtta tacttgggaa
     9781 gagaaagcta aagcaggtga aggaatgaaa gtaaaagtaa aaaaaagagc aagcaatcga
     9841 ttgaaaaaag gatatccact gatccaaaaa gaagaccttg ctcatcccca aaaagaaacc
     9901 acgcaatggg tggaattagt tgattcgcaa aaccaattta tcgcaaaagg atatctagga
     9961 aagcagaata agggaatcgg ttgggtattg agccagcaga acatcccatt tgatcaatct
    10021 ttttttgaag aattttttgt gaagtcaaaa gaaaaaagaa ctttcttttt ttcagatgat
    10081 tctactaccg cttttcgtat attcaatgga gaaggagacg ggatcggcgg tctgattgtt
    10141 gattattatg caggttatgc tgttttttct tggtataacg aaacgttata tgcacatcgt
    10201 gaattattga ttcaagcttt tcgtgaaatc tacccggaaa tcataggagg ctatgagaaa
    10261 attcgatttg aatcagtaaa tctgcctgag agccagttca tttacggaaa agaggcaccg
    10321 gaacccttga tcgtaaaaga aaacggagta aaatttgccg tttatttaaa tgaaggatta
    10381 atgactggga tctttttaga ccaaaaagaa gtacggggat cattagcaga aggtttcgct
    10441 tctgggaaaa cagttttgaa catgtttagt tataccggcg ccttttctgt tgctgccgca
    10501 atgggagggg caatcgaaac aacaagtgtc gatctagcaa aacgcagttt aaaaaaaaca
    10561 caggaacagt ttgaagtgaa tggtttggat gtcgatcagc aaaaaatcat tgttatggac
    10621 gtattcgagt atttcaaata cgccaaaaga aaacaatttt tatatgacat gattgtattg
    10681 gatccaccaa gttttgccag aaataagaaa aaagtctttc gcgtagcaaa agattatggg
    10741 gaactggtca aggatagtct ggatatttta gcagaagacg ggatacttat tgcgtctaca
    10801 aatgctgcga atgtctcgat agaacaattc caaacaatga ttgaagagga attccatgcc
    10861 aaaaatgttt cttttgaaca acttgcttta tatcgtctgc caaaagattt ccagacgacg
    10921 gatacctttt tagaaggcaa ttatctgaaa gtgtttgttt atcaaattaa aaataaccat
    10981 tagaaggagc gatgcagaat ggttcgggta aagggattga atataggaag cggtagacca
    11041 aagatttgtg cgcctcttat cggggccgtc cgagaggaag tattacgtga agcagttctt
    11101 gcacgtgaag caggggccga tttagtcgaa tggcgagtcg atcattatcg tgaagttttt
    11161 tcttttgatg aagtagcaga aacattggtt cttatccatg agatgcttga tggactgccg
    11221 ttattattta cgtttcgtac cttagctgaa ggcggagaac aagacatatc gatccgtcag
    11281 tatcgcgacc tttatgaaca tgtgatacac acaggattag tagatatggt cgatatcgag
    11341 ttgttcaaag tagaaagtct aggaaaaaga ctgatagagg aaatcaagtc tttaaacatt
    11401 cctttaatta tcagtagtca tgattttaaa gaaacaccag cagaccctgt cttgctttac
    11461 cgattgaatg ttatggaaca ttttggagcc gatatcggaa aactggcagt aactcccaat
    11521 aatgaacgag atgttttgcg gttgatggag ttgactagac gggcaaatgc ttttgtctcc
    11581 atgcctatta ttacgatgtc catgggaaat cttggtaaaa tttctcgtct ggttggcgga
    11641 acgacgggtt ccgttatgac atttggttcc ttaagcagcg attctacttc tgctccagga
    11701 caattaccgg tcaaagcatt gaagcaaatt attcaattat taaatgaacc gttgtagaac
    11761 aagtttgagg tgatattttt tggcaaagaa aaaaatagta aaaacgaatg caatccgtat
    11821 ggtcgaacaa aaaaagattc cctatacaga gcacgaatat gagtgggacg aaagccacct
    11881 aagtgcgtca tcggtcgctg aacagcttcc agaaagccaa tctcgtatat ttaaaacact
    11941 ggttgctgtg ggcaatgtga cggggcctct tgttgctgtg ataccgggag aagccgaatt
    12001 gaatctaaaa aaattagcaa aagtttcagg gaataaaaaa gtagaaatgc tccatttaaa
    12061 agatttggaa gcaacgaccg gatacatacg tggtggctgc tcgcctatag gtatgaaaaa
    12121 actatttcct acttatttag atcaaattgc agaaagctat gaacaaatca ttgtctcggc
    12181 tggcagaaga gggctacaga tggagttagc acctcaagat atctgtgcat taacgagcgg
    12241 acaatttgca gatataaaac aataaatcat acgtataaaa gaaagaagga ggccgggatg
    12301 ttgtttgtcc agtctccttc tttctttttt atacattatg ctctttgccc ggcattcatt
    12361 cctgctacat gccctgtagc gaaagccgct gtgatattaa agccgccagt ataaccattg
    12421 acatccagta attctcccgc aaaatacaga ccatcaatga ttttactctc caatgtttta
    12481 ggataaattt cctttagaga aacccctccg ccagttacaa atgatttctc aataggaaaa
    12541 gttttgttga ttgatagctt aaactctttg catagttgaa caaaatcttg aatttgtttt
    12601 tgagaggctt gttgtcctgt cagatgatcc atttcaagcc gctcaagaaa gaaaactaac
    12661 aatcgctcag gcaatatacc atgccaagca ttgaccaagt tctttttggt tgctttactt
    12721 ttttctgtca atatatgaat aagctcttgt ttggtttgtg tagggaaaca atccagagaa
    12781 agtgtcactg gttctcccgt tttctctaat tctttattga caaaacttga acaacgcagt
    12841 gcagccggac cagaaatacc gaaatgggtg aaaagtaaat ccatcgtatg ttcagtcaat
    12901 acacgacctt ttttatttaa aacgcgtaaa gtgatgtctt gtaaagaaag cccttgaagt
    12961 gttttctcct gaatatacgg ttcatccgat atcaaggggg actctgtcgc ataaagaggc
    13021 gtcaccgtgt gacccactcg cttcacgatc ttgtacccat ctccagtaga accagtagat
    13081 ggataagtcc gtccaccagt tgttaagata atggcaggag catggaactc ttcgaattcc
    13141 gtgcgtatac cgtaaatttt atgttctttg tggatcaatt tctctactcg agtagagaat
    13201 agaagcgtca catctagttc tttcagacga ttgagcaatg cttcgataat cgtttttgat
    13261 ttatttgtta caggaaacat ccgtccatga tcctcttctt ttaaatgtac gccttgtgat
    13321 tcaaagaagt tcatgatatc gaaattattc cattgcgcaa acgtactata taaaaacttt
    13381 ccatttccag gaatatgtgc aatcaaatca tcaacaggac gattgttcgt aacattgcac
    13441 cgaccaccac ctgtcatcag tagttttttt cctgcttttt tgtttttttc gatcaagagt
    13501 acgcgtgcgc cttgttcagc tgcactgatc gctgccatca tcccgcttgt tccagcgccg
    13561 actacgatca catcatacag tttttccatt ccctcacctc aaggaaagtg tagcatatct
    13621 gaagaaagaa aacagaaaaa aatgttttga gccaaaagag aaaatgagct aaaatgaggg
    13681 aagataagca aaggagcgtg gaacgatgac aaacgcaaca gaatatgttc aagcaattca
    13741 agaaaagcta catcaaaagg atcaagggca agaagaattt ttacaagcaa tcgatgaatt
    13801 catgcccacg gttatgtctt ttttggacac tcatcccgaa tatatcgaaa agaatatctt
    13861 agaactttta acggaaccag aaagagttat tcaatttcga gtgccttggc aagatgatga
    13921 aggaaactgg cgagtaaata gagggtaccg tatccaatac aactcagcta tcggccctta
    13981 taaaggtgga ttgcgcttcc atcctagtgt caatctaagt atcttgaaat ttttggcttt
    14041 tgaacagatt ttcaagaata gtttaaccgg tctgccaatc ggtggaggaa aaggcggaag
    14101 tgacttcgat cctaaaggaa aatctgataa tgagatcatg cgtttttgtc aaagtttcat
    14161 gctggaattg tcaaaacata tcggcccatc gattgatgtt cctgcgggag atatcggtgt
    14221 aggagctaga gaaatcggct atttgttcgg cgaatataaa cgattgaaaa aatatgatac
    14281 tggtgtgttg acaggtaaac ctttggattt ttggggaagt aagatacgta cggaagctac
    14341 tggttatgga ttagtgtatt atgtcaaaca tctattgaac gaagaaaaag attcatttaa
    14401 tcaaaaaaca gtttttgttt ccggaagcgg gaatgtagcc atttatgcaa tcgaaaaagt
    14461 gcaagagcta ggcgggaaag ttgttacatg ttcagattct agcgggtaca tctatgatcc
    14521 agaaggaata gatgtgaaac tattgaaaga agtcaaagaa atcaatagac aacgtttgac
    14581 ggaatacgca aaccaacgtc cttctgctat ttatcatgct ggagaatctg tttggacatt
    14641 gaaagaaaaa gcggatatcg ctttgccatg tgctactcaa aatgaaatag acgaaagctt
    14701 ggccgaaatc ttagtagaaa atgggatcaa aatcgtagca gaaggcgcta atatgccatg
    14761 tacagtaaaa gctgtttctg ttcttcatga agcaggcgtg tggtattgtc caggaaaagc
    14821 tgctaatgct ggaggagtag cagtatctgc tttagaaatg agtcagaacg tccagcgatt
    14881 gacttgggaa agagagcaag tggatgagca gctggatcaa atcatggaaa cgatttacca
    14941 tacgtgtcgc caaacagcag ccgagtacgg cgacgaaaaa aatctgcttc ttggagcaaa
    15001 tgttgctgga tttgaaaaag ttgccaaagc aatggcagca gaaggtttag tttgaaaaat
    15061 gaaactttct tggaaatatt gtcagcattt tgtttatttg cttgaaaaat aataaaaaaa
    15121 aacgtaaagt attacctgta gagtaaacct ataaggagga gaacaaatgg cacacattca
    15181 ttttgactat tcaaaagtag caccgtttgt caacgaacaa gagttagggt acatgcaaag
    15241 ccaagtaaca gcagcccaca acgaattacg ggaaggtact ggcgcaggaa gcgacttccg
    15301 cggctggatc gatttaccaa cgaactatga caaagaagaa tttgcacgta tcaaagaagc
    15361 agctaaaaaa atccaatctg attctgaagt attagttgtt atcggtatcg gtggttctta
    15421 tttaggcgct cgtgcagcga tcgacttctt gaatcacaca ttcttcaatt tattagatag
    15481 caacacaaga aaagcaccac aaatcttctt tgccggaaat tcaatcagct caacatatat
    15541 tgctgacttg atcgaagtaa tcggtgatcg cgacttttca gtaaacgtta tttcaaaatc
    15601 tggaacaact actgaaccag cgattgcgtt ccgtgtattc aaagagcttc ttgttaagaa
    15661 atatggacaa gaagaagcaa acaaacgtat ctacgctaca acagataaag caaaaggtgc
    15721 agttaaagta gaagcagatg cagaaggttg ggaaactttc gtgattcctg atgacatcgg
    15781 cggacgtttc tctgtattaa ctgctgttgg tttgttacca atcgctgtta gtggtgcaga
    15841 tatcgatgca ttgatgcaag gtgccgctga tgcaagcaaa gcatactcaa gcgacaaact
    15901 agaagaaaac gaagcttacc aatacgcagc aatgcgcaac attctttacc gtaaaggcaa
    15961 agtaactgag ttgttgatca actatgaacc aggaatgcaa tacttctcag aatggtggaa
    16021 acaattgtat ggtgaatctg aaggaaaaga ccaaaaaggc atctatcctt caagcgcaaa
    16081 cttctcaact gatttgcact ctttaggaca attcatccaa gaaggacgtc gcaatatttt
    16141 tgaaacagtt gtgaaggttg aaaaacctcg taaatcaatc acaattcctg aacaagcaga
    16201 agatttagac ggtctaggct acttgcaagg aaaagaagtg gacttcgtaa atacaaaagc
    16261 atttgaagga acattgcttg ctcatacaga cggtgacgtg cctaacttgc tagtcaaaat
    16321 tccagaaatg gatgcttata cattgggtta tacaatgtac ttctttgaaa ttgctgtagg
    16381 tatttcaggt tacttgaatg gaatcaaccc attcgaccaa ccaggtgtag aagcttacaa
    16441 gaaaaacatg ttcgcacttc taggcaaacc aggctttgaa gatcttgcta aagaattgaa
    16501 cgaacgcctg taagataagg gtttttcgct agatttaaat aatcagtgat agaaacatgt
    16561 tcgctttaaa atgaaaactg gtacccattt aggtactcaa acatactgca tcgtttattc
    16621 agaataaggg gctgtgacaa gacgtttgtc acagtccctt gtttgtatag aaatcgattg
    16681 attgccttgc tctttagttt gttttaggac tttaagaaca gtgaggctga cttcgaaggt
    16741 taattctgtt tttttgtttt ctagaatcag taagcaaaaa agcactcact tcgagtgctt
    16801 ttttgcgata tattcttagc ttaagatagg cctaattttt cttttacaga tgagggtacc
    16861 ttatcgctgg taattacttt tttctctatg atccgctttt cgcttgcttt caactgcaag
    16921 atcgttcctt cggggtaagc agaaccattg gcagagtcac cagaagtaat gacatcgaaa
    16981 tctaactgtc ttttttcacc gttttcagca taagcatcta cgttgtattt aaaacctctt
    17041 ccaattactt ccccattatc tgctttgata tcagtttctg caggcattgg agctttgact
    17101 accgcataat aatctttacc tacataagta gactgatagt agtcccaacc tttccatcct
    17161 ataaaagcaa tcaatatgat aacgatcaac cctaaaattt ttttcatgaa agatctcctt
    17221 ttttattttt attatacccg tggtgctagt taattttaat atcctaaaga atatctcaaa
    17281 gttccttcaa aacgtcgttg tgctcgactt aatagaacac tgtaagccag taatatgctt
    17341 tcaaatctac tctctagccc tttaacagaa cgtgagttga aattttgaca acctaatttt
    17401 tctaaggaag aaaaaacagt ctcaactgtt tttctttg
//
LOCUS       DAIGUC010000058        17007 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.058, whole genome shotgun sequence.
ACCESSION   DAIGUC010000058 DAIGUC010000000
VERSION     DAIGUC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.058"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..126)
                     /locus_tag="NOB46_002215"
     CDS             complement(<1..126)
                     /locus_tag="NOB46_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HCI1059132.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="NOB46_002216"
     CDS             complement(230..541)
                     /locus_tag="NOB46_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI1059133.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="NOB46_002217"
     CDS             complement(543..740)
                     /locus_tag="NOB46_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HCI1059134.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="NOB46_002218"
     CDS             complement(1134..2861)
                     /locus_tag="NOB46_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HCI1059135.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="NOB46_002219"
     CDS             complement(2854..4047)
                     /locus_tag="NOB46_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI1059136.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="NOB46_002220"
     CDS             complement(4234..4878)
                     /locus_tag="NOB46_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1059137.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="NOB46_002221"
     CDS             complement(4972..5106)
                     /locus_tag="NOB46_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCI1059138.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="NOB46_002222"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="NOB46_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCI1059139.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="NOB46_002223"
     CDS             complement(7237..7710)
                     /locus_tag="NOB46_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCI1059140.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="NOB46_002224"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="NOB46_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCI1059141.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="NOB46_002225"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="NOB46_002225"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCI1059142.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="NOB46_002226"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="NOB46_002226"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCI1059143.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="NOB46_002227"
     CDS             complement(11757..12896)
                     /locus_tag="NOB46_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI1059144.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="NOB46_002228"
     CDS             complement(13205..13918)
                     /locus_tag="NOB46_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCI1059145.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="NOB46_002229"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="NOB46_002229"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCI1059146.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="NOB46_002230"
     CDS             15107..16639
                     /locus_tag="NOB46_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI1059147.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="NOB46_002231"
     CDS             complement(16830..>17007)
                     /locus_tag="NOB46_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1059148.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DAIGUC010000059        16855 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.059, whole genome shotgun sequence.
ACCESSION   DAIGUC010000059 DAIGUC010000000
VERSION     DAIGUC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.059"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..832)
                     /locus_tag="NOB46_002232"
     CDS             complement(<1..832)
                     /locus_tag="NOB46_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059149.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(846..1643)
                     /locus_tag="NOB46_002233"
     CDS             complement(846..1643)
                     /locus_tag="NOB46_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1059150.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(1676..1960)
                     /locus_tag="NOB46_002234"
     CDS             complement(1676..1960)
                     /locus_tag="NOB46_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCI1059151.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(1957..2958)
                     /locus_tag="NOB46_002235"
     CDS             complement(1957..2958)
                     /locus_tag="NOB46_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCI1059152.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(2960..4027)
                     /gene="gnd"
                     /locus_tag="NOB46_002236"
     CDS             complement(2960..4027)
                     /gene="gnd"
                     /locus_tag="NOB46_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HCI1059153.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            4026..4874
                     /locus_tag="NOB46_002237"
     CDS             4026..4874
                     /locus_tag="NOB46_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1059154.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            5520..5726
                     /locus_tag="NOB46_002238"
     CDS             5520..5726
                     /locus_tag="NOB46_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HCI1059155.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(5928..6929)
                     /locus_tag="NOB46_002239"
     CDS             complement(5928..6929)
                     /locus_tag="NOB46_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1059156.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(6934..8846)
                     /locus_tag="NOB46_002240"
                     /pseudo
     CDS             complement(6934..8846)
                     /locus_tag="NOB46_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9014..9520)
                     /locus_tag="NOB46_002241"
     CDS             complement(9014..9520)
                     /locus_tag="NOB46_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1059157.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            9680..10120
                     /locus_tag="NOB46_002242"
     CDS             9680..10120
                     /locus_tag="NOB46_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI1059158.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(10146..11303)
                     /locus_tag="NOB46_002243"
     CDS             complement(10146..11303)
                     /locus_tag="NOB46_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059159.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(11306..11662)
                     /locus_tag="NOB46_002244"
     CDS             complement(11306..11662)
                     /locus_tag="NOB46_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059160.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(11960..12934)
                     /gene="sgrA"
                     /locus_tag="NOB46_002245"
     CDS             complement(11960..12934)
                     /gene="sgrA"
                     /locus_tag="NOB46_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HCI1059161.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(13130..13969)
                     /locus_tag="NOB46_002246"
     CDS             complement(13130..13969)
                     /locus_tag="NOB46_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI1059162.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            14154..15041
                     /locus_tag="NOB46_002247"
     CDS             14154..15041
                     /locus_tag="NOB46_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI1059163.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(15635..16330)
                     /locus_tag="NOB46_002248"
     CDS             complement(15635..16330)
                     /locus_tag="NOB46_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCI1059164.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(16314..16712)
                     /locus_tag="NOB46_002249"
     CDS             complement(16314..16712)
                     /locus_tag="NOB46_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI1059165.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         5038 a         3423 c         2595 g         5799 t
ORIGIN      
        1 aaaatccgtc atcatagtca tcttcgtcat caaaagatgc tgaattgtta ttgcttgtgg
       61 caggctgtac ttgtttccct ttttgcgact ggacaaagat caaagcgata ataatcccaa
      121 aaatggcata agtaaccatc gtaatatcta aagatttcaa aacaacactc ataaaataag
      181 caaggaagaa aaagaccaga taatcttttc gaccgataac gtatacagtt gtcgcgatac
      241 cgattgccgc taaccctcca cctactactt caagaatgtg gataacgact gttccctcta
      301 aagctttgat tacatcagcg atcaatggcg cccctaaata taaagcaatg aaaacaagcg
      361 gaacgaataa taaaaatgag gcaaccgttg gataaagaat aattgatcgg gccatagctt
      421 ttgtattcaa atcttctaca gctttgtctg tatatttacc taaaaaagta ttgatgaaaa
      481 aacgaaactg atacaagtaa cttccgagca atccgactgg caccgcaacg gcaatcgctg
      541 cttctggcga cagatcccct aataatgcga ctggtactgc gatagctgct gcaatagatg
      601 gttcagctgg cattgatcct cctggagaaa aaacccccat ataaatcatt tgcaaagcgg
      661 ctgtaacaat catcgcttgt gcaacttccc ccatgatcaa cccgacgact aatccagtca
      721 tcaaaggaga aaaacgtaag gtcaacgtgg ctcctccacc taaccagcgg gacataaccg
      781 cggctaccca taaagcaatc aacaaacttt gtactacact taatgtttcc atgtgtcctc
      841 ctccttcaga tctttctgat ataaccttcc agttccatca ttgactgtat cagtgatttc
      901 tgtgttacct ctataggaat caaatgcact ttctctttcg aatcaataaa ttcagccatt
      961 ttatctatta tctgtttatc tttcggaaat aatcccattt gttctagaga aaccggcagt
     1021 tctaattccc gatacaaagg atataactcg tctatttttt cccagcgacc ttctagtgcc
     1081 agttgataga aaatcccata cgctactttt tctccatgta gaaaacgatg gctttccgga
     1141 atatatttac tgatagcgtc atgcatagca tgtgctgccg catttcttgc gtatttatct
     1201 cctaatcctc caactaaacc agcaacagca aagataatct ctgaaagctg tttgaactcc
     1261 gatgtcagtt ttctttgtgc catatcttgg attgctttag cagaatgatt caaaatctct
     1321 tctttgcaga tcttcgcagt atcttgtgct agcttcaaaa atgattcatc ttgcaaaaaa
     1381 tcttgttcta agatgagctc agattcatac cattttgcta gtgtatctgc taacccggca
     1441 atgaaatatg gaacagggga atcaatcact aattggggat ctgttataaa aaaagcagct
     1501 tgtctgtaaa agtgttctgt tttcccttct gcttgtccat tctccttata catgacagca
     1561 agaggtgtcc atggagcaca attactagct aaagtaggga tgactccgaa atcgattctt
     1621 gcaagattgg cactataacc cactagatcg gtcagttttc ctccgccaac gccaactacg
     1681 aaatcgattt catttttttg atgattgtag ctattcgtct ggcttcagca taactacatt
     1741 ctccagaata acgatgataa aaaaattgaa tcgtttcgtc attcaaaaat actaatttag
     1801 gtagcgcctt ttcccatgat accgttccgt gggtgaccag tactcttttc gcgccgtatg
     1861 atttcaagag atcagaaact tttgaaatac caccttcttc atataaataa aattgagggc
     1921 ctgttttcac ttttaaaccg ttcaccattt tcttcatcat ccttttatat agttgctctt
     1981 tgtctggaca gaacgttcag gaagaaggtg ctgactgatc tgttcgacat ctctgacaca
     2041 tttttcaccc attgcttcta aacattccct tgtgtaggcc gatatatgtg gcgtaatcac
     2101 tacttgttca aacgctaaat acggatgatc ttgacgtccc ggttcttctt ctaaaacatc
     2161 tgtggcatat cctgcgatct ttccgctttt cagaccatta atcatcgctt cttcatcaac
     2221 tagagcgcct cttgcactat tagatagata aacattttct ttcatctgat cgacttcttt
     2281 atcagaaatc atgtgatagt tctcttctgt caaattcgca cataaacaaa tgatatctga
     2341 ttgttccagt aattcttgaa gttctacttt ttttgcacca aagctttcga tgtataaatc
     2401 tgatttgtaa ggatcataag ctagaacatc acagcgaaaa ccgttacgca aaatttcgat
     2461 tactccgctt ccggtatttc ctgcaccaat cacaccaact gttttgttaa acagcgtcct
     2521 accgacgaac tccgcccgat cttcccatcg atcgtccttg actcttgctt gtgcttgtgt
     2581 cgtgcgtcga agcatggaca acaaattagt tatattattt tctgctacag catttcgttc
     2641 aactaaagca ggtatgatag atacgattgt ctggtgttct tttgctgctt ttaaatcaat
     2701 attgttgtaa ccaataccat gtcgggaaat caatagcagt tcatctttgt tttcaaaaaa
     2761 atctcgtcga aaaaatggcg taacacttgc aataatgata ttgaatcctt taagtaactc
     2821 cgctagttct tttcctggaa tctcttgatc aacagtaaag aaatgaacgt ctccaactga
     2881 ctttaatctt tccaagtggt gtggaaagac tcttccgaaa ctgctggaat taacgattgc
     2941 tatatgataa tctggcattt tactcaccct tttcaactat ttcatgtccg ccaaacccat
     3001 ttcttagtgc tgaaactact tttgctgaaa aactatcttc ttcctgtgaa agattcctca
     3061 tgaacaaact agttgcaatt actggaactg gaacagccat ttctagcgct gtttcaaccg
     3121 tccattttgc ttcacctgat gcagaaacga ttccccgata attacttaaa ttgggatgtt
     3181 cgtttaactg atcttccatg atttccatca gccagccgcg aatcaccgaa ccatgattcc
     3241 aaacacgtgc gacttgttcc aagtcaaaag catactcact tttttgtaca agttggaatc
     3301 cttcaccgat tgcttgcatc attccatatt cgattccatt atggatcatt ttcaagaagt
     3361 gtccgcttcc ggatgcacca gcatacagat atcctctttc aattgctaca tctttgaata
     3421 attgttccac ggatagaaaa gtttctttat ctcctccaat cattaagcag gcttgatgtc
     3481 gtgctccttc gattcctcca gaagtcccac aatccaagta accgatttca tttttctgaa
     3541 actcttctgc tcgacggatt gaatctttat aataagagtt tccgccttca ataataatgt
     3601 ctcctggtcc gagttttgga aaaagttttc ttaacatgtt ttcggttatc tctccagcag
     3661 gaagcattaa ccagatgatt tttttctgct caaaagtagc tagaaattca gagatctctt
     3721 gataagcagg aatgtcattt tctcttgcct gactaacagc tgtacttgaa atgtcgagtc
     3781 cttgtacttt gtgatggtgc tcttttaagt ttaaagctaa attcaatccc atttttccca
     3841 aaccaattac accaatttcc atgatagcgc ctccatttct tataccctca ttatacaaaa
     3901 aaattttttt gtaaatagat tttacaaaaa tattttttgt ttgatttttt cctactctcc
     3961 ttgtatcttt aacattaatg agaacggaaa aaatgataat cttattatga aaatgaggaa
     4021 ttctcatgag cgtctccata agactacaaa tcaaaacaat gtacaacgac ttcagcccaa
     4081 aagaacaggc tatcgccgat tatattttag aaaatccaag caaagtaagt catagtccta
     4141 ttagcaattt agcaagtgaa ctgggcattg ctgactctac tttttttcaa tttacaaaaa
     4201 aacttggtta taatggattt aaagatttta aaatggccat gttgatccaa gaaaatgatc
     4261 tatctgctat ttctatccac gaaaatattc agaaaacaga tactgagctc actatggcgc
     4321 aaaaggtgtt cgagtctagt atttcaactt taaatgacac aaaaaagttg ttacaacaaa
     4381 aggatctaaa aaaagcggct actattatca atgaatctaa acgtgtctat tttttcggtg
     4441 ttggcggttc agagattgta gcaactgacg cttatcataa atttttgcgt tcccctatcg
     4501 caacttctca cagcacggat taccatattc aattgatgga agcttcttta ttgacggaaa
     4561 aagactgtgc tgttttgatt tctcacacag ggcaatcaaa agaaacaatc catattgctg
     4621 aaaccgtaag aaaaactgga gcaaaaacaa tcgttattac tagccaagct aattcttccc
     4681 ttgctaaact tggcgatgtc gtttttattt ctatttctga agaaacagaa ttccgatctg
     4741 aagctttagc ttcccgtatt tctcaactaa gcattttgga ctctctatat gtgattttga
     4801 tgttttacaa cgaaaaagaa tcacgtcgtt ctatcgctaa agttcgacat actatttctg
     4861 aaatcaaaga atagcaccat aacagaaaaa gcgaaaaatc cataaaacaa aaaaagccac
     4921 taccaaatat ttggtagtgg cttttttggt tctgcaaggg tggtacagaa catcaatagt
     4981 cggtgggtta gaacgtatgt catcgcatct ttggagaagg ttgtattggt attattcgag
     5041 ttacttgtta gatgcgataa caaagttagt atacagtagt aaaaaattta tcttttcttt
     5101 tttttattat ttttgtttct tattttctaa aaaattaaaa aaaattttgg tgaattaagt
     5161 atttccttga taacactggc ttttggcctc attttaggtt atcatttgta attttatttc
     5221 acagttgata tgattgttat gtaaaataaa aaagtttagg atacatcgaa tttttgggga
     5281 aattcttttg ggggtatcct aaatcttttc tattatattc ccatattttc tattattggt
     5341 ctagacgtat gatggtaaac tttgtaccta tctgattgct gaatcattaa ttgcttatca
     5401 ttagccatct ttgtttcaag ttcgctagat gatcatttta ttcacatcct aacaaacttg
     5461 tcacatttat agattcttaa tctatttatc atacaattat aaaaaaggag gtgctgctta
     5521 tgaaagctat ccatatttct ttgctttttt tcgctagtgc attgatttta tttgctattc
     5581 atctttgttc ccagccttat atcaataaca acggaatatt agtggaacca gcattctttt
     5641 gcttaccact cggctttttg tcccttcttg cctccgcagg cttcggattt gttgcttttt
     5701 ttaaacgatc aaaacaacaa atctgactta taaaatttac gtaaaagaga tcgtgacaat
     5761 aatcgtgtga tattcccaaa tttcgaataa aaggtgcccc ttgccatctc taactcctca
     5821 gtcacaagtt acaatattca taaaccatga aaagcttgtt tattgaaatt gctccttgtg
     5881 acttggagct aagtgacaga ttacaacctc ttttgcatca taagacttta ctccttgaaa
     5941 aacattacta acttttgata tgtttcttgc gcttgtttat tgctgaaatc aaactgatat
     6001 tcatggttca aaacagcatt tttctccgca taatctactt ttgtgacttt cacccccgct
     6061 ttctcaaata cagaagttac ttcttccatt tgtttcgtaa acgtatttgt atttccatcc
     6121 gttaagaatg tgttttgcgt ccaacgatcc gcatgtctga ccaaggctaa acttttgacc
     6181 ttctctgatt gttcaaagtc cttattatca aagtaagccc atccacattt ttcataaaga
     6241 aagctagaga ttttatcact tacttgagta agtgcagaag gatccaacag accagacaaa
     6301 gaaataaact tcgtaatctg cttgttctcc aaagtcggat caagatgatc agctttttta
     6361 atttcttcat tttgaagtgc taacaaatat tctccactaa tttgtgcacc tgccgaattt
     6421 ccaccaatcg aaatattcga ccaatctgct tgatctttta tctctttttt agctgcttga
     6481 atggcttcgt tcaattggat aactggtgta ggatgttttg cttccggtga tcgttcataa
     6541 tctatattta cgatgatttg ctgcgtgtct gaacatagat attccaaata atcacgacaa
     6601 tcatttttat cccctcctac atatgcgcct ccatgcatcc agaaaagaat cggtaatttt
     6661 ttcttttcca ctttcggtgt gtagatatcc atattattat ttttgtactt tgaaggatag
     6721 gatatttctt tttttatatc gatttgttcg attttttgct ggaaatcatc tggtcgggca
     6781 tatacttgtt ctttttcact tgtgtcaaat tgttttctaa caagcaagct aatcggcttt
     6841 ggtgtgattt gattaatcaa aaatacagtg actaaaataa ctacgatgat aactggtact
     6901 gcaatcacta ttcgcttgaa ccatttcatt catttaccct ctctttcttc gccaaatcca
     6961 tgtgataatc gtgctaacag ataaaaatcc acctgaataa atgagaagcg aatgtttctt
     7021 ttctccagtt ttcggcaaca ttcttttttt gcatctgtct ttttttgtac tttcactgtc
     7081 atctgaatcg gttgcgtatc atcacttgat tgatcctctc gaggttcatt ctttccctta
     7141 ttgtctgcat tctctgtcgg atcttgcttt tttggtggag ctactgggat ttttttgtaa
     7201 tagaaaataa tagttggtat cgtctcatta aaaatccctt cagtcggtcc ttcaacattt
     7261 gctaattcgt atccttcgaa tgtcttttgc tctgtcatat aattttctcc ataagctccg
     7321 taaagctgga tttcgtcctg gtctttgagt agacttttat tgttttcatc cacatacttt
     7381 acgtttatct gatcatggaa cactactttc aaaaagtccg ttacatgttt cgtgtaggca
     7441 gcatggtcaa cttcctgtgc ctttccatgc cctgctcctt ctactaataa aagatcttta
     7501 taccctcctg ataactcata taatttttgc gcgttagaca caggtactac atcatctgct
     7561 gttccatgga taatcaattt aggcaatgaa tctgacattc caatcgtagg tagagcagct
     7621 tttgtatcca aatgcatctc ctgatcaaaa tagtattgtt tcaaaaggcc cataaataaa
     7681 tcttcatgct cttgatcccc aatgatgtct aactgatttt ttatggcatc cggtagtgcg
     7741 ggggctactg tctggctgta cgtaaaacgt agttgttcat caattgatgc aaatccgcaa
     7801 ttttcaataa ttcctttgac attgacagga atatctttcg ctaatacaga catcatcgta
     7861 gctgctccca tcgaaccacc ataaagtaaa atcttttgag atggccgctc tcgaacttct
     7921 tgatttatcc agtaaaggac gtcatctgac tcatattgtc cataggtcac ataatcgcct
     7981 ccgctattac cagtcgctct ggaatcaaca aataataaat tatacccggc cttataaaaa
     8041 tcattgtatt cttctgtaac gatcccgtta ttccaattcc ctcgaaatcc gccatggatc
     8101 atgactgttt tatctgaacc ttgatcgaca taatatgcat atacatccat cattttgcca
     8161 tcttgtttgt ttagtacagt ttgatgaagt tgttttgtat ttggatagaa gcctgtgttt
     8221 tctgtaggcg ttgtcccatc atctgtacct ccaagcatcg acatcaacac actgtttttt
     8281 gcaaaagcga tatcgtacaa tagataagta gcaatcagat gtttgataat ctctttatct
     8341 acaccataat cattaacagc aagctcagtg actaataact ctattaattt tgacttgatg
     8401 tcttctgttg gtccattaag tatttctgtc atctgtttac cgaagtaatt caaatattct
     8461 ttaccattga aattttcacc tttaccgata tcatcatttt ctgtcccatt ctctttgtca
     8521 cttactttag cagaagagga ttcgtcgttt gacatttttg tagctgttgc ttcttctgtt
     8581 tgttggttat ctgtggtagc ggtcgtttct tgatctgtgc tagtaacaga tgtctcaacc
     8641 gttgtttcag tatttgtttc tgtttgtgaa gtactcgatt tcgtttcatt tccagcatca
     8701 gtagtttctg tggtttctac ctcccgagat tccgattcgg aagaaatgct ctctccatat
     8761 actgtccatt gcgggacgct tgtacttaca gcaaataaga tgaccaacgc tccctttaat
     8821 acttgttttg ttctcaagct attcactcct ttttatgttt ctaggagaat tatatgtaaa
     8881 cgcaaacatt ttttatacaa aaaataaatg gtttatccca taaaaataga acaggattat
     8941 tttctcattt tacgtaataa agcagaatgg ataaaccagt atccattctg ctttttttaa
     9001 acgaagaaac aacttattgc tccaaaaatg tcagaaatcg tttatcccaa attttctcgt
     9061 aaaaagcgat tgtttccttt gctttcataa aaggattatc ataagttgtc gttgctcctc
     9121 tacacatcat aagctggtat cctaatccat gagcaaactt cacagtcgta tctatacaat
     9181 actctgcttg tgccccacat aattcgatcg aatgacagtc caattcagtt aataaaacac
     9241 tcaaattagt cttataaaat gaattcgcat gggtttttct cacaaaataa ctgtgctcag
     9301 gaatagataa ttccgacaat agctcccatg gttttgtttg tggcactaat tgagcatctt
     9361 cgtgttgaac gaaaataact ggtttcccaa tcgtttcgta tgttttgatt cttttattca
     9421 ctaatgctgt cactgtttct aattcgtgta tcggcgaaga atcaaaacat accccttttt
     9481 gtaaatcgat cactactatt gcgtcggctg tgtttgacat acttgtgcct tctttctttt
     9541 ttcttgattt aatagtattt cttatctagc tagttccatt atacgtgaca acattttctt
     9601 attttacacc tctaaatggc acttttcgac tatttcttca tgttattatt tcataaatac
     9661 ttagctattg gaggaatgta tgatgattaa attgtataca ggttctggct gctcgtcttc
     9721 aagacgcgca aaacgttggc ttatcgtcca tgatataccg tttatcgaac agaacttaat
     9781 tcgtcaacca ctaaccaaaa atgaatttat ccacttacta aaattgacaa acaacggcgt
     9841 gaccgaaatg ctctctactc attctattag ttataaaaat cttgttcaca gaatagatga
     9901 actcagtttg agtgaactat atattgagat tcgtacatcc ccttctttat tgaaaaaacc
     9961 gattatctac gaccaatctg caaaactttt gactggattt agcgaagata aaatcaggat
    10021 gttcctttct aaaactaaaa gaaagcaaga gctcaacgaa ctcttgcttt ctggtcatct
    10081 tgtcgatttt aaagaaaata atctttttgc aatgtcttaa ttttggcata aacaatctgc
    10141 ttttcttaat taacgaaatc caatttttcc aatatggatc tatttttctc attcctgatt
    10201 tttatgattt cagctttcag acgcgcccaa tcattttttg taggttgtcc attccagtaa
    10261 aatatctgtg tattcgtttg atcatatgcc tttttgtcga taggataatc gctaatgaca
    10321 atatcaggta actgatcagc ggatgcacta tattttattg ggcgttcagt catagataat
    10381 atccttttct ttgcccataa ttcctgtgtt ttaccatact ttgattgaat atagaatatg
    10441 acaggttgtt cgtgttttat aaaaatatcc ctgactaaca tacagtattg aaaaatcaac
    10501 cgtctgttct tttcataata agtattaagc tctggaattc tgcgagctac cccactaaaa
    10561 aactgttgca tgattggata catcactgga aatatatgct gaaaatctct gtcttctgct
    10621 gattttccaa aagcatccac cttctttttt gtcccaaaaa cccttgaata caaatggatc
    10681 attgccaaat tgacatatag ataatttttt tctgaagttg taaaacaaat cttgaagttt
    10741 ttttcaaaat tttctacaat agacgattca atccagcccc aactttcttg tactttatct
    10801 ggagtatcca acaaatcttc ttccaaatag gtgttcatta caccaaacat aaaataaagg
    10861 taagcttgct ctgttggagt gatgtgattc atcgaccaga agtttgcttc aaaaaaaggc
    10921 tctagtatgt aatgcgtaaa ctcttctttt gttatcaatg gatgcacaaa tttgttcatc
    10981 tcttctggga catacgtaat cgagtggcct tgtttcattc gttgcaacga aattcttagt
    11041 aggctgatcc atttctttct atctatacta cgcgtatatg gcgcatgttt cgcaaatttt
    11101 tctaatagtt gacgtttatt ttttatactt gataatatat cagaatgatt ttcgtcgaat
    11161 gactgccaat acatcaagtg aaaaaagtat cggatacggt attcttctcc ttctatcgga
    11221 ttaccttttt tcaagctgca agataaatga tagtttttca aaatagtatt aagttctctt
    11281 aattttcttt gaatcgtacg caaacttata taattttttg actaagattt tctaaggatt
    11341 gataagtacc tttgtaaagt gaatccagta aaatataacc aatcgttccc tctaaaagta
    11401 tagaataaac tttactcagt aaaaactgag aagaaaactc gacttttatc atcttgtttt
    11461 ctgaaagaaa agataattta tattctggat acctttcgca aaacgattct gcttgttgaa
    11521 tcaccgaatt catcttagcc agggtgtagt ttagatctaa agcgatatcc ttcaccacat
    11581 ataatttctc gtctctttca taacaatagt tcaaaaattg atatacttgc ctttcattga
    11641 tatcaataaa ttcttcaaac aaagtacata ctccttttta tctattattt agacttattc
    11701 cgacagctac atgaataacg tacaaataga ttcgttactg atttttcaga gatactacca
    11761 tgcgcagtgt gcattgtcaa ttattcttgc tcttattttc catttgtgtt cctgttattt
    11821 cctgtttctc aaatatgtta gtaaacaaaa atagatctgg caaagctaca acttcgccag
    11881 gcaatacagc actctcgaat gaaatattca ctcaaaaatc tatcgtttta ttcaatttta
    11941 gatctgttgc ttttattctt tatttcactc gatggaagag agaacgaaaa tagcttgctc
    12001 ctacaatcaa aatgagtaac acacccatcc atgtaattag cttgttcaag gttctactac
    12061 cagtttctgg taaatcgctt tttctattat ctgtttcttt cgctttttct tgatgatcaa
    12121 ttccacgaga aacaaaatca ggctgtttta gcacactttt taggttgctc cctgcatttc
    12181 tcttttgttc cttagttggt atgataggta ccaaatcaag ttcattattt acttttcctg
    12241 tgctgctttc gctgctcgtg cttcctgtgc tactctcact actcatgctt cctgtgctac
    12301 tttcactact cgtactctcc gtactgcttt cgctgctcgt gcttcctgtg ctactttcac
    12361 tactcgtact ctccgtactg ctttcgctgc tcgtgttttc tgtgctactt tcactgctcg
    12421 tactctctgt actgctttca ccgctcgtgt tttctgtact gctttcacta cttgtgctat
    12481 ccgtactgct tggcggtcca acaactgtcc aactgcttgg tttcaaattc tccgtgatcg
    12541 tcatctgtcc atcataaaaa acaatcaaat caactttatc tttactcttg atctcatcaa
    12601 tcgatagttc tgcagaaatc attattgtat actcaatacc agcggtccat tgtacgtctt
    12661 ttaaataaac ttccccaata actttttctg aacttccatt accatcccaa ccatatgtta
    12721 gaacagcatg tacatcacta gcattcacgc ttttgtttgg tttgactgga atagtaatga
    12781 cttgttgtgt catgtcataa acaatccgat cagttttcac agtaaatgaa agattctcat
    12841 ttgcccgttc atttgcagaa gtactgattc caatcattgc tgcaattata ctcagcccaa
    12901 gaataacaaa taatacggtc gctgttttct tcatttctat cactctccat ataattacct
    12961 tctatttgat aaaggaatta tataaaatga aaatgatgag aacacgacag tcagttgtga
    13021 aaatctaaca aaagatgtcg tgtattcgct tgaatttgtt tactttttcg tttaatcaat
    13081 gacagactta aaaaagcaag accgatatca gccttgcttt cttcatcttt tattgataaa
    13141 cagcagtgta tttcttcatc cgctttgttt tatatgcata gagtaacaaa ccaacaatca
    13201 agactaacaa gaataatgta gttgatatag atgcttcagc cccaaagttt cccccagtaa
    13261 ttattgtatt ttgcgattgg atcagagtgg agaaaaaacc ttgttcttgc gttccgctga
    13321 ctggtatacc caaaatagct ccttgtgtcc aattccaagt aatatgagca ccaatagccg
    13381 taaataaact tcctgtactg tagataagtg cgctgaaaaa gcaacctgct aaaaagatat
    13441 tgaaaactgc cagaaatgtc atgttaggat tcaatccgtg caaaagagca aataatgcag
    13501 cagatccaat cattgctatt aacggaccaa atctaagcat ctgatgctga aaaaagccac
    13561 ggaataaaag ctcttctgat gcccccactg caataaataa aataaaactc gttatcagcg
    13621 gcacaatgtt tgcgtttcct gaatctaacc gatacgcccc cgtcaaatat aatggactag
    13681 taataagcag aaacactcca attccaacaa cgagacctcc cgctaaatac ccccagtctt
    13741 ttcctcgaac agaaacacca taatcttcta ttctttttcc ttcgacctta ctagcaagaa
    13801 ataaagctag taaaaaaaca gctaaatgtc cgaccgtacc ggcaattgct ccaatccatt
    13861 cactatttcc aataaacata tccgcaagtg cattattgac aagaattcct aaaacaaaac
    13921 caactaagac tattaaaaca gatccaatca accgaataat cctgatcatc tttcatccct
    13981 cctttatatt aagtttaaca acccttttct ttcttgtctc gtgaaaacta tgtaaatgtt
    14041 ctccatcata gagagaatag atttttacga actaagaata tctacagcaa ccttacgaaa
    14101 atgaaagact gtctccctaa ttcttctgtt agactgtttt taataaggaa aggatgggaa
    14161 attttttgaa aaaacaacta cttattatgt gcctttcagc atgtgcaatt ttactattct
    14221 caggttgtag caagtccaat gaaacgattg caacgtttaa aggtggaaca cttacagttc
    14281 aggattttta tgataaccca aaagttaaat caaataatca aacactatta aaaaaaatga
    14341 ttgtcttcaa agcatttgat gatgtatacg gaaaagagat ttcttcaaag gaagtaacaa
    14401 aagaatataa tgaacaaatc aaaaaactcg gtccaaacta caaggaacaa ttaaaagcag
    14461 ttggccaaac agaagagaca tataagaaac tctttaaaca gatgctggct ttccaatacg
    14521 gtttgaaagc caatgtaaaa ttaacagata aagatctaga cactgcttgg aaagaattct
    14581 atccagaagt tagtacacag atcattctat tttcgactaa agaagaagca gataaagcaa
    14641 aaaaagaagc aaatgaagga gaaaatttct ccaagcttgt tcaagcttat ggaaaaaata
    14701 aaacattaaa ggaaactgat ggaaaaatga attttgattc aaccaatcca gagattccta
    14761 ctgaagtaaa aaaagcagca tttaaactaa aaaacgggga agtttctgat atcattcctg
    14821 taacagatcc aacgacttat cagcaaagct attatctagt aaaaatggta aaaaaacagg
    14881 ataaaggttc taataaagac aaatacaaat ctgagctaga aaaaattgct accgaagcaa
    14941 aaactcttga tacggaattc atggataaaa caatccgtaa agtgatgaaa aaagacaatg
    15001 taactattaa agatccttat gtaaaaaata tattcaaata aacaaatttg acccaattgg
    15061 ggatgtggca aaatttgaga agtgattttt ggaaattcct tcttattttt gaggcaaacc
    15121 acttttgcca caacttcatc ggggcctttt tttatttgta ccaaaacaaa tcactggatt
    15181 tgttacaatc atgaggatat aatttaaaaa agttttttat ttctatcaca tgaatcaatg
    15241 cgccattaag tagattcttt catgcttccc tattttttca cttgccgtat cgcttcaaaa
    15301 acaactatca taaactcaaa ctcgactgaa aagttatttt aaaaaagact aaaaatatcc
    15361 cttctggact tgttcttctt attctgttat actagagaaa cacgaaagat atttttatgc
    15421 gacacttttc atttgttttt atgaaattta ttcaaaactg gcgtaacttc agagttacaa
    15481 ggatgtatta gaggttaggg aatacatcgt ttaaatgaga aataagtaat agttagtaat
    15541 agtcacccaa actttaaatt aatgaatatt gaatcgtcag atagcctcct cgagttttcg
    15601 agaaggctat cgtttatttt atggagaaat tgattcagaa gtaatcagcg acctttttta
    15661 gttcaccaat cgtttctgct tggaaagttt gcacccaatc ttcttggaag cccctcactg
    15721 ctttatcaat cgagggcatc tctaatactt gatctagtag ctctttacct aacgttatcg
    15781 catgagctcc agatcgaatg gctgtagtga cttgttcaca atttttgaaa ctagctgcta
    15841 atatttttgt tggtctttgc gtacgttcga tctcagtccg caacgaatca atcactttca
    15901 tagcatcaat gccttgattt tgcatcctgt tataataagg tgcaatataa tctgctccat
    15961 tattaatagc taaataccct tgtaattctg tgtaaatagc tgtaccggta atcaaataac
    16021 cttctttttt caactttttg atcgcttgaa ggcctgcttg attcaccggc accttgataa
    16081 acgtatcttt tcccagttct tctatgataa ctcgagcatc ctctatcatt tcttcttccg
    16141 ttcttcctat tgtctgaata tggataggaa tctgtccgat tatttttttg atttctttca
    16201 tatgcgagaa gaagtttgac gctccttctt ttttcagaat tgtaggattt gttgttacgc
    16261 ctgttaaatt caaaaactgt tgacaagaat aaatactttt tgtatttgct gtatcaagca
    16321 tgatttccat atagctttcc cccattctga tcctcttgat cgattttaat gattgtcccc
    16381 tttcttaaat gcggcatttc cttatcttct acatacattg ttcctggaag ttccggctca
    16441 tgagatccat caaattttat cgtgatatgt cctaattcat tcaaattagt ttggacaaca
    16501 tctcctactg ctgtgattac atacatttgt ttatcaaaac agagcttcat atcacaagtt
    16561 atttcttttc ttacctgatt caattcaatc ttataacaat aatctgttaa tgtttccggt
    16621 gcttcatctc caaataaaat cattattttt tctttcctga atacttctgc ttctatacca
    16681 acatctgtta caaccgtttc aaagatcgtc atctctgttc ctcctcgtaa aatatcattt
    16741 gtctaatagt ttttattcaa aatgtttcta gattataaaa tttattgaat aacacattcc
    16801 taacggaatt tgtttcgata ttgtgtgatt tctcagagta caatggatgt atgga
//
LOCUS       DAIGUC010000060        16615 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.060, whole genome shotgun sequence.
ACCESSION   DAIGUC010000060 DAIGUC010000000
VERSION     DAIGUC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.060"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="NOB46_002250"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="NOB46_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCI1059166.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="NOB46_002251"
     CDS             complement(680..1666)
                     /locus_tag="NOB46_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI1059167.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="NOB46_002252"
     CDS             complement(1689..2255)
                     /locus_tag="NOB46_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCI1059168.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="NOB46_002253"
     CDS             complement(2269..2685)
                     /locus_tag="NOB46_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI1059169.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="NOB46_002254"
     CDS             complement(3142..5076)
                     /locus_tag="NOB46_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1059170.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5357..6313
                     /locus_tag="NOB46_002255"
     CDS             5357..6313
                     /locus_tag="NOB46_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCI1059171.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="NOB46_002256"
     CDS             6403..7506
                     /locus_tag="NOB46_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCI1059172.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="NOB46_002257"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="NOB46_002257"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCI1059173.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="NOB46_002258"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="NOB46_002258"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCI1059174.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="NOB46_002259"
     CDS             complement(10887..12140)
                     /locus_tag="NOB46_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI1059175.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="NOB46_002260"
     CDS             complement(12146..13069)
                     /locus_tag="NOB46_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI1059176.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="NOB46_002261"
     CDS             complement(13290..15782)
                     /locus_tag="NOB46_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCI1059177.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="NOB46_002262"
     CDS             complement(15789..16256)
                     /locus_tag="NOB46_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCI1059178.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="NOB46_002263"
     tRNA            complement(16392..16465)
                     /locus_tag="NOB46_002263"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="NOB46_002264"
     tRNA            complement(16523..16596)
                     /locus_tag="NOB46_002264"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
BASE COUNT         4907 a         3476 c         2957 g         5275 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttga tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacgaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DAIGUC010000061        15480 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.061, whole genome shotgun sequence.
ACCESSION   DAIGUC010000061 DAIGUC010000000
VERSION     DAIGUC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.061"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..1199
                     /locus_tag="NOB46_002265"
     CDS             <1..1199
                     /locus_tag="NOB46_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI1059179.1"
                     /translation="IASNIRAIYVDEFQDTRELQYNVIAKLLQNNPQIQSMFVGDIDQ
                     AIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCYRSNQRLVDFYSNFQSCPYEIESRGN
                     NKNDRGFISYDCKVTKEDLPNIIKNIIKEKIESGIHEKDICVLAPQHYPLFSLGEYLK
                     KELPYCNFDAINISPIKVNNHSLFFKLAILYFTESGEKVRRRKLIANDILIILKNEFG
                     IEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTKHIFVNLNIDEKNYPSIFKHY
                     LFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTAHKVKGNEYDTVIAINLLNGK
                     IPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSEVGYFTSKGDLLYPTQLLDKI
                     EFDYNI"
     gene            1399..1713
                     /locus_tag="NOB46_002266"
     CDS             1399..1713
                     /locus_tag="NOB46_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI1059180.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            1734..2111
                     /locus_tag="NOB46_002267"
     CDS             1734..2111
                     /locus_tag="NOB46_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI1059181.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            2121..2894
                     /locus_tag="NOB46_002268"
     CDS             2121..2894
                     /locus_tag="NOB46_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059182.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            2916..4319
                     /locus_tag="NOB46_002269"
     CDS             2916..4319
                     /locus_tag="NOB46_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI1059183.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            4501..5685
                     /locus_tag="NOB46_002270"
     CDS             4501..5685
                     /locus_tag="NOB46_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI1059184.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            5682..5972
                     /locus_tag="NOB46_002271"
     CDS             5682..5972
                     /locus_tag="NOB46_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059185.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            5969..6190
                     /locus_tag="NOB46_002272"
     CDS             5969..6190
                     /locus_tag="NOB46_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059186.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            6232..7011
                     /locus_tag="NOB46_002273"
     CDS             6232..7011
                     /locus_tag="NOB46_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HCI1059187.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            7078..7572
                     /locus_tag="NOB46_002274"
     CDS             7078..7572
                     /locus_tag="NOB46_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI1059188.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            7628..8266
                     /locus_tag="NOB46_002275"
     CDS             7628..8266
                     /locus_tag="NOB46_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059189.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            8338..8733
                     /locus_tag="NOB46_002276"
     CDS             8338..8733
                     /locus_tag="NOB46_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI1059190.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            8717..11170
                     /locus_tag="NOB46_002277"
     CDS             8717..11170
                     /locus_tag="NOB46_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI1059191.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            11167..13194
                     /locus_tag="NOB46_002278"
     CDS             11167..13194
                     /locus_tag="NOB46_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059192.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            13191..14213
                     /locus_tag="NOB46_002279"
     CDS             13191..14213
                     /locus_tag="NOB46_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCI1059193.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            14230..15159
                     /locus_tag="NOB46_002280"
     CDS             14230..15159
                     /locus_tag="NOB46_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI1059194.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            15404..>15480
                     /locus_tag="NOB46_002281"
     CDS             15404..>15480
                     /locus_tag="NOB46_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="regulates the transcription of tet(M) by
                     attenuation; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCI1059195.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDK"
BASE COUNT         5284 a         2562 c         3045 g         4589 t
ORIGIN      
        1 atattgctag taatataagg gcgatttatg tggatgaatt tcaagatact agagaattac
       61 aatacaatgt aatagctaaa ttacttcaaa acaaccctca aattcagtca atgtttgttg
      121 gagatattga ccaagcaatt tatggatcat tagatggtat agctaaatca gttgaagaac
      181 tagaaatgct aactagtcac acttttcaat caaagacgct acatggctgt tacaggtcta
      241 atcagagatt agtagacttc tactctaatt ttcagagttg tccttacgag attgaaagca
      301 gagggaataa taaaaacgac cgtggtttta taagttatga ttgcaaagtt actaaggagg
      361 atttacccaa cataataaaa aatataataa aggaaaagat tgaaagcggc attcatgaaa
      421 aagatatttg tgtacttgct cctcaacact atcctctgtt ttcactgggt gagtatttaa
      481 agaaagaatt accgtattgc aattttgatg ctataaatat atcaccaatt aaggtaaata
      541 atcatagttt atttttcaag ttagcaattt tgtactttac tgaatcaggt gaaaaggttc
      601 gaagaagaaa gctaattgca aacgatattt taattatatt aaaaaatgaa tttggaatag
      661 aagttaaaga ttattttatt gacttagatt tattacagct aataaacagt gtgaaaagaa
      721 tgtatagtgg agacgacaac ggtgttgatt tatacaaatt tgttaccaaa catatatttg
      781 ttaatcttaa tattgacgag aaaaattacc cgtctatttt taagcactat ctatttttta
      841 ttaacgaagt agaagatcgg ataaaaaata attcattatc tagtagtgta tctagtttta
      901 agaagatgtt taaatctcga gatggtatca cacttactac agcacataaa gttaaaggaa
      961 atgagtatga tactgttatc gctattaatc ttctaaacgg gaaaattcct cattggaatg
     1021 aaatttttaa tgtttctgat aaaggaatta gttcagcgag aaaactacta tacgtaattt
     1081 gttcaagagc aaaaaataat ttatttcttt tctcagaggt gggttatttt acgagtaaag
     1141 gagacttgct ttatcccact caattattag ataaaataga atttgattat aatatttaaa
     1201 atacctaggt agtcgttgtt ttaaatatag taggaatcgg acgctcagta cggagcgtct
     1261 atttttttac ccaattttga aaggaagtga acttatgaaa ataaaaaatc aagaatcaaa
     1321 aggtcgctct ccccccttta aaaccatcac acaaataaga ttcattcaaa cataaaaaca
     1381 gaaaggatag gtaaaaatat ggaacttaaa tatgtcattc ccaatatgga aaaaacattt
     1441 ggacaattag aatatgctgg tgaagggaac attgaacaac gtcgaataaa tggcagacca
     1501 accattctct ctcgtagtta caatttatac tcaacgattc aacgagcaga tgatattgtt
     1561 gtcattcttc cctccgaagc tggcgagaaa cattttgaat ccgacgaaaa agtcaaactc
     1621 atcaacccac atattaccgc agaaggttat aaaattggca atcgaggatt taccaattac
     1681 attatgcacg cagacgatat ggtgaaagca taagaaagga aaggtgaaaa aatatgagat
     1741 tagcagaagg tattgtgatt gaaaaagacc agacatttgg cacattgaaa ttttccgcct
     1801 tgcgtcgtga ggttcgtatc cagaatgaag atggtacggt ttccgaagaa attaaagaac
     1861 gtacctatga cttaaaatca aaaggacaag gacgcatgat acaagtcagt atccccgctt
     1921 ctgttccttt gaaagaattt gactacaacg cagaagtgga attaatcaat cctgtggcag
     1981 ataccgtagc gacggctact tttcgagggg cagacgttga ttggtacgtg aaagcagacg
     2041 atcttgtatt aaaaggacag acaaaacctc atcagaaata taaaaaagaa gcgtccgaaa
     2101 gtgaaaaata ggtgttgctt atgacaaaca caccattgat tttgaaagaa attccgaagg
     2161 atgaagccat ttcttttatt cggcaatacc attattcaaa gatactccct agattgtgta
     2221 aatactttct agggattttt tcagaagaaa aattattagg cgttgtggaa ttaggctggg
     2281 gtacgcaacc cctacaaacc atacgcaaac tctttcccga cagttccctt caaaccacag
     2341 attatttaga aattggaaag atgtgttttc ttccagaaat gaatcaaacc aattattttg
     2401 gcagtcaagc tctttcagct ctaattaagt ggttgaaaga acatacggac tgtcattttt
     2461 tatatacact ggcagatgga attgagggaa aatgtggcta tgtctatcaa gcgtccaact
     2521 tcttttactg cgggtatttc aagacaagtg tctatcgtga taagcagtca tgggaaaaga
     2581 tacaccctcg aagtgctcgc cttttattag aggaaaatgc tcgctttgaa caggtagaga
     2641 aaaagcattg gctttcccag gcattttgcg aatacaaagg gattgagaaa atcaatggac
     2701 gcatgtttcg ctatctctat ccgttgacaa aagaagcgaa aaaactgtta ggacacactc
     2761 tctatcgacg tcattattat ccgaaagaaa aaaatttacg ctttgaaaag cgaatcgctt
     2821 atcagaaata tgaagccatt tctcaaccaa cttttgataa acaggctcgt atctacaata
     2881 cacaattatt ttgataggtg gaaaggagga tttttatgcc attgcttcat gacagaggag
     2941 agcgaatcaa agccaacgat aagcacttgg tctatcattt tgtactaatt tcattgctgg
     3001 tagtttttct agtcgtccta ctcccttttc attggagagc gttacaatcg gtgaactggc
     3061 aagcagttca gttagataca tttttctatc aacttcatac gccatacttt tggagcagta
     3121 ttctcactgc tctttttgta tgcggactta tcagctggct ttattatcac tatcgtatag
     3181 attctataaa acagttagag caccgtcaaa agttagctcg tatgatttta gaaaatcatt
     3241 ggtatgaagc cgaagaaact caatcagagg gattctttaa agatttaccc agcaagaaaa
     3301 ccaaacaacg aatccgccat tttcctaaaa tatattatcg aatgaaagat ggactaatcc
     3361 atattcatgt agaaatcacc ttagggaaat atcaagatca gcttttgcac ctagaaaaca
     3421 aactagaaac aggattgtat tgtgaattag tggaaaaaac gttgaaagat tcttatgtag
     3481 agtatgtcct actttatgat actattggca atcgaattgg cattgaagac gtggtagctc
     3541 aagatggacg tgtcaaattg atggaatcgg tctattggga gttcgattct ctccctcaca
     3601 tgttaattgc tgggggcact ggtagtggaa aatcctattt tattctcaca ttgattgaat
     3661 ctctcctgca tacaaatgca aagctttata ttcttgaccc taaaaatgct gatttggcag
     3721 acttaggggc ggtcatgaat aatgtctatt accgtaaaga agatatgttg gcatgtatca
     3781 atcaatttta cgaagatatg attgatcgca gtgaaaccat gaaacaacac cctaactata
     3841 aaacaggaga aaattatgct tatcttggtt tgtctgccaa ttttcttatt tttgatgaat
     3901 atgtggcaat gatggatatg ctaggtcgtg aaagtaccac cgttattcat aaactcaaac
     3961 aaattgtaat gttaggacga caagcaggct tctttttaat tcttgcctgt caacgtccag
     4021 acgcaaaata ttttagtgat gggattcggg acaactttaa cttccgtgtg gctttgggtc
     4081 gtatgtctga aatgggcttt ggtatgatgt tcggaagcga tacacaaaaa caatttttct
     4141 taaaacccat caagggaaga ggttacgtgg atacaggaaa aagtgtgatt agtgagtttt
     4201 atacacccct tgtaccaaaa aggtacgatt tcttaggaga aataggaaaa gtcattcaaa
     4261 aaaagcaatc tgagcctgta ccgcacgaag tgaaaggtac aggttcagac ttgctttgat
     4321 tggtgtggcg ttagccacgc caatccttta gccccctcta tctaacaggg gggcacaaat
     4381 acaactgaaa acaggcaatt ctcatcaacc aatgttgatg gtacaaagga ttgcggaaaa
     4441 tatgaaaggt gtaaactcaa gggtcatagt ttacatcttt tttagattgg aggtttgcga
     4501 atggaaaacg aaaaaatttg gattaaggaa ttgaaagaaa agcgactggc ttatggcgtt
     4561 tctcaaaata aactggcggt tgcttctcat attaccagac cttacctatc ggatattgaa
     4621 acaggcaagg cagtccctac tcaacaggtg aaagaagatt tactgaacgc tttggaacgc
     4681 ttcaatcccg ataacccatt ggagatgtta ttcgactatg tacggattcg attccctacc
     4741 aatgatgtgg ctcaaattat cggtgaggtt ttacgtttga atatggatta tatgctacac
     4801 gaagactttg gctattattc ttatcccgaa cactatcgtt tcggtgatat tgttgtccta
     4861 gtctctcatg atgtaagtaa aggtgtttta ttagaactga aaggaaaagg ctgtcggcaa
     4921 tttgaaaact ttctattggc tcaacatcgg agctggtatg atttctttca agattgcatg
     4981 gaacataaag gtattttcaa acgcttggat ttagctatca acgataaaac agggattttg
     5041 aatattccag atttggcaaa gaaatgtaaa caggaagaat gcatttccgt ctttcgaagc
     5101 tttaaaaatt atcgcagtgg tgaattggtt caccgtgatg aaaaaccata catgggaaac
     5161 acactttata ttggctcatt aaaaagtgaa gtctatttct gtatatatga gaaagattat
     5221 gagcaatacg tgaaaaatga tgttccctta gaagacgcag aagtaaagaa tcggtttgaa
     5281 attcggttaa aaaatgaccg agccacccaa gccatgaaag atttattggc acatcaacag
     5341 gcggaaaaaa cagcctttga aattatcaat cgctatatcc gctttgcaga taaagacgac
     5401 actaaacgtc ggagtgattg gaaaactaat gaacgttggg aatggtttat cggtaaaaat
     5461 cgtggagcat tacgcctaac cacacagcca gagccttatt cttttgaacg aacattgaac
     5521 tggttacatc atcaagtcgc ccctacatta aaaatcgcaa gcattttaga tgttctcaac
     5581 ggtacaacca ttatctccac catgattcag gaagccaaac tgacagaaaa acatgagaaa
     5641 ttaattgaac aacaacatct agccatggag gatttgatta catgagcctt ttaacaaaag
     5701 aattaaagaa gttagggttt cagtgtggca ttgagtttca agcgtatata caaaatacag
     5761 ggaaatatac gtctctcatt attgagggaa aacggcaagc tggtgatacc atctatacct
     5821 atgattttta caaggtgaga ttttataata attataccaa tcgagtaacc gtctatggag
     5881 agcatttaac cccttttcaa ttattaaggc gtgtaaaaag ctatatctat tatcgagaaa
     5941 aatatcttaa ggaaaggagg acaatcacat gaattttggg cagaatttgt acaactggtt
     6001 cttggataat gcacagtcat tggtattgtt agcgattgtt gtcattggac tgtttttagg
     6061 ttttaaacga gaattttcaa aactcattgg cttcttgatt attgctctaa tcgccgtcgg
     6121 acttgtgttc aatgcagctg gcgtgaaaga tgtgttatta aacttattta accgaatcat
     6181 tggtgcttaa cagatatttt tcatgataaa ataggaagta tatattttgt tatgaaagga
     6241 tttatgaata tgtttacaaa tgatcaattt aaatctcttt taattaaaac attagaaaga
     6301 aagagctctt caaattatta tgaaggaggt aacgagattg tttctaaaat gaaaatatca
     6361 gaggtaactt tagatgagac tgacgatttt acttattata aaggatataa aaagggctgg
     6421 aatacgcttt gcacatatct taaaataaga gttccttttg atgatttaga cttttttgaa
     6481 agtcataaag atttgattac ccagacagca agctccatat atgataaaca aggtgataat
     6541 gtattagtgg atactatttt agtaccactt ccagagaatt acgaagtaat taactttagt
     6601 cagttgaaaa ttagtgatgt ggtttcacaa gctattgaag acgctgagtc ttttatgagt
     6661 aatggtgaat atcaacgtgc ctttgacaga gttcacactg cttttcatgg atatttaatt
     6721 gaaatactaa aaaaatatga aattacagtt cctagagacg aaaatctatc taaattatat
     6781 agtaggatac aacaattaat tgaaaaagaa attcaaccta ctgaacttgc tgatatagtg
     6841 aagacaacga taaggtcatc aaatggaatg attagctctc ttaatgaagc aagaaatagg
     6901 cattcacttg cacaccctaa tacaaatatt attggaaaga gagaagcaaa actaataata
     6961 ggtatttcaa gtacagttac agattatatt agcggatacc ttgataagta gcgtcattaa
     7021 ctgattgcta ctttttttat gactattttt ataaaaagga tgtgataaga attggaaatg
     7081 aaagtctatg tggcaaattt aggacggtat aatgaaggtg aattagtcgg agcatggttt
     7141 actccaccaa ttgatgagga agaaatggca gaaagaatcg gtttaaatga ggactacgaa
     7201 gaatatgcaa tacatgattt tgagcttcct tttgatgtgg acgaatacac gccgattagt
     7261 gaaatcaacc gtctatgtga agccattcaa gaaatcgaag gtacacctat ttataatgaa
     7321 ctcaaagaaa ttcaaggcat gtggtttagt agcttggaag aattactgga aaacaaagag
     7381 gatattcatt gttatagtga ttgtgattcg atggaagatg tcgcccgtta ttacgtggaa
     7441 gaaacaggac agcttggtga agtcccttcc aatttacaaa attatattga ctaccaatct
     7501 ttgggacgtg atatggaaat agagggtaat tacctagtta cctctcatgg ggtatttgaa
     7561 tattgtcagt aagtttaaca atccgtgtta taattaaatt aataaatagc acggagaggt
     7621 ataaattatg gtaaatgtat ttgaaaatct taaactatta aaactagaca tgaaagataa
     7681 aggctgggtg atagattcct tttactttcg ttacaaacag caaaattata ttgtacttgt
     7741 taagctattt gaaaaagagg aaaaagttcc agaatatgct ctgttaaaac tagaattttt
     7801 aaaggaaaac gatttttcag atatgctagc tgtctatgct aattcggtaa aattatatac
     7861 agacacgaaa acaataagag aatattttgg tatcgaatac agtagtaact tgggagatgt
     7921 tttatttcaa tttagccaaa ctcttgctcg atttattccg acagaagtta gtgagaagaa
     7981 aaatgaagac caaaaagaag ccatgtgttt ctcattaagt caaagtgatt cagaagatcc
     8041 cagaaaaaaa tattgttttt cagttagaag aaatccttta aagggaaatg gtgagctggg
     8101 aaaacgaagt ccttttaatg acaataaaac gagattgtat agacccagct tatatgaacg
     8161 attagggtca gataccaatt taagtttcag atattcaatg aatccagatg atgaagaaac
     8221 tgatgaaggt attattgcaa aatggacaaa aaataaaatt gaatagttaa agcattgaaa
     8281 gagcaatcac ctattttgat tgttcttttt ctatttttac ggaaaggacg tgaagacatg
     8341 aaaaaaataa gaagttacac cagtatttgg tcagtagaaa aagtgattta tgcgattaat
     8401 gatttacaac tccctttccc aattaccttt acgcaaatga catggtttat cgtttctttg
     8461 tttgtcgtca tactctttgg cagtttacca ccactttctc tgattgacgg agcactactc
     8521 aaatacttag ggattcccat tgttctcact gggttcatgt gccaaaagac ctttgacgga
     8581 aagaaaccct atggatttct aaagtctatc attacctatg ctctacgccc taaagtaacc
     8641 tacgctggca aacaaatacg attaaaaaaa gaaacaatga atgaatcgat tacgattgta
     8701 aggagtgaac aactagatgg catatccgat taaatatatg gaagataatc tcgtatttaa
     8761 tcatgatggc gaagtattcg cttattatga attaattccc tataattaca gttttttaag
     8821 ttccgatgaa aaaattcaag ttcatgataa tttctgtcaa ttgattgccc aaaatcgtga
     8881 tggcaagatt catgctctgc aactagcaac cgaatcaagt attcgagcca cacaggaaca
     8941 atcgaaaaaa gaaatcactg gacgattaaa agagatagct tacgaaaaaa tagatgaaca
     9001 gaccgaagcg ttaatttcta tgattggtga caatcaagta gactatcgct tttttattgg
     9061 ttttaaactc tacctcaatg aacaggaagt atccgtaaaa aatgttggga aagaaattca
     9121 aaaagcattt gcggaattct ttcatggtgt gaatcacaaa ttaatgggcg attttgtttc
     9181 tatgcctatg gcggaaatcg aacgcttttc taagatggaa cagttgttag aaagtaaatt
     9241 atccagacgc tttcagattc gtaaattgga gaaagatgat tttggttata ttattgaaca
     9301 tctttacggg caaacaggtg tcccttttga tgactacgac taccatttac cgaaacgata
     9361 cgaagataaa aaagtgttgg taaagaaata cgatattctc aaacccactc gctgtttaat
     9421 cgaagaaaat caacgctatt tacggattga acaggaagat accactactt atgtggcgta
     9481 ttttacaatt aatagtattg ttggtgaatt ggatttccct aatagtgaaa ttttttatta
     9541 ccagcaacag cagtttactt tccccgttga taccagtatg aatgttgaaa ttgtcgccaa
     9601 taaaaaagcc ttatctaccg ttcgcaataa aaagaaagaa ctgaaagatt tagatagcca
     9661 cgcatgggaa agcgacaacg aaaccagtac taatgtggtg gacgctttag aatctgtcga
     9721 tgaattagaa agtaatttag accaaaccaa agaatctatg tacaaactaa gctatgtggt
     9781 acgggtatca gcaaagaatt tggacgagct gaaacaacgt tgtgatgaag taaaagattt
     9841 ttatgatgat ctgtctatca aattagtacg accttttggc gatatgctag gcttgcataa
     9901 tgaatttatt ccctcaagca agcgatatat caatgactat attcaatatg tcacgtcgga
     9961 ttttttggct ggtcttggtt tcggtgctac acaaatgatt ggtgaaaatt ctggtattta
    10021 cgtcggttac aatctcgata caggcagaaa tatttatctc caacctagcc ttgcaagtca
    10081 aggaattaaa ggctctgtaa caaatgcatt agcgtccgct tttattggtt cattaggtgg
    10141 cggaaaatca ttctctaaca atatgctggt ctattattca gtactctttg gcggacaggc
    10201 aaccattgtt gacccaaaag ctgaacgtgg tgaatggaaa gaaaccttac ctgatattgc
    10261 ccatgaaatc aatattgtta atctcacgag tgagaacgac aataaagggt tacttgaccc
    10321 ttatgtgatt ttaaaactcc cgaaagattc agaaagcctt gccattgata ttctcacgtt
    10381 cttaacaggt atttccagcc gagatagcga gaagtttcct gtcctgcgta aagctattcg
    10441 gagtgtaact caaagcaaac aacgagggtt gttattggtg attgatgaat tgcgaaaaga
    10501 agatacgccc atcagcaata gtattgctga ccatatcgaa agctttgtcg attatgattt
    10561 tgcccatctg ttattcagtg atggcagtgt cacccaatcc attagcttgg aaaaacaact
    10621 caatattatt caagtggcag atttggtctt acccgattcc aatagctctt ttgaagaata
    10681 cactaccatg gaattattaa gtgtggcaat gctgattgtc attagtacct ttgctttaga
    10741 ctttatccac tctgaccgtt ccatttttaa aattgttgac cttgatgagg cttggagttt
    10801 tttacaagtg gcacaaggaa aagctctatc tatgcgattg gttcgagcag gacgtgccat
    10861 gaatgcaggg gtctatttcg ttactcaaaa cgcggacgat ttactagatg aaaagatgaa
    10921 gaataatatt ggcttgaaat ttgcctttcg ttccactgac ctagtggaaa tcaaaaagac
    10981 cttagaattt tttggtgtgg acaaggaaga tgaaaacaat cagaaacgct tacgtgaatt
    11041 agaaaatgga caatgtttag tttcagacat ctatggtcgt gtaggggtta tgcagtttca
    11101 cccgattttt gaagagttgc ttcatgcctt tgataccaga ccgcctgtgc gaaatgaggt
    11161 ggaagaatga cacaaaaaca aaagaaattt cttcactata gttggataac gctcctttgt
    11221 gtgggcgtta ttttactttt attaggcacg ctgggcaatg cagtacaagc gacaggctta
    11281 gttgatgaaa ccattgatac aagcaatgaa tactccaagt atggtttgaa tcaatatcag
    11341 cttgattatt atgtggacaa tagctggggc tggcttccat ggaattggag tgatggcata
    11401 ggacaatcgg tgatgtatgg attgtatgcc attactaatt ttatttggac aatttctctt
    11461 tatctatcga acgccacagg ttatttggtg aaagaagcct atgccttaga tttcattagt
    11521 caaacatccc aagcaattgg cgaaaacatg cagacgattg caggcattac accgaatggc
    11581 ttttccagtt cagggtttta tgtcggtttc ctccttcttt ttattctcat tgttggaatc
    11641 tatgttgcct atacaggatt ggttaagcga gaaacgacga aagtgatacg agctgtttta
    11701 aactttgtcg tggtgtttat tctatcggct tcctttattg cgtatgcacc cgattatatt
    11761 gcgaaaatca atgatttttc caaagatgtc agtaccgcca gtctgaatat tgggacaaaa
    11821 attgttcttc ctaacacgga tagtcaaggg aaagacagtg tggacatgat acgtgacagc
    11881 ttattctctg ttcaagtaaa gcaaccatgg ctattgcttc aatatggctc cactgatgta
    11941 gaagcgttag gggaagaacg tgtggaaagt ttattgtcta ccagtccaga tacaaacaat
    12001 ggtgaagata gagaaaatgt agtgattgaa gaaattgaag atcatgacaa tacctattta
    12061 accctaccga agacgatttc cagattagga acagtcttct ttttgtttgt attcaatatt
    12121 ggtatctcga tttttgtttt ccttctaaca ggaatcatga ttttttcgca agtgctattt
    12181 attattttcg ctatgttttt gccaatcagt ttcctattaa gtatgttgcc gagttttgat
    12241 ggcatgggca ggcatgccat taccaagtta tttaatgtga ttatgacaag ggctggtatt
    12301 accttgatta ttaccgttgc ctttagtatt tccactatgc tttattcgct gtcagcaagt
    12361 tctccctttt tcatgattat gtttttacaa attgtgacct ttgcagggat ttattttaaa
    12421 ctgggcgatt taatgagcct attcacttta caaagcaacg actctcaaaa catgggcaga
    12481 caagtgtttc gcagacctcg tcaaatgatg aatcgacaaa ccagaagatt tcaacgcagt
    12541 atgagtaaga tttttcgtgg aaaagcaggg tcaacgaagc aaaagacaat gacaacaaag
    12601 cagaatcaaa ccaataaagc taaccatact cgtcaaaatg aacggactac accaaagaaa
    12661 gaaacagcac tttccaatgt gaaaaagcaa caaggcggta tcgggcaacg attaggtgaa
    12721 aagacagccc atgtattgga cacgaaaaat cgtctagtca ataaaagaaa gcaggcaaaa
    12781 caacagatac aggcgacacc aacccatgtc aaatatgccc ttcatcaagg aaaagagaat
    12841 gtcactcata atgtaacaga ctttaaacaa tctatggcag ataccaaagc tcaacgcaaa
    12901 caacagcgta tgaaccagca ggagcaaaaa cgaaagaaca ttgctcaaaa gcgtttggag
    12961 ctggataaag caaaagaaaa aagacgaaaa gaaaacccat catctcctgt tcagaataac
    13021 cagcagcatg ttcgcaagcg tcagcaaacc gtcacgcctg ttttgtcaca aaacactaaa
    13081 cgtgaaaatc atcagcgacc attgaaaaaa gagcaaaaac aaaagacacc accgaagcaa
    13141 ttcaatcaga ggaagctaaa taaaagaacg gataagcgag gacaacaaac atgaagctaa
    13201 aaataacagt gatttgtagt gtggtcttct ctctcttctt ttttctctta ttattcctag
    13261 tcattttctt tgcagatgat acggacagtg gcgaaaacaa caaggattct tctattccac
    13321 aaggcggtgt gaccgtttca ccagaagtgt tggcacaccg tccgttgatt gaaaaatatg
    13381 gtaaggaata tgggattgaa gactatgttt cttatatctt agccattatg caagtggaat
    13441 cgggcggtac agcagaagat gttatgcaaa gttccgaatc tttgggttta ccgcccaaca
    13501 gtttgagtac cgaagagtcc atcaaacaag gggttaaata tttcagtgaa ttattaacca
    13561 gtgcagaaca acaaggagtg gatatagatt ctgttatcca atcttataat tatggcggtg
    13621 gctttttaaa ttatgtgagg agtcatggga aaaaatatac ctatgaatta gccgaacagt
    13681 tttctaaaga gaagtcgggt ggtcaaaaag cagactatcc caatcctata gccatacctg
    13741 tgaatggtgg ttggcgatat aactatggaa atcagtttta tgttcagttg gtttcacaat
    13801 acctaaccga cacttcccca acagaatttg atgatgaaac cgtgcaagtc attatggacg
    13861 aagccttgaa atacgaaggg tttccctatg tctttggagg ggcgtcgcct accacctctt
    13921 ttgattgtag tggcttaata caatgggtgt atgacaaagc tggcatttct ctccctcgtg
    13981 tcgcccaaga tcagtatgac gctacgcaag aaatctctat ggaagaagcc caagcaggcg
    14041 accttatctt ctttcattca acctataatg caggcacata tgtgactcat gtggcgatat
    14101 atttagaggg aaatcgcttt tatcatgcag gcgacccaat cggttatggc gacttaagca
    14161 gtcgttattg gcaagaccat ctgattgggg ctagacgtgt tattcataac taagaaagga
    14221 atgaatcaaa tgattataaa aatcgagcga aaagaaaaga aggagaaacc aaagaaatct
    14281 aaaaaaccga gcaagcaaag aaaagttccg atgattaaag ttggcacgca taagaaatta
    14341 acctttgttt tatgggtttt attgattggt agtgtcggat ttggaatcta taaaaatttt
    14401 actgccattg acactcatac tgtccgtgaa acagaaatca ttaaacagca gattgtcgat
    14461 accaaccaag tagaaagttt tgtgaaatcc tttgcgaaag actacttttc gtggcaacaa
    14521 tcccaagaag ccattgataa acgaaatgaa aaattgaccc attatttgac ggaagaattg
    14581 caggtattaa atgaagaaat gattcgtaag gatattccta ctagttctag tgtgaacgat
    14641 atacaggtgt ggcaggtttc tcaagtgaat gagaacacct ttgaggtact gttttctgtt
    14701 gaacaagtta ttaccgaaga caaagacaag gaaactatat cgtctagctt tcatgtggtt
    14761 gtccatatag atgaatcaga taatatggtt attatcaaaa atccgacaat gagtaagaaa
    14821 cctcaaaaat cggactacca acccaaacag ctagaaagtg accatacagt agatacagaa
    14881 acgatggacg aaatcactag ctttttagaa acgttcttcc agctctatcc taccgccaca
    14941 gaaaaagaat tgacttacta tgtaagtaat catgtgttac ctatgattaa caaggaatat
    15001 gttttcgagg aattggtgaa tcctatcttt accagaaaag ataaccaagt aatcgtgaat
    15061 gtcgctgtga aatatttaga tcaagaaaca aaggcaaccc aaatctcgca atttgagttg
    15121 atattagaaa aacaagataa ttggaagatt gtaaaataac aaatattggt acatgattac
    15181 agatactttg taatcatgta ctctttttga taaaaaattg gagattcctt tacaaatatg
    15241 ctcttacgtg ctattattta agtgactatt taaaaggagt taataaatat gcggcaaggt
    15301 attcttaaat aaactgtcaa tttgatagcg ggaacaaata attagatgtc cttttttagg
    15361 agggcttagt tttttgtacc cagtttaaga atacctttat catgtgattc taaagtatcc
    15421 agagaatatc tgtatgcttt gtatacctat ggttatgcat aaaaatccca gtgataaaag
//
LOCUS       DAIGUC010000062        14939 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.062, whole genome shotgun sequence.
ACCESSION   DAIGUC010000062 DAIGUC010000000
VERSION     DAIGUC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.062"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..1235)
                     /locus_tag="NOB46_002282"
     CDS             complement(<1..1235)
                     /locus_tag="NOB46_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCI1059196.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQK"
     gene            complement(1228..2820)
                     /locus_tag="NOB46_002283"
     CDS             complement(1228..2820)
                     /locus_tag="NOB46_002283"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCI1059197.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(3330..4055)
                     /locus_tag="NOB46_002284"
     CDS             complement(3330..4055)
                     /locus_tag="NOB46_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059198.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(4209..4535)
                     /locus_tag="NOB46_002285"
     CDS             complement(4209..4535)
                     /locus_tag="NOB46_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059199.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(4572..4937)
                     /locus_tag="NOB46_002286"
     CDS             complement(4572..4937)
                     /locus_tag="NOB46_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCI1059200.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(4974..5189)
                     /locus_tag="NOB46_002287"
     CDS             complement(4974..5189)
                     /locus_tag="NOB46_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059201.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            5318..5653
                     /locus_tag="NOB46_002288"
     CDS             5318..5653
                     /locus_tag="NOB46_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059202.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(5729..7726)
                     /locus_tag="NOB46_002289"
     CDS             complement(5729..7726)
                     /locus_tag="NOB46_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059203.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(7824..8099)
                     /locus_tag="NOB46_002290"
     CDS             complement(7824..8099)
                     /locus_tag="NOB46_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059204.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            8331..9065
                     /locus_tag="NOB46_002291"
     CDS             8331..9065
                     /locus_tag="NOB46_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059205.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            9104..10246
                     /locus_tag="NOB46_002292"
     CDS             9104..10246
                     /locus_tag="NOB46_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI1059206.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(10580..11491)
                     /locus_tag="NOB46_002293"
     CDS             complement(10580..11491)
                     /locus_tag="NOB46_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059207.1"
                     /translation="MGERTFEDVKDYVELQSQEKCTVLSAKPEQEFNDLGTEVTVWNV
                     KTDTDGDWWVVEGDNVPMNLYPQSAYYFGTDEVYSFHMGLMERMRVLHEKYDPEDFVR
                     SVTLDTEIAPQLFRKLKNVATLIDSAEEIEDFQSIGVQCREILIELGNHIFIADMAGT
                     KEQPQKSNFKKKAELFIQFYLTGSDNSDYRSIIKKLTESTWDYANKLTHSSTTTKYEA
                     STCVMLVTSLVGVYENITQKVFDPVSQYICSSCKSKKLTIDSDDSDENGMVESLYLKC
                     EECGDITKVVFLTSDKDSSYTKGKIIE"
     gene            complement(11596..13026)
                     /locus_tag="NOB46_002294"
     CDS             complement(11596..13026)
                     /locus_tag="NOB46_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059208.1"
                     /translation="MDDIKEVFLEVLSRYIQDNLLEYQNNGKKYEFSFDIKNYNDSLH
                     VVFQYNKAGKIGITDVHSFQIFLNEINIEASKSHLNYTTILDTNSLFFSKKLLPYLHS
                     YEWALRKLIYLLAPTYFDNWTKDSIPDEMISAVKGKQKQAIGKYDLENLLQWIDLYDF
                     EEYLFGENYLFISTGNEKNIVRYKEIIVEELLNLFRETDDLSLSDPFSLWSEVFSKYM
                     YVDLEEIRKDMELIREGRNIVSHNKEIKYSLYKDLIKNLKKYVKQLNEAFKKILIGEI
                     ADEKLFDMTNDFEAYIGNHYSNINLPNATKLLTSLSAMTVLNTDSTKKMMETIGPALS
                     VQRAVMQNIDTEGFRRATEGMKQSLSAMTVLNADSTKKMMETISSALSAQRAVMQNID
                     TEGFRRATEGMKQSLSAMTVLNTDSTKKMMETIGPALSAQRAVMQNIDTEEFRRATER
                     MKQSLSPKQALKSDYKIADDIEDSNK"
     gene            complement(13195..14124)
                     /locus_tag="NOB46_002295"
     CDS             complement(13195..14124)
                     /locus_tag="NOB46_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059209.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHVRNYSQHGHLPVNIE
                     QQRVYFDLDEILTMPHFDLNEKLKSEIDEIKEDISARFEDFPRISYVYTIAKFNLITT
                     EIYLNYLKEVKPILMEMDKEKNELLLNTKFKLTNSDGKSSDVVFYDFDGENYHCFNRT
                     DNSLSMYASIKKEVKKILREEEQYYKEIKNKNQ"
     gene            complement(14372..14722)
                     /locus_tag="NOB46_002296"
     CDS             complement(14372..14722)
                     /locus_tag="NOB46_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059210.1"
                     /translation="MIFENESEEIGRVAEENKVDPLETLVINKKEFEQLFLDFFIQYD
                     MIYDFSSSLDLFELEAEIIENSREKNGKIIISVEKFNELFSETFEIDPDYYQPQEVFR
                     EFRNQIIRSSNIEN"
     gene            complement(14763..14909)
                     /locus_tag="NOB46_002297"
     CDS             complement(14763..14909)
                     /locus_tag="NOB46_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059211.1"
                     /translation="MILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFTL"
BASE COUNT         4750 a         2795 c         2095 g         5299 t
ORIGIN      
        1 atcttttgta agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
       61 gcgatcgtgt cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc
      121 ctagtaaaag gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt
      181 ccttcagtgt tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg
      241 aactcattat ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc
      301 gtcataccaa gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg
      361 aattcatttg gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca
      421 tcaaactgtt ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag
      481 tctaaatctt tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt
      541 tcccaatctt ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg
      601 aacatttttt gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga
      661 agagcgatag tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat
      721 attggaaatt gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct
      781 gaacctggat tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata
      841 aaatattctg aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat
      901 acacccggtt ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc
      961 atgataaaat cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta
     1021 attttatatc ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa
     1081 ttgctattag atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact
     1141 ccatcttttt tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct
     1201 gggaaacgaa tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg
     1261 taaccacgct tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt
     1321 ttctagcact tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc
     1381 aattggttct tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt
     1441 ttctttgatt tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc
     1501 ataggtttcg aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt
     1561 gacaaattct cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa
     1621 tacaatcacc gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac
     1681 agcataaata ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg
     1741 gaataaaact ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa
     1801 accatgaaga agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt
     1861 aaaccgagaa tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt
     1921 cattactact gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc
     1981 cccattgcgg agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc
     2041 tagattgtat gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt
     2101 taagtagtta cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact
     2161 aaagaatcgt cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat
     2221 atgaggcgtg taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag
     2281 aaattcataa gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa
     2341 tttcttaatg acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt
     2401 tgattggaga tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg
     2461 cacaaaggct ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa
     2521 gacgttgaaa agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat
     2581 cagatcttct tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct
     2641 taccgtatca tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg
     2701 gtcggataaa tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc
     2761 cattttgcta cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa
     2821 aaagatacac tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc
     2881 ccttttagaa aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga
     2941 aaggagtcta acgttgtttg atataactta gactgatcgt taacttattt tttatatttc
     3001 tacatagtta tctttagaac catttcagat acatatgaaa caattacata tgattttttc
     3061 ataaaaaaac agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac
     3121 taaaatcact acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct
     3181 ccgtttcatt tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc
     3241 cagtagctta tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg
     3301 gtaaataaat gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg
     3361 taatcagtta cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt
     3421 aaccgaagtg gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga
     3481 ttagctaata aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc
     3541 gtgattcctt tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct
     3601 acaaatgaat taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct
     3661 gtatatatgg cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca
     3721 ttagttagta aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc
     3781 ctaacagctt taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct
     3841 tccataaacc ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct
     3901 ttcatttctg agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc
     3961 tgattcgttt ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt
     4021 gccaaacaaa tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat
     4081 aacagtgact aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca
     4141 aaaaaactcc ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata
     4201 catttaaatc aatttaacat taacacctca gtatatggta tctctacata tacacggtct
     4261 ttttttggat agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta
     4321 gcccggtacg tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt
     4381 aagttatact gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca
     4441 gatgaacccg tcattcttga aaaaattata cctataatag ccaatacaac gatacctata
     4501 atgacaaact tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg
     4561 attttctctc atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct
     4621 acccctgcta tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc
     4681 ataataacag caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa
     4741 atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc
     4801 atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct
     4861 gtttcttgta atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca
     4921 cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg
     4981 tttactttat taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa
     5041 agcattttca tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat
     5101 tgctgtgtaa cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg
     5161 tatcggctga gattacttac ttttttcatg attctcccct cctgttttat tatatacaac
     5221 aatatgatgt atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa
     5281 caacttgttg tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa
     5341 ggtcattaga gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat
     5401 cttctctaca caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga
     5461 tagcttaaca gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt
     5521 tgacatagat tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc
     5581 aattcgaaca attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct
     5641 attgaaagat tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa
     5701 ataagattaa gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc
     5761 ttactctccg tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa
     5821 ctcctgataa tatcaattct tttattactt catctatccc tgcccctttc gctagatata
     5881 ctaaaaaact actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt
     5941 caagagtgaa tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc
     6001 tgttatccct gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca
     6061 ttagatatgt cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca
     6121 attgtttttc cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt
     6181 tttcgttaaa acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt
     6241 tttccagaag tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa
     6301 cgtctaatcg atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct
     6361 ttaacctatt taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta
     6421 tcaatcctat aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt
     6481 taccatagta agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac
     6541 tttccttact atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca
     6601 tttcctctag ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt
     6661 caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt
     6721 tctctaatag ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa
     6781 ctccaataaa attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc
     6841 cagttttact ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta
     6901 agtttttact tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct
     6961 cattaaaaga catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt
     7021 ctttgtcgtc attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc
     7081 tccctgaatc actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag
     7141 taatatctaa catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa
     7201 aaaacattct attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt
     7261 attcgtaaac agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa
     7321 tcttgtattt ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat
     7381 tatgaactaa attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac
     7441 tcaaatctac taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta
     7501 ctctggtttc cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa
     7561 atgattgtga tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat
     7621 ctaaacacct atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt
     7681 tttctttatc tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct
     7741 tataaaattc tgttaaagac taaaacatac agataataaa aacaaactct ttattactat
     7801 atgttttagt cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca
     7861 gattttttaa atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca
     7921 tattttctaa tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata
     7981 tactctagag tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc
     8041 tctttcactt gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata
     8101 tttccccctc ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt
     8161 tctcaaaata aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt
     8221 catcgacata cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat
     8281 ttacaacacc ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac
     8341 gtccaccaat aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa
     8401 gaaagagtaa aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa
     8461 ttgacaaaaa gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat
     8521 tatcccgaat tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag
     8581 aagaatatat tttgggaatt attctttata gagatagcat tgtactagat ggtataacat
     8641 ttccagataa aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt
     8701 tagatacatg gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta
     8761 acaagacttg taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag
     8821 aagaattatt catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta
     8881 gcagtataga agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag
     8941 acatgtctta tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac
     9001 aaacgatttc atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca
     9061 tctagtggta agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa
     9121 gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc
     9181 acgaactggt gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca
     9241 aaaagattat gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga
     9301 tatgacattt gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc
     9361 ttcaacaatc gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa
     9421 gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag
     9481 taaatatgaa agttacgatt atatgagaaa acagactgca caaattttac gctacggggt
     9541 tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga
     9601 gtatgagaaa aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt
     9661 taaagatttt ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat
     9721 gagaaagagt gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact
     9781 acatgtcaat aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa
     9841 aacaagagct tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa
     9901 ctggaaatta cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga
     9961 gcaacatgtt tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg
    10021 gttaagatat attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca
    10081 tacacatgct agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt
    10141 agggcatgaa aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc
    10201 taagaaaaca ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa
    10261 atctggtcat ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg
    10321 ttctagctcc tataacaggt ttacccaaca ctgccttcca atgactcttt tcaatagcat
    10381 tggtacatga ttcgcgttat aaaagcattt ttcccgctct ggtatatatc actgacagcc
    10441 tatcacagca cttgatatcc cccagaacgt atccaatatc gtacccaaaa aagcaggtag
    10501 agaagttatt tgaggtatca aatttaaaaa cgtgtgcact ttgaattgcg tgatatgttt
    10561 ttgacatgat ccataatcat tactcaatta tttttccttt tgtgtatgaa ctatccttat
    10621 cactagtcaa aaatactact tttgtaatat caccacattc ttcacatttt aaatacaagg
    10681 attcaaccat tccgttttca tcagaatcat cagaatctat cgtgagtttt ttacttttac
    10741 acgacgaaca tatatactgt gagacaggat caaagacttt ttgcgttatg ttttcataca
    10801 caccaaccaa agacgttaca agcattacgc aagttgaggc ttcatactta gtagttgtac
    10861 tagaatgagt taatttatta gcgtagtccc atgttgattc agttagtttt tttataatac
    10921 ttcgatagtc agagttatcg gaacctgtca aataaaactg tataaaaagt tccgcctttt
    10981 ttttgaagtt tgatttttgt ggttgttctt tagtacctgc catatctgct ataaagatgt
    11041 gattaccaag ttcgattaga atttctctac actgaacacc aatagattga aaatcttcaa
    11101 tttcttctgc actgtctata agagtagcaa cattctttag cttccgaaag agttgtggtg
    11161 caatctctgt atcaagagta acgctcctta caaagtcctc tggatcatat ttttcatgta
    11221 aaactctcat tctctccatt aaacccatat gaaacgaata tacctcgtct gttccaaaat
    11281 agtatgcact ttgcggataa aggttcatag gaacgttatc accctcaaca acccaccaat
    11341 cgccgtcagt atccgttttg acattccaaa ccgttacttc tgtaccaaga tcattaaatt
    11401 cctgttccgg cttggcactt aacaccgtac acttttcttg gctctgcaat tctacatagt
    11461 ctttaacatc ttcaaaagtt cgttcaccca ttatttacct ccatgatttt taccaaatag
    11521 attgtatttt tctagtttta tttcacctct ctaattcttt taatagttta ttaattggaa
    11581 aaagttctgg actctttatt tattactatc ttcaatatca tcagcaattt tataatcgga
    11641 tttcaatgct tgctttggtg atagagactg cttcattctc tcagttgctc gtctgaactc
    11701 ctcagtatca atgttttgca tgactgctcg ttgagcggat aatgccggac cgattgtctc
    11761 catcattttt ttagtagaat cagtatttaa tactgtcatc gctgatagag actgcttcat
    11821 tccctcagtc gctcgtctga acccctcagt atcaatgttt tgcatgactg ctcgttgagc
    11881 ggataatgcc gaactgattg tctccatcat tttttttgtg gaatcagcat ttaatactgt
    11941 catcgctgat agagactgct tcattccctc agtcgctcgt ctgaacccct cagtatcaat
    12001 gttttgcatg actgctcgtt gaacggataa tgccggaccg attgtctcca tcattttttt
    12061 agtggaatcg gtatttaata ctgtcatcgc tgataaagac gtcaataatt tagtagcgtt
    12121 gggtaggttt atattactat aatgattccc tatatatgct tcgaaatcat ttgtcatatc
    12181 gaaaagtttt tcatctgcta tttcaccaat tagtattttc ttaaatgctt cattaagttg
    12241 tttcacgtat ttctttagat tctttatcag atccttatat aaagagtatt taatctcttt
    12301 attatgactc acaatattcc ttccttctct gatcaattcc atgtcttttc gaatttcttc
    12361 taaatcaaca tacatatact tgctaaatac ttcactccat aatgaaaaag gatcagatag
    12421 acttaaatca tcagtttctc gaaataaatt taacaattct tctacgatta tctctttgta
    12481 ccttacaata tttttctcat ttccagttga aataaatagg taattttctc caaataggta
    12541 ttcttcaaaa tcgtataaat ctatccactg taaaagattt tctaagtcat acttgccgat
    12601 tgcttgtttt tgttttcctt ttactgcaga aatcatttcg tctggaatag aatctttcgt
    12661 ccagttgtcg aaatatgttg gagccaataa atatatcaat tttcttaaag cccattcata
    12721 actatgcaaa tatggtagta atttttttga aaaaaataat gagtttgtat ctaaaatagt
    12781 agtgtaattt aaatgtgact tgctcgcttc aatattaatt tcatttagaa aaatttgaaa
    12841 tgaatgtaca tcggttatcc ctattttacc agccttatta tactgaaata ctacatgtaa
    12901 cgaatcatta taatttttaa tatcaaaact aaattcgtat ttttttccgt tattttgata
    12961 ttctaaaagg ttgtcttgta tatatcgtga taatacttcc aaaaaaactt ctttaatatc
    13021 atccattttg ccttgtttag ggtaatataa atattcaaca acttgcttgc taatatgtcc
    13081 tcgccttctt ttctttcaac gatttaaaat tttccaaata acttgataac tactaagtaa
    13141 gcctcaaaca acaaccacaa atgaattttt cactaatatt gatgattgtg atatttactg
    13201 gtttttattt tttatttctt tataatattg ttcttcttct cttaatatct ttttaacctc
    13261 cttttttatg ctagcataca tcgataaact attgtctgtt cgattgaaac aatgataatt
    13321 ctctccatca aagtcataaa aaaccacatc acttgatttt ccatctgaat tagttaactt
    13381 aaatttagta ttgagtagca attcattttt ttctttatcc atttccatca aaattggttt
    13441 aacttctttt aaatagttca aatatatttc agttgtaatc agattaaact ttgcaattgt
    13501 gtacacatat gagatacgtg gaaaatcctc aaatcgagca gatatatctt ctttaatttc
    13561 atctatttct gattttaatt tttcattaag atcaaaatga ggcattgtta gaatttcatc
    13621 caaatcaaag tatactcttt gttgttcaat atttaccggt aagtgaccat gctgagaata
    13681 atttctaaca tgtaataaaa atctgtacga gaaatgttca tcataaggct tactcagaat
    13741 tttattctta aaagatttaa aatctttttc tgctaaaaag tttttcatac aaacttcaat
    13801 ggattcagtc aaagttttgg ctgaactaat taagtttatc gtcaaagcat ttatctgata
    13861 ataatactgg tcttccgtta atttttcacc tgtactttca attaaatcat tagtaaaaat
    13921 tgtgaagtgt ttgagcaaat tagttaaatt atatctaaac acattaaaaa gtttatccaa
    13981 ctctataata tgacgtgtta attctacata atttaaaaat attcttttat cagattctgt
    14041 tattgtttct aataatgaat caatctgcct tattagctcg tcatcttgta aattactgac
    14101 gaaaaaccta ctatcacttc tcataattat attctcctaa tatgattttt tcaaaataat
    14161 caatatgtaa catagaagta tactctattg ttacatacct tatttcttat tatatcagta
    14221 tttctctgtg acacataagg gtgtaacata attattttaa acgaaatgac tacaagtagt
    14281 cattgaagca aatctccata agacatttgt aaaatctttt aaaaagaagc gtcgaaagaa
    14341 ggaacttttc ttcaacgctt cttttattga ctcaattttc aatattactt gaacgaataa
    14401 tctgatttct aaactctcga aaaacttctt gtggttgata atagtctgga tctatttcaa
    14461 atgtttctga gaataattca ttgaattttt ctactgaaat aatgatttta ccattcttct
    14521 ctcgactgtt ttctattatt tctgcttcta attcaaataa atctagtgac gaactaaaat
    14581 cataaatcat gtcatattga ataaaaaaat caagaaaaag ttgctcaaac tctttcttat
    14641 ttattactag tgtttcaagc ggatcaactt tattttcttc agccactctt ccaatttcct
    14701 cactttcatt ttcaaaaatc acaaaaatga tattaactta aaagccacta acaaaataag
    14761 acttacaaag taaagggtaa tccaacaaaa taaccattcg ctctacgtac tacgatttgg
    14821 tagtcctgcc tttcaatcgg taattcataa tagtaattta ctgtttcttc tttgccactt
    14881 tcaatatact ctggattatc caatatcata gcatactcat aaagttcttc accatcctt
//
LOCUS       DAIGUC010000063        14171 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.063, whole genome shotgun sequence.
ACCESSION   DAIGUC010000063 DAIGUC010000000
VERSION     DAIGUC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.063"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..134
                     /locus_tag="NOB46_002298"
     CDS             <1..134
                     /locus_tag="NOB46_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1059212.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(145..555)
                     /locus_tag="NOB46_002299"
                     /pseudo
     CDS             complement(145..555)
                     /locus_tag="NOB46_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(658..1953)
                     /locus_tag="NOB46_002300"
     CDS             complement(658..1953)
                     /locus_tag="NOB46_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1059213.1"
                     /translation="MNDSIKKMLRLIDKNLMITGVSYETFQKEKTLIVDAILSPAPCA
                     CSNCGSTVVDGTGKTIVVKNGKKETIVRFEQYNHMPMVMRLKKQRYTCKNCRTHWTAQ
                     SYFVRPRHSIANHVRYKITSLLTEKVSLSFIAKSCQVSLTTVIRILKEFKSYLPKSSK
                     RILPKVLMVDEFRSHASIEDKMSFICADGETGKLIDILPTRKLPRLTSYFLSCTNPEE
                     VEFLITDMNAAYFQLTKRVLPNAKVVIDRFHIVKHINQAFNDLRIREMNELRKAGKKR
                     QAEKLKKNWRFLLKKRSNINHYEYKTWKSFRAPKYPFFTEAMMIDRLLGFSTPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLEELPETLDDAFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVK"
     gene            2134..2444
                     /locus_tag="NOB46_002301"
                     /pseudo
     CDS             2134..2444
                     /locus_tag="NOB46_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009559264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
     gene            2952..4244
                     /locus_tag="NOB46_002302"
     CDS             2952..4244
                     /locus_tag="NOB46_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCI1059214.1"
                     /translation="MDGITIPWYAAIIGLIFAVFLILKKMNPVYSLFLGAIIGCLIGG
                     ASLSNTVDILVTGTQSIMGTAIRVLAAGMLAGVMMESGAAESIAHAIVNKLGSNKAIF
                     SLALSTMIITAVGVFIPVAVLIVAPIALSVGKQTGISKLALLTALSGGGKAGNIISPN
                     PNTIAAANGFKLDLSNVMIAGFIPAIFGLATAVLIASLIKKKGGKVKDSDIQEKSEKE
                     LLPLRKALIAPVLSIVLLLINPIGTMLHIQVLADLKIDAMYILPFASIVGTIAMGQAS
                     QIREYSKSGIYRVTDTVLILIGAGAIAGLISVSDLSKQVVHLISITGISGTLLAPISG
                     ILMGLAVGSTSTAVILATGSFGHAILETGTNSLAAAVMVHTGATVIDSVPQGNYFHIT
                     ANSMNMSIKERMKVIPYEICVGGVMTIVATILYGFILK"
     gene            4379..5524
                     /locus_tag="NOB46_002303"
     CDS             4379..5524
                     /locus_tag="NOB46_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI1059215.1"
                     /translation="MEKTFVLAPDSFKESMSAKNACEAMERGIRKVFPESKVIQVPMA
                     DGGEGTVDALVDGINGTKIEVMVSGPIPSEKIKAYYGLLADESTAVIEMAEANGIELL
                     AENKRNPLLTSTYGTGEMIKDALDKGVKKIIIGIGGSVTNDGGAGMAQALGVQFLDKN
                     DKELPVGGGALSELAKVDVSTIDPRLKETEVVIASDVTNPLTGPNGASFVFGPQKGAT
                     PDMVKKLDENLVHYAAVIQKNLGIDIKDQPGSGAAGGLGAGLLVFTGAKMESGVDLVI
                     QLTHLEEKIVQADYVFTGEGGMDFQTKFGKAPYGVAKIAKRYDKPVFACAGYIGEQVD
                     VLYEEGMTAIFGILDQAGPLKQALQAGESNLERTVENIVRVLNVCGG"
     gene            5594..6607
                     /locus_tag="NOB46_002304"
     CDS             5594..6607
                     /locus_tag="NOB46_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059216.1"
                     /translation="MSNLLTKEQANMIVSKLMADIPYNINIMNEQGFIIASGKEYRIG
                     ERHRGAERAIKQGEMVEIFKDTSLEKRGTNEPIILNGELLGVVGISGDPEEVRPFTKL
                     VKSIVLLLVEELNEFRKKEKKNQLKADFLKELLSIKDCYSEEMVHQALDDYGINLLRT
                     NRCIGSLEQETLRSCFPLHEVFEWYGMYIVFIDGNTIIDDDLSGLIVSSEQWNLGQGM
                     NEVDNTFLYLKFFQIPINKVFFSEDLYFIHLFDFSIKLDKNLLKKVESIYDEYYETLI
                     YFSSNNGNVKEVSEKLHIHRNTLNYRIQRIQELTRKDPKNWSHLWILMYHLAYCFKVK
                     FRT"
     gene            6999..8198
                     /locus_tag="NOB46_002305"
     CDS             6999..8198
                     /locus_tag="NOB46_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1059217.1"
                     /translation="MRDQTSGKMIRFYYTSLQFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFISQVIIKKRKIPLITVLKTMTAGLGVILLAGVLLPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVVFFVILHLLPDVKNQEVFPMTKEQDRPVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSIASISFAVRGFMMLLAGSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTSFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8693..9451)
                     /locus_tag="NOB46_002306"
     CDS             complement(8693..9451)
                     /locus_tag="NOB46_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1059218.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLF
                     KDDIVIFVSLNGETKELITAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            9619..10554
                     /gene="pfkB"
                     /locus_tag="NOB46_002307"
     CDS             9619..10554
                     /gene="pfkB"
                     /locus_tag="NOB46_002307"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI1059219.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            10551..11996
                     /locus_tag="NOB46_002308"
     CDS             10551..11996
                     /locus_tag="NOB46_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1059220.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSIIAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAVLFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAATVEMKEETNN"
     gene            12024..12479
                     /locus_tag="NOB46_002309"
     CDS             12024..12479
                     /locus_tag="NOB46_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1059221.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            12498..13472
                     /gene="lacD"
                     /locus_tag="NOB46_002310"
     CDS             12498..13472
                     /gene="lacD"
                     /locus_tag="NOB46_002310"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI1059222.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNQSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(13582..14067)
                     /locus_tag="NOB46_002311"
                     /pseudo
     CDS             complement(13582..14067)
                     /locus_tag="NOB46_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
BASE COUNT         4434 a         2288 c         2987 g         4462 t
ORIGIN      
        1 aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc atattatatt ggacatggtt tggggcgtgt agtgatgccc
      181 atacattttc tcaatcaagt ctgcgatttc cgacatggta ataccttttc ggaagaggtg
      241 aatgacggtc tcatctaacg tgtcattcgt ccgtctataa gcaggaacag tctgttgctt
      301 gaactcgcca ttgcggtcgc gcggaatctg gagatgaagt tccccatact cggtcttgac
      361 cgtacggtca taggagccgt tacgagaatt acccgtgtta aaaccaatgc gatcatactt
      421 ttcgtaatcg aggaaagccg ttaactccgt tttgagaagc gtattgactg ctttctccaa
      481 atggacacgg aataattcat tcaaatcgcc tttgttcgct agagtcttta gaatttctgt
      541 agtaaaatcg ttcataggga agtcctctct tctgggctct ttgtcaataa ggactgatga
      601 agctgtgcaa aatcaaatct gggtcaggat gaacctcatt ctggctcaga ttttttgtta
      661 tttcactttg attaattgat tgatcaaaaa gattctaatt ctcatgttct caaatgattt
      721 aaatccgtag gatactcgtt tcattgtctt tatatgggta ttctttgctt ctatttttcc
      781 attagaataa ggatagatca tcgcattggt gatgccttct tcataggtca gaagattttg
      841 aagtttctca cgaaaggcat catctaacgt ttcaggaagt tcttccaata aagagaaaaa
      901 taagtcaggg tctttgtctc gaaaggcttc tactaactca tgaaaaaagg gatacgcctc
      961 cttcaggggc gtggagaaac caagcaatcg gtcaatcatc atcgcttcag taaaaaatgg
     1021 gtatttaggc gctcggaaac ttttccatgt tttgtattca taatggttaa tgtttgaacg
     1081 tttttttaac agaaagcgcc agttcttttt caacttttca gcctgccttt ttttacctgc
     1141 cttacgcagc tcattcattt cacggatacg taaatcgttg aatgcctgat ttatatgttt
     1201 gacaatatga aatcgatcaa tcactacttt cgcatttgga agaacacgtt tggtgagctg
     1261 gaaataggcg gcgttcatat ctgtgattaa aaattctact tcttctggat tggtgcaact
     1321 taagaaatag cttgttaatc gaggtaattt acgcgtaggc aagatatcaa ttaatttacc
     1381 tgtttcgcca tctgcgcaaa taaagctcat tttatcttct atagaagcgt gcgaacgaaa
     1441 ctcatcaacc atcaatactt ttgggagaat cctcttagag gactttggta aatagctttt
     1501 aaactctttc aatatacgaa taacggtggt caaagatacc tgacaacttt tcgcaataaa
     1561 agataaagac actttttcag tcagtaaaga agtaatttta tatctgacat gattcgcaat
     1621 ggaatgtctg gggcggacaa aataactttg agcagtccaa tgggttcgac agtttttaca
     1681 ggtatagcgc tgctttttta agcgcataac cattggcata tgattgtatt gttcaaagcg
     1741 gacaatggtt tccttcttgc cgtttttcac cacaattgtt ttcccagttc catctaccac
     1801 agtagaacca caattgctac aggcacaagg agcaggtgag agaatggcat cgacaatcag
     1861 agtcttttcc ttctgaaagg tctcataaga gacccctgta atcatcaaat ttttatctat
     1921 taatctcagc atttttttga tagaatcatt catatagcat atcgtcctct cagtggttta
     1981 ttttgtcgtg atttaatcat actagagaac gatatgtttt ttaatatcta aaatgaaaat
     2041 gagactgaag aatcaattct gattcatcag tctcataaat tatagagcca caaaactctg
     2101 tggtcttttt ttgtagtaaa ggaggaattt ggagtggcca aactagatga agaatttgct
     2161 tttttggtat tgtcgatcat atcggagatt cccaaaggca aagtagctac ctatggacaa
     2221 attgccgagt tggcaggata tcctcgcaat tcccgtttag tcggtaaagt attgagccac
     2281 gccgaatatt atggtcgcta tccttgtcaa cgagtagtga atagtcaggg agaatgtgcg
     2341 aaaggttggc cggaacagcc gttactattg caagagaggg tattattttt cgcgagaatg
     2401 gacgagtgga tctgaaacgc tgccattggg atggagaaga gtgatctgta aaggatcatt
     2461 cactttaagc aatacagata tgatgaaata aaatatctat gaattttttt gcgttgcaat
     2521 ggagagattc tttgggagtt tgattctaaa ataaatcata tacaatgggt tatttagtgc
     2581 ccgattttgt taggagtata ggcaaaaaga attagtagtg aaaatcagta ttgtatttgg
     2641 gatatattct tttatttaat atgagttagg tccttagaac taaaagaatt aagagattga
     2701 ttgactttgt aaatagtaaa atacctaata agtatcaatg agttcccaaa tcgtatctag
     2761 ttgaatagaa gaaatttcta ttgaatacta tgtgattcta tgaatttatt taagttgtct
     2821 aaaatagtga aattctgaat ttatattatc gatatgtgca aatgaacaaa taacattgta
     2881 aatataccaa ttttatttat gaaataaagc attaaaatga aaacgtaaac aattaagaaa
     2941 ggatgtttga aatggatgga attacaatac cgtggtatgc ggcgattatt ggtttgattt
     3001 ttgcagtttt tttgattttg aaaaaaatga atccggttta ttcattattt ttaggagcaa
     3061 ttatcggatg tttgatcggc ggagcatcac taagcaatac cgtggatata ttagttacag
     3121 gaacacaaag tattatgggg acagcaattc gtgtgttggc agcagggatg ttggcaggag
     3181 tgatgatgga gtcaggcgca gcagaatcca tcgcccatgc aatcgttaat aaacttggaa
     3241 gtaataaagc aatcttttca ctagctctgt caacaatgat cattacagct gtgggcgtat
     3301 ttattcctgt cgcagtattg atcgtagcgc cgatcgcttt gtcagtcgga aagcagacag
     3361 gtatcagtaa attagcattg ttgacagcat tgtctggtgg cggcaaagct ggaaatatca
     3421 tttcgcctaa tcccaatact atcgcagctg ctaatgggtt taaattagat ttaagcaatg
     3481 taatgattgc tggatttatt ccggcaattt ttggattagc aacagcagtt cttattgcta
     3541 gtttgattaa gaaaaaaggc ggtaaggtta aagatagcga tattcaagaa aaatcggaaa
     3601 aagaattgct tccattacgc aaagctttaa ttgcacccgt tttgtcaatc gttttattat
     3661 tgataaatcc aattggaacg atgcttcata ttcaggtgtt ggctgatttg aagatcgatg
     3721 cgatgtacat tttacctttc gcttcgatag tggggacgat cgcaatggga caagctagtc
     3781 aaatcagaga atattcaaaa tcggggattt atcgtgtgac agataccgtt ttgatcttga
     3841 ttggtgctgg tgctatagct ggtctgatct cagtttctga tttatcaaaa caagttgtcc
     3901 atttgatttc cattacaggg atttcgggta cattattagc gcccatctca ggtattttaa
     3961 tgggcttagc agtaggatca acttctacag cagtaatttt agcgactgga tcttttgggc
     4021 atgctattct tgaaaccgga accaattcgt tagcagcagc tgtaatggtt catacaggtg
     4081 caacggtgat tgatagtgta cctcaaggaa actatttcca cattacggct aacagtatga
     4141 atatgtctat caaagaacgg atgaaagtga ttccttacga aatctgtgtc ggtggtgtga
     4201 tgacgatcgt tgcaacgata ttatatggat ttattttaaa ataaaattgt agagatagcg
     4261 ttttgtcaaa tcttttacaa aaatatgaac ttgaaaaaat atttattgaa aataacaatg
     4321 aagaaggtaa attctgtttg aaaagaagat tttcagcaga attttgagga gaagaacaat
     4381 ggagaaaact tttgtattag caccagattc atttaaagaa agtatgagtg ctaaaaatgc
     4441 ttgtgaagca atggaacgag gaattcgcaa agtatttcct gaatctaaag tgatccaagt
     4501 ccctatggca gatggaggag aaggaactgt tgacgcacta gttgacggta ttaacgggac
     4561 aaaaatcgaa gtgatggtgt ctggaccaat tccatcagaa aaaatcaagg cttattacgg
     4621 gttgttagca gatgaaagta cggcagtgat tgaaatggct gaagccaatg gtattgaact
     4681 attggcagaa aacaagcgaa accctctttt gacctctact tacgggactg gagagatgat
     4741 caaagatgcc ttggataaag gagtaaaaaa aataatcatc ggtataggag gcagcgtcac
     4801 gaatgatggc ggtgcaggta tggctcaagc gttaggagtg caatttttag acaaaaatga
     4861 caaggaacta ccggttggag gcggcgcgtt gtcagaatta gctaaagtcg acgttagcac
     4921 tatcgatcca agactaaaag aaacagaagt cgttatcgct agcgatgtaa ccaatccgtt
     4981 gacgggtcca aatggcgcat catttgtttt tggtccgcaa aaaggagcta cgcctgatat
     5041 ggttaagaaa ttagatgaaa atttggttca ctacgctgcg gttattcaaa aaaatttggg
     5101 gatagatatc aaggatcagc ccggttctgg tgcagcaggg ggattaggag ccggactatt
     5161 agtttttact ggcgcaaaaa tggaatccgg tgtcgatttg gttatccagt taacacattt
     5221 ggaagaaaag attgtacaag ctgattacgt gtttaccggt gaaggcggta tggattttca
     5281 gacaaaattt gggaaagctc catacggtgt agcaaagatc gccaaacgat atgacaagcc
     5341 tgtttttgct tgtgccggtt atatcggcga acaggttgat gttttatacg aggaaggaat
     5401 gactgcgatt ttcggcatct tagaccaggc cggtccattg aagcaagcat tacaagccgg
     5461 cgaatccaat ttagagcgta cagttgaaaa tatcgtccgt gttttaaatg tttgtggagg
     5521 ttaaaagttg tgttatctat caaaaaaaga ttaaactaac tgtataacca gataattctt
     5581 aggacggtaa tcaatgagta atttattaac aaaagagcag gccaatatga tcgtaagcaa
     5641 gctgatggcg gatattcctt acaatattaa tattatgaat gaacaaggtt ttattattgc
     5701 aagcggtaaa gaatatcgta tcggtgaacg acatcgtggt gcagaaagag caattaaaca
     5761 aggcgaaatg gttgagatct tcaaggatac ttccctagaa aaaagaggaa ccaacgaacc
     5821 aatcatttta aatggcgaat tattgggagt agttggaatc tcaggagacc cagaagaagt
     5881 ccgcccgttt actaagctag taaaatcaat cgtactgctt ttagttgaag aactaaatga
     5941 atttcgaaaa aaggaaaaga aaaatcagct taaagctgat tttttaaagg agctcctttc
     6001 aatcaaagat tgctacagtg aagagatggt tcaccaggca ttagatgatt acgggataaa
     6061 tcttctgcga acgaatcgct gtattggatc attggaacaa gaaactttac gtagttgctt
     6121 tcccttacat gaggtttttg aatggtatgg aatgtatata gtttttattg atggcaatac
     6181 cataattgat gacgacctct caggtttaat cgttagctct gaacaatgga atttaggaca
     6241 gggaatgaat gaagtagata atacttttct gtatttgaaa tttttccaga ttccaatcaa
     6301 taaagtcttt tttagtgaag atttatattt tattcactta tttgattttt caattaaact
     6361 agataagaat ctattaaaaa aagttgaatc aatctatgat gaatattatg aaacactgat
     6421 ttatttttct agtaataatg gaaatgtgaa agaagtgtca gaaaaactgc atatccatcg
     6481 taatacacta aattatcgaa ttcagcgtat tcaagaatta actagaaaag atcctaaaaa
     6541 ttggtctcat ttgtggatat taatgtacca tcttgcttat tgtttcaaag tgaagttcag
     6601 aacgtaagaa ataagaatat gtatccataa taaatgtttg gatttacctt atagatataa
     6661 aaagaaacaa atcattctgc aggaatcgat tactcgattc ctgctttttt tacttccttt
     6721 gcagcaaaaa agtgctcgta atctaagcga tgttggatag tttttagaat atatatattt
     6781 tcttcaattc cagaaaaaaa tgaccaagct agtatgctaa aaaagtacga tgcttctatg
     6841 atcttttttc cgtctttatt aacagatgtt ttaattgatc aacgcatatt gtaatctacc
     6901 ctaatttcca tagttcttca ccacttttaa aaatagtaaa acccctacaa gtatgctata
     6961 gtaaattgct aaagaaaaac caataaggtg ggagatgtat gcgcgatcaa acaagtggaa
     7021 aaatgattcg tttttattat acaagtttgc aatttctcta ttggatgatg ttttgttcgg
     7081 tctatgggtt tgcgacattg tttttgattt atttcaagat tgatccagct aaaatcggag
     7141 ggatcttagc attggtcaat attgtttcaa cggtgcttca gccttttatc agtcaggtga
     7201 tcatcaagaa aagaaagatt ccactgatca ccgtgctaaa gacgatgaca gcaggattag
     7261 gagtgattct cttagctggg gtattgcttc cgaatttgcc gatcattact tatatcttgg
     7321 gtgggatttt agtagtttcc atgcaatcat ttctcaatgc gctggcattt gagtattcaa
     7381 ataccggcta caggatcaac tttggttttt caagagctgg cggttcattt tcttatgctg
     7441 taacttcttt tttactggga cagttgttag cgatttattc tgccgcgatt ttgccgatct
     7501 tggttatagt tgaagcagta gtgtttttcg ttattttgca tctgctgccg gatgtaaaaa
     7561 atcaagaagt ttttcctatg acaaaagaac aggatcgccc agtttctttg agaaaaaaat
     7621 atcctttcct gattttgttg tttttaggtt tcagttttct ttttactttc cacaccatga
     7681 tcaacagttt tttggcacag atctttgaaa acatccacgg tggcagtaaa gaagtcggca
     7741 tcgcattgat gatcgccgct ttatgcgaat taccgggaat gatctttttt gaacagcttg
     7801 tcaaaaagaa atccagcaaa ttttggctgt ctattgccag tatttcattt gctgtcagag
     7861 gattcatgat gctgctggcc ggttcgatct tgatgatgga aatgacgcat ctcctgcaag
     7921 cctttagttt tgctttgttt attccagctt cagcttattt attcaatcaa tttctggcgg
     7981 atgacgaccg tgtatttgga caaacgatga tcattatcgc cacaactctt ggtggggtga
     8041 taggaaatgt cttgggcggc agtctgctgc agcatttcgg tgtatgggag atgctgattt
     8101 tcggtactag ttttgcggtg ctaggtgctt tattaactat tttgggcatt cgaaaaatac
     8161 cgaagacagg aaacgatagt gattctcttg ttgagtagca taaaaatact tagatactag
     8221 ttttatataa ataacatata gtgattattg gtgtaattac aaaaaacgag aataacttaa
     8281 gtaagcattt ctaaataatt gagaaacctc atctaaaaag ataagaaaat atccctaata
     8341 aaacttctgt aacattttag ataactgatt gtaagctgaa taataaacta taaggagaca
     8401 gttagacggt ctcctttttt tgcgtattat aattctagaa ttgttggaaa ttgataataa
     8461 ttaacaagaa atattagaca ggaacttcga actgcttatc acattcttat tattatatat
     8521 ttgcgtaagt agtcctggta gtctcaatgc actattctat cttgaaacta agaagttata
     8581 gaaggagcaa tgatagaaag cacgagaata caaatagcga ttaaatattt ttctagacaa
     8641 ccttagttaa ttcacacaga tatattttag gtacagtctt acagatatag agttagtgct
     8701 gtgtgaatcc tgatgttcgc agtgcatagg agtcaagtaa gattctagcc agtatagaaa
     8761 gtggaagtct ggagcgtacc tcataatctg ggaagaagga gccttctgat ttaaagccaa
     8821 caaaaggaat ctcgatatgt tccatcaaac ttgaatgacg attagcagta agcaaaattg
     8881 tcccgatctc agctttataa cagttttcag ctgcggtaat caattccttt gtttcaccgt
     8941 ttagtgaaac aaagatcacg atgtcatctt tgaataattt tctactaatg ttttttatga
     9001 tattgggatc agtatgcatc tcacaatatt taccggtaag ttgaaatttg accatcattt
     9061 cctgagcaat caattctgaa aaacctcggg caaaaatcat gattcttcta gcagccttga
     9121 ttcgttgaat agcatcttca atattcccgc tttctaccat attgatggtg cggattacct
     9181 cttgctcatt tttaagaata gcagtcttta ttccttcatc aactttatca agagcggcaa
     9241 aattgatatt tgtattttct ttttctttta acgaatgttt aaaagacgta aacccctcat
     9301 atcctttttt cttcatagta cgaacgacgg ttgctgttga aacgttggca tattcactta
     9361 gttttacaat ggaataggag gggatttcga gtatgtgact ttgaataaaa tcccagagat
     9421 atttctccga ttcacttaat tttgtatcca tattttgcct ccgattagtt aggataattc
     9481 tattgtaaag cgggagtttc ctttacttca agtttattta atatattttg taaaagtttt
     9541 caatgaattt agtcatttat gaaaacattt acattcgatc ttgatacata atgaatatgt
     9601 aagaaaggag gagcgtaaat gtcagtttat acatgtactt taaacttggc aatcgacctt
     9661 tttatcgaaa cagatgaaat gaaaccatcc caagtcaatc gaacaaacga tgatgatata
     9721 caagctaatg gaaaaggggt gaatgtttca ttgatcatga agcaattagg tatcgatagt
     9781 acagctttag gatttaaagc aggttttacc gggaattata ttgaggatta tttgcatcaa
     9841 aaagatatta gcactgattt tattagcgta ccgggaatga ctagaatcaa cgtttttaca
     9901 caagttaata aaaccaatga agaattcaaa ttggttaata aaggacctga gattcctcag
     9961 gaacaaatca aaacttttct aaatcaaata caaaagctgc aagctgacga ttatttgtgt
    10021 gtttctggca gtttgccgcg aggggtctca cccgaaattc ttattgatat cagtcgtatt
    10081 tgttttgaaa ataaggtcca tctgattatt gattcaagct atccggaaat aattgattgt
    10141 ctgccgtatc agccgttctt attaaaacca aacgaggagg aattgcaatc ttggtataat
    10201 gtcgagctta gtgatcgtga aggatatatt cattatgctg aacgcttgat tgccgatgga
    10261 gcgaaaaatg ttctcctttc tctaggagga gagggaggaa tatttttaaa taaggatatc
    10321 gtttattctg ggaattctcc taaaggtaaa gtagtcaata cagcgtgtgc tggtgacact
    10381 ttgttgggaa catttcttgc aggatattta aaaggtgaac aggtagatat taatttgaag
    10441 aaaagtttag cagctggaag ttcaaccgct tttcgtaaag gattaacaga tttttcggat
    10501 gttgcagagt tggaaaaaca aatcgaaatc aaagagggag cgagtaaaaa atgacaactt
    10561 acaaaattgt tgccgcaaca ggatgtccaa caggaattgc ccacacttat atggctcaag
    10621 aagcattgga gcaggcagct aagcgcaaag gggtatctat caaagttgaa acccatggtc
    10681 aagtagggat agagaatgaa ttaacaccag aagaaataaa aaacgctgac gctgtaatca
    10741 ttgcagctga caaagatgtt caagcagaac gtttcgcagg taagcgtgta atcgatgtgc
    10801 ctgtcagcaa ggggattaaa gatgctgacc aattgatcga agatgcgttg gctggtaaag
    10861 gttcaatcat tgcagaaaac aaaacagttg acgctgctgg tgagaaagcg gagatggggg
    10921 ttgcagcagg cattggtcac agtatttata aaaatctcat gaacggtgtt tctcatatgc
    10981 tgccgtttgt agtggcaggt ggggtaatta ttgcaatttc gtttgccatc tggggtgtgt
    11041 actcttttga tcccaatgat cctacttaca atccgactgc cgctatgtta aagggtgttg
    11101 gtgatgcggc aatgggaatg atggttccta ttttagcagc ttatatcgct gaaggaatcg
    11161 ctaaacgtcc tggtttggtt gttgggtttg ttggcggact gttagccaat tctggcggag
    11221 ccggtttctt aggcggaatt tttgcaggtt tcttagcagg ctactttatc ttactattgc
    11281 aaaaggtcat gaaaggcttg cctaaacaat tggatggtct gaaggcgatc ttcttatatc
    11341 cggtgatcgg tgtcttgttt gttggtgtag tcatgtcttt attagcaaat ccaatggaag
    11401 cagtcaacca aggaatgatg aatttcttgg caggattcca aaattctaat ccattaattt
    11461 tagggattat cgttggctgt atgtcagcat ttgatatggg aggtccagtc aataaagcgg
    11521 cttatgttac agggactgcg ttgttggcac aaggtaacca tacatttatg gcaggggttt
    11581 cggcagcttg tatcgcgccc ccattgatta ctggatttgc cgtactgttt tttggaaaat
    11641 atttcgacac gaatgatcgc aacgctggtt tagtcaactt tatcttgggc tcaacgcaca
    11701 ttaccgaagg agcaattcca tttgcggcta aagatccgct gcgtgttctg ccaactatga
    11761 tgctaggttc atcaattgct gctgtactga catatatgtt tggtgtccaa gttcccgcac
    11821 ctcatggagg ttttctagta ttacctgttg ttactggtaa ggttgcatgg gtagggtcga
    11881 ttttacttgg ttcaatcgtt ggcggagtaa ttttagggtt gatccaaaaa cgtagtgtag
    11941 aaaaacgtga agcagaagca gctactgttg aaatgaaaga agaaaccaac aactaaaggt
    12001 tattctagaa agaaggattt caaatgactt tgatcaaaac aaataaagtt tttatgaata
    12061 aaaattttac gacgcaagat gaggtaatga acttccttgc agatcagtca attgtcttga
    12121 gcattagtga agaccgagat gcagtttacg aaaaattgat ggaaagagaa gaagaaagca
    12181 cgactggtat gatggatggt tttgccatcc ctcatgccaa agatgctagt atcaaggatg
    12241 ccgatattgt gattgttcgg ttaaacggta aggtcgattg gaaaagttta gatggagaag
    12301 gaacggattt tgtaatcgct ctgtttattc cagattcaga ggctggaaca acccatctaa
    12361 aatttttatc tcaggtagcc agacttttga tgcacaaaga tgtgacagaa ggtctgaaac
    12421 aagcccagtc tgctgaagaa atagctgaac ttttaaacca aaaattagaa gaaaactaaa
    12481 aaggaagtag tgaaatcatg cctttaacag aaaaaaagaa aacttatatt cgtcaactaa
    12541 gtaatgaaag tggcatcatc agtgcgttag caatcgatca acgtggtgcc ttgaaaaaaa
    12601 tgatcggtaa atttcaaaat caatcagcaa ccgatgaaca aatcatcaat ttcaaaaaaa
    12661 tcatttcttc tgaattgact ccatatgctt cagcaatctt attagatcca gaatatgggt
    12721 tgccggcagc cgaagttcgc gataaaaatg ctggtctgtt gttggcctat gaaaaaactg
    12781 gttacgatgc ttcaactcca ggacgtttac cggatatttt atctatttgg tctgtaaaac
    12841 gtctaaagga gcaaggggcc gatgcttgta agttcttgtt atactacgat gtagatgaat
    12901 ctgatgatat caatgaccaa aagaaggcgt ttatggagcg gattggttct gaatgtgttg
    12961 ctgaagattt gccatttttc ttagaattgg tttcttatga tgccaacgat cctgatactt
    13021 cttcgaagga atatgccttg aaaaaaccgc ataaagtaaa tgaaatgatg aaggaatttt
    13081 ctaagcctcg ctatggagtt gacgttttga aagtggaagt tcctgttaat atgaactatg
    13141 tggatggtta cactaaaaat gaagttgctt ataccaaaga agaagctgct gcttatttca
    13201 aagaacaatc cgagactacc aacctgccat ttattttctt gagcgcagga gtaactgctg
    13261 aattgttcca agaaaccttg aaatttgcaa aagaggctgg ctctacattc aatggggtac
    13321 tctgtgggcg cgcaacttgg gcgaatggtg tagaaccatt cgttactaaa ggtgaatatg
    13381 ctgccaaaga atggatgcag acacaaggac gcaagaacat cgaagagctg aataatgttt
    13441 tgaaagaaac agcaacagct attaaattgt aagaaagctt taactataac cttaagtttg
    13501 taacctaatg atttttaata atcaatttga gcttttaaat aaagaattgg aagcgtcccg
    13561 acgcttcctt tttcgtttgt cttaaggcat gataggttct atgttgtcgt tcaataagcg
    13621 caagaaggtc agcatttttt tcttagagta tgcaaaattg ctttctaccc aatgatttaa
    13681 aacggagagg cacccttgga tatggtaaat ggtgaagtaa cgcatttctt ctgtgatcac
    13741 ggtttttttg tcttcttgta gccagatttt taaataattt tcttcgatca gattatttaa
    13801 tctcttttgg aattggatat ctccgtggtt gataacgaat aacttgtaca cgaacgtatt
    13861 tgtatagaca tagtcgatca aatgagcgta tagatcctcg tagctgtgtg tcgtgtcata
    13921 ggaaatgatt tcatccaagt cttagaaaaa gctattttct agcttttcat aaagatcata
    13981 gatatccgta taatgtttat aaaatgtcga acggtgaaga tcagcagttt cggtcagttc
    14041 acggatagtg atgttttgaa tttttcgcga attgtaaaat taagttagaa aaataaaaag
    14101 gcatttatgg tacactcaaa ttgtatttcc gacgaaagaa aacaaaggag tgtaaccata
    14161 aatgacctac a
//
LOCUS       DAIGUC010000064        14110 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.064, whole genome shotgun sequence.
ACCESSION   DAIGUC010000064 DAIGUC010000000
VERSION     DAIGUC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.064"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            268..2433
                     /gene="acm"
                     /locus_tag="NOB46_002312"
     CDS             268..2433
                     /gene="acm"
                     /locus_tag="NOB46_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HCI1059223.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2705..3190)
                     /locus_tag="NOB46_002313"
     CDS             complement(2705..3190)
                     /locus_tag="NOB46_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCI1059224.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3280..3625
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3670..4311
                     /locus_tag="NOB46_002314"
     CDS             3670..4311
                     /locus_tag="NOB46_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI1059225.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4330..4965
                     /locus_tag="NOB46_002315"
     CDS             4330..4965
                     /locus_tag="NOB46_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI1059226.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4983..5798
                     /locus_tag="NOB46_002316"
     CDS             4983..5798
                     /locus_tag="NOB46_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI1059227.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6117..7553
                     /locus_tag="NOB46_002317"
     CDS             6117..7553
                     /locus_tag="NOB46_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1059228.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7742..10189
                     /locus_tag="NOB46_002318"
     CDS             7742..10189
                     /locus_tag="NOB46_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI1059229.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10419..11486
                     /gene="rlmN"
                     /locus_tag="NOB46_002319"
     CDS             10419..11486
                     /gene="rlmN"
                     /locus_tag="NOB46_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI1059230.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11679..12782)
                     /locus_tag="NOB46_002320"
     CDS             complement(11679..12782)
                     /locus_tag="NOB46_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1059231.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13335..13883
                     /gene="aac(6')"
                     /locus_tag="NOB46_002321"
     CDS             13335..13883
                     /gene="aac(6')"
                     /locus_tag="NOB46_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI1059232.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4853 a         2319 c         2979 g         3959 t
ORIGIN      
        1 tttgtaagtt aaaaattgga aatatagatt gaaaaaatga aagcaataag taaaataaaa
       61 tgaatatatg cgaaaaaata atttacatta ggaaaaacct tgtaaaaaca gttttttggc
      121 atatttattt tttataaata tttgtaaaat aactatcaat tttttagtta aaagattgga
      181 aatgagtggg ggaggaattg aagaaaggat ttttgagaga tgatatagta ggttttattt
      241 ttagttaaaa taggggagat agaaaaaatg aaaaagtgta gaaatattat tttatcaatg
      301 ttatttatta ttactaatat aacatcactg attcctgttc atgtctatgc ggatgcaggc
      361 agagatatca gcagtaatgt cacttcgttg accgtggacc caacgaatat tacagatgga
      421 ggaaacataa aagtaaaatt ctcgtttgac gaaaaaaaac aaaatatcca accaggtgat
      481 tatctttgga tcaattggcc aagtgaagga aatattcgcg gtgaaggatt ccaaaaagaa
      541 atcccattaa tgattgaaaa taaaaatgtt ggaactttaa cggtcagaaa agattctgcg
      601 caggttgtgt ttaatgaaaa tattaaaaac ctagactcag tagaaggttg ggggcaattt
      661 gagatacagg ccagaaacgt aaccgatacc ggtgaagaaa atacgggacc attcaccgtg
      721 acgagcggtg ataaaacagc tactgtaaat gtgacaaagc cagcttctgg ttcttcttct
      781 agcgtttttt attataaaac aggagacatg ctacctgaag atactaagca cattcgatgg
      841 tttttgaata ttaacaataa cggcacttat gttgaacaac cagttaaaat cagtgatgaa
      901 atccaaagtg gacaaagatt agatccaagt acgtttgaaa ttaatcaaat acacttaggt
      961 gaacagaagg tttatagagg agaagaggga atccaacaat ttttacaaga tttccccagc
     1021 gctacattta atttttcagt aactgataat tacattgaaa taactatacc aaaaaacttt
     1081 gtcaatctta ggaaaataat ggtgagttat aagacgatca tagaaaaccc agaacaaata
     1141 aattttgaga atcattcgga agcttggttt aaagaattta ataaacctgc tgttgatgga
     1201 gaaagtttca atcatacagt taaaaatatt tcagcttctg gtggagtcaa cggtacagtt
     1261 agaggcgaat tgaagatttt caaatatatc aatgacacag agattggtat cccaaatgtg
     1321 actttcgaat taagacgagc agatgaacag cctattcaag gacagtctag tatcctgttg
     1381 acttcgaatg aacagggaga agctagtatc aaaggcctgc aagtaggaga ctatgttgta
     1441 aaagaaaaag aagcacccaa ttggattgat tttgatccac taagttcaaa tgaactcaaa
     1501 ttctccataa acgaaaatga tacagaggga gtcagtttac ctatttataa caagaaaaag
     1561 gttacgaaca tcacagcaac taaaatttgg aacggtggaa ccactccaag accgagtatt
     1621 tattttaaat tattcagagc aagtacaaac aattgggaac cagttcctga tgcagaaaca
     1681 aaacgattag acaatggaat aacttcagtg acttgggaag atatccaaca gtatgatgat
     1741 agtggaaacg aatatacgtt taaagtgcaa gaagtagatc aaaacggaaa tgattatgtc
     1801 ccttcaggtt atcaaaaaat tgaaaacggg ctagtcgtta caaatgagaa taaagaagtc
     1861 atttcagtct caggacaaaa aacatgggaa gacaatgaga accaagacgg caaacgaccg
     1921 acgacgatca cagtaaatct attagccgac ggtcaaccga tccaacacaa agaagtaagt
     1981 gaaaaagatg attggcgcta tcgtttcaca aatctgccaa aatacagaga cgggcaagaa
     2041 atcatctata ctgtaacgga agacaacgtg cccgaataca gtacgacgat tgacgggtat
     2101 aacatcaaaa acagttatac accggaaaaa acaaatatat ctataccagg tagccatata
     2161 acaccgtgga aaaattttcc agagaagaca gagagagaga aaattagaaa tctattctct
     2221 caaaaattgc aaatatttgc tcatacagga gaatccagcg aacaaagaag caattatatt
     2281 agtaagagag ctgtacctaa acagataaca aataaatcaa aaagcattct tcctaaaaca
     2341 agtagtaaaa aatctagttt tgctgtaatc attggtttat tgatagtaac tatctgtgct
     2401 gggatattct tacaaaaata taaaaaagtt tagttagaat ataatatttt ttgttaaata
     2461 tgactgaaat caaaagaata aaattccgat ttataatcga aaaaagaagc atttttatat
     2521 atgcttcttt tttcgtagaa tcaataaata tggatttggc taactatgga agaatactcg
     2581 tattagtttt cagcgttcat actagttgtt acattgtttg attggccaaa agaatttctg
     2641 atatattttg tgctaaataa agaaaaagac gcttgaattg ggaaataaga aaactactct
     2701 atcattacaa attttcataa actggcagat gttctaagta aacaagtatc ttttcaaagt
     2761 cggaaaaatc cataatcaac gtagtggtat tgatatttgg atgaaagcct acggtatctt
     2821 gacgatcaat agcagcatcg atcacgactt ggattttttt ctctttgtcg tgcatcaatg
     2881 ctaatggagt cactgtacct gctggaacgc ctaggaggtc aggaagctgt tcttcagaaa
     2941 caaaagataa gcgcttttct tttaattgtt cagctagttg ttttaaatcg gcgtgctttt
     3001 catcaggcaa gatgacaaga tagatttgtt ttccttttct tgatttcaat aatagatttt
     3061 ttacttgcgg accaggtagg gaaaaaggga catttttgac tgacgtaatc gcaggatgat
     3121 cgactttttg aaaagagata cccagttttt ttagtagttc ataagcttct tgttcggttg
     3181 cacgactcat cgcgcatcac cctccttttt ttattagtgt atcataaaaa agagttgaca
     3241 aatgaaaaat aatcatgtaa attacacgta aagttaaaac aaatgacatc gaaaagaaga
     3301 gtagccgtta ggtgttttta gagagtctct ggttggtgga aagaggcagc agttaaccgt
     3361 gaaacacatc ttggagtcga ttttctgaag cgtatagtag gaaaatccgg ggagcccgtt
     3421 acagctgcgg tcgttgctag atgaccagat aaggctggct tttccgtgag gagtcggtaa
     3481 aaaaaggtgg aaccacgtga ttaacgtcct ttgatcttcg gatcaaagga ctttttgttt
     3541 tcatctgaac ggcaacgact gtgtgaggtt ttttctgcaa ggaaaaaata aacagaggtg
     3601 gaaccacgta taatacgtcc tcttggcatt tgccaagagg atttttttat tttaaaggag
     3661 gaaaagaaga tggagtattt gattgaagtt atgccgcaat tattagtagg agcactcaca
     3721 acattgaaat tatttttatt taccttgatt ggctcattac cattagggat tgttttagca
     3781 ttaggattgt ctttgcattt taagccgcta cgctacttgc ttcaaacata tgtatgggtt
     3841 atgcggggaa caccgctgtt gttgcaactg atttttattt tttatgggtt gccgacgatt
     3901 gggatcgttt ttgatcgttt cgaagcagca ctcattgcct ttatcttaaa ctatgcagct
     3961 tattttgcag agatctttcg tggagggata caatcgattc ctcaaggtca atatgaagca
     4021 gcgcaagttt tgcaattaag tccctttcaa acggtgacga aaatcgtcat cccacaagtg
     4081 acaaagattg ttttaccttc tgtagggaat gaagttatca acttggtcaa agattcttcc
     4141 ttgatctata tattaggttt aggtgacgta atgcgtgctg ggaaaatcgc gatggaacgc
     4201 gacgcgactt tactgccttt gctaggcgtg gcaatcatct atcttacatt gactggtatt
     4261 ctaacaatcg taatgaaaca agttgaagga aaattaaatt attaccgcta actgatagga
     4321 ggaagaaata tgattgaatt gaagaaagtg aacaaagcat ttggtgaaaa aaaaataatc
     4381 aaagatttga atctaatcat tccagatggg aaaacattag ctatcgtagg tccttccggt
     4441 ggcggtaaaa ccacgctttt acgtatcttg gctggcttag aaagttctga cagcggagaa
     4501 ttttatttag acggtgtacc gttcaaccca ttcgagctta aaatgaaaga acaagttgta
     4561 ggagtcgtat tccaagactt ccagctattt ccacatctga atatttttga aaacattacc
     4621 ttagcaccaa aaatggtatt gaaacagaca aaagaagaat acaccaaaaa agcagaagaa
     4681 ttagcggctt cattagggat tagtgattta ttgaatatct atccttatca gctttctggc
     4741 ggacaaaaac agcgggtagc gattgccaga gcattggcta tgaatccacg ggtattggct
     4801 tatgatgaac caacaagtgc tttagatcct gaattacgcc agcaagtcga gcgtttgatc
     4861 ctatcattga aagaagatgg ggtaacccaa attattgtca cccatgattt agtatttgca
     4921 gaaaatgtcg gtgatcaatt actaaaagtt tccccaattc attaagaaag gagaagatag
     4981 agatgaaaaa aaccagtttt ctattcgctt tgatcgcagg tcttcttctt tttgcaggct
     5041 gttcgaacaa aaaaacttca gcagataatt gggcgactat caacgaagag aaaaaaatcg
     5101 ttataggttt agacgataca tttgttccta tgggatttag agataaagac gggaagctca
     5161 caggatttga tattgattta gccaaagcag tctttgaaca atatgggatt acggtagact
     5221 ttcagcccat tgactggtca atgaaggaat ttgaactgaa caatggaacg atcgatttga
     5281 tatggaacgg ctattccaaa acgccggcaa gagaaaagaa agtgcaattt acaaaacctt
     5341 atatggaaaa cgatcaagtg ctgatcacac ctaaagaatc aggaatcaca aactttggac
     5401 aaatgaataa taagagatta ggtgcgcaaa atgggtcatc tggttatgat gtatttacga
     5461 aacaaccaga agtattaaaa gagatagtca aaaaccaaga tgctgttttg tatgatagtt
     5521 ttaatgaagc attgatcgat ctgaaaagca gacgggtcga tggtctgctg atggataaag
     5581 tatacgcaga ctattatttg aaacaaagaa acgaactaga agacttcaac ataacaaaag
     5641 gttcttatga gagtgaggat tttgcagttg gtgcacgcaa gtcagatagt acattagtga
     5701 aaaaaatcaa tgaagcccta gatcaactag agaaaacagg tgaattccaa aaaatatccg
     5761 ataaatggtt tggcgaagat gttacgccga gaaattaaca aataggggac tgtgacaaaa
     5821 gacgtgtcac agtccctttt tccgaataaa cagtgttctc ctgccaactc cttgtgactc
     5881 ggagctgaat ggcaggctca caacctcttg gtaaacggtg ttcaaaagcc agtttttcgg
     5941 tattaagcca aatttatgca aaaatgtaga aagccatttt cacaaaattt ttcttactac
     6001 tcgaaactaa gcgacttttt cacaacctcc tttacataat tttattttgt tgtggaaggg
     6061 gtttcgtgtt attctaaaag aggaacgatt gaaggttata ggaaaggaag agatgaatgg
     6121 aacacaaaga acttacctca tttccaaaag attttctgtg gggctctgct tctgcagcgt
     6181 atcaagtaga aggagcttgg caagaagatg ggaaaggaga atcagtctgg gatcgatttg
     6241 tacggatacc tggaaagaca tttaaaggaa cgaacggtga tttggcagta gaccactatc
     6301 atcgttataa agaagatatt gctttaatga aagaacaagg tctgaaagct taccgcttct
     6361 ctgtagcttg gacacggatt tttcctaatg gacgaggaga agtcaatcaa gctgggctcg
     6421 ctttttatga gagattgatc gacgaattga ttgaaaacga tattgaacct atgttgactt
     6481 tatatcattg ggatcttcca caagcattgc aagatgaata taatggttgg gaatcacgtc
     6541 agatcattga agatttcact cattatgcag aaacattatt tgaggcattc cgcgggaaag
     6601 tccattactg gattagtttg aatgaacaaa atatcttcac ttcattaggt tatttgttag
     6661 cagcacatcc gccaggtgtg acagacccga aacgaatgta tgaagttaac catattgcta
     6721 atttagcaaa tgcatctgtc atcaataaat ttcacgagtt agaaatgcct ggaaaaatcg
     6781 gaccaagctt tgcgtatacg ccaaattatc caattgacag taatcctgaa aatgttctgg
     6841 ctgctgaaaa tgcagaagac ctgatggcca attattggat ggatgtctat atgtggggaa
     6901 aatatccgat tgctgccatg aggttcttag aagaaaaagg atgggcacca acgattgaag
     6961 ctggcgatgc agaattgcta gaatctgcta aaccagattt tcttgggatc aattactatc
     7021 aaacggcgac gaatgcattc aatccattaa acggagttgg tgctggaaaa atgaatacga
     7081 caggaaaaaa aggttcatca gaagaaactg gagttcctgg aatgtataaa aaagttgaga
     7141 atccatttgt cgaacgaaca aattgggact gggagattga cccagaagga ttaaggatcg
     7201 gactgcgtcg tatcacaagc cgttaccgca tgccggtact gattacggaa aatggcttag
     7261 gagagtatga caagttgaca gaagataaac aaatccatga cgactatcga atcaattact
     7321 tacaaagcca cgtcaaagcc atcaaagaag caatttcgga tggagcagaa gtcctaggct
     7381 attgcacctg gtcttataca gatttgctta gctggctgaa cggttatcaa aagcgatatg
     7441 gatttgtata tgttgatcaa gacgaaacac aagaaggatc tttggaacga tataagaaag
     7501 acagttatta ctggtaccaa aaactgattg aagaaaatgg agagaacctt tagttcacat
     7561 acttaaaaca agaaggtacg gctggatatg gccgtgcctt ttcttgataa aatcatttag
     7621 aaattaagaa aaactgtaaa ataagctgaa aaatgaaaga aagcgtcagt tctttcaaac
     7681 aaaactttag ttcccttact tttttttgta taatgaaact tgatgaaatg agggataata
     7741 aatggcacaa aagaaacggc ctactaaaaa aaggaaaaag acgaaaaaaa cgaaaaagca
     7801 aaaacagcag caggaacaaa tgctgacgat tggtgttggg tttgccttga ttttatttgc
     7861 tgtcttcggc tttttaaaat taggtttttt aggaatattg attgcaaacg gctttcggat
     7921 cattgcagga aatacttacc aaatcctctg tcttttatta gccgtattag gattttggat
     7981 tgtcattaag aatacagagt tttcaattgg taaaaaccga cgctggtttg gcggcatact
     8041 cttttatttc ggtatcttat tattgttaca tgcccattta tttggcaaac tccatactgg
     8101 ggaaccaaat atcatgggga cgacatggga tttgttagcc agtgatataa aacaaagtca
     8161 agtagacaat aacgttggtg gtgggatgat tggagcaatc ctttatcatt ttacttactt
     8221 cttgattgca cagcctggaa gttatttagc agcagtgcta ttactggcag gaggagcatt
     8281 cctgttcagt aatctggaag gctatcagct gttaaatggt atccaatcaa ttggagaacg
     8341 agtacaggaa ttattggaag gtgatcctgc caagcaagct cgaaagcaag cggcaaagga
     8401 agagagaatg aaacagcgcg cagaagcgaa agaagcaagg cgcttagctg caaaagaagc
     8461 tgcagaaaaa gaagctgcag aatatgagaa gaaaaaagcg gtgagccagc aaagggaaaa
     8521 tactgctgat gaatggcagg aaccagaaaa tacagagccg gagcagctaa gttttgttcc
     8581 aatcgacagt tttcaagaaa atatccatcc tgcgaatcta gagaaaccag taccagatac
     8641 accaaaacag accaatacag cagaaggttt ttcagatgag ttgccagagg atgacggtac
     8701 ctcattagaa tttgagattg aagcagaaca ggaaaatcaa gactatgaat taccgacagt
     8761 tgatttgctt gattctatac caactgtgga tcaaagtgat gagtataaaa aaattgaaaa
     8821 aaatatcggc gtattagaac aaactttcca aagtttcggt gtcgatgcca aggtcgtcaa
     8881 agccagctta ggaccatccg tcacaaaatt cgaagtccag ccggctgtag gggtaaaagt
     8941 aagtaaaatt gtgaacttaa cagatgatat cgcgcttgct ttagcggcga aagatgtccg
     9001 gatggaagca ccgattccag gtaaatcact gattggtatt gaagtaccaa atggaaagat
     9061 cagtatggtt tcctttagag aaatcatcga agcacaacca aaccacccag ataaattact
     9121 agaagtacct ttaggacgtg atgtttctgg acgggtacaa acggctgatc tttcgaagat
     9181 gcctcactta ctcgtggctg gttcgactgg tagtgggaag tcagtagcaa ttaatgggat
     9241 tatcacaagt atattaatgc gtgctaagcc ccatgaagta aaactgatga tgatcgatcc
     9301 gaaaatggtt gaattgaata tgtacaacgg catacctcat ctgttgacgc cggtcgtgac
     9361 gaaccctaga aaagcagcgc aagccttaca aaaagtagta caagaaatgg aagaacgata
     9421 tgaaaaattc gcggcaaccg gagtaagaaa tatttctggt tacaatgaat ttgttcaaca
     9481 gaaaaacttg gaaaacggaa cgaaacatcc aaccttacca ttcatcgtag tgatcgtaga
     9541 tgaattagct gatttgatga tggtagccag caatgaagtt gaagatgcga ttattcgttt
     9601 agcgcaaatg gctcgggcag cggggattca tatgatccta gctactcaac gtccaagtgt
     9661 ggatgttatc acaggaatca tcaaagcaaa tgtaccttcc agaatggcat ttgcggtatc
     9721 aagcggtaca gattctcgga cgatcattga ttctaatggg gcagaaaagc tcttagggcg
     9781 aggagatatg ctattcttgc caatgggtga gaataaaccg atccgtgtgc aaggagcatt
     9841 catttctgac cacgaagtag aacgggtcgt tcaatttgtt acagatcagc aagaagctca
     9901 ttatgaagag aaaatgatgc cgacagatga agttgaaacg acaggtgctc cagaacagcc
     9961 acaagatgag ctgtttgaag aagcaaaagc acttgtcgtt gaaatgcaaa cggcaagtat
    10021 ttcccttctc caaagaagat ttcggatcgg ttacaaccga gcagcacgtt tagtagatga
    10081 actggaagct catggagttg ttggcccgtc agaaggaagc aagcctcgga aagtattcat
    10141 tgagcaggaa gaaacatcag aaacgttgcc ggacgataat gacatgtaaa acttgtgtga
    10201 tgaagggttg aaaaacgaat aaccaataaa aagacaaggc atgatgatac caaaagaaaa
    10261 aatggttttt ttccatcttt tctaatacgg tatgatgtct tgtcttttta gtttttgtga
    10321 gattaaagtt ctattcgatt tatttgtgaa gtattgcatt aaggaaatga atcatgtata
    10381 gtatgtagcg aaactttgag aaaaagaggg aaaatacttt ggaaaaacag tccatttatg
    10441 gcttgacgaa tgaagaatta atcaattggt ttatagaaaa cggcgagaaa aaattccgag
    10501 ctgcccaagt ttgggaatgg ttgtatcaaa aacgtgtaag taatttcaca gaaatgacga
    10561 atctatcgaa acaattgatc gaaaaattat cggagcattt tatcatcaat cctctaaaac
    10621 agatggtcgt ccaagaagct tcggatggta cagtaaaata tttgtttgaa ctccctgata
    10681 aaaacatgat tgagactgta ctgatgagac aagaatatgg cttgtcagtt tgtgtgacga
    10741 cacaagtagg atgtaatatc ggctgtacgt tttgtgcaag cgggctgctc aaaaagaacc
    10801 gtgatctgac tgctggagaa attgttgcac agatcatgat ggtccaacat tattttgatg
    10861 agcgcaatct tggcgaacgc gtttcacatg tcgttgtaat ggggatcggt gagccatttg
    10921 ataattacga caatgtaatg gactttttgc atatcatcaa tgatgccaaa ggattggcaa
    10981 ttggtgctcg gcacattaca gtttccacta gtggattagc acacaaaatc aaggaattcg
    11041 ctaataacgg cttgcaagtc aatctggcta tttccttgca cgcgccgaat aatgaggtgc
    11101 gaacatcgat catgcggatc aaccgaagtt tcccaattga gaaattgatg gaagctgtgg
    11161 atgagtattt agagaaaaca aaccgtcgaa tcacgtttga atatatcatg ttgaatcaag
    11221 taaatgatag accagagcat gcgcaacaat tagcagatct attaaaagat aagaaaaaat
    11281 tagcatatgt caacttgatt ccatataatc cagtcagtga acatgatcaa tattctcgca
    11341 gtccaaaagc tgatgtattg agattttatg atgtattgaa gaaaaacggc gtaaactgtg
    11401 tgatacgtaa agaacatggt acagatattg atgcagcttg cggacaattg cgaagcaagc
    11461 aaatgaaaaa aacagttgcc aaataatcgt atcctactcg ttttttcaat taccataaaa
    11521 ggagcagttt tcttaattaa ggaactgttc aacttaaata agagaaaaga ttctatagcg
    11581 aaagctataa agcttttttt gacaagaaaa accctcatca agcaaagaaa tgtcctcaat
    11641 ttgatgacag cctgcttgat gggggtttta gcaattattt aactgatttt cttatatcct
    11701 tgctggcttt cttgtgtagc atgataagtt tctacgtcaa gaatggcctg tttaaatttt
    11761 tctcgggtga tttcataagg cacatgttta atatcatttg ttgccatggc tttatctaag
    11821 attgcttcta aatcggtcgt gacattgaga ttcatgtcgg ttaacgatac tggaagttgg
    11881 ttctttttca taaacacata gattttatca aacaaatcga actgctgatc catcatcaat
    11941 aaggtcagta caccataact gacagatgct ccgtgaaggt atccctccat tttttctaga
    12001 acagtcgtac cgtaatagaa tgagtgtgcc atagcagaat tatagttatt gttaactaaa
    12061 acagaaacca atccggtagt aacaatgata tccgaaacga cttgttcaat tgcatatgag
    12121 ggacgatcgt cggcactatc tttcaatgct tgcgtaccat aagtcaagag acgatcaatg
    12181 cacatttttc cgatttggat tcctaatcta tccgtgtagc ctagatcatc gccacgagca
    12241 gaaaaagtag attcgacttc tttggataaa gcatcgccaa tacctgccca taagtattta
    12301 tcaggtgctt cggcaataat tgctgtatca atgaaggtgt gtacaggtgg ttttgaagga
    12361 aagaagagtc cgtccattac gccttcttcg ttatagatga cacataccgc agtgacgggc
    12421 gaacagttcg aaccaatagt gggaaaggtg aagactggtt tagctagttt ttcaccaatg
    12481 acttttacag tatcgcaagc acggccacca ccgactgcaa acaggacgtc tgctttttgg
    12541 acactttcat gctggatcaa ctgttcaata tttccataag ttgaattacc cccgtaccag
    12601 agactggcga caacctctat ttcctgtgtc aaagctactt ttattttgtt ttctgccttt
    12661 gaaagtgcag tcttccctcc aatcagcact acttttgtcc catattcttt gacgattcca
    12721 tttgcttttt catacgcatc tgttccaatg gtataatttg gtaagaaaac actttgactc
    12781 atattcattt ccttctttct tcgttgaaac gggttaaaat tttaaagagt gatcgatctg
    12841 actgcggctg tagatggagt agaggtgaac ctaagacagg ataagtgatg aataaggtgg
    12901 catgaacacc ttgaaatcat caataagtat cctaaaaacg aacaagtaca aaaacattga
    12961 aaacgacaat aatgaatttt tgttcctctt agtatttcta ccgattccct ttgctttttt
    13021 gtaattatct aaaaattcta aaaattaaga ttattatatg aaaacaggtt ttatttgtca
    13081 attcataatt ggtttttttt aaagcaaaag ataatctata tcatgatgaa caaacagagt
    13141 tttttcctcc aattgatggc tttcctgatc tttcctattt tgaataaagt gtttctgtat
    13201 aattttttta ttttataagt aagataaata atgaaagaat agagatactg attggtagct
    13261 aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat aagcaagaac
    13321 aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta ttgaaagatc
    13381 agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc tcggcagaag
    13441 aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac caagatgagt
    13501 tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa ttgcatccat
    13561 tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc aattacttag
    13621 aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat gatttagacc
    13681 atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa gtggcttcca
    13741 tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat aaaatcgtag
    13801 gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca aaaacgatta
    13861 ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc agcttcaaga
    13921 aataagaagg aatttacgaa aattacttct tgaatttttg tgaaattcca acttatttcc
    13981 gaagaagcta cttttggaac accgtgtacc agaggttgtg aaaaagtcgc ttagtttcga
    14041 gtagtaagaa aaattttgtg aaaatggctt tctacatttt tgcataaatt tggcttaata
    14101 ccgagaaact
//
LOCUS       DAIGUC010000065        13948 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.066, whole genome shotgun sequence.
ACCESSION   DAIGUC010000065 DAIGUC010000000
VERSION     DAIGUC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.066"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            137..310
                     /locus_tag="NOB46_002322"
     CDS             137..310
                     /locus_tag="NOB46_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059233.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="NOB46_002323"
     CDS             950..1423
                     /locus_tag="NOB46_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCI1059234.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="NOB46_002324"
     CDS             1432..1659
                     /locus_tag="NOB46_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059235.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="NOB46_002325"
     CDS             2295..2666
                     /locus_tag="NOB46_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059236.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="NOB46_002326"
     CDS             complement(2922..3164)
                     /locus_tag="NOB46_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1059237.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="NOB46_002327"
     CDS             complement(3196..4098)
                     /locus_tag="NOB46_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI1059238.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4111..4299)
                     /locus_tag="NOB46_002328"
     CDS             complement(4111..4299)
                     /locus_tag="NOB46_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI1059239.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="NOB46_002329"
     CDS             complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="NOB46_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI1059240.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4914..5807)
                     /locus_tag="NOB46_002330"
     CDS             complement(4914..5807)
                     /locus_tag="NOB46_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1059241.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5885..6808)
                     /locus_tag="NOB46_002331"
     CDS             complement(5885..6808)
                     /locus_tag="NOB46_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI1059242.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6857..7207)
                     /locus_tag="NOB46_002332"
     CDS             complement(6857..7207)
                     /locus_tag="NOB46_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI1059243.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7240..8142)
                     /locus_tag="NOB46_002333"
     CDS             complement(7240..8142)
                     /locus_tag="NOB46_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI1059244.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8135..8992)
                     /locus_tag="NOB46_002334"
     CDS             complement(8135..8992)
                     /locus_tag="NOB46_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI1059245.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9326..10135
                     /locus_tag="NOB46_002335"
     CDS             9326..10135
                     /locus_tag="NOB46_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1059246.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10175..10672
                     /locus_tag="NOB46_002336"
     CDS             10175..10672
                     /locus_tag="NOB46_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI1059247.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11057..11130)
                     /locus_tag="NOB46_002337"
     tRNA            complement(11057..11130)
                     /locus_tag="NOB46_002337"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11094..11096),aa:Ile,seq:cat)
     gene            11317..11640
                     /locus_tag="NOB46_002338"
     CDS             11317..11640
                     /locus_tag="NOB46_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059248.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11804..12058
                     /locus_tag="NOB46_002339"
     CDS             11804..12058
                     /locus_tag="NOB46_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059249.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12128..12373
                     /locus_tag="NOB46_002340"
     CDS             12128..12373
                     /locus_tag="NOB46_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059250.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12449..12814
                     /locus_tag="NOB46_002341"
     CDS             12449..12814
                     /locus_tag="NOB46_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059251.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12875..13438)
                     /locus_tag="NOB46_002342"
     CDS             complement(12875..13438)
                     /locus_tag="NOB46_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059252.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4089 a         2577 c         2304 g         4978 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
     4141 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
     4201 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
     4261 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
     4321 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
     4381 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
     4441 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
     4501 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
     4561 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
     4621 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
     4681 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
     4741 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
     4801 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
     4861 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
     4921 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
     4981 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
     5041 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
     5101 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
     5161 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
     5221 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
     5281 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
     5341 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
     5401 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
     5461 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc atctttcacg
     5521 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
     5581 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
     5641 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
     5701 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
     5761 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
     5821 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
     5881 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
     5941 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
     6001 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
     6061 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
     6121 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
     6181 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
     6241 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
     6301 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
     6361 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
     6421 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
     6481 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
     6541 caaaagatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
     6601 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
     6661 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
     6721 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
     6781 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
     6841 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
     6901 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
     6961 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcga
     7021 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
     7081 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
     7141 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
     7201 tttccattcc tactccccct cttcagttgt tgtcttctat tatttaacaa ctacatctgt
     7261 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
     7321 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
     7381 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
     7441 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
     7501 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
     7561 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
     7621 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
     7681 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
     7741 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
     7801 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
     7861 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
     7921 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
     7981 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
     8041 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
     8101 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
     8161 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
     8221 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
     8281 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
     8341 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
     8401 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
     8461 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
     8521 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
     8581 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
     8641 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
     8701 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
     8761 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
     8821 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
     8881 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
     8941 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
     9001 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
     9061 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
     9121 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaaaggtat tgaccaaaaa
     9181 ctactatata tagccacctt tttcttaaga atgttttttg aaaaaattca taatgacaaa
     9241 gcaagttagt ttcatttttt taaattctca tttaatctta aggtaacagg aaaatagata
     9301 tgtaaaaaga aagtaggaag ataaaatgaa actagcagcg attgatttag acggtacctt
     9361 gcttgatcga aatggaaaga taccagaaga aaatatccaa gcacttcgga aatttgatga
     9421 aaatggcgga atcgtaaccg tcgctaccgg aaggaacagc atttctgcta aagatatttt
     9481 ttccgaatta ggaatcggtg gctatttgat ttcttccaat ggttcactga ttgctgaaat
     9541 gaaggatgga aaaatggcga aagttctcag acgttcaaaa atagatagcg atacactgag
     9601 aaaagccttc ttctatgctc aagaagcgaa aatatccatc attgctagcc gagaaaccca
     9661 agatgatcag ctgacattcg atgaatcaaa tctagtcaaa gatgaccctt attatgaaca
     9721 tttcaattta cagaaccatt cttttgatca aattttaaat atgttggaag atccttctct
     9781 tagctatctt aaattagcat taacagataa gagtgaagaa aaactacaga agctacaaag
     9841 agatctgcaa gcagatggta tccaatcagt attctctgat ccgcatttct tagaaatcac
     9901 gcctacaggt atcactaaag ctcattcact tgtttttctg gcggattacc ttggaatcga
     9961 atcgagtgac atcatggctt ttggcgatca agaaaacgac attgctatgt tgaattacag
    10021 cgggttgagt attgcgatgg ggaatgcaca gcgacaagta aaagaaattg caaaccaagt
    10081 aacactgacg aatgaagaag ctggtgttgc ttatatttta aaaaacttct attaaaaaga
    10141 ataaaatgac gatatgaatg taggaggaaa gaaaatgtta gttattattg atatgcaaaa
    10201 tcatattctt gatccaaaca gcgaatttta tattccagag tcagatcaat tggcagaacg
    10261 tattgctcaa agattagcta aagcacgcca aaataatgaa tatattctct tcacacggga
    10321 tataccagtt gaactgaagg acaaagaaga agaacgagaa gatttgcaat tgatccctct
    10381 tctttctcca caagaaaatg aacgagtgat taaaaagtat tactttacga ttccacctga
    10441 aactttagct gaaatccagg aaactttatt tgaaagcaaa gaagaacaaa aagagatcga
    10501 agtagtcggg attgaaacaa acttgtgtgt actctctaat ctgataggcc tgcagagtgc
    10561 ttttcctgaa gcagactttt ttgttgatcc aatgttagtc tccagtagaa aacacggaga
    10621 atccgcttta gagctgttga aagatttcaa cgtctctatc gtcgaatcat aaaaatatct
    10681 atcttcattt acgatattta acacacaata aaaaaagcac gcagaactgt tttagtccta
    10741 cgtgcttttt ctatcaaagt agattggctt ttttatgaca cagagtgaaa cggcaggctc
    10801 acgacctctt tcttaaatgg tgttcaatca gctgaccctc ggtattagct taacaaacgg
    10861 caaaatatga ggaactattt ttccgtttgt taagctaata ctcaggtcaa aacgctgatt
    10921 tcacaacctc ttccttaaac ggtattcaaa agcttgcatc tgcagtaata agaacagcca
    10981 agtaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct
    11041 ttttcacaac ctcttatgta ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
    11101 gtctgctcta accaactgag ctaaaggtac atcataaata aaatttattt ttgttacttt
    11161 tcaactatag cacgaatgac aaactctcac aagtttcaaa atataagtaa aataatattg
    11221 ttattcttat ttcttttact tgtgtcataa ctattttgtt actttaattt ttatttgctt
    11281 attttagaaa aaatgttatt cttttattta ttctcaatgt taggagtgat tattttgcca
    11341 tttattgcga ttttattcga tttagttgcg gcagcagctt attttctcca attaaattat
    11401 caaacctcag gaattctgtt tattggaatg atttttcaag gtgtgattac ccttttgctt
    11461 cttgtcatga tgctcagcta taaaggaaaa agatatgccc gtattcaaac aaaagtattt
    11521 gttaaatatg tttccattcg ctatgggatc atcattcttt cctttttagt gaatgcgatc
    11581 gtcctctttt tatatgtatt gaattactta gatatcaatc cattgatttt ttctcgatag
    11641 ataagacaca ttcagcggaa cagttcctgc ttatcagcag aaaactgttc tgctttttca
    11701 tttttcattg atctattctt cttttatttt cctagcattt catttgtgat gtatgcaata
    11761 acatgttatc ttttattata tgaatcgttg aggagtccgt tacatgatta cgttggtgag
    11821 agttttgttt tgggtgcctg cggtcgcact ggtcgcaagt attgtttatc ttatgaattg
    11881 gaacaaagaa cggttttatt tagctatttt gactcttccg gctatctact ttatgtggaa
    11941 agtttttaat tacaactact ttgaacccga tagtgttttt atagaagaat tatcaggact
    12001 ggttttgtct ttattgatcg tcattcttta tttgatacgt ttaaataaaa aacattgagt
    12061 actattgatt gcatgtgtag ctttctatag tcattataac tattctacta taatgaaagg
    12121 tgattaaatg agtatcgaag aagctatttt actggatact ttacgttgtc gtctgaattt
    12181 cttaagaact ggccgatctt tatctcaagt agctgtttct agcgcgttaa gtattccttt
    12241 attcaaatat cgtaagtacg aagaaggaga agaaattcca agcatcattg aattaatcta
    12301 tatcgctgac ttttacgata tttccgttga ttacctaatt ggtcgctcag aaacagcaag
    12361 caaactgaag tgattttttc cagccttggt gctggttttt tcatttaacg tctaaggtta
    12421 acaatctata tataaaggag acatttctat gcgattatgg catgaaaaat tgatttcaaa
    12481 gcttcctcgt caacagcttt taggacaaca tcgggaatgc tgtgcattaa gaggaaatgg
    12541 ctggggaaag aaacatgcta ctgtggatta tgtttttcac tattctcctt atagattatt
    12601 ccaatatcat cagcttgtca tggatgaaat ggaaaaacgt ggttacagcc cagcaccaga
    12661 gtggaaaaat cctatgtatc gtggcaaatc atgcgaagca ttttttgatt tacctactgt
    12721 agagcgcaac gtgccgattt atccggaaca cgatgaagtt tatctagcag aatgtttagc
    12781 aaatttggag caaaaaggaa tttatcttac ctaatataac tagaaaagcc ttctatctcc
    12841 tcttacttca ttaaaaagct ttaaccatct tagatcaagc taaaatgtcg taagttttag
    12901 ggttatcttc atcctcacgt gcaaaactaa aagcgtactc tagttttggt tcatcgccaa
    12961 cttccctaga cataaatgaa catctcctga cgtggtttaa aagtaccgca tcttcgacgt
    13021 ctgtatacga tgcacagcac agattgcttc ttttgatctt tcttttgatt tttctgttgc
    13081 ttcttctaca ccttcttcga ttactacatc gatgcttaca attgcttctg cctaatattc
    13141 ccatgcatcg tcgatttaag cctctgtagt cactgtgatc gtttccacat tttaactcct
    13201 ctgtcgtggc ttcagttgat tttgtgatca gttcagttgc taagccagag tcagaacaac
    13261 ctgccattgc tagcgttaat attgatagta aaaatagttt ttttatcata aggttccccc
    13321 cctgaaaata gactaaaata ataacgcttt ctttttttgt tttcagacga aaattaataa
    13381 tttctaaata ttctttaaaa aagcttataa ctattatgcc ttttttaata tataacacag
    13441 ttatttttaa aaataagaat gctaaatcac tctacaataa cggcgaaagc acaaaaaata
    13501 aaaaaattat tacgttatta aaaaaacaga tgaaagatca ggttttatta gatctcattc
    13561 tttcatcact tgaagggatt taatgaacta ctttttcctc tttgtcgttt ttatatattc
    13621 gtattccttc aaacagtagg atagcctctt tcaatgcttg atatttgaac tgtccgttac
    13681 ttaaaaattt agatgtgccg ccctcttcct agaacatatt cttttttact ttttcattaa
    13741 ttgacagacc aatcgaacga aactgtaaat ttcgatagga taatgattgg tcaaactcat
    13801 tcattttcaa gacatctcga ttcatattca agataggaat ctttttatca acatcacttt
    13861 attcgtattt tcctctacca taaaagcttc acgctccaca aaattgtttt atacactact
    13921 attcagccca ttcaacgacc aatgaatt
//
LOCUS       DAIGUC010000066        13924 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.067, whole genome shotgun sequence.
ACCESSION   DAIGUC010000066 DAIGUC010000000
VERSION     DAIGUC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.067"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            79..2008
                     /locus_tag="NOB46_002343"
                     /pseudo
     CDS             79..2008
                     /locus_tag="NOB46_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            2134..2688
                     /locus_tag="NOB46_002344"
     CDS             2134..2688
                     /locus_tag="NOB46_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCI1059253.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQFFVLYAVEYRKMFQRK"
     gene            complement(3418..3732)
                     /locus_tag="NOB46_002345"
     CDS             complement(3418..3732)
                     /locus_tag="NOB46_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCI1059254.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(3746..4006)
                     /locus_tag="NOB46_002346"
     CDS             complement(3746..4006)
                     /locus_tag="NOB46_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCI1059255.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            4176..4490
                     /locus_tag="NOB46_002347"
     CDS             4176..4490
                     /locus_tag="NOB46_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI1059256.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4492..6147
                     /locus_tag="NOB46_002348"
     CDS             4492..6147
                     /locus_tag="NOB46_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI1059257.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            6230..8365
                     /locus_tag="NOB46_002349"
     CDS             6230..8365
                     /locus_tag="NOB46_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1059258.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            8540..9049
                     /locus_tag="NOB46_002350"
     CDS             8540..9049
                     /locus_tag="NOB46_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059259.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            9046..10350
                     /locus_tag="NOB46_002351"
     CDS             9046..10350
                     /locus_tag="NOB46_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1059260.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            10446..11315
                     /locus_tag="NOB46_002352"
     CDS             10446..11315
                     /locus_tag="NOB46_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI1059261.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(11427..11747)
                     /locus_tag="NOB46_002353"
     CDS             complement(11427..11747)
                     /locus_tag="NOB46_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCI1059262.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            11850..12296
                     /gene="dhaM"
                     /locus_tag="NOB46_002354"
     CDS             11850..12296
                     /gene="dhaM"
                     /locus_tag="NOB46_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HCI1059263.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            12271..13281
                     /gene="dhaK"
                     /locus_tag="NOB46_002355"
     CDS             12271..13281
                     /gene="dhaK"
                     /locus_tag="NOB46_002355"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HCI1059264.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            13309..13914
                     /gene="dhaL"
                     /locus_tag="NOB46_002356"
     CDS             13309..13914
                     /gene="dhaL"
                     /locus_tag="NOB46_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HCI1059265.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
BASE COUNT         4664 a         2445 c         2956 g         3859 t
ORIGIN      
        1 gctgtgttct atccttttat ttatctctag gcccttattt attttgggac aggtatctct
       61 tcaagaaaag gagagaatat ggacaacgaa atgattagtc aattacaatt tgatcggatc
      121 aaaaaggaaa tccaagcaag agcaattgga aactatagca aaaaacgaat cagcgatatg
      181 acggtctcga caaacctaca aactgtcttg gatcgtcaag aagaaacaag agaagcacgc
      241 ttgatcttag aaagcagtca gcatgttcca tttatggggt tgccgaggat cgatgcactg
      301 acagaacaag tcaaaaaagg gttgattctg cagccaactg atttgatcga atatgcggat
      361 tttcttagaa gcagtcggat gatcacaaag ttttttgata agaatcaata ccagacaccc
      421 ttgttgtttg cttatagcaa acatcttcct gatttgataa atgtagaaga gttgattgac
      481 cagaaaataa aaaataataa agtcagtgac gacgcgtcac gtaatttgcg taaagtacgc
      541 aaacaattac aactaatcga aaaagaaatc cagtcaaaat tactgaaatt cttgcgtcat
      601 ccgaaaaaca aagaaatgat ccaagaagca atgattgttc aaaaaggcga atactatacg
      661 attcctatca aagccagcta taaaaataaa atagatggaa cgattatcga tgaatcaaat
      721 aaaagaacga cggtttttat tgaaccaact gtgatttcta aattgaatga acactatcag
      781 ttgttaaaag ctgaagaaat cagtgaagaa tatcaagtcc tggcggcatt gactggtgct
      841 atcgcagaaa acgaagaagt gatcgattta ttgatcgaaa cgatcacggt gttagatatc
      901 atctttgctc gggcaaaatt tagccgagaa atcaatggaa gcacacctag aatcaataaa
      961 tcggaacata tcattatcaa gcaaggcaga catccatttt tacctgagca tgcggtacca
     1021 ttggatgttg aaatcggtaa agactatcga ggcttgatta tcaccggagc aaatgccgga
     1081 ggcaaaacag tcgtgttgaa gacagtcggt ttattgactt tgatggcgat gttcggtatg
     1141 caagttccgg caaaagaagg gacagagctt gctgtctttg atgagatttt cgtcgatgtc
     1201 ggtgaccacc aaaatttaga aaatgcgttg agtacatttt ctggtcatat gcaaaacatc
     1261 gctgctattt tgaaaaagat aaaaaggaat acgttggtac ttttagatga gattggcagt
     1321 ggaacagagc caaatgaagg ggctgcacta gcgatcgcaa tcatggaatc tatgtatgag
     1381 caaggggcat tgatcattgc cacgacccat tatggagaaa tcaagaaatt cgccggagat
     1441 catgaagatt ttgtgccggc tgctatggct ttcgatcggg aagcacttcg tcctaaatat
     1501 cagttgcggg ttggaagaaa caggagaaag ccaagctttg tggattgctc ataaaatgga
     1561 tatgtcgatg aaattgatcc atcaagcaga gcgttacttg gcggaaaaag cctatcggac
     1621 acagaaaaaa gaatttcttc ctaagacagc agttacaaat aggaaggaga ataaaaaaga
     1681 acgtcagctc tttgcaaaag gtgatcggat atttgtcaat gaataccaaa aagaagcgtt
     1741 agtttatgaa gatataggtg aagatacgat tgatgtatat ttagacaaaa aaataatcca
     1801 cgtgcctcgt cagcgtgttc gtctggtgcg ttcagcagaa gatctgtacc cgacaggtta
     1861 cgatttagac agtctgttta tcgattataa aacacgtaaa cggcagcgtg acctagagcg
     1921 aggatcaaaa aaagctcata aagtactagt aaaagaaatg cgcaaacgac aggaagaaag
     1981 aagagtaaac gatgaaaaca gcaagtgatt atctcaaatt agctcataat atcagtgtct
     2041 gtaaagaaaa ataaaaacag tgaaatcatt ggttttattc cccgtgtaag ctaaaataaa
     2101 aagaaaagag tgctgaggag gtagggcgat aaaatgaaat taagcacaga ctggcgtaaa
     2161 gaaatacaaa cgattccgaa tcttttatcg atattccgta tttttttgct gccgatttat
     2221 ctttattttg tgctgagaca gtcattttat atagcaggag cggtcattgt tgtctcaggt
     2281 ttgtctgatt atctagacgg ggtcattgct cggagatata atcaggtaac agacttaggg
     2341 aaggtgcttg atccgtttgc agataaattg acacaacttt ttctgatttt gtctatggca
     2401 tggtatcgac cgtggctttg gctgttgttt ggtctattct tgataaaaga aggctttatg
     2461 tttgtagctg gattaatcgg gctatctaaa aatatcaaat taagtggagc gaagtggtat
     2521 ggcaaagtag cgactgctgt catctatgtt ggcatgatcc ttttgctgct tttcccagaa
     2581 ttaccaacgc tgtgggtgag agtcattttt gccgtcatca cttacggtct tttacaattt
     2641 tttgtcttgt atgctgtcga gtaccgaaag atgtttcaaa gaaaataaaa aaggggtgtg
     2701 acctatgtcg cattcctttt tttgataaat agactcccag tagctacttc tcgataataa
     2761 gccaaccgaa ccaaaaacag gagaagttgt ttttgaaatt atttcttgtg attcggagtt
     2821 aaatggtagg ctcacaacct cttggtaaac ggtgttcaat cagctgacct tcggtattag
     2881 ctcaaaaaac ggcaaaatat gagcagctat ttttccgttt gtttctctaa tactcaggtc
     2941 aaaccgctga ttttacaacc tcttccttaa acggtattca aaagccagtt tctcggtatt
     3001 aagccaaatt tatgcaaaaa tgtagaaatc cattttcaca aaatttttct taatactcga
     3061 aactaagcga ctttttcaca atctcttcct taaacggtgt tcaatcagct gaccttcggt
     3121 attagctcaa aaaacggcaa aatatgagga gctattttcc cgtttttttc tctaatactt
     3181 aggtcaaacc gctgatttca caacctcttc cttaaacggt gttcaaaagc ttgcatctgc
     3241 ggtaataagc ccaaccaaac gaaaaatatg agaagctatt tttgtttggc tgttcttatt
     3301 acttgatgca ggacagcgtt ttcacaacct ttgattcacg gttttccaga agtagcttct
     3361 tcgaaaaata agccgaaatt tcttgaagct gatcacttct gtcgcaacct ctactgacta
     3421 aggcttgata taagcataac cttgggattg cagttcaact aaatcaagga cacctgctgg
     3481 tacaacgatt acttgttcag gtaaagaact ttctgaaata tgattagcac gcatagcatt
     3541 ggcgcaagcg tgaaaaacga ctccttgcaa atctaagaat tctgcattgg cagagtctag
     3601 ataaccggta atcgcgatgc catttacaga tacgacaatc gtcgtttctg gagaagcttt
     3661 tatcaggttt tttacgtttt tccctgtttc tgaccatttt tctaattcat caatatggaa
     3721 aacgactttc attgaaatca ttcctttact ttttaataat catcttgatc gcttgttcta
     3781 gtttagccgc ttgttcttct ggattactat caggtttctc aaagcaattt ttcagattat
     3841 ctgcaacgat catgcccatt acgcgatcaa tactagaacg aacagcgctt aattgagtga
     3901 tgacatccat acattctttt tcgtcttcga tcattttttg gataccacga atttgtccct
     3961 ctgtacgttt caaacggttc aggatatttt tattatcaat ctccataaca cattctcctc
     4021 tatttttata attagataat accccttatc ggtattttat gcaaatataa aaagtagtga
     4081 aaaaaatgaa gagtcattct ggttgacata ttaataaagc tcctgtttaa tataccccat
     4141 gaggtattta taaaaatgta aatgaggtgc agaaaatgaa tttgctattt caatcaataa
     4201 aatcgataac agtcccagaa ttaaaggaaa agcttttgga aaatccagcg ttacttgatg
     4261 ttagaacacc tgcagaatac cggggcgggc atataaaagg agctaaaaat gttccattac
     4321 aaagtataaa cagatatgat ggagacaaag aaaagaccgt ctatgtgatt tgtcaatcag
     4381 ggatgaggag taaacaagca gctaaagaat taaagaaatc tggttatgat gtagtgaatg
     4441 tacgtggtgg catgaatcaa tggtttgatc gaacagtagg agggaaataa gatgaaaatc
     4501 gttattgtcg gaggtgtagc aggtggaatg tctgctgcta cacggcttcg ccgattaatg
     4561 gaagatgcag aaatcgttgt ttttgaaaaa ggaccgtatg tttcttttgc aaattgcggc
     4621 ttgccttatt atctttcggg agaaatcagt gaacgggaaa atcttcttgt ccaaacgcca
     4681 gaatcattat ccgctcgttt ttgtttagat gtgcgtccaa atcatgaagt gacagccatc
     4741 tttcccgaaa acaaaacggt agaagtcgta catgagggtc aaaaacacat tgaacagtac
     4801 gatgcattgg ttttatctcc tggtgcaaaa ccagttgttc catcgattcc agggataaca
     4861 gaagccgaca atgttttttc tattagaaat gtaccagata tcgataaagt gatgcatgca
     4921 ttagaaaaac agccaaagcg tgccgtgatc gttggtgcag gattcatcgg attggaaatg
     4981 gcagaaaacc taaaaagaag aggtttagaa gtcatggtga tcgaacaagc accacatatt
     5041 cttccaacac tggatgaaga aatggcagct tttatagaaa aagaattgtc tcatcaagga
     5101 gtagaagtga ttacttctca tgctgtcgct ggatttgaag accacgggaa acgattgcga
     5161 ctggatgatg ggcgtaccat ccctgctgat ttagttattt tatccattgg tgttcgtcct
     5221 gataaccagc tagcagtgac cgctggaatc gaattaggca tacgcggggg tatcctagta
     5281 gacgaacgtt atcaaacgaa tattcctgat atttatgcgg tgggggatgc tatcgttgta
     5341 aaacagcaaa tcactggaaa agatgcactt atttctcttg cttcaccagc caatcgtcaa
     5401 ggtagacaag ttgcggacac gatttccgga atttctcgaa gaaatcaagg cggtattgga
     5461 acagcaatta tacgaacgtt tggaatgact gccgcatcca ccggtttaag tgaaagaaca
     5521 gccaaagaaa acgaactgtc ttttgaagtc attcatgtat caggaaaaga tcatgcaagc
     5581 tattatccag aagcaacaga tattttactg aagttgatct tccatccaga gactggcgag
     5641 atttatggtg cacaaggtgt tggggcaaaa ggtgtggata aacggatcga tattttagca
     5701 acagcaatca aagggcattt gacgatcttc gatttaccgg aattagaatt gacgtatgca
     5761 ccgccatttg gctcagccaa agatccagta aacatgctag gatatgcagc aatgaacatt
     5821 gcagaagggc ttagtgaaac cgtacaatgg catgaattgc cgacagaact agcaaaagga
     5881 aaaattttat tagatgtgcg aacagcagaa gaattggaaa agggcaaatt caaggaagcc
     5941 aaacatatcc ctttgaatga acttcgggac cgattaaatg aattagacag ccaacaagaa
     6001 tatatcgtca gctgtcatag cggattacgt agctatctag cggaaagaat cttgaagcag
     6061 tctggctacc acgtaaaaaa ccttgatggt gcattttctt tatatcaaac tgtccgacct
     6121 gaagaactga tatatcctaa caaatgatac tcgttaaaaa gcttgcattc gactcttaaa
     6181 agaggtaaac taatcggttc caccacttta aaaaaagagg agaatgtgta tggtcaacac
     6241 acaaaaacag ttagaagaag catatctgaa gaacgtgtat caaaagctaa ttgataaaaa
     6301 aaacgaactg cgggaatcga tggatacggc aaaaatagaa ggaaaccagt cgttgaaaga
     6361 aatggctggc gagcttcgat tgaattttga cagttactta gataacctgg atactttttc
     6421 gatgattgaa atgaaaaata gagaaatcga tcagatgaat atcaaacaga aaaacgcaga
     6481 aaatcagcta gcaaagatcg aacgtttatt gaaaagtccc tactttggaa aagtcgttgt
     6541 agactttctg gataatgagc caaaagaatc cttttatatc ggtacagcaa atttcacaga
     6601 tgatgcagat gaaaatcttg tttatgattg gcgttcacca attgccgaac ttttttacaa
     6661 taacatgatt ggtccatctt cttatacggt tcgtcaaaat aaaatcgata cggttattaa
     6721 agaaagacga caatttcttt tggaaagaga tcgtttggtc aagttttttg atacgtctgt
     6781 agctattcaa gatgacgtat tattagaagt cttaggccaa gatgagacca atgaaatgaa
     6841 ggctatcact gctacgatcc aatcggaaca aaacacaatc attcgggatg tgaaaagtca
     6901 aaatatcttg gtaaatggcg tagcaggaag tggtaaaacc tctgctatca tgcagcgtat
     6961 tgcgtatctg ctctatttat atcgagatac gatgacatcc gatgacttgc tgattctatc
     7021 acctaatcat cggtttatcg actatatttc gaatgtccta ccatcattag gtgaaagaaa
     7081 tccactgaat ctaaccatca tacagctggt ttcacagctt tcagcagagg aaatagaagg
     7141 tgaagaggct tatttcaaac gtatcacggg agaaaatgta tcggagcaga cagaacgttt
     7201 gcgtagcaaa aagtttatcg ataatctaaa acaatcagat cctttgtttt tagatcatcc
     7261 gaattttatc cgtggactta ctaaaaatgg aaaaacagtc ctttctaaaa aaacgatcga
     7321 aaaaatatat gagaaagttc ctgctcatcc taaattgatc gataggcttc aagcaacgaa
     7381 aaaggcactg atgagcgaat ggaagaatca tcttttgaaa caagcaaaaa gtcctgctgt
     7441 gcagaatcag gtactctcgt tgacagaaga taggcagttg gaattattcg gtaaattgat
     7501 ttctgatgat tcggaacaaa gtattgtagc ttatgcaagg aaacttttac aaaaaaaata
     7561 tcgaaaaata accagacaaa tcgaagaaat ggcatgggtg gatgagcatc agttgtttga
     7621 aagaatttat gaaaaacgat atggctcagc ttatgcttgg caacccacac gtactgttga
     7681 tgaagcagtc attatattag ctattcgtca tttacttgtt gaaaaggtaa atgtaccagc
     7741 atttcgctat ctattgattg atgaagtaca agattatacc ctggcacaat taggtctatt
     7801 gatcgaatta tttccaaaaa ctcactttac tttagtaggt gacgagaatc aggcaatctt
     7861 taattcttcc actacttttg ctgatattat gcgttgtttc gacgactacc atctgccgat
     7921 ccatcggtat gatcttagaa atagttaccg ttctagcgga gcaatcacag agcttttcaa
     7981 aacctatgct gtggatcaag agaagatcga catcgtatcg atccgaccgc aaggaaaaga
     8041 acccgaatac cgctcttttc gatcctctga agaattgttg aaaatactag ctgagatttt
     8101 ggtttctcta aaaggagaaa aagcggcagt tatcacccaa acagaagagg aaacccaaac
     8161 gctacaagaa tcgattaaaa aaaattcata tggattagaa aactgccaaa tcattccttt
     8221 gagtctagca aaaggactgg aatttgatca tgtaatctta tatccatttg aaaacgatgg
     8281 agatgagcaa agaagacgca gacaaatgta cacggcgata tctagaggaa tgaaaagcat
     8341 tgtcgtattg gaaagagcaa cataattaag agataaaaaa taaaaagaac aactgataaa
     8401 aagaacaaaa tatttttcat ttgctgatga gaaatgtttt gttctttttc ttaggaaaaa
     8461 tttaggaaca ctttatgtga aaagaaatga aatgtatggt aaactcctac gtcgtaacaa
     8521 aaaaacgtga ggtgaggata tgaaaaaagt aacaagagaa gaagttgcat caattttggt
     8581 gaaagataag tatttttcaa aaggtaatta ctggttaaag atttggcaaa cgttagtggc
     8641 tcttttagga tggatgatcg ttgttcttcc ttttatatgg gtctttttcc cattaacgag
     8701 accagaaaga gccaaggatt tttccttgta cgctttttta tcagaaaaga aaatgctgta
     8761 tttcttaatc ggcttttttg tattgatttt tttcagtttc ctgattacct catttgtatt
     8821 gactaggtgg aacaatcgaa atctatacaa aaaagtaaat aaatcttttg aatatgaaga
     8881 tgaaaaattg aaaaaaagac aagaattact tgaagaagtg tatacggaac gttttggaac
     8941 aaaagaagag agagaaacgg tccgttttta ttctgtctcc gaagagaaaa atctagatac
     9001 gacattcatt gcagatttgt ataaagaaaa tggggtggaa ctgaaatgat ctcaatcacc
     9061 catacaggta atttattctt agatacttgt ttgtctatta tgtatttttt tctcgtttct
     9121 tatccgattt taggcggatt tgtatggttt attggtgtct ggtgttatgt gtttttatac
     9181 aaacataagc aaaaagaatg ggtagatgtt cccttgagtg tcgaaccgtt catcacgatc
     9241 atggtgccag cccataatga agaaattgtg atcgaatata caatcgagta tttgatgacg
     9301 aaattgaatt atcacaacta tgaggtatta gtgacagacg atggttcaac ggaccaaaca
     9361 ccagaaatat tagctagact gatgaaaaaa tacgctaatc ttcgtgtggt tcggatcgaa
     9421 aaaaataaag gaaaagccca cgcgtttaat atcggacttg cctttgcaaa agggaaattg
     9481 attttaagca atgatgcaga cacggtaccg gagccagatg cactgattag gtatgtgaat
     9541 tatttcattc gccctggtgc aagacatatt gctgcggtca ctgcaaatat ggatgtccaa
     9601 aatcgtacca aattgattgc aaaatctcaa acggttgaat tctcaagtat cgtgggcatc
     9661 attaaacgaa cacagtcagc tgttttcggt ggtctttatg cgtacagtgg agcaaatacg
     9721 atgtatcgaa aagaagcctt gatcgatgtg ggcggattca gacaagatcg agcgacagaa
     9781 gacatcagta ttgcttggga tcatcagtta aatgactggt tatctgtttt tgctcctgag
     9841 attatctttt tcatggaagt acctgtgacg ttgaagatgc tatatcgaca cagaaaacgt
     9901 tgggcaaaag gtggaacaga agtctggctg acgaatttca aaaaagtgat gctccatcct
     9961 tttaaacata ttggaagaac gatcatcttc attgatcaaa cattgagtat tgtctggtca
    10021 atattctttt gtatttccgt agttcttttt gctggattaa tcgggcatta tgtatatcaa
    10081 ggaaactacg aacagattta tattactttt acattcagtt ttgtgttcat ctgctttgaa
    10141 atggtcgcag gatttttcca gttgctagct tcgctgattg tagatgatcg acgaagaaaa
    10201 ttgaaatacc ttcttttcgc accactatat atgcttttgt tctggatagt gaacgcgata
    10261 acgatcgtga cgactttcat tccagcagtc aaaacgattt taggttatgg aagcgggaca
    10321 tggaaaagcc cggaacgtac aaaaaaataa aagatgcacc gttttttaga caaacagcct
    10381 gttgtgttta tggttcttcc aaacattttt gcttataata agaaattagt taaaaagtag
    10441 taaggatggg aaaagtgatg aaaaaaagaa tgaagccgtt aatctggcca attgctgttt
    10501 ccagtatttt cttattggga cagacagctt ttgcggaaac ttctgaacct gctcaaacag
    10561 aaccttcaac aaccataagc tcttctggtg ctgaaaacgg tgcctcggaa acagaaatga
    10621 cttccaatgt accgacagat aattcaggag aaacgatttc atcttcagaa gatacatcaa
    10681 taaatagttc tacctcttct gaccaaatcg atcatttgca agacttggaa aataaaagaa
    10741 aagaactcga agaagcatta gaagctgcaa aaaacaaatt gaaagaagac caagcagcaa
    10801 tcgatcaaga tttagctgat cttaaaaata aagtgggaaa tgaccgtgca caacttgaga
    10861 aaaagcttgc cgaagcgaaa gcaaaagcgg aagctgtcca aacagatctt gacgggaaga
    10921 tccaacaagc aaaagaattc aatcagcaat taaatcaggt tgctcaaaca gcttctggaa
    10981 agctaagtca aactcaagcg gatatcacag cggccagtca agcaatccac ggaaagatca
    11041 gcgaagcaca aacagttgct aatgattttg aagcaaaaaa agctgactta gcagctagtt
    11101 tccaacgaat aaaagatatt ttgcattcgg caggagaaaa atcagtgacc tctggaagca
    11161 cgacagaaac agttcagcaa acgacagagc catccaaatc aacaagtcag actttgccaa
    11221 aaacaaatga aaaaacagct tctgtcagtt attccttagc aggggcgggt gtgttagtcg
    11281 cagcagctta cggaatcatc cgcaaaaaga aataaaaaag agaggatggg aaggtagagt
    11341 acctcgaagt tagactgaaa aatctaattc ttgagtgcca ctacatgtcc catctctctt
    11401 tagttattaa aacagatgtc ccctacttat ctcgtggaga cagctgttcc actacatgtg
    11461 accatcagca tgccattgtc gctgcctaat acttcatagt ccatttttac gccaatgatc
    11521 gcatcagctc ctaatgcttt tgcacgttcg gccatttcgg caagtgcttc ttctcttgca
    11581 cccattagtt cgttttcata gctttttgag cggccgccaa agatatttcg caaccccgcc
    11641 tccaagtctt taaatgcatg gatcccagta atgacctcac caaaaacgat ccctttataa
    11701 gctactacgg cttttccctc tacactgttc gttgttgttg taatcattcg atcactcctc
    11761 tcttttaatt aaagtataac aaacttcaag aagcactaca catattttcc caaaattaga
    11821 aatttattat atacttgaat tgttcattaa tgaaagcgaa accaatcgtt agcaactatg
    11881 taaaagaaag gaagattctt gtgaaaaaaa gtattttgct tatttctcat agtcaaaaag
    11941 taacagatgg tattaaagaa atgattgagc agatgcaaaa atccgaagag gtgcaaattt
    12001 tttctctcgg cggaataaat ggcgagatcg gatcagaccc gatgaaaatc gtagaagcag
    12061 tcaatgaatc aagcgatgca gctagttatt ttgtttttgc ggatatcggt agcgcggtat
    12121 tgaactcgga actggcaaaa gacatgttgg aagaagagca gcagcaacgt tatcatctgg
    12181 tggatgcgcc tttagtggaa ggagcttttg cagcagccat cactgccggt ataacagatg
    12241 atactcagca aatcttaaca gaagcacaaa atgccggaaa gaaaggatgg gaataaattg
    12301 aaaaaaatca tgaatgatcc aagcaatatt gtcgaagaaa tgctggaagg attagtaaaa
    12361 agctatccag aacttgttca tcgtgtagaa tcttcccgtg ttgtagccaa gaatcagaaa
    12421 gcggaacaag ttggtttggt ttctggtgga ggaagcggac atgaaccatc ccatgccggg
    12481 tttgtagggg aagggatgtt aagtgcagcg gtgcttggtg atgtgtttac ttctccaact
    12541 ccagatcaga ttcagacggc tattaaggaa gccgatagtg gaaaaggagt tttgctgatc
    12601 gttaagaatt atacagggga tgcattgaac ttcgatatgg caaaggaatt agctgctatg
    12661 gacgatattg aagtagaaag tgtgatcgta gatgatgata tcgccgttga aaatagtacg
    12721 tatactgctg gaaaacgcgg agttgcaggt actgtccttg tacacaaaat cgtgggcgat
    12781 gcagcaagaa acggtgcttc cctagctgag ttgaaagaac tgggagaaaa ggtcgtacag
    12841 gcaactaaga cgatcggtct agcgcttcga gcagcaactg taccagaagt agggaaacca
    12901 ggattcgaac taggagaaga tgagatcgag tatggtgttg gtatccacgg tgagccaggc
    12961 tatcgtcgag aaaagatgca gccttctaaa gtactggcaa aggaacttgt tactaagatt
    13021 ttagatgatt actcgaattt accaaaagaa gcaggtgtac tagtcaacgg aatgggcggg
    13081 acgcctttga tggaacagtt cgtgttcatg aatgatgttt tagctctgtt ggaagaaaga
    13141 ggcgtcaatg tagttttccg aaaagtcggt aattttatga cctcactaga tatgcaaggt
    13201 ctttctctaa cactgatcga cttgacggag acacaatgga aagattcttt agaaagcaat
    13261 gtacagacga tttcatggta aaaaatctca agataaaagg gtgataatat gaaactaacc
    13321 gttcaagaaa tccaagaatg gctcacgcaa tttgcagagg caatcaatca gaacaaacaa
    13381 tatctcagtg atctagatac cccgattggc gatggagacc atggaaataa catgggaaga
    13441 ggggtttcag cttatgaaga agcttttcaa gccgatcatc ctgaaacaat cagcgataca
    13501 ttcaaagtat tctctatggc gatgatatcg aaagtcggtg gggcttctgg tccgttatac
    13561 ggatctgcat tcatgaacat gatgaaagcg acaaaagagg tcgattctat tgattctcaa
    13621 gaaaaattag gcgaagtgat cgagcaggga acagcgggta ttcaaagccg aggaaaggca
    13681 gaagctgacg ataaaacgat gttagatgtt tggctgccag tcacagaggc attgaaggca
    13741 gggaatttaa caaaagaaat cattgaccag gcaaaagaac acaccaaagt cttggtagct
    13801 aaaaaaggac gagcttccta tctaggagag cgtgcaatcg gacatatcga cccaggagct
    13861 gcttctagtg ccattttatt ttcaacgctt ttagatgtga tcaatcaacc ttaagttcaa
    13921 taaa
//
LOCUS       DAIGUC010000067        13850 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.068, whole genome shotgun sequence.
ACCESSION   DAIGUC010000067 DAIGUC010000000
VERSION     DAIGUC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.068"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..901)
                     /locus_tag="NOB46_002357"
     CDS             complement(<1..901)
                     /locus_tag="NOB46_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCI1059266.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(925..969)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1184..2152
                     /locus_tag="NOB46_002358"
     CDS             1184..2152
                     /locus_tag="NOB46_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1059267.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2265..2543
                     /locus_tag="NOB46_002359"
     CDS             2265..2543
                     /locus_tag="NOB46_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI1059268.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2661..2897
                     /gene="secG"
                     /locus_tag="NOB46_002360"
     CDS             2661..2897
                     /gene="secG"
                     /locus_tag="NOB46_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCI1059269.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3000..3755
                     /locus_tag="NOB46_002361"
     CDS             3000..3755
                     /locus_tag="NOB46_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI1059270.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3758..6115
                     /gene="rnr"
                     /locus_tag="NOB46_002362"
     CDS             3758..6115
                     /gene="rnr"
                     /locus_tag="NOB46_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCI1059271.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6137..6601
                     /gene="smpB"
                     /locus_tag="NOB46_002363"
     CDS             6137..6601
                     /gene="smpB"
                     /locus_tag="NOB46_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCI1059272.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6903..7622
                     /gene="atpB"
                     /locus_tag="NOB46_002364"
     CDS             6903..7622
                     /gene="atpB"
                     /locus_tag="NOB46_002364"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCI1059273.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7675..7890
                     /gene="atpE"
                     /locus_tag="NOB46_002365"
     CDS             7675..7890
                     /gene="atpE"
                     /locus_tag="NOB46_002365"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCI1059274.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7981..8505
                     /gene="atpF"
                     /locus_tag="NOB46_002366"
     CDS             7981..8505
                     /gene="atpF"
                     /locus_tag="NOB46_002366"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCI1059275.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8492..9034
                     /locus_tag="NOB46_002367"
     CDS             8492..9034
                     /locus_tag="NOB46_002367"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCI1059276.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9057..10613
                     /locus_tag="NOB46_002368"
     CDS             9057..10613
                     /locus_tag="NOB46_002368"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCI1059277.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10627..11529
                     /locus_tag="NOB46_002369"
     CDS             10627..11529
                     /locus_tag="NOB46_002369"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCI1059278.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11552..12958
                     /gene="atpD"
                     /locus_tag="NOB46_002370"
     CDS             11552..12958
                     /gene="atpD"
                     /locus_tag="NOB46_002370"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCI1059279.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12972..13394
                     /locus_tag="NOB46_002371"
     CDS             12972..13394
                     /locus_tag="NOB46_002371"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCI1059280.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4575 a         2473 c         3013 g         3789 t
ORIGIN      
        1 tttcggaaaa aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc
       61 aaaattcata acgatcaacc aatgtttgtc cacgacttat tccctgagtt tccacagcgg
      121 tgaagctttt gaaaccttca cagatggccc cctcgatgaa ataagcaaca gctaacggat
      181 cattgatgac acatcctaaa attctttctt gtttccagtg gaagtcaaaa taaaaacgag
      241 tgatcgcttt taaatactct ccctcttcag gattcatttg acagcagtat tcgaggatag
      301 tcggtgtcaa gacgatttct cttgtcacat ctaacccaac catttctatc gtttgtttga
      361 gattctcgaa tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg
      421 gcgaacagtt accatggctt ttgtaagttc cacccatcga gacaaaacga tccatatgtt
      481 tcccaatatt tgggttgact ttcaaagcaa aagcgatatt ggtcaaagga cccaaagcaa
      541 tgactgatgt atttgtcttt tctttgaaat aatcagccaa aaaatcaacg gcatggagag
      601 gttctgcctg ttttctcaag atcatcggga aatttgtttc ccctaaacca tccataccat
      661 gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt ttccattcct tgataaacag
      721 gaatgtctaa acgatcacag cgttccaggc atttcagcac attctgcgta cctatatctg
      781 cagggacatt cccacaaact acggtaatag caactacttc gatatcaggg gatttgacag
      841 ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca atcaataatt acttttcgca
      901 ttatttccaa tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac
      961 cagtccaaga cgagcgtctt gattataatg cacgaaatta gtatactggc ttttattgcg
     1021 aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa ctttaagtaa atgatacaat
     1081 gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat cctatggatc ggtacattgg
     1141 ataatagata gattatagtt tggcagaaag cggcgggtgt acaatggtta ttttttattt
     1201 cattcttatt ctgataatta tagggatcag ttaccatttt ctttcttatt tttatgcaaa
     1261 gaaattagta agagcgggag tacagagagg atatgactgg tatgaagaca ctggtcatcg
     1321 tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa cgacaaaaat tagaagaaga
     1381 gtgtgaaagc ttttgggagc agggaacacc caaaacaatc aaaagttatg acgggttgaa
     1441 actagctggt cagatgttca tccatccaaa taagcagaat aaatgggtca tttgcgtaca
     1501 tgattaccga agcacaggga aaagagacat gtctcatata ggtaaaagat atgcagagaa
     1561 aggattcaac gttcttgtac ctgatttacg tgcgcacgga gaaagtgaag gagaaatcat
     1621 cggaatggga tggctagatc ggctagattt aattgcctgg atccaactca tcttagatga
     1681 acagccgaat gcgtccatta ttttacacgg cggatcaatg ggagcttcta cgatcatgat
     1741 ggcaagtggt gaaaaacttc catcagcggt caaaggattt attttagaca gcggatatgt
     1801 ttctgtttat gcagaattcc gatatatgtt aagtaaaatc actgtctttc ctaaaaaaat
     1861 ggtcatgaga tatgcgaatc attatgccca gaaatacgcc ggttactcct taaagcaagc
     1921 atcagctacg agacagcttg gcagcaacca tctgccttta ttagtcatcc atggtgaaag
     1981 agatcatttt gtccctacag aagcagcgta cacgattcaa aatgctacgg caggggataa
     2041 agcactgctg cttgttccag aagcagaaca cttggaagca tcgatgaaag atccgaaaac
     2101 ctattggaca gtgatttttt catttattga acaaagaata acgatggatt aattttctct
     2161 tcttttttgt aagtaattcg aggataaata attgtttata gatctggaga ctgctaaaat
     2221 aaggtaggaa taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagaag
     2281 aaaaaaatcg tcttgcttta ttcaatgatg agcaacaaga gattggagaa atgacatggt
     2341 cagatgcggg cccagacatc atgatcattg accatacatt tgtagatcca gcatatcgtg
     2401 gtcaaaagtt agctgaaaag ctagtgtata ctggagtaga attagcaaga cgagacggga
     2461 aaaagatcat tcctttatgc ccttatgcaa aaaaagagtt tgaaaagaaa ccagaatatc
     2521 aagacgtctt acgtcagtca taagaataac agctgaaagt tttgaacttt cagctgttat
     2581 tccatttata tagagttgtc acggactttt atctatgata aagttaaaga gacgatatct
     2641 tttgggaagg aggctgcgat atgtataatt taattttggg aatcgtgatc gttttatcga
     2701 ttgttatggt cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat
     2761 ttaccggcgg tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca
     2821 tgcagcgatc aactgcagtt atgggagcta tctggatgat cttattattt gtcctagcat
     2881 atttatcttc gaagtagttg aataagcctc tcgcaaaacg gcgggcggct ttttttattg
     2941 caaagagaac gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg
     3001 tgagacgagt gagacaatta ccaaaacccc tttatgcaaa acatggaaag cgagcggttt
     3061 tgctgcttca cgcttactca ggaagtccaa acgatgttcg aatgctcgca cgatttttgg
     3121 aaaaagcaga ttatacagtt tatgcgccgc tttttaaagg acacggaaca atggagccat
     3181 atgatatctt gcaagaaaaa gcagaaagct ggtgggcaga cactaaaaaa gccatccatt
     3241 ttttacagtc tgagcagttt tctgatattg ccgtattagg attatcaatg ggcggcatct
     3301 ttgctgtacg agcactagaa gaagaatcag tgattggcgg cggttttttc tgttcgcctt
     3361 tgtctcctgt aaaaacaaac gtgcctgaaa actttgaaaa atacgtacgt caagtgctga
     3421 agacagcagg taaatcagag aaagaaatca atgaaaaagc agttgcttac cgctcgttag
     3481 ctgaacaaca attaatggat atacaagatc aggcagcaat cgtagaaagt aggttgtcag
     3541 atatccaaca gccgatattt ttagctcaag ctgggaaaga tgaaatgatc gaccctaatg
     3601 gcgtatttga aactgcacgc aagttgagcc gtcagcgagt gacacttcaa tggtatcctg
     3661 aaagtggtca tgtgattaca gttggtacag caagacgcga attagaaaaa gacgtcttgg
     3721 aatttttaga aaaattacct tggaatgagg aataaatatg acaaaagaaa cgataaaaga
     3781 gaaaattctc tttttcatgg aaagcagtcg caaacgcagt ttttctatgg aagaaatcgc
     3841 tgaaggttta gggttccaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca
     3901 aatggaaaga gaacagagta tagttttcaa taaaaaagga aaagtgaaac ttcctttaaa
     3961 accaatcttg atcgaaggaa catttcgagc aaatgaacga ggatttggat ttgtaacgat
     4021 tgatcccgaa gaagatgaca tctatatccc aaaagaagcg actggttttg caatggatgg
     4081 agacaccgta gcaatcgata tcatgaagcg agcaaataca gatatggatc gcggagcaga
     4141 ggggaaagta gtcgagattc gagaccgggc gactactcag ttagcagggg aattcgttgc
     4201 ttattcagaa gaagaaatac aagaaacaga tctttacggc gttgttatcc cgaaagatag
     4261 aaagctcaac caatttaaag tatatgcagc agcagaggga gttcgtccag ttgacggaag
     4321 tattgtgctg atcgaactga cccattaccc tgaaaaaggg tatgcgacta gtttagaagg
     4381 gataatcaag caagtgattg gtcataagaa tgaccctggc atggatatcc tctcaattgt
     4441 cgtggctaat ggtatcccta cgaaatttcc tgatgatgta ttgtctgaag cagatgaagt
     4501 tccagatcaa atcagcgaaa aggatataac tggacgtaga gatttaagaa atcagctcat
     4561 tgttacgatt gatggagaag atgcaaaaga tctagatgat gcagttacgg ttaaaaaatt
     4621 agataacggt aattattttc ttggagtaca cattgcagat gtttcttact atgtgacaca
     4681 aggcagtcaa ttggacagag aagcatatga aagagggaca agtgtatatt tgactgatcg
     4741 agtgattccg atgatcccgc aacgtttatc gaatggtatc tgttcactga atccccatgt
     4801 tccaaggctg accatgagtt gcgaaatgga gattgatcca aatggacaag tagtctctca
     4861 tgatattttc ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca
     4921 aatcttagaa gatcaagacg aagaaacgat gcaacgctat gctcagctcg tacctatgtt
     4981 ccaagaaatg ggtgaattgc atcgaatcct tgaaacgatg cgaatcaaac gtggcgcgat
     5041 ttcttttgag gatcgcgaag cgaaaatcct tgttgatgct gaaggacacc caaatgacat
     5101 ccagctaaga agcagaggaa ttggtgaacg cttgatcgaa tctttcatgc ttgcggccaa
     5161 tgaaacggta gctgaacatt ataataaatt aaatctgccg tttatttacc gaatccatga
     5221 acagccaaaa gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct
     5281 ggtccgagga acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt
     5341 agaagacaaa ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc
     5401 acgctattca gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt
     5461 tacatctcct attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag
     5521 tgaagataaa agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga
     5581 tcatagttct aagatggaac gtcgtgcagt agaaacagaa cgtgaagtag attccatgaa
     5641 gaaagcagaa ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt
     5701 tgtgaaattc ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa
     5761 tgaattgaaa caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag
     5821 aactggtctg acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc
     5881 agatgaacga gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg
     5941 tccaaaagca cgcaatggaa aatttggaaa acgagaagga aaacaagcag gcaaacgctc
     6001 agaaaaaaat ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa
     6061 aaaagggaaa aagccatttt acaaagatgt caaaaagaag aaaaagaaaa aataaaatga
     6121 gttggaggaa acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc
     6181 tcgccatgat tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga
     6241 gatcaagtcg atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa
     6301 cggggaagct ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa
     6361 tcatgatccg ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga
     6421 aaacgaattg aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg
     6481 ctatgccaag gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga
     6541 tttgaaacga aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata
     6601 atttcattat cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt
     6661 tagcatttaa tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt
     6721 gcatggggaa aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa
     6781 aatgttttga attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga
     6841 aaaaaccaga tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg
     6901 gattggatga acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt
     6961 gtataatggt gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa
     7021 atcttaagtt gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc
     7081 gaggaatcgt aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat
     7141 ttacattgtt tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct
     7201 tacctaacga aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt
     7261 tggcatttat aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag
     7321 gatatttcgt aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg
     7381 aagaatttac aaatttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg
     7441 aagttttgct aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat
     7501 tagcaattcc attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag
     7561 catttgtctt tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat
     7621 aatactcggt taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat
     7681 tatatcgcag cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt
     7741 caagttatct ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc
     7801 cgtacaacaa tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt
     7861 atcgccttga ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc
     7921 gtttgttact gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct
     7981 atgctgaatc aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt
     8041 gtcagcggct catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc
     8101 agcgatattt tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa
     8161 tctcgcatca actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt
     8221 tctgatgcag ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat
     8281 attttgaagg atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc
     8341 actgtagaac gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt
     8401 caaatcgcgg aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc
     8461 aatcaataca ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag
     8521 acgttacggg aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta
     8581 tcaagatctc gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt
     8641 aagtgatgtt cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg
     8701 ttatgatggg atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga
     8761 ccttttgttc atgatcgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt
     8821 gggaagtgtc acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa
     8881 tgttgcaaaa acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat
     8941 tattggtggc gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca
     9001 attagaaaaa atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg
     9061 ccatcaaagc agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg
     9121 tgctttcagt cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac
     9181 atggtttaga aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa
     9241 tggcgcaaaa cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca
     9301 ttcgtgaagg agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg
     9361 ccttgatcgg tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg
     9421 ttactgacaa agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg
     9481 ttaacgaacc aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg
     9541 gacaacgtga attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgatcgata
     9601 cgatcatcaa ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag
     9661 attctacagt tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa
     9721 tcgttgtgaa tgccggtgcg tctcaaccag caccattgct ttatatcgca ccatatgctg
     9781 gtactgcaat gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg
     9841 atctttcaaa acaagctgtt gcttatcgtg aactttcctt gctgcttcgc cgtccaccag
     9901 gtcgtgaagc ttatccaggg gatgttttct acttacactc acgcttattg gaacgtgcag
     9961 caaaattaag tgatgattta ggtggcggtt caatgactgc cttaccattt gttgaaacac
    10021 aagctggaga tatctctgct tatatcccaa caaacgttat ttcgatcact gatggacaaa
    10081 tcttcttaga aagcgacttg ttctacgcag gtactcgtcc agcggttgat gccggactat
    10141 ctgtatctcg tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt
    10201 tacgtctaga cttagcaagt taccgtgaat tagaagcatt tacacaattc ggttctgact
    10261 tggatgcagc aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac
    10321 aaaaattgca tgcaccgcta gctgttgaaa aacaagtagt gattttgtat gctttgacac
    10381 atggattctt agatagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg
    10441 aatatctgga taccaatcat tcagatatct ttgaaacaat ccgtacaaca aaagatcttc
    10501 cagaagaaga agcgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa
    10561 aaggaaataa ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg
    10621 agatgaatgg gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg
    10681 agccaaatca cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct
    10741 tcttcacaga agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact
    10801 gctactcagt taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc
    10861 atgttgctca gccgtcctgt taagaaaacg ggttatatcg tcatcactgc agatggcggt
    10921 ttagtcggtg gatataacag ctcgatattg aaacaaacga tgtctatttt agaagaagac
    10981 caccaatcac ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt
    11041 aaagcacgcg gtatcaatct agcatatgag ctgcgcaatc tatctgatca gccaagcttt
    11101 gatgaagtcc gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat
    11161 gaattatacg tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa
    11221 aaaatgctgc caatctcaga cttagatcca gaagaagcaa ctactttcga acaagaatat
    11281 atttttgaac cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt
    11341 ttgatctacg gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca
    11401 atgaaaacag caactgataa tgctgctaat atcattgatg agctgacggt ttcttacaac
    11461 cgtgcaagac aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca
    11521 ctagaatagt attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat
    11581 cggtcccgtt gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc
    11641 attagttgtt tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga
    11701 attaggggac ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg
    11761 aatggaagtc attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg
    11821 tcgcgtattc aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc
    11881 ggaaagaagc gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga
    11941 aattttggaa acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa
    12001 agtcggacta ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca
    12061 taatatcgcc caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg
    12121 tgaaggtaat gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat
    12181 ggtgttcgga caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt
    12241 gacgattgcg gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa
    12301 cattttccgt ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc
    12361 tgcggttggt tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac
    12421 atctacgaaa aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta
    12481 cactgacccg gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg
    12541 taaattaaca gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc
    12601 tttagcacct gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt
    12661 attgcaacga tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc
    12721 cgatcaagaa aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa
    12781 ctttaacgtg gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac
    12841 agtgaaagga ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt
    12901 ccgaagtgtt ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa
    12961 aggggtgccc catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct
    13021 atgatcacca tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc
    13081 ctaaacatgc accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag
    13141 attcagatac ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata
    13201 atgttgtttc aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg
    13261 cggaacgtgc aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata
    13321 cgaacgaatt gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat
    13381 ctaagcactc ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg
    13441 ttatgacaga agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa
    13501 atttttgtga aatctcagct tatttttcga agaagctact tctggaacac cgtatatcgg
    13561 aggttgtgaa atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc
    13621 atattttgcc gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg
    13681 aataagggac tgcgacaaga cttttgtggc tctttgtcaa taaggactga tgagttgtgc
    13741 aaaatcaaat ctgagtcaga atgaaccaca ttctggctca gattttttgt tatcttacat
    13801 tgattaattg attgatcaaa aagattctaa ttctcatgtt ctcaaatgat
//
LOCUS       DAIGUC010000068        13820 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.069, whole genome shotgun sequence.
ACCESSION   DAIGUC010000068 DAIGUC010000000
VERSION     DAIGUC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.069"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..134
                     /locus_tag="NOB46_002372"
     CDS             <1..134
                     /locus_tag="NOB46_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1059281.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            238..2514
                     /locus_tag="NOB46_002373"
     CDS             238..2514
                     /locus_tag="NOB46_002373"
                     /inference="COORDINATES: protein motif:HMM:NF024867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1059282.1"
                     /translation="MSLKLKGIKIDSFRAFERQKYFDCVNPVFNEISNLIVLYAPNGT
                     GKTSFFDAIEWSLTGEISRLNENKNVRDIASQERKYILKNKYSSAEVDSVELAFDDGS
                     FYALTTKRLNGKQTTDYVEGNETKKTVDLTAKELKILRQKNLLTHNQIDAFLRSQSAE
                     GRYDALSNFWDKENVSEDYKNLVLFVNEMNKVLGQQETKMNQLTKEIEKLESNAKIWQ
                     TINQLKENYAKLNGKNSKKDPLLKNQLGLQELYIESNKLKSNNQIKLNQFEEERQQLE
                     NLITMIQEYRQIPQQIEWSEKQVADVNEKLAHLTEIETIEEKKKALFDEKIDLSNHLK
                     RCNFLINHEADFQALEMAEQNSNREINEWINQRKKCEQALITLQKEHQEQEVTLSECQ
                     NKRALRTNQLTEIKELNSYSDVKAKRQLLDHEIKQQKKKKIGLEAKLGKIKLTLTKLF
                     SLLNLDDHQLSQKDYSKDPDYSFLLEQISQLDDIWQERKKLEVDLTQKKKERSSLEDL
                     GSQLEQLKKLGYSIVTDTSSSVCPLCLHDHQEFQHIIQKIEASTADLLPIEQLTKEIS
                     HLEGMIDESTRRLTEVVSGVKQQIQIQITVKETEINQLDQDLLQVTLKLKQQEEAYLT
                     NEKHWYKLNEYSQKYGIDCEKIAEETQKRVKSLQEELVKLTNEYQNIKEKINQNEQLN
                     VKNTHTLKTIELHYQQAKKSLNDLKGNEQYQHYQQEQAFYEALGISVISDFKRQCKRE
                     LEKINEQETKLIAEKNND"
     gene            2661..3350
                     /locus_tag="NOB46_002374"
     CDS             2661..3350
                     /locus_tag="NOB46_002374"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI1059283.1"
                     /translation="MEKNKQKLTTAIYKLNEKNQLLGQLSGLTSDFISETGIETKRSE
                     QAKVKKIYDHLSRKVQELKELKDSKLTEIKKQIKSTFNLYTVNQIFQMIEPHPDFRKI
                     SFKINEANPDKLGLDIMCKRTEDEEDAPILYLSSAQVNILSLSIFLGTALENTDKVNT
                     IFMDDPIQHLDSLNELSFIDLLRILAFKLGTQIIFSTHNRQFFDLCQRKLDANYHNAS
                     FIEMNYTENQL"
     gene            3696..3884
                     /locus_tag="NOB46_002375"
                     /pseudo
     CDS             3696..3884
                     /locus_tag="NOB46_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4139..4870
                     /locus_tag="NOB46_002376"
     CDS             4139..4870
                     /locus_tag="NOB46_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1059284.1"
                     /translation="MGNSFKNKALYHQLVDLLKNQMESNMIPHDKLPSERELTAQYGV
                     SRTTVRLALKELENTGYIYRRHGKGTFVSDIKKNVADLAGTYSFTEQMKSLGRTAETR
                     ILAFEKIEADKFIAKQLNLSLGEVVFKLSRLRIADREPLMIEDTYLPVKFFLSLNDQL
                     LRSKPLYDLFSEDFNQTVRLADEELYASVASKEDAKQLIISEGAPVLHLARQTYNMKN
                     EIIEFTLSVARADQFHYQIRHIRNS"
     gene            4883..6055
                     /locus_tag="NOB46_002377"
     CDS             4883..6055
                     /locus_tag="NOB46_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1059285.1"
                     /translation="MFTVGKEKLDQLGAEITTREIRQQPELWEETLDHYQTVQKELDN
                     FLAIVKEKANGQRTRVIFTGAGTSQYVGDTLVPYLRKNGDRQAFSFESIGTTDIVAEP
                     EEYLIKEDPTLLVSFARSGNSPESLAAVEIANQMVDTIYHLSITCAVEGKLAQISQSD
                     SNSFLFLMPARSNDSGFAMTGSFSCMTLGALLTFDQTVLVKKQQYLKVLNNLGNEVIT
                     RVNEIEKIVQLDFERIVYVGSGSLAGLTREAQLKILELTAGKIATIFDSSMGFRHGPK
                     SFINQKTIMFGFVNNNPYTRDYDLDVLEEVRGDEIASGVFAITQPGQRNFTGDKFEFT
                     TEAELLPDGYLALSYIMVAQIVALLSSIKVNNKPDTPSPTGTVNRVVKGVTIHKYK"
     gene            6078..7085
                     /gene="lacD"
                     /locus_tag="NOB46_002378"
     CDS             6078..7085
                     /gene="lacD"
                     /locus_tag="NOB46_002378"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI1059286.1"
                     /translation="MITLTRGKKAAMDRLSTKDGIISALAIDQRGALKKMIKALNVEL
                     NDEQIERFKELVSSELTPYASSILLDPEYGLPAASARHEDAGLLLAYEKTGYDVTTPG
                     RLPDLLADWSVLRLKEQGADSIKFLLYYDVDEDPEINHQKHVFVERLGSECAEEDLPF
                     YLELLSYDTQISDVHSLEYAKVKPHKVNSMMKEFSKPQYKVDVLKVEVPVNMNFVEGF
                     STDEVAYTEEEAAKYFLEQSQATDLPFIFLSAGVSTKLFQQTLFFAKDSGSTFNGVLC
                     GRATWKNGVKPFIKSGEESARAWLKSEGRENIESLNNVLAQTASSWYDKVQVEKEAAV
                     N"
     gene            7097..8035
                     /locus_tag="NOB46_002379"
     CDS             7097..8035
                     /locus_tag="NOB46_002379"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HCI1059287.1"
                     /translation="MIVTVTMNPSIDISYPLASLNVDTVNRTDQVSKTAGGKGLNVTR
                     VIHDLKGDVLATGVLGGYHGAFIADELKHAGIKQKFTDIKEESRDSIAVLHEGNQTEI
                     LEAGPTVSYEEQQNFLENFKELIKKAKIVTISGSLAKGLPSNFYQTLVQLTEEQSAKV
                     LVDTSGESLHQVLAGKQKPFLIKPNLEELSTLLRHSFSIDRLEEVQEELIQPIFAGIE
                     WIIVSLGKAGALAKHKDCFYRVTLPTIKAVNPVGSGDATVAGFAYGLSQEMDEIELLK
                     FCMATGMANAQEGQTGHVSPVNIQSHIEKITVKKIE"
     gene            complement(8056..8718)
                     /locus_tag="NOB46_002380"
                     /pseudo
     CDS             complement(8056..8718)
                     /locus_tag="NOB46_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370247.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            8869..10647
                     /locus_tag="NOB46_002381"
     CDS             8869..10647
                     /locus_tag="NOB46_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HCI1059288.1"
                     /translation="MNTFEIKEDFLLNGKPFKILSGAIHYFRVDSADWYHSLYNLKAL
                     GFNTVETYVPWNLHEPKKGDFHFEGILDLEHFLSIAEELGLYAIVRPSPYICAEWEFG
                     GFPAWLLNEGTRIRTNETVYLNHVADYYDVLIKKIVPHQLTNGGNILMIQIENEYGSY
                     GEEKDYLRSIRDLMLDRGITVPFFTSDGPWRATLRAGSMIDEDILVTGNFGSKAEENF
                     SSMEAFFNEHGKKWPLMCMEFWDGWFNRWKEPIVQRDAKELAEAIKEVVLRGSINLYM
                     FHGGTNFGFMNGCSARGVIDLPQITSYDYGAPLDEQGNPTEKYYAIQTMIHETFPDIQ
                     QMEPLTKDTMEMKDIPLIDKVSLFSTLDTISQSVKMKYPETMEMLGQNTGYILYRTSI
                     KKDAEHERLRVIDGRDRSQLFLNQKLQATQYQTEIGEDIIVPMPQEDNQLDILIENMG
                     RVNYGHKLLADTQKKGIRTGVMADLHFITDWNQYCLPLESCEKVDFSKEWHPNQPSFY
                     RYEVTLDEVEDSFIDLSKFGKGVVFVNQTNIGRFWEVGPTLSLYIPKSLFKKGNNEIV
                     IFETEGTFQPEIQLVKAPLYKEMKEG"
     gene            10651..11130
                     /locus_tag="NOB46_002382"
     CDS             10651..11130
                     /locus_tag="NOB46_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HCI1059289.1"
                     /translation="MSIIGVRIDGRLIHGQVANLWTTKLNITRIMVVDDEVAKNDIEK
                     SGLKLATPPGVKLSVLPIEKAANNILAGKYDSQRLLIIAREPDRLLKLVELGVPIEEI
                     NVGNMSQTNETRSITKSINVVDQDVEVFNKLQAKGVRLVAQMVPSDKAENFMALLAK"
     gene            11143..12039
                     /locus_tag="NOB46_002383"
     CDS             11143..12039
                     /locus_tag="NOB46_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059290.1"
                     /translation="MDILWWQILLLTLYAGYQILDELQIYSSLSAPVFAGLFAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSVALGMNPEQAIAVIAVP
                     VASLMIQLDILARFANTYFAHRIDKLVEDMNYKGIERNFLMGALSWSLSRMIPVFLAL
                     AFGGGLVEQVVVVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHFPYLILGFT
                     LTALLGTVFTNMQVLGTGVAGAVKNFEGIFNSLPMLAIALVGFSLAAISYKNGQLIPH
                     SPAPKDVTSNDSDEGEIEDDEI"
     gene            12026..12835
                     /locus_tag="NOB46_002384"
     CDS             12026..12835
                     /locus_tag="NOB46_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1059291.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKLYGDNSPELKEMMKTHTQFFNTSNFFNTIVTGIDLAIEEKEGIDGKDTVSGLKA
                     GLMGPFAAIGDSIFAALIPTIFGALAANMAINGNPTGIFIWIIAQIAVMIFRWKQLEF
                     AYREGISLVTTMQHRLTALTDAATLLGVFMVGALVATMINVKLSWAPSIGDVTLNMQN
                     NLDMILPRLLPAGIVAAIYWMLGKKNMTSTKAIFIVLVVCVALSALGVISK"
     gene            12873..13277
                     /locus_tag="NOB46_002385"
     CDS             12873..13277
                     /locus_tag="NOB46_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI1059292.1"
                     /translation="MGKQLVLISHGLFCEELKKSTEMIMGPQESIHTVSLLPSESAED
                     FREKFETVIANLDDFVVLADLMGGTPCNVVSKIILEGQVIDLYAGMNMPMVIDFINSQ
                     LIGTELSLIESATSNICYVNGRIFSDDDDEDE"
BASE COUNT         4859 a         2146 c         2777 g         4038 t
ORIGIN      
        1 aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat
       61 cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt
      121 ctagcttaat ttgacaaatc atagaattaa aaacgatggc taaaaaagag aaaaaagcac
      181 gaatacaaga gtatataaaa catgagctgt caaatcttaa cgtaaaggaa ggaaccgatg
      241 agtcttaaat tgaaagggat aaaaattgat tcgtttcgag catttgaaag gcaaaaatat
      301 tttgattgtg tgaatcctgt ttttaatgaa atatcaaatt tgattgtttt gtatgcgcca
      361 aatggaaccg gaaaaacctc tttttttgat gccatcgaat ggagcttgac tggcgaaatc
      421 agtcgactga atgaaaataa aaatgtccgt gatatcgcct cccaagagcg aaagtatatt
      481 ttaaagaaca aatattcctc agccgaagtg gacagtgtgg aactagcatt tgatgatggc
      541 agtttttatg cattaacgac gaaaaggtta aatggaaagc aaacgacgga ttacgttgaa
      601 gggaatgaga ccaaaaaaac ggttgattta acagcgaaag aattaaagat tttacgacaa
      661 aaaaatttat tgacacacaa tcaaatcgat gcttttttac gatcgcagag tgccgaagga
      721 agatatgatg ctttaagtaa tttttgggat aaagaaaatg tatctgagga ttataaaaat
      781 ctagtcttat tcgtcaatga aatgaataaa gtattaggac aacaagaaac taaaatgaat
      841 cagctaacaa aagagattga aaaactcgaa agtaatgcaa aaatatggca aacaatcaac
      901 cagctgaaag aaaattatgc caagttaaac ggaaagaata gtaaaaaaga tccattgtta
      961 aagaatcaat taggtttaca agaattgtat atcgaatcga acaaattaaa aagcaataat
     1021 caaataaaat tgaaccagtt tgaagaggag cgacaacagc tagaaaattt aatcacaatg
     1081 atccaagagt atcgacaaat accgcagcag atcgaatggt ctgaaaagca ggttgctgat
     1141 gtcaacgaaa agttagccca tttgacagaa attgagacaa tcgaagaaaa aaagaaagca
     1201 ctgtttgacg aaaaaataga cttgagcaac catctcaagc gttgtaactt tcttatcaat
     1261 catgaagcag attttcaggc actagaaatg gctgaacaaa acagtaatag agaaatcaat
     1321 gaatggatta atcaacgaaa aaaatgtgaa caagcattga ttactttaca aaaggagcat
     1381 caagagcaag aagtaacatt aagtgagtgt caaaataaac gagcgttgcg gacgaatcaa
     1441 ttaacagaaa tcaaagaatt aaacagttat tccgatgtta aagcgaaaag acaattactt
     1501 gatcatgaaa tcaaacaaca gaaaaagaaa aaaatagggt tggaagccaa gttaggtaag
     1561 ataaagctaa cgttgacaaa attgttttca ttactaaact tagacgatca tcagttaagc
     1621 caaaaagact attcaaaaga tcctgattat tcatttttgt tggaacagat aagccaactt
     1681 gatgacattt ggcaagaaag aaaaaaattg gaagttgatt taacacaaaa gaagaaggaa
     1741 cgttcctctt tagaagatct gggcagtcag ttagaacagt tgaaaaaatt aggttattct
     1801 atcgtaacgg atacgtcttc gtctgtctgt ccattatgtc tccatgatca tcaagaattt
     1861 caacatatca tccaaaaaat tgaagctagt acggcagatc ttttaccgat tgagcaactg
     1921 acgaaggaaa tcagccactt agaaggaatg atcgatgaat caactaggcg gttaactgag
     1981 gtagtctctg gagtaaaaca acagattcag atacaaataa cggttaagga aactgaaatc
     2041 aaccaacttg accaagatct gttacaagta accttaaaat taaaacaaca agaagaagcg
     2101 tatttaacca atgagaaaca ctggtacaag ttaaatgaat acagccaaaa atatgggatt
     2161 gactgtgaaa aaattgctga agaaacccag aaaagagtaa agtcactaca ggaggaattg
     2221 gtaaaattaa cgaatgagta ccaaaatatc aaagaaaaaa tcaatcaaaa tgaacagctg
     2281 aatgtcaaga atactcatac gctcaaaacg atcgaattac attatcaaca agcgaaaaaa
     2341 agcttaaatg atttaaaagg aaacgaacag tatcaacatt atcagcaaga acaggcgttt
     2401 tatgaagcgc ttggtatttc tgttatctct gattttaaaa ggcaatgtaa acgcgagtta
     2461 gaaaaaatca atgaacaaga aaccaagctt attgccgaaa aaaacaacga ctagaacaag
     2521 taaatgggaa aagtaaaaca gaattagtag aagaacaacg aatccaagca gagcagattc
     2581 ggcagctcgt tgtacggagg aaatatatcg aaaagatatc ttatcaactg tttgaccaag
     2641 taatcattgc accagaagaa ttggaaaaaa ataagcaaaa attgactaca gctatttaca
     2701 aattaaatga aaaaaatcaa ctgttgggtc aactatctgg gcttaccagt gattttatct
     2761 ctgaaacagg tatcgaaacg aaaagaagcg aacaagcaaa agtaaaaaaa atctatgacc
     2821 acttaagtag aaaagtacaa gaactaaaag aattaaaaga cagtaaatta accgagatca
     2881 aaaagcaaat caaaagtaca tttaacttat ataccgtcaa tcagattttt caaatgatcg
     2941 aacctcaccc tgattttcgt aagattagtt ttaaaatcaa tgaagcaaat cccgataaat
     3001 taggactgga tattatgtgc aaacgaacag aggatgaaga ggatgccccg attttatatc
     3061 taagttctgc ccaagtaaat atattgtctt taagtatttt tctaggaacc gctctagaga
     3121 atacagacaa agtgaatacg attttcatgg atgatccaat ccaacactta gatagtctta
     3181 atgaattatc ctttattgat ctattaagaa tccttgcatt taagctagga acacagatca
     3241 tcttttccac ccataaccgc cagttttttg acttatgtca gagaaaatta gatgccaatt
     3301 accataatgc cagttttatc gaaatgaatt atacagagaa tcagttgtaa caaatttagt
     3361 tagtcagaaa aagtgaataa gggagctctt tgatgagagc tgaggttagc tgaaagattc
     3421 agagtataaa acaaaaattg cctacagaag taaataaaga gacgaataga gaatcaatcc
     3481 caacgaataa gggattgatt ctttttttct agattaaata cagataggaa gaatatatag
     3541 attggatgga gagttgtact acctatacga aagcagaagc ttttttaggc tctacacttt
     3601 ttgatattgg cgaaattcgc caacattttt ttatgattta aacggtatag aaaagacatc
     3661 attcactatt tgggggctat ttaaccagag aaaccgaaac ctatacgaca actttgcgaa
     3721 catttagaaa gtttctgaca cagatccgaa atgccctccg ctacaattac tcaaacggat
     3781 tactagaatg tttaaacaag cctatcaaag tatttaaacg aaatttttat catttcaaac
     3841 ggcgaatcat gattcgtcac gataaaactt ttttaagcaa ataaacatac taagattagt
     3901 aggtttctat ttcctgtttt tttcaactgg tatcagattt cagcacttat gactgttatt
     3961 ttcgctagga acaatttctt aaaaatggat agttttatta tttcaataaa ataatcattg
     4021 ctaaatcaac gatttaagac ggttgtagaa tttttttcag attgtttgtt gacaaaaata
     4081 aaaaaaccat cttaccatta gtttgtggtt ataaccagtt taaaagaagg agaaacctat
     4141 gggaaattct tttaaaaaca aagctttgta tcatcagttg gtagatttac ttaaaaatca
     4201 gatggaaagt aacatgatac cccatgataa attaccctct gaacgagaat taactgctca
     4261 atacggagtt agtcgtacaa cggttcgatt agctttgaaa gagttggaaa atacaggtta
     4321 tatttatcgg agacatggaa aaggaacatt tgtatccgat atcaaaaaga acgtagcaga
     4381 tttagcagga acctatagct ttactgaaca aatgaaaagt ttaggtagaa ctgctgagac
     4441 gcggatctta gcttttgaaa aaattgaagc ggacaaattt attgcaaaac aattgaatct
     4501 ttcattagga gaagtagtct tcaaattaag tcgattgcgg atagctgatc gggaaccgct
     4561 tatgatcgaa gatacctatt tgccagtcaa atttttctta tcattaaatg atcagctttt
     4621 aagaagcaaa cctctatatg atcttttttc cgaggatttt aatcagaccg ttcgattggc
     4681 agatgaagag ctatatgcaa gtgttgcctc aaaggaagat gcgaaacagc tgataatctc
     4741 agaaggagca cctgtccttc atttagcacg tcaaacctat aatatgaaaa atgaaattat
     4801 cgaatttact ttaagtgtcg cccgtgcgga tcaatttcat tatcagatcc gccatattcg
     4861 aaatagttag gagaatcgaa acatgtttac agtaggaaaa gaaaaactgg atcagctggg
     4921 tgctgagatc acgactcgcg aaatacgcca acagcctgaa ctttgggaag aaacccttga
     4981 tcactatcaa acagttcaaa aggaattaga taattttctt gcaatagtta aagaaaaggc
     5041 aaatggtcag cgaacacgtg taatcttcac tggtgcagga acatctcaat atgtaggaga
     5101 cacattagtt ccttatttgc gcaagaacgg tgatcgccaa gcatttagct ttgaaagtat
     5161 tggaacgact gatattgtcg cagaacctga agaatattta attaaagaag acccaacttt
     5221 acttgtatca tttgcgagga gtggaaacag tcctgaaagc ttggcagcag ttgaaattgc
     5281 aaatcagatg gttgatacga tctatcattt atcaattacg tgtgctgtag aaggaaaact
     5341 agctcaaatt agtcaatccg attccaatag ttttttattc ttgatgccag cacgttccaa
     5401 tgatagtggc tttgctatga ctggtagctt ttcctgcatg actttaggag ctttgttgac
     5461 attcgatcaa acagtattag tgaagaaaca acaatacctg aaggttttaa ataatttagg
     5521 aaatgaagta attacccgag taaatgaaat tgaaaaaatc gttcagcttg attttgaacg
     5581 cattgtttat gttggttcag gaagtctagc tggattaaca agggaagcgc aattgaagat
     5641 tctggaattg acagccggaa aaattgctac catctttgat tcatcaatgg gctttcgcca
     5701 tggtccaaag tcgtttatta atcaaaaaac aatcatgttc ggttttgtta ataataatcc
     5761 ttacacgcgt gattacgact tggatgtctt agaagaagtg cgtggagatg aaatcgcttc
     5821 cggagtgttc gccattactc aaccagggca acggaatttc actggcgata aattcgagtt
     5881 tacaactgag gccgaattac tgccagatgg ctatttagca ctaagctata tcatggttgc
     5941 ccaaatagtc gctttgttat catcgattaa agtgaataat aaaccagata caccgtcacc
     6001 aacaggaaca gttaaccgag ttgtaaaagg tgtaacgatt cacaaatata agtaaaaata
     6061 aactgggagg aagaaccatg attacattaa ccagaggaaa aaaagcagca atggatcgtt
     6121 tatcgacaaa agatggtatt atcagtgcct tagcgattga tcaacgcgga gcattaaaaa
     6181 aaatgatcaa agccttaaat gtagaattaa atgatgaaca gattgagcgt ttcaaggagt
     6241 tagtttctag tgaattaacc ccttatgcat cttctatttt attggaccca gaatatggtc
     6301 ttcctgctgc aagtgcacga catgaagatg ctggtttgtt gttggcctat gaaaaaaccg
     6361 gctatgatgt aacaacaccg ggacgcttgc ctgatttatt agcagattgg tcagttttac
     6421 gattaaaaga gcaaggagcc gattcgatta agtttctact ttattatgac gtagatgaag
     6481 atccggaaat caatcatcag aagcatgtct tcgtagaacg tttaggtagc gagtgtgccg
     6541 aagaagattt gccattctat ttagaattgc tatcatatga tacccaaatt tcagatgttc
     6601 attcacttga atatgccaaa gtaaaaccgc ataaagtcaa tagcatgatg aaggaatttt
     6661 cgaaaccaca gtacaaagta gatgttttaa aggtagaagt tcctgtcaat atgaattttg
     6721 tagagggttt cagtacagat gaagtagcgt ataccgaaga ggaggcggca aagtacttct
     6781 tggaacaaag tcaagcgaca gatttgcctt ttattttctt gagtgccggt gtttctacga
     6841 agctattcca acaaacattg ttttttgcta aagattcagg ttcgaccttt aatggtgtgc
     6901 tttgtggtag agctacttgg aaaaatggtg tgaagccgtt tatcaaatct ggtgaagaat
     6961 ctgctcgtgc ctggctgaaa agtgaaggtc gtgaaaatat cgaaagcttg aacaacgttt
     7021 tggcacaaac agccagttct tggtatgaca aagtccaagt tgaaaaagaa gcagctgtga
     7081 actaggagga gagctcgtga tagtaactgt aacgatgaac ccgtcaattg atatttccta
     7141 tccgcttgct tccttgaatg tggatactgt caatcgaaca gatcaagtta gtaaaacagc
     7201 aggtggaaaa ggacttaatg taacccgagt aatccatgat ctaaaggggg atgtactcgc
     7261 tacaggagtt ctcggtgggt atcatggggc gtttattgca gatgaattaa agcatgccgg
     7321 tattaagcag aaatttacag atatcaaaga agaaagccgg gattcaatcg ctgttttgca
     7381 tgaaggaaat caaactgaga ttttggaagc gggaccaaca gtttcctatg aagaacagca
     7441 gaatttccta gaaaacttca aggagctaat aaaaaaagca aagattgtca caatctcagg
     7501 tagtcttgca aaaggattgc catcaaattt ttaccaaacg ttggtccaat tgacagaaga
     7561 gcagtccgca aaggttcttg tcgacacctc tggggaaagc ttgcatcagg ttttagctgg
     7621 caaacagaag ccatttttaa tcaaaccaaa tcttgaggaa ttatcgacac tactgagaca
     7681 ttcattttcg attgatcgat tagaagaagt ccaggaagaa ttgattcaac ctatcttcgc
     7741 aggtattgaa tggatcattg tttctctagg aaaagctgga gctctcgcaa aacataaaga
     7801 ttgtttttat cgagttacgc tccctacgat aaaagcagtc aacccagttg gttcaggaga
     7861 tgctacagtc gctggatttg cctacggcct atcacaagaa atggatgaaa tagaactttt
     7921 gaagttttgt atggctactg gtatggctaa tgcacaagaa ggacaaacag gtcatgtttc
     7981 accggtgaat attcaatcgc atattgaaaa aataactgta aaaaagattg agtgaaaaaa
     8041 tcgatctaga taaaatcaat gattttttga gaccaactca atttggtaga agttccattt
     8101 ttgtaggatt caacgtactc cagtagttgt tgtgaatctc tacgtttcgt cactcggact
     8161 tgcagaacgg tcgtttcatc ggtaagaatc tttaatgatt tcgcaacatt taaaggagtt
     8221 ggaaatataa ttttatttgt ttccgtaaaa tcttcctcat tcatgtggat attgtagtct
     8281 tgtttaaagc gctgacagct ggaattgtaa taacacaatt cttgacaatt aggatccaca
     8341 tattgttcgg gcaaataagt ttgctgatag atatatgcag ttttttagtt tttcgtaaat
     8401 gtctgatgta atcataaaat gctaaggctg gcagtttaag cttgtttaaa tagtgtggat
     8461 cattccctcg aacgattgat aaaacttgga cttgatcatt actgatagtg aataattcaa
     8521 tgtcagaaaa ctagaacagt ttttctttac gtgaaacaaa tgagtcacga ccttgatgac
     8581 gaattatgaa tccatccttt attcattcag ggagcgaatg actgtaatag agcttacgtt
     8641 aaatatttgt attaattctg cttctgtata aagtttattg ccattttggg atgtctaaat
     8701 taacccttca aacaacatca aagaattaaa cttttcgtta gagtctttgg ttttgtatgt
     8761 ataatttgat tttaacacgt tctgttatgt tggatatggt tgaatttcta tttcaaatta
     8821 tttaatatat caatatattg aaaacgcttt tatttaagga gggagctttt gaacacattt
     8881 gagattaaag aagattttct tctaaacggt aagcccttta agatactctc aggagctatc
     8941 cactatttta gagtggattc agccgattgg tatcactcgt tatataatct gaaagcattg
     9001 ggatttaata cagttgaaac ttatgtacca tggaacctac atgaacctaa aaaaggagat
     9061 ttccattttg agggaatttt ggacttagaa cattttttgt ccattgctga ggaattagga
     9121 ctatacgcga ttgttagacc atctccatat atttgtgcag aatgggagtt tggtggtttt
     9181 cctgcttggt tacttaatga gggaactcgg atccgaacaa atgaaaccgt ttatttgaac
     9241 catgtggcag attattatga tgttttaata aaaaaaatcg tgccgcatca gctgacaaat
     9301 ggtggaaata ttttaatgat tcaaattgag aatgaatacg gttcttatgg agaagaaaaa
     9361 gactatttac gttcgatacg tgatttaatg ttggacagag gaataacagt gccatttttc
     9421 acttcggatg gaccatggcg tgcgacactc agagcaggca gcatgattga tgaagatatt
     9481 ttagttactg gaaattttgg ttcaaaggct gaagaaaatt tttcttcaat ggaagctttc
     9541 ttcaatgagc atgggaaaaa atggccttta atgtgtatgg aattttggga tggttggttt
     9601 aatcgttgga aggaaccgat tgtacaacgt gatgcaaaag aattagctga ggcaatcaaa
     9661 gaggtcgtgc tgagaggaag tattaacctg tatatgttcc atggaggaac aaattttgga
     9721 tttatgaatg gttgctcagc tagaggagtg attgatttgc cacagattac ttcttatgat
     9781 tacggagcac ccttagacga gcaaggaaat ccaaccgaaa aatattatgc aatccagaca
     9841 atgattcatg aaacgttccc tgatatccaa caaatggaac ctttgacaaa agacacaatg
     9901 gaaatgaaag atattccatt aattgataaa gtcagtttat tttcaacatt agatacaatt
     9961 agtcaatcag taaaaatgaa atatccagaa acgatggaaa tgttaggaca aaatacaggt
    10021 tatattctgt atcgcacctc aataaaaaaa gatgcagaac atgaaagact gagagtaatc
    10081 gatggaagag accgtagcca actattttta aatcaaaaac tgcaagctac acaatatcag
    10141 acagaaattg gtgaagatat cattgttcca atgcctcagg aagacaatca attagatatt
    10201 ctaattgaaa acatggggcg cgttaattat ggtcataaat tattagccga tacacaaaaa
    10261 aagggaattc gtacaggggt catggctgat ctacatttta tcactgattg gaatcagtat
    10321 tgtttaccac tagagtcatg tgagaaagtt gatttttcaa aggaatggca tcctaaccag
    10381 ccaagttttt atcgctatga agtaacactt gatgaagtgg aggatagctt cattgatcta
    10441 tcaaaatttg ggaaaggtgt cgtatttgtt aatcagacca atattggacg tttttgggaa
    10501 gttgggccaa cactttcgct atatattccg aaaagcttat ttaaaaaagg aaacaatgaa
    10561 atagtgattt ttgaaacaga aggaactttc caaccagaga tccaattagt aaaagcacca
    10621 ctatataaag aaatgaaaga aggataaaca atgagtatta tcggagtaag aattgatgga
    10681 cgtttaattc atggacaagt agccaactta tggacaacca agttgaacat cacacggatt
    10741 atggttgtag atgatgaagt tgcaaaaaat gatattgaaa aaagtggatt aaagctggca
    10801 actccaccag gagttaaatt aagtgtattg ccgattgaaa aagctgctaa taatatttta
    10861 gcaggaaaat atgattctca acgattattg attattgctc gggagccgga tcgtttattg
    10921 aagttggtag aattaggagt cccaattgaa gaaattaatg ttgggaatat gtcacagaca
    10981 aatgaaacac ggtccattac taaatcaatc aatgtggttg atcaagatgt agaagtattt
    11041 aacaaattac aggctaaagg tgttcgctta gtagcgcaga tggttccaag tgataaagca
    11101 gaaaatttta tggctttatt agcgaaatag gaggataaat aaatggatat cttatggtgg
    11161 cagatcttat tattaacatt atacgcaggg tatcaaattt tagatgagtt acaaatttat
    11221 tcatcgttga gtgcacccgt ttttgccgga ttatttgctg gtctagtgat gggagatcta
    11281 aaagcaggac ttattattgg tggtagtatg caattgactg tacttggtgt tggtaccttt
    11341 gggggggcat caaaaattga tgccaactct ggaacgattt tagcgacagc tttctcagta
    11401 gcgctaggaa tgaacccaga gcaagcaatt gccgtaattg cggtaccagt agctagcttg
    11461 atgattcaat tagatatatt agcccgtttt gcgaatacgt attttgcgca tcgcattgat
    11521 aaattagttg aagatatgaa ctataaaggg atcgaacgta atttcttaat gggagccctc
    11581 tcttggtcac tttctcgtat gattcccgtt tttctagcat tagcatttgg aggaggacta
    11641 gtagaacaag tggtagtcgt gctaaatggt gatttgaagt ggttaggcga tggattatca
    11701 gtagctggag cagttttacc agctgtcggt tttgctattc tactacgtta cttgccagtt
    11761 aaaaagcatt tcccttacct aattttagga tttacattaa cggcattact aggaaccgtc
    11821 tttactaaca tgcaggtttt aggaacgggt gttgcaggag ctgtgaagaa tttcgaagga
    11881 atatttaatt cacttccaat gttagcaatt gcactagttg gattttcttt agcagccatc
    11941 agttacaaaa atggacagct gataccacat tcgccagccc ctaaagatgt tacatcgaat
    12001 gattcagatg aaggagagat tgaagatgac gaaatctaat tataagttaa cgaaggaaga
    12061 ctttaagcag atcaatcgca gaagcttgtt tactttccaa ttaggctgga actatgaacg
    12121 gatgcaagga tcaggctatc tttatacaat tctgccgcaa ttacgcaagc tttatggtga
    12181 taattctcct gaattaaaag aaatgatgaa aactcataca caattcttta atacatcaaa
    12241 cttcttcaat actatcgtta ccgggattga cttggctatt gaggaaaagg aaggtattga
    12301 tggtaaagac actgtctcag gtttaaaagc tgggttgatg gggccttttg cagcaattgg
    12361 tgattcgatt ttcgcagcgt taattccaac aatttttgga gccttagcag ccaatatggc
    12421 aattaatggc aacccaactg gaatttttat ttggattatc gcacaaatcg ctgttatgat
    12481 tttccgttgg aaacaattag aatttgctta tcgtgaagga atctctttag ttaccacgat
    12541 gcaacatcgc ttaactgcct tgacagatgc tgcaactttg ttaggggtct tcatggttgg
    12601 agcgttggtc gctaccatga ttaatgtaaa attgtcttgg gcaccgagta ttggtgatgt
    12661 gacgttaaac atgcaaaata acctggatat gattttacca cgattattac cagccggtat
    12721 cgttgcagca atttattgga tgcttggcaa aaagaatatg acttctacta aggcaatttt
    12781 catagtatta gtggtttgtg tagcattatc agctttaggc gtgatttcaa aataagtcag
    12841 gctgattcca attagtgatg aggagtggtt caatgggaaa acaattagtt ttaattagtc
    12901 atggactttt ctgtgaagaa ttgaaaaaaa gtacagaaat gataatgggg cctcaggaaa
    12961 gtattcacac agtaagcctt cttccttctg aatcagcgga agattttcgt gaaaagtttg
    13021 aaacagtaat tgccaattta gatgatttcg tagtattagc agatttaatg ggtggcactc
    13081 cgtgtaatgt agtttcaaaa ataattctcg agggtcaagt aattgactta tacgcaggca
    13141 tgaacatgcc aatggtgatt gacttcatta acagtcaatt aattggaaca gaactttcat
    13201 taatcgaatc tgctacaagt aacatttgtt atgtgaatgg acggattttc agtgatgacg
    13261 atgatgaaga tgagtaagat aaaatatatg agtgatgaag ccaaagaaat atttctctga
    13321 tcatactata gataaaagac atttcaaact tgtaatttga gtttggaatg tctttttatc
    13381 tagttttgtt caaaattttg gacaaaaaag agaccctttg tcaaatgatg ttggtaaaga
    13441 gaaattctag aatgattggt gaaagattga gaaaaaaatg ttcagcatca aggaataaga
    13501 aggaatttcc gaaatttgac aagaaacata aatacttttt tttggtgttg attattatct
    13561 acttggtgtg tctcaaattt tttataaatt tcagcgaatt tttgaagatg ccgcttttgt
    13621 ctcattctcc atttttttat tttatgatta acctcataaa aaagtgggac attaattaga
    13681 ttttttctga ttaatatccc agactcgtct acagactgag aacttggaag ggatacttcc
    13741 aggacttttt taaacggttg actcaatggc ttctttatac ttttcaaaaa gggggataat
    13801 ttgcgtgcgc ttttttatgt
//
LOCUS       DAIGUC010000069        13351 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.070, whole genome shotgun sequence.
ACCESSION   DAIGUC010000069 DAIGUC010000000
VERSION     DAIGUC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.070"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(45..1364)
                     /locus_tag="NOB46_002386"
     CDS             complement(45..1364)
                     /locus_tag="NOB46_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1059293.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="NOB46_002387"
     CDS             complement(1361..2014)
                     /locus_tag="NOB46_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1059294.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="NOB46_002388"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="NOB46_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="NOB46_002389"
     CDS             complement(2724..3440)
                     /locus_tag="NOB46_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCI1059295.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3564..3749)
                     /locus_tag="NOB46_002390"
     CDS             complement(3564..3749)
                     /locus_tag="NOB46_002390"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059296.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3976..5249
                     /locus_tag="NOB46_002391"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="NOB46_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="NOB46_002392"
     CDS             complement(5356..6387)
                     /locus_tag="NOB46_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059297.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="NOB46_002393"
     CDS             complement(6394..7224)
                     /locus_tag="NOB46_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1059298.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="NOB46_002394"
     CDS             complement(7221..8036)
                     /locus_tag="NOB46_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI1059299.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="NOB46_002395"
     CDS             complement(8033..8857)
                     /locus_tag="NOB46_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HCI1059300.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="NOB46_002396"
     CDS             complement(8847..9947)
                     /locus_tag="NOB46_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI1059301.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="NOB46_002397"
     CDS             10125..10910
                     /locus_tag="NOB46_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HCI1059302.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="NOB46_002398"
     CDS             10943..11326
                     /locus_tag="NOB46_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI1059303.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="NOB46_002399"
     CDS             11402..11533
                     /locus_tag="NOB46_002399"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1059304.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="NOB46_002400"
     CDS             11502..11738
                     /locus_tag="NOB46_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1059305.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="NOB46_002401"
     CDS             complement(11816..12787)
                     /locus_tag="NOB46_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCI1059306.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4057 a         2914 c         2307 g         4073 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttatccag a
//
LOCUS       DAIGUC010000070        12964 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.071, whole genome shotgun sequence.
ACCESSION   DAIGUC010000070 DAIGUC010000000
VERSION     DAIGUC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.071"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..1177)
                     /gene="iadA"
                     /locus_tag="NOB46_002402"
     CDS             complement(<1..1177)
                     /gene="iadA"
                     /locus_tag="NOB46_002402"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCI1059307.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     "
     gene            complement(1334..3073)
                     /gene="yfcC"
                     /locus_tag="NOB46_002403"
     CDS             complement(1334..3073)
                     /gene="yfcC"
                     /locus_tag="NOB46_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCI1059308.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(3846..4460)
                     /locus_tag="NOB46_002404"
     CDS             complement(3846..4460)
                     /locus_tag="NOB46_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1059309.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(5066..5443)
                     /locus_tag="NOB46_002405"
     CDS             complement(5066..5443)
                     /locus_tag="NOB46_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059310.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(5743..6624)
                     /gene="galU"
                     /locus_tag="NOB46_002406"
     CDS             complement(5743..6624)
                     /gene="galU"
                     /locus_tag="NOB46_002406"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI1059311.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(6667..7686)
                     /locus_tag="NOB46_002407"
     CDS             complement(6667..7686)
                     /locus_tag="NOB46_002407"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI1059312.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(8319..9323)
                     /locus_tag="NOB46_002408"
     CDS             complement(8319..9323)
                     /locus_tag="NOB46_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1059313.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(9336..10385)
                     /locus_tag="NOB46_002409"
     CDS             complement(9336..10385)
                     /locus_tag="NOB46_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1059314.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(10402..11223)
                     /locus_tag="NOB46_002410"
     CDS             complement(10402..11223)
                     /locus_tag="NOB46_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1059315.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(11210..11989)
                     /locus_tag="NOB46_002411"
     CDS             complement(11210..11989)
                     /locus_tag="NOB46_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059316.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(12006..12476)
                     /locus_tag="NOB46_002412"
     CDS             complement(12006..12476)
                     /locus_tag="NOB46_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1059317.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(12488..12907)
                     /locus_tag="NOB46_002413"
     CDS             complement(12488..12907)
                     /locus_tag="NOB46_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCI1059318.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
BASE COUNT         3804 a         2827 c         2075 g         4258 t
ORIGIN      
        1 ttttttcgaa agtcccccat actttgactt ctttttcttg gaccattatt tctcctttag
       61 cgataactgt atcaatatca agcgtttctt tatccaagat acacagatct gcatcagcac
      121 caatttcgat ttttcctttt ttatccaatt tcaatatacg tgctggatta ctggttatag
      181 ctcgtaaggc gatttccaaa gggatacttt ctttttgcac agcttctttg atccctacta
      241 gcaatgcctt ggcacttcct actcctaacc ctaggaaatg attgttttca tcaaaataag
      301 gcaagcttcc ttgtccatct gaggtcatcg tgaaattatc taaagaaaca tcttcctcga
      361 tcaatcgttt cagtgctttg ctgaagcgaa cttcaccatc tgtcttctcc caaaaatcag
      421 gatcttcgct agcagtgaag tcaatcgtgc caccacgttt ggcaaatgcc acgcaagctt
      481 caaataattc tggtgtgcga tttgcatgag taggcaaaaa ttgtgtgatc ggaatttctg
      541 tttcttctac gattcgtgtc aatagctcta gctttctttt tcctccgcct aagtggacat
      601 tgatgatccc agcttttccg gataacatgc ctcctacacg agcatctgct actgcacgag
      661 cgaactcttc aaaacttggc tgagaagaac ggtgatcgga tactgcgatt tctccgattc
      721 cgataatttt atcaattgtc aaaaagtctt tgatgataga atctgttact gtttttaccg
      781 gcaatcggta cgaaccttcg tatacataag tggagattcc ttctgcttcc agacctttcg
      841 ctttgctgat caacgcagtc atatctctac cttctccgtc tgttcccaaa caaccgacaa
      901 ctgtcgttac accagctgta gtcaattggc tcaatgtgac ttctggcgtt cgattttgat
      961 aaccgccttc tcctcctcca cctaaaatat ggaaatgaca gtcaatgaaa cccggggtta
     1021 gtacttttcc ctcacctgaa agttcttcta cttccactcc ttcgtagccg ccttctagct
     1081 gttcttctac agccaaaatc ttcccaccgg caatcagtac atccattttt cctaagtaat
     1141 ctggtgcaaa cacttcaatt tgtcgaatga ttttcataca tttttcctct ttctttaagt
     1201 ataactgatg ataggatctt aaaaaataat ccaaacgata ggatctttac tcctttgatt
     1261 ttaccgtaaa atgacggttc ttggagtcct tatctactgt ttggattact tttttattta
     1321 caggtctcca gtactactgc agacctattg caatggcaat catgatgaaa atagttccta
     1381 aaacaaacag gaatccttgc atcttgattt ggaatcttgc ccattttgcc cattcgatcc
     1441 gtgcaacacc tagcacacca atcaagctgg ctgatacggg tgtaaaagcg tccataaaac
     1501 ctgaaccaag ctgataagca agaactgcta cttgtctgga tacacctact aaatctgcca
     1561 gtggagccat gattggcata gtcaaagctg cttgtcctga atttgatgta acaaccaagt
     1621 tgaacaaact ttggaagatg tacatcgccc aagcaccaat gacagctgga acaccggtca
     1681 acgccgtccc gatcccatgc aaaatcgtat tcaaagctga aggaacagat gcatcagatc
     1741 ctcccaagac aagaagaatc cctttggcca tacctactac gattgctgta ccagctaaat
     1801 cagctgcacc agattggaaa gaagaagcga tgtcattgac tttcattcca tctaatttga
     1861 aaagaacagc aatgattcca gcaactaatc ccatcacaaa gaattgagaa gcgatttctg
     1921 gaatgtaata gcctttttga gtcacgcccc aaacgatcca gacaaggaca actaacatct
     1981 ctaataagat caatttatgc ccaagcatga attttttatt ttcatcagat gtctttttga
     2041 tatgagaacg gaaataatca tctgatttgt aagtcaacga actttctggt tttttacgga
     2101 ttttttctgc atatatcatc atataaccag cggctaatgc agtaacaact acccacataa
     2161 tcaatcggaa tgtcgcacca gacaacacgg ggattccagc aatcccttga gccaccgcta
     2221 cgctaaacgg gctcatccaa gaggtcgcat ttccgacttg agatgcgaca taagtcacgg
     2281 ttactgctac gatcgagtca tatcctaacg caatgacaaa tggaaccatc accattgaga
     2341 atggaattac ctcttctgcc atcccgaatg tagcgccacc gaatgaaaaa gcaaagaata
     2401 atagcggtaa agctaaacgc tccagtccct tagttttact gataaacgca tagatacctg
     2461 cgtcgatcgc tccggtacgc ataataatac caaaagcacc tccaacaaca aggatcaatg
     2521 cagcgatccc tacagcagat ccatacttat ctccagatac tagtccttca aaaacaaaat
     2581 ttaagaaacc aaagccgcca aaatcatctg ttccccatat tttggctgtt ttatgcaatt
     2641 ttttagaagt atcatagata ttttcgccgt actgatcgta aagcacatca tctgtcaagg
     2701 agatttcatc tagtttttcc tgcgtaagat ttttttctcc gtcagcaatg actttttcca
     2761 atcctttttc cggaacatcc agtttttcac gttctgctgg atgatcttgc agttcttcta
     2821 attgatcaaa cacatacgac ttatccagct cgtaagcata acggaaggaa tcttgacgta
     2881 aaacagtacg agtacttgtt tcgccatttg catctttgta ttcaatatct tgcgtgctga
     2941 actttcctgc tggaacgaca aaagtcagta tccatgcaaa gatgactaca ccaaaaataa
     3001 tgacatacgt atggggtgtc gataatttag tgaagtcgcg tttcggtttt cctgaagaat
     3061 ttgttttctt caaatttatt tcttcctttc ttttttcagt aattttgatg aataaaaaat
     3121 ggataatcaa atgaattata cagtaaaaat gacatttcca catgaataat ttattagaaa
     3181 atcacttttt tctattttgt tttttttctc ctatgtatga ttattttttt ctctttccat
     3241 ttatattaag tattttattt ctctgttttt ccttaaaatt ctttttttat ttttagatta
     3301 gagaaaatct cgtcctgttt ttttcatttt acaatcattg aaaaattgaa tttcattgca
     3361 aaaaaaataa taaacactta taaatatcca ttatctatcc ttcaattttt gtgtatttta
     3421 tttctattag aaaaaggtat cctgttggac aattttgtta tatcaggtaa acttcattgc
     3481 aataatgata acaaatgtac tataattact ttgtaaagag ttttggggaa gactctttca
     3541 tcaacgtgta ttaagagaca agaaagaatc catatggatt ctttcttgtc tctttttcca
     3601 ctacttttta tttttctgac actacatatt cttataactc atttctcata actgtgaaac
     3661 aacttataaa aataacaaac tttaaacaaa acaagcttaa aatcaaagat gatccatctt
     3721 aaaataacta aaacaaaaaa agtagtcgtt gttaatcctc attaataatc gttttctttt
     3781 tttcaaacgc tccattttta tgtggaacat tattttttta aggaactttg tcaacatgtg
     3841 gataactatt ttccacttgt gtcctggact agctgttttg ctgtaaaata caaaacttgc
     3901 tgcagcaaaa agatcgttgc aagagaggct gttccgcaga tcgctggatc tagatttggc
     3961 aaagtcaaga ctgcatcatg taaattggcg tggttgtcca aaaccaaatc agcaaattca
     4021 aataatcgca aaccactgct atgttgcgat ttgatacttc gtgacaaatc aaatccagta
     4081 acaatgatta atggatgacc attttctttg atccactgag ctagttcgat gattgccggg
     4141 tttcttcctt cattcgaaag aagaagaaaa atgtcttctg atttgacaga aagctgatca
     4201 ataattgcct gtcctgcacc ttctagcgtt tcatagacac ctccggctgg attttcaatc
     4261 aatatacttg gtacaagatc cggggtttga tcccaaaatt caaatgctac accacttagt
     4321 gtgcggctag catatatctg caatctacca ccttgattaa tttgtttcgc gatccaagtg
     4381 ccagcttgaa gcatcagcgg ctcttctatc cttaatttct cttccaattg gtgataatag
     4441 tcaaaataac ataaactcat ttatctctcc cgcctagcta tacttgacat gaatagaaac
     4501 agctgcctaa tctaaggaag tacataaaaa aacagtagtt agacagtaac acatgtggtc
     4561 tttgctgttt caaacacaaa aaaggcattg aacgaatacg cccaatacct tgacatagca
     4621 aataaaacaa cgtgcagacc atggaaaata tctacatagg ggtagaattt tcaccctaga
     4681 ttaggtacaa taaattaggt cgatgcactg cattgactat ggcaaaatga tcggtcaggg
     4741 tgtatgtgtg tgactggtca ttccctgatt cttagcgcca actaagggtc agggagcctt
     4801 tttttattca gctgtttcta tctgaattta ttgtaagtaa tctcttatcc aagtgcaagc
     4861 aagaaaatac aaaaaaacat tggtatgatt tatatatata taaataacat aaaaaaagga
     4921 atggcttatc ccgatacaac aagcattcct ttaaaaaaga ttcttttata taagtgaaaa
     4981 aagctttttt ccaccaatta aataaatctc tcatctcaat agtttatcca ttattttatc
     5041 tttttttgcg tatacctact aaatattacc gtcttcttct cgttcttcta ctttgttcga
     5101 gagaatctgt actagaaaaa gtagttgtat gtctaccttt tctgcctatc cgagactttc
     5161 ttttcatata tgggatataa atgattagat acagtacagc aaaaaataaa gcaaatacgc
     5221 aagcttccca actacctaac gccaattcaa ccatcaaggt agcaacccca acggatgctg
     5281 cataccagat aaaaatcaga aacgtttctt tttttctgac catgcgaaac atgataaata
     5341 gactaataag caatagtggc aacacaaata tccaattgct tccttccatc agccacttga
     5401 gtatatcaag cagcgactgt gcaacagcga ctaattttcc catagtgaac acacaccttt
     5461 ttttataatt aaaaaattcg cctttttatt ctactatgaa tcttctggct tggctttcat
     5521 ttctcttatg taatcatttt cttttataca acttaaaaaa aaattaaacc attagcataa
     5581 tattttctga atctattcac gaaagtcttt ttctatcttt cgttttccac gactcaactg
     5641 atctagagtc aaaaaactaa aacgacagtt gcgcaaatga cgcacaagct gccgctttaa
     5701 taacaaatag cctttcattc tcagcaggcc acttatttcc agttaacttt ctgttcttag
     5761 ctttttactc aactggataa tatatgcact taatgaagtc ccaatttccg aatgttgaag
     5821 tccatattca atatttgtct tcatatatcc taacttatcg cctacgtcgt atctttttcc
     5881 tttaaactct ctcgcataga ccgcctctgt ctggttaaga gtctgaagtg catccgttag
     5941 ctgtatctcg tttcctgctc ctggttcttg agtttctaat atctcaaata ttttaggagt
     6001 cagtagataa cgtccgataa tggctaaatt acttggtgct tttcccattt caggtttttc
     6061 tacaaaccct tttactctgc aacgaccctt ttcgctatct gttttaggat caataattcc
     6121 gtatttagat gtttcatttt ctggtacacg catgacggca acagcggaag cttgtgtttc
     6181 ttcataatcc atcatcaatt gttgagtcaa tgggatatca tctttcatca aatcatcccc
     6241 cagcatgacg acaaacggtt catttcctat aaatgctttt gcttgaagca cggcatcccc
     6301 cagtcctctt ggatgagatt gacggatgaa gtgaagattg acttgagtcg tttcttcaac
     6361 taaagcgagt aattctgttt tttccttttc ccgcaaattg ttttccaatt cgatatttgc
     6421 atcaaagtga tcttcaatgg gtcttttttc ttttcccgtt acgatcaaga tgtcttcgat
     6481 tcccgaatcc aatgcttctt ccacaataaa ctggatcgtt ggtttatcca cgattggaag
     6541 catttctttt gccatggctt ttgttgccgg caaaaaacgt gttcctagcc cagcggcagg
     6601 aatgactgct tttttgacct tcacttgctg ttcctcctaa acgacgatta actattgatc
     6661 atctatttaa cgaagagaaa attcattctc catttttccg tcacgtaaca tgatttcttt
     6721 tgctgctttt ttgatatctt ctccattata caaaacatta tagattgttt gagtaattgg
     6781 catctcaaca cctagctgtt gagctagctc tactgctgct tttgtcgttg ccacaccctc
     6841 aacgaccatt cccatgtttt ctagaacttc ttccagctta tgtccctgtc ctaacaagtt
     6901 accggcacgc caattgcgag aatgaacact tgtacaagta acgatcaagt cccccacacc
     6961 actcaaaccg ataaatgtca gaggattggc acccatcgcg acaccaagac ggctgatttc
     7021 tgccaatcct cgagtcatga ttgctgcttt tgcatcatct ccgaatccta atccatggat
     7081 agcgccggca ccaattgcaa tgatattttt cagtgctgca ccagtttcta cgccaatcac
     7141 atcattattt gtataaatcc tgaaataatc attcatgaac agtttttgta cataggctgc
     7201 tgctttttga tcaatacttg cagctgtaat tgttgtgata tcatgtactg ccacttcctc
     7261 agcatggcta ggaccagata atacaacaat tgcctgtctt ttttcttctg gaatttcttc
     7321 agccaaaact tctgagattc gtttatgcgt atcttgttct agtcctttac ttgcatgtat
     7381 aatgattggc ttagtattca ttttaccaat aagttcctgt gcgactgaac gaatcgcttt
     7441 tgttggaaca acaaataaaa tagcatctgc gttatccact gcttctgcca attctttata
     7501 tccgataatc gattctggga tcgtcaaatc aggtaaaaaa tgctgatttg tatgatactt
     7561 attgatttca tcaatctgtt caggtacatt tccccaaata cggacatcat gcccgttttc
     7621 tgccaatgtt tgtgctaaag cagtgcccca agatccagga ccaagaactg cgattttttg
     7681 tttcatggat attcctccaa ataaataatt gataatttcc attatagtat acatttctta
     7741 aagttgggac taatttccat tgtttttaag tgtttgttta cttcttttat cgtttttact
     7801 tgaaataatc aatgatatgt tacaatagtc tacattttat ttttacactc gttatgcttt
     7861 gcttgttcct aagaggaagc agttttgaca atgttactac cagcattact attaggaggt
     7921 taggaaactt ctcctagtga gtattgattt aaaatacata agagacagat tgaacatttc
     7981 taaatctgtc aggtcctgca acggacagat tgtctctgtt gacggttgac ataggaactt
     8041 ttgttttagt caacattctg gatacaaaac gctatgtaaa ctggcgcaac tcgttgtact
     8101 tggactttta ctacggatcc atgcaacaac taaatagtac tattgcataa caaaaaatgg
     8161 ttggcaccca catgtcccat taaacagatt ataagttgaa ctgtagataa tgcaaaaaat
     8221 gtgttttata acgtaattga tgccaatatt ttaaaaaaat aaagggagca gttatcgctg
     8281 ctctctttat tttttatatt ctttttatcc agtctatcct aataatcaaa ctgacgatag
     8341 tagcggcgta tctctaatgg atggcagttc aactgctcca catgagcatc gatgcgttgt
     8401 gtcactacat gcatcaataa gaaagacaaa acacgtccgc gatatttttc actgatacct
     8461 tctactggat agtcttttgt gtctatcaat gtataattgc tgcaaatttt tggcaaaagt
     8521 ttagccacac gttcagataa cactctctgt tcatcttcgc ctaaaaataa tgtgactggg
     8581 gttgtttctt ctacgatctc taacgtcccg tgaagaaact cggcagcatg gatagatttc
     8641 gatggaagcc agctttgttc ttcccagtaa cacatggcat atgaataaac agctccccat
     8701 tgattccctg ctccaataaa ataatgcata ctatcacgtc gatgtttttc tgcaaatgat
     8761 aagccaaatg catctgcttt tttctctgct tccactaacc ctgttggtaa ataacgttcg
     8821 agctgttcat agtattctga ataagcttcg aattctccat tcaaatacat caatcgatct
     8881 gctgccataa aaaatttgat ttgttctgtt ccaggagctg gataagtgac cacaaaatcg
     8941 catagctgag acaacttact gttcgcttta tcgataaatc caatcagtgt cgctcctact
     9001 ttcttgattt gttctactgc tttcactact tcttgagttg taccggtaac agaggacaaa
     9061 ataacgatag aatcttttgt taatcttttg tttccagtag tgtaatattc tgcagcatgc
     9121 tgtacaaaga caggcaagtt gcttttccca ttcatataag tgacagcttg catcgaggaa
     9181 gcatacgttc caccgattcc tagataatag acagcgtcaa atttttccgc ataaagttta
     9241 tcgatgattt cttctacttg cggacgtaaa gctagtgcgc cttttattgc tttgatttgt
     9301 tcttcttcat tgaatttcag catgatttcc acctcttata atttactttt caagactgta
     9361 tcaaagtctt caaaaatctt tttgttcaag tcaatacctt tagctactgc ggttttataa
     9421 gcgaatagtt gaaacggaac gacaagcgct aatacagaca gatattcatc acattctatt
     9481 gctaatccaa gtgttttctc gtttcttgct ttttttgtgg taatggtgag agtctctcca
     9541 acgtaccgac tcatatatct ttgcaacttt tgcgaacgtt ccttatttac actttcccct
     9601 tcaataaaga atagcaaatg cgaagcatct gcctccaggt atgggccgtg catataagct
     9661 tctaactcaa atccttgtga cggaacgcgg attgtttcag tcaatttcgt ctctgcttct
     9721 ttagctgttc cccagtttgg accatatcca atggtgacga aacgctgtgc taaacgaaat
     9781 aaactttgat atccatcaaa aaattcttcc gttttttgaa taatcgctgg taaatggttg
     9841 attattttgc gcaactgttg catgtagtct tgttctattt ttttgctgat tttattttta
     9901 cttattccaa ttcctatccc taagagtagt aactgtaaaa cagtcgcaga atagcctttt
     9961 gtaacgaagc ctactgattc taccccggca cctaaatcaa taatttgtgc agcttctaaa
    10021 gcaagtggac tttgcacgtc atttgtgata gcaacaacag gtaacccttg tttttgtatc
    10081 atttttactg cttcaacagt agaagcactt ttcccgcttt gtgacacagc aatcacagta
    10141 tcgattgaag gagaaagttt tccataattg aaaaaataaa aaggttcttg aatatcgaca
    10201 gtaagatcac cataagattc caatgctggc ttcgctgcta aacaagcgtt ataagatgaa
    10261 cccgttgcta agatcagtaa attcactgtt tttttcatat gttctcttgt cgaaaaatca
    10321 ttctttttca agatcgtact tagtacttcc ttttcttcat agatataatc ttgcatcgta
    10381 aacattttct ctgctccttt tttaaaaaat ccctatccac gaaccaaaaa ttccaaagaa
    10441 agctagtccg atcaagatcg ttaatggttt cacttctttc ttcaatagat aaaacactat
    10501 gccaaatgct ccaagacata agatatttgg aacgatatca tcaaaaatac tttgaacagt
    10561 cacagcattt tctcctgaac cgatttttaa aggaatattg atggtgatca tcgtggcagt
    10621 cattgctcca acgaccatca gtccaataat agacgcgcct aatgtcaaac tttccatcat
    10681 accgtttgcc tggatctttt tcaaaaaacc cgttcctaag cgatatcccc aacctgttgc
    10741 tagatagcga aacagaatgt gcggaatatt gaaaatcaaa atgaacaaga tagggcctaa
    10801 aatatttcct tgcatggcta aagaggtacc cacacctgtg gcaatcaatc gcaaagttcc
    10861 ccaaaagaaa gaatctccta accctgcaag aggtcccatc aaagatgttt tgatactatc
    10921 gatcgcagtc acatcaaatt caggatcatc cttattttct tcctccattg cagccgtgat
    10981 tcctaaaatc agtgtaacga tatgtggggt cgtgttaaaa aactctagat gccgtttcaa
    11041 agctgctgcc atttcttctt tcgactgata taactttttc aaaatcggaa tcattgcata
    11101 aacataagcc atattcatct gacgttcata attccaagaa aactccattt gaaaagaacg
    11161 ccaaaatacg tgatttagct cttttttcgt tattttgctg tttttgatct cagaattctt
    11221 catcttcttc tacctcccct gcagttgttt gaagtggtag ttgacggaca ttcataatat
    11281 tgactaccac aactgctaaa atcgcaccaa aaatagctac tccggtcaca ggaatctcta
    11341 agtaagaagc tatagcaaaa cctaagaaaa aatatggtgc aacttgtttg ttgatcagca
    11401 aacgagcaag catcgcaaaa ccaagagctg gaatcaaccc tgtagctact gacaacccct
    11461 tttgaacgaa gtcaggaatc atatttaata gatttccgat cgtattgctt cccaccatat
    11521 aagaaaccat taccacaaca ccaagcatca aggaaagacc gataccggca agcaagtgca
    11581 tatgctcgac tcctttataa tttccttctt ctgcataatt gtctgcttta tggttcataa
    11641 ttggaatcaa aagccctaag taaatatttt tcaatatcaa tgtcaacgta gcaatcggca
    11701 aacctagtaa aagcgcggtt tctgtaccgg ctccagctgt aatagcaaaa gccgtcccta
    11761 aaatcccacc ggtcacaaca tcaggtggaa tcgaagcacc tactgagaac gatccgataa
    11821 atgctaactc taaagttgcg cccataatga tcccagtttt tacatcacct aacacgattc
    11881 ctgtaaacag ccccgtcaca atcggacgag aaagcaacga tgtccctagt gcatattctg
    11941 attgtgcgac aaatgcaaca attcctaata agactgcttg tacaatcatt gaggttcttc
    12001 ctttcttaca aaacttctct tacatccact tttttatctg ctggtacttg acggatttct
    12061 acttctattt gtttgtcaat taatcgtttc aagcgttcct cctcttctgg taaaatattt
    12121 accgcttttc cgatgctgcg agtaccaggt tttgccttga tccctcctaa gttgatggtt
    12181 ttgatttctg gatacgcttc tgccagctta tatgcatcct cgatcgattc cactacgatg
    12241 aataacttat atttatctgt caccccgctt ttcaacgcgg caatcgagtc atcaattgat
    12301 ttgatcacta gtttgactcc ttgtggcttg gctaatttga tcgttgtctt tcgtatctca
    12361 ttcgtaggta catcatcatt agcaatcaaa atacagtctg cgcctattgt ttgtgtccat
    12421 gaaaaagcta cttgtccgtg taataaccga tggtcgactc ttgtcaatac aatcattttt
    12481 cttcctccta aaattcgtct tcttctattt tctgattgag ccgctcgtta caaaactgga
    12541 tcattttttt tgaatcagtt agcacctgct ggatcaaaac agttgtctct acttcagcgt
    12601 ccaaccgaga tactagctca atcaatagtg gcaaattcaa tccggcaacg agatagacat
    12661 gatcccgatt gatatattgt aagaattcgt tgttgacact tccgccaaaa agatccgtca
    12721 gaacaatgat ttctttatct ttgtacctca taaaaagctg ccttactgtt tccgctaaat
    12781 caaaattctc atcagtatag caatcgaata cagtaataga atgatttttc ccatagatca
    12841 gctctaatga atctaatatc cctgaagcaa attttccatg ggaagctaag ataatttctc
    12901 tatccacttt ttcatctcct cttttcactt acacatacta aaaaagcaag ttgcatgcca
    12961 aaat
//
LOCUS       DAIGUC010000071        12801 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.072, whole genome shotgun sequence.
ACCESSION   DAIGUC010000071 DAIGUC010000000
VERSION     DAIGUC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.072"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="NOB46_002414"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="NOB46_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI1059319.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="NOB46_002415"
     CDS             complement(322..891)
                     /locus_tag="NOB46_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCI1059320.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="NOB46_002416"
     CDS             1077..1979
                     /locus_tag="NOB46_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI1059321.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="NOB46_002417"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="NOB46_002417"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCI1059322.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="NOB46_002418"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="NOB46_002418"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCI1059323.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="NOB46_002419"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="NOB46_002419"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCI1059324.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="NOB46_002420"
     CDS             8547..8732
                     /locus_tag="NOB46_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HCI1059325.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="NOB46_002421"
     CDS             complement(8794..9990)
                     /locus_tag="NOB46_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI1059326.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="NOB46_002422"
     CDS             complement(10160..11596)
                     /locus_tag="NOB46_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI1059327.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="NOB46_002423"
     CDS             11889..12698
                     /locus_tag="NOB46_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI1059328.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3820 a         2686 c         2263 g         4032 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc
    12781 agtttctcgg tatgaagtca a
//
LOCUS       DAIGUC010000072        12771 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.073, whole genome shotgun sequence.
ACCESSION   DAIGUC010000072 DAIGUC010000000
VERSION     DAIGUC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.073"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOB46_002424"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOB46_002424"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCI1059329.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="NOB46_002425"
     CDS             complement(2261..2512)
                     /locus_tag="NOB46_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HCI1059330.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="NOB46_002426"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="NOB46_002426"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCI1059331.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="NOB46_002427"
     CDS             3462..3680
                     /locus_tag="NOB46_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059332.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="NOB46_002428"
     CDS             complement(3969..4481)
                     /locus_tag="NOB46_002428"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCI1059333.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOB46_002429"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOB46_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCI1059334.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="NOB46_002430"
     CDS             complement(6934..7377)
                     /locus_tag="NOB46_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HCI1059335.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="NOB46_002431"
     CDS             complement(7378..8166)
                     /locus_tag="NOB46_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1059336.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="NOB46_002432"
     CDS             complement(8163..9104)
                     /locus_tag="NOB46_002432"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCI1059337.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="NOB46_002433"
     CDS             complement(9281..9868)
                     /locus_tag="NOB46_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HCI1059338.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="NOB46_002434"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="NOB46_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCI1059339.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11699..12709
                     /gene="gap"
                     /locus_tag="NOB46_002435"
     CDS             11699..12709
                     /gene="gap"
                     /locus_tag="NOB46_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI1059340.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3530 a         2858 c         2270 g         4113 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgtaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgtattaa ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat
    11701 gacagtaaaa gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat
    11761 caaagaagtc tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat
    11821 gttagcacaa ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc
    11881 aacagaagac tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc
    11941 aagcaaaatc ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt
    12001 ttatacatct gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat
    12061 ttctgcccca gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga
    12121 tgaaaacgac aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc
    12181 ttatttctta aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta
    12241 cacttccaca caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg
    12301 ttcagctgct gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt
    12361 tatccctgag ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg
    12421 ttcattaact gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga
    12481 agcaatcaaa aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt
    12541 ttctagcgat gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt
    12601 aacaactgct ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg
    12661 atttacttgc caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc
    12721 aatcgataaa agaagccttt gactggatcc agtcaaaggc ttctttcttt t
//
LOCUS       DAIGUC010000073        12638 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.074, whole genome shotgun sequence.
ACCESSION   DAIGUC010000073 DAIGUC010000000
VERSION     DAIGUC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.074"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            22..591
                     /locus_tag="NOB46_002436"
     CDS             22..591
                     /locus_tag="NOB46_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCI1059341.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            578..1438
                     /locus_tag="NOB46_002437"
     CDS             578..1438
                     /locus_tag="NOB46_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI1059342.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            1628..2332
                     /locus_tag="NOB46_002438"
     CDS             1628..2332
                     /locus_tag="NOB46_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1059343.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2337..4172
                     /gene="walK"
                     /locus_tag="NOB46_002439"
     CDS             2337..4172
                     /gene="walK"
                     /locus_tag="NOB46_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HCI1059344.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4169..5485
                     /locus_tag="NOB46_002440"
     CDS             4169..5485
                     /locus_tag="NOB46_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059345.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5486..6355
                     /locus_tag="NOB46_002441"
     CDS             5486..6355
                     /locus_tag="NOB46_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HCI1059346.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6410..7219
                     /locus_tag="NOB46_002442"
     CDS             6410..7219
                     /locus_tag="NOB46_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI1059347.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7322..7951)
                     /locus_tag="NOB46_002443"
     CDS             complement(7322..7951)
                     /locus_tag="NOB46_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCI1059348.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8121..9413
                     /locus_tag="NOB46_002444"
     CDS             8121..9413
                     /locus_tag="NOB46_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059349.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9489..10151)
                     /locus_tag="NOB46_002445"
     CDS             complement(9489..10151)
                     /locus_tag="NOB46_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI1059350.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10376..10660
                     /gene="groES"
                     /locus_tag="NOB46_002446"
     CDS             10376..10660
                     /gene="groES"
                     /locus_tag="NOB46_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCI1059351.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            10711..12336
                     /gene="groL"
                     /locus_tag="NOB46_002447"
     CDS             10711..12336
                     /gene="groL"
                     /locus_tag="NOB46_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCI1059352.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4207 a         2153 c         2750 g         3528 t
ORIGIN      
        1 atgaaaaaag gagcggttat gatggaaaaa atgcgtcagc aattaatgga gtgggggaag
       61 gaactagaaa cattccgtct gcctcactgg gaagaactcc ctgacttaga actttatatg
      121 gaccaagtca gaacgttagt tgatcgttat ctttcacctg tgatacaagg agaaaagcat
      181 ccattgctta cctcttctat ggtaaacaat tacgttaaac taggtttgat accagcacca
      241 gttaaaaaaa gatataacaa agaacacgta gcatttttac ttgcaatcac tacgttgaaa
      301 caagtattga ctattcctga aatcaaagaa gggatattgt tccaaggaaa aacagtagga
      361 attcgtgaag cctataatct attttgcgat gaacaagaag cagctgtgtg gatggtcagc
      421 caattagcac aaggtaaatc tcatccgcaa aaattcgacc aggcaacccc tgtagaatat
      481 attgctgtaa gagcggcaac tttatcgttt gcaatgaaac ttcttgcgga aaaaacgatt
      541 gttctagaaa ccgaatattt aaaagaggag aaaacaaatg aaaaacaata aaatcgcaat
      601 tttagtagat tcaggtacgg atgtgccaga agaattgata aaaaaatacg agatgtatat
      661 gatcccattg aaaattattt ataaagatca ggtatataca gataaaattg acattacctc
      721 tgaagagatc tatcaacgtt tgccagagga aatccctggt acatctttgc cggatggtga
      781 gtcgatcaca gaaatctttg agcaaatcaa aaaagacggt tatgaaaagg tacttgcggt
      841 aacaatttcc agtggattga gcgggacata taatgtggtt cgtttaattg cacaacagca
      901 agaagaattg gaagcatatg tactagatac gaaaaatatt ggtattggtg caggtttttc
      961 tgcgatccaa gcagcaaaat ggctggaaga aggagtagaa tgggatcaac tgatcagtaa
     1021 tctgaatgag ttagtcgaaa gaacaaaagt tttctttaat gttgcgacat tggaatatct
     1081 tcaaaaaggt ggacggatcg gtttagttgc ttctattgta ggaaccgctt taaagcttaa
     1141 cccaatcatc tcatgtaatg aagaagggat ttattacaca gtaggaaaag ctaggggacg
     1201 taaaaaaagt ttggataaaa cggttgctta cgtcaaagaa aaaatcggta atgcaaaggt
     1261 cttcaactta gctgttgccc atggggatgc gaaagaagaa gcaattgaaa tggaagcgag
     1321 acttaaaaga gagttcccac aagcaaacca aatctacttt ggccagattt ctccggcatt
     1381 agtagtccac actggtccgg gattattggg tgtcggtgta caagttttag aaggataaat
     1441 caaaaaaagg aaacactgag gtgaaaatca gtgttttcct tttttattga agttagaaca
     1501 aaaaataata aagtattttg cactttcatt ttaattttct cttttgtttt ataggcaaag
     1561 atgaaacaaa agcagaaata cggtataatg agaaggtatg acaataatat ataagaggtg
     1621 gctctttatg aaaaaagttt tagttgtcga tgatgagaag ccgatttcgg atatcgtcaa
     1681 attcaattta gccaaagaag gctatgatgt ttatactgca tatgatgggg aagaagcctt
     1741 ggaaaaagtt gctgaggtag aacctgattt gattttactt gatttgatgc tacctaaaat
     1801 ggacggctta gaagttgctc gtgaggtacg caaaacttat gatatgccga tcattatggt
     1861 aacagccaaa gattctgaaa ttgataaagt cctaggctta gagttaggcg ccgatgatta
     1921 cgtgaccaag ccattttcca accgagaatt agttgcacgt gtcaaagcaa atcttcgtcg
     1981 cggtgccacg gctgcgaagg aaccagaaga ggcagcacct gcggaattga cgattggtga
     2041 tttgacgatc catccagaag cttacatggt gacgaaacga ggagaaacaa tcgagttaac
     2101 acatcgtgaa ttcgaactac tcttttactt ggcgaagcac cttggacaag tgatgacaag
     2161 agaacattta ttacaaacgg tttggggtta tgattatttt ggagatgtac gaacagtgga
     2221 tgtaactgta cgtcgtttgc gtgaaaagat cgaagataat ccaagccatc caaattattt
     2281 agtgacacgt cgtggtgtcg gttactattt gcgtaaccca gaacaggagt aattggatga
     2341 aaagaaaagt ccgctttttt cgatcagtca attttaagat cgctattacc tttattctga
     2401 ttttattgat ctcgatcgaa attattggtg cctactttat acgtggttta gaacgttcca
     2461 cgatcaatac atttattaaa gatatgaatc aaacggtgga atcattagca acaacaatca
     2521 gcccggaatt gaatcgaaaa gataatgcag atgatgaaga ggtaaatgcg aatatcaaaa
     2581 gatttattga aaacagtgcg actagcgata tcatcgaaat acgggtcgtt gacgaaaaag
     2641 ggatcatccg aggaacaacc gatgtcaatg aacaaagcgc tgtgggaaag aaaaatgatt
     2701 atgttgatat caatgatttc acgactaaac gttatgttgc tttagataac gacgataaac
     2761 gggtgaatat caatgttcaa ccgatcctgt ccccgaccgg cgatgccgtt atcggggctc
     2821 tttacgtcaa aagtaatatc gaacaaaaat attcggaaat caataacaca gcagtcattt
     2881 tctttactgc ctcactaatt gcggcattta tttcaatgat cgtatctgtt ttagttgctc
     2941 gttcgattac acagccgatc ggtgaaatga gagaacaagc cattcgaatc gctagaggag
     3001 actacagtcg gaaagtcaaa gtgcatggac aagatgaact tggacagctg gctgatacct
     3061 tcaatcagtt agctgaacgt attgaagaag ctcaagatac aatggaagct gaacgcaatc
     3121 gtttggatag cgtgctatcc catatgacag acggcgtcat tgcgacagat cgcaggggta
     3181 aagtcattac gatcaatgat atggctgttt ccttgctaga tatcaaaaac gaggaagcaa
     3241 tcggacaatc gattttgaca cttttagata tcgaagaaga atatacgttg cggaaattat
     3301 tagaagatcc aaacgaaatg gtacttgacc gttcaaccag tacattggaa agtgatcaga
     3361 tgatcttgcg agtagacttt tctatgatcc gtcgcgaatc aggttttatc agcggattag
     3421 tagctgtctt gcatgatgtg acagaacaag aaaaaacaga acgggaacgt cgtgaattcg
     3481 tctctaatgt ttcccatgaa cttcgtacac cgttgacaag tatgcgtagt tatatcgaag
     3541 cattgagcga aggtgcgtgg aaagacgagg aagtagcacc aaattttttg aaggtaacgc
     3601 tagatgaaac agaccgaatg attcgaatga tcaatgacct cttaaatcta tctcgcatgg
     3661 atacaggtaa tacccagctt caattagaat atgtcaattt caacgagtta gtgaattttg
     3721 ttcttgaccg gtttgatatg atggtgggaa atcaggaaaa aaattataag atccgtcgtg
     3781 aatttacgca aagagatctt tgggtcgaag tagatacaga taaaatcatc caagtagtcg
     3841 ataatatcat gaataacgcg atcaagtatt caccagatgg gggaacgatt acttgtcgct
     3901 tattagaaac gcataataac gtggttttaa gtatcaccga tcaaggattg gggattccta
     3961 aaaaagatct gaaccgagtg ttcgagcggt tctatcgagt agataaagca cgtgcaagag
     4021 cacaaggtgg gacaggactt ggattagcta tttctagaga agtgattaag gcgcatcgag
     4081 gcgctatttg ggcagagagc aaggaaggaa aagggtcgac tttttatatc tcgctgccat
     4141 atgaacctta tgaggaggaa tggtgggaat gagaatctct gaaaaagtcg ttcgtatagg
     4201 actcattttg atggttgcgt taagcatata cttctcttat gcaatctggc tgagcccagc
     4261 aggaaaaagt tcaatcaacg tagatgagac aaacactcaa atgatcgagt ctcaaagcaa
     4321 tcgaaaaact tccgaagtct ttcttccgct tcatgttaca tggcaccatt cgggaatgat
     4381 ccaagaaacc aacagtgaaa atctcgtgta ccgattgcaa ttgatcatcg ataaagcaag
     4441 atttggaaag ctttctgaag tagtttcagg agacaaatca cagtttgaac aggtgaaaaa
     4501 tctgaactct ggttttgagt tggcctataa tgcgcctttt ttgctaagag aatacaagga
     4561 agcatttgat ttagatttag atgtgtcgaa cttggcaaaa gaaagcgaaa atatgtattt
     4621 tactagaata caattcgatc aaggaaataa aaaaatccga tttttgaatt attcgaacca
     4681 tctcgtatat gaagcaaata tttcgttgaa ttggacagat atcaataaag aattaacagc
     4741 aaaagacaca aaatggacag aaatgacaac agaaccatcg acgatcgaca cgcaatatgc
     4801 tacgaaacat tcgatcaaac tgaaaaagta tagttatatc ctgtcacagc aaccctatac
     4861 actttttaga aatgcttttt tccagaaacc agatagcgtg aaaaataatg atgaaagcaa
     4921 tgaattgatt ttttacggtg ggaatgaaac aatgtctatc cattcggaaa cgcaagtagt
     4981 tgattttcgt ggagagctgc cagagaaaaa agaaaatgct agtgtatttt ctgaaagttt
     5041 cccctatatt agcaaattag gcagttcttt agggaacctc agatattttg accgcagtga
     5101 caatacgatc gattatcgga tattcgtgga aggcttcccg gtttttggga cagacagcag
     5161 aggacagatt ggtgtggaag ttggcggtga aacgaatggt tctgtgcaag tgaatatcca
     5221 aaccagtttg aatacgattc aagtgccgat accttcagac gaagaagtag aacttgcaag
     5281 tacgaatgaa atcatccagc agttaaaagc taagggagca gatagcaaca agattggttc
     5341 agtgatcgtt ggctatacat ggcaaaatgt caaagaaacg aatcgtgtcg ttgatctctt
     5401 acctgaatgg tatgtgaaat ataaagataa ctggtattca gctaacgacc ttctggaaaa
     5461 attacctgga ttggaggcga attaattgga tttcaaaaaa atcgaatgga tatttttcgt
     5521 cgctttttta gggttgaatg tgtttttatt cagcagttat catgacgcgg tataccaaga
     5581 aaacaatgtc attcgctcta atcagactga atcaatccaa caacgtctgg ctagcgacga
     5641 tatcacttac acggggaaga tttcgtctga gaacaagcaa ggctattatc ttagcgcgga
     5701 gcagaccaat cttagcactt cattagcgaa ttatcgcaag gctggtaaaa gcggcttgct
     5761 ggcaagtggt gtgtttttag acggtgatgt tttgacgaaa tctttatcca gttcagatgc
     5821 tgaaaagaac gtgatcgatc cagataaaat tagtagttcc ttggaagatt ttttatctaa
     5881 caaagacaat attttattcg gtaatgatta tgtgtacacg aaaaactttt ctcatttaga
     5941 agaagaacca ctagaaatcc aagcaagcca agagtatgaa ggcatcccat tcaatgatga
     6001 tacagcaaaa atcgttcttt ctttagaaaa aaacgataat gattatagca tcacgaaata
     6061 catgcagacg catttatctg atatcgagca gctgcgcgaa aagacggaac tgtatacgga
     6121 agaggaagca atcaatacat tgtacatcaa taacaaaata ccaagaggat caaaaatttt
     6181 atggcgtcag ctagcttatt cctgtattct gaaagtccgg gaaaaaaatg tgtatgttcc
     6241 tgtttggcat gtagcgatcg aaacaagcga taaagtggtc caaattgaga gtgtcaacgc
     6301 tttcagcaat acgatcgtga caaacaatac tgtaccaaaa gtggaagatc aataaaaaag
     6361 cgagtataat gaaaaaagtt tacaaagtaa gaagggaagt aggagtcaaa tggctgaaga
     6421 aaaaccagct tttaaaatca gtatcctagc aagtggaagt tcgggtaatt cactttatat
     6481 cgaaagtgaa aaaaaacggc ttttggtcga tgcaggactt agcggtaaaa aaatcacttc
     6541 cttgatggct caaattgatc ggacaccgga ccaattagat ggaatacttg tgacgcatga
     6601 acatcgagat catatacatg gcgtgggtgt cttggctcgt aagtatcatt tggatgtttt
     6661 tgccaatcag cagacttggg aagcgatgga accactgatt ggaaatgtac cagtggaaca
     6721 aaaacatcta tttgagatgg ggaaagtcag aacattcggc gatatcgata ttgagagttt
     6781 cggcgtctcc catgacgcag cggctccgca attttatcgt ttccataaag aaaatcggtc
     6841 attcgtcatg ttgacggaca ccggatattg cagtgattat atgcgaggtg tcattgaaaa
     6901 tgccgatggt tatttgatgg aaagtaatca tgatcttgag atgttacgca tgggacctta
     6961 tccgtggaat ttaaaacagc gtattttagg agatagagga catctttcca acgaagacgg
     7021 tgcacttgtc atgactgatg tgatcggtaa tcggaccaaa cgaatctatc ttggccatct
     7081 tagcaaggaa aacaatatga aagaacttgc tcatttaaca atggaaaatg ttttgaaaga
     7141 aaaagatttt ggcgttggac atgattttga aatctatgat acagatccag atgaagcaac
     7201 tgagctattt tcgatttaaa cagttcaatc aataaaaata taaaaagcag aagataaaat
     7261 caatcagggt tggttttatc ttctattttt atttttttag catattaaaa aaataaccgt
     7321 attatcgact gactacactg atgtgctgct tttcatgttt ctcatccagt atctcatcta
     7381 ctaatgcaat cgcgtaatct gccatgctga tcgtactgtc gccagcagcg tttctttgta
     7441 aataatcatc acttaacaaa taagtacctg tacgtttgcc atgtggatca aataaagaag
     7501 ctggactgat ataagtccaa tgtagatttt tagattgttt caattttaac aatccttcgt
     7561 acatattgaa agctgttgga tagaagggtg catttttagg tacttggtca atcatacgag
     7621 tcgtcttttc tgtatctaag aataacgaag aggcaccccc aacgacaatt aagcgtgtat
     7681 cggttccttc aagcatctca atcaaatggg acaaagaagt ttgatgcatt tcttcttttc
     7741 ctttgggagc gttgaaagca tcaacgacaa catcaaaaga tgcaagatca gtagttgtca
     7801 actcaaataa atccttttgt ataaacggaa catctgatgg caatttttct ggatgacgca
     7861 cgattgccgt cacgtctaaa tctctggaca atgcttcgtc taaaataaat gaacctgcat
     7921 ggccagtagc tccaatgagt gcaattttca taaaaaacct ccttttttat tcctgtccat
     7981 tgtaagcagt tgctgaatat tcgtcaaaga atccgatttt tgaaaagctc agtgcgcatt
     8041 cctttcatgg ttcgtgatca ttgggtatag ttaaattaag aaaactgatt gataaaaata
     8101 gaagttgaag gagataagaa atgaaagagt ggttagatcg tgccttttta ccaatgataa
     8161 catctgttgt gaatcttaga cccttaactg ctttgcgtaa tggaatgact tacacgatcc
     8221 caataattat tgttggctcg ctgtttttct tatttgctca ttttcctgtg gattacatcg
     8281 ctcagtggat agacaaaaca ggattttcta tgtattttac acaagtatac caggctacat
     8341 ttgatgtgat agccttttgg atcgtttttg ccattgcata cgcttatgca aaagaagaag
     8401 acatcgatcg cttaccagtc ggcataacag ccttgtctgc ttatctactg cttattcagc
     8461 cactaaatac tcagatagat actgtctgga caggtgctga agggatacta ggagcagtta
     8521 caactgggct catcatcgga tggggctatg cacgtttagt aagacttgcg aaagggtgga
     8581 agcaaagaga gaagatacct gaaaatgttt ggcagtcttt tacttcattg attccaatca
     8641 ttgttatagt cacttttacg cttatcggtt cagcggtttt tcaacagttg ttcagaatga
     8701 ctgttgttca aggagtatgg acatatgtcc agcttcccat tcaatcgttc atagacacgt
     8761 tgtttggtgt gcttttatta ggtttttttg ttccgttttt atggttattt ggtcttcatg
     8821 gatctgcgat ggtcaatggg ttggttagtc ccgtcttgca agcgaattca ttagcgaatg
     8881 cagaaatctt agcctcagga caagagttga cggtggcaaa tggcggacat atcgttactc
     8941 agcaatttct cgatcagttc atgacggtta cgggtgctgg attgacgtta ggggctgtat
     9001 tttttatgac ggtttttgcg aaatcgaaga aatacagaga attaggaaat cttgctcttt
     9061 taccagcctt tttcaacatc aatgaatcaa ttattttttc cacaccgatc gtgatgaacc
     9121 cgatgatggc tgttcctttt attttcgcac cggtcgtttc aggattgatt acctattccg
     9181 ctttatattt tggattcgtt cctttattta cagcagtcca agtcccttgg acaacaccgc
     9241 cgatcctctc gggtttctta gtaggcggag tgcctgcagc gattttacaa ggtatcgtgt
     9301 tgtcaattag ttttttcatt tatttcccat ttttgaaaaa aatagattct gcaaactgca
     9361 aaaaggaaag acagacaaaa aatgatggag cagcagaaaa gatgaacgac taaaaaacaa
     9421 aaatactcct gtcgctttag attgggaaaa tcaccaatct aggatgacag gagtatttat
     9481 agtcatgttt atactagccc tttttggaca gctaattgaa caagaacaac taatgtgttc
     9541 attcctacgt gtgtgatcat cgatgtccag atccgaccag ttgctttgta ctctaggctg
     9601 aagaagaaac ctaggaaaaa gtagattagc agatgaccat cattatgagc aaacgcaaac
     9661 agcaaagagc tgatcactgc tccgacccaa aaatttgaat atcgactgat gatccccagt
     9721 atactgcggc ggaatacgaa ctcttccatg atgggtccag caacagttgt cgccaaaata
     9781 aaagcgggtg cttccatgat catctggatg atattttgtg tattctcgga aggggttgct
     9841 ttgccaaaca atacagattc taacatgaca gcgatgcttt gcagaatcaa tgcgacaaag
     9901 attccaacca atccataaat aacaatcttt ggagcagaag ctttttttac cgctgattcg
     9961 atcgctaagg gttcacgttg cttaaaataa aaaatagcta ggacaacggc gcctagtata
    10021 tacatgactg cagttgctgt gatcaattca gacgtagatt ttacaagtcc tatcgaagct
    10081 aggatcaagg gtgagataaa aattagacca tagcaaaaaa tgctgaggaa gctatatttt
    10141 tttaaagaca tgtaattcct ccttttaagg gataacaagc atgcaaggca agcttatatc
    10201 gattgatttc aattatatca taatttcaat aagcagctgt cagaataaaa tttcttttct
    10261 ttgatttaaa agcttgcaaa aaagagggag aatgagtatt attaaaaatg taggttagca
    10321 ctcgaaggtt aagagtgcta acagattaaa aaaagagtta tcggagggat ttatcgtgtt
    10381 aaaaccatta ggtgatcgcg tcattatcga agtcgcaaaa gaagaagaaa aaactgtcgg
    10441 aggaatcgtt ttagcttctg ctgctaaaga gaaaccccaa actgggacag ttgttgcagt
    10501 cggtgaaggc cgtttgttag aaaacggtga aaaagttcct gccgctgtaa aagcaggcga
    10561 ccaagttatg ttcgaaaaat acgccggtac agaagtaaaa tacgaaggaa aagaatatct
    10621 gatcgtcgca ggaaaagata tcatggcgat tgttgagtaa atttggaaga taaaaaaata
    10681 atcaaaaata atcaatgagg tgaatcaatc atggcaaaag aattgaaatt tgcagaagac
    10741 gcacgcgcag ctatgttacg cggggtagat aaattagcag atacagtgaa agtaacatta
    10801 ggacctaaag gccgaaatgt cgtactagaa aaatcttacg gctctccatt gatcacaaat
    10861 gatggtgtga cgatcgcaaa agaaatcgaa ttagaagatc attttgaaaa catgggtgca
    10921 aaacttgtat cagaagtagc atcaaaaaca aatgatattg caggagacgg tacaacgaca
    10981 gcaactgttc tgacacaagc aatcgttcgc gaaggtttaa aaaacgtaac tgcaggtgct
    11041 aatcctctag gcattcgtcg cgggatcgaa ttggcaacaa aagcagcagt cgaagaattg
    11101 cataatatct caactgttgt tgattcaaaa gaagccattg cacaagtagc agctgtttct
    11161 tcgggttctg ataaagttgg acatttgatt gctgatgcaa tggaaaaagt tggaaacgac
    11221 ggtgtcatca caatcgaaga atcaaaaggg atcgaaacag aactagatgt tgtagaaggt
    11281 atgcagtttg atcgtggtta cttatcacaa tatatggtaa cagataacga caaaatggaa
    11341 gctgttctag aaaacccata tatcttgatc acagacaaaa aaatctctaa catccaagat
    11401 attctgccat tgttagaaca aatcttgcaa caatcacgtc cattgttgat tattgctgac
    11461 gatgtagatg gtgaagcatt gccaactctt gtattgaaca aaatccgtgg aacattcaac
    11521 gtagtagctg taaaagctcc tggtttcggc gatcgtcgta aagcaatgct tgaagatatc
    11581 gctattttga caggtggtac agtaattact gacgatctag gtttagaatt gaaagatgta
    11641 acaatcgaaa acttaggaaa tgcttctaaa gttgttgtag ataaagacaa tacaacgatc
    11701 gtagaaggtt ctggagaaaa agaagcaatc gaagctcgtg tgcaattgat caaaaaccaa
    11761 attgctgaaa caacttctga ttttgaccgc gaaaaattac aagaacgctt agctaaatta
    11821 gcaggtggtg tagctgttgt taaagttggt gcagctactg aaacagaatt gaaagaatta
    11881 aaattacgca ttgaagatgc attgaatgct acacgtgccg cagtagaaga aggaatggtc
    11941 tcaggtggtg gtacagctct agtgaacgtt atcagcaaag tttctgctgt agaagcagaa
    12001 ggagacgtgg caacaggtat caagatcgtt gttcgtgctt tagaagaacc aattcgtcaa
    12061 atcgctgaaa acgctggtta tgaaggatca gtgattgttg ataaattgaa gaacgtggaa
    12121 ctaggcactg gtttcaatgc tgctactgga gaatgggtaa acatggttga agcaggtatc
    12181 gtagacccaa ctaaagtaac acgttctgcc ttgcaaaatg ccgcttccgt ttctgccttg
    12241 ttattaacga cagaagcagt cgttgcagat aaaccagaac cagcagcgcc agcagctcct
    12301 gcaatggatc catcaatgat gggcggtatg atgtaagaaa aagcaacttg cttatctaca
    12361 actgatcatt agtgaaagac agataaaaag aggctggaac agaagcgttt aactccaaga
    12421 aataagaaga aattcacgga aattgctttt caaatttttg tgaatttcag cttatttccg
    12481 aaggagttgc ttctgcttcc gctgtttata cgtgtttaga gcgtgagaca aaagtgttct
    12541 ttacttttgt cccacgctct tttttgtgtg taattataat gaaaatagtt atttttaata
    12601 gttataatat tttatctatt aaaagtaaat atccattc
//
LOCUS       DAIGUC010000074        11930 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.075, whole genome shotgun sequence.
ACCESSION   DAIGUC010000074 DAIGUC010000000
VERSION     DAIGUC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.075"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(49..1467)
                     /gene="nhaC"
                     /locus_tag="NOB46_002448"
     CDS             complement(49..1467)
                     /gene="nhaC"
                     /locus_tag="NOB46_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI1059353.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1870..3093)
                     /locus_tag="NOB46_002449"
     CDS             complement(1870..3093)
                     /locus_tag="NOB46_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCI1059354.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3124..3963)
                     /locus_tag="NOB46_002450"
     CDS             complement(3124..3963)
                     /locus_tag="NOB46_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI1059355.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3980..4660)
                     /locus_tag="NOB46_002451"
     CDS             complement(3980..4660)
                     /locus_tag="NOB46_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1059356.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4662..5735)
                     /locus_tag="NOB46_002452"
     CDS             complement(4662..5735)
                     /locus_tag="NOB46_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI1059357.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5791..6029)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6072..6305)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6382..7053)
                     /locus_tag="NOB46_002453"
     CDS             complement(6382..7053)
                     /locus_tag="NOB46_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1059358.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7140..9818)
                     /gene="mgtA"
                     /locus_tag="NOB46_002454"
     CDS             complement(7140..9818)
                     /gene="mgtA"
                     /locus_tag="NOB46_002454"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCI1059359.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10477..10914
                     /gene="ndk"
                     /locus_tag="NOB46_002455"
     CDS             10477..10914
                     /gene="ndk"
                     /locus_tag="NOB46_002455"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCI1059360.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10936..11802)
                     /locus_tag="NOB46_002456"
     CDS             complement(10936..11802)
                     /locus_tag="NOB46_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1059361.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
BASE COUNT         3449 a         2591 c         2015 g         3875 t
ORIGIN      
        1 gtaaaaggga ttgtgacaaa agtcttgtca caatcccttt ttatgttttt attgttctaa
       61 ttgcgctgtc ttgcttactg cttcttgcgg tttcacaaat ttttttgaga ttccccaacc
      121 tgtgaaggca ctgaccatcg aaaacacagg agaaagcaaa ctgaaaaata cgaatggcaa
      181 gtaagtgagt gtaggaatac caaatgtact tgctacgaaa cttccggcaa ttccccaagg
      241 cactaagtag ttgattactg ttccaccatc ttctagcgtt ctacctaata cagttggatc
      301 aaatcctgct ttttcataag tttctttaaa tgcattacca ggcagaataa cagataggaa
      361 ttgttcacca ataaaaatat ttactccgat acttgtcatc aatgttgtaa aaatcaaatt
      421 tggtgtgttc gtcatctttc ttgatactcg ttccatcacg gttgagatca agccaaattc
      481 gatcaacaat ccacctaatg acaaagttag aataatcaat gacacagtag gcatcatact
      541 ttcgattcct ccgcggctaa gcagtgaatc gatttgttgg tttccagtat ttgaaacaaa
      601 ccctgattcg atgaccccag ccaacttcgt taaggaagtt tgtgggtttt gaataaaaat
      661 cattcctact gctacagcga tattcaacaa aatcgttaaa attgccggca cctttttcca
      721 tgcacacagt aacattaaaa ataaaggaat cagtgaccag attgaaatag taaagtttgc
      781 ttctagaaca tcagtcactt cacgaataga tgaaagactt gcggctttac ttgtgtgtcc
      841 taaaatcatg aataaaaaga aagaaacaac aaatgccggg acagttgacc acatcatatg
      901 cttgatgtgt ttgaacaaat cggcatcaac aatagctgct gctagatttg ttgattcgga
      961 taatggagac atcttatctc caaaaacggc acctgaaaca atagctccaa caaccagcgc
     1021 tggatttaag cctagtgttg tcccaatacc gaaaaatgca atcccaatcg ttgacataac
     1081 agtaaaggca ctccctacag cgctacctac gattgcacac acaacaaata cagaagggac
     1141 aaaccactgg acactgatca atttgaaccc aatgaccatt agagttggaa tgatccctgc
     1201 ttgtatccat acagcaatca atgaaccgac taaaataaaa ataaagattg ggatgattcc
     1261 tggtttgatg ccattgatga ttccttcgtg cagccaatct gtcgggtatc tttttatcac
     1321 tgcatacaac atgaccattc cgatcgctgc taagatcgtg atattaggtg agacctttaa
     1381 tccgacaacg ccaatcgcaa tgcctaaaac aataaccatt aatacaagtg ttgcttctaa
     1441 aaaacttggt gttccttttt ttcccatgat aatctctcct tttttagttg ttcttatgtt
     1501 ctaaaaaagt taagatatcg gattactccg ccgcaattca tccgcgattc ctcctttata
     1561 aaaataaaaa gacctgtttt aaactaagga cgaatgactc cgcggtacca ccttaattaa
     1621 aaacagatct gtttttcact ttcaaacttt tattcaaatg tatggacttt ccatgtaatt
     1681 cgtcaattag gcttgatcgg ttcacagcga ccaccgactt tctgaacaaa acacctaacc
     1741 gctactgcgt gaaaagttga cttgtacgaa gtttaccttc cataagatca tttgtcaatg
     1801 aaaaagaaaa tattttttca tttttctgaa aattattttt ataactttca cacacaagtt
     1861 tattttttac tagaaagtag cgccctcttg tttttttctt gctactattt cttgatgttc
     1921 ttgcttgatt ctttctaata gctttggctc tttcaacaga tcaagagctg tattggcgag
     1981 tagttctgct gcaatcgcaa tagaagcaag gcctttgtca cttttagcag cagctttgaa
     2041 ttcttctgtg tgtccggcaa tatatgtctc agagattgct accgtaggct ggattgttgg
     2101 tatgacttgg ctgacatttc ctacatcaga agaaccgaga cttgttcttt gttccgtttc
     2161 tatttcttca tctggaacac ctgcttcttt tgcatgctgg aagaataagt catcaaaaga
     2221 aggagtaacg atgacatcat caactgcatt ttggaacaat ccaaactcaa aagtcgtgcc
     2281 cgtacttatc gcagcacctc gtacgatatt ttccactttt tcatatactt tatctaatgt
     2341 ttgccgattt cctgcacgta aatagaaacg tccagcagcg taatctggaa tgacgttggc
     2401 agctactcct ccgtctgtaa tgatcccatg gatattgaca tcttttggca attgcaagcg
     2461 tagagcgttg attccattaa acacttggat caatgcttcc aaagcattta ctcctttttc
     2521 aggtgctgct gctgcatggg aagcgacacc gtaaaatttg atgtcgactg gatcattcgc
     2581 taaagattct gtcgttttcc cataacgaaa agctggatgg acgcataacg ctacatcgac
     2641 atcctcaaaa aaaccttctc gaacaaagct gcctttagct gatccgttct cgcccccttc
     2701 ttcccctggg gtgccatata cacggatttc tccaccagtt tcatcaatga attgcttcac
     2761 tatgctggcg gctaatacgg agtaagtacc aaacaaatta tgcccgcatg catgaccaat
     2821 acctggtaaa gcatcgaatt ctgccaaaaa ggcaattgtg ggaccgggtt tattggaaat
     2881 ataacgtgca tcaaaggctg ttcggtgtcc agctacttct ttttctaccc aaaacctttc
     2941 tttttctaat tgtttaatca acgctgctga ggaataaaac tcatagttac ttacttcagg
     3001 atgttcgtgg atatctagag caagtgcttg atattctggt aaacgatatt ggattagatc
     3061 cttcaattgg tttgttgaga ttgttgttgt cataaaaaat tcctcctatg ctagtcattt
     3121 ttcttatttt ctcccgaatg tttcccatgc aggcacgctt gatccttttg atgttttctc
     3181 gattactttg actgtgtctt ctgtttgata agcgtctact attttttgat acgttttatt
     3241 gttttcatct tcttttcttg caacgatgat attcacataa ggacgtgcat ggtcatccac
     3301 tggttctaag aagatggcat cagaagcagg attaaatcca gcatctacag ctacaccgct
     3361 attgatcact gaaatgtcta catctgacaa agcacgtgct gtttgggaag catctaattc
     3421 agaaatgtct agattttttc tattctcggt aatatcagaa acagtgggcg cttgtccttt
     3481 tgccttatcc actttgatca atccagcagt ttgcaataac agaagagctc tgccgccatt
     3541 tgtaacatca ttagggattg ctacttttgc tccgtctttg atatcagcta catccttcaa
     3601 agtgttagaa taaattccca gcggtgcatt gacagtattt ccgatcgata ctaaatcagt
     3661 tccgtgttct ttattgtaat tgtctaaaaa gaattgatgt tggaaagaat tcaaatcaat
     3721 cgatccatct gctaaagcca catttggttg attgtaatct gtaaatttca cgtattccaa
     3781 attaatgttc tcctttttca aacggtcttt cacgttgtcc catacatctg tatcttctcc
     3841 aataatccct agttttacga tagtttcttt tttgtcagtt gtatctgctt ttccttggct
     3901 acaccctgcc aaccaaataa ttgctacaaa tgtaatgact acaaaacgaa taattttttt
     3961 cattttttct cctccacttt caatgtgtaa tttttttaat cagttgatta ctgataaatt
     4021 gacttaaaaa aactaagatt agaatcaata atgtagccac aatcgttaca tctgtttgga
     4081 atcgattata ccctctcgat atagcaagat tccctaatcc gcctgcacct actgctccag
     4141 ccatggtagt cagtccgatc acgttgatga tagtcaacgc cgagacccga atgataccag
     4201 gcaaaccttc taacaaatac acacgtaaaa tgataccgat tggactggtt cccatcgctt
     4261 ctgccgcttc gatcacccca ggatcaactt ctagcagtgc gttctcgatt tgacgagcaa
     4321 aaaacggaac aactccaaaa atcaatggca ctaaagctgc tttcgcacca atcgtcgttc
     4381 caactaagaa acgagtagtc aatgctaaaa gagaaagcaa gataatgaaa gggatggaac
     4441 gaatgatatt gatcagctta tcaagtattt caaatagcag acggttagct agtaatccat
     4501 tagggcgtgt cactactaac gtcacaccta agatgattcc aatcatcccg ccaatgaatg
     4561 ctgtccaaaa agacatatat agtgtttgct tcgtcgcttc gacaaattca tccggaatca
     4621 aataaacatt gggcaaatat gttttaaaga aatcagtcat tttatcttcc tccttcgatc
     4681 actttgatac gactatctaa atcgtttttt tgtaaaatat ttatttttac accagatttg
     4741 atcaaataat ccaatgcttt tttccgctgt ttggtttctc cagctaaagt aacgatcaaa
     4801 ctccctaacg gcgtttcttg taataactct acattgccat ataaaatatt cgctgttact
     4861 tgatatttgc tgtacagatg agcgattaga ggttcgttcg tctgatttcc aatataactt
     4921 aattccacca gccatttatt ggcgatctga tcggcaaaag cagaatgggc aatgatcgtt
     4981 tctaatgctt ggtcaagatg agtagctgtt cgaataaaat ctttggtcaa ttcttcttca
     5041 ggattgctga agatctggat gctgctacct ttttcaacga ttcttccatc ttccataacc
     5101 gctaccttgt tgcagatttc tttgacaact tgcatctcat gagtgatcag gacgattgtt
     5161 aaacctaact ggcgattcaa tttttttaac aatgcaagga tctgaagggt cgttttcgga
     5221 tcaagtgcac tggttgcttc atcacataat aataccttag gttcattcgc caaagctcgt
     5281 gcgattgcta ctcgttgttt ttgtcccccc gacagttgtt taggataagc agatgctttt
     5341 tcttccaaac cgacaagttc cagtagttca ttcacttttt gacgacgttc ctgtttcgat
     5401 tttccagaat actttaaaga aaaatcaacg ttgtcaaaaa tagttcggct ttccattaga
     5461 ttgaaatgct gaaagatcat accgatggcc tttctttctt ttcgcaattc tttgggagag
     5521 agctgactca gattcgtctg attgacaatg acttctcctg ctgttggttt ctgcagcaaa
     5581 ttcatcacac gaactaacgt acttttccct gcacctgagt aaccgacgat tccataaaca
     5641 tcgccttttt caatcgttaa atctacagaa tctactgcct gtatctcttt ttctttttgt
     5701 ttgaaacata cagaaacatc tcgcaattca atcattaaaa ttcctcctta tctaaaaaaa
     5761 gcgtcctcaa gaaaatgaaa atgtcatttt cttgaggacg cttttttgcg tgttaccacc
     5821 tcatgttcaa gctgtgttca cacacaactc ctcttcaagt acgatcatac tctagcaaga
     5881 tatcggtcgc agccgtcatc gccttacatc tatgctcggg atgaattgct cgatggccat
     5941 tttccaatag tcgttccttg cttcttctca gctaccgaag ctctctgtca aaggttcttc
     6001 tatcgtactt accatttcaa tgcaaataat attcaaaaaa aaagtccttt tactaacata
     6061 aactatgtca gtaaaaggac gacgtatcgc ggtaccacct tttttcggaa gtttccttcc
     6121 ctcaagccca acatctctaa aagagagatt ggcgttcgtt ttaacggtcg aacagttccg
     6181 aatttgccta cttatcgaca aattattctc caaggccatt ttcagctttt cttacttgac
     6241 tcttctcacc agccagagcc tctctgcaaa gtttccaaac ttactttcct tttcaacgaa
     6301 atcgatattt tgttgttggg attaatctac atgaggaaaa ctgaaaagtc aagtacgaaa
     6361 ttcaaattat tttttctata tttatttttc tgttttttta tttaacattt caataacagt
     6421 tcgaagatct tttccttccg caagaagttt caatttttcc ttttcttcga cggtataatt
     6481 tcggacaaaa ctggaatcag gtatcaaaac aacgcctaat cctgctcgtg aagcagctgt
     6541 tgctcctact aaagaatctt ccactgcaaa ggctgaacta gcttctaatc ctgttcgttc
     6601 caaagctgtc agataaggaa tcggtgaagg cttgttctcc gacacttcgt ctccgaatgt
     6661 aaacgtgtcc aagtaatcag ctaatttaaa gtgatccaag atatctgttg ctcttttcgt
     6721 aacagtggtc gtagcaatgc ctagtttcat atgacgttct tttaagtctg ccaatatttc
     6781 ttttgcatat ggttttaagt ggatggctcc gcttgtcagc tgttgataaa aatattcttc
     6841 acgcttcgct cggacttcct gtactttttc agggctacct gctgctttca ctaaaatatc
     6901 aaaactttgt ttccagtttt ttcctcccca agcgtcaacg atttcttttg ggatatggat
     6961 atcaaattgc tgaaatcccc aaagccagcc atcacgatac gttttttctg tgtcaactaa
     7021 caaaccatct aaatcaaata ttgcaccttt catctataca ttaatccttt ccaaaacaat
     7081 acacatagtt tagcacgact ggtccaaaaa gaacagaagc aaagaaccag ccttctcgtt
     7141 tataagagtt cttggaatcg acggatatag attttcttca cagctgtcac aagcgccaga
     7201 taagcgatga ctgtagcaaa taaccataac cagtaattgc caggaagtgg catcaagcct
     7261 aattcagcac caaaacttgt aaaaggaagg acagaaccga caataattcc taatgtagtg
     7321 ataacaaaca tggcaaatgt tgcgttgctt tggataaatg gtactttcgg tgtacgcagt
     7381 gcatggagca ctaaggtttg tgtccatagt gattcgacaa accatcctgc atggaataat
     7441 gcgatgaaaa tcactcgctg tgaactatcc aatgtatgga aacttccgcc cactacagca
     7501 ggacaaataa caaaatacat caacaagtaa gtagtaatat caaatatcga acttgttgga
     7561 ccaaagtaaa ccatgaattc cccaatacta gatgcattcc atttttttgg ctcgtccaaa
     7621 tattctttat ccatccgatc ccatggcaag gaaatgcagg aaacatcata gatcagattc
     7681 aaaaacaaaa gttgtaaagg cagcattggt aaaaatggca ggaacgtact tgcaatcagc
     7741 acggaaaaca tattgccaaa attagaactt gctgtagcct tgatatattt catgatattc
     7801 ccaaaagttt ctcgtccaga aagaaggcct ctttccaaaa tcgtcaaatc tttttctaaa
     7861 aggatcacgt ctgcagattc tttcgcaata tccacagctg tatctacaga aataccgata
     7921 tcagccactt tcattgcagg agcgtcattg ataccatctc ctaaaaatcc gacagtatga
     7981 ccatttttac gtaaagctgt cgtcaaacgt gctttttgct gaggattcaa ttttacgaat
     8041 acttcatggt cttcagctac ttgtgctaat tcatgatcac tcatttccga gattttctca
     8101 ccggtaacca attcattgat ctctagacct acttgacggc acactgaacg tgtaactaat
     8161 tcgttgtccc cagtcagaac ttttacagct acaccatgtt ctttcagagc tttcaacgct
     8221 tgtttcgttg tttcttttgg tggatcaagg aaagcaagat aaccaatcaa aaccatgtct
     8281 gactcatctt tgactgaaaa ttctccaacg acgcttggat tggtcttttg tgcgacacca
     8341 atcactcgta agccatcttc attaagtgac tgtacttttg caagtacggc ttcttttcgt
     8401 tcttttgtta atggtgtaac agtaccgcca agatcaataa atttagaaat gttcagcatt
     8461 tcttcaatcg cgccttttgt gatcatttgt gttttaccag ctggatcagc aaccacaaca
     8521 ctcatacgac gacgttcaaa atcaaaagga atttcatcca ctttttgata attgatctta
     8581 tctgtatcta aagtttctgt tgcttcatca atgatagcca catctaacaa atttttcagc
     8641 cctgtttgat agtagctatt tagatacgca tggcgcaaaa cacgatcatc ttcatttcct
     8701 tcacaatcca tatgatattc aagaatgatt ttatcttgtg tcaatgtccc cgttttatcc
     8761 gtacataaca catcgattgc accaaagttc tggatggcat tcaaattttt gatcactgtt
     8821 ccttttttgg ccatcacact tgctcctttg accaaattcg tcgtaacgat cattggaagc
     8881 atttcaggtg ttagaccaac tgctacagat agtccaaaaa gaaaagcttc tagccaatcc
     8941 ccttttgtaa gcccattgat gacgataact gctggagcca tcaatgacat aaatttgatc
     9001 agtagcatgg atgttttatg gatgcctaat tcaaagcttg attgaattgg tttttcagat
     9061 agcgtttctg ctacatgacc aaatagtgtt tcatttccaa cagaaacaat gattccttcc
     9121 gcacttccac tgatgacatt acttcccata aagacaagat tttcgtaact tgtttcgctt
     9181 tgctgatcgt cttcacatac tttcgcatgc ttttctactg gatagctttc ccctgtcaat
     9241 gctgcttggg aaatgaataa atcctttgcg gacaataaac gcatatccgc tggtatcata
     9301 tcccctgctg aaagccgaac aagatctcca cagacgattt cttccatagg aatctctgtg
     9361 tactttccat tacgttttac agctgccgtt actttcacaa gtgatttcag tttttcagcc
     9421 gcttgattgg aacgtacgga ctgaatcaac gtcattgtcc cgctgacgat aaccatagtg
     9481 aagataatgg ctacaccgaa aagatcttta tctccaggag ctgctaatac atattccgtg
     9541 atgaatgaaa taattcctaa tgcgatcaac actaatgtaa atggcgtgat gtatgctttc
     9601 aatatttcta caatgaatgg tgtttttttg ccatatgaaa tcgcattttc accgtaattt
     9661 tctcttgaac gttcgatttg ttcttctgtc aatccatttg ctgatgcatg gaatagttca
     9721 aataattctt gtttcgtttt tccagcaaaa gctgcataga ttttttgtgt atctttcttt
     9781 ttttccatct caatctctcc tttgtgtcca aaagacagct gttctcgctg cttttggtct
     9841 ttagctattc atcggatcga tagagaaaaa actgaaaggg gctgagaaca gatagataat
     9901 agccctggcc tttcctctag atccttgttt ttcgaatgac tgtcatccat ttgttctcat
     9961 ctcctttact aagtaatttt aattcatgac ttccaatcat ttttcgaata gttatttttc
    10021 caattagacc acctcctttt tatttttcac cgatggggat ttgcggcaac aaaaaaacct
    10081 ctcgccaaat actcagcgaa aggtttgaaa aagcatatta aaaaaagctt ctcagatctc
    10141 atcgttgagt tttgacactg tacaacgtaa aaagcagata cctgctttta gctaccttat
    10201 gaaaagcctt atctcgacaa ttcctgttct acccattggc gtctctcgac gtttttgggc
    10261 agtagcctat gtttgtatag gagcctcacc taacaaatct tattcggttt tccttcgtta
    10321 atataacaac taaaaaagag gatgtcaaat caattttcca tgtttttcat acttttttta
    10381 aaatacacac gttatattcc tgtctcacgc ggttttattt gtctcatttt ccacctcccg
    10441 ctataataga aatatagtag gaaacgaggt gctgttatgg aaagaacact tgttattatc
    10501 aagccagacg gcgtgagacg ccatttagtc ggaagcatca tccaacgttt tgaagcaaag
    10561 ggactggcca ttgctgaaat gaagtttgaa actatgactc ctgaattagc aaaagaacat
    10621 tatcagcact tgactgagcg cagttttttt gatgaactga tcgattacat gacttccggt
    10681 cctgtcgttt atcttgtgct ggtcggcgag gaagtgatcg atatcgtccg taagatggtt
    10741 ggagcaacaa aagctgccga tgctgttcca ggtacgatcc gaggagacta cgcgctgccg
    10801 gggactgaaa acatcattca cgcttctgat tcccgtgatg ctgcggtaaa agagatcgcc
    10861 cgctttttcc cgccattcga tataaacaaa ccgtctgaaa aagcggcgaa gtgatacaaa
    10921 ttctaaactg ctggtctagt tgctgggttc agcaatggcc agcagttttt tctctaagga
    10981 cctccgttga ttctttccta acatatattc gagcactgtg aagaattctt ggtagtcttt
    11041 cgtcttttct tcccctaaag cagcagaaat caatctttga taataatctg ccatcaatgt
    11101 ttcatagatc actgtacttc tttctttatg tgctaagctc cgtttcatat cttcattcac
    11161 actacgtgcc tttttcaacc gaccattttc tatataaaac gaagtcaggt tcattaaaaa
    11221 agtaaagaga tactgctcat gattgttcaa ctgtgctaat cgtcgcattc tttttttgat
    11281 tttcaaataa ttgttctcaa tgaaccgatc actgaatatc caaggaaaat cagctagaat
    11341 agatagttca aattgaccat agtctggtat ctgcatcaag tattcttcaa tgattcggca
    11401 ttcataacgt aaaaattcaa attctgtctc agatacttct gttttttcga ccatgtgaag
    11461 attcaaaacc aaataataca gatcttctgt tttcttaaaa tgcctacggt tattgctgat
    11521 ctctttataa ggatcaaagc tgtcttcttg tacccgatct agcattcgtc tttttttctt
    11581 taactttatt ggttcatcca gctggtttcg catccattca tattctgcaa gtgtcatgtt
    11641 cattcgctct aaaaatgatc tcaatgttac aaatgacatt tttttcactg aatttgtctc
    11701 aatcccgact agagaagtct taaaacagat tccttccgct aattgggact gtgtcaactt
    11761 cttgttgact cgaagtttct tgatcaattc accatcatac ataatagttc tcctttttaa
    11821 tttaaatttt tccacattca ataaatagat acgttaaaaa ggaaaaatac acgaaaaaaa
    11881 taaaaaaatg tttttttcat aaaaaatacc aaccttcaag cattagaatg
//
LOCUS       DAIGUC010000075        11344 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.076, whole genome shotgun sequence.
ACCESSION   DAIGUC010000075 DAIGUC010000000
VERSION     DAIGUC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.076"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(51..878)
                     /locus_tag="NOB46_002457"
     CDS             complement(51..878)
                     /locus_tag="NOB46_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059362.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKFLQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            1444..2679
                     /locus_tag="NOB46_002458"
     CDS             1444..2679
                     /locus_tag="NOB46_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCI1059363.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(3678..3938)
                     /locus_tag="NOB46_002459"
     CDS             complement(3678..3938)
                     /locus_tag="NOB46_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI1059364.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(3965..5266)
                     /locus_tag="NOB46_002460"
     CDS             complement(3965..5266)
                     /locus_tag="NOB46_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059365.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            5701..6660
                     /locus_tag="NOB46_002461"
     CDS             5701..6660
                     /locus_tag="NOB46_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1059366.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            complement(6624..7082)
                     /locus_tag="NOB46_002462"
     CDS             complement(6624..7082)
                     /locus_tag="NOB46_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1059367.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLNFVCQIKLDKSSFVT"
     gene            complement(7095..8426)
                     /locus_tag="NOB46_002463"
     CDS             complement(7095..8426)
                     /locus_tag="NOB46_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HCI1059368.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(8437..9879)
                     /locus_tag="NOB46_002464"
     CDS             complement(8437..9879)
                     /locus_tag="NOB46_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1059369.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(9866..10516)
                     /locus_tag="NOB46_002465"
                     /pseudo
     CDS             complement(9866..10516)
                     /locus_tag="NOB46_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
     gene            complement(10535..>11344)
                     /locus_tag="NOB46_002466"
     CDS             complement(10535..>11344)
                     /locus_tag="NOB46_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1059370.1"
                     /translation="KKLNHNAVLIDDDGIEKIAMGKGIGFSAKVSKPFDVEDADKLFV
                     LDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARISSPLDSNIYITLTDHIYFAIQR
                     KREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHRYQTELGSNEVGFITMHIINAEL
                     GEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLTYHRLMVHIKFLVKRLIYQEETP
                     VENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQENEIIYLAIHLARIY"
BASE COUNT         3685 a         2290 c         1744 g         3625 t
ORIGIN      
        1 ttttttcgaa taaacggtat tcaaatcaga acactgattt cacaaccact ttatttcagg
       61 tcgttttcaa tcacctttac cgcgtaatca tttccgttga aacgcgctat tttttttgcg
      121 tccatatatc tttctaaata atcatcttct cctaattgct tatggcaaga agcaatttca
      181 taaagcaagt attccaatgc ataagtcgat ttatgtttct tattatactc aatacccttc
      241 tcacataatt ggattgcttt atcataatcc tcgattttac ggtaataggt ggcgatatca
      301 taatatacaa tgcagaccat cagattatca aaatcagtct cactcaatat tttaagtgta
      361 cgctccacat aaactttcgc aaaatctaat tctccttttg acaagtagat cattgccacg
      421 tttgcagctg cttgtaagtg atggatatct gtttcggtcg tttgttccaa cacttgatta
      481 aaataaaata atgctgcatc tggttttttc gcataaagat gatcaagcag tccttgataa
      541 aataaaattt gatttaaaag atcagaatta cttacttttt cctgatcgat cgtttgtaaa
      601 aatttataag attcttggta ttttgataca gaattcaatg attgaatctc atttattttt
      661 ttcctgattt tgtcttcttc tgtttctact aatatatcgg agatctcgac attcagcttt
      721 ttgcaaagcg cacttaagat attgatgcct ggcgacatat tcttgttttc gatattgctg
      781 acagttgctt gttcacaaat gccttctgct aattgtactt gtgttaaccc ctttttcttt
      841 cggtattctt ttagtaatgc tccatctact ttaatcaaaa caatttcctt ccctttaaaa
      901 aattatttct cctttatatc atacacaaaa aaaagttcta aacaaccaaa aatgtttaga
      961 acagaataaa aattttaatt ttaaaataat attcaaatta aacaactggc gtatctgctc
     1021 cttgatttct ttttgtgtta tctgaataat tatcgtttac agttataaca catagtgaaa
     1081 attgtcatgg cgagaaagtc taagaatatt tttaaacata actatttctt tcttacgtgt
     1141 ataatgacga cagcacacct atcaattaat ataattattt tattttttta tgttctcatg
     1201 tttattttta atgacacaac ttctcgtatt tatctggcac aacatataaa tcgatcaaaa
     1261 aattgttgcg tgtttttttg aaaattggag tttcaacttg attacaaaat ttaaatttag
     1321 aagttgtgaa aacagcgaga gacagtttaa tattcaaaat atacataggc tactcgaacg
     1381 ctgtgttttt tagtatacta gtaagaaacg aagggataga ctcattccaa taaggaggat
     1441 ttcatgaaga caattctttt tgctcctgca gtattcaatt tagctgagac aacacgaatg
     1501 attgaggttg ccaaagctat gaaagaccgt tattactgtg tattctttgg cttttctaaa
     1561 acttttgctc ctttgatcac agaaagtggc tttgagtatc atttactagc gccgatcctt
     1621 acgaaaaaac aagaagaaca aatcataaaa tttgaccagt tgcgtacact taaaaaccct
     1681 tttaccaaag aaatggttgc ctctcgtatc actagtgaac agagtctgat tgctaagttt
     1741 gagcctcgac tgattgtgac aggttcgaat gtgacaattt ttttatcggc ccgcaataaa
     1801 aagattcctt tagtatatgt taaaccctat gctttgagtg aacctttttt tcaatcagag
     1861 catgcgctga tgccccacga gttacgtttc ttcggccctt taagcaatcc cctttggcac
     1921 tggacaaaaa agcgtatagt aaatacccga tggatcccca atgccttcaa acacgctgca
     1981 caaaaagaaa tgcttccttt accaaaaaca agtttacaaa tgatggatgc tgatctaaat
     2041 ctcatcacaa cgcctaaact atttttggaa gaagaacagc tgccggaaaa ttatcgaatc
     2101 gttggtccaa tttttgctaa gctcagtact tccttgcctg aagaagtgct aacttttata
     2161 cagcgaaagc aacaagaaag aaaacgtatt atctatttcg caatgggtag ttcaggcaat
     2221 ccgcgtatgt tacgcaaaat tttgttcttc ttacaaaaac aaccggatct agcggttatt
     2281 gcacctattg actatctgct tgatgacatt caatctgact cagaagatct tttaataaca
     2341 gaatatctgt ctagtcatct tttgcatgaa ttcattgatt tttcttttat ccacggcggg
     2401 gaagggaccg tccaaactgc ctgtgaatcc ggcaaaccgt ttatcggtgt ggggatgcaa
     2461 tttgagcaaa gctgtaatat tgactattgt gtaaaatacg gaaacgcaat cgccctcaca
     2521 aaaccagtga ctgaaagaaa actgcagatt gctctgcgcg aagtttcttc acccaagatt
     2581 cgtcagcagg cacgcacgct gcaagccgtt tttccaataa atggtccaca acaagcaatt
     2641 caagaaatcg aaaccttcct gagcaaccac ccaatatagt ttcaagtaga aaaagctttt
     2701 ttaatagaga ctcatcagta atttcgctat tcgagaccca gacagtgaaa atacaaaaaa
     2761 agtaaatagt ggattgaaaa gttagagtta cttaaattac ggtgtctaaa aaacacaaaa
     2821 tcatccttaa aataaaagat ctgacgctat ccaaatgagc ataggtagcg tctgccattt
     2881 attcttagtc aaattctttg acacctttct ctggttggat catctcaacg tttcttcaaa
     2941 agaaagacca taataattag gcaaatacat tttcttaaaa tgtgtcatat agatctagaa
     3001 gcatcgcttt gtagagattt gtgccgctag tcccctcaac aattactaaa tcaaatgtag
     3061 gatttaccac tttatctttg ataatcaacc tccctcttct gttgagacaa tgatctcgca
     3121 atccgatgca tactcctata taaactgcca gcaatcccca catattgagt agatcatgtc
     3181 agaatgttct atgtcgtcag caacgataca ctaaaagtca cgttcaccat gactgattgc
     3241 tattcccagc acaattattt ctatacacgt ttcatgattt gaataaacac tcacatcata
     3301 catattacca ttcatacacc atactgcagc ccctactata tggttgtaag ctcccaaatc
     3361 tatatttgac ttgatcactt tggtagtaga tctactaatt ctaaatccat tgctgataaa
     3421 atttccattt tttcctcctt ctttctgcca aaacagttaa aacaataata atctttatgt
     3481 aaaaaagggc tgtgacaaaa gccttgtcac agtcccatat tccgaataaa cggtggtcaa
     3541 aagcttgcat ctgcggtaat aagttcaacc aaacgaaaaa taagccaaca tttcacaaaa
     3601 atttaagaag caattttcgt aaatttcttc ttatttcttg aagctaacca cttctgttac
     3661 aaccactttt agaacattta aagcttcgat gtgacaaacc atctatgctg ctcgatcata
     3721 aaattgatag caaaaattcc acaaagtaca tatgtccccc atgaaaacaa aacattcata
     3781 tgcggtacaa tgatctttgg aagaatcacg atcaaaaatg atgccagtgc ccaaatccat
     3841 cgattgattt gaatatgata tgtagctagc atattcaata taaggtgact agccgttaat
     3901 aaaaagataa aaacaaaaaa taaaatcagc caatacattg tttcccacct tctaaaaacc
     3961 aaacttagac agtctggact tcgttttctc cacgactttg ttcatctgac agcatctttt
     4021 tatcataagc ttttacaaat ggataataga taataaatgc tatcaatgtg ttgatcatga
     4081 tcaagataac aacacgccag tcatttcctg ctgaaagata accgccgatt ggagctggta
     4141 atgtccatgt tggcaaaaca gtaaatctat tgaccatttc taatttgact gcaaaataac
     4201 tgataatagt caaaactaaa ggaactaagt tgaacgggat gaacatgtaa ggattcaaca
     4261 tcataggagc tccaaaaatt atgggctcat tgatattgaa gataccagga ataatagaaa
     4321 aacgaccaac ctctttcaag aattttgatt tacagaagaa tataaacaaa acagatacca
     4381 cgatcgttgc tcctgcacca ccaattgtta ccgtccattg ataaaactgt tcaggagcga
     4441 tatagggtaa ttgggtggca gctgtaccat ctgccaatgc ctttgcattc tcatccaaca
     4501 tgatcagcca cattggacga acaacagccc ctacaatact catgccatgg ataccaaatg
     4561 accacaacaa atggatcaaa aacattggta gtaaaacacc aagcaaatta ttccctaaaa
     4621 tattggttaa aggctcgaat aacgataata aggcagcgtt tacatcaaag cccgcgacgc
     4681 ttcgaatcag ccaagtaatt gttaaaatga ctgcacctgg aatcaatgcc tcaaaactac
     4741 gggcaacagc aggtggcact tgttctggca ttttgatagt aatatttcga tttttaaaga
     4801 aacgatatac ttccactgca aaaatcatag ataagatccc cgcaaacatc ccagatgctc
     4861 ccaaagaact cataggtaag acccagccaa gaggtgcctc ttcaggagtt aaaacgttta
     4921 caggaacttg taacataaag aacgttccta aagataatat accacctgtc acactatcta
     4981 atccatatga tttagctaga tccgaaccca taacaaaagt tgcataaata gccatcaatc
     5041 ccatcgtcat cctaaagggt aaaacaatcg ttgccgaata aggggcaata aattcattcc
     5101 atccaggaaa cggtaaattg ataaagacca taaaaaatgt cccaatcaaa atcaatgaca
     5161 atgttgaaac aaccccatta cgaattgcta ataaatgacg ctgtgtacca atttttgcca
     5221 ttggtgggac aagtttctct tcgacccatt tcatcagctt ttccactaaa accactcctt
     5281 ttcaataaaa tatgaaccat tcattgcatg acaacgcaaa gaatgttcat aactaattat
     5341 ataattaaga aattttattt caatatattc tcttaaataa tcaaatttat ttttaagaat
     5401 cctgaaaata agttttctaa atcataggag caacaaaaaa attcgataat taacaaaaat
     5461 caaaatgatt aaatctagtg attgaaacat atcatttcaa aaaaattttg taaattcacc
     5521 cataaatatc accctattta acttttttca tcgtacacta aaattcaaaa caactatctt
     5581 taatctttac ttcttggttt tgttttcgcc gattgtaaaa ttaagctaga caactaaaaa
     5641 aagtcatttg tgctacactc aaaatagttc cgacgaaaga attataagga gtgagtacaa
     5701 atgacctata accatcttac accaactgaa ctcgtaatga tagaagctta tttcaatcaa
     5761 tcacaacctg tttcaaaagt agccaatctg ttacaacgtt ctcgacaaac tatttataag
     5821 gtctatcgtt ttcttaaatc tggtggaagc gcaatgagct actataaaca atataagaaa
     5881 aacaaacgta actgcggaag acatccgatt gttttacctg atgagcaaca ggaatacatt
     5941 caaaaaaagg ttgttcaagg gtgggctcct gatgtcctta ttggtcgagc agagtttcct
     6001 attgcttgtt cggtacgcac actgtatcga atgtttaaag ataaaacctt tgacactcac
     6061 gatttaccaa tgaagggaaa aagaaaacca aacggtcata aagaaaaaag aggaaaacaa
     6121 gggtttcgcc ggtcaatccg agacagaaag acagactata cccagtttga tcatgaattt
     6181 ggtcacctgg aaggtgacac tatcgtgggt ggaaaacata aaagcgcggt catcacatta
     6241 gttgaacggc tatctaaagt catcattacc ttgaaacccg aaggcagaca ggctaaagac
     6301 attgaaaata ggctgaatca atggtttcgt tgtgtcccaa aaaacttatt taaatccatc
     6361 acatttgatt gtggaaaaga attctcaaat tggaaaaaga ttagtaatac caacgatatt
     6421 tcaatttatt ttgcggatcc aggaacacct tctcaacgag gattgaatga acattcaaat
     6481 ggcttattac gtaaagatgg tttgtataaa gctatggatt ttaatggtgt atctgaaacc
     6541 tttatccaat cggtggcatc gaaacgaaat catattccta gaaaatcatt acactatcgg
     6601 acaccaatgg aagtattttt gagttacgtc acaaaagatg atttgtctaa cttaatttga
     6661 caaacgaaat ttaataaatt tccttcaaaa atgcctggag aaactacaat gatcaccgta
     6721 tctttttgtg cttgctccaa cttcttcaaa tctataatag ctaacagtgt cccttctttt
     6781 acctcctggt tactttcaac ccgtatctga aacggacttc cttcgagttc aactgtatct
     6841 aaacccatat ggatcagtat ttttctgcca gattcacttt cgatcgttat ggcatgtcgg
     6901 gtaggaaata tattatcgat tattccttta actggcgcat ggatatatcc atcatgattc
     6961 gttatagcgt atccaactcc tatcattttt gaagaaaaga cctcgtcttt tactgctgtt
     7021 aatggaataa tttgaccact agctacagct tttagaatgt ttcttgtttt aaagaaatgc
     7081 actttttatc acctctactt taatgctggc caatattttt tgtttacttt gatcatttca
     7141 tctagtattt tttttgcgac tctggcattt ggtacggttt gattcaatgt aaatgcttgt
     7201 aaagcttttt gataagaacc ttcaaagtaa gcatctacta gtaacttctc tactgcaact
     7261 tgtgcctcca tcaatccttt atgaaaatca ctgattggtt ttcttagtgt aattggctcc
     7321 acaccagttg caccaacata tgccggtatt tcaacaactg catctgaccg tagattcgga
     7381 atcgcccctt gattaggaac gattagcata aagcgacgac gatcatcatt caacaaggaa
     7441 atagctatat cgacgatata ttgtccatgc tccccaaaat taaagttcaa tacttcttcc
     7501 acaataccgc ggcgtatttt atcagccatt tctttggtat ttttctctcg tccatccatg
     7561 accatattag cacgtgtata ctctttgtca gtatgctcaa cgaccatatc aggatataag
     7621 taatactcta agtaattatt cgggatatta cttggaaaat ttttcgtgat gactgacatc
     7681 atttgaaagg ttttttgcca agttttatct cctatattaa aatcggcgac ttgcatttct
     7741 tttgttatta gtttttcaat aatctctggc ataatttctc gttgcaattc tttatcataa
     7801 atcgatgtat accagccaaa gtggtttaaa ccataatacg taacgatcca attcttacga
     7861 tcataaccgt aattcactgc aatcgtttct tcaattgaaa tagtcatatc acaggcatta
     7921 atcattttta cattcggata tttacgacga acagcttcag aaacgatcga ctctggattt
     7981 gtataattca aaatccatgc tttgggggca tagtcttgta tatgatcgac aatttccaat
     8041 aaacctttga ttgagcgcat cccataagca aatcctccga gtccacacgt ttcttgtcct
     8101 actaatccat gtttaagtgg aatcttttcg tccttttctc gcatctccaa tcctccaaca
     8161 cgaatttgtg agaaaacaaa atcgcatcct gtaaaagcaa gctttggatc atccgttgca
     8221 cgaatgcgaa tatttgaaaa accttttctt ttcagcataa atttaacaat caagtacata
     8281 tccatatttc tttcttcatc aatatcatat aaacgtattt cagataatgg caaccgtttt
     8341 tcattgttca aaatggcttg aacgattcct ggtgtatacg tactcccgcc tccagctata
     8401 gtgataatct gttttttcat catcatcttt tcctttctat tcttctaata atttattgaa
     8461 ttctgccata acataagtca cttctaagcc gatgataatt tgataatttt tttcagttgg
     8521 tttaatgatc ccgcttatcc ctaattgctt gattcgctgt tcctcgacca tggtgggatc
     8581 cactacctct acccgtaggc gtgtattaca actatagaca tccaggatat tggcttttcc
     8641 tccaaacgct tgtagcattt ttgttgccat atattcataa tttttacttg ctaaccctaa
     8701 ctctgtttct tctaaggtta cttcattgcc aaactctgcc ttagcttcac gtcctaatgt
     8761 ctgaatgttt ctcttattga tcaaataata aaaagtaacg taatacaagg caaaaaagaa
     8821 aattccgatt ggaagaatca aaatagcatt ggtagcgatt cgaaaattga tgagataatc
     8881 aacaatacat gctccgaatg taaaaccaat tcgtatattg aataagtaac agacaatccc
     8941 tgctaaaccg gcaaaaagtg catggatcac gtacaacata ggagaaagaa acatgaaact
     9001 aaattcaaca ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc ttcccatgat
     9061 tcctttgacc atctctttat tttctttata agctgcttta tagatagcta gacatatagc
     9121 tggtatacca aacatcatta ctacaaaaaa aactgataaa aacagtccag cctgaggatc
     9181 tccgttgata aagcgtgtca tctctcctct gaaaacttcc ttgctaggag atgtatagct
     9241 tcctaaatcg taataaatat acgtattcaa cacatggtgc agtccaaagg ggatcagcaa
     9301 acgattcaaa aacataaata tccccacacc taatgctccc atatcaacga gcagttttgc
     9361 aaaattatca atcccaattt ggatgagcgg ccagataaag cccaaaaaaa cagctgcgat
     9421 tgtttgtaga atcatcacca tagtcaatgg gaatttttcg cccgcaaaat aagaaaaaac
     9481 tactggtaat ttttgttctt taaagcgatt atacgtccat gccgctacta aaccggaaat
     9541 aattccacca aaaatcccca tattcacttc tgggtccata atttctaagc cttttttcaa
     9601 ggtagcaatc gctaaaaaac cagtaagtgc aggtattcct ttgtccttat ttttgacaaa
     9661 accgattgca actcctatag caaataagat atccaagttt ccaaaaacgg catttccagc
     9721 tgcaccaatt actgggatgt tcagcatatc gtcagctgat aaacgcatga tcaatcccgc
     9781 taatggcatc gctgcaactg gaagtagcat cgctcttcca agcttctgca catttgattt
     9841 aacattcatt tttattcctc ctctattaaa tatcctcata tgttactaac tcaatcaaag
     9901 gatcattttt cactttttga gcaaatgctg aatgaattaa aaattcgact tggtgggtac
     9961 gaggatacac aaaacttgaa ccatttaaca attcctgatc caaatacgct gcgtgacaca
    10021 tgacttcgat cgttttatct tctctcaata tcatgagtaa acttgccaaa tattcttcca
    10081 cactcgtatt gatttgtcgt tttttttcat cagtttctcc tacgacatcg aaacaaggct
    10141 caaaataatc gacatgacga acttcatctt ttcgttcaaa gttgctccga accggcaaat
    10201 catatttttt tgctaatgta acaactacct cctgattttc atccaaagta tgagtatgat
    10261 gatgactgtc taaatgagtt ggtatgatcc ccgcatgata aattttttga atctgagcat
    10321 tccattcctg atacagttga tctttgtcaa tgttaaatgg atgctgataa taagataagg
    10381 atctgaactc tccgctttcg ataagagtat cgacagtttt gaggagtggt ttgccacacg
    10441 tcaatgttaa atggactcct acacctagcc taggcatttc ctttcttagt ttcacagcat
    10501 gctcgaaacc cggcatgata gttacgccct tattttaata gattcttgct agatgaattg
    10561 ccaaatagat gatttcattt tcttgaatgg caagttgaaa ttgctgttcg atgatatctt
    10621 taatctttag tgctgtacaa tacgctttgc tatgtttaaa tgtttcagta aaaaaaccaa
    10681 tattttctac tggcgtttct tcctgataaa tcaagcgttt aaccaggaat ttgatatgaa
    10741 ccattaagcg atgataagtc agtgattctt tatcataaac gtttgaatag gatttttcta
    10801 gatgggacaa aatcgtggtc gtcatttcta ctatttttaa gctctttaaa ctattaggct
    10861 ctcctagctc agcattaatg atatgcatag tgatgaatcc tacttcattt gaccctaact
    10921 cggtttgata tcgatgattg attcgctcga ccacttctac tgctatatca tattcatttg
    10981 gataaaggaa tctcatttct ggcaacataa ttgctgtgac atctctatct tctctttttc
    11041 gttgaatagc aaaataaata tgatctgtca atgtaatata gatatttgaa tctaatggag
    11101 aggagatcct agctgttatc agttcaatca cttcttccgc aaaatccata aattcgattg
    11161 gaatctgcga gactatctca ctgaatcgtt tgatcttttc tttagaatct aatacaaata
    11221 atttgtcagc atcctcaaca tcaaatggct tactcacttt agcagaaaag ccaatccctt
    11281 tccccatcgc aattttttct attccatcgt catcgatcaa tacagcatta tgattcagct
    11341 tttt
//
LOCUS       DAIGUC010000076        11253 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.077, whole genome shotgun sequence.
ACCESSION   DAIGUC010000076 DAIGUC010000000
VERSION     DAIGUC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.077"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOB46_002467"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOB46_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCI1059371.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOB46_002468"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOB46_002468"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCI1059372.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="NOB46_002469"
     CDS             complement(2169..2906)
                     /locus_tag="NOB46_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI1059373.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="NOB46_002470"
     CDS             complement(2997..3524)
                     /locus_tag="NOB46_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059374.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="NOB46_002471"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="NOB46_002471"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCI1059375.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="NOB46_002472"
     CDS             complement(4401..4886)
                     /locus_tag="NOB46_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCI1059376.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="NOB46_002473"
     CDS             complement(5039..5236)
                     /locus_tag="NOB46_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059377.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOB46_002474"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOB46_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HCI1059378.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOB46_002475"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOB46_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HCI1059379.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="NOB46_002476"
     CDS             9211..9423
                     /locus_tag="NOB46_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HCI1059380.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="NOB46_002477"
     CDS             9425..11104
                     /locus_tag="NOB46_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI1059381.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3588 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaa
//
LOCUS       DAIGUC010000077        10801 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.078, whole genome shotgun sequence.
ACCESSION   DAIGUC010000077 DAIGUC010000000
VERSION     DAIGUC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.078"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            185..1183
                     /locus_tag="NOB46_002478"
     CDS             185..1183
                     /locus_tag="NOB46_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1059382.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="NOB46_002479"
     CDS             1295..1804
                     /locus_tag="NOB46_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCI1059383.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="NOB46_002480"
     CDS             complement(1833..2492)
                     /locus_tag="NOB46_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCI1059384.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="NOB46_002481"
     CDS             complement(2494..3258)
                     /locus_tag="NOB46_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HCI1059385.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="NOB46_002482"
     CDS             complement(3266..3943)
                     /locus_tag="NOB46_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HCI1059386.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="NOB46_002483"
     CDS             complement(3980..5365)
                     /locus_tag="NOB46_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI1059387.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="NOB46_002484"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="NOB46_002484"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="NOB46_002485"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="NOB46_002485"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCI1059388.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="NOB46_002486"
     CDS             6304..7161
                     /locus_tag="NOB46_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059389.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="NOB46_002487"
     CDS             complement(7242..7577)
                     /locus_tag="NOB46_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059390.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="NOB46_002488"
     CDS             complement(7644..9014)
                     /locus_tag="NOB46_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCI1059391.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="NOB46_002489"
     CDS             complement(9092..9628)
                     /locus_tag="NOB46_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI1059392.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..>10801
                     /locus_tag="NOB46_002490"
     CDS             9937..>10801
                     /locus_tag="NOB46_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059393.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFL"
BASE COUNT         3285 a         2185 c         1753 g         3578 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgcttttg gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 t
//
LOCUS       DAIGUC010000078        10590 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.079, whole genome shotgun sequence.
ACCESSION   DAIGUC010000078 DAIGUC010000000
VERSION     DAIGUC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.079"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            108..311
                     /locus_tag="NOB46_002491"
     CDS             108..311
                     /locus_tag="NOB46_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI1059394.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(412..1074)
                     /locus_tag="NOB46_002492"
     CDS             complement(412..1074)
                     /locus_tag="NOB46_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059395.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(1087..2589)
                     /locus_tag="NOB46_002493"
     CDS             complement(1087..2589)
                     /locus_tag="NOB46_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1059396.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3137..4816
                     /locus_tag="NOB46_002494"
     CDS             3137..4816
                     /locus_tag="NOB46_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI1059397.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            4943..5422
                     /locus_tag="NOB46_002495"
     CDS             4943..5422
                     /locus_tag="NOB46_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HCI1059398.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            5641..6321
                     /locus_tag="NOB46_002496"
     CDS             5641..6321
                     /locus_tag="NOB46_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCI1059399.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            6329..7660
                     /locus_tag="NOB46_002497"
     CDS             6329..7660
                     /locus_tag="NOB46_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI1059400.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            7675..8637
                     /locus_tag="NOB46_002498"
     CDS             7675..8637
                     /locus_tag="NOB46_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HCI1059401.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            8748..9086
                     /locus_tag="NOB46_002499"
     CDS             8748..9086
                     /locus_tag="NOB46_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCI1059402.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            9165..9872
                     /locus_tag="NOB46_002500"
     CDS             9165..9872
                     /locus_tag="NOB46_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCI1059403.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(9975..>10590)
                     /locus_tag="NOB46_002501"
     CDS             complement(9975..>10590)
                     /locus_tag="NOB46_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HCI1059404.1"
                     /translation="STSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVF
                     FELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLI
                     QHLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQH
                     EKISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3392 a         1883 c         2250 g         3065 t
ORIGIN      
        1 acagctctaa ctatcttttt tagaaaacga gcgttctgtt tgtctgtatc tgttgttgat
       61 gttaccctga aggtagatca ataaacaaac taagaggagg aagcacaatg gcagatttaa
      121 aaggacgttc taaagatatg aaagataaag tagtcggtga aggaaaagaa gcatacggca
      181 aagcaacaga cgacaagagc aaagaaacag aagggaaagc acaatcacta ggtgctgaca
      241 tcaaagaaaa agctcgaaat ttaggcgacg aagtcaaaga caagttttct cgaaaagacg
      301 aaaaaaaata aaaaccactt attactaatt gaatcaagca aataaaaaat ccgaaccata
      361 tctgcgagac agatatggtt cggatttttt atttgatcat tatcctgttt tttaaacttc
      421 gattttttga aattttttat tttttagttc aaagacttca tcacagcttt ttgctacttc
      481 aatctcatga gtcacgatga taatacagcg attttgttca tgggcgattt cttggaaaag
      541 tttgacgata tcttgtgaag ttgtttcatc tagatttcca gtaggctcat ccgctacgat
      601 tagttgatgt tcacagcaga tagcacgaac gatagcgact cgctgctgct gacctcccga
      661 aagtttggtc acctgttttt ttgctaatat ttcatcaatt cctacacgag ccagtcgatc
      721 taaagcaact tgtcgataat tctcttgctt ggtcttagtg atttccattg ctgctatgac
      781 gttgtctaga gccgataaat aaggaagcaa gttgtaagct tggaaaataa tcgagacatc
      841 atttttacga taacttctta acccgatttt gttcagtgaa cgatcttgat agtatacctt
      901 tccttctttt ggtgcatcta gtccagaaat aagcgaaaga aaagtcgttt ttccagaacc
      961 acttgctcct aaaatagcgt acatttttcc agcttcgaaa ttcagttcta catctttata
     1021 aagcgcatct tgcggatctt gataccaaaa tcccaattgt tctgtccgta acatcaaatt
     1081 cctcctttag tttaatagga tttttcttgg gtttaatctt aatatcccta tagaagctaa
     1141 aaagacagaa aacagactga ttccaaatgc tactccggct aatagtccca attgtgcagg
     1201 tttgacattg atttccaatt cgctgacttg atcagaaaca gcaaatggat tattcgtggt
     1261 tccttgttga ccatcgcgtt gaccgccttg ttcttgtctg ttacctggca tttgtccacc
     1321 gccaggagct tgctggtttt gtgtcgtggt ttctgtctgt tggtcaagta gctgctgtcc
     1381 cacggcattc gcgacgacgt ttccgctaag cgaagcaact cctaatgcaa gaatcataca
     1441 aatagccact tcggtaaaca attggagaat gattttactt ctggattctc ctaaagatag
     1501 caagacgcct aactcatgcc gacgctcccg aatggtaatc ataatgatca gagtaagtat
     1561 gataataccg gctacagcca ctagtaaaac aacattttta gaaaaacttg ccacgttgtt
     1621 taaaggttcc aacattgact gatacatgga atcatttgat tgtaagctaa atgtatctgt
     1681 gtcgatcagc ttctcagctt ctttgagaaa ctcatccatt ttatctggat cagatagagt
     1741 gtaaatagca gaatctatcg tgttatcgtc agatgtccca tttagttcat ttgcaaaagt
     1801 gtaagaagtg taaagtgtat tcgacggatt catgaagttg aatttcatac ccatactgcc
     1861 gcttgtttcg ctggattcat aaattccttt gatcgtcatt tcataagtgg tatcttcatc
     1921 ttcagtactc gtgattgtga aagtatctcc gactgccagg tcatttgttt ctgctagagt
     1981 agaatcaatg actacattgt ttgtgccttt gtcgctgtca tctattcctt caccatccgt
     2041 gatttttgct gttccatcag aaaaattact attttgtgca gttgctgaca caccactgat
     2101 ttgaaagtct gcttgagtca tttgcggatt cccgcccatt cctccagcag gttcaccgcc
     2161 tgcatcagta gtttctgaac tgtcttcact tgaatcagaa ctagtgatgg cagttattcc
     2221 atcttttgcc atagctgagg cggaactttc aaaggaataa ctctttacat tatctaattc
     2281 agctattttt tccgcgtccg ttaaggaaac tggtgtaaga gaaaaactgc ctggatctgg
     2341 acgttcttca gtggtagaac cgcttgaaga agtttgttcc tgttttttaa atgaagcttc
     2401 tcgattggca cttaaagtca ctgttgctcc aacttctttt tgtgcttgat tcgctgcttc
     2461 ttctgcagcg cttcgaatcg tgaggccagc tagcacaaaa ataagaatgg ctgtgaacac
     2521 ggcaaacaat aacaatgaac gtccccattt tacttttgta cttttccatg cacgtttcat
     2581 aaaattcata ttttgcatcc ctcctagtag atgcatttga taatagacaa cctatcttaa
     2641 agctagctta aatcttatgc tgtttgcaca ccatcaacat gaggttctgt atatataaaa
     2701 agtcactata gttattgcaa aaaatgtggt aaaatgaaaa aagtatgttt caaaccgacg
     2761 aagaagaaat gaaagaggaa tagcaaaaga aatcctagat gctacagagg gatttttacg
     2821 tgcatagttg ttctaacaat tgctgatact agcgatttag tttatttgtt gtataataat
     2881 ggggaacagc tgaatactta tataagtatt ctggctatag cgtttcgcaa aagatccatt
     2941 ttgttaatga agtatatcca aaataaaatg cccatccaac tgtcagaacg cggatgtgct
     3001 ggtaattttc ctgctgattc tccataagtt gagaaatagt gattttgcat atgcttcatt
     3061 ggaatggctc atatatttag ataaagaaga aaatcgacat ctttaaactt ggatgtcata
     3121 agaagaggtg aagtttgtga gtaccattaa aattatccca ttaggcggcg ttcgtgaaaa
     3181 tggaaaaaac atgtatgtcg cagaagtggg cgaggatatt tttattttag attgtgggct
     3241 aaaatatcct gaaaatgagt tgttggggat cgacgtcgta atccctgatt ttacgtattt
     3301 agaagaaaac attgatcgtg tagctggtgt ctttttaaca catggacatg cagatgcgat
     3361 cggggcactt ccttacttgt tgtcaaaaat ttctgtacca gtattcggga cagagttgac
     3421 gatcgagtta gcaaaattga atgtcagtcg taatgaagca gccaaaggat ttaaggattt
     3481 ccatgtggta gatgagcata cagaaataga ctttggtgaa acagtagtga gctttttccg
     3541 taccactcat acgataccag attcagtggg gatcaatctg aaaacaaaag aaggtagtat
     3601 cgtttatacg ggagatttta aatttgacca aacggctatc ccaatgtatc aaacagatta
     3661 tgcacgattg gcggaaatcg gcaaagaagg agtcttagcc ttactaagtg aatcggcaaa
     3721 tgcagaaaat cctcagcctg tagcttctga agcccaaata gcagatgaag tatttgatac
     3781 gatcaaatat tgggaagggc gtatcatcgt cgcttgtgta gcaagtaatt tgcaacgagt
     3841 gcaacaagta ttggatgcag cagaaaaagc acaacgaaaa gttgtcttga ctggtcaaga
     3901 tttcgaacga attattcgca cagcgatgcg tttagaaaaa cttcaattac caagtgaaga
     3961 tctgcttgtt acgttgaaag acatgaaaaa ctatgatcca gaagaactga tcattttaga
     4021 aactggccga atgggtgaac ccatcaagtc tctgcaaaaa atggcaaacg gtacacaccg
     4081 taatgtcaag attgaagaag gagatttggt ttatatcact actacgccaa gcatcgcgat
     4141 ggaaaccatc gtggcgaaaa cggaagatat catttatcga gctggtggaa cagtgaagtt
     4201 gatctctgag aatatgcgcg tttctggcca tgccaatcct aatgacttgc aattaatgat
     4261 caatttgatg aaaccaacat attttgtgcc agttcaagga gagtatcgtg aattagctgc
     4321 tcatgcagat ttggctcatg cagtagggat gccatacaaa aatatctata ttactggacg
     4381 cggagacgtg ctggaatata agaacaagcg tatgagtgtt gcaggaacta caagtgcaga
     4441 aaatgtaatg attgatggat taggcatagg tgatatcgga aacattgttt tacgtgatcg
     4501 aaaaatcttg tcagaagacg ggattttcgt agcggttgtc actatcagtc ggcgagaaaa
     4561 gaaaatcatt tcaaaacctc aaattacttc acggggattc gtttacgtaa aagctagccg
     4621 tgatctgatg aaagaaagca gcaatatgat tgaaacaatc gttgagaaac atttagaaag
     4681 caatgatttt gagtggagca aattaaagca agacatccga gatcaattag gccgttactt
     4741 atttgaacaa acaaaacgcc gcccagtgat cttgccagtc attatggaag ctactcaacg
     4801 tcgaaataaa aaataaacaa aaagagtaag atgaacctct ctatagagtg ctcgtcttgc
     4861 tctttttttg cgaaaaacaa ataatttttg aatacagcat ccctcgcttt ataataaacg
     4921 atagaataaa gggagtgaat caatgatgag tcaaacaaaa gtcgaacgtt atttagaaga
     4981 acaaaagatc agctatcaac cacttgattt tagtcatgtg gtagaagaat ctttcacaga
     5041 agaactacaa aaaagaggga ttgatccagc tttgatatgt aaaactctcg tagtgaaagg
     5101 aaacaaaact ggggtgatca tcgcattgat tcctttgaac gatcacttag attacaaaaa
     5161 aacgagacaa gtgacgaaag atcgtaaagt tggttttcct ggaatggatt ttgtattaat
     5221 gcatacagga tatccccacg gagcaaacac ccctattgga ataaaactcg cacatcctga
     5281 ttattgtttt ttagcagaca gttctttaaa agaaaaagaa gaagtaattg tgtcaagcgg
     5341 tgaaatcggg agaagccttc ggataaaagt agccgattta gaaaagatcg tccatcctat
     5401 ttacgctgat ttaattagtt aagggacgag aagagaagct aagcagagca gagacctcaa
     5461 acttgagatt atatctgctt ggtacttggt gcatcctgta ttatctgtta caattgcttt
     5521 gtacatactg tactatcaat ccaatgaaaa tatatttagc agctatattt tttcattgat
     5581 gtgcaagtga tgaaatcgtt tttaataaaa aagatacaga gaaaacgcga ggtgtaaaat
     5641 atgaaaatta cgtatcatgg acattcctgt ttaacaattg aaatggaaaa tggccaacgc
     5701 gtgatgattg acccgtttat tacaggaaat ccattgacag acttaactgc agaagaagta
     5761 aagacagatt ggttgctgat tactcatggt catagtgacc acataggaga tatgattcct
     5821 attgcaaaag aaaatcaagc cacaattatc agtattgttg agattgctga ttatgcgaac
     5881 agcagaggag tagattcatt cggtatgaat atcggtggaa aacatgcgtt tccattcggc
     5941 gtggtaaaat tcgtacatgc acagcatagt tcaagctatg aagtagacgg tatcgttcag
     6001 tatatgggcg agcctagcgg aattattatt caagcagaag gaaaaacgat ttatcatgca
     6061 ggggatactg cttatttcag tgatctagga ttgcttgcag aagaattcga tattgatgtc
     6121 gctttcttgc cgattggcga taactatacg atggggccag aagatgcagc aaaggctgcg
     6181 caaacaattc gtgccaagaa agtagttcca atccattaca atactttccc tgtcattgaa
     6241 caagatcccg aatcttttgt agagttactg gaagatagtg aaggaaaaat aatgagcgtc
     6301 tcggaaacgc tggaagtgta ggcagaaaat ggcgacaaaa catgatttga ttttagaata
     6361 tattgaaagt ttacctgttg gcaatcgaat ttctgtaaga agcatcgcaa aagaattgaa
     6421 tgtcagtgaa ggaacagcgt accgtgcaat caaagatgca gaaaatgtcg gactagtttc
     6481 aacaattcaa cgagtaggga ccatccgtat cgaacgcaaa ttaaaaaaac atattgaacg
     6541 tttgacattt ggcgaggtcg tcaggatcat tgaaggggac gttttaggcg gggcggcagg
     6601 attagacaag gtcttgaata aattcgtcat cggcgcgatg actaaacatg ccatggaacg
     6661 ctatattacg ccaggatcac taatgatcgt cggcaaccgg gcggaagtcc aaaaattagc
     6721 attggaagat ggcgccgcag tattgatcac aggaggattc aatacgactg ctgagattgc
     6781 aaagctagct gatgatcttg aaatgccgat cttacgcacc tcttatgata catttacagt
     6841 cgcaaccatg atcaaccgag cgttaagcga ccaattgatc aaaaaagata tcatgcttgt
     6901 cagtgatatc tatatgccag ctgaaaagac tcattatttg cagcagacag atacgatttc
     6961 tgattatcag cgtttgtcag aagaaacgca gcattcgcgt tttccagtcg tcaaccgcca
     7021 tcatcgtttg atggggattg ttacggcaaa agatgtttta gggaaatcgc caaaccagat
     7081 catcgatcgg gtgatgacga aagaaccaat cagtgtaaag aaaacaatga gtattgcctc
     7141 tgttagccat caaatgatct gggatgggct agaagtcatg ccggtcgttt ccgatgactt
     7201 gacattggaa ggcttgatta cccggcaaga tgtaatgaaa gcgatgcagc ttgtccagcg
     7261 acaaccgcag attgcagata cgatttcgga tcagatatct ggaaatatcc atacgattga
     7321 tactgaccgt gaaggaaatc gtttggaaaa ccctaagttc aaattcgtag tagcaccaca
     7381 aatggtcaat ggcgttggaa ccatttcttt tggcgtactt agcgaaatca tttctgatgt
     7441 cgcacaaaaa acaatggtga tgaaccaaaa acgaaatatc ttgattgaac aagtgaacct
     7501 acattatttg cggctgatcc aattggaaag cgaattagac attcgtccac gtgtattgga
     7561 aatcggcaga cgttccgcta aactggatat cgaagtgttt attgaaaaca ccatcgtttc
     7621 caaagcaatc gttgtttgtc aagtaatgga acgttcttag aaagcaggag tgaaatgaca
     7681 gtacagcaag aaatagtaga tacaataaaa aaatacgata aaatcattat ccacaggcat
     7741 ttgcgccctg atcctgatgc attaggatca caagtaggat tagccgaact attacgggaa
     7801 agtttcccag aaaaagaaat acgtcaagta ggtgaaacga ttgaagggct tcgcttttta
     7861 gcagaaatgc aagaagttga agatgtcttc taccaaggag cgctagtcat cgtgactgat
     7921 acagctaatt cacccagaat cagtgatcaa agatatcagt tggcagaaaa actgatcaaa
     7981 atcgaccatc atcccaatga tgacccttat ggagatcttg tgtgggtaaa tacaaaagca
     8041 agtagctgta gtgagatgat tgcagaattt gctttgatgt ttcctgaatc tttaaagatg
     8101 aacgttaagg ctgcacggtt actttatgca ggaatcgtcg gagatacagg gcgctttttg
     8161 tatccctcca cgacgtcccg tacattagag attgcttcga tattgagaaa ttatccattt
     8221 gatgcaagtg ctttgaacag agagattgaa caaatgccga tgaaagtcgc taaactttcc
     8281 ggttatcttt atcaaaatat ccaggtggat gaaaatggtg caggaagaat aatccttccg
     8341 caagaaattc ttgataaata tggaatcgat gattcagaga cagcttcgat cgtttcactt
     8401 cctggagtga ttgacgaagt gctggcttgg gggatttttg ttcagcagcc ttcagggtat
     8461 taccgcgtac gtttacgttc taaggggccg atcatcaatg aattggctaa acgccatcat
     8521 ggaggaggcc atccattagc aagtggtgcg aatgcaaaag atttagcaga agtagaggaa
     8581 atctataaag agatccaaga tatatgccaa tcgtataaga gcagaaaaac agaatgatac
     8641 ttcgttcgaa aacgtgcctt ttgtagtaaa aatcacaaat gtatcttttc aagatcttct
     8701 ttttccgtta caatagtgct cactaaagat tttaaaggag aaagaagatg acattaccaa
     8761 attgcccaga atgtggctca gagtacacat atgaagatcg aggcttgttg atttgcccag
     8821 aatgcgggaa cgaatggaac aaagaagaac aagaaactgt catagaagac ggattagtgg
     8881 tattagatgc aaatggaaac cgtctgttag agggcgatag cgtgacagtg attaaagact
     8941 tgaaagtaaa aggtgcgtca ggtgccatta aacaaggaac aaaagtcaag aacatccgtt
     9001 tagtagaagg cgatcataat atcgattgca aggtagaagg atttggaccg atgaaactga
     9061 aatcggaatt tgtgaaaaag aattaaagaa tattcaaggt cttttcacat tcttttccta
     9121 ctactaatga taaaataaag taaacgaaaa ggagtgaaac gaaaatgtat ggttatggaa
     9181 tgtatggttt tttagatccg acatttcttt tggtcattct tggattagtt atttccggaa
     9241 ttgcgtcagc gtacgtcaat agtactttcc gaaaatacga tcaagtgaga agcaaaaaca
     9301 atgtgactgg tacacaagca gcacaatata tattacaaag tcaacagata aataatgtcg
     9361 gtgttcaaca aattgccgga gatctcacag ataactacaa ttcaggtaat aagatgttga
     9421 gtttgtctca agcaactgca cagtctactt cagttgctgc gataggtgta gcagctcatg
     9481 aatgcggaca tgcggtacaa gatgcttcgg gttatgtccc attgaagatt cgtgcagcac
     9541 ttgttccagc agctaacttt ggttcgatga tttcgttccc cttgattatg gtaggtgtat
     9601 tgcttagctg gaactctacg ttaatcaata tcgggatttt cgctttttct ttagcattac
     9661 ttttccaatt ggtgacatta ccagtcgaat ttaacgcgtc tcggcgagca atccaaattt
     9721 tgagtgaagg cggactactg acggaagaag aagtaccgat ggcaagacac gtattatttg
     9781 cagcagcact gacttatgtt gcagcagcgc tttcgacatt cctgcagctg ttgcgcttga
     9841 tcttattgtt cggcggcaac cgaagagatt aaaataaaga agttgtgaaa tcagcgcttt
     9901 gatctgagct aataccgaga gttagctgat tgaataccat ttatttggaa taagaggatg
     9961 tgacaagaat tttgtcacat cctctttgtt ttgttctcat aacctttttt catatacagt
    10021 tcatgaaccg cttttattaa cttgccaaat aacactgtat tgtgcgttgt atccagatag
    10081 aaagtctccg tttcatctga aattttctca tgctgatctg taatgatcaa atcagcatgt
    10141 tctgaatatg cggtaatttt aacagcatct ttgcgaaata actgctgcaa atggctttga
    10201 agatgataat ttcctgtaaa ctgtttggtt atctgcaaat ggatgagtaa ctgctctttc
    10261 gtttctgttt gtagtaagtg ttggatcaat tgactaaggt attgactgat ttggtttctt
    10321 tccccatttt ttgaaaaaat tgtatcgatt ttttctctta atttcttttc ctgtataaaa
    10381 gaactagaat gattggacgt ggcttctgga aagcaaagtg tagaaaaact actgctggat
    10441 tcacccaaca gttcgaaaaa aacaactgcc aacacaagaa aataaaaata aattggtatt
    10501 ttattttcta aatggttgag aggaaactgt tgagttaagt aagtcatcaa ttgaccgact
    10561 tgtcgacaaa taaggttttt gcttgtggaa
//
LOCUS       DAIGUC010000079        10123 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.080, whole genome shotgun sequence.
ACCESSION   DAIGUC010000079 DAIGUC010000000
VERSION     DAIGUC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.080"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(561..1601)
                     /locus_tag="NOB46_002502"
     CDS             complement(561..1601)
                     /locus_tag="NOB46_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI1059405.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1950..2276)
                     /locus_tag="NOB46_002503"
     CDS             complement(1950..2276)
                     /locus_tag="NOB46_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059406.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2263..3066)
                     /locus_tag="NOB46_002504"
     CDS             complement(2263..3066)
                     /locus_tag="NOB46_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1059407.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3419..3709)
                     /locus_tag="NOB46_002505"
     CDS             complement(3419..3709)
                     /locus_tag="NOB46_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI1059408.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3845..4024)
                     /locus_tag="NOB46_002506"
     CDS             complement(3845..4024)
                     /locus_tag="NOB46_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059409.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4021..4371)
                     /locus_tag="NOB46_002507"
     CDS             complement(4021..4371)
                     /locus_tag="NOB46_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059410.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4364..5689)
                     /locus_tag="NOB46_002508"
     CDS             complement(4364..5689)
                     /locus_tag="NOB46_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI1059411.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6139..6753
                     /locus_tag="NOB46_002509"
     CDS             6139..6753
                     /locus_tag="NOB46_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1059412.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6918..7742)
                     /locus_tag="NOB46_002510"
     CDS             complement(6918..7742)
                     /locus_tag="NOB46_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059413.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(8379..8636)
                     /locus_tag="NOB46_002511"
     CDS             complement(8379..8636)
                     /locus_tag="NOB46_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI1059414.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8629..8898)
                     /locus_tag="NOB46_002512"
     CDS             complement(8629..8898)
                     /locus_tag="NOB46_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1059415.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9029..9208)
                     /locus_tag="NOB46_002513"
     CDS             complement(9029..9208)
                     /locus_tag="NOB46_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059416.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(9589..>10123)
                     /locus_tag="NOB46_002514"
     CDS             complement(9589..>10123)
                     /locus_tag="NOB46_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059417.1"
                     /translation="QTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
BASE COUNT         3098 a         1842 c         1454 g         3729 t
ORIGIN      
        1 tccgttgcgg gtaataccgt aacactgaag ggcacgcatt aaggcgtcat cttaatgctt
       61 tcctgtagga cactgacgga gattaccagt ctcccgagcc ttacaggggc ctttcttttt
      121 tttgtatttt caattatcac aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc
      181 acaagcatat cagacaatta aatttaaaac aactaaaaat atacaaaaaa gtgtaattga
      241 atattagcag cactgcctga aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt
      301 gaattacctc tcttcatgaa ttattataac tcaaaaaagc acatatgcaa acactagttc
      361 cctatttttt tgaatgaaaa ataactaaaa tatctaacga ttatgacttt aaaacctacg
      421 tttgtgattg ttttcataaa cttttaatct aaaaactccg gaataatagc tatttatttg
      481 taacatttgt aataaaatta aaatcataaa aaagttctaa tttaaaattg atcattttta
      541 tagtgatcgc tttttatcaa ctactctagc caattttccg tactaactgt tggtaattcg
      601 ttaaatgttt ctctttgttc gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa
      661 ttttttacat aaacgaaaat tagattctgc aaattgttta ctttttcagt tttttgtttt
      721 tgataagctt tcagcaaagt catatataat cctttgtcag catcaattcc ataagattcc
      781 agttcttcat aaacaacaac tgtttgctct aattcttcag cttttttctt tgcattatga
      841 atagtttgga cggttttttg agcgtcttcg taagtactag aaaatgtttt tatcaagttt
      901 aatacatttt ctggtacaaa tgtatttata ctgtcctctt tcatgatgtc gacgaagtta
      961 tctagtaaaa cttgattttg taactgatca gtttcagtgt ctattatgtg tctattagtg
     1021 tctatagaat tagaatagaa tagattgtct gcgattttcg caattacggt tgagtccttg
     1081 atatgactgg attttgccgt atttgcgatt ttcgcaatta cggtggtatc attgatttct
     1141 cgcggttttg ccgtatttgc gattttcgca attacggtgg tatcagtatt gtcttcctct
     1201 tccatgattt taaagacgtc ttgattcgtt acttctggct tgcctaagta caataaatta
     1261 ggcatggatt caatcttacc gtcacgttta tttactcttc ctctcttctg tttcagaaga
     1321 cctgcttttt ctaattcctt tttgatttta gatactttac cttcgcggca ttgtaacaat
     1381 ttcattaatt cttcaactgt gaatatgaaa aatatattat catcagaatc tacccagtta
     1441 tttttgactg aataatcaaa tcgatcttta agtagcatat aagcaatttt tgcatcattt
     1501 gatagatcca tgtatttttc gttagtaaaa aataccttag gcatttgata atatttttca
     1561 cgataaattt cttttgattt gtaataatta aaatcattca tagccaatcc tctttctgta
     1621 ggatagcgtt ttgttcaaaa ctatgttaca atgaattaaa caaatatatc tatccactat
     1681 atatttttct actgctgata agtcgccaaa ctttgttaaa gcagtagtct ttttttatct
     1741 ttttttagtt taccttaaaa aataaattaa agcaaaccgc tctatttcaa ggtttaagct
     1801 catagtaact atatcacgat attacaataa tattatatca cgatatcgta atattacaat
     1861 atgaagataa gcgacttatc agctttgata ctactgattt ttataaaaaa aatatcacga
     1921 tattatgata tcgtgatatt gaatgtaaat taaattttat tttgtttctt tgctagttta
     1981 tatccttcaa tcaagtattc ttcaggtatg gactttaata gcgcatcttc tataacgtct
     2041 ggtttacttt tgtctgattc agcaatagtc gtccaatatt tgagtgctga cattagaatt
     2101 ggatttatac gaatgctatc tgctgttctt acactacttc cttgatcttt tatgacttta
     2161 cttatatttt tcttggttaa ttcgatttct tctacttctt ttgatttaaa attcttttta
     2221 tttttatttc ctagtaatct acttactgca gcttgactgc gattatcttc tgccatcaaa
     2281 atcaccaact tcttttaaat attcttctgt aaatgcttta tagtcatctt cagctgttga
     2341 gggtttatta aaattgatta gatctgatcc agcagcttgc gcttcgtcaa cggttattgt
     2401 cctacgaata taagttttga aaatttttgc accaatgact ctagaaattt cggttgctgc
     2461 agacgtcatt tctttagaaa tgttataacg cttattatac ttagtaaata gaactcctcg
     2521 tacttcaagc ttgtcgttcg tatattcttt taccgtttca atagtttcac ttaactttat
     2581 tagtcctttt aatgagaaat acgcagcttc aactggaatg ataatttcat cagaaacagt
     2641 aaatgcgttg actgtaagca ttcctaaact tggtggacaa tcaattataa tataatcata
     2701 gttgtccttg attggttgaa gtactctttt aagcctgtgt tcacttccta cttgagtaaa
     2761 ttccctctct gcagaagaaa gggctatgtc ggctggcaaa acatcaattc ctttatagtc
     2821 cagaatagca tctgtaatgt cagcctcccc ttttaatact tcataaattg taggttggtt
     2881 tgttccatct atatcgaaac ctacattatc tgtagcattt ccctgaggat caatgtccac
     2941 taaaagtaca tttttaccgt aaacaaattt caaacatgct gctaaattaa cgctagtcgt
     3001 agttttagaa actccacctt tttgattggc tactgacaat attcttgcca ttaaaatatc
     3061 ccccattcat cttatattat aatataatta tatcataata ttgtgatatt gcaatatcgt
     3121 atatgcatta tattgtaata ttgtgtgatt attttgtttt aaagatatat atcggttcgg
     3181 atataaagat tattcatatg ttattcgaaa ttaaaataat cactttttat tactttaaaa
     3241 ttttttatta atgataagaa atatgttttg cgagcagcaa ctagaataat ttaaacatta
     3301 ctaaactgtc tatattgtta ctaataattc ccttcttata gtgcattttc ttagaaaaaa
     3361 acaatattac gatatcatga tattaagata tcgtaatatt atacaattgt gattgatatt
     3421 atatatgttt ttttattttt ttatcatgtt taatcttgaa ggaatcatat tctttttcta
     3481 aagacaggag cttttcataa acatcagaca tgtttaaact agaggccagg cttaaatcat
     3541 aaacgaatga agcaggtaat gattttattc tacgttgtcg ggttatccag cttgcaaccg
     3601 ttccttgtgg gtaggcatat aactcacaaa attgttctac agtgattcct aaattcttga
     3661 taatgtaaac attgatcggg tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc
     3721 ctactttctt ttattattgc gtttgcaata atagtttaac acacgcatta ttctagtatc
     3781 tactcctatt tgtaaaaaca aaaaaggatt catagagata actctataga atccgtaaaa
     3841 taccttatat atataacggg aagatataaa acctaaaatt atgataacct gctgcagctt
     3901 ctacatagaa agagaagcgc tcaacaccaa cctcatttat caaacgttgg ccataacccc
     3961 aaatctcttc tgatagctga tcaaaggtta tatactttag ctcatattgc tggataatgt
     4021 tcattctaat cgactccatt tattatcctg gtaaaattcg atatgacgta tttcgtcgta
     4081 gtgaattttg tcttttccaa cgtagatccc cagctcatca ctacctaaga tcttgccaat
     4141 gatatcttct ggatagtatc cttcagcgtt tcgttcttct ttttgaatag atactgatct
     4201 attttttatg actgcagcgt tcaatacttc cgcaatctct tcagtcgtca tttgttcttt
     4261 tgctaaattt tgactggttc gttgttcatt gtcggcatca atttcttcag tatgatcaga
     4321 taaataaaac cctgcccact ttaaacgtcc acgatcattg taatcaatca tttttaattc
     4381 ccccatttcc gcccgcatga ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt
     4441 ctaacattga agaagcatgt acaatcgacg taaaaccata tttttgccga atcttgtcaa
     4501 taattttatc taaattttct tcgtcaattt gcttttgtgg atcactaaat aaatccagct
     4561 gaagcgaatc ggtgtacaca agcttgctat aggttattcc aacgtgcctt acttcttgtc
     4621 cttcataata cttatcaaac aagaaaagac aataattctg caattccttt gtattatctg
     4681 tgataggtat tttcatctgg tgtgaaaatc ctggtctcgt ttctaagatc gacgtaccaa
     4741 tgtttaaatg aacacatcct gttttacaat tatgctgcct gatacgaatg gctacttgtt
     4801 ccgccatttc ttttaccacc agctcgattt catttcttct agtataatct cgtggtaaca
     4861 cttgtgaatt accataagat ttttcctttg tcggttctgg cgggattgct atatctgttc
     4921 gatcgattcc gttagcatgg aagtacagct gtaatccaat cacacctaat ctattcttaa
     4981 tcgtataagg attccagtta gcaaggtctc taatgctcaa aattcccatt tggttgagcc
     5041 tttttttcat tcgcgaacca attccccaaa agtccgtcat ttcgggaata ttccatactt
     5101 tctcaggaac gttttcgtac gtccattccg caataaatcc ttcattatgc tttgcttcat
     5161 tgtctaaggc taatttagcc aaaaggggat tatcgccgac gcctaccgta gcaatcaaac
     5221 ctaactcttc tttaatacgt tcttggatca tttgagcgag cttcttcctt cgctgacttc
     5281 gtgtttcttc agtcgtaaaa agattcagtg attttgtcac ttttaaaatc gattcatcga
     5341 tcgagtaaat cagtagatct tcatcagcca catatcttct gaaaatatta tttacctgca
     5401 tatttcgctt gatatatagg ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg
     5461 gttgtggtaa gtcacgtggt ctactcacat ttgtaatacc ataccgcttt tttgcttcag
     5521 gagaagaagc taatatcaat cctgaaccag tattatcaga tcgactcata acaacaagtt
     5581 ctgttgttaa tggatctaaa tttctttcta tacattcgac acttgcgtaa aagcttttca
     5641 tatcgattaa aaagtaatca tttactggct cttttgaata atccatcata aataacactc
     5701 cattcttcca cattatacaa acatatgttc gatgttgtaa agaagaaata gctaaataca
     5761 taaaaaaaga agcataggta tgctatcacc ctgcttcttc ttttgatttg tatgatcaat
     5821 ttgttctatc actttactaa ttaatttgaa aatctaataa aaactctcac tctaaaagag
     5881 tgagagactg caaattagag tacggacttt tttggagttc cgttctttaa tattaacaaa
     5941 tgaataaaat ccttacaaca tttgagaata agttatcagt agacacttac aaaaaattct
     6001 catactattt cctccatcat tagtttttgt ctatataagg tttaccctaa atagacactg
     6061 gtataacatt gaaaaatatg gcttcctcgt gtatgattag ggtgtatttt aaatagttgc
     6121 agaaagtagg taaaagtttt gagagttgca tacatacgtg tctcatcgat cgatcaaaat
     6181 gaacaacgcc agattgaaga aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa
     6241 caatctggcg caacgattac tcatcgacct gttttccaag aagcattaga ttacgtccga
     6301 gatcaagata tttttattgt ggaagctatt gatcgacttg gaagaaatta tgacgagatc
     6361 atcgcttcag tcaattactt gaagaagaaa aatgtgaagc tgatcattac tagtttaccg
     6421 atcatggctg aagcaattgg caatcctctc ctggataaat tcattaagga tctgatcatc
     6481 caaattttgg ccatgatcgc tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa
     6541 ggaattaaga tcgcaaaagc aaacggcgtc tacaaagggc ggcccaaatt atacagtgca
     6601 gacgcaaaag atccccaacg tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat
     6661 ggtgttgcga ttgctaagat tgctaaagac tacaatgtta cgagacaaac cgtgtataga
     6721 ataaaaaaag acagcatggt caatgacaaa tagttgatca tgctgctttt attatcttct
     6781 catctttaat ttcctacata taattactat ctataaaatt aagtcttact cagaacagat
     6841 aaagcataaa attccaacaa accatttttt acttaactaa ataaagagtc tgttaatata
     6901 atcttcactt atttacgtta atcccctact gtatttgttg gttccttatc tatattttct
     6961 acaaaatcct tattatcttg tgatttagct tcgtataatt ctttgtatgt cgacacattg
     7021 gttatactaa ttcctatagc tagttcttga gactctactt ttctctctag ctcctttgac
     7081 aaagtgattt gagatttatt tggttccgtt ggagtcaatt ctatagattc ttcataaaaa
     7141 tctctataca taaagctatc attaatttta taaaaaaaat taaatgtttt tagcactgcc
     7201 atataacatt caaaacattc ttctatagtt ggtttacttc cttgaggaga atgaaccaat
     7261 ttattacgtt tttctatgaa atttttaatt tcctttctta tttctttcgg aaactcaata
     7321 ttaaagtacc ctttaaacat gctccctaat aatttgtcta cagggggaga ttgtaaattc
     7381 tcaaatatta gagttaaatc aggtttctct tgttgataaa attcctttac ccctatttca
     7441 caggctgtaa ttatcgaaat aaacctatct ctagtatttg atatattttt acttctttta
     7501 aggagtataa gagaaaaggg gatactttcg tgtccatgca tgtaattaac taattgttga
     7561 gcttcagaag ttatatctct aattatatag ttaacggaat taggaagtgt ctttaactct
     7621 aatgaaattt ctatccaatt actatcttct aatctgtata tgctcgaagt ataatttgat
     7681 tcgtcagcaa gcatcgctac atcccaaaca ctgatcataa aatcttttaa acgttcaatc
     7741 atttcagcaa tattgctaaa atcagctaat ttttctttag aataaaaaaa acatttatat
     7801 cagaatcaat aaattctatt tttttattac tatatcgtca tcattatctt gaccatttat
     7861 gtttattgtt ccctgagtgg ggagtacttc tttcaaattc aagttaaatt tatattccat
     7921 tacttctcct ccaatatata aaaattactt aactgtatcc aaatttaata tgtaaataaa
     7981 tcattaattt ttagctaaat tctatgagaa gtttattttt gttgtttttg ctaattaact
     8041 aaaactagta caaaaaattt aaaatagatt attaaaccta ttgcttattc tattcagtca
     8101 tatatataag cgtcatcctt tagtaactaa catcccacac tacaatagta ttataacata
     8161 tctattcaac ttcaaattgt tgaaatttaa gccatttata tttacttttc ctcaacttta
     8221 gaaatgattt tactaacctt atatccgtaa tacgcgtaac aaacacattc attaataaca
     8281 atcaacacta agctatatta gctttttaaa tgactagggt aaataaaata aggatcaaaa
     8341 acttttaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc ttttgcagaa
     8401 taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc tgtaattctt
     8461 ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa tccagcaaag
     8521 ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct tttgtttcct
     8581 tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt aatcatcaga
     8641 ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt catctcctcg
     8701 acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt gcatagaatc
     8761 ataatctctt tttgataata caacaactgt atcttctaca tctttacttg ttacaataag
     8821 tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc ggaaatttga
     8881 ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca attgtacatt
     8941 atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa agtgctatca
     9001 cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc tcaaatcctg
     9061 ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat tcacttttgc
     9121 cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac gtaacgggta
     9181 accgtttatt tcctattgca attggcatta gtactctctc ctttcatcga aataacccta
     9241 tgaaaaatat ggctgcaatc atcttgaata gtagactcac aagggctaat acaaagcgcc
     9301 aaaagatcaa acaaaatacc agtattgcca aaaatactac gaagtttaaa tgcacagctg
     9361 cagcatggcg cataagtatt tcgccaacaa ataggactaa caatagagga atgattttat
     9421 tcatatggat ctccttcttt ctcttaggtt atcgggtgtt gcccgcttat ttcgcaccac
     9481 ctaagcggcg ggggcggttg gagcgattgg tgcgaaataa gaaccattcc cttagttact
     9541 aggttttttg tccttatttc acacattctc acttttcggt ataaatgatt attgcctttt
     9601 tttcctttca aatcgttgat atggcattcg tttacggtca agttcatttt ggatttcttc
     9661 tgtatcgtcg taagtatagg tgtctaaaaa atcagttaaa gtcgtgtacc agtcgtcgcc
     9721 tgggttatct acttcttcta catattccct caaaaatgct tcgggtacag cgagttcata
     9781 atccattccc attaacacga tagattccgt tccacacgtc aaaaatctag taaatacaag
     9841 gtaataatcg tctatcgtcg catctttgct gtttagctct tccatttctt cttccattaa
     9901 ttccatgctc tcaaaaattg aataatattc tgattctgag taatagtgtt tcctgcaaat
     9961 cgtgtagctg acaaagtttt cgaccagctc actcctttct aggtaaacat tcatgatgta
    10021 tttttctgtt tctagtcgta gaagctccgt tccttttttt accgtttcag gacgacgttt
    10081 atacacgtct aaacgattat ggctgactgt gaccttcgtt tga
//
LOCUS       DAIGUC010000080         9974 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.081, whole genome shotgun sequence.
ACCESSION   DAIGUC010000080 DAIGUC010000000
VERSION     DAIGUC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.081"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            166..360
                     /locus_tag="NOB46_002515"
     CDS             166..360
                     /locus_tag="NOB46_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059418.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            629..928
                     /locus_tag="NOB46_002516"
     CDS             629..928
                     /locus_tag="NOB46_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059419.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1025..1459)
                     /locus_tag="NOB46_002517"
     CDS             complement(1025..1459)
                     /locus_tag="NOB46_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1059420.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1691..2401)
                     /locus_tag="NOB46_002518"
     CDS             complement(1691..2401)
                     /locus_tag="NOB46_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI1059421.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2391..3251)
                     /locus_tag="NOB46_002519"
     CDS             complement(2391..3251)
                     /locus_tag="NOB46_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCI1059422.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3256..3894)
                     /locus_tag="NOB46_002520"
     CDS             complement(3256..3894)
                     /locus_tag="NOB46_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCI1059423.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3909..4208)
                     /locus_tag="NOB46_002521"
     CDS             complement(3909..4208)
                     /locus_tag="NOB46_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1059424.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4251..5735)
                     /locus_tag="NOB46_002522"
     CDS             complement(4251..5735)
                     /locus_tag="NOB46_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI1059425.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5755..6216)
                     /locus_tag="NOB46_002523"
     CDS             complement(5755..6216)
                     /locus_tag="NOB46_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1059426.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6234..7301)
                     /gene="ulaG"
                     /locus_tag="NOB46_002524"
     CDS             complement(6234..7301)
                     /gene="ulaG"
                     /locus_tag="NOB46_002524"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCI1059427.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7519..8289
                     /locus_tag="NOB46_002525"
     CDS             7519..8289
                     /locus_tag="NOB46_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1059428.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            8641..9936
                     /locus_tag="NOB46_002526"
     CDS             8641..9936
                     /locus_tag="NOB46_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1059429.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT         3122 a         2042 c         1633 g         3177 t
ORIGIN      
        1 agaacaatag ccttttatta tatatattat tcaaattagt tatatcgagt gaaaaaaact
       61 ttcaaattga ttctttttat ttatcataaa gatatagata cataatcatt ttcacttaca
      121 tatatttgaa tattaactaa aaacagcaag aaagaagagg atcaaatgta ttatgtagaa
      181 gtaaaaacaa aaggcgtcaa aaacaaacaa tatgtgaaag gtatcagtaa cgaatatcct
      241 ttacttggtt catggaaaga agctgctcct ttttccaaac catgtgccat aaaaataaag
      301 aacgagctag aaaaagaact gacttgtggt aaagctgttg tagatatcat cgaaaagtaa
      361 atccaatgta tagaaaggaa gatcacacat gaaaagcgac gtacaaattg ctaagattat
      421 agaattagaa gaagaagacg cagtgttgac aattgaaaaa aaataaatgt ttgtatacca
      481 tatgattatt tcaatatgta tcctggaatt ggagatctcg tagagctata tcaagatgaa
      541 tcaaatatac ttgtcattca tcatgaaata tagagactta taaaattgtt tatttttata
      601 atgtatcagt atagaaagga aataaaacat ggattatact gttgaatttg acagtgaact
      661 acttaagcaa tttccacaag aagaacattt catgtataaa gaagcaattt cccacaaagt
      721 gacagagtat ttggagcata atttttttcg tataaagcca gtgcgtactc gttcggcaaa
      781 aggaatatac gagatgaaag tcaaaattaa taaaaaaaat tatcgcatag catttgcttt
      841 aaaaaaaaat catgtgttca ttttttatat tagttcgaat ttgcaaaaaa ttgtatttga
      901 taaagaggtg agtaaaaaaa taaaatagct gagcattgga ggatagattg agtgatacta
      961 agtctatcct cttgtttttc taaagaacta agctagaatt ttttcttttg tacgttatta
     1021 tatgttattt gtcattacca aaaagcacct tttttcttct agtatctatg acataagaaa
     1081 taccacccat ttcctttact tgaacaaatc ctactgattc ataaaatttt tttgttttct
     1141 cagtatcatc tgtcaataat tcgatttgga ctggtccata actagtgatc ttctccaaag
     1201 cttcattcaa aagcactttg cctattcctt ggcgctgata cctcggatga atgaggatat
     1261 cttgaataaa tgcgatcgtc gcaaaatcag tgatccaacg aacgattccg ataatcttcc
     1321 cttccccatt acgctttatc agagattcag attgttcaaa tgctctagct aaccttgcag
     1381 tgtcttttgt gtaattcgtc caaccaacgc tcttatataa ttcagaaatc tcatcgatca
     1441 taagggaatc aatattcatt tttttcttcc tttcttatac aattctccct ctaataatac
     1501 agttctttga ctatttaatc tatcacatat aactctcctg taaagattct ctcgattcct
     1561 taaaattcct ctttcctttt agaatgcata ctttttgata aataaaaagg ttgtgataaa
     1621 ttttcttcac aacctctgtt tctctctatc aagtgttatc ttttaatttt ctacccttac
     1681 cctagcatct ctattgcccg tagtatgcat actttccatg tttgcgaaaa taatgtttat
     1741 ctagtaaata ttgcgggatt tcacatatat tggggttgat cagctcgttt tctttggcca
     1801 tcagacaaat ttcatctaag atcaaactgt tttctactgc tttcataggt gaatcccccc
     1861 atgtgaacgg tccatgtcca tagacaagta ctccagggac ttcgtttgga tctaattttc
     1921 tttccttaaa cgtctcgaca atcacattcc ctgtatgaac ttcgtaagct tctcttactt
     1981 cttctttcgt taattggcgt gtacaaggaa ccttaccata aaaagcatca gcatgagtcg
     2041 tgccataagc tggcaaatcg cgtcctgctt gcgcccacat gacggagtgc gtggaatgag
     2101 tatgagtaat agcagttata tcttcaaaag tttgatacaa aacaacatgt gtggggagat
     2161 ctgaagatgg ttttaagcta tcttcttcta ttatatttcc cgacaaatct gttaccacca
     2221 tttgatctgc ttgcatgcat tcatatctga caccgcttgg cttaatgacg atgactccta
     2281 gctcacggtc cacttcactc acattgcccc aagtcaattt gactaatccg tatcgcggca
     2341 atgccagatt tgcttcaagg acacgttgct tcattgctgc aattttttct tcacaagaca
     2401 tcatagccag cctccttcaa tttagaactt aagtagtctt ttgcctgctg gatttctctt
     2461 cgaaagtctt ggcttttttc actccacatt tcaatcagaa atgttccatc ataatctaga
     2521 cgtttcaaat gtcttaataa tccaagaaaa tcaacacaac cgctaccaaa aggaacatca
     2581 cgaaactggc ctgaatattc ttttgttaca gggtaagtat cttttaagtg gatagcagtg
     2641 atataatcga tccctttctc aagttctcga gccggattat tttccggcca tgcggacaaa
     2701 ttgcctaggt ctggatatac ttgtagaaaa ggtgaatgaa tctgttcttt gatttctaaa
     2761 aattttgaaa tggagttcat aaatggatca tccatgattt ccacggaaag aatgatgcca
     2821 tatttagaag cttcctttac gctttctttt attccttcga taaagtcttc tctggaattc
     2881 attgatttct cttcataata aacatcgtat ccagctattt ggattacttt gacgcttaga
     2941 ttatgcgcca aatggattgc ttttttcatt agttgtttcg ctgctttttt cttttctgga
     3001 tcagcagaac caaacggaaa tcgccgatgc gcacttaaac aaatcgaatg gatacgtaca
     3061 ccggagctga acatctcttc tctcagctca gctatctttt cttcagacca atctaatcgt
     3121 gctaaccgct catccgtctc atcaatcgac atctcgataa aatcgaagtc catttctttt
     3181 acaagggaaa aacgttcttt ccatgaaata tctttgggta acgctttttc ataaatccca
     3241 atttgagcca tttccttacc cccagatacg aatgatctca tctttgaagt tttgtgcggc
     3301 cttcatcgga tcatttgctg ctgtaatacc acgaccagtg ataaaggtat acacatcgat
     3361 cccttcaaat aagtgtaatg tgtgtggatt taatccacca gttacagaaa cattaaagcc
     3421 tagttcaatc agttttttga tcttcgataa atctttttca ccccaagttt caccagataa
     3481 cagcgcatca cggctttgat ggtagattac ctgccggata ccgatgttat gccaatccat
     3541 ggcttgttca aaagtccaat tgccgtagag ttctacttgc aattcaccta tttctttttg
     3601 tgctgcctcc atagttggaa tcgttgcaca acaaatgact gtcatccagt ctgctcctgc
     3661 ttttgcaaca ttactcgcca ctgttcctcc agcgtctgca catttcgtat cagcgactag
     3721 ttttttatct gggaacatac tgcgaataca gcgaatcgct ttttgtcctt cctgtaagca
     3781 aagaattgtg cccacttcaa taatatctac tacatcacca actttcataa catctcctaa
     3841 tgcatgttct aagtcattgt gatctaacgc aatttgcaaa ttcggcctgc tcatcttagt
     3901 tccttccttt acttgttttt ttggtaccac tttgtttcag caaatttttc actgatttct
     3961 ttgactgaca tcacattttt gataccgata actgtaactc cttttttctc tgcctgagta
     4021 aacatattca aaaaattgac tggcgtaaaa actacatcgt attggccagc tgaacttttt
     4081 ccctctgaaa tggcacaatg atggattttg gtaattggta cgtttagttc tttcattgct
     4141 ttttccacac ttctcatcat catcaagctt gttcctgatc catttgcaca cgatactaaa
     4201 attctcatct taatccctcc attatgagtg ttgtctaatc agattttctt ttatactctc
     4261 tgcttttctg catatgtgtc atagtcttct acaatcaaaa aataaccatc aggatttttc
     4321 cgatattgta actgcggaat agccaataaa ccaatgacaa ctacggcaat tccagcataa
     4381 cctaggactt tcatgattac tgtaaacaat ggccaagctg ttgcccagtc gaacatcccg
     4441 atataaccac cgtatgttga catcccaatc catgtagcga ataatgctga accgcctact
     4501 tgtatgattc ctgaaagaaa cgggaacagg caagcggctt tgaatccacc tcggttattg
     4561 gcataaactg ctataacggc attatcaaag aacaacggaa tgaaaccggc tatgacgatc
     4621 gttggtgatt tcaataaaat cagtaaacca atcatcaaaa actgtcccaa agcaccaaac
     4681 aagaacccaa tcgttaccgc atttggcgaa ccaaagccaa aagtagcagc tacgtcaatt
     4741 cctggaacag ctcctggtaa aatcgtgttt gagattcctt ggaaagattg agttagttca
     4801 tcgacgaatg tccgaacacc taattgcaag atcgccagat ataccgcaaa atttaaagaa
     4861 gtcgtcataa tgtagaataa gaaactctgc ccttcttgca tgaattgcgc ttgaatcaaa
     4921 taatctttgc ctagtacaat cagaatgatc ccaaagaaaa atagcatgag taacgaagta
     4981 gcaaccatat tctcattgaa aatcgacaag aatcctggta atttgatatc ttcaattttt
     5041 ttgtcttgct tgattgatct atttttcttt tcatcccgct ttttcatcca ctcagctaat
     5101 tttgcaaata taaagattcc gaacatttgc tgatgtgcca ctgcaaatcc ggcaccttct
     5161 gtcaattcct gcgtgattcc tactgttaag ttagaagcta ctgtccaata acaacctaaa
     5221 atcagtccca taaaaatcaa tgcttgtatc ctacctagat caggaaagca aaacagtaaa
     5281 atccaaaaag cggtagctgc ttgttgaacc tgaacgtttc cggtagtgaa aacggaacgc
     5341 agtttcgtat atttctgaaa acggactaat aagatattta aaacaaatgc aatcagtaat
     5401 aaaatcatca catctccaaa ggtacggcca aatgtctcca ttaatccagc atccacagca
     5461 ttttgtccaa aataaggatc tgtaaccatg gcatccaaat tgaaccgttc ctttagtcca
     5521 accaagattg gccgaaaatt attgaccaaa ccaccagagc caacagtcaa aataaagtaa
     5581 ccgaccgttg cctttaagaa tccagcgatg cattcatgaa gcgggcgttt cagcaaaata
     5641 tagcctaata acacgataaa accaatcagg tatgctggct gcgtcaagat atttgttgca
     5701 aaatacgtcc aaatgcttaa caaaaattcc cccatctttt ttctcctcta tcaattaatt
     5761 atattctgcc atcacaactt ggtaatcatc gatggagttc gtagagatga gacgctcaac
     5821 caatccatct gtcattaata attcggataa tttttggata ttttctagat gttcttctgg
     5881 atcttttgct gcgagtgtaa aaaacaaact agccgttttc tcctcattct ccccttcact
     5941 ttcaaaacgg attggctgtt tcaacttggt aaatgaaata gctgttccaa aaacaccatc
     6001 acttttttct gaagaatgcg gcattgctac ttgaggtgcg atcacaatat aaggaccgta
     6061 tttttctaca caatggatga tctcctccac atacgtttca tcaataattt ccttatcgat
     6121 caatacaaga cagctttcgg cgatagcttc acgccaatcc gtgatttctt tatctgggta
     6181 atgaatcaat tgatggtcaa aaaagtattt cagcaagaaa ctccccttct ttcttataaa
     6241 aacgacggaa acggtgtatc attttcaatc gagaagacat cttcaaatcc tcgataaaaa
     6301 ttaaactcaa gatcatcttt gtttgtcgga tagatgaatt tcccgcctac ttgccagata
     6361 taaggtttaa atccatactt caggcgatcc tttttgaatt tccaaatttc agtgatctct
     6421 tttggatcag ccataaaatt agaccaaata tcgtagtgga caggaatcac tacttttgca
     6481 ttcaatgact ccgccatgcg cagcatatca acagaagtaa ctttgtctgt tatccctcgt
     6541 gggttttcac cataggcccc taaacagaca tcgattttgt gttcattacc atgtttggca
     6601 aataaattgg agtaatgtga atctcctgca tgataaagat tccctcctga tgtttcgaat
     6661 aaatagttta ctgcaatttg atccatctcc tgaggcattt ttccttttaa tacctcttct
     6721 ggatcttcac aagtgaccaa cgctgtccga tcaaacgctt ctaaagctac tacattgatg
     6781 tctttgattt tgactgcatc acctggcttt actgtaatcg ttttttcttc aggaattccc
     6841 catttttgcc acgtgcgaac cacttctttt ggcccaatga atgttgcttc aggacaattt
     6901 tgatgaactg ctgcggctgt atggatatct agatgatcgg aatggatatg tgtaacgatt
     6961 aaagcgtcta cattttttat cgcaaaagga tcgattacga aaggctgagt acgtaaatta
     7021 ggctgcatat tttgaacgcc actcatacgc atcatctgat ggcctttttt catcatgcca
     7081 ttcccatgac tacgttttcc cgtcccacac catagatcac ataaaatatt cgttccttca
     7141 tgacttttca gccaaattcc cgtacagccc agccaccaca tagcaaaagt tccaggatcc
     7201 actacttctg tttcgatttc ttcattcaag tatgtgcccc actcaggaaa tgtttctact
     7261 aaccactttt cttttgttac ttcattgaca gttttactca tttgcttgct ccccccatat
     7321 cgttgttcca acttacaagt aaatattaat gtgtatcagc atccatgaaa acccttttat
     7381 atgaccgttt gttttttata tgattttctt tcagtaatca atgattgttt cagtataata
     7441 aagacagata tgaatgttta aatgaacaac tagtcaaata aatccatgga tcaagatgtc
     7501 cctcaggagg caaaagtcat gaaaaactca cttgtcaata ttgaaaaacg tcaaaaagaa
     7561 attttggaac tgcttcagca gactgaacaa ctatcaactt tcgaattagc tgaatccctt
     7621 gatgtatcta ttagtacgat acgaagagat ttaaatttat tagaagaaaa aaacgagatc
     7681 atacgcaatt acggttattg ttcttataat tacaaaaacc agactgattt tgatcaatct
     7741 ggtcctgaaa ggattaaaca agcgattgcc agagaagcta gtaaatacat taacgattat
     7801 gatacgctgt ttatcaattc tagctcgact gcgttgaaaa cactggattt tcttcaatct
     7861 aaccatttga cagtcattac aaacaacgtg aaaatcaatt actctccgca caaagataat
     7921 tgtagttata ttttaactgg tggagagatg cgctttccaa aagaagcact agtgggcgac
     7981 atcgcattaa atacgatttc ttcagtcaat gcagacattt gtatcattgg ctgtagcgga
     8041 gtcgatgtag tacatggggt cacaacaaag atattaaatg aatcaacgat caacgaaatg
     8101 atggtcaaca agacaatcaa atgtaagatt ttagtcgctg atcatcgaaa aatcggactg
     8161 acatcaaagt tcaagattgc tgatatttca gtctttgatt atttgatcac tgataaattt
     8221 tgttctgaaa aagtattaga ggagatcaga aatacgggga taaaaaccat tcaagtagat
     8281 tcattttaag aaccaggacg taaatatgta aataggatta tcaaaaaaat gaataacaaa
     8341 tttatcgata aatgaaaaac acgctacgct caaattgata aaggaatccc aagatgtatc
     8401 catccaatcg ataccatcat aatctattgc ttcttttata accgttatat gttgcctaaa
     8461 taggaatcaa acaatatcga aaaaaggagg tatgacaaaa gtcacacctc cttttttcgg
     8521 ctctatactt tttgatgttg gtgaacttca ccaacatctt ttttgtataa aaaaatatag
     8581 aaaagacacc ctgaaatcct ttagaattaa tttggctacc aattcatagg aggattcaag
     8641 atgtctcata ctcagcttat caaagatacc ctaaatattc tagacctaaa tatctatttc
     8701 gaggaaaatt gtttaactaa agaaaaatac aaagggcaaa tttgcttgat ttacaaagga
     8761 actcttctgt acaagccaga agagtgttcc cattgtcttt gtgtcgtccc ctctaggatc
     8821 attcgttggg ggacgacaac cgttcggttg ttactgaatg atgtgtctga gtatcgcact
     8881 tatctggagc tgaagaaaca acgatttaaa tgtaagtctt gccaaagaac attcgtagcg
     8941 gatacctctg ttgctgaaaa acactgtttc attagtcaaa aagttcgttg gtctgtcatt
     9001 gctcgcttaa aagagaatac ttccatgacg gaaatcgctc gtcagaaaaa tatttccact
     9061 tcttcggtct atcgtgtcat gaagcgattc taccgcccat tgaatccttt caaacagact
     9121 ttgccaaagg tcttatgctt tgatgaattc aaatcggttc gaagtgttgc cagtgcaatg
     9181 agttttatca tgatggacgg acaaagccat gcattattgg atattgtcga aaatcgacgc
     9241 ttgccttatt tagaacgcta tttttctcgg ttttcattag cgactcgtga agccgttcaa
     9301 ttgattgtta ttgatatgta tgcgccttat gtttcgttgg tgaaaaagct tttcccgaat
     9361 gctcagttga tcatcgatcg tttccacatc gtccaacata ttggcagaac tttcttgaat
     9421 catcgagtga aagaaaccac ggtacgactt aaaggaaatt cccactctca acgagggtta
     9481 gggaaaaaat tgaagcgcta ttggaaactc ctacaaaaag aagaagcaaa gttaaactat
     9541 gaaaaacggg tttggcgtgc cagttttaaa gattatttga ctgaaagtga gattgccgat
     9601 cgactgttag ctgcttgtcc caacttacgc caaggctatc agttatacca agacattctt
     9661 tatgcggtaa agaaaagaga tcagtcacta tttgaggatt gtttaactag agacattagc
     9721 ggtctgccag aaacctatac aaccacttta cgaacgttta aaaagtttct gccacagatc
     9781 caaaatgcgc ttcactacag ctattcaaac ggaccattgg aatgcttaaa caaccacatc
     9841 aaagtattaa aacgcaatgc gtacggcttt cgcaactttt acaatttcaa actacgaatt
     9901 atgattcgtc atggcaaaac atttttaacc aaataaacag aacagaaaga ggttttcttc
     9961 tttctgttct gtcc
//
LOCUS       DAIGUC010000081         9826 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.083, whole genome shotgun sequence.
ACCESSION   DAIGUC010000081 DAIGUC010000000
VERSION     DAIGUC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.083"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..658)
                     /locus_tag="NOB46_002527"
     CDS             complement(<1..658)
                     /locus_tag="NOB46_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI1059430.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     K"
     gene            complement(663..1430)
                     /locus_tag="NOB46_002528"
     CDS             complement(663..1430)
                     /locus_tag="NOB46_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI1059431.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1920..2345
                     /gene="lacA"
                     /locus_tag="NOB46_002529"
     CDS             1920..2345
                     /gene="lacA"
                     /locus_tag="NOB46_002529"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HCI1059432.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2362..2877
                     /gene="lacB"
                     /locus_tag="NOB46_002530"
     CDS             2362..2877
                     /gene="lacB"
                     /locus_tag="NOB46_002530"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HCI1059433.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2888..3820
                     /gene="lacC"
                     /locus_tag="NOB46_002531"
     CDS             2888..3820
                     /gene="lacC"
                     /locus_tag="NOB46_002531"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HCI1059434.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3823..4803
                     /gene="lacD"
                     /locus_tag="NOB46_002532"
     CDS             3823..4803
                     /gene="lacD"
                     /locus_tag="NOB46_002532"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI1059435.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPAIKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4831..5148
                     /locus_tag="NOB46_002533"
     CDS             4831..5148
                     /locus_tag="NOB46_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI1059436.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5148..6854
                     /locus_tag="NOB46_002534"
     CDS             5148..6854
                     /locus_tag="NOB46_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1059437.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7001..8407
                     /gene="lacG"
                     /locus_tag="NOB46_002535"
     CDS             7001..8407
                     /gene="lacG"
                     /locus_tag="NOB46_002535"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI1059438.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8530..8703
                     /locus_tag="NOB46_002536"
     CDS             8530..8703
                     /locus_tag="NOB46_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HCI1059439.1"
                     /translation="MKLPPLLKCGKWYVLTGKEWICHSDLELSAFEWEFLQSLDVEIR
                     ETIHFEVNYLPFQ"
     gene            8724..9623
                     /locus_tag="NOB46_002537"
     CDS             8724..9623
                     /locus_tag="NOB46_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI1059440.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNCPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDKL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3094 a         1666 c         1976 g         3090 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagcagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttt cgtgtattta ggaaaagcaa catcagacca acatctgaaa cgtttgtaaa
      541 tgttatctat ttgttggata tcaatcgttg gaaaacattt ctcaacgcta cgtttaaagg
      601 ggagttgatg gtcataaaga gtgtcatcaa ggtcaaaaac aatattttta taagtcataa
      661 ttctagtccg cttttaaaat agtagtgtac tggctaaatt cctctaagtg ttgagggcta
      721 atctggttat ctgtaatgat ggtatcgagt tgatctagat tatagaagtt aaagaaatcg
      781 tatcgatcga atttagtact gtctactaat aagaattttt ctacagcatt gtttagggca
      841 agttgttgaa tcacaccttc cttgtcacta tatgtagcaa tagaattatg ggtaacagca
      901 tttgcactaa caaaagcttt ggcaaatcta attgctttta aatttgtcga agccattgaa
      961 cctacaaaag ctccagttat ttctctatat tcaccgccaa gaagcaataa atcaatggtt
     1021 tcgctatcat ttagaatcaa gaacacaggg agactatttg taatgacacg aattttataa
     1081 cctttacgac ctttcaattc taatgccagt tgttcaagtg tagttccggg tccaataaaa
     1141 atagtatcgc catctttgat taaagagcag gcttttttag caatgtcaat tttttctttt
     1201 gtatttagac ttttcttctc gatatgtgtc ttttcaagtg gctttttaga ggaaagcaat
     1261 tgtgcaccac catgagtacg tgttaaaagt ccatcagctt ctagagcatc aaggtctcta
     1321 cgggctgtca tatcggaaat atctagttca tctattattt cttttatggt tatggtccca
     1381 tcaatcttta acatatctaa aattttttct aatcgtcgtt ttttgttcat atgaagaccc
     1441 ttctttcata aagtaatttt tttccaaaga taattctctt ttaattgtat cataaaagac
     1501 aatattttca aggtaaaaca aacaatttca aacaaaaaca aatgttagat gatgaaataa
     1561 gaacagtgga ttgacgtata ttagcttagg tcagattttg tataagacga aaataaagta
     1621 ggacctctta atcagtaagt tatagaaagt aaaagacttt tgtaatactt gaatagatat
     1681 ttcacgtcca ttttgtgatg gattaaatga acaaaaatga acaataattt aacggtgtta
     1741 tctatttttt aaaaaaacaa ataaaaaaaa caaaaaataa acaaaaaaag tgttgctttt
     1801 tgtttgaatg cttgatatta tataaacaaa gaaatgatga aaacgttttt tcgaacattt
     1861 tgcaaaatgt tttctacttc tacgtagcat ttctttctaa aatttaggag gtggtcaaaa
     1921 tggctattgt tgttggtgca gatctcaaag gtacgagatt aaaagatgtt gtgaaaaatt
     1981 ttcttgtaga agaaggtttt gaggtaattg atgtgactaa ggacggacaa gattttgttg
     2041 atgttacctt ggcagttgcc tctgaagtaa ataaagatga gcaaaactta ggtattgtaa
     2101 ttgatgctta tggagctggt ccattcatgg tagcaactaa aattaaaggt atggttgcag
     2161 cagaagtttc agatgaacgc tcagcttata tgacacgtgg acataacaat tcacgaatga
     2221 ttacggttgg cgctgaaatc gtcggtgatg agcttgctaa aaacatcgct aaaggtttcg
     2281 tcaatggtaa atatgatggc ggacgtcatc aaatccgagt agatatgctt aacaaaatgt
     2341 gttaagaaaa ggagttaagg aatgagaatc gcaattggat gtgaccacat tgtcacagat
     2401 gaaaaaatgg cagtatcaga attcttgaaa tcaaaaggac atgaggtcct tgatttcggg
     2461 acatatgacc acgcacgtac tcactaccct atctatggta aaaaagtcgg tgaagcagta
     2521 gtaagtggtc aagcagactt gggagtatgt atctgtggta caggtgtcgg cattaacaat
     2581 gcagtcaata aagttccagg tgttcgctca gcgttggttc gtgatatgac atcagctata
     2641 tatgcaaaag aagagttaaa tgcgaatgtt atcggtttcg gtggaaagat tactggtggt
     2701 cttcttatga atgacatcat tgaagctttc attgaagctg agtacaaacc aacagaagaa
     2761 aataaaaaat tgattgcaaa aatcgaacac gttgaaacac ataatgcaca tcaagcagat
     2821 gaagatttct ttacagaatt ccttgaaaga tgggaccgtg gtgactacca cgattaaggt
     2881 ataacaaatg attctgacag tcacactaaa tccttcagta gacatctctt atcctctaga
     2941 aacattgaaa attgatacag tgaatagggt gaaagatgtt agtaagacag ctggtggaaa
     3001 aggcttaaat gttactagag tcttgtatga atctggtgat aaagttactg ctacaggttt
     3061 cttaggtggt aaaattggtg aatttattga aagcgaatta gaacaatctc ctgttagtcc
     3121 agctttttat aaaatctcag gaaacactag aaactgtatt gctatcttac acgagggtaa
     3181 ccaaacagaa attttggaac aaggaccaac aatttctcat gaagaagcag aaggctttct
     3241 tgaccactat agcaatctta ttaaacaatc agaagttgtg acaatttcag gaagtttacc
     3301 ttcaggactt cccaacgatt attatgaaaa acttatccaa cttgcttcgg atgaaggagt
     3361 agcagtcgtt ttggattgtt caggtgcacc tcttgaaaca gttctaaaat cgtcggctaa
     3421 acctactgcc atcaaaccta ataatgagga actttcacag ttgcttggaa aagaagtaac
     3481 aaaagatatt gaagaactca aagacgttct taaagagtca ctttttagtg gtatcgaatg
     3541 gatagtggtc tcattaggtc gaaacggtgc ctttgcaaaa catggtgatg ttttctataa
     3601 ggtagatatt cctgatatcc cagttgttaa tccagtcgga tcaggggact caacggtagc
     3661 tggtattgca tcagctttaa atagtaaaaa aagtgacgct gacttattaa aacatgcgat
     3721 gacattgggt atgttaaatg ctcaagaaac aatgacaggg catgtgaata tgactaatta
     3781 cgaaacacta aactcacaaa ttggagtaaa agaggtataa aaatggtact tacagaacag
     3841 aaacgcaaat ctttggaaaa aatttcagat aaaaacggtg ttatctcagc tttggcattt
     3901 gaccaacgtg gtgctttgaa acgtttgatg gcacagtatc aagatacaga accaactgta
     3961 gctcaaatgg aagaactaaa ggttttggtt gctgatgaac ttacaaaata cgcttcttca
     4021 atgttgcttg accctgaata tggacttcca gcaataaaag cattggataa agaagcaggt
     4081 cttcttcttg cctatgaaaa aacaggttat gatacatcaa gtacaaaacg tttgcctgac
     4141 tgcttggatg tttggtctgc aaaacgtatc aaagagcaag gcgctgatgc cgttaagttc
     4201 ttgctttact atgatgtaga cagctcagat gaacttaacc aacaaaaaca agcttatatt
     4261 gaacgtgttg gttctgaatg tgtcgctgaa gatattcctt tcttcttgga aatccttgct
     4321 tatgatgaag aaatctcaga tgcaggttct gttgaatatg caaaagtgaa acctcgcaaa
     4381 gtcattgaag cgatgaaagt tttctctgat ccacgcttta acattgatgt tcttaaagta
     4441 gaagtaccag ttaacgttaa atatgtcgaa ggttttgctg atggtgaagt ggtttacagt
     4501 aaagctgaag ctgctgactt ctttaaagca caagaagaag cgactaacct tccatacatc
     4561 tacctaagtg caggtgtatc tgctaaattg ttccaagaaa cattgcaatt tgctcacgac
     4621 tcaggtgcca agtttaatgg tgtgctttgt ggacgtgcta cttgggcagg atctgtagaa
     4681 ccttacatca aagaaggtga aaaagcagca cgtgaatggt tgcgtactac tggattcgaa
     4741 aatattgatg aacttaacaa agttcttgtt aaaacagcta gtccatggac tgataaagta
     4801 tagtaaaaac ataaaacgga ggatattgtt atgaacagag aagagatgac tctcttaggg
     4861 tttgaaattg ttgcttatgc tggagatgct cgctctaaac ttttagaagc gcttaaagcg
     4921 gctgaaaatg gtgatttcgc taaggcagat agtcttgtag tagaagcagg aagctgtatt
     4981 gcagaggctc acaattctca gacagctatg ttggctcgag aagcttctgg ggaggaactt
     5041 ccatacagcg ttaccatgat gcatggtcag gaccacttaa tgactactgt cttattaaaa
     5101 gatgtgattc atcacctcat cgaactttat aaaagaggag caaaataatg cataaactca
     5161 ttgaacttat tgagaaaggg aaaccgttct ttgagaaaat ctctcgaaac atctatcttc
     5221 gtgctattcg tgatggattt atcgctggta tgccagtcat ccttttctca tctatcttta
     5281 tccttattgc ctatgtccca aatgcttggg gattccactg gtcaaaagac attgagacct
     5341 tcttgatgac tccttatagc tattcgatgg gtatcctagc attctttgtt ggtggtacta
     5401 ccgctaaagc tttgacggac tcaatgaacc gtgacctacc tgcgaccaat cagattaact
     5461 tcttatctac gatgctagcg tctatggtag ggttcctttt gatggcagct gagcctgcaa
     5521 aagaaggagg cttcttgaca gccttcacgg gaacaaaagg tcttttgaca gcatttattg
     5581 cagcctttgt gacagttaat gtttacaagg tctgtgtgaa aaataatgtt actattcgta
     5641 tgcctgaaga ggttccacca aatatctctc aagtatttaa agacttgatt ccattcactg
     5701 tagcggttgt tctcctttat ggatttgaac tcattgttaa gggaactctt ggtgtaaccg
     5761 ttgcagaatc aatcggtacc cttcttgctc ctctcttctc agctgcagat ggttaccttg
     5821 gaattacact gatctttggt gcttatgcct tcttctggtt tgttggtatc cacggtcctt
     5881 caattgtcga accagcaatc gctgctatca cttatgccaa tatcgatgcc aacttgcatc
     5941 ttatccaagc tggacaacat gcagataaag ttatcacttc tggtactcaa atgtttattg
     6001 ttaccatggg tggaacagga gctacattga ttgttccatt cttgttcatg tggatttgta
     6061 aatcagaacg taaccgtgcc atcggacgtg cctcagttgt tccaacattc tttggggtta
     6121 atgagccaat cttatttggt gcaccaatcg tattgaatcc gattttcttt gtaccgttca
     6181 ttttcgctcc gattgtcaac gtttggatct ttaaattctt tgttgacaca ttgaacatga
     6241 actcattctc tgccaacctt ccatgggtta ctcctggtcc gttgggaatt gtactcggta
     6301 ctaacttcca agttctatca tttatcttag ccggactctt ggtagttgtt gatactatca
     6361 tttattaccc atttgttaag gtatacgatg aacaaattct tgaagaagaa cgttctggta
     6421 aaacaaacga tgctcttaaa gaaaaagtag ctgcaaactt caatactgct aaagcagatg
     6481 ccgttcttgg aaaagcaggc gttgctaaag aagatgtagc agcaaacaat aatatcacaa
     6541 aagaaactaa tgtccttgtt ctttgtgcag gtggaggtac aagtggcttg cttgccaatg
     6601 ccttgaacaa agcagcagca gaatacaatg ttccagtcaa agcggcagcg ggtagttatg
     6661 gtgctcaccg tgaaatgttg ccagagtttg acttggttat cttggctcca caggtcgctt
     6721 caaacttcga tgatatgaag gctgaaacag ataaattggg cattaaactt gcaaaaactg
     6781 aaggagctca atatatcaaa ttgacacgtg atggacaagg tgctcttgca tttgttcaac
     6841 aacagtttga ttaataaatt tgtaaaagtt atttgagacg agattattct ttcagttcct
     6901 tataatattg ttaaccatat cattgcattt catttcattt ccttggtttc cggaactcag
     6961 aatatcgtct caaatgcttt ttttgaaagg atttatagtt atgactaaaa cactccctaa
     7021 agattttatt tttggtggtg ctacagctgc ttatcaagca gaaggtgcga ctcacacgga
     7081 tggtaaaggc ccagttgcat gggataagta tcttgaagac aattattggt acacagcaga
     7141 gcctgcaagt gatttttacc ataaatatcc tgttgattta gaattagctg aaaaatatgg
     7201 cgttaatggt attcgtattt caattgcctg gtctcgtatt ttcccaactg gctatggcga
     7261 agtaaatgaa aaaggtgttg aattctacca taatcttttt gccgagtgcc acaaacgtca
     7321 tgttgagcca ttcgtgactt tgcaccactt tgacacacca gaagttcttc actcagatgg
     7381 agatttctta aaccgcgaaa atatagaaca ctttgtagat tatgccgctt tctgttttga
     7441 agagttccca gaagtaaact actggacaac tttcaatgaa attggcccaa ttggagatgg
     7501 tcaatacttg gttggtaaat tccctccagg cattcaatat gatcttgcca aagtcttcca
     7561 atcacaccac aatatgatgg tttctcatgc acgtgctgtg aaattgtata aagataaagg
     7621 ttataaaggc gaaattggtg tagtacatgc gttgccaacc aaataccctt atgatccaga
     7681 aaatccagca gatgttcgtg ccgctgagtt agaagatatc atccataaca aatttatctt
     7741 ggatgcaacc taccttggac actattcaga taaaacgatg gaaggggtca accacatcct
     7801 agctgaaaat ggtggagaac ttgatcttcg tgatgaagac ttccaagcac ttgaagcagc
     7861 taaagatttg aacgatttcc ttggtatcaa ctactacatg agtgattgga tgcaagcctt
     7921 tgatggtgag actgaaatca ttcacaatgg taagggtgaa aaaggaagtt ctaagtacca
     7981 gattaaaggt gttggtcgcc gaatcgcacc agattatgtg cctagaacgg attgggactg
     8041 gattatttat cctgaaggct tgtatgacca aatcatgcga gtgaaaaatg attatccaaa
     8101 ctacaagaag atttacatca ctgaaaacgg tcttggatac aaagatgagt ttgtagataa
     8161 taccgtttat gatgatggtc gtattgatta cgtgaagaaa cacttggaag ttttatcaga
     8221 cgcaattgcg gatggtgcaa atgttaaagg ttacttcatc tggtcactta tggatgtctt
     8281 ctcatggtca aacggatacg aaaaacgtta tggactattc tatgtagact ttgacacgca
     8341 agaacgctat cctaagaaat cagctcattg gtataagaaa gtagcagaaa ctcaagtgat
     8401 agagtaatat tacttgaaaa tgtaaaaaat tgttatccga tactttagaa aaagtacaac
     8461 acttatttag accaggcttt gaaaaggtat atattgttag tttcgaagat tgtcctatga
     8521 ttcctgagct tgaagctacc cccgttgcta aaatgtggta aatggtatgt tttaactgga
     8581 aaagagtgga tttgccattc tgatttagag ttatcagcat ttgaatggga atttttacaa
     8641 tcactcgatg tagaaatacg tgagactatt cacttcgagg taaattattt gcctttccaa
     8701 taataaaaag aaaggaatta gttgtgacta tcgaattaaa aaacgagtat cttactgttc
     8761 agtttaaaac acttggtggt caactgactt cgattaaaga caaggatggg atagagtatc
     8821 tctggcaagc tgatccaaat tattggaatg gacaggcgcc tattctattt cctatctgtg
     8881 gtagtttacg aaatgattgg gctatttata gacctcaaga aagacctttt tttacaggtc
     8941 ttattcgtag acatggtttt gttcgaaaag aagaatttat tctggaagaa gtcaatgata
     9001 atagcgtgac ctttagtatt aaaccaaatg ctgagatgct tgataattac ctatatcagt
     9061 ttgaactgag agttgtttat accttgaatg gtaaatcaat tagaaccgaa tttcaggtaa
     9121 cgaacttgga aatggaaaaa acaatgcctt actttattgg agcccatcca gcattcaatt
     9181 gtcctttagt agaaggtgaa aactatgagg attattatat tgaatttagt gaggttgagt
     9241 cttgctcgat accaaagagt tttcctgaga caggattatt agatttgcaa gatcggacac
     9301 cttttttgga aaatcaaaag attctcgatt tggactactc acttttttcc catgatgcca
     9361 ttacacttga caagctcaag tctcgtagcg taacgcttcg gtcaaggaag tctggtaaag
     9421 gtcttcgagt agattttgat gattttccga acttgattct gtggtctaca actaataaaa
     9481 gtccattcat tgctttggaa ccttggagtg gtctctccac ttcacttgaa gaaggtaatt
     9541 tcttagaaga taaaagacag gtaacgaaaa tttcacctca agaaacttct agaaaaatct
     9601 atgatattac tatccttaat taaaatttgt tattatttga gtcttcaata agaattgaat
     9661 actcttacct tgtgatgata gattggtctt ctccgtgcca gtcttacatc gcaaggtttt
     9721 taagtttttt gtgggtctat gtcaactgta gtgggtgacg aaaagctaac atctaaagac
     9781 agtctggtag taaaaaaata agattattta ctacttcttg atttaa
//
LOCUS       DAIGUC010000082         9647 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.084, whole genome shotgun sequence.
ACCESSION   DAIGUC010000082 DAIGUC010000000
VERSION     DAIGUC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.084"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(59..601)
                     /locus_tag="NOB46_002538"
     CDS             complement(59..601)
                     /locus_tag="NOB46_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HCI1059441.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            736..1125
                     /locus_tag="NOB46_002539"
     CDS             736..1125
                     /locus_tag="NOB46_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059442.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1129..1893
                     /locus_tag="NOB46_002540"
     CDS             1129..1893
                     /locus_tag="NOB46_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI1059443.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2022..2969
                     /locus_tag="NOB46_002541"
     CDS             2022..2969
                     /locus_tag="NOB46_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1059444.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3099..3839
                     /locus_tag="NOB46_002542"
     CDS             3099..3839
                     /locus_tag="NOB46_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059445.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4130..4798)
                     /locus_tag="NOB46_002543"
     CDS             complement(4130..4798)
                     /locus_tag="NOB46_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI1059446.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4932..5219
                     /locus_tag="NOB46_002544"
     CDS             4932..5219
                     /locus_tag="NOB46_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059447.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5635..7173
                     /locus_tag="NOB46_002545"
     CDS             5635..7173
                     /locus_tag="NOB46_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HCI1059448.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7170..8135
                     /locus_tag="NOB46_002546"
     CDS             7170..8135
                     /locus_tag="NOB46_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059449.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8122..9444
                     /locus_tag="NOB46_002547"
     CDS             8122..9444
                     /locus_tag="NOB46_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI1059450.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9507..9611
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
BASE COUNT         3226 a         1644 c         1980 g         2797 t
ORIGIN      
        1 aaaactgtct aacatttaaa atttaattta gatattagac agtttttaag tttgtgagtt
       61 attttccttg tcgttttctc acttttttag tccagaaacc acctgaaata tattttggct
      121 cataagaaat gataaaagca cgctcttcga tttctttgat caggcgatac agttcacgtt
      181 cgctttttct aggagaaagt atttcgagaa ctagccgctc accttccagc cccattgcag
      241 aagtctgtgt cacaccataa ccgtgttctc tcagtatacc cggcaaactt ttatcttctg
      301 cgctatttgc tggcaaaatc gttgtgacca tgatgtatcc taatgccaat ttgtcttcaa
      361 tcaaaattcc gacactgata cctactgcgt aacctaacgc atagacaaat aaattcagtg
      421 gattatctaa acgatctaaa acaagggata agccgacgat ataaatcgtg atctcgacca
      481 tactgacaag tggagcaatc agtcgatagc ctttcattgt caacatgaaa cgtaacgtgt
      541 tcagagtgat ataagcaaaa ttaatgagga agatcatccc caacattttt ggatcaatca
      601 tttgtaaaac tcctttcatt tatataacaa caatatcaaa aaaaatcgta agtgaagaaa
      661 aattgaaact ttatacatac aaaaaaatga taaaatgatt ataatagaat tataaagata
      721 ggttaggtga ttaaaatgaa aacggtcaat cgtgtgtttt gtgccagcca cgtgctaagt
      781 ctccttctca gtatatactt aggtgtctat tcgattcaac agccaattga ggtagagaac
      841 attgtttttc agatgtcgct gacagatggt ttaattttaa gcgttttttt ctttttgata
      901 ctgtttattg gtaatatttt cggtagcgtt gccagttttt tgaatttttc tatttatcca
      961 ctcctttcgc tagcattagg agtggtggga ctttgttctc tgtgcttatt tcccgagcca
     1021 ttcagtcctg catttatatt atttggtaca ctgaacctgt tccagacaac tgttggagca
     1081 tggttgctat ggcgatcagg aaatttaatg aaaataggtg agtaacaatt gaatccaatt
     1141 atattgaaac gttctgtcca tcatattcca gtgttagaag ttgttctgaa agaattaaga
     1201 gaggaacgta ttcccgttgt catctattat cacggatggc agacaagtaa ggagttagtt
     1261 ttgacgcaag gaagaaaaat tgcgcagcag ggcattcgtg tgatcctgcc agatgcgatg
     1321 aatcatgggg agcgcaaaca gccggtttct tctattccat cctatacatt ttgggatagt
     1381 atctacggaa atctgtttga atttgacaca cttatcaagc atttagaaaa aagaggtctt
     1441 ctacatgatc agcttgcagt tggcggggtt tcgatggggg gaatgacaac atgcgccttg
     1501 ttggctaaac atcctcatat agtagcgggc gtgtgtttga tgggttcccc tgcacctttg
     1561 gaatatggaa aagaaatcgt aaggcgcgca tcggaatata attatgtcgt accaaaagac
     1621 tattttgatt tgatttcatg ggttaagagc tatgatttgt cattgcagcc ggaaaagtta
     1681 gctggacgtc ctctgttctt ttggcatgga caagctgacg aaaaaatccc ttatatacaa
     1741 acggaacgat ttgtagaaaa aaatcggcat aagtcttacg gaaaagaaat tgtttttcgt
     1801 tcctcaaaaa cacagcgaca tatggtacaa ataccactaa tggaagaagc ttccactttt
     1861 ttagcaaaaa atttgataaa aaagtataaa taattgaaac ggaaaatcac tcatgacgat
     1921 agaggatttt ccgtttttta ttttgggcta taataaactc tgttaggaaa atttggtata
     1981 attgatagta agaatgacaa catgttagaa aggaagagag catgcccact ttagcagatg
     2041 ttgcaaaacg tgccaatgtt tcaaaaatga cggtctctcg agtcatcaat catccggaac
     2101 aggtgactga cgaattgaaa gagttagttt tctcagcaat ggctgaactg gattaccgtc
     2161 caaatattgc tgcaaaagca cttgtcacga atcggtcgca gatcatcaaa ttatttatac
     2221 tggaagaaat cgacacaact gagccctatt acatgaattt gctgatggga atcgctaaac
     2281 ggatcggtaa agcgcattat tctctccaat tagttacaaa tgatgccttc gacgtcggtt
     2341 cttgtgatgg atacatcatc acaggtgtca gaaaaaaaga cttcgattgg atcgaccgtt
     2401 tggaaaaacc agttgtcttg tttggggaaa attctgaagg atatgattat gtagacagcg
     2461 ataatgaata tggtacagca aaagcaacgc aatatgcctt agaaagagat tatcaaacga
     2521 ttatttatat cggtatcgaa gtggacgagc cttttgaaat ttcaagggaa actggttatt
     2581 tatctgtgat gaaggaagtt gatcttccta gtaaaatctt gcggtttcca aatcattcga
     2641 cagaagtaga aagatatatg acagaaaact gggcagattt tacagataaa acttgttttg
     2701 tatgtagttc agatcggcta gcactaggag cagtaagagg gattataaat gctggaggac
     2761 acttgcccga agaatttggt gtgattggat ttgatggggt atttttagac caaatcagtt
     2821 cacctaaatt gacaacgatc aagcaagata ttatacgtat gggtgaagta tgtggagaaa
     2881 tgttgttaaa aaaaatagaa gaaaaagggg cgagtcaagg ttatcgtcgt ttttttcctg
     2941 aactagttat cagagagaca acgaattaag tcttattact atatatatat ttatgaaatt
     3001 catcgctatt ttcttaaaat aatcagcgca ttgctactga aaacaatgaa tctgtgctat
     3061 tattgagaaa agttccattt ttgagaagga tggtttgaat gaaagaaatc agacgaaaac
     3121 atttccgttt tcctgcgtac gatgatgagt taggcgtaaa attaaccaac gacaagaagc
     3181 gagtattatt tgacggacaa gaagatcttt tgactgaaca gaatcagtcc ccgtttgaac
     3241 agatgaaaga atttcatttc acgaacacga acaccgagaa aatccgtcgc aagcgtcgtg
     3301 caacaaatgg attgaagtca gctccgcgta aggaaaattt ggaaaagcat aaaggaaaat
     3361 taccggatta taccggccat taccaatcag aaatcacatc gacaggacga aaaaaacttt
     3421 ttggtgattc ctctcgttct gtcagacaaa gtgaaacaag gacagagtcc aagcatacta
     3481 cacgaaacgc atctgttgac acgaaggtgc gggagcgttc ttattttgtt cctaaatatg
     3541 tacccgcatc gattatccca gaccctagag aaagcaaaat ttctgaggat catttaatcg
     3601 aatcgatgaa aaaaacggat gactcttatc tgttgttcga tacagaaccg acgccgtatc
     3661 aagaaaaaag aaatggtgag ccgtctgtac gaacattcaa tcgaacaaaa acgttagagg
     3721 aaacaaagca gtcagaagaa aaaaaatcga aaaaaagcca tggtatctta gaacgctcat
     3781 tacaaggatt gatcgatgat caaggaaact ctttgggaga aaatagctat tttaaataag
     3841 tgatatacaa atttatattc ggctacagtt ggaaaggaaa cgctgcggcg tttccttatt
     3901 ttatactcta tccgaaagtt tatatcgtat cctcaaattt ttttgagttt aagcgaattt
     3961 tttctcccaa taagtaagaa aataatggca aaataaaaaa acaaactatt ttcgcagatc
     4021 gtttgcaaaa atagtttatt tttttataaa gaagatttta ctgaataata tcattttagt
     4081 ttacataatg atatttctgt aaattaaata aagtagtgaa aaataagaat cagtgctcta
     4141 actgttcaag aggatcaagt ggttcaaatg tttctgtagt ctgttttgct tccaattggg
     4201 gcaaaacaga tccaatttcc agatacttca ctttattcaa tgtataagat agaatagaac
     4261 agctaagtaa tgtatacaga aaatgtgtga gatccaaata aagcaaggag acaactaaaa
     4321 taccaaaagt aatcaagaaa agacttttgc caatcttaat atgaaaatat ttttcaatgg
     4381 cttgataaat gatatctgtt ccgcctgtgc ttccgccgaa tcgaaagacg agaccgcaac
     4441 caatgccaga aagaatacct gtcatcaaac tattgatcag tagactatct acagcaaaat
     4501 gtatatgaag gctctcccat aaatgtaaaa agaaaactag cgcaaatgtt ccgacgatcg
     4561 tccggagaaa agcgtgtttt ccaaaaagaa acaatgagat aagcaataaa ggtaaattaa
     4621 aaagcagtga agtgacagaa ggagcgaatc caaaaagatt atgcaaaagc aaagcaatac
     4681 cagtaacccc accatctgcc agcttagatg gaatattgat tcctgtcaca gctaatccgt
     4741 agattcctgc gcctaaaatg attccgcaca attctgtaaa taaatttaat tttttcattt
     4801 ctagcctctt ttcttttgaa aattttcagc aacttcttta ttatactgac ttatactctt
     4861 acttcaagag gaaaatgaaa aaaaattatt tttggctgtt tctttttatt tatcaaataa
     4921 ggagtggaaa aatgcgagca gcagacttat tgacaattct tacaaaatca cccaaaaaaa
     4981 cagagtatca aggagttttt ttggctcaag aacaaaaact ggtgcctgtg acaatggtcc
     5041 agataaataa agcaaatcaa tttatctttt tatttgaaca cggcaaagca ccacttgcta
     5101 tgaaagacat ctttcttttt ttgatgaaga accgtgagaa agctgtttat tatcagtcaa
     5161 aagaagaact cattcctctt tatggagtga aagagataga aaataaagtg gtgatataag
     5221 taaaaataag aaaacaagac gtttatgatg tcaaaacaac cattttttac atttttggca
     5281 aaaaagtgtc atgatacagt ataatattcg ttgaacaggc caataaaggt gttctccccc
     5341 acgagatttc tactttattg gctgtttctt tttattaaaa taaaagttgt gtgtgtaaaa
     5401 aagatatagc tgattccaag tgacaatttc gtatagattt ttatggtatt cgtagtgaaa
     5461 aaacgagaac caaaaagttg atccgacttt gttgcttgga ttcttttttt gtcagcatat
     5521 ttagaggtat ttttttcttt tttttgttcg tgctgtaagg ttaaggcaag acaagttagt
     5581 tgggaaaaag gaaagaaatg tttatactta aagaataaca gaaaggaagg tcgcatgaat
     5641 aattttatac aaacattaag tgaaagaaaa ggcgagttgc tggaagctgc atttcaacat
     5701 ctgtccattt ctctcatttc tttgctgatt gcagcactga ttgctattcc tttagcgatt
     5761 tgggcagcca atcataaaaa aatggcagaa gtcttattgc agatcacggg tgtgctccaa
     5821 acgattcctt cacttgcctt attaggttta cttatcccat ttgtagggat cggaactgtt
     5881 ccagcattga ttgcacttgt tatttacgct ttgcttccga ttttccaaaa cacgtatatt
     5941 ggtctagctg aaattgaccc gtctattgaa gaagcagcgg tagcatttgg tatgtccaga
     6001 atgagacgct tgctgaaagt agagcttccc atcgcattac ctgtcattat ctcaggtatc
     6061 cgaactgcct tagttttaat catcggtacg gctactttgg cagcattgat cggagcaggt
     6121 ggattaggga catttatttt gttaggtatt gaccgaaata cacctgtttt gacattgatt
     6181 ggtgcgatca gttctgcctt gcttgcaatt atattcagcg gactgattcg ctggttgcag
     6241 cataagaaac ctcgatattc catcattact ttagcagcag tggtgtgttt atttggcggc
     6301 gtttctttat atcagtctgc cttgtttaaa aatgaaacca tcacgattgc tggaaaatta
     6361 ggagcggaac ctgaaatcct gatccaaatg tataaagaat tgattgaaga caacacaaaa
     6421 acagaagttg aattaaaacc gaattttggc aagacgagtt ttttgttcaa tgcactggat
     6481 caaggtcaaa tcgatatcta tcctgagttc acaggtactg tcctagaaag cttggtgaag
     6541 gtacctgaag caatgaaaag tgctgatttg acaaaagaaa aaacatatga cgaagcagaa
     6601 gaattattga ataagcaatt cgatatgaca ttattaaaac caatggctta ccaaaatacg
     6661 tatgccttgg cagtcaagag atcttttgcg aacgaacatc aacttaaaaa gatttccgat
     6721 ttggcagcta tctctgatca gatcaaagcg ggattcacac tggaatttat tgatcgttca
     6781 gatggatata aaggaatcca agaagcatat ggcttgaatt tttcaagtgt acaaagcatg
     6841 gagccaagtt tgcgttacca agcaatcaat aatggagatg tcaatattgt ggatgcctat
     6901 tccacagata gccagctcaa ggagtacgat ctagtgactc tagaagatga tcgagggtta
     6961 ttcccagctt atcaaggcgc accgctgatg aaaaaagatt ttgctaaaga acatcctgaa
     7021 atcgttaaag cactgaataa attaagcgga aaaataacag aggatcaaat gattgatatg
     7081 aattaccaag tcaatgtcga aaagaaaaag ccgacagaag tagcacgaat cttcctgaaa
     7141 aatgaaggat tagtaaagga ggaagatcag tgactaaatt aatcgagttc aaacatgtgc
     7201 aaaaaaagta tgatggaaag tatgtcatcg atgacctaaa tctggcaatc aaaaaaggag
     7261 aaatctttgt tttggttggt ccttccggta gtggaaaaac aactactttg aaaatgatca
     7321 atggattatc taaaccatca gcaggagaca tctacttcaa aggaaaatcg ttaaatgaat
     7381 ataatctgca gaaaatgcgg tggaatatgg gatatgtgct gcagcaaatc gctttgttcc
     7441 cgaccatgac agtcaagcaa aatattgaag tcatccctga aatgttaggt tgggaaaagc
     7501 agaaaagagc agaccgtgta gatgaacttc ttcaaaaagt tggcttatct cctgatattt
     7561 atcgagatcg tatgcctaga gagttgtctg gaggagaaca gcaacggatc gggatcatcc
     7621 gagctattgc tgcaagccca gatgtgattt tgatggacga gccatttagc gcattagatc
     7681 cgatttcaag aaactcatta caagaattgg ttttgtcctt acacgaagaa ttgggcacga
     7741 ccatcgtttt cgttacgcac aatatggaag aagcaatcaa gctaggtgat cgtattgcat
     7801 ttatgaagga tggagaaatt atccaatgtg acacaccaga gcagttattg atgaatccta
     7861 aaaacgacta cgttcggcat ttctttgatg aaccgaaaca gacgaaagag tggcgagtag
     7921 aagatttagt cgtcaatgga tatttcttaa atgaaatacc agaaaatgct cgtcaacaag
     7981 tttgctttga tacgcctatg aaagaagtat attcgcttct ttcggtgtat ccaagcattg
     8041 tgatagtaga aaagcaaaga agtattgggt cgctgacaag taaagaaatc tttgcttttt
     8101 taagtcgaga ggaggaagga aatgaaaaca tatgatgcaa tcatcatcgg ttcaggtgtg
     8161 agcggcttaa gtgctgctta tggattgaaa gaagcaggta aaacagtact agtggtcgaa
     8221 gaagatctat ggggcgggac ttgtcctaac cgtggatgtg atcctaaaaa agtcttgtta
     8281 agtgcagtag aggcacgtaa tcgggtaaaa caattgagtg gaaaaggttt taacgagatc
     8341 ccaactgcca actgggaaga acttcaaaaa ttcaaacgaa catttacgga tccagtccca
     8401 gaaagccgaa aaaaacaatt agcagaagct gaaatcgatc atctttcagg aaccgctcgt
     8461 tttttggatg attcatctat tgaagtcaac gaagaagtct tccatgcgga ttacttagtt
     8521 ttggcaaccg ggcaaagacc tacgatctta ccagtggagg gaaaggaata cttgaaaact
     8581 agtgcagact ttttatcatt gcctgtactg cctaaagaaa tcatttttat cggtggtggt
     8641 tatattgctt ttgagctagc tacgattgcc aatgctgcag ggagcaaagt aaccattgtc
     8701 catcataatc aacggccatt aaaagaattt gaggcgtctt tggtagagga agccgtccat
     8761 caaatggaag catctggcat tcagtttgct tttggtgttg aaacccaaaa gatcatttca
     8821 gaaggtactc gctatcgttt agtcggaaaa gagacggaat tagtagcaga tatgattttt
     8881 tgtgcgactg ggagacagcc gaatacagaa tctttagcac ttgagcaagc gaatatcgtc
     8941 tttgataaac acggaattgc agtcaatgat tatctgcaaa cgagcaatcc aaaaattttt
     9001 gcgtgtggag atattgtttc aaggaaaacc ccaaaattga caccagtcgc cacttttgaa
     9061 ggaaattatg tagctaagcg gataacggat gcaacaagcg aacctatcaa atatccgatt
     9121 atacctacga tcgtctacgc cagtcctaaa cttgctgaag taggagttac aaaaagtcac
     9181 gcctcttcgt cagatcaagt ggtagagatg gatcttacca gttggttcac ctatcatcgt
     9241 gtcaatgaac cagttgctaa ggctgaattg acctttgacc agcaaaatta tttgattggt
     9301 gctgcagtga ttagcgagca agcagacgaa ttgatcgatg atttgacact cgtcatcaat
     9361 caaaaattga ctaaaaaaga gttggatagc tatatcatgg ggtatccgac attggcaagt
     9421 gatctctcct atttattgaa ataatcagca tgataactaa agcgcttgtt gctttttcct
     9481 tcttgtgcta cactttaaaa aatgaatacc tgtttctggg gatgtcgtag acgacatgag
     9541 agtaagttgt gaacttagac ccattgaacc tgtcagttaa tactggtgaa gggagaaaca
     9601 tagcagacgc ttgaagcggg ttactatgtc gtgcccattt caagcgt
//
LOCUS       DAIGUC010000083         8254 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.085, whole genome shotgun sequence.
ACCESSION   DAIGUC010000083 DAIGUC010000000
VERSION     DAIGUC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.085"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..191)
                     /locus_tag="NOB46_002548"
     CDS             complement(<1..191)
                     /locus_tag="NOB46_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI1059451.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWK"
     gene            519..746
                     /locus_tag="NOB46_002549"
                     /pseudo
     CDS             519..746
                     /locus_tag="NOB46_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            872..1843
                     /locus_tag="NOB46_002550"
     CDS             872..1843
                     /locus_tag="NOB46_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1059452.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            1984..3297
                     /locus_tag="NOB46_002551"
     CDS             1984..3297
                     /locus_tag="NOB46_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI1059453.1"
                     /translation="MKRRMLAIAAILALTAGGLAGCGSKEKSSGSSDSGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFVWSNGGDVVNADGTKAEDYFNDKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMLLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIISLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQISGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            3340..4206
                     /locus_tag="NOB46_002552"
     CDS             3340..4206
                     /locus_tag="NOB46_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI1059454.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQLGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            4203..5051
                     /locus_tag="NOB46_002553"
     CDS             4203..5051
                     /locus_tag="NOB46_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI1059455.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            5065..6537
                     /locus_tag="NOB46_002554"
     CDS             5065..6537
                     /locus_tag="NOB46_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HCI1059456.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWINDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMTAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKGLVYDQHYLRLEINLKQATKLELHYAKGPHHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            6554..7426
                     /locus_tag="NOB46_002555"
     CDS             6554..7426
                     /locus_tag="NOB46_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI1059457.1"
                     /translation="MIYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(7660..8045)
                     /locus_tag="NOB46_002556"
                     /pseudo
     CDS             complement(7660..8045)
                     /locus_tag="NOB46_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2528 a         1457 c         1754 g         2515 t
ORIGIN      
        1 tttttccaaa tttgatagag tagtttgcca tattcttgca cccaacgata aatcgtcgta
       61 tgagaaacgt taatgccacg atcatataag atttcttgaa cttcacgata gctaaggtta
      121 taacgaagat agtatcccac ggctacaata atcacatcct gctgaaattg ctttccttta
      181 aaatgattca tcgtcattcc tcctgctatc tttttctatt attctacctt atttgatagt
      241 agatttaaaa ctttgcaaca gaaccacatt aattttgttg gcaaatatag tttccgctat
      301 gaaaaagaat tatcgaatgg aatactacgt ccgttaaata tagagaatta ttgagaatgt
      361 tcgtcttttg gttcctaccg tgcattttcg cacggatgtt ccagatacta tttttgaatg
      421 tataaaattg aaaacacaag aatcctatta aatcaacgat tcttgtgttt ttaatttttc
      481 actaccgtgc attttcgttt ctatgttcca tgtaccccaa tcttgaaaaa ttaattaaag
      541 acttatataa agccattgac gacttagtcg tggtgctacc ggagtatcaa tgtttaacca
      601 gtatcccagg tattggtcct gtttaggctg ctggaatact cgctgaaatt ggtccaattg
      661 aacgtttttc tgatgaaata aaattgacaa agtatgccgg cctatattgg cgacagagtc
      721 aatccggtaa atctgaatac gaaaattttt ttacgaaaag cttcacgtct aatatctatt
      781 ttaaaataaa aatattcctg ctaatttgga atcgtttcct tcttttggta taataatacc
      841 tgaaattctt ttgagaggag ttgttcgtga agtgaaaact actatgaagg atgttgctgc
      901 gttagcagga gttggtgtgg gtacggtatc tagagtaata aatggagtaa aggtgaaaga
      961 ggttaccaaa gaaaaagtaa tggctgcaat tagtgagctt aattatgagc ctgatgaata
     1021 tgccagaggt atgaaaacga atagcagcaa tacaatagct cttattttac ctacgatttg
     1081 gcatcccttc ttttccgagt ttgcctacta tgtagaggaa gctctcagcc aaaaaaatta
     1141 taagcttttt ttgtgtaatg cgaacggcag tgcggaaaaa gaaaaagaat atatccaaat
     1201 ggtcaagcag agtaaagtag acggaattat aggtattacc tattcagaca ttgataaata
     1261 tgtatcatca aatttaccat ttgtcagtat agaccgccat ttttcggaac aggtttctta
     1321 tgtaacggca gataattatt taggtgggca aattgccgct caagaactac ttactcgtaa
     1381 ctgtaaaaac ttgtgctatg ttgggggtgt ttcaccttac cctaacgaaa caaacaatcg
     1441 taaagctggt ttttacaata tttgtgagga aaataaaata gctgtgaagg tattggatat
     1501 gcctgaacca attagcaatt tggaggaaca attgctcgct tttttttcgg ataatcctga
     1561 aattgatagc atttttacca tcaatgattt catggctttg gatgtgataa aagcccaaaa
     1621 aaaactaggg aaggaagcac ctaaggattt tcaaattatt ggttttgatg gagtcaagct
     1681 atcgttgcaa aaagactatt tactatcaac gattgtacag ccgatagagg aaatggccaa
     1741 ggtttcagta gaaacactca tggcgatgat tttaaatgaa gaaccgccta agcgtgtggt
     1801 agtaccggtt ttctttcacg ctggagaaac gactaaagag taaaaaaccg gtttataacg
     1861 attttttttg agataggttg acagaaagtg gtttcaatga tatcttaaaa ccaattaatt
     1921 ggaaacgtta ccaattaatt ggaaaataaa acggaaacgt ttcaaaaaat aggaggaaca
     1981 tcgatgaaaa ggagaatgtt agcaattgca gcaattttag cattaacagc tggaggactt
     2041 gcaggatgtg gcagtaagga gaaaagttca ggcagcagtg attcaggaga aattaagatt
     2101 tgggttcagt tttctgatga aacgcctgaa ggaaaagctt gggcagagat tgtgaacaat
     2161 tttaatgatg aatacgaggg tgaatataaa gctgttactg agtatattcc tcgtagcgga
     2221 agcggcggtg gatatgagga taaagtaaat gctgcaatta caaccaatac ccttcctgat
     2281 gttattacgt tagatggacc gaatactgca gcttatgctc attcaggagt cattgctcca
     2341 ttagatgatt atttgaaaga tgcggacatg gatgatgtat tagacagcat tattcagcaa
     2401 ggaacctacg atggcaaaat gtatgcgttt ggtttctcag agtccagtgt gggtgtctat
     2461 tacaataagt cgttgttcaa agatgctgga attacagaag atcaattgcc gacgttagaa
     2521 gatccttgga cttggacgga atttcaagca atttgccaaa agctgactga taaatacaaa
     2581 acgcctgcaa ttgatatgca aatggcgtcg ggagacgaaa tgctgaccta cgcatataca
     2641 ccatttgtat ggtcgaatgg cggcgatgtc gttaatgctg atggaaccaa agccgaagac
     2701 tattttaacg ataaaaaatc cgttgaagcg ttggaattta ttcaagaatt ggttgaaaaa
     2761 ggttacacca caatcagtcc tattgaaaaa ggatttgaaa ctggcaaata tgccatgctg
     2821 ctgagcggtt cttggacaat ggcagattta gaggaaaact atcaagagat tgattatggt
     2881 attttgcctt accccgtttc agatgcaact ggggagttag tttcaccaac cggcagctgg
     2941 cagttagcaa tgactgagaa aacagagaaa aaggatgctt ctgcggcctt tattaagttt
     3001 gcaaccagta cagaatctag tcgtattatt agtttaggga acagtgttct acctatcaga
     3061 aattcaacag ttgatttaat taaagatgaa gtgtcggaag gaatgcaggt attaattaag
     3121 caaaaccaaa tttctggaca tgcccgccca gtggttgtag cttatccgca agtatctaga
     3181 gcattccaac aagcagttca agatattagc tacttcgagg aaaacccaga tgtacaaaaa
     3241 gtagcagata gtcgcgctgc tgaaatgcaa caggcaattg atacttcact aaaatagaag
     3301 tttctaaagg gggccaatca agtgttaaaa aaaccgacaa tgaaagacaa tttgataggt
     3361 tacggctttc tagcgccagc tttgctgctg ctgacgattt ttctgatcat acccgtaatc
     3421 atggtaattt attatgcctt tactgattat tatttgttaa cgccagatgc tagacaattt
     3481 atcggcttag aaaattttaa gcgactgttc gctgatccaa tttttgtaaa aagtatttgg
     3541 aacacggcta aatttgttgt ttggattatt ccggtccaat taggggcagc tttaggaatg
     3601 gcacttatta tcaacaaaaa tcgtaaagga aatatctttt ttaaagtagc cttttttgcg
     3661 ccagtcgtga tgtccttagt cgttatttcg attttatggt tgtacttgtt aaatcctaat
     3721 gaaggtctgg ttaatacgct atttgcaaag attggaattg cttcgcagcc ttttttgact
     3781 agtcccaaac aagcaatgta tacgcttgtt ttcgtatcgg catggcaagg tgcaggatat
     3841 cagatgctgc tgtttttagg gggaatgcaa aatattccgc aagacgttta tgaggcagcc
     3901 gaaattgatg gtttttctaa gtttcagcaa tttcgctata tcaccatgcc attattaaag
     3961 cccacggcga tttttatttt acttaccaca ttgatttcgg cctttaaact aatcattcag
     4021 ccaatggtaa tgactcaagg tggaccaatg aattctacta tgacaatggt ttattacatt
     4081 taccaaactg gatttacaga ccgtatggta ggctactcca gctccattgc gttaatcttt
     4141 accaccatga ttggtttaat tacaattgct caaagaaaat tggtaaagga ggatgatcca
     4201 gcatgaccaa gaaatttgga ccgctaatga tcgtagaata ttgtttgctg ttccttttag
     4261 cggcattatt cattttccca atgctgtgga tggtagtttc ctctatgaag cctgaagcag
     4321 atgtctatca aaatttagct tccttcaaag cttttttacc tagtttgaat ccagctaatt
     4381 ggtttaaaac ttatcaagaa gttatttccc ggttcagtgt gggaacttat ttattaaaca
     4441 gtatttttta tggtttaacc tttgcctgtg ggtcaatcat tgtaaactct ttggcgggtt
     4501 ttgcctttgc gaaggttaat ttttcaggca agaaaattat ctttggagct ttgttagctc
     4561 tgctgattgt cccgatggag acggttttaa ttccgcaatt taccatcgtt aattcactag
     4621 gcttagtgaa tactcgcttg gcagtgattt taccagcgat ggccagcgcg tttaatatct
     4681 atttgtttag aaatttcttt atcgcgattc cagaagaaat cattgaatca gcgaaattag
     4741 atggtgcaaa tattgttaaa attttctttc acatcatgct gccaatgtct aaaccagcca
     4801 tagccacagt aggtgtctta tcctttatct ccagctggaa tgattatatt tggccgttaa
     4861 tggtcttaac tgacagcagc aaattttcaa tgcaagtggc aattactacg atcaatacta
     4921 cacagccagt ttatatcaat caagtgatgg ctgttttaac cattgcaacg attccactga
     4981 ttattgttta tatcgttgca caaaaatata ttctgcaggg acttggcggt tctggaacgg
     5041 gtataaaata ggagtgaata gtgaatgttg caaaaacttt taaaggccaa tgagtttatt
     5101 gagaaaaatg ctcaaacagt caatcaagaa taccggaata aatttcattt gatggctccg
     5161 attggctgga tcaatgatcc aaatggtttt gtttattatc aagaggagta tcacttgttt
     5221 tatcaatatt atccttacga tagcatctgg ggaccaatgc attggggcca tgctaaaagc
     5281 aaggatctaa ttcactggga gcatttgcca gtagcactgg caccaggtga aagctatgac
     5341 aaggaaggct gtttttccgg cagtgccata gaaaaggatg gcaagctgta tttgatttat
     5401 acaggacaca atgttgtgga agggcaagtt cgacaagttc agtgtttggc agtttcagaa
     5461 gatggcattc actttgaaaa atatgccgga aatccaatca tcgcagaaga tcacttagct
     5521 tctgttgcaa cgaccgaaga tttccgcgat cccaaagtgt ttcagcgaaa agaagactat
     5581 tttactgtag tcgctactaa aactgcagat gctcgtggac aaattgtgat gttccattcc
     5641 aaagatttac taacttggga gttttattcc gtattgctgg agggaactcc agaacaaggc
     5701 attgtatggg aatgcccaga cttgtttgaa ctagatggca aagaagtctt gattctttct
     5761 cctattcaaa tgactccaca aggcaatgct taccaaaata cgaactcaac tgttgctttc
     5821 attggtactg tcgattggca aacaggcaaa tttctagtag agaattttca tgaaatcgat
     5881 ggcggtttag atttttatgc cccccagacc tgtgaaaacg aagcaggcca aagaataatg
     5941 actgcttgga tgcaaatgtg gcagcgtaaa atacctacga atgatctggg ccatggttgg
     6001 tcaggttcca tgaccttgcc tagagagctg agggtggctg ataatcaatt gttgcaacgg
     6061 ccagtttcat caatttatca agtaattgat ccgcaggaaa ggattgaatg ggcgaagact
     6121 gaagagaatc gattcttact gaagggctta gtatatgacc agcactattt acgcttggaa
     6181 atcaatttaa aacaggcaac gaaactagaa cttcactatg cgaagggacc ccaccataca
     6241 ttactgctta actatgatgt tgaacgggag tgctttactg cttccaggga acacatgccg
     6301 tatgatttat caggagctga aaaggaagtg ttgaaaaagc gcagtgtgac gattcctttg
     6361 gaaaataatt gtctaaccat cgaaattttc cgtgatactt cagctattga gctttttcta
     6421 aatgatcgtc tgactatgag tacaactttt tatgagacag aaaaaggaca ggattttctt
     6481 ttgctggcag acagtgaagt aaccttttca ttggaaagcg gcttaattaa tctatagaag
     6541 ggagagctca gtgatgattt atggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc
     6601 cattggcgat gaagaaatga cgatcaagga aagagtgagc tttccgacaa cgacacctga
     6661 ggaaacaatg cctttagtca ttgacttctt caaacaatac caagcagatt tagcagggat
     6721 tgggattggc tcatttgggc ctatcgatat ccatcgcgat tccgccactt atgggtacat
     6781 tacctcgacc ccgaaattgg catggcaaaa ttttgatttc atcggtacca tgaaaaaaga
     6841 atttccgatc ccgatttctt ggacaacaga tgtcaatgcg gctgcctatg gtgagtatgt
     6901 cttcggcagt ggcaaaggat tgagcagtgt cgtttactat acgatcggta cgggtgttgg
     6961 cggcggtgcc ttacaagaag ggcgctttat cgaagggttt agtcatccag aaatggggca
     7021 tatgctcgtc gtccctcatc caaaagatga ctttgctggc agctgtccat ttcatggcaa
     7081 ctgtttagaa gggatggccg ctggacccgc catcgaaaaa cgcttaggga aaaaaggaca
     7141 agaggttgca gaagatgatc cttattggga aatcgaagcc tcctatattg ctcaatgtgc
     7201 ctacaataca accttgatgt tttctccaga tgtgatcatt tttggcggtg gtgtgatgaa
     7261 acaacgccat atgctgcaaa acgtccacga cgcatttgca aaattggtca atgggtatgt
     7321 cgaaacacct gagttaagca aatatatcgt gaccccagca ttagaagaca acgctggaac
     7381 gctcggttgt ttggcattgg ctcgagaagc ggtcttacat tcataaacga aaaaaggctc
     7441 ttcgacattt agtgttggta gagaaagata caactgaaaa tttagtcata accagttagg
     7501 cagagtgctt aactggtttt tgttttactt ggaagatcaa gccttgaatg agataaattc
     7561 ttgctcgaaa gttatggaaa tttcgatagc cgtaggctac ttgtattgtg caatagtttt
     7621 ttacaaaaaa aaggggtgcg gatatttttt tggacctttt taacaaatat atctttgctt
     7681 cttccgatat tgaagagggc ttagccctcc taaagataac ttaattcgtt gattattata
     7741 ccaatgaata taattatcca atttgtttat aaactgattg attgttgtat tcttccagtc
     7801 acgttgataa aacatctcgt tttttaatcg tccaaagaaa ccttcgcacg ctgaattatc
     7861 tggtgaataa ccctttttag acatagagtg aagcaagttg tctttgttcc aatagtccaa
     7921 ctaacaatag caccatcgta acaatcgaca agtggtgata agtagatttt ccctgcggga
     7981 attctaaatt cagtaatatc tgttaaccat ttttcatttg gcttctttgc tttaaaattc
     8041 cgatttggat aggctacaat taactatata ggttgaatta aatactttac atccgcacgc
     8101 acagtcggtc aatcacctca aggggacgct cgtttacatc ggctaagaaa ccgcggaccg
     8161 actgtttgat tttctggacg tggtcaaaaa aaacattgtt gatgaccgat tccttgagtc
     8221 acttccaaac gccttccatt aggttcaact gagg
//
LOCUS       DAIGUC010000084         8229 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.086, whole genome shotgun sequence.
ACCESSION   DAIGUC010000084 DAIGUC010000000
VERSION     DAIGUC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.086"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            329..1252
                     /gene="truB"
                     /locus_tag="NOB46_002557"
     CDS             329..1252
                     /gene="truB"
                     /locus_tag="NOB46_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCI1059458.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1256..2197
                     /gene="ribF"
                     /locus_tag="NOB46_002558"
     CDS             1256..2197
                     /gene="ribF"
                     /locus_tag="NOB46_002558"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HCI1059459.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2592..3377
                     /locus_tag="NOB46_002559"
     CDS             2592..3377
                     /locus_tag="NOB46_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1059460.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3390..4241
                     /locus_tag="NOB46_002560"
     CDS             3390..4241
                     /locus_tag="NOB46_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCI1059461.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4365..4817)
                     /locus_tag="NOB46_002561"
     CDS             complement(4365..4817)
                     /locus_tag="NOB46_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059462.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5282..5650)
                     /locus_tag="NOB46_002562"
     CDS             complement(5282..5650)
                     /locus_tag="NOB46_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HCI1059463.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5800..6282
                     /locus_tag="NOB46_002563"
     CDS             5800..6282
                     /locus_tag="NOB46_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HCI1059464.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6319..7329
                     /locus_tag="NOB46_002564"
     CDS             6319..7329
                     /locus_tag="NOB46_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCI1059465.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7444..8157)
                     /locus_tag="NOB46_002565"
     CDS             complement(7444..8157)
                     /locus_tag="NOB46_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059466.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2785 a         1337 c         1667 g         2440 t
ORIGIN      
        1 attaagaaac tgaaaaaata aataaaaaaa aacggaaaaa agactggaag aatggacagt
       61 cttttttttc gtttttggga agtgaaaacc aaactattta cctgtaagcc acccataaat
      121 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaaaacata
      181 acatgatttc tatttacgtg agcatgaatt ttgttacgtt tttattgccg aaaaataaaa
      241 accgttcatt atgatgtcaa attcgtcagt aattgatgca atgtgttata ataattcagt
      301 taaatcaaaa atgaaatgga gaaaagacat ggacgggtta ttaactttat ggaaagaacg
      361 cggaatgaca agtcatgatt gcgtattcaa attaagaaaa atcttacata cgaaaaaaat
      421 cggacatggg ggtacgcttg acccagacgt agacggtgtg ttgcccattt gtattggaaa
      481 agccacaaaa gttatcgaat atttgacaga ttctgggaaa atctatgtag gcgagataac
      541 tctaggtttc agtacaacga cggaagatcg atccggagaa cgggtagaaa caaaaccagt
      601 agatatgtct ttatctgaag aaaaaataga tgaagtgatg gcttcattta ttggtgagat
      661 cacccagata ccaccaatgt actcagcggt aaaagtcaac ggtaagcggt tatatgaata
      721 tgcccgcaat aatgaaacag tggagcgtcc tgttagaaag gctcagattt accgttttat
      781 ccggacaagt gaattgacaa gagacgaagt gacaggaacc atttcttggc gcttcgaagt
      841 agaatgcggg aaaggaacct atgtccgcac attagctgta gatacaggca agaaacttgg
      901 ttaccctgcg cacatgtctg atctgacccg aacagcaagt gccggtatgt cccagaaaga
      961 tgctctgaca ttagaagaag tagctcaagc tgtgaaaaat gggacaatcg atgattgttt
     1021 gctgccaata gaaaaaggag tgaaacgatt caaacgagta gatattactg atgaagtatg
     1081 gcagaaagta aaaaacggta tgagacttaa ttatactgta tttgcgctcc cagaaatgcc
     1141 gtcagaagaa attgctttgt tttataaagg caaagttgtc agtatctatc agccaaaccc
     1201 gaaagaaaaa aacaaattaa aacctagtaa agtattgaga aatgaggaat aacgaatgaa
     1261 tatcatcaag atcagacatc cttaccaatc agaacaaatt ccagaagacg atgtcgtttt
     1321 agtactagga ttttttgacg gcgtgcatat tggacaccag aaagtcataa agacaggtat
     1381 ggaaattgca caaaaagaag gattgaaatt agcattgatg actttcaatc agcatccatc
     1441 gattgtcttt aaaaagatcg atcctagcag cgtgaaatat ttgactagcc ttaagcaaaa
     1501 agaagaaaaa atggccgctt tgggtataga ttatttatat gaagttgatt ttacttcttc
     1561 ttttgctcat ttagcaccgc aggaatttgt tgatcaatac atcgtagggt tacatgcaaa
     1621 atatgctgtt tccggttttg attatacgta tggaccaaaa gacattgcag atgtcgctca
     1681 ttttcctgaa tatgccaaag gaagattcaa aatcgtcaca gtttctaaag aagaagaaca
     1741 aggtgaaaaa atcagctcta cccgtattcg aggattacta gacagcggac aagtaaaaga
     1801 agcagcaaaa ctattaggtt gcacatatga ggtagaaggg gtagttgtcc atggcgatgc
     1861 acgaggcaga ctactaggat tccctacagc aaatgtcaaa gtaaagagca cagttcattt
     1921 gcctaaagaa ggtgtttatg tatcggaaat aaaaattggg gaaatttggt atccagccat
     1981 gggttcaatt ggacataatg atacattcgg tgaaggacgg gagctgactg tagaattgta
     2041 tattttggac tttaatcaag atatctatgg tgaacatgtc gcagtacgct ggaatcaatt
     2101 tttaagagat caagtgaaat tttctagtgt agaggaattg attgaacaac tcaaagagga
     2161 tgaacaagca acagctgaat atttttctca gcaataaaac attatgcata aaatctcttg
     2221 tttatgtata actagcaatt tcaataaaat gggtgataaa taagcccagg aaaggggctg
     2281 tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga agtagcttct
     2341 tcggaaataa gccgaaattt cacaaaaatt tgagaagtaa tttttgtaaa ttacttctta
     2401 tttcttgaag ctggccactt ctgtcacaac ctctttcttt atagaaataa aaggacacta
     2461 gcaattcatg aaaacgattg ctaaagcgta tcatttgctt tagactatat atcttggtgt
     2521 acactcactt taagacggaa ataaaagtta tccgtaataa caggtttagg tatgaaaaag
     2581 gagtgggtac tatgtataag gaattagaaa acaaagtcgc agtagtaact ggtggctcaa
     2641 aggggattgg aacagcgatt gctcaacgat tcgggaaaga aaaaatgaat gtagttgtca
     2701 actataactc ggataaagaa ggagcagaaa aagcagtcaa agcaatcgaa gaggcaggcg
     2761 gaaaagcagt ctctgtacaa gcagatgtca gttctgaaga aggaatacag cgtttacttg
     2821 atacggcttt agaaaatttt gggacactgg acgtttggat taataatgct gggatggaaa
     2881 atcagcatcc aacccatgaa cttagccttg aagattggga aagagtatta aaagtcaatt
     2941 tgactggcgt ttttatcgga acgaaagcgg ctttaaatta ctttacagag aatgataaaa
     3001 aaggaaatat catcaatatg tcttctgttc atgaacaaat cccatggcca acgtttgctc
     3061 attacgctgc ttcaaaaggc ggagtaaaac tattcaccga aacggtagca atggagtacg
     3121 caccaaaggg aatcagaatc aatagtatag gacctggtgc tatccgtaca cctattaatg
     3181 cggcaaaatt tgatgatcct gaacaaaaag aactcttgga aagtatgatc ccactaggac
     3241 gcgtaggtga accaaaagaa atagcggcga cagctgcatg gttggcttca gacgaatcca
     3301 gttatgttac aggtattaca ctatttgcag atggtgggat gactttatat ccttctttcc
     3361 aaggtggaaa aggataaggg tgaataaaaa tgggtttatt gattgcattg atcccggcag
     3421 ttgggtgggg gatccagcca ctgattttga aaaagattgg tggcagacca acaaatgaga
     3481 tattaggaac tggtattgga gccgtgctcg ttggcttact tgttcaatta ttcgcttctc
     3541 cagctggtat ttcagtgact acatttttga ttagtttact ttctggtgca ttctgggtca
     3601 tcggacaaac aggacagtat acatctttca acttgattgg tgtttctaaa acgatgccaa
     3661 tttcgactgc attacagtta gtcggaacct cattgattgg tgtcttcgct tttggagaat
     3721 ggtctggaag tatgggaaaa atcattggtg cagcagcaat cattcttctt gtatttggtt
     3781 ctgctttaac ggcaatcagt gatgatcctg gaaaaaaagg cggtatcaca aaaggaatca
     3841 gtctattagc atcaacaagt attggttatt gggtttacag tgcattgccc aaactagttg
     3901 atgcaagcgg actttccatt ttctttccgc aaatgatcgg tgtcttttta ggggcagtga
     3961 tttatgtgat tttccgaaaa ccaaccgcat tttctgaaga caagagttgg aaagcaacaa
     4021 tagttggagc catcttcagt gtgtcagcat tggcttatat tttttcagca aatgaaaatg
     4081 gggttgctac tgcatatatc attacacagc taaacgtagt tatctctaca ttaggcggta
     4141 tgtacatcct gcatgaaaat aagacaccaa aagaaaaaaa attaacgatt atcggattat
     4201 tgctgatcgt agtaggaagc atggtcacgg tctttatttg aggataaaga tggtaaaatc
     4261 tcatttatta aaaaaatatt tgtttgaacc aaacagtaag tacttataaa aaaatagcgc
     4321 tagaatttcc aacatctctg gaatttctag cgctttttaa ttgtttaaga tacaagtgaa
     4381 atatctgtct gcatcaataa tttttcattg atccattgac taaaatttac gacatgattg
     4441 aagttaccac cgattagtat ctccgcatga ttgtctttat aaagatcgta ttgtaaaaga
     4501 cggtcttttt tatttgcgta aacatcgtta tggtactgga ctaattgttc tcggatttga
     4561 ttgattgctg taaaatcacg atactgaagg ttgaaacgca tcgtgattgg tgcatttagc
     4621 atgaatcgct gcatttcttt tgctgcttcc tctgcttgat ctccgtatag gaactcaaaa
     4681 agattacgtt cagaaaattt ccattgcccg ccaacctttg ttccttttag ttttccttca
     4741 tgaagataat ttctgataga acgtgtagta acacctaatt gttcggctaa ttcatttact
     4801 gagtaaaaat ctttcaatgt tcaccctcct atgtgaatgg ttctactgac ttagttgata
     4861 tttgcttaat cacgaaatgt agaaagaacg attttaatta aggtcattgt aaaaatcaag
     4921 tcagaaaatt ctaacttttc tttctctaaa gaaattcgtt ctctcctaaa gtgatattat
     4981 atttaaatat acctgaaaat aatgggcagt attatgaaag atcactgata ttttctcgta
     5041 ttttttcctt attcaaaagt tttgcaggaa aattgctgaa aaaataattt tactaagtgg
     5101 aaaattcaaa gccattcaat cagtgatttt tttcagcaca agaaagactc cttataaaaa
     5161 tagcagatac tttgtcaatt aagtgtttaa ccagggatga taaaaaggat aggattgaac
     5221 aaaacctgta taagctgatg aatagtttcc tcgccagtaa aaggtttatt cgtataaagc
     5281 tttatcgcca aaatttatca tgaccttttt tatcttcaat attaaatgaa atcaattgtt
     5341 caatcaattc ccagttgatt acacttttcc aaggaacttt gatgacgtta tccgtatata
     5401 cgtagcctgc ttcttggata tttttttcaa gggcacgaat cgctgctttt tccggtgcga
     5461 tagaaaaatg atttttagca aaactaaatg caataataaa ggtaccatgg tcagtaaaca
     5521 taggttggtt ccattttaca gttgtgtcta gctggggata cgtttctgtt atcttagcaa
     5581 aaaggtcttt gatcttttgt tgatgttctt tttctttgat ctgattgatg atcggctgaa
     5641 atttttccat tctaaaacgc ctccattaag tggtttgatt tattttacca gaaaaacaat
     5701 agttatgtat aaaaaacgaa caaaacacaa gtaatgttgt aaccgctata tttatatgat
     5761 aagatgtctc aaataataaa atagaaaaga gacataaaaa tgattgactt ggcaaagaaa
     5821 ttcttacacg aaaatatata ttttgagttg tatcatcatc gagccattta tacaaatgaa
     5881 gatgctttgg taataaagaa agaacaagga tttacaggta cagagaccaa aagcttattc
     5941 ttaaaagata aaaaagataa taactacgta tatctgactt ttactacgaa acaaacggat
     6001 ttcaaagcat tagggaagat cgtcggtaaa aggctttcta ttgtttcatc agaacgcatg
     6061 gaagaacaaa cgggacaaaa gcagggcgct gtttctccgt ttggttatga aaaacagatt
     6121 ccgattatta ttgatgaaga gctcttatca aatgaaaaac ttgtttttgc accaggtaga
     6181 ccagatcaaa cgatggtcat ccaaacggtt gacttaaaca aaatcatcca gctacttgag
     6241 atgccgatat ttttgatgcc ggcaaacgaa aaaaacaatt aaccaagtaa aatagtgcat
     6301 acttggaggt gaagcaacat gataagttat ccattattag aaagaaatgc aacgattggg
     6361 gttactgcac catcctcagg cgtatcagag gaacaccatt cgttactcga atcagcttta
     6421 aagagaatgg aagaaaaatc tttccaagta gttactggaa agacgctttg gacgcaagat
     6481 aaggaaaaat caggtccagc aagaaaacga gcagatgaat tcaatcaaat gatgcaagat
     6541 gaaaatatcc aaatgatctt tccgccttgg ggaggagaat tattgattga gattctcgat
     6601 tttgtcgatt ttgatgctct acaaccaaaa tggatagtag gttattcaga tattagtacg
     6661 ttgctacttg ctgtcacatt aaaaacaggg atagccactg cacatggaac caaccttatt
     6721 gatttaagag gagagtactt ggatgaaacg acagcaatgt gggaaagtgt actgaaaaca
     6781 agagaaggag aatcgattct acagcaacct tctgaaaagt atcaaaaaga gtggccccat
     6841 gagcattcat catcttctgt tttccatctc actgaaccaa caaattggca atcagtcagc
     6901 ggagatgcag taaggatgaa gggacgatta ttaggtggct gtattgatac gatcagtcat
     6961 ttaatcggta ccccttatgg agatgtccaa tcttttaaaa gaaagtataa tgatggaaag
     7021 ccgatcttgt ggtttctaga aaattgtgag ctatcgtcag ttgatttaag aagatcactt
     7081 gttcagatga aactggcagg atggtttgat ggcagctcgg ggatcatgtt cggtagaagt
     7141 gcagcagagg atttgttaga ttataaaatg aaggatgtat atgaagatct gtcaaaggaa
     7201 ttaaaactac cgatcttgta tgatattgat tgtggtcatg taccgccaca actgacattg
     7261 atcaatggtg cctatgcaga agtagcggta gaagatagaa aagcgactgt tttgcaaacg
     7321 tttatttaaa aaattttttc ctgccttgga gtttatcaaa gaccaacaaa tctaaataga
     7381 aaagaaaatg aaagaagctg acagtatttt gccagcttct ttttgtatga tctattagaa
     7441 attttaatta tccataacta tcacattgat cagctgtttc acatcatttg gattacctgt
     7501 aggaatagct actacagatg cattatcaat aatttcttga gttgtttctc taatgaacgc
     7561 tggataagat gtttgatctg caggcatttg ccaatgtgaa ggaactggat aactagtgat
     7621 tgtcccgtca tggttacttg aatacactaa aactccctgg taactgtatt tcccagtgag
     7681 cataaccaca tctttcggat agactgcact ccctgcatca taaggggcga taggtgttcc
     7741 tgcaggataa tgaataacat gtagttcgaa atcacccgat gtatctctaa aagtattacc
     7801 tctaattgct agccaaacac gtgcgtactc aatttgtaga tcagaatatc ctgctaacgg
     7861 atctattgac tgagaagact gtgaggaagt tgtgtctatt gttgaagaag aaatatttgt
     7921 ctcaactgta ctactagatg tagaagaagt attgggctct gagactttac tgcttgttga
     7981 agatgtattc gtttcagtag aagctgattt ctgagtactt gatttttcag ctgaactggt
     8041 ttgtttgatt gaacttttgt ctgtggtcgc agatggatca ctattttctt tactaggaga
     8101 cgtacatcct acaaggaata aagagaccaa caataaaata aaacctaact ttttcatata
     8161 aaatacctca ttattttttt aataccagta tagcataatc ctgaattttt gaatccgtaa
     8221 aaccttgtc
//
LOCUS       DAIGUC010000085         8103 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.087, whole genome shotgun sequence.
ACCESSION   DAIGUC010000085 DAIGUC010000000
VERSION     DAIGUC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.087"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            121..1068
                     /locus_tag="NOB46_002566"
     CDS             121..1068
                     /locus_tag="NOB46_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCI1059467.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1136..1429)
                     /locus_tag="NOB46_002567"
     CDS             complement(1136..1429)
                     /locus_tag="NOB46_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HCI1059468.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(1457..2122)
                     /locus_tag="NOB46_002568"
     CDS             complement(1457..2122)
                     /locus_tag="NOB46_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCI1059469.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(2262..2894)
                     /locus_tag="NOB46_002569"
     CDS             complement(2262..2894)
                     /locus_tag="NOB46_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1059470.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(2901..3968)
                     /locus_tag="NOB46_002570"
     CDS             complement(2901..3968)
                     /locus_tag="NOB46_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI1059471.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(3965..4696)
                     /locus_tag="NOB46_002571"
     CDS             complement(3965..4696)
                     /locus_tag="NOB46_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HCI1059472.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(4864..5343)
                     /gene="greA"
                     /locus_tag="NOB46_002572"
     CDS             complement(4864..5343)
                     /gene="greA"
                     /locus_tag="NOB46_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCI1059473.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(5479..6654)
                     /gene="mltG"
                     /locus_tag="NOB46_002573"
     CDS             complement(5479..6654)
                     /gene="mltG"
                     /locus_tag="NOB46_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HCI1059474.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            6819..7979
                     /locus_tag="NOB46_002574"
     CDS             6819..7979
                     /locus_tag="NOB46_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI1059475.1"
                     /translation="MSKGKHRKKQKISISFLVILLLSVSFFSTGIIIGGQLTKIPHSQ
                     TYKAEPTQLTSNLTPDEQRLASKIDQLLQKSDYIGSIYVRKNNRVLLEKGYGYANLRV
                     KESNSPSIYYQIGSIQKAMTALLILKQIQAGKLTFDTKLAEFYPQIPGSQQITIKNML
                     YMRSGLHRTASPDKPMSDSEIIQFALHHLKLTDYDTYHYEPLNYTLLTGILIKLTNQP
                     YETLLKKEIIRPLHLEHTDFYDNVKNSPQHAVSYQMSATDDYSKALIEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGGIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVVAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVHLSN"
BASE COUNT         2428 a         1679 c         1282 g         2714 t
ORIGIN      
        1 ttttttgtca cagccccttt tttatttgaa aaatatttct ttctcaaaaa acaagcaagg
       61 cgcttcaaag ttcttcttgt atgcgctaca cttagagtaa agaaaggcgg gaaattaact
      121 atgtcagaaa gaatcattta tgcagatcgt ccatttcgtg atgaatttat cgaagaaatc
      181 catactatag cgcctggtta tatctttaaa acagaattac aaccagagga tctacaaaat
      241 gtagagatca gtttgggctg gaactcagac taccaagaaa aactattagc ctcttctacc
      301 ttgaaatggg tccaatctat ctcagctggt gttgatcagc taccccttga gactttttca
      361 aagaaacata ttttactttc aaatggtagt ggcatccaca gtgaatcgat tacggagcat
      421 gtcttaggaa tcatccttgg gtattctcgt ggtctttttc aagcacaaaa ggcacagagt
      481 gacatgaaat ggttaggttc atcggtccat taccaatcta tccaagggaa aaaaatacta
      541 atcattggaa ctggccatat tggaaaaatg attgcaaaaa aatgcaaagc attagacatg
      601 aactgctatg gaatcaatac atccggtcat ccagcagaag gaatggaaaa gactttttct
      661 ttaaatcaac taaaggaagt tcttcctgaa gtagatttcg tagtcaatat cttacctcta
      721 acggaggaaa caactgggct ctttgatcag catatgtttg aacactttga tccaaaatct
      781 gtattcatca atgttggccg tggtgcttct gttaagacac aagatctggt gcaggcttta
      841 aataaccagc aactttcctt tgcagcatta gacgtttttg aggaagagcc tcttccacaa
      901 gatcatcctc tttggaaaat ggacaatgta ctgattactt cccacattgc aggtttgaca
      961 cctgattttc aaaagaaatt aatggctatt tttttaacca atctgaaaag ctactttgcc
     1021 acccatgagc ttcaaaccaa tcaagtaaaa ttgtctgcag gatattaata gctgaaaaca
     1081 atattttcaa aagaaaaaag agaaggtgac aaaaattgtg tcaccctctc tttttttatt
     1141 gttttttaaa gtgataggtt ggctcctcca ggttgggatc ataatcaaca agtaaatcat
     1201 atcctttaaa gaaccattca tctgcttcct cgataaaaaa aagtgtccca tccatttcca
     1261 ctttctttac aggatgttct ggctgttcaa ctgacattcc aatcgaaaaa ccatcatgaa
     1321 cctctgtttt gccgtagact tttccaaaaa aacgtattcc gtaagtttct ggcagatcaa
     1381 tttctgagtc aaaccatttt tgtgcttttg gcgttaccgt taatttcatc ccaacaacct
     1441 actttctctt ttctttctat tgattcatct tatcgtctag aatatccaca tcgcctgtct
     1501 ctccaataac cagtagatta tcattttcac gaacatattc atctgctgca ggagaagcga
     1561 taaccgtttg atctactctt cgtatggcga ctactgttaa gtcaaaacgt tgcctgaaat
     1621 ttaattcagc taatgttttg ttgaaaaatt taggattgga gactcggatt tctgctaaag
     1681 aatatttatc tgacagctct aagtagtcta gaatattctt tgatactaag ttatgtgcaa
     1741 tccgtatccc catgtctcgc tcagggtgta cgacacgatc tgctccgatc ttctctagta
     1801 cacgggcatg gtactcattt tgggcttttg ctaaaatatt cggtacgccc atttccttta
     1861 ccatcagagt aactaagatg ctggcttgga tatcttctcc aatagcgaca attacatgat
     1921 cgaaatttct tatacctaat gaacgaagtg tcatctcatc ctgtgcattt gccacaacag
     1981 catgggtggc tatattcata tattcattga ctcgatcttc attactgtca atagccagta
     2041 cttcttgtcc agcttcgatc agtgtacggc agatgcttcc gccaaatcgt ccaaggccta
     2101 caattgcaaa attttgtttc accattttcc tcctttagta tcttcttttc tcagtataac
     2161 aaagcctttc caaaaacaaa agcaagcatc attattgtaa aaaagccaag aaaaataata
     2221 gttattttct cagcttttga ttatcctctt tatcatcgtt tttatttcac caaaccatgt
     2281 ttaaacgcat agatagctgc ttgagttcgg tcttctacct ctaacttagc taatatattc
     2341 gacacatgcg ttttgactgt tttcagtgtg ataaacaatt catccgcgat ttcctgatta
     2401 cttttccctt cagaaatcag catcaaaatt tcattttctc gattcgttaa ttcttcatgc
     2461 aatactggat catttcgccg actcattttt tccatcattt ttgttgtcac ttcaggttct
     2521 agtactcgct cgccgcgttg cgtagccctt atagcatcag ctatttcatg tgctgtagac
     2581 gtcttcaaca aatatcctgc tgctcctgct tcaattgcag gataaacttt ttcatcatca
     2641 ataaaacttg tgacgataat gattttggct tttggccaat cttttaagat tgcttttgtt
     2701 gattcgatgc catccatttc ttccatgact agatccatta aaatgacatc cggtcgaagt
     2761 gccatcgcct tttcatagcc ttgacgtcca ttttcagctt ctccaatcac ttcaatgtct
     2821 tcttggatag ataaataaga agagacgcct aagcgtacca tttcatggtc atctactaat
     2881 aaaactttta tcatctttat ctatgcctcc ttcatcaaag ggaccttggt ctccacgctc
     2941 gtaccttgcc ctttaaaact aatgattttt actgttccac caataccagc tactcgttct
     3001 ttgatattgt tcaatccata acttcccgtt ttggtttcat tcatattaaa tcctgtcccg
     3061 tcgtcaatga tacgtaataa aagattgtta tctattttat gcaaatagac ttctaattca
     3121 ttagccttag catgtcttaa tgtgtttgat aacaattctt gaacgattcg gaacaagtga
     3181 tcctcaatgg aactagttaa ttttacatct tctacctccc attttagcga aatctggatt
     3241 ttattctgca attccttcaa taactgctca atgccttgtt ttaaactttt ttcttctaaa
     3301 ttgactggac gcagatgaag aagcagcgca cgcatctcag actgggaagc gttgatgatc
     3361 tctgccacca ttttcaactg cttacggaac atttctggtg tctcactttt ttctgcttgc
     3421 tccgtcaatg ccgacatcat catcatcgct gcaaataatt gctgtgaaac tgaatcatga
     3481 agctcacgag ctaatcgatg cctttctaat tttaaaatct cttctttggt ttgtccatct
     3541 acatattgag gacggctagt cataatctgt aattcactgg atacttcgat cattttttct
     3601 tttattttag taatttccat atcaatatct ttgatgtaca gatcatccga cgcgcttggg
     3661 atcggctgat gcaaaagttt ggattcataa ttgccagaag aaagtgcacg aagcttttct
     3721 tcgattttcc cgtattttgc cttttgaata agtgataaca atagaaatac gatcaatcct
     3781 acacctaatg aaattgccat caaatggaag ataagcggaa cgtataataa acgcgcacgc
     3841 agcaattctc cccaccaatg actttggtta ctggcataaa aataagtgaa aagtgaaaat
     3901 agaataataa ggaaagccgc aatccccgaa taaacagcta gcattgcttt ggatattctt
     3961 cccatcatat tcgtatcacc tcgacatctc caaccaaagt attggtaatg atcttcaatc
     4021 tgcgaggatt ttcatcataa tcactgctgc agattttgat ctgttcgttt tttaaggaaa
     4081 actgctcttc ttcaaacaag acatttccta ctaatgtcgc atgctctaaa cgaatagcca
     4141 ctcccagggg tactaagatc cgtgttctgc ctatcccttt tcttacaatc acaatattat
     4201 catcttttgg caaaagtgta ttgcccaaat cgatgatagt atcaccagaa atgatggcaa
     4261 tgttgatatc atcccattca tagacgtcgt ttccaatacg ttggttacca aataattgct
     4321 gtcttttacg ctcattatta tgtgttttta attgctctgt ttggaccatc atgatctgtt
     4381 tttttcgcca aaaagcattt tttgtcaaat ctattcctga aatctctaca cctttcagcc
     4441 cgataaataa aacggccaat acaaccatca tccataaagc aggactgttg actaagctaa
     4501 aaaaaatgac caagctccct aagatcaatt gaaaattttg aaatttagta cgaggatatt
     4561 tgcgcatagc tagatatata ttgaaaatac cgaatattac taaaagcaaa agtccagtat
     4621 tgtttacgat ttgccaaaca gcaaataaca gcagcagtgc ttcgactacc acaaaaaaac
     4681 gccaagaact attcatcgct ttttctccct cctgacacat tctcatttca tcatacctat
     4741 ttttttgact gttggctata ggactttaga tgtaagatcg ttcagtgaaa cctgcaatac
     4801 tcaaagagaa aagatctaga gtgcgtcatc agtaagatga actctctaga tctttcagtc
     4861 agactacgct tgttctactt tgacgatttt aactaacata tcgccacctg gtgtagcaat
     4921 ggttacttca tcatttttac gtttgccaat caatgcttgc gcgataggag aatcattgga
     4981 aatctttcca gaaaacgggt ctgcttcagc acttccgaca atcgtgtact cttcttcatc
     5041 tccatcaggc aactcgatga acgtaactgt tttaccgatc gatacctcat ctgcatctac
     5101 gccgtcatta tcgatgattt gtgcaaaacg gatcatattt tcaattgttg tgattcttcc
     5161 ttcaacaaat gcttgttcat ctttagctga ttcgtattcg gagttttcgg aaagatctcc
     5221 gaaaccgcga gcgattttga ttcgttcaat gatttctccg cgtttaactg tttttagttc
     5281 ttctaattct ttttctaatt tttctttacc ttctagagtc attggataaa ctttctctac
     5341 catgtgtaac gtctcctttt ttcgataaaa taccgcaaaa ggtaatcttt tgaggaatat
     5401 agtccaaaaa agattaccac gcttttctta aaatgtaaat gtttttctaa aaatgatcaa
     5461 tgactagccc ctgtttttct aagaattatt tacatatttt tgcactagtt ccatatgttc
     5521 ttcatacgtt ttagcgaaat aaacatttcc agtgctcgta tctgctacga aataataata
     5581 gtcattttct gctggttcta atactgcctt gattgcctct tcgcttggat tgtcaaaagg
     5641 accaggccca tagccggtat tggtatacaa attgtatggt gaatctacag ctgtatcttc
     5701 atacgtcacc aattctttat gttctcctaa tgcatataaa acagagatat ctgactgaag
     5761 tggcatattt gccttgattc ggttaaagaa gacttgtgca atatttttac gatcattttc
     5821 ttttacgcct tctttttcaa ctagagaagc caaagttaaa acttcttgta cagtcaaatt
     5881 tttctgtttg atagctgaat aatagttttg catgaccgta tttgttttgt tcaccatctc
     5941 aatcacaaga tccttaagcg aagtactcgt gtagtaatca taagtagctg ggaataagta
     6001 gccttccaaa cggtattttg tgttctcagc tttagaggca ctttccaaca attctgggaa
     6061 tttttgatac aactcgttaa agaaagtctc atcatttact aaatctaaaa attctttctt
     6121 gtctttacca gttaccttcg ctacccgctc agcaatctga tcgatgtcgt agccttctgg
     6181 aatggcaatt ttcccatctg caacttttgt tggctcagaa gtgccgcctt cttgcagctg
     6241 tttgccaatc tcgtcaagag tcatattagg cgctaactga taatagccag cttgaaagcc
     6301 agttaaattt ttaaattttg tataataatt gaaaacaatc ccgcttttaa taatattgtc
     6361 cttctccaaa atctcaccaa tctgcttgtt agaagagcca ctcgggatct ccacttggac
     6421 taattggtca tctgatttat ctaaaggctt caacccgcta tctacataac gatacacggt
     6481 aaatccaaga aatccgccaa taattaataa tgtaagagca atcactaaaa tgatcttcct
     6541 cacaatctta tcttcttttt tacgcagatt tctccgcttg tcgattatat ctgctgtagc
     6601 tgccttactg gcttcttttt tatctttact tgggtgttgt ttgtttcctg acaaaacaac
     6661 tcctccttac tatcatcttc gtaactctgt ttattataca tgaaatttct actgccgtga
     6721 attattttac caaatattat gtcaaaattg taagtggcaa atactctttt tgaggattac
     6781 aatgaaaaat agttaaaaat ggatagaaag gaattaacat gtcaaaagga aaacatcgaa
     6841 aaaaacaaaa aatttctatt tcttttcttg taattttatt attgtctgtc agcttctttt
     6901 caacaggcat cattatagga ggtcaattaa caaaaatacc tcattcccaa acttataaag
     6961 cggagccaac acaacttact tccaatttaa cgcccgatga gcagaggctt gctagcaaaa
     7021 ttgatcaatt actacaaaaa tcagattata tcggttcgat ttatgttcgc aaaaataatc
     7081 gcgtactatt agaaaaagga tatggatatg caaatctgcg cgtaaaagaa tcgaattcac
     7141 cttctattta ctatcaaatc ggttcgattc aaaaagcaat gactgcttta ctgatactaa
     7201 aacaaatcca agctggtaag ttaacttttg acacaaagtt agcagaattt tatcctcaga
     7261 ttcctggaag tcagcaaatc acaatcaaaa atatgcttta tatgcgctct ggtcttcatc
     7321 gaactgcttc tcccgacaaa cctatgtcgg atagtgaaat cattcagttc gcccttcatc
     7381 atttgaaact tactgattat gatacgtatc attatgaacc attgaattat acattgctta
     7441 cagggatatt gatcaaacta acgaatcagc cttatgaaac tcttctaaaa aaagaaatca
     7501 ttcgtccact ccatctagaa catacagatt tttatgacaa tgtaaaaaat tcgcctcaac
     7561 atgctgtatc ttaccagatg tctgcaactg acgattattc aaaagcattg atcgagcctg
     7621 aaaccgacat ccgaaatgaa ttaggtacag gaaacataag tatgtctgtt tatgacttga
     7681 acaaattctt taccagtgtt ctttctggcg gtatcatacc aaaagaacta cttttctcat
     7741 tgtggcaaaa taatggtgat aaacatcctt acagcggcgg tgtttacagt ggaaacgatt
     7801 atatccttgc tcaggggaat atcaatcgat tccatgcagt agtggcgatg aaaaaagaca
     7861 ctaaagatgc aatcgtcatg gaaagtaata tccaatcgga taagaacatc aaattgccgg
     7921 ccactgattt aagaaatcag atttatgaac tgatggaagg tgttcactta tcaaattaaa
     7981 ttttgacata atattagttg tcatctctgt atagtcaatt tagttagtac tctatctgaa
     8041 aagtagaaat aaattaacaa atattatctg tccttattat ttgttaattt atttcttatt
     8101 tta
//
LOCUS       DAIGUC010000086         7791 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.088, whole genome shotgun sequence.
ACCESSION   DAIGUC010000086 DAIGUC010000000
VERSION     DAIGUC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.088"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            636..1199
                     /locus_tag="NOB46_002575"
     CDS             636..1199
                     /locus_tag="NOB46_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1059476.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1478..1765)
                     /locus_tag="NOB46_002576"
     CDS             complement(1478..1765)
                     /locus_tag="NOB46_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1059477.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1755..2084)
                     /locus_tag="NOB46_002577"
     CDS             complement(1755..2084)
                     /locus_tag="NOB46_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1059478.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2389..2718
                     /locus_tag="NOB46_002578"
     CDS             2389..2718
                     /locus_tag="NOB46_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059479.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(3005..3490)
                     /gene="vanZ"
                     /locus_tag="NOB46_002579"
     CDS             complement(3005..3490)
                     /gene="vanZ"
                     /locus_tag="NOB46_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI1059480.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3643..4554)
                     /gene="vanY"
                     /locus_tag="NOB46_002580"
     CDS             complement(3643..4554)
                     /gene="vanY"
                     /locus_tag="NOB46_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCI1059481.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4982..5590)
                     /locus_tag="NOB46_002581"
     CDS             complement(4982..5590)
                     /locus_tag="NOB46_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI1059482.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5596..6627)
                     /gene="vanA"
                     /locus_tag="NOB46_002582"
     CDS             complement(5596..6627)
                     /gene="vanA"
                     /locus_tag="NOB46_002582"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI1059483.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6620..7588)
                     /locus_tag="NOB46_002583"
     CDS             complement(6620..7588)
                     /locus_tag="NOB46_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI1059484.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2376 a         1548 c         1297 g         2570 t
ORIGIN      
        1 cactctcctt gtatgcttta gcgggtatta caatttgagt gtaacataaa tggctttttt
       61 atttgtctcg cttaattata caaacggcga agttaaaact tttttagcag attttaaagt
      121 ttcgtcaaaa ctaatatatt ctggtagctg agcattcaaa tagctttcag acttcagaag
      181 aaaattacga gcatttttat agtccatctc taataaagtt attctttttt tatccaatac
      241 attcagctca attccttata atattctatt ccttagtatc tcaacattat ttactttata
      301 aaacgaataa attttgtagt tctaattcaa atattgcatg ttatatctaa tatgggagca
      361 ttttataatt ttcattgtga taaactcgtt attaacttta ggatacacta gttaggatta
      421 aattaggtat ctagaaattt acttaagatt tttttgttta tttcgtatac acactcgtat
      481 caaaaacaat cgattatgag acaaaatgaa atgacctctt ttattaaata aaagaggtca
      541 tattttgtat cataacttgt tgcattaact atgtatctat aactcccttt tatgatacaa
      601 tcaagccaga attaaagtac gaaaggaaga aaagcatgag tggatacatt tatggttatg
      661 cccgagtgag tacacgttca caagaactaa atcgtcaatt agacttactc aatgaacaaa
      721 attgtaatga aatcctaact gagaaaatga cgggaaccaa agcggttcgt ccccaactaa
      781 atcgtttaaa agataaaatt cgtccgggag atacggtaat tgtagaaagt ttttctcgat
      841 tgggtcgtag tacaaaggat ttgattgacc ttgttaccta ttttgaagaa caccatgtta
      901 agctggtgag cttgaaagaa aacttcgata ccagcacgcc tcacggacgc ttaatgatga
      961 ctgtcttcca agcatttagt cagttcgaac gtgatttaat tgttgaacgt accaaagaag
     1021 gtttgaaaag tgcacgtgcg agaggtcgta aaggtggccg tccacgagtg aaccagaaag
     1081 atgttgatcg agcagtaaaa ttgtataaaa gtcaggttta tagcgtaaaa gaaattacgg
     1141 aaatgactgg tattagcaag gcaacactct accgctactt aaaagacaat agggaataat
     1201 ctattttaat ctttaggaat ctataatatt tatgggagaa ttagagtgat ttttttatta
     1261 ttactaaaaa acaatataaa ataacgcatt ttaagccctc tttgtgcata aggatgaagc
     1321 ttttaatttg aaagaggctt aaaatgcgtt ttaatttttt ctatttttca taaatatata
     1381 ggttagtggt ttaaaattat agggtattac aactctcagc tgttaaaaat tatcttttaa
     1441 agtgtcgtct atcctctcaa gttgaaacat tgggttctta cctaatcttt tttaattgtt
     1501 cataaaaatt ttcatgcgtt ccacatagta agataggtat cactgcatta tctttaattt
     1561 catatgcaac gcgatatgtc gtacctgcat acttgaatcc aatagcccaa attcctgata
     1621 aatcacccgt tttttgttct cccgaatgag gacgaactgc tatctcatca taaattatcg
     1681 ttaaaaattg ttcttttaat gttttctctt ttaatttttt tagatacttt attacgtgtt
     1741 tagaaggtag aatctcataa gccaatttct gctgccaact cctcttttgt catcggttta
     1801 gaatttgcaa cagtatcttc agcaatagat ttaaatgcag aagttaacgc attttttcta
     1861 tttctaaatt cttttaagat ctcttgtttg ctataacctt ctgaaagaat atcagccaaa
     1921 atatcttcac taaaatcaaa aaattctttt ttaggctcta caaactcata aaggatacca
     1981 ttctctacaa gcttagcttc tacttcaaca ccattgggca catcgaattc tttagggacc
     2041 gttaacataa tagaatttcc ttgttttctt gtttttgtaa tcatattatt tcctccatta
     2101 ttttacattt cgtaattact tagtaattac attgtacgct atttttagta gaaatacaaa
     2161 ataataaaac tcctttagaa caattttcaa aggagtttta tttgattagg aaattatgta
     2221 gaataataat atgtttttaa cttggaatca aaaacgcact tgcaagtaag tttacttcaa
     2281 tacatgaaat tgcttataat agtgtattgg aattaaggta gattgacaaa agagtgatca
     2341 aataggtata cttcattcaa ataatcgttt gaatgtgagg tgagatgaat gaaaaaagtt
     2401 tgccaagtga ctgtcgtaca taaagaaaaa gtaaatggaa taaaaaataa attggatcaa
     2461 aaagattttt caaacttact tgtgttaggg aaatgtttca gcgatttttc tagaattaaa
     2521 attttctatg ctttagaaac ctataaggaa atgtgcgtct gtgatttagc agaaatactt
     2581 actgctagtg tcgctacaac gtcacaccat ttacgttttt taaaaaaaca tggaatggca
     2641 aaatcacgtc aagatggaaa agtagtttat tactctttag cgaatgaaga catcctttcc
     2701 gctattcgtg ttttttaaag ttatcagaaa atctatctat gaaatcttag tttgggggta
     2761 ccgtcaggaa aatgcggatt tacaacgtta aggaaattta ttaaagagac caattcctca
     2821 gcactaaaat tgataattgg gctttctttg ttactatagt gttaggtaag ctttttactt
     2881 tatcaccggt tttcccctca cttcacacct acgggcgagt ttccccacat cccgttttcc
     2941 atctaatcca attcattcaa tatctttatg tgtatgaaag atcagattgc ttgatttaga
     3001 catcttacac gtaatttatt cttaaatggg tacggtaaac gagcaataat acgagcaaaa
     3061 gtatacctac aaaaataata actctgtcta attttttttg attcatatgc ttattgctta
     3121 aaccatataa tttcagtcca agaaagcctc caacagtatt tgtaattaca tctgttatgt
     3181 ctgtcgctcc aatagcgaag ataaattgaa ttatttcaaa agtaagactt aaaaccagta
     3241 caaaagcaaa cttaggtaaa aatccgattt ctttaaaatt gacattcaaa agcaagccaa
     3301 atggaataaa gattataaca ttatctatca tctctctgaa attcccagta gcagtaaatg
     3361 gagtcaagtt aagacttctt tgatgataat taaatactga taaaatattg tattgtaatt
     3421 tgaataacac taaccagatt agtgtcacta aatataaagc tagcaatcct ctagataata
     3481 tttttcccaa tataatttcc tctaattctt ttgtttaagt tgtatcatta gtatagcaat
     3541 gtcctagtta acgtgggttt taaattaaaa agctaacgtt accccaaaag tgctagtaca
     3601 ataatgctgt tcattaattt cgttggtttc attccgccat ccttacctcc ttgaattagt
     3661 atgtgttgat ccgggaaaca ctgtcacaat tacaccgtct atattgtttc ctgatatctc
     3721 ataacgaaga ttagtcggca catgaatggt ggtattttta gtaacaggat aataaaagat
     3781 ctcatatttt tccccattta cactaacaga aatggttttt tcttctttta ggtaatccat
     3841 atattcctcg agaacgaaat tcttttcttt cataatcgca ctatgtggta aaccaacata
     3901 gcgaatatgc catagttcat attgaattcc tgttaactct gttttgtcct ctggataacg
     3961 taaaatgaac ccgtatttcc aagcattttc ttctatccac tttccttcag gggctcgttc
     4021 cattttcgtc aagcttgatc ctacatctag tgataaacct gaattatgct cactataacc
     4081 tgctggtaag gcatactcag cccccatttc ttggtaaagc acactttgct catcaaagtc
     4141 tcgatagcca ctattaataa taaaatgact aacgccaccc tttacagcat cattgaccat
     4201 ctctgaaaat ttttgtgcta tttcttttga catataaata ttactatcaa gcaacccgta
     4261 tccatttatt aattcgtcat gtttagataa attcacgata tctgacttca cactttcttg
     4321 gcgaacagga tatttactat tgattaatag cagatttcct tgataaacct gttcttctgt
     4381 aattgttttc tcttgggtat tttcagaagt cccactattt tctaaatgtt ctttgggatt
     4441 ttgatcataa ttttgaaatt cgactttttc ctgagaaaac agtgcttcat taacgtagtc
     4501 ataacctaag tatattaaga ataacaataa caataaaaaa aacaacttct tcattttcag
     4561 tctcctcctt aactatatag ttggaagtat gaaatatttc tagaatcttc cccttaaacg
     4621 gcacaatctc gtttgagatt gtgccgtttt gccccgtaaa ttacagtcaa ttatttcgcc
     4681 ctactggatt tactattatc accaatgtag atgaattttc ataagtgata cccatgctga
     4741 atttaacgag gctgaactgc ctgttgacaa tgggcggtgt gaaataccac ccctctatgc
     4801 gatcagtctt attatcaggc tatcttgccg cagcgcacgc agataatgac cgcaatatcg
     4861 ctctgcctta catcttcaat actatctact atatataaat tccctaagaa ccagttacat
     4921 acgtcgggtt tcctgccgaa agagttagct tatatagttt gtccgtgcaa cggttaaaag
     4981 tttatttaac ggggaaatca aaatagctat tggggtatgg ttcgtctctt aatacatagt
     5041 gccaccattc gaggctatat gcttcaaacc cactgttttc catgatggag cgcaaacgtc
     5101 tgcgattttg cgcttcattg catgatattc catttgccgc atgatgagag cgttcatcca
     5161 taaaatcaaa tcggctcccc attggtacaa gctcacccgt gtctaatcga taaagcgtaa
     5221 gatcaatggc actgccgcgg ctatggcttg attttgaagc cacgtatcct tttgaaatca
     5281 tctcagttcg gtcaatattg ggataataac tttcctttgt caggttattt tccggctgtg
     5341 cagcccattg cataaaacag tttacagcac gattaggacg gtaaccgtcc catagaagca
     5401 atccgtaccc ttgggtagca gccagttctt ttgccttcaa aagcgattca gccaactcgt
     5461 atgtccctac aatgcgattt acttcataac cgtcaaccgg ttttccggtg aaattatccc
     5521 aagtggcata tttagcgtcc caacgaacac cgtgtactat ttcatctaaa aaagtaaatc
     5581 ctatttccat gcttatcacc cctttaacgc taatacgatc aagcggtcaa tcagttcggg
     5641 aagtgcaata cctgcagcgg ccatcatacg gggataacga ctgtatgacg tgaaaccggg
     5701 cagagtattg acttcgttca gtacaatgcg gccgttatct tgtaaaaaca tatccacacg
     5761 ggctagacct ctacagccga gcgctttata tatttttttt gccgtttcct gtatccgtcc
     5821 tcgctcctct gctgaaaggt ctgcgggaac ggttataact gcgttttcag agcctttttc
     5881 cggctcgact tcctgatgaa tacgaaagat tccgtactgc agcctgattt ggtccacctc
     5941 gccaacagct aacgcggcac tgtttcccaa taccgcacaa ccgacctcac agcccgaaac
     6001 agcctgctca attaagattt tgctgtcata ttgtcttgcc gattcaattg cgtagtccaa
     6061 ttcgtccgcg ctattgactt ttttcacacc gaaggatgag cctgaacgcg ccggcttaac
     6121 aaaaacagga taggtaaacg tagctgccac cggcctatca tctttattaa taacccaaaa
     6181 ggcgggagta gctatcccag catttttcgc aacgatgtat gtcaacgatt tgtccataca
     6241 aattgctgag ctttgaatat cgcagcctac aaaagggata ccggacaatt caaacagacc
     6301 ttgtatggat ccatcttcac ctgacttgcc atgcaaagct gaaaatgcta catcaacatg
     6361 gttgatttca tattcatggt tctttttaac aagtaatccg tgcatttttt tatccggcga
     6421 gagtacagct gaatagcaat tgtcgttttc ccattccgcg caaggttttt cgcacatttt
     6481 ccatacacca gatttcgtaa ttccaatgta taacggctcg tatttttctt tattaatgtt
     6541 agcggctatc tctattgcag attttaccga tacgtcatgc tcctctgagc aacccccaaa
     6601 cagtattgca acttttattc tattcatgct cctgtctcct ttcaaaatcc aaacagtttt
     6661 taatggtttt ttcaacggta tcacgcaacg cttgctcggt ataataggcc gtatgcggtg
     6721 tgattatcac gttaggcatt ctttgaagtt taagtaaaaa ttgattatca attggttttt
     6781 gggtgcaatc agagtagaaa aactcttcct ctccttccaa tacatccaat gcggcaccgc
     6841 ccagtttccc gttttctaat gctttaacca actcataggt atctacaagt ggaccgcgcc
     6901 cagtattgat aagaaatgct ccttgcttca ttctctgtat ttgttcgtgg ctgataatat
     6961 agtgcgtatc cgtattgagc ggcacatgaa gcgtaacgat atcgctattt tgcagcaact
     7021 catcaaacgg tacatagttt acctctatac ttcggctgcg actataagcc aacactttac
     7081 atccaaatcc tcgcagccgc tcaataaccg ctttgcctat ctggcccgtt cccaccacac
     7141 caactgtcat gtcgctgagt accttgccac ggtcgctgtc caacctgaaa tcatgttttt
     7201 ccacagagcg cacaatcgat tttacgttgc gtactgccat aagaattagc atcatagtat
     7261 aatcggcaac gctatccggc gagtacgcca cattgtcgac agtgatgccc attctcttag
     7321 cagcagttgt atctatatga ttgcagccga tgcttcgggt agaaatatat ttcacaccgg
     7381 ctctcttcag cgcaagaaga atagaggcgg aaatctctga tttatgtccc acactgatac
     7441 attgattgaa aggcgcggat ttggcgttgg attccgacac gttggcgtta attatcgttg
     7501 ccataacgcc aaagcgaggc gaaagagcat ggaatgcatc tgcctcatcc tgctcacatc
     7561 cataaacagt aatgccgatg ttattcataa ttaagaccaa ccctttctgt gaaaggcacc
     7621 aaataaaacg gggatgccaa tggtaatctt gtcaaatctt tctctgaaga acgaaaacgg
     7681 ctcgttctta cggtattaag tctaccgtgt aagaacgagc cgtttcttaa tattaaattg
     7741 ttaatttcct aagaaaaagt aaagataacc ttgagatttt cctaaaaaat t
//
LOCUS       DAIGUC010000087         7600 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.090, whole genome shotgun sequence.
ACCESSION   DAIGUC010000087 DAIGUC010000000
VERSION     DAIGUC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.090"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(943..1356)
                     /locus_tag="NOB46_002584"
     CDS             complement(943..1356)
                     /locus_tag="NOB46_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HCI1059485.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="NOB46_002585"
     CDS             complement(1812..2297)
                     /locus_tag="NOB46_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059486.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="NOB46_002586"
     CDS             complement(2436..2651)
                     /locus_tag="NOB46_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCI1059487.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="NOB46_002587"
     CDS             2875..3675
                     /locus_tag="NOB46_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI1059488.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="NOB46_002588"
     CDS             3694..5562
                     /locus_tag="NOB46_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI1059489.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPTNRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="NOB46_002589"
     CDS             5555..6046
                     /locus_tag="NOB46_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCI1059490.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="NOB46_002590"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="NOB46_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCI1059491.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="NOB46_002591"
     CDS             6606..>7600
                     /locus_tag="NOB46_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCI1059492.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1214 c         1443 g         2236 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccaccaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAIGUC010000088         7581 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.091, whole genome shotgun sequence.
ACCESSION   DAIGUC010000088 DAIGUC010000000
VERSION     DAIGUC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.091"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..662)
                     /locus_tag="NOB46_002592"
     CDS             complement(<1..662)
                     /locus_tag="NOB46_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI1059493.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HD"
     gene            complement(1099..1668)
                     /locus_tag="NOB46_002593"
     CDS             complement(1099..1668)
                     /locus_tag="NOB46_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1059494.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1742..2065)
                     /locus_tag="NOB46_002594"
     CDS             complement(1742..2065)
                     /locus_tag="NOB46_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059495.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2219..3031)
                     /locus_tag="NOB46_002595"
     CDS             complement(2219..3031)
                     /locus_tag="NOB46_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059496.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3385..4233
                     /locus_tag="NOB46_002596"
     CDS             3385..4233
                     /locus_tag="NOB46_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCI1059497.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4378..5319
                     /locus_tag="NOB46_002597"
     CDS             4378..5319
                     /locus_tag="NOB46_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HCI1059498.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5309..7480
                     /locus_tag="NOB46_002598"
                     /pseudo
     CDS             5309..7480
                     /locus_tag="NOB46_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2260 a         1507 c         1359 g         2455 t
ORIGIN      
        1 ttgtcatgaa aatcttgtgc tccaccctta gtatttcctt ctggatcgtt tgtcgcacgc
       61 atcatgacgt atactttctt attagggaaa tcacgcatat tgaaagatac atgatagcca
      121 acatttccta aagtattata agcttgattt acgtctggtc tataaatccc atcagctctt
      181 actctagcta gttcttttcc agtattgtag tccataatga aaatatactc gtatttataa
      241 ttagcaatgt gccatccagc tacatgcaag tttgcgtttt cgatttctcc gaactgatca
      301 atgtgggcgt aatttgttcc atctgtcagc gtagaatttg cagcacctgc tcgagttgga
      361 tcaattactg gtttatcctc cgaagtagtt ggattatcat ccgtaaaacc atgagccaaa
      421 tcataggcta gtttttcttt acttacacct atttcagaaa gataaccgta aggatctgta
      481 tgatcgcccc aaatattttg tgttacccat aaatgcgatt tgattcctgg ttggttataa
      541 ggagtgtcta atgttaatgg aataccatat ttcattgctg aatctcttgc caattcaacg
      601 tatactttat agttcttttc aaaagtttct ttatcatgtg tgtgttgtaa ctcgatttgc
      661 acaggacttt tggctcacga ggttgtccta ctctacatct tgctgataga tatgctgaaa
      721 ggaaaacacc aacattatgt tttgcttttt cagctagaac gagacaagca ggaatacctt
      781 tagaagatat caaaggtttt ttaggtcata aagatgtttc cactacacaa gtctatgccc
      841 atatttctcc cgaagtgaaa aaaagatcaa tgaatcaact agaaaactat atagaagagc
      901 aaataaaaaa gcactcaaat tgagtgcttt tttaagctca ctatcactaa aactatcact
      961 aattttattt ataagcgaac atgtttctat cactgatttt ttaaatctag cgaaaaaccc
     1021 ttatcttaaa ggcgttcgtt caattctttg gcaaggtctt caaagcctgg cttgcctaga
     1081 agtgcgaaca tggttttctt atagctcatg tagaaaaatt ttcttgatga tgattttatc
     1141 catcaattga gattgactgt tttgctctcc tatgatttca gctatgattg tccgattttg
     1201 cggttttctt cttaactggt agttgatttt cccagtttcc atcaactcgc taagcatatc
     1261 cacgactccg ccaaatccgg tctttttcgt aataaaacct agtgctacca ttcgttcatc
     1321 tagatttttt gctgtaatcg tcacaccagt aatgagcgag tgctgtaatg tttgggccag
     1381 ctcttccatc ccttcagcat tggatacgac ggaagctgtt ttgttaatag gttcttcgtt
     1441 tatttctttt ggttctttcc tctccacttt cactgtttga cgaaggacat ctagttcttg
     1501 caagagcgtt tcgtattgtt cttgggtcag catcacgcca gctacttttt cacgattaaa
     1561 tatatatacg ccagttcccg cgtctcgcgc ttgagcaaat acatccatcg gcgatcgttt
     1621 cacttctgtg atcgaagatg tgggaacttc taatttcttt aattccaatg gatttcctcc
     1681 tttactaatc gctttttatt atagcacaga ctgacttgtt ttgatctttt ttccaaaggt
     1741 tttatcggtt tttgcctaac cagtaattga tatcggtaag aagtctttcg ataccaaatg
     1801 aaggatggta cagatacgtt ttttgatctt cgttatggtc tagtggaaaa aaatgatcga
     1861 tgatcactag atctgcatac cgaggcggct tatttcgagt acatacatgt atagagatcc
     1921 gttttcgatg tcttagcgtt ttgttcagta ccccagcaag tcttcttgct tcttggtgtt
     1981 catagcgaaa aaaaaagacg attttcactt caggagggtg gacatctaaa taccctcgtt
     2041 cctggagtgt tttcagtaaa agcatccccc actctactgc ggggtgtgca agtgcttgtt
     2101 ggatcgctag ccgaaattga tatagtttat ctttggaatt gggaaatttt tctaatgttt
     2161 cctgataata acgaacttct tctatcagcc ggtcatggat accaattacg taacgaagtc
     2221 attcttggta aagtactttt gtcagctttg atttgctttc gctctcaaat tcgctattca
     2281 gccaaaacag cgaatcaagc ttttcagtca caatcgtcaa tttccgatag tcttgtgtct
     2341 cttctatccg tttccaccgc ttttcagtaa tctggttaca gctcaagcgc aaaattgcta
     2401 gataattttt ttcttttatt ggcaaaatct gctcctctct aaatagcaat tcaggaaaca
     2461 attcaaagaa tagtgttcga ctgtctccta aaatctcgat ttctgccgga tcctttcttt
     2521 gcttcaataa ttggatgaac atctcagaaa aggactgctc tccatcatct gcaaaaaaat
     2581 gcggaaaatc tttcaaaaag caaaacagca gatatcttac ttttctttct gaaccaaaga
     2641 tctgtgcttt tttataagaa aaagaaaggt ggtactcgcc aaaccacttt ctcaatcgct
     2701 cttgcgtaga acgatcgtac ttctgctcgt aaggttcatt caatagcaga tttttcagta
     2761 aacaaaacgg gggtgattgg atcagaaaaa caaacaagag ataaggttcg ctatatcctt
     2821 gatcataaac taactgaacg gttttcttat gaagaatcag ctgaatggga cagtcgcttt
     2881 ccgccaaacg tttcagatgc cgatccactg ttttaacatc gattttcagt tcttcagcta
     2941 aatcagcttt tcgccagatc aaatctttca ttagattgat tagtgaaaat aaattctgtg
     3001 cattttttga taatagtttt tgccatctca tcgatcattt ctcacctgat ttctaaacat
     3061 attgtttgat caaaatgggt tcactcctaa aaagataaaa aactcccttt ctatttattt
     3121 aaatacgcaa atcttcctca ttatttttta ttttactcaa tttaatcgta ttctcatttc
     3181 aaaacgaatg tactttaaaa aaacataata agatcacttt gcttgtagga tgtattccct
     3241 tccattacaa tgaaataaat agcgatttta tgagaaggtg atgtgaaaat ggaagaaaaa
     3301 atagaagaat ccaaacaaaa aatcgatcag ttgatataag aattagaaaa agcggtcatc
     3361 ggcaaacgtt caactatcca attgatgatc gtggccctat tagcaggtgg tcatgtctta
     3421 ttcgaagata ttcccggtgt aggtaaaacg ttactggtca aagcactagc aaaagctgta
     3481 cagggaacct tcagcagagt ccaatgtact cctgatctgc tgcctagtga tattcttggt
     3541 ttttccgtat acaattcaca atcaaaagag tttgaatttc gtccgggacc gatctttacc
     3601 acgatcttgt tagcagatga gatcaatcgt acgactcctc gtactcagtc agcactttta
     3661 gaagcaatgg ccgagaatca tgcaacgatc gacaacaata cataccctct agacaatcat
     3721 ttttttgtct tagctacgca aaatccaatc gagtacgaag gaacatatcc tttgccggaa
     3781 gcacagctcg atcgtttttt attccgacta caaatcggtt atccttcttt tgatgacgaa
     3841 cttttgctac ttttggataa attcgaaaaa gtgttggata acttaaatga agtattgaac
     3901 agttatgaaa tagaagaaat aaaaacaaat gtggcgaatg tctttgtcag tcccgaagtg
     3961 gcatcttatg ccttgcagtt agtgtcagca acaagaagtc atgctgccat ccagcttggc
     4021 atcagtccac gaggaagcct ttcctttatt caggcagcaa aagcttatgc tttaatccat
     4081 gggagaaatt acgtcacgcc caaagatttg caggatttag ttccttacgt gttttcccat
     4141 cgcctgattt tttacgatcg ttcattgaag gaagacgaaa agaaacaaat cattcatact
     4201 cttgttgcac aaattcctat tcctgtgagg tagattgagg tagacaatgg aaaaaatcaa
     4261 agattatttc attaattttg tgttatttct ggtatatttc atcattgtgc tttttgctct
     4321 tgtattcaac aattctttag gctggttctt gttggccttt tttactcttt atgtatcatg
     4381 gagcttgatt tcattaagca gctttctaaa gaaactttcg gttacttgta cattgcagcc
     4441 actcgtttat cgcaaaaaaa gtatgcaggt tattttttcc atagcaaaaa agagaacttt
     4501 ttctttacct ctccctcgtt tacaaatcgg cttcccagca atctttgcag aaaaaaacaa
     4561 gagattttga ttcttacaaa taaaccgcaa gaagtccaat tgctttggca gccaaaagaa
     4621 agaggatgcc atgaaacatt aactgtcatt tttacagcct atgatagtct aggacttttc
     4681 agaaaaagtg caaaaagaga gatctctttt cctgtgactg ttctgcctgc tttttgtaag
     4741 attcaagcag aaaaattaca gagagttctg gaaaaaaaac agcagctgaa cgcgtaccaa
     4801 agaggtcttg attttcggga acatcgcgct tatcgtccag gtgattcttt caaccgaatc
     4861 gattggaaat tgtctgctca tactcaagag tggttatacc gtgaatacga ttatcaagaa
     4921 gaagaatgtt ctcctctttt ttgcttttgg ggttcgccca gtccaaaatt tgaacctctg
     4981 ctagacttgt atttttcttt atggcatttg agaaaagaaa agcagccgga acttctgata
     5041 ttaggcaacc gcgcctttca tggcaaagac cccggtcata cctattttgc ttctttggaa
     5101 gctggcgatg agaaaacttt tttcgcacac ttgaaaaaat atgcaaaaaa acaaatcgtc
     5161 ctctttgttc ctgagaattc tcctgaagtc tcagaagcta ttgaaacatt gtcaaaagat
     5221 cgaacggttt atcttgttta tttcgtagaa aaacaactca tggtccaaga aaaagacaag
     5281 atatgttcat tgccaggagg tgaatggatt gacgattaaa cgggaaaaat ggctgcgtgg
     5341 cgtttactcc tttgtgatac taagtgtagg tgctccgata tttgtagtag ctaatcaatt
     5401 gcaaaacagc taccttctta tcctaactat tggtgtccta tgccttattg tctgctgtat
     5461 tcctaaaaaa tgggtacgtt tgctgctttc tttgccagta atgataggtt gtttgttttt
     5521 atattttcct tcgaagacat tttccatatt atggatctta cagttttttt cgtcagttac
     5581 agaggaattc ttccatctat cccaaggtaa actttattat ttgccagaaa agacagcttt
     5641 ttttctcata atgttgctga tctatttatt tattacattg accgtggatt acgactattg
     5701 gtacgcaccc tttctttctt tgatggctta cttcatgatg cttaccgttt ttcggaaaaa
     5761 agatttactg tacgaaatga ttgcggtagt aactgttttg ttcgtgtatc tggcagcaag
     5821 gcaatttttc tccatccggt tgttgtcgag aaacactcga ttccagtcat tgactacagt
     5881 tctgcttatt tgtttcttaa cttttagcgc tatcttgcct ttatatcttc cgaaagtaca
     5941 ccaatctctc gaggaaacga gtgaaccgat ccgagaatat cttaatgatg aagggcttta
     6001 tgacacactc catgagtatc aattaaccgg aagtgcaaga acaggcttca gtgagaatga
     6061 tgaacagctt ggtggacctt tatatgataa tggcgaagtt gtttttacag cgaaccaaaa
     6121 aggaaatggc tattggaaga tcgaaaataa aaatcattac accggttctg gatgaataga
     6181 agatcaggac gcacccatcc aaccaatcca agaattccct gttgacatca cgagctacca
     6241 aaccgttata gaagacaaag aaaacattac attgacccta aaaaaacaag ctttcttacc
     6301 ttatccttat ggaaatacta ccttgactga tttttcatta gctagtggac aaacgcttta
     6361 ctatttgcct gaaagccagc gattcattcc tgtcccgaat gaatcgacac gttctgcaac
     6421 tttacaaaca gaaaggttag tttttacgag agaagaatta aaaagcagtc agttaaaagc
     6481 tgatgattta gaaaatcagc agacaaatct tcaattgcca aaaagtttgc ctaaacgtat
     6541 tgaggacttg gcggtcgaat tgaccaaaaa tgaagcaact ttaattcgta aagtcgaagc
     6601 tgtctaacag tatttaaaaa caagcggaaa tttccgctat tccaaaacgg ataccgggca
     6661 tactccaaaa gaacacgatt atgtggatta tttcctcttt gattcaaaag tcggctattg
     6721 tgacaacttt tcaacttcta tggtcgtcct tcttcgaaca cttggtatcc cagctcgctg
     6781 gacaaaaggt tttacaaatg ggctcagaac aggcacagat aatcaaggga atgaggaata
     6841 cagcattctc aatagtcatg ctcattcttg gccagaggta tactttcctg gatttggctg
     6901 gcttccattt gaaccaaccc cttcatttgc caatccaatg ggttcacaac cagttgctga
     6961 aacaaccgaa accgtccagc ctgctatcga acaaccaaat gaaagcgaaa atatggcaga
     7021 aactatttcc agtgagagat ctgaggtcat tccatcagaa gaaacaacac tcacaccagc
     7081 ttataaaatc gtcttattca gccttggagt gtgtttatcc gtcttgttgt tctttctatt
     7141 gttattcaga aaatctctgc gctggacaag ttatcttatc tatcttcatt tttttgcttc
     7201 tactaatacg attgcatatc aaaaacttct taaccctttg gaaacattgg taccgcgcaa
     7261 acccgcagaa tctttgcagg aatatagcct gcgaatagaa caagaattca agctagatct
     7321 gcgtttcatt cgattaacta ctcaatatga agcagaaata tatggacgac aagcagatcc
     7381 ggtaaaattc gataaaaaaa cctatttaga aataacgcat ataataagaa aaacggtata
     7441 caaaaaaatt ctgacaaaag ggagccgctt caaaaaataa gataaaattt ctggagaatc
     7501 tacttctcga atgccgagaa ccagctgatt gagtatcgat tactcgaaaa aaaggttgtg
     7561 acacgttttt tgtcacaacc t
//
LOCUS       DAIGUC010000089         7497 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.092, whole genome shotgun sequence.
ACCESSION   DAIGUC010000089 DAIGUC010000000
VERSION     DAIGUC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.092"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..115)
                     /locus_tag="NOB46_002599"
     CDS             complement(<1..115)
                     /locus_tag="NOB46_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI1059499.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="NOB46_002600"
     CDS             246..698
                     /locus_tag="NOB46_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059500.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="NOB46_002601"
     CDS             712..1401
                     /locus_tag="NOB46_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059501.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPILPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="NOB46_002602"
     CDS             1526..3877
                     /locus_tag="NOB46_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HCI1059502.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="NOB46_002603"
     CDS             3957..4352
                     /locus_tag="NOB46_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059503.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="NOB46_002604"
     CDS             4677..5294
                     /locus_tag="NOB46_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1059504.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="NOB46_002605"
     CDS             5335..5634
                     /locus_tag="NOB46_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HCI1059505.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="NOB46_002606"
     CDS             5668..5835
                     /locus_tag="NOB46_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1059506.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6485)
                     /locus_tag="NOB46_002607"
     CDS             complement(5880..6485)
                     /locus_tag="NOB46_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1059507.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(6745..7425)
                     /locus_tag="NOB46_002608"
     CDS             complement(6745..7425)
                     /locus_tag="NOB46_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HCI1059508.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
BASE COUNT         2527 a         1101 c         1444 g         2425 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattttgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttccatc
     6421 attgccaatt gtcgatccaa attttgatct tgtgaagata ctcgaatata gccaattttt
     6481 cccataaaaa actccttttt aaaagtgata taatttacat gtaaaattta cttgtagttt
     6541 tactgctatc atagcatttt taaaaataaa ttttatgtag acttaaaatt tacttcatgg
     6601 agggtttaaa tggatgaaat caaaagtaac aaaaaagcat ttggcattta tttaggagaa
     6661 cctagtacag aacaattaaa ccaatttttt ggttctgttg cgaagtttga aaatcaaacg
     6721 cgccctctct gaactccaaa tatcttaggc tgttattccc attaatacct tgatttcagt
     6781 agacaccgaa aagccgaaga gcgttccatt tcttcggttc tttttatata ttcctcgaat
     6841 ggtctccatg cccttaatcg tggaagaggc tgtacggaga ctttgataaa atttatttcg
     6901 tcgtttaata ggtcgatggt cttgttctat taaattgtta agatacttca cagttcggtg
     6961 ctctgtctta gtatataaac ccacactctg taactttcta aaggcggagc caagagaagg
     7021 tgctttatcg gtcacaattg ctttcggctc accaaactgt ttatggagtc gttttaagaa
     7081 agcataggct gcttgcgtat cccgtttctt tcgtaaccag atatctaagg ttaagccgtc
     7141 cgcatcaatt gcacgataaa gataatgcca acgtccctta attttgatat aggtttcgtc
     7201 cattttccat gaatagaagg attgtctatt tttcttcttc caaagataat agaggacttt
     7261 gctgtactct tgcacccaac gataaatcgt agtatgacaa acatttattc cacgatcata
     7321 taacaattcc tgaacttcac gatagcttag attgtaacgc aggtagtaac caacagcgac
     7381 aataatgacg tcttttttga attgtttgcc tttaaaatga ttcattactc tgtcctctct
     7441 gtcttttttc tcaattttac actaaaatag attttttgga aaactttgca acagaac
//
LOCUS       DAIGUC010000090         7337 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.093, whole genome shotgun sequence.
ACCESSION   DAIGUC010000090 DAIGUC010000000
VERSION     DAIGUC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.093"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(482..907)
                     /locus_tag="NOB46_002609"
     CDS             complement(482..907)
                     /locus_tag="NOB46_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059509.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1281..2252
                     /locus_tag="NOB46_002610"
     CDS             1281..2252
                     /locus_tag="NOB46_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1059510.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2284..3681
                     /locus_tag="NOB46_002611"
     CDS             2284..3681
                     /locus_tag="NOB46_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI1059511.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3840..4463
                     /locus_tag="NOB46_002612"
     CDS             3840..4463
                     /locus_tag="NOB46_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059512.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            5212..7305
                     /locus_tag="NOB46_002613"
     CDS             5212..7305
                     /locus_tag="NOB46_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI1059513.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         2503 a         1230 c         1489 g         2115 t
ORIGIN      
        1 aaaaccaaac gacgggaaag aaaaattact acgtgatgta gaataagcct ttctatcgtt
       61 tggttatttt atattcaaat atttgaaata aataaatctt tactctttga tttgtaaact
      121 gaaatgatcc actgtttgtt ttactgatga agcttgatca aaggaagaag ctgagtttga
      181 agttcataaa aatcagccat agtgagtttt gcttggattt gtttatcttc ttctactttt
      241 tacataattt tgaacaggat aagattcaaa tgttttaaat gaatctttga ctagtttgtg
      301 acagttgtcg catatgctca agcttccttg gtcattaaat tctgtatgga tatttttgtt
      361 gttattacat gtacaataat caggactatc gatcatccat ttcgtctcct ttacaatcat
      421 cttgcttctt tactatagca gaaaagaagg ggagaaacaa aagaagatcc aacagacggc
      481 actatagact gtagatgttg ccatcctcat ccttcaaacg gtaattaccg atttttgtaa
      541 atatgactgt tgtttctttt ttattttctt ttcctgaaat aatatattcg tcatctttgg
      601 tagtgatctt gatatctgtc agcactgttt tttcttcaga tgattcagaa gaatcagttc
      661 cttgtgtctg atacgtgcgt gtccattcca tttttttatc tgtaaatgtc aactgtcccg
      721 cggataaatc catatcttta cgtactttta gcgtatatac actgttggtg gtatctgctt
      781 tttccgcttt taagacagaa gaatcggttg tttcgtccga ggattggtca gagccgccaa
      841 acaaatcaca gccagtcaat gtcaaaagtc ccgcagacaa aataaatagt acgattaatt
      901 tcttcaaaat acttccccca tttgatagga taaagaaatt ataccattgg aatgtaaaac
      961 ttcaaacgga tggaagagaa aaacgcacaa aacacccaca aatagagtaa attttagaat
     1021 aaaattttaa aaaggcaaaa aatccgccac tttcagaaag cgttttaaaa aagtgttgca
     1081 atcttttaaa aaaatgctat attaaaaatg aaccggttca aatacttgtt taagtataat
     1141 taatagtgag aggaagttgc tctactgaag actttagtta tatggatatt gatgacaagc
     1201 aacactatgc aaagaatgcg gtcatcataa tcgaacaaca agaaagagaa atcaaatgta
     1261 actggcagga gtgagaatgt atggcatcga tccgtgatgt ggctaagatg gctggtgttt
     1321 cagtgggaac agtttcccgt tacttgaatg gtcagcaact gaaggaaaag aacatgaaaa
     1381 aaatagcaga agcgatttca gcgttggact ataaagaaaa catcattgct aaagggttga
     1441 agaataatcg aagcttctct attggacttt tgataaacgg gatttccagc cgttttgggt
     1501 cggaagttgt ctcagggatc gaaagagtag ctgaagaaaa tgggtatagc ttattattaa
     1561 gcgggtttgc cgatcagcca gaaaaaattg aacaaaaaat tgaatacctg atgaagcatg
     1621 tgatcgatgg gctgattgtc ttcttatccg aagaagagtg gtctggattt gaaatgctca
     1681 caaaaatgag tattccagtt atcgcattga attgtccaga aggaccagca ggtattgata
     1741 caatattagt gaatgatcga gaaagtgtag caaaagtgat cgctcatcat ggtgaacaag
     1801 gacataaaaa aatcggattt attgctgcca ctcaaacaga ctacgtagca agagaacgtt
     1861 tagcaggagc caaagaagcg gtccaaaatg atccatcgat ccaattagag gtctttacag
     1921 gagactattc tagaaaaagc ggctattacg gggcaaaagc attattagaa aaaggggcaa
     1981 ctgctatttt tgtcagcaat tacaatatgt cgattggtgc catcgaatgt ttcaatcaag
     2041 aaggtgtcag aatcgggaag gatattgcgt tcagtcacta tgattattta gataaaaacg
     2101 atctgagtat ccttccgaaa atcacgatca cgccaccaac agataaaatc ggggaacgag
     2161 cagcagaaca gctgttaaaa cgaatcaaaa aagaagagga agaaaatgaa aaagtgattg
     2221 tgatggaaaa tatcatacat ggaatcaact aaaacgaact aaaaaagaaa aagaggtgct
     2281 ttgatgaaaa aatatcaatt tccagcaaat ttttggtggg gttctgcagc aagtggccca
     2341 caaacagaag gaaggatttc aggcgatgga aaaggagaga acatttttga ttattggtac
     2401 aaaaaagaac cgcaaaagtt ctttgatcaa gtaggacctg aaaaaacctc gcaagtttat
     2461 acgaagtatc aagaggatgt acagttgatg aaacagactg ggcataattc atttcgaaca
     2521 tctatccaat ggagccgttt gatacctgat gaatctggaa caatcaacga agaagccgtt
     2581 cgtttctatc atcgttattt tgatgagttg attgaaaacg gtatcgaacc ctttgtgaat
     2641 ctgtatcatt tcgatatgcc gatgtatctg caagaaaaag gcggatggtt gaaccgagaa
     2701 acggttgaag cctatgaaaa atatgccaaa agttgttttg aattgtttgg ttcgaaagta
     2761 aaaaaatggt ttactcataa tgaaccaatc gttccagtcg aagcaggtta tttatatcga
     2821 tggcattatc cagaagagtc agatatgaaa aaagcgatcc aagttggcta tcatgaagcg
     2881 ttggcttcag cgttagccat caaatcttac catgaaatgg agcaaggtgg tgttattggt
     2941 atcatcttga atctgacacc aagctatcca agagacgaat caaaccctga agatgttaaa
     3001 gcagcgcaaa tagcagatgc gttcttcaat cgttcattcc ttgatccagc tgtaaaaggc
     3061 gagtttccaa gtgaattgat tgagatagta aaagaacttg atctcatgcc tgtgatccat
     3121 gcagaggatt tgacggttat caaagaaaat acagtagatc ttttaggtat caattattac
     3181 cagccacgcc gggtaaaagc aaaagaaaca ccaatcgata ctaaaaacgg tccaatgcct
     3241 gaggattatt tcgacaatta tgaaatgcct ggtcgtaaaa tgaatcctta tcgcggatgg
     3301 gagatctatg aacaaggaat ctatgatatt ttgatcaatg tacgagatca ttatggaaat
     3361 atcgactgct ttatttctga aaacggtatg ggtgtagaaa acgaagcacg atttatcaaa
     3421 gaagatggca tgatccacga tgattatcgg atcgaatttg tccaatctca tctgaaatat
     3481 gtccatcaag ccattcaaga aggtgccaat tgtttaggct atcatatgtg gacatgtatg
     3541 gataactggt cgtggaccaa tgcatataag aatcgatatg gctttatttc agtagactta
     3601 gcacaagatg gaaaaagaac aatcaaaaaa tcgggtcatt ggttcaaaga cgtatcagat
     3661 aaaaacggat ttgaggctta agaaagaata gttgagagca aatgcgtgaa attctccatt
     3721 cttaccattt tgtgaaaaag aagttcaatt atttacgatc tttttcaact tttttgtctt
     3781 tctatttcat tttttgtata taatagaata gtcaaaatta aataggagtg gaggaaagca
     3841 tgaggaaaaa aagaccgttt cttctctttt ggttattcgg ttttttctta ctgcttattt
     3901 tatccgcagc attttcagga aaaatgacag cagatcttgc tcagaaagaa acagaaaaaa
     3961 tcgtagcaag caaagaatca gtagataatt tcaaaaaaga attctcaact tattggtggg
     4021 cggagtataa aataactgcc aattacgaaa aaggcgaatt ggacatttat ttgccaaaag
     4081 gaaaagaaga aaatcaattt attaatatcg atgacgtact tagtgcgatt tctctcagac
     4141 aatatcaatt taaagacaag catttgaccg ttttgctttt gactcatgat ggcgacaaag
     4201 tagcccgttt gaaaaatgga aaagtgatca ccgcttattc tgaaaaagta gacaaaaaag
     4261 tggtcgccga tcgtttagcg gaatggaaaa agacaaatga acaagtcaag aaaacaactg
     4321 tctcttctca aaaaaacgag tcgacaggaa caagtccttc agattctggc agtggacaaa
     4381 cgataacggg aagtgaagaa aatcaagcct caattattac gaatgagtca tcacaaggac
     4441 aatatcaatc ctatggacaa tgaaaaacag aggttgtgaa atcagcgttt tgacctgagt
     4501 attagagaaa caaacggcaa aatagttcct catattttgc cgttttttga gctaataccg
     4561 aaggtcagct gattgaacac cgtgtatcaa gaggtcttga gcctgccgtt taactctgag
     4621 ccacaaggag caatttcaaa aaatagctcc ttatattttt cgtttggttg ggcttattac
     4681 cgcagatgca agcttttgaa caccgtttac caagaggttg taaaattagc gtcctgacat
     4741 aatctaatac cgagggtcag ctgattgaac accgtgtatc aagaggtctt gagcctgccg
     4801 tttaactctg agccacaagg aacaatttca aaaaacagct tctcatgttt tataaatatt
     4861 gtgacttgtg gccgaggagt tggcaggaga acaccgttta aggaagaagt tgtgaaaaag
     4921 ctgtcctgca tcaagaaata aggagctgcg acaagaattt tgtcacagcc tctttttttg
     4981 tacgaatacc gagaaactgg cttttgaata ccgtggagtg aagcggtcac cacaagactt
     5041 ttatctcttc attagtttaa tcgcttacat cgcagcggtt ttatgctgtg aaaagtggac
     5101 ggaataatct ttagaaagaa taaaaaaatc ttaagataac aactttttta ggaaattttc
     5161 atttttcagg agcaaaataa gaaaaaatgt gaatagagag aagtgatata cgtgacacaa
     5221 cttaaaaaat tgtgccaaaa tcgtttagca atcgttttga cagctgtttt ctttttctgg
     5281 ctgaagacga tcattgccta ctatgcagat ttttcattag gtgtggaagg tacgatccag
     5341 tactttatct tgtggatcaa cccaattgcg actaccttat tgttttttgg cctttctttg
     5401 tatattaaaa agccaaagcc agcgttagct attcttttga tcattgatat tttaaatacg
     5461 cttttgttgt acttgaatat tattttttat cgggaattca cagatttcat tacagtcaaa
     5521 tctgtattag gcttttcgaa agtgtcgcaa ggattgtcag gaagctcctt ttctttgatg
     5581 aagccccatg atgtcatcta ctggctggat atcgctgtgt tcattgggct actggtttgg
     5641 ttgaaggtca agaaaatacc tatcaaaagc aaccctgtcg gcaaaccgat ggctatcgct
     5701 gttacctgtc tttcagggct tattttttca ggaaatctag cgctgagcga agccaaccgt
     5761 ccacaattgc tgcagcgaac atttgaccgt tcatatattg tcaaatatct aggaatcgat
     5821 gcgtatacta tttatgacgg aatcaaaaca ggaatgacta gcagtgttcg cgcgcatgca
     5881 agcagtaatg ggattgatga agttttagat tatacaaaga aacattatgc agagccaaat
     5941 cccgaaacat ttgggatcgc taaagggaaa aatgtgatcg ttctccattt agaaagtttc
     6001 cagcagtttt tgattaatat gaaggtagac ggacaagaag tcacaccgtt tttaaatagt
     6061 attttccaga atcaagcaac gatcagcttt gacaatttct ttcatgaagt aggacaggga
     6121 aagacaagtg atgctgaaaa tatgttggaa actggcacat ttggtttacc tcaaggctca
     6181 ttattcacag aacttgggtc agacaatgtc tttcaagccg caccagcgat ccttggacaa
     6241 aagcaaggct atacaagcgc tgttttccat gggaatgtag ctagtttttg gaatagagat
     6301 catgtatata aaaacttagg ttatgacaat ttctttgatc gatcttattt tgatgaatcc
     6361 gacgaaacgt taggttatgg gatattagat aaagatttat tcagagaatc tgcccaatat
     6421 cttgagcatc tacaacagcc gttttacacg aaatttcttt ccgtaaccaa ccacacgcct
     6481 tattatacgg atgacaagaa tttcgacttt ccatctttga atactggcaa tagcacagta
     6541 gataattatg ttcgaacggc acattatctg gatcaatcat tggaacaatt ttttacgtat
     6601 ttgaaaaaat ctggtattta ccaaaattca atctttgtga tttacgggga tcattttggg
     6661 atctcgaata cagataataa agatttagca agcgctcttg gtaaagatcc agatacatgg
     6721 gatgaatttg acaacgcaca gatgcaacga gtgccattga tgatccatat gcctggttat
     6781 actaaaggga cagtcaatca tgaatacggt ggagaaatcg atgttttgcc gacattacta
     6841 catctattgg gaatcgatga taaagattat cttcattttg gtacagactt attatcttct
     6901 cagcatgatc aagtagttgc ttttcgaaat gggaactttg tgacacccaa atacaccgtc
     6961 ctaggaggaa aagcttacaa taatcagaca ggagaaatca tcgatacgaa agcagcagga
     7021 atcgatgagg aaatctccaa agatcaggaa aaagtcaaga ctgcgttaag tctttcagat
     7081 aagctgaatc aggaaaatct cttgcggttt tatgtgccaa acggatttga gacgattgat
     7141 ccgaaaaaat atgactataa aaatgaagcg gaacgtaatg aagcaatcga aaagcaaaaa
     7201 ggcgaacatt cgacaagtgt cttttcaaaa aatggtaata aaacaacaac caacttatat
     7261 ccagtaacaa gaacagacgt tgaacagcaa aaaaataatc aataaacaat caaaccaacc
     7321 ttcagtagtt agacaac
//
LOCUS       DAIGUC010000091         7189 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.094, whole genome shotgun sequence.
ACCESSION   DAIGUC010000091 DAIGUC010000000
VERSION     DAIGUC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.094"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(31..1437)
                     /gene="lpdA"
                     /locus_tag="NOB46_002614"
     CDS             complement(31..1437)
                     /gene="lpdA"
                     /locus_tag="NOB46_002614"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCI1059514.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            complement(1445..3088)
                     /locus_tag="NOB46_002615"
     CDS             complement(1445..3088)
                     /locus_tag="NOB46_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCI1059515.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            complement(3113..4090)
                     /locus_tag="NOB46_002616"
     CDS             complement(3113..4090)
                     /locus_tag="NOB46_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCI1059516.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            complement(4093..5202)
                     /gene="pdhA"
                     /locus_tag="NOB46_002617"
     CDS             complement(4093..5202)
                     /gene="pdhA"
                     /locus_tag="NOB46_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HCI1059517.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            complement(5663..7087)
                     /locus_tag="NOB46_002618"
     CDS             complement(5663..7087)
                     /locus_tag="NOB46_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI1059518.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
BASE COUNT         1855 a         1612 c         1297 g         2425 t
ORIGIN      
        1 ttcagttgcg tttcgcctgt attattcaaa tcaaatatgg attggtaaac ctaatgctaa
       61 ttccgaagca tccatgacga tttcgccaag agatggatga ggatgaatcg tcaaggcgat
      121 atcttcagca ttcattcctg attcgattgc taaagctaat tcagagacca tatcacttgc
      181 gccgactcca ccgatttgcg cgccaataag cacgttatct tcgatcgtcg taactagacg
      241 gatgaatcct tctgttttac caagcgataa tgcccgaccg ttccctgaaa atgggaattt
      301 atatgctttt gcttcgatac cagcatcttt tgcttctttg atcgtcatac ctacagaagc
      361 caattcagga tcagtgaagg ctactgccgg cattgcttta taatctacag ctactttttt
      421 gccagagatt gcttcagcag cgatttttgc ttcataactg gctttgtgtg ctaatgccgc
      481 ccctggaacg atatcaccga tggcatagat gttaggtacg ttcgtacgtc cttgtttatc
      541 caccgtgatc aatcctcgtt ctcctacttc gacacccgct tgttctaagc ccatatcatc
      601 tgtattcgga cgacgaccta cagtgaccat cacataatca gcagtaacgg attcttcttt
      661 cccgtccact gcatatttca ctgtcacgct gtcaccgtta tcgactgctt ctttcgccat
      721 tgcattcgtt acgactgtta cgcctttttt cttgaaatca tcttctacta attttactag
      781 atctttttcg taagttggta aaatttgtgg tgagccttca agaatcgtta cttctgctcc
      841 taagtttgcg tacgctccgc ccaattcggc accaatcaca ccgccaccga tgatcacaaa
      901 tttcttaggt acttctttca atgctaatcc gccagtagaa tctaacacac gtcctccgaa
      961 tttaaatcct ggaatctcga ttggacggga acctgttgcg atgattgcgt tattgaacga
     1021 ataagtttga gctgaatctg gatgaatgac gcgtagtgtg tgatcatcta cgaagaacgc
     1081 ttctccttcg attgtttcaa ccttatgttt ttttaatagg aaaccaacac cagaagtcaa
     1141 cgtatggaca actttgtttt ctttccattc ttgtgttttt gcaaaatcta gtttgacgtt
     1201 ttcactagtt actccaaaca tttcagaatc tagtgactct tgataatggt gtcctgcagc
     1261 tatcagtgct tttgaaggaa tacagccgac attcaaacaa acaccgccaa tatactctct
     1321 ttcaatgatt gctacttttt gtcccatttc agcagcgcgg atggcagcta catagccacc
     1381 aggtcccgca ccaattacaa ctgtatctaa ttctacagca aaatctccaa ctaccatttg
     1441 tttatcatcc ttccatcatt aatagctctg gatcagctaa aagacgtttg atattattca
     1501 ttgcttgttg cgcagttgct ccatctacga tacggtgatc gaaacttaat gacagtttca
     1561 tcacacgacc gacaacgatt tcgccttcag catttacgat tggttgttgt gcaatcgttc
     1621 ctacacctaa aatagctact tctggatagt tgatgactgg tgtaaaccaa ccgccaccta
     1681 cagatccgat attgctgatc gtaattgttc cattgcgcat atcttctgca gatagtttgc
     1741 cgtcatgagc taattttgct ttctcattga tttcgtctgc aatagcaaac attcctttgc
     1801 ggtctgcatc tttcacattt ggtacatata gtccgtgatc cgtatcagtt gcaataccga
     1861 tattgtagta atgtttataa acgatttctt ggtttgcatc gtcgatagat gcattcaata
     1921 ctgggtattt cttaacagtc gctgttaaag ctttcacgac atatggcaag aaagtaagtt
     1981 tcgtaccatt tgcagcagca acttctttaa atcgtttccg attatcccat agtttagaca
     2041 cttctacttc atcatgcaat gtcacgtgtg gagctgtatg cttactgttg accattgctt
     2101 tagcgatagc tttacgtgtt ggcgtcattg ctacacgttc ttccaagtct cctaagttgg
     2161 acttgaatgg ttttgctggt gcagctggtt tgctttctgc tgcaggagct gcttctttcg
     2221 gtgctgccgc ttctggcgct tctgatttcg ctggtgcact gcttggacca cctgccaaga
     2281 agttttcgat gtcctctttt gttactctgc caccttttcc agttgcagtt acttgtgaga
     2341 tatctacatc tttttcacgg gcaaattgac gaacagatgg catagccaat acacgtttat
     2401 ttggatcggc agcttcaacg acacttgctg aacctgatgt ttccactttt tcttttggtg
     2461 cttcagctga tggcgcacta gttgacggtg cactattgtg tccaggagca tcgatttcta
     2521 ctaatacatc cccaacattt gctacagtgc cttctggaac aatcacgttt ttaactgtcc
     2581 ctgtgacagg tgacggaatt tcttctactg atttgtcatt ttgaacttct agtaatgtat
     2641 catcttcatt gatcgtatct cctggtttga cgaaccattt gacgatttca ccttctgcga
     2701 ttccttcacc gatatccggt aacttaaatt ggaagactcc ttcgcttgac gatccagctg
     2761 attctgtatc aacagtgggt tcagcagccg gtttagctgg agtttgggat tctgcggcta
     2821 caccactgtc cccttcattg tcttcgtgtc ctggtgcatc gatttctact aatacatccc
     2881 caacatttgc tacggtacct tctggaacaa tcacattttt aaccgttcct gtaacaggtg
     2941 acgggatttc ttctactgat ttgtcatttt gaacttctag taatgtatca tcttcattga
     3001 tcgtatctcc tggtttgacg aaccatttga cgatttcacc ttctgcgatt ccttcaccga
     3061 tatccggcaa tttaaattga taagccatga ctttgtttcg tcccttcttt tcttaaaatt
     3121 ccgcgatttc ttttactttg tcttcgatat cttttgcatt tggcaaccag acattttctg
     3181 cttgtccaaa tgggaagact gtatcaggtg cagaaactcg tccgattggg gcttctaatg
     3241 aaaggatagc gcgttctgag atctcagaaa ctacttgcgc ggcaacgccc gcttgtcgtt
     3301 gtgcttcttg gacaacaact acgcgaccag ttttttccac ggattgaatg atcgtttcta
     3361 catctaatgg cgcaactgta cgaagatcaa tgatttcaac agatatattt tcttttgcaa
     3421 gattgtctgc tgctttgatt gcttcacgca ccattgctcc gtatgtgata atagatacat
     3481 ctgttccctc acgagtaact gctgctttat ccaaaggaac ttcgtaagct tcatccggca
     3541 cttcttctcg gaatgagcga tatagtttca tgtgttctag gaaaacaacc ggatcgttac
     3601 ttctaataga agaaatcaat agtccttttg catcataagg gttggaagga atcactactc
     3661 gaataccagg agactgagcg atcaaacctt ctaaattatc cgaatgcaat tctggtgtat
     3721 gaacaccgcc accaaatggc gaacgaattg tgatgggtag atttctagtg ccgctcattc
     3781 gatatcttgt acgagccatt tgagctacta cttcgtccat tgcttcgaaa ataaaaccaa
     3841 agaattggat ttcaggaact ggacgaaatc cttctaacgc aagaccgaaa ctcaatcctg
     3901 cgattccaga ttcagctaaa ggagtatcga atactcggtc ttctccgaac ttttcctgca
     3961 atccttcagt tgcccggaaa actcctccgt ttttcccaac atcttcacca aaaacaacga
     4021 cattctcgtc attttctagt tcaagtgcta aggcatctgt gattgcttgg atcattgttt
     4081 tttgtgccat gattatttcg actccttcgc ttcataaatt gcaatttgtt ctttgattga
     4141 ttgtggagat acttcgaaca tgtttttcaa gaaatctgaa accttttgtt ttggtacttt
     4201 gtcggcttca gcaatagctg ctttgatttc ttctttagtt gcttcgatga cttgttcttc
     4261 tttttcttca gaccaaagtc ctttttccgt caaatattta cggaagcgga tcaatggatc
     4321 ttttttctgc caatcgtcat ctgtgtcttt tgtacggtag cgggttggat cgtcaccaga
     4381 tagtgtatgt ggtccataac gataagtcag tgtttcgatt aggactggtc catttccact
     4441 gatcgcccat tcccgtgcca ttttagatac agtatatact gcaagcggat ccattccatc
     4501 gacttgaata ccaggaatcc cagctgcgac agctttttgt gcaagtgttt ttgctgcagt
     4561 ttgtttttca cgaggtgtag agatcgcata cccgttgttt tggatataaa atacggcatt
     4621 tgcatggtaa gcgccagcga aattgattgc ttcgtaaaaa tcaccttgtg atgaaccgcc
     4681 atcaccagta taagtgaaga cgacattttt cttgtttcgt ttcttcaaac ctaatgcaac
     4741 accggctgct tgtacatatt gtgcaccgat gataatttgt ggtggtagag ctttcaattc
     4801 ttccggataa gaattacctg cagcatgtcc tcgagaccat aaaaaagctt gagataaagg
     4861 taaaccatgt tttactagtt gaggtacatc ccgataacct ggaagaagaa catcttcttt
     4921 atcaaatgcg taagcactag ccagctgact tgcctcttgt ccagcagttg gtgcaaaaaa
     4981 gcctaggcgt ccttggcggt tcagcgctgt tgaacgttgg tctaatacac gagaccatac
     5041 catatgagtc attaattcaa cgagttcatc atcggataaa tcaggtacta aatctttgtt
     5101 aactacgttt ccatcttgat caagtgcttg atatactggg aaatctgcat tgacttcatc
     5161 tagcagtgct tggaagtcga tcggtgcttt tttgtttgcc atttgtcaca cattcctctc
     5221 tcatctataa gaaaatctct tcattctgcg attgaaacag tgaataaaac tgtatcacta
     5281 tttaaccgtc ttcattaata aattatcatg gatttatgag aaatacaagc taaaagcaca
     5341 aattttcacg atgaaaggaa attatgccaa tccgcatatt aacagcatta gtgaataaaa
     5401 tcacaataag gaaagcgttt tatatttcat ctgcattttt tctattttct aatcaaactt
     5461 acaaccatct gtttctattt aaaaacgttg gtgttataca gttttgttgc aaacatttat
     5521 tttatttaca catcgtgaac ggacgtacaa ataatggttt tttcttagtt tctttatatc
     5581 gtattctttt tccgaaaaaa aagaaacagc ttgaaattta aatccaagct gttatattct
     5641 ttaatctatt tactttgtga aattattctg ttaaccactt ttctagaatt ttcatctttg
     5701 aataaaacaa cggtatttgg ttttcatcca gcctactgta attgattctg attccattta
     5761 tatcttgccc aaaaagtaga cttggtgcaa ttccaagacc catatctact actttttctg
     5821 ctagttcggg gtctagtttt ttcccatccc aagtaatcca ggcatagtaa ccacctaaaa
     5881 ttgaatgaag cttgaaaaac gattgtgaat ctccccaagc gcttatcagt cggctttttt
     5941 ctttcaactt ttttcttaca tcttgcattt tcaaatcaat tgcttcatta aatacattag
     6001 ccactgtgat ttgtgtaagg atattcatcg aaaactccat catttcttgc gcttgagcta
     6061 gttgcgagat aaaagtctca ggtcctatca cccaaccgat tttcgttgtt tttcctaaaa
     6121 ccctagataa cgaaccgacg tataacacat tatccggatc aatcgttcgt ataggaagga
     6181 cttcttcttg gtttagaaat gaaagatccg taaatacatc gtcttcaata attggaagcc
     6241 gatactgtcg acacaattct actagctttt ctcgtcgttt ttgactcatc acttttcctg
     6301 tagggttttg aaaattcggg ttgataagca ctgctttcaa tttattttta tggatcgatt
     6361 ctttcagttt ttctaagtcg atcccttctt catccatcgg tatcccaaat aaacgcgttc
     6421 ctgaagcttt gaaaagaggt aatcggtaaa aaaaagaagg tgactctaca gctatcccct
     6481 ctccagctga aagaatcgtt tgtaaaatca aaaagattgc ttgctgaccg ccaccagtca
     6541 caagaagctg gttgggggaa aatgccaatt caaatttact ttccaaatac cgtttgattt
     6601 tgttacgtaa cggagtatag cctaaaagat ccatttcttt ttcttccgct aagatttctt
     6661 caagagaata agaaggaaac tcaaaattcg gcaaaagctc atctggcatc tcgctagcgt
     6721 ataaatcaag aaacgatgtt ttttggatct gctttgcttc tcttattttt tgctcatacc
     6781 agtccgtctg ctcataacga ggagagatca tttgccgcca atcgattctt ggaacagcga
     6841 atttccccca ttcagtctga ttaacaaacc atccgctgcc acgtttgctc gttagtaccc
     6901 caagctccct aagctcttcc aatgcatgga caacggtgga acgattcaca ccaaaaagtt
     6961 gccctagttt tcgttctgat tcaagttgac ttccaggatt gatccttccg ttttcgattt
     7021 ctctcataat ctgttccata atttgacgat aaatcggtcc ttgttttttc tctacttttt
     7081 cccacataag cttctctttt ctattgtcta ttttttcttt tgattttacc gaatttacga
     7141 gaaaaaagaa aaactttttt tgcaaaacat aagggactgt gacaaaaat
//
LOCUS       DAIGUC010000092         7162 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.095, whole genome shotgun sequence.
ACCESSION   DAIGUC010000092 DAIGUC010000000
VERSION     DAIGUC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.095"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            236..1627
                     /locus_tag="NOB46_002619"
     CDS             236..1627
                     /locus_tag="NOB46_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI1059519.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAESAFPKEKTYR"
     gene            1665..2495
                     /locus_tag="NOB46_002620"
     CDS             1665..2495
                     /locus_tag="NOB46_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI1059520.1"
                     /translation="MENKNISILLSLYDKEKPEYLKEALASIFEQTVMPAEIVLVYDG
                     PINEKLQAVVTYFQQKVPHLFTVVKLEKNQGLGIALATGLEHTKNRLVARMDTDDIME
                     PHRLEKQLEIFQEYPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFN
                     HMTVMFDKNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYAR
                     RGGSKYLLPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN
                     "
     gene            2467..3456
                     /locus_tag="NOB46_002621"
     CDS             2467..3456
                     /locus_tag="NOB46_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1059521.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLRRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNYGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNHPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            3570..4565
                     /locus_tag="NOB46_002622"
     CDS             3570..4565
                     /locus_tag="NOB46_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI1059522.1"
                     /translation="MHKISVIVPAYNVENYLENCLESISNQTHSNIEIIVVDDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILVFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
     gene            4569..5711
                     /locus_tag="NOB46_002623"
     CDS             4569..5711
                     /locus_tag="NOB46_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HCI1059523.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQFYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSEK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNLMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELLERDIK"
     gene            5708..7135
                     /locus_tag="NOB46_002624"
     CDS             5708..7135
                     /locus_tag="NOB46_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI1059524.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFLQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIAGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIILFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPLFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTALSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVVLFFIVNLTLTTSAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEVRKIIRK"
BASE COUNT         2558 a          932 c         1260 g         2412 t
ORIGIN      
        1 tatgaatatt gtaacttgtg aataaggaat tagcaggaga atactagttc agcataaagg
       61 aagtgatggg acttctgaga caactttctg ttatgcagaa atacacatat aaacagacaa
      121 taaacgcttt tccccgtttc ttttaatttc ctttacaatt tggttattca ctaggttttt
      181 aaactttgct atggtaagat gatagaggca ttattttatg gttaggagtg tatatatgaa
      241 taaaaatggg gagtggaatg cggcacgcag aatattcatt attcttatgg atgtacttgt
      301 attaaatgta tcgatctatc ttagtttttt gctgaaattc cagggagaag taccagtgag
      361 aaacttagaa acctttcagc attcagcaat ttttatttcc atcatcttta ttgcgttgaa
      421 tattttgtta ggagcttatg tattctataa ccgaatgatc agtgatattg tcttcattac
      481 tgttattgga caagtactaa tagcattggg gatcatggta gttacttttg ctggccgatg
      541 gtttgcattt ccgcgtggcg tcattttgat ctcgtttatc ctaggtacga tattacttag
      601 tgtttaccgg atagtcgttt acaaactgta cttaagagtc agtcgtgata agaaagtcct
      661 tatcgtgggt ttggagaaag atgtcgcacc agctatccaa aattttcaat ctaagaaaaa
      721 caataaacat aaggttgaag cagtggcaat cgataattat tacgaaaata caaaaaaatt
      781 gatcgatgat atggatatcg tctatttggc ttctaaaatc ccagaagatg aaaaaatcaa
      841 catttatcaa ttagtgacta aaaaagagaa gaaattattt ttaaatacga cttttgagaa
      901 tctgacaatg ataaatccga atattatgaa ttttgaagat gaaagcatca ttgaagcttc
      961 tgggttcaga atccaaccag aatacgaact attcaagcgt ctctttgata tcatcgtttc
     1021 gcttatttta ctgatcctcg cctcaccttt tatgctaatc acagcgattt tggtaaaaac
     1081 aacttcacct ggaccaatca tctataaaca agtacgtatt acgaaaaatc aaaaggaatt
     1141 ttcaatctat aaattccgtt ccatgagtgc gacagctgaa gcaaaatcag gaccagtctt
     1201 ggctaaaagt aacgatgcac gtgtgacacc agtaggtaaa tttatccgtg ctgtacgttt
     1261 tgacgaatta cctcaaatct ttaatgtatt gaaaggcgat atgtcgattg tcggtccaag
     1321 gccagaaaga ccatttttcg ttgatcagtt caatgaagaa aatccttatt attacttaag
     1381 acacaatgta cgtgcgggaa ttaccggata tgcacaagta tacggaaaat atgtatcaga
     1441 ttataacagt aaactacgtt ttgatttgtt gtatatcaaa aagtattcct tactattaga
     1501 tttgaagatt ttacttcaaa caatcaaaat cttatttgat aagatgtcct cacaaggact
     1561 agatgaagat gaaaatatca gttcattagc agaaagtgca tttccaaaag aaaaaacgta
     1621 tcgttagatt ggaaaaattt tgagcaaaga agtaggagag aacattggaa aataaaaata
     1681 taagtatact gctttctttg tatgataaag aaaagccgga atatttaaag gaagcattag
     1741 ctagtatctt tgagcaaacg gtgatgccgg cagaaatcgt attggtttat gatggcccta
     1801 taaatgagaa gcttcaggca gttgtcactt atttccagca aaaagttcct cacttgttta
     1861 cagttgtaaa attagaaaaa aatcaaggat tggggattgc tttagcaact ggattagaac
     1921 atactaaaaa tcgcttagtg gccagaatgg atacagatga catcatggaa ccacacagat
     1981 tggaaaaaca attagagatc ttccaagaat atccagaaat agcgattgtt gggagtaata
     2041 ttgaagaatt tactggcaca cttagcaatg ttatcggaag aaggattgta cctgagtata
     2101 atgatgaaat ccgtgtgttt tcgaaaagaa gaaacccttt taatcatatg acagtcatgt
     2161 ttgataaaaa tgctatttta gaagtgggaa actatcgccc attaattgga tttgaagatt
     2221 attatttgtg ggtaagacta ttgaaggcgg gatataaagg atataatatc caagagattc
     2281 tagtacatgc tagagcaggt gctgacatgt atgctagacg tggaggaagt aaatatcttt
     2341 taccaggaat taaaggccga tatcgcgtat ggaaagatgg tctaggatca ctaaaagatt
     2401 ttctgatagt tatttgcgga catcttgtaa ttagtttatt accgaataaa attaggggaa
     2461 aagtatatga atcaaaactt agaaaaacaa actaaacttt ctataatcat acctttttac
     2521 aatgcaaaga atactttaag aagagctgta gacagcgtct taacgcaagg ttatcccaat
     2581 attgaaatct tgttaattga tgatggatct acagatggta gtagtgacat tggtgacgaa
     2641 attgctaatc tagagagtaa agtagcatgt tatcacttgg aaaacgctgg tccatcagtt
     2701 gctaggaact atgggataaa agaagcaact ggaaatttgg taggattttt agatagtgac
     2761 gattattttt tacctgattg ttttaataat gttttgaaag actaccatag gaatcacccc
     2821 gatatcattg cttttggatt aagtaaagga aaaaatatag aaaatgcaaa tttatttgtt
     2881 cccgaaaaga agattggttg ttcaagtgaa gaagcaattg agcaaatgtt tagaagtaag
     2941 gcagtggact tttacgtatg gaataaattt tttaaaaggg aattattcaa tcatatagtt
     3001 tttccagaaa ataaattata tgaggatatg gttcctatgt atgaagcttt tagggcggct
     3061 agtaaaattg atattttgcc attttcaggt attttttatt atcaaaataa cgatagcatc
     3121 gtttatcagt cttttaattc aaaacagtat gataatattt tgcagagaaa aatattagtt
     3181 gatgaagtaa agaaagatta tcctcgactt attaatttgg ccaatgctcg gttagtagac
     3241 ggatatcttt caacagggtt taaaattact ggcaaaaatc aaaatcagaa agaaaaacaa
     3301 aaatattata atcagtctaa aagagaaata aaaagtatat attcaaaaat aagaagtaac
     3361 aatgagatat caattgctaa aaaattagct ttatttttat acttaattaa tcctaaaact
     3421 tattttattt tatataaaaa agttctaaaa aaataaagtt tttttcgata tgttattttt
     3481 tatgtttatt aacttcggaa gactaaaatt gttactggta atgatacatt tgtaaaaata
     3541 aaaaagatga tttttaggaa gtgaagagag tgcataaaat tagtgttata gtacccgcat
     3601 ataacgtaga aaactattta gaaaactgct tagaatctat ttccaatcag acacattcaa
     3661 atattgaaat aatagtagtc gatgatggtt ccccggatcg aagtggggaa attgcagaag
     3721 aatataaaaa gaaagatatg cgattaaaag tgatacatca agtgaatggt ggtttaagtg
     3781 cggctaggaa ttctggtctt gattctgcaa caggagattt tgtgtgcttt attgacagcg
     3841 atgattggat agaaccagac tatcttgagt tactatattt tggtacgcaa acttatggag
     3901 cagatatctc ggtgctaaaa ataaaaaaga tttcaagttt agaacaacta aaagaacata
     3961 caattgctga gagaaaatgg gaaatatttg atagagaaca agcaatgaaa aacttattta
     4021 taaataataa aattggctat tctgcaaata ataaattatt caatagaaat ttatttgata
     4081 atataagatt cccactgggt aaattaatgg aagataaggc tactacttat ttgttgatcg
     4141 atcattccga aaaagttgct gtcaattcat ctgctaaata tcactattac caaagcccta
     4201 aaagtatact gagaggaagc ttcaatccta gaatttttga ttcttttgaa gtccatgaag
     4261 atatactagt attcatagat aagttttatc cggaattatc aattaatgtt agaactcgct
     4321 atgtctatga agcaataagg atgatgatga caatgattaa aaataactat accaataaag
     4381 aagattattt acgttctata aatattttac aacgctttga aaaagaagtg aaaattgatc
     4441 ccgacttttc accaaaatta aaaaaattag taaagttttt attaataaat aaaaacttgc
     4501 cttactatat gtcaagtagt aagatagcaa gtaaattttt gattaagata gaatctgtga
     4561 ggtaagagat gaagaatata aaaaaatttt tttcaaggaa tattttcccg gtttttatta
     4621 aaatattacc tattcaaaaa aatttaattg tattttcaag ttttggcggg cgtaattatt
     4681 ctggaaatcc aagagttatt tcagagaaaa ttcatgaaaa aaaattgaat tacagaatta
     4741 tttggttaat caaaaaagaa gcgattataa ctgatttacc agattatatt aaaagaattg
     4801 attccgattc ttttttagct gccttttatt tgtatacagc taagtattgg atagacgata
     4861 gtcggaaaac gattaagtat gcaaaaagga aaaaacaatt ttattttcaa acatggcacg
     4921 gtacgccttt aaaaaaaatt gaatttgatg caaaagataa gttacctaaa cgttacctaa
     4981 gctatgcgaa aaaagatagt gagtcaatta catatttatt atctggtaat cgctatagtt
     5041 ctgagaagta tgtttcagca ttcaatatcg ttccttctaa aatattagaa gtaggaactc
     5101 ctagaaacga tgaattagcc tctagtaaag agcaagtgtt tgacttgaaa aagaaacaaa
     5161 tcaatgtctt atttgctcca acttttcgaa ataatattga ggacaacgga attacgcaac
     5221 tagaatggtt aggtgtggat aacttacgtg aattttttaa aaagcaacaa caagaattaa
     5281 atttaatgac taaatttcat cctaatgttc atagtaaatt agcaactgat tctaaaagta
     5341 tagaatatat gaaaaaacat caaattactt taattaatga tgggattcct cttgaaatgc
     5401 tttttgaaga gatagatgtt ttaatcacag attattcatc tatttttttc gattttgcgc
     5461 taacaaaaaa accaattatt ctttttaact atgatgaaaa agaatatagc ttagaaagag
     5521 gtttttatat acagttaagt gagttaccaa ttataagcgt acaagatagt tatggccttg
     5581 ttgatgtttt taaaaaccaa caagaaaagc ttttgaaaag ttctcaagag ttacttgatt
     5641 atattggaaa ttatgaaaca ggggcaagta cagaaaaggt tcttgagttg ttagagaggg
     5701 atataaagtg aaaaaaacag taaaagatat attttataat gcgatatatc aagtcttttt
     5761 gattgttttg cccttactta ctatacctat acttagtcgt agaataggtt caactggttt
     5821 agggatttat gggtatgttt tctcaatatc acaattttta atgactgtca ttgctgtggg
     5881 aatgaatcct tttcgtattc gaaatatcgc taaatcaagg aaagataaaa aagcactatc
     5941 tttacaattc tggaatattt actttcttca atttttaata ggcttgagtg tttcctttct
     6001 ctatatagcc tatatttatt tttttgatgt aaagtataaa aatttatact taattcaatt
     6061 gatatttatt gcagggctaa cattagatat ttcttggttt tttcaaggaa ttgaagaatt
     6121 ttcgaaagtg gttattagaa atacagttat caaattatca tcggtattgt taataatcct
     6181 ttttgtttca actaaagatg atttgtggat ttatgtgttc attacttcaa ttactaactt
     6241 tttaggaagt ttagttttct ggttgagtat ccacggaaaa gtaggtaaac cactctttaa
     6301 ctctaatgtt tttaaacagt tgtggaaacc agcttttatt attttgactc ctcagttgtt
     6361 tatgcaagtg tacacaactt tagacaaaac gatagttggg tattttgtgg atccaacagc
     6421 attatcttat tatgatcagt ctcaaaaaat tgctcgtatt atattggcag tcttaacatc
     6481 aattactatt gttatgttgc ctaaaatatc taaagcacag gcagagggaa aatcagaaaa
     6541 tattttagtt tacacaaaaa aatcttttga ttacacgatt attattgcat taattctttt
     6601 tagtgtggtg tttatcaata caaaagaatt tgttccatgg ttttttgggg agaatttcaa
     6661 accgatgaca ataaacatgc ttatttcttg tctaattata gttgttagtc caattggtgg
     6721 agtttttgct aaccaatttg caattgctat agaaaaagat aaggagtatg cttatccaat
     6781 gatcattggt gcgattgtaa gtattattgg aaatgtagct tttgtgccta cttatggcgc
     6841 tgtagcggct acaatcgtac tcgtggtagt agaattatta gtctttttct ttagagtatt
     6901 ttttgtacga aaagaaataa aaatatccta tttctttggg aagaacgttg tcttattttt
     6961 tatagtcaat cttactttga ctacttcggc ctattacttt cttccacaat tattctcttc
     7021 ttcattttta gatatggcaa ttaaatcaat aatgattttc attatttatc ttccgtttgt
     7081 ttattttctt tttccagata tacgaaatga agtaagaaag attattcgaa aataaaataa
     7141 tgttgtaaaa aagtagttct tt
//
LOCUS       DAIGUC010000093         7022 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.096, whole genome shotgun sequence.
ACCESSION   DAIGUC010000093 DAIGUC010000000
VERSION     DAIGUC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.096"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..813
                     /locus_tag="NOB46_002625"
     CDS             <1..813
                     /locus_tag="NOB46_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI1059525.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAIKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="NOB46_002626"
     CDS             807..1229
                     /locus_tag="NOB46_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059526.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            1531..1911
                     /locus_tag="NOB46_002627"
     CDS             1531..1911
                     /locus_tag="NOB46_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCI1059527.1"
                     /translation="MSEQNQNLASNYSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            1893..2807
                     /locus_tag="NOB46_002628"
     CDS             1893..2807
                     /locus_tag="NOB46_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI1059528.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            3047..3736
                     /locus_tag="NOB46_002629"
     CDS             3047..3736
                     /locus_tag="NOB46_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059529.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GFIFYLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3857..3943)
                     /locus_tag="NOB46_002630"
     CDS             complement(3857..3943)
                     /locus_tag="NOB46_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI1059530.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            4580..5524
                     /locus_tag="NOB46_002631"
     CDS             4580..5524
                     /locus_tag="NOB46_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCI1059531.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            5545..6081
                     /locus_tag="NOB46_002632"
     CDS             5545..6081
                     /locus_tag="NOB46_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI1059532.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTPILSEET
                     ESIEKHTKKKQKWWQLWK"
     gene            6097..6267
                     /locus_tag="NOB46_002633"
     CDS             6097..6267
                     /locus_tag="NOB46_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059533.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            6681..>7022
                     /locus_tag="NOB46_002634"
     CDS             6681..>7022
                     /locus_tag="NOB46_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI1059534.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2652 a         1212 c         1238 g         1920 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatctcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcgatta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acatgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacggaggca tttggctagc aaatatagag cttgccaaac
     1441 ccttttagtg agctttactc attgtacctt tttaggtaca atggtattgc gaacgatacg
     1501 tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaaaa tttggctagc
     1561 aattattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt tcgagtgagc
     1621 gaatccgaat ttgcaaagct gaagcaatcg gctgaagctt tgcaaatgag tgtgccggct
     1681 ttcgtgaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc gccagacatt
     1741 gcccaggcaa tcgcgcgcga tttagccaaa gctggaggga atatcaatca aattgctaag
     1801 tggtgcaata cacaccaaca tgacgttgct tctggtgacg ctcaacgttt atccgaaaac
     1861 ctaaaaatca tgcaaaagga gctacaaaag atatggcaac aattaaggta agccgaacca
     1921 cttcttgtag tcgtgcaatt aattatgcag aaccacgagc aaccattaaa acaggaataa
     1981 actgtgacgt cgattatgcc aaaagtgaaa tgaaacaaat tcgcatgctg tatggaaaag
     2041 acgaccgtgt acaggcacac ttattgattc aatcttttcg accaggagaa attaccgctg
     2101 aaaaagctaa tcaactaggg gcagagtatg caaaaaaaat agcccccgat caccaaatag
     2161 ctatttacac acatacagac aaagaccata ttcataatca cattgtcatt aactccgtta
     2221 atctggagac tggaaaaaaa tttcaagctc atggtcaagc atttctaaac aaatgttatg
     2281 acctaaatga cgagatttgt cttgcacata acttaccaat cactgagcga ggaaagaagc
     2341 cagaaaaacg aaccatgtct gaaataaaat taaaagaaaa aaatgaacct gtttggaaag
     2401 acgaaattcg gattgcgatc gatcaaacaa tgaaaaacaa aaaaaccaga acctatgacc
     2461 aattttgtaa ttccctcaaa acattgggga ttcattgctt caatcgcggg aaaaatttca
     2521 cttacgaatt gatccacaaa aagaaaaaag tacgatccaa cagactagga aaggactacg
     2581 aaaaggagac gattttacat gagctggaca gacgagaacg aacctataac caacagcgaa
     2641 ccaacgagct acgaagagct cgagctagca ttcgcgaaac tgcagaagaa gtacgaagag
     2701 aacaacgaac tcttacgcct gaacaaccgg aaattagacc ggctcgaaga aaccatgaac
     2761 aacacgttga aagaggaaca gaccaccaac aagaattatc gctctaaaac gttaaaagac
     2821 atagaaaacg aaataaagaa acaacgtgct tttctcgttc cttatacgca agaaaggata
     2881 caaactacga ttgatttaca agttaaaaaa ctccatcaag agctattaga ccagcgaaat
     2941 aaggaacaga aaaaggtgct tattcaacga tcattggatt ttcttgcccc cttatgttgc
     3001 ttagtcctga cactgttcgc attttggtta gtatggggag gctaaaatgg cattttattt
     3061 accctatcta ctcatttttg ttagtatttc aggaagtatt tggctcatct ataaaatttt
     3121 tcaaacaaga tattcattaa aaggctctaa aattcgattt aagcgatttt tctttcttgg
     3181 ctttatattt tacttgataa tcgtttcaag cggcttattc ggcgttttag agggaaataa
     3241 gcgcgtttct agaagtattt tattaggaaa tgtcactcaa aagtatgaat cagcgcgtga
     3301 taaaaagaaa aaagagcaag cattagcaca aaaaatggaa gagtttacca cttgttatga
     3361 ggaaatgaac gatatttttg tgaatcaaga aaaacgtttg acggataaaa atatggaaac
     3421 actcactcga ctttatcgga atttgccaga agaacagcaa aaagagtacc aagaaaaata
     3481 tgaacaagta aaaaaagacg tgcaatatgt gaaagatacg aaagtggaag aagcttgtag
     3541 tgatttattt ggagatacaa ttcctttttc aactagcgaa caagaacgaa aagaacgaca
     3601 acaatcagtc acatatgaac gctatgaaat cttgcttcaa caagcaacga acatacaaaa
     3661 tccaacgaaa aaagaaacgg cattaaatta tctaaaaagt gtcaaggaat ggttagatca
     3721 gcaacagcaa aattgaattt gatcggcaat catgttaaac taaacatgca aatgatcaaa
     3781 cattagatac acgaaagccc cagagaggtc ggattctctg gggctttttt tcaggttgat
     3841 gtcgccttta ttgattttac ttcttgtttc ggttattcaa ccaataactg aataaagaga
     3901 cacaaacttc tataagaagg gggcaaatga acaattcaaa cattagatac acctccttcc
     3961 agtcgcaaga ctgtcggata ggcgacaagt tattatatct taaaaaatta aacttgtgtg
     4021 gtgtttttaa gtatcgctta ttttagggtt gttagggctt gccctgaccg cctgtaaggc
     4081 gctttaaagc tagataagga tttttatcca agactgtctt aaaacggctt agataagcat
     4141 tcagaaccgc tcaaaggcct ctttaccaac atgtttttag caaaggagcc tttaggcgac
     4201 tgcgcagtac aatgtgagag cgtagcgatc acaccttttt ggcgaccgta ggaagcaagg
     4261 ttttggattg gcagttttga aaaatgcgcg aacctgttta aagaaaaaag aagtggtttt
     4321 taggcgggaa aattagcccc cctcttttta tatctctttt taaacctctt tttaaacctc
     4381 tttaccgtaa gctgtgtcct tactctacca atggatacag aatgttatga aggacatttt
     4441 gtctgtttat gaaggacatt ttgtctgttt atgaaggaca ttttgtctgt ttatgaagga
     4501 cattttgtct gtttgaacgt caaatatgaa tgtcttgaca tttaaaaaat gtcattcata
     4561 attggattga ggtgattata tggctaatga gattgtaaaa taccaccatg aattaaatac
     4621 aattccttta agaaaattta caccggttga aatgaatttg tttttttcca tcgtgtctag
     4681 aatgcgtgaa aaaggggata agacagttcg ttttacgttt gaccaactaa aagatttaag
     4741 taactacaaa gcaactgcaa atgtacgatt tgtagaagat ttaaaagcaa cttatgaaaa
     4801 aatcttatct ttacgctttg gtcgtagaag tgagtctggg ctttcttacg atatgtttgt
     4861 aatgtttaca gaatttaaaa tcaacgggga cgtagaaaat ccttacgtag atatacgaat
     4921 ttacgaaaaa gcactgcctt tgttaaataa tttagacgag tgggtacgct attctttaca
     4981 acaattcaac gagctacaaa gtggctatgc aaagactatg tttcgtctgt taaagcaata
     5041 cagaaccaaa ggtttcgcat atttctccaa agaagacttt cttgaattat tagatattcc
     5101 taaaagttat aagcaacctg atatagataa acgagttata aaacctatac gtcaagaact
     5161 aactgcaatc ttcaaaggac taacaatcaa aaagaaatac ggaaaaggac ggggaaaacc
     5221 tgttattggc tatcaattta cgttcaaacc tgagatcaaa aaagcagacg actttaacaa
     5281 acatgcacca accaaagaag accaaaataa agcattggct ttagctgata aacaaaaaga
     5341 atacgaagaa cccgctacaa caattaacga aaaaatcaaa cagaagaaac gagaacttga
     5401 actcctccaa caaatcaaac aactagaaaa agagaaaaaa gctcttgaaa aacaaacaga
     5461 gtccgcactt tcggaaaaag agaaaaaaag tttattatct gatttagata atttattcca
     5521 gtagcaacct aggaggcaac cagtatgcaa ccacaagaaa cctttacaat aaaggaattg
     5581 tcagatcttt ttaagatgag taggcaagca atatcgaaac atatccaaaa attagattct
     5641 tccatgatag ctaaaaatga gcgtggttat aaggttgtat tgcgttctgg agtattgcaa
     5701 cttgctcgca acttagacaa tcaaaggttg ctagataagt tgcataaaca tgaacaaaac
     5761 aacgataaaa atgcttatat accaaacaaa aacgtggttg caaacaagtt gctagatcag
     5821 ttgcgtgaag aaaatgaatt tttacgagaa caacttgccc tcaaagagca aaataattct
     5881 aatatgcaaa aattactcga ccagcaacaa cagctcaccc tacaggcaaa tcaacagatc
     5941 gaaaaattgc aagaacagtt acaattagct tatacggaag aaactccaga agatgaatca
     6001 actcctattc tttctgaaga aacagaatcg atagaaaaac acacaaaaaa gaagcaaaaa
     6061 tggtggcaac tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc
     6121 ggttctattt tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa
     6181 gggaataaac atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa
     6241 ttgtttgtaa aagaaacgga taaataataa aaaagactgc tttttcgagc agccagttaa
     6301 aaaaataatg agagtttatt cttgaaaaag cagcgcactt ataaagcgct accaaaaatt
     6361 tatcatattt tatgaaaaat aacaacccag taaaaaatga ctggtaaaaa ttcacaaaga
     6421 aacggaaaga agcaactgca gaaaatcaag ccttaaaaag agctttttac ctagaccaat
     6481 ccaaaatcac aaagtgagcc cctgtatcgg ttgatacaag ggctacttgg catactgtac
     6541 attatgttaa ctagctcgat aaataacgat tatgttccca aaacaatatt ttatgaacta
     6601 taacaaaaat ttgttatcgc atattgtata ttttaattat ataattatag gtgtatacca
     6661 cttaaattta acacaaagac gtgattattt tgaaacccaa aaagaaaatt tatctaggtc
     6721 tcctcttttc cttgatgatt ggaattttta gtataggaat tacaaatacc tatgcttcag
     6781 aaaattctaa tttcaatatc aactcccaac caattgaaga acaagcaatt aattttgcga
     6841 aaactgattt tgaacactcc ataacttcaa ttcttttaat ggaaaataac accgaaactg
     6901 atattaacta tactcttggt tcgccattta aaatgctcga tggagaaaat acggcaaata
     6961 gttctatttt ctttccagta ttttcagacg ctgataatac gattaaatat atttataccg
     7021 tc
//
LOCUS       DAIGUC010000094         6758 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.097, whole genome shotgun sequence.
ACCESSION   DAIGUC010000094 DAIGUC010000000
VERSION     DAIGUC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.097"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(193..1104)
                     /locus_tag="NOB46_002635"
     CDS             complement(193..1104)
                     /locus_tag="NOB46_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI1059535.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1561..1989)
                     /locus_tag="NOB46_002636"
     CDS             complement(1561..1989)
                     /locus_tag="NOB46_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059536.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(2017..2655)
                     /locus_tag="NOB46_002637"
     CDS             complement(2017..2655)
                     /locus_tag="NOB46_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059537.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(2659..4641)
                     /locus_tag="NOB46_002638"
     CDS             complement(2659..4641)
                     /locus_tag="NOB46_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCI1059538.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4821..5486
                     /locus_tag="NOB46_002639"
     CDS             4821..5486
                     /locus_tag="NOB46_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059539.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT         2178 a         1231 c         1021 g         2328 t
ORIGIN      
        1 tgatattgtt ttctttattt aagattatac agaaaaatat ctagggtcgc tggattctaa
       61 gtaaaaaaaa tttttaaaat aaaaagaact aaatcaagta gtaattaaac tactgttgat
      121 ttagttctaa taaaaagatt tagatgaaca gttttattga tttaaatagt tcatattttt
      181 tatttatacc gcttatttac tacttgctgt actagaatct gaagtgaatg tactcaaaac
      241 attttcaaag tctttgtctt tgatttttac attagcgtct ttcaatactt cgccaattac
      301 tttattctgg aaggtactgt cacttaattt tgtgtctgtt gcaatttctt tcaattcttt
      361 tttgtattta tccatgtcgt tgcctttgtt ttggtttttc accattttaa ccacataata
      421 ttccgtagta taagttgaag cattggtaga agtgatcaca tcagaaactt gaccatcttt
      481 caacttaaag gctgcttctt tgacttctgc cggaaccgtt gtagtagtgg aatcaaattt
      541 cacttttccg ccatcttctt ttgtcgtagt atcagttgac ttgtctttgg ctaatttaga
      601 gaaatcgtct cccttatcag cagctttctt cacatctttt gcatcatctt cacttgctac
      661 ttggataatt tgagcttcca cttctggatg gaaagattcc caagccgttt ttaaatcttc
      721 atcggtcaat ttgatatgtt tctttagacc ttcttgaaag gctagacttt gtttgatact
      781 gtctttgaat gtttgttctg tgtaacctgc agatttcaat tgtgaatcaa atgaatcacc
      841 caattgtttc tttgtttgat catattgaga atcgatttct ttggttgata cgtcatctcc
      901 atatttatct tcaaatactt gataaacgat caactgttgc acagcggaat ctgctccttg
      961 catttttttc aagctatcca ttacttcttg ttcgctgatt gtaccgcctt tataactaac
     1021 ggctgttttt tcaccggcat tcgtacagcc tgacaataag ccagtgccta gtacgatggc
     1081 aagtgctaaa aatctttttt tcatttatca attctcctac ttttcgtttt ttgcgaattg
     1141 ctaaaaacaa aggtgttcaa gatgaaaatc atcaagaaca cctttactaa tctgctcgat
     1201 acgtcctgaa tagatataag gctacacaat ccagaaagtt cgctcagcag aataaatgtc
     1261 aagtagcaca tcacacctta atatactact tcttttgtta ccgtttttca agtctatctt
     1321 gcgttccgta tttaacgtaa ctaattctta gaacaaatgt tatcgatttt gtttttcttc
     1381 ttccgctgct gggatattca aatcagacac ttttatgttc gattttccag acattttttt
     1441 gttgttttta ttatgatata tttttataca actaaaaatg aatatattaa aactaccaaa
     1501 aataactttt aacgctgttt cattatatgt tttttctatt ttatataaac ttttggatac
     1561 ttaataccaa ccggttggat tgtaccaaca tgagaatgtg tcagttctat ttcctgtcgc
     1621 acttgcatag gcccatactc cttttgttgc atttgctgat cgaatagagt ttccaacttt
     1681 cgcttttgca ccgtgacgat tatagacacg actatagtgg ttagaatgac ctgtttttct
     1741 cgtacaagtt gtatcactat aataaaccca tcttccagag ctatgattaa ttgctgttct
     1801 agaaatttcc cggtctactg gtaaatttga cttaataata ttacctttag catcaaaatg
     1861 aatctctcct ggctttaaag atttgtaata gatttcaccg tgaactgaat ttgcttccac
     1921 ttcagatgac atagcgtttc ctccaacaaa acctatccct agtgcacaaa taataactgc
     1981 ttttttcata aaacgacatc ctttcctttt tgatttttaa agcatgatct tcttgtttcc
     2041 tattttggtc agatatggat catgcgtgac tacgataact aacgtacctt gggaagcttg
     2101 ttgcgataag atttcaacta ctttatcctt atttctttta tccaatgacc cagtcggttc
     2161 atcggctaaa atgattttgc tattcttcaa taagactctc gcacaggcga ttctttgctt
     2221 ctcaccacca gataatgtgt agataggcgt acttagcttc ttgtttatat ttactttttt
     2281 caatgcctca tactttgctg ttcgcttatc tgaaacattt aaattcgaaa acttcaatcc
     2341 aatatctaaa ttaaaatcga ttgtttcata ttcaatcaac ccaaaatctt gaaaaagaaa
     2401 agatatggta tttcttttta tcaagcgctt ctctctccca gttaattgtt tcgtctcttg
     2461 atcgaacaaa tagaattgtc ctgaactgaa ctgatcattc aatcctaata tattcaataa
     2521 cgtactttta cctgctccac tttctccaac aacagtcaca agatccccag catccgcagt
     2581 gaaacgatcc aaatgaagaa tcgttttgtt tcgaatgatt tttttcgcac cttttatcac
     2641 tatcaacggc tccaattgtt aacctccatt catcagcaat aactgacttt tcttttctgt
     2701 agacaaaata aaaacaactg aaagaataaa atcaatgaag ctaaagaaaa aaatattaaa
     2761 aagatattta ggctctcttt ctataagaaa aaggaagatt acacttgtcg ttccccattt
     2821 gatgaggttc atcatgaaga aatctttata cgtttcaaag agcgaataac cacttgaacg
     2881 aaagatagcg attttccgac aattgtagac aaaatatatg cataacatga catagctcaa
     2941 caagaagaaa gaaaagaaag tgagtaaaaa tatctgtatc aagtaatgaa atgatctgct
     3001 taacactttg acagctatct cttcagtctg agtatacgga aatgataact gcaagttatc
     3061 acgtaactga ctttcttcaa tcagctcaaa taacctttct ttcgacaaag agcctatctt
     3121 gatctttaac ggtggataga tttctccgct gagaatattt ctttccaaat acatactgtt
     3181 tttcaatgtc agtatttcaa caaccggata atgttcgatc caggggatag aaggaataaa
     3241 tgtataaatg ggttgattgt tttttataaa tagaaatttc ggttcttttt cactgatttc
     3301 ttgataatat tctgttattt gcgccaggtc attttttaaa tctgtatgtc tatatcgttc
     3361 agggatcaat ataacagggt gcgtttcttt ttcggttatt tggatcaacc ttccagagac
     3421 atcaatcaaa ggaaatttct taagataatt cagatttatt tttatccctc tgccaaactg
     3481 ttcattttct tcattcaagt aatctgatac attgactaat atacttccgt ttttattcaa
     3541 agtttcatat aattcctgat ctgctgctga tgcaaaacga ttggaataaa taaaatccac
     3601 gtggtttttc ccgatggtta ctggataaaa tacatgatag tcctcaccag cgatttcttt
     3661 tggtggttca tgggaaacag ctaactgtga agaagaaaaa acgatagttg ctaattcgac
     3721 attggcaacg gtcaaaagaa gagaaaacaa caatccaaat gtaaaaagaa tgtattggat
     3781 atagttgaac gcttctctta acgaagcgat tttttcaact aataaaagag aaatcaaaga
     3841 gataccatat attccgctga acaagaaaac gtacatctgg aacaaataaa gaaattgctc
     3901 cttataatac ataaaaataa aaccaccaat gattcctgca attatgaatg taataatgat
     3961 tttctttttc cccaataaac accacaatac ttgatgtaat gaaaagtcat tattcaacaa
     4021 taaactgatt tctttattca tcaataagaa aaaggatgat aacaaaagga ataaaagaat
     4081 caatccaata gttaaataca ctcgataatt atatacgtct gtatttgaaa taaccgaata
     4141 cgaatagcta ttttcaaagt cttcaaaaat attagtggca taatcagtgt gaaatgcttg
     4201 attgaatcga tcagtgaata gtgaaatgaa ccgttcatag gcttcttttt ctctcgtcat
     4261 caagaaaaat tcaccttcaa aatcttttat tttgatcgat tcttcaatgg acgttacgcg
     4321 aaaggaggta ttagaatagg gtaccttctc gtgagaagat ttgacatccc cttgataata
     4381 caatgtcatt tcaagctttg gctgtatctt gaagttccaa gatgtatcta cttcattgga
     4441 ttcatttact gtttttttca tataagaaag ctcagtttct gatgagacat tttcaaatac
     4501 catgattagc tgctcatatt cttcttgccc aataaaatgt tgtggcaatc gaatcggagt
     4561 ataagtatct gtttgatgga aaaattcatt tgtccgatag agtacctgtt tatttatact
     4621 aaccaaggca aaaccactca tgataccggt cactatgatt gtgagtaaaa ctgtgaactt
     4681 ttttttgatt atcaccactc tcccttactt aaatgattct ttgataaaat cataccgttt
     4741 ttcatcaaaa aaacgtatct atcaagtgta taggtcatgt agaataaatc tatatactgt
     4801 agaatcgaaa ggagaagaag atgaacaccg gagaaaaaat acgaacttac cgcagaaatt
     4861 gtaagcttac gcaaaaagaa ttaggcgaaa aaattggtgt ttccgataaa acgatttcta
     4921 gttgggaaaa ttctcgtaca atgccagacc ttgaaatgct gtcactttta catcatactt
     4981 taggtctgcc gattgatttt ccttctattg aatcagctac cgaatcaata gaaccaacat
     5041 tgccagatga acctcttgtt aacaagaaat cttattcatc aaaacaaccc ttctcactca
     5101 aaaagacact atctttcttt ctgctcgtct tttgtttggt ctatcttttt cttatcaatt
     5161 atcaatacaa aaatgaaacg atcgatcgat tcaatccttt tttgaaacca caaatcggct
     5221 ataccacact ccctgtagga tacgtggaca attccatcga acgttgggta tgtaatgata
     5281 tctttggcca tggtacatgg ctgtcttttc acgctggaga ggtagaaaaa gagaaaaacc
     5341 atgctgtaat caaacacaaa ggaaaacacg tcatgaacgt tcgcctgctc acttgggaag
     5401 ccattccctc agattaccaa gaaatcctca gccaagacta tgacgacgcc ttaaaaagaa
     5461 gccctcagga gccagatagg cattaagtag gagatgaacg tagagataga aaaaatcaat
     5521 gcacatgatc ttatccaaaa aacaggggta caaattaatt gaaaaagcct tgagatgaaa
     5581 gttcctaaat aaaaaagttc agaatgatag gtatttctgg cttatagtat aatatttacg
     5641 ccacagcctc ccaatgattc tttttggaat cataatcaag gatggacatt cacaaaaata
     5701 ttttgctcat tcgatccgaa tagattaacg accaatctag taagtaatat agattggtac
     5761 gtagtcaagc tgcacataat ttagatcaat tttagttctt ttttatattt ctatgatctg
     5821 ctcatttact tttatatgat ggcttacagt aacataaata aatatgataa tcgctggtag
     5881 tttatccaag agtactcaat aaaatacaaa atggattgtt caagcgccta tcataatgat
     5941 aaaatgaaac aaataaacga tacaaggagg aagagacttt gagtaatggc agaacaattt
     6001 tttcattgta aaaattgttc agttgttaat ctatgggatt tcggtagcat gggcattttt
     6061 ttatagagga atcacaccaa cctggccgtt ttatctcttg ttagtgggaa tattagtagg
     6121 aaattttgcc cctcttcact atcgtacgaa cttttttcca actgattctg gcctttttct
     6181 taaaacaaag acgcgaaaat tagaaaacat tattgaaatg acaattacct gtataatcat
     6241 tttcttagtt atattcctaa acgtcttcta ataagaatct cttaaaatta gcttgttaca
     6301 gttagttacc tagtttatat aacacagtta tcttatcttc cttatcaaca tcttttgcca
     6361 actctttgtc ttaaattcga aacatataag cagagctacg aacaccaaga ctgtttcggc
     6421 tctgtttttt gcatcaaatt cactcttata tagctgataa tctcggctct ttaaaagaaa
     6481 ttattttcgc ttcattttat tataaaaagg ctaggaacct tgatgttatc aggttcctag
     6541 cctttattta agtattaccc cacagaccct tccatataga tttttaaatt acacactagt
     6601 ttaaactaaa acaaacaagg aaacacttac catttaatca taaaattagc tcatatgaat
     6661 atattagaat gtaaaataga ctggtcaaaa tctggtcaaa aaagaggact aatacaggta
     6721 gtcctcagac tgtagacaaa gtccatttta tggatgat
//
LOCUS       DAIGUC010000095         6557 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.098, whole genome shotgun sequence.
ACCESSION   DAIGUC010000095 DAIGUC010000000
VERSION     DAIGUC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.098"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            122..1393
                     /locus_tag="NOB46_002640"
     CDS             122..1393
                     /locus_tag="NOB46_002640"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI1059540.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            1390..2685
                     /gene="rho"
                     /locus_tag="NOB46_002641"
     CDS             1390..2685
                     /gene="rho"
                     /locus_tag="NOB46_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCI1059541.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            2784..3047
                     /locus_tag="NOB46_002642"
     CDS             2784..3047
                     /locus_tag="NOB46_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCI1059542.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            3492..3941
                     /locus_tag="NOB46_002643"
     CDS             3492..3941
                     /locus_tag="NOB46_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1059543.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            3998..5416
                     /locus_tag="NOB46_002644"
     CDS             3998..5416
                     /locus_tag="NOB46_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1059544.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            5416..6276
                     /locus_tag="NOB46_002645"
     CDS             5416..6276
                     /locus_tag="NOB46_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCI1059545.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            6450..>6557
                     /locus_tag="NOB46_002646"
     CDS             6450..>6557
                     /locus_tag="NOB46_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCI1059546.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEA"
BASE COUNT         2173 a         1156 c         1454 g         1774 t
ORIGIN      
        1 tttgaagtcg ctctccattc ttttttactt aaaacggcag accatgctcg tttctttttt
       61 ttatctatga taaaatacaa gcatatccat gaaaaaagat taataaacaa ggtggaaaca
      121 gatgaaaaaa atcgtaatca aaggaaaccg acctttagct ggtgaagtaa cgatcagcgg
      181 tgcaaaaaat agtgcagtcg cattgattcc agctgcaatc ttagctgatt ccccagtgat
      241 cttggaaggt gtgccggaca tacaagatgt tcattcatta attgaaattt tagagatcat
      301 gggcgcaact gtccattttt ccaacaacat actagaaatc gatcctcgag aagtcgtatc
      361 gattccgatg ccgcacggaa aaatcaatag tttgcgtgct tcttattatt ttatgggaac
      421 actgcttggt aaatttggcg aagcggtagt aggcctgcca ggtggctgtt atttaggccc
      481 tagaccgatt gacctacacg tcaaaggatt tgaagctcta ggtgctgaag tgacaaatga
      541 acatggtgcc atgtatttac ggacagaaaa taaaggattg cgtggcaatc ggattttcat
      601 ggacgtggtt tcagtcggag caacgatcaa tgtgatgtta gctgctgtaa aagcaaaagg
      661 acagacagta attgaaaacg ctgcacgaga accggaaatc atagatgtgg caactttact
      721 gaataatatg ggggcaaaag ttcgaggagc gggtacagat gtgatccgta tcgaaggagt
      781 cgaaacatta catggctgtc ggcatttcat gattcctgac cgcatcgaag caggaaccta
      841 tctagcatta gcagctgcag taggaaatgg tatcaaagtg aaaaatgtga tctttgaaca
      901 tttggaaagc tttatagcaa aattgcagga aattggtgtc catatgaaaa tcagcgaaga
      961 tgaaatcgaa gtttacccct cgaaagaatt aaaacccgca aacatcatga cctatcctta
     1021 tccaggattt gccacagatc tgcagcagcc acttactgcg ttactattga tgactacagg
     1081 cacttcagaa atcatcgata cgatctatgc gaaacgtgtg aaccatgtgc cggaactagc
     1141 acgaatgggc gctgatatta ccgtggaagg aaatatgatc atcgtgaatg gtccaaataa
     1201 acttcacggc acagaagtcg tggcttctga tcttcgggca ggtgcttgtt tagtgattgc
     1261 tggactattg gcagaaggga caacgacgat ttacaatgta gattatatct tacgcggtta
     1321 tgatcatatt atcgagaaac taacagcctt aggggcatca attgaaatga tagaggaagt
     1381 gggagctgaa tgagcgatta tttgacaatg gcagaactag agaacaaaac gttaaaagaa
     1441 gtttatagtt atgccaaaga atttaaaatt ccttattaca gtaagatgaa taaaaaggaa
     1501 ttatctctag ctgtgattcg tgcacaagca gagaaacaag gattttatta tatggaagga
     1561 atattggata tcgttggtca agatggttac ggttttttac ggccaatcaa ttatggacca
     1621 agtgcagaag atatctatat ttctgcctca caaatcagac gattcagttt gagaaatggg
     1681 gacaaagtgg caggaaaagc ccgtccacct aaagaatcgg aacgttatta tggtttgatg
     1741 cacgtggaaa gcgttaatgg aaaagatccg gaagaagcaa aagaacgtcc gcattttcca
     1801 gccttaacac ctctttatcc gcaaagacag cttcaactgg aaacaacacc gcaaagacta
     1861 tctacccgaa tgatcgatat cttttctcca atcggttttg gtcagcgtgg attgatcgtc
     1921 gcaccgccaa aagcagggaa aacttctgta ttaaaagaaa tcgcaaatgg tatcaccgaa
     1981 aactatccgg aagtagaatt aatcgttcta ctgattgatg aacgaccgga agaagtaacg
     2041 gatctagaac gaagcgtgaa aggcgacgtg gtatcttcta catttgatct gcagccgcaa
     2101 aaccatactc gagtttctga attagtattg gaacgcgcaa tgcgtttagt cgaagataaa
     2161 cgagatgtcg ttatcttgat ggatagtatt actagacttg ctcgggccta taacttagtc
     2221 gttccaccaa gcggacgtac attgagtggc gggattgacc cagccgcatt gtataaacct
     2281 aagaaatttt tcggggcagc aagaaacatc gaagaaggtg gcagtttgac gattttagcg
     2341 accgctttag tcgatacagg aagccgtatg gatgacgtga tctatgaaga attcaaagga
     2401 actggaaatc tagaattaca actttcacgt gaattatctg aacgtcggat cttcccagcc
     2461 atcgatatca aaaaatcagg tacccgaaaa gaagaattat tgatgccaag tgaagaatta
     2521 gaagaaattt ggaaacttcg aaaaaatatg actggagatt cattagaata tacggaacaa
     2581 ctgatccgct ttttgcgtaa aacaaaaaac aatcagcaat ttttcaaaga atttcaagat
     2641 gtctcctttg gtaaaaaaaa tccgaccaga aatctgaaaa gataattgca accttgactg
     2701 aaacatgtta agatgttaat gttgtaaatc gacaaatcaa ctctggttca gcaaatggag
     2761 cagggcaaag gagcgaaaaa atcatgaaag aaaacatcca tccagattac cacccagtag
     2821 tattcatgga ttcaacaact ggtttcaaat tcttgtcagg ttcaacaaaa acttcacaag
     2881 aaacagttga atgggaagac ggtaatacat acccagtcat ccgtgtcgaa gtaacttctg
     2941 actcacatcc attctacact ggacgtcaaa aattcacaca agcagacgga cgtgtggacc
     3001 gtttcaacaa aaaatacggt ctcaaagacg caaacgctgc ggaataataa aaacgctgat
     3061 aactcaacgt ttagcagact atctgatagg gatagtctgt ttttttatgt tttttgccaa
     3121 tttaaaactt cgtttgatgc tgaaaaagtc gtaggatcat aatgcacaaa acaatgaaaa
     3181 actagtatat agttttaatt atccacttga taaaaacacc ttatattaac gaaatgaaga
     3241 ggggttattt cgaagtaaaa aaccatttac ctaaaattag aagctaagct ttcctttcaa
     3301 ggaaggcttt ttgttttgtt atagacttgc gattgtttgt gagctagatc gttcatttta
     3361 atgacttata cacgcggatg atgggtcttt ttcctctgtt cattcataat attgaacggt
     3421 acagctagcg atgctatact gacctcagtt ccaagaaaac gttaacattt tttgtggggg
     3481 agaggttttt tatgaggttt gatcaattga tcgcagaaga actgattgtt ttcgatccat
     3541 cgatagattc aaaaggatca ttatttgagc gaatagggga tgtgttgaaa aaaacaaata
     3601 aggtaagaaa tgttcaaaaa gtcgttaagg cactattcaa acgagaggag gagatctcca
     3661 caggaataga agatggattt gggattcccc atgcaaaaag caaatatgtg acaaaaccag
     3721 cactgtgttt ttttcataca gccaaattaa cggactatag cgggatagat gaaatgccaa
     3781 ttgaatatat ttttgccatc gtagttcctg aaaaatcagc agatatgcat ctagagattc
     3841 tcagcacact ctccagacga ttgatgaatg cagattttag aaagggaata aaagaagcca
     3901 ctacgccagc agatatcatc agacagatta gtcaagaatg aaaatagtag agtctttgtc
     3961 cgagtatcga tagtgaagaa aaaggaggaa aataatcatg aaaatcgttg gtgtaactgc
     4021 ttgcccgact ggaattgctc atacttatat gtcggcagaa aaattagaag taacagcaag
     4081 aaatctaaac catcaagcaa aattcgaaac acaaggtgta aaaacagaaa atcagttatc
     4141 tgaacaagaa atcaaagagg cagatgcaat cattcttgca gtagataaag aaatcgaatt
     4201 ggaccgattt gccgggaaaa aagtaaagcg tgtctctaca agccgagcaa tcaaagaacc
     4261 gcaagtagta atagacgaag cattgagaga tattggcgta ttcgttgtgt ctaatgaaaa
     4321 agaaccagct gcaaatgaga aaaagccgac aatctataat catttcatga atggtgtgaa
     4381 ttacatgctt ccatttgtga tcgcaggcgg aatcatcatc gcactgagtt ttgcctttgg
     4441 gattacagcg gctgatccca actcagcaga ctataatgtg ttagcagctg cattttcaag
     4501 gatcggagga gatacagcgt ttgccatgat ggttcctgcg ttaggcgcgg ggattgctac
     4561 atcgattgct ggaaaagcag gttttgcccc aggaattgtt gccggattac tggcctctac
     4621 aggtggttca ggttttcttg gcggaatgat tggtggcgtg ctagcagggt atatctgtga
     4681 ttttctggca aataaaatta gcgtaaaaaa agaattttct gctatttatc agctgattgt
     4741 cgtccccttt ttatcgatct taattattgg gcttttgatg gtatttgtga ttgaacaacc
     4801 gatcacatgg gtgttggatg ctttgacaaa ttggctgaat agcttgggaa atacatccgg
     4861 gctattgttc ggattactta tcgggatcat gatggcagct gatatgggtg ggccgatcaa
     4921 taaatcgact tcgactttct cgatcggttt gatgtcagct ggagtaaatg caccgattgc
     4981 tgcttgtatg gctgcaggaa tgacacctcc cctaggtatt gctttagcca ctttattatt
     5041 caaacataaa tttaccaaag aagaacggac ttcaggtcaa tcatgctgga ttttaggcgc
     5101 ttcgtatatt acagaaggtg ctataccgtt tgcggtatct gacccgatcc gcgtgatacc
     5161 tagtttgatg acaggttcag cagtcgctgc agggatttcc atggcagtag gagttacttc
     5221 aatggcacct catggaggga tttgggtgat gctaattcca aatgttatga acaatttacc
     5281 tatgtatgtc ttggcaattg catcaggtac agtcactaca gcctttatgc ttggactatt
     5341 gaaaaaaaca gtgaaagaga aaaaacaaga caagtggacg aaaaatgaaa atctaacaaa
     5401 tgaggtggaa gcgtaatgtt atatacaatg aaagagttat tgaaagtggc taaagagaat
     5461 caatttgcag taccagcctt caatatttgc agctatgata tgatgaaagc aatcatcgaa
     5521 gaagcagaga gattagaagc accagtaatc ttagaaattc atcctgatga aatcgcctat
     5581 ttaagtgatg agtttgttgc ggcagtaaga gcctatgctt atacaagtaa actgccgatc
     5641 gttatccact tggatcatgg cggtacgata gaagatgtct tacgggcgat tcgaaacggc
     5701 tattcttccg tgatgatcga tgcgtctttg aaatcattcg acgacaatgt acagattacg
     5761 aaaaaagtgg ttgcgttagc tcatgcggta aatgtctcag tggaggctga gcttggaacg
     5821 attgggaata atggttctgc tgaaggaggt gctgaaacaa tcatttatac agatcctgat
     5881 caagcgaaga tttttgtgaa agaaacagga atcgatacac ttgctgtagc aattggaaca
     5941 gcgcatggct tgtatccgaa aaacagaact ccaaaattaa atatcgactt actgaaagaa
     6001 ttgaaccaac aaatcgatct tccatttgtt ttacatggcg gttcaggtaa tccggacgca
     6061 gaagtcagcg aagcagtaaa atacggagtt gccaaagtga atttgagctc agatcttaaa
     6121 agcgtctttt tcaatgcttt gagagaaata ttgagtgaaa atccatcgat gtacgagccg
     6181 aatgcaattt atccagcagc taataaaaag gtacaagaag tggtcaaaca taaaatggaa
     6241 attttgaaca cagtaggcaa ggctagttta tactaaaaat aaaaatgtgt ggtcaagagg
     6301 gtatgacaat agtcttgtca taccctctta accacacacg atgttcagaa gtagtttttt
     6361 cgaaaaattt cttcttattt ctcgaagcca atcacttctg tcacaacctc ttttttcctg
     6421 ttactatata aagtaaatgg ggtgatttta tgttgaatga agtggagaat agacagcagg
     6481 agattgtgaa ttatctaaaa aacaaccaat ttgcaagagt caccgatttg atcgagttag
     6541 taaattatag cgaagcc
//
LOCUS       DAIGUC010000096         6486 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.099, whole genome shotgun sequence.
ACCESSION   DAIGUC010000096 DAIGUC010000000
VERSION     DAIGUC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.099"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            152..2095
                     /locus_tag="NOB46_002647"
     CDS             152..2095
                     /locus_tag="NOB46_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1059547.1"
                     /translation="MLSKRESQLIELLLEEENFQPASFFSEKLNVSNKTIYQDIQKLG
                     QFLNRFELKIEKKPRMGIYLIGTSTKKNDAKIFITSKEAMSTKVKYSSNYRRVYLFAN
                     LIFKTDKKRYEYFEKKFFVSIATLRKDYEEIIKYCRLAGIRITSNHVIDTQKTPEELI
                     QRTFVNYFEKNIGVGNEKCQYHFVFDQAMVKFVDDFVKNFYQQSKQQPTNYIVHSLKL
                     SLLTLIGRVKHGYHSQTNKNPLFVEIKKMELYMVALDFSNGVKDELNCSFTINDLYFI
                     CSLFMGHGVRPFVNLATHSQQIMETTKQFIQDMSTLVEKDLGQDSQLLQSLFAHIEPM
                     VYRLQMGITIKNPLKEDIIRQYSTMYTLATYCIPKLEKAMGIRVTDDEITFLTIHFQL
                     AFEKIVNTKHVFLICPTGLGTSQLLFQRIRHSSPSTVVYEVIDVQKLQDYNLDSVDLI
                     ISTVKLENEYQTPVIYVRPLPTKEEIALINRHLLTLNQQDNTFLPSIAPDKTILKKYL
                     KDGWMFLNQDFDSRESVLSFITEKYKEEQLVKDNFLEVVLQREKLGATGLSSGVAIPH
                     ANPKYVVKTKISIITLKNKITWGDVDIRVVLFLAIAEEDMIQVKNMIALLYDVFVSPE
                     RIKSIASKETRNEIINEIIGKRK"
     gene            2097..2558
                     /locus_tag="NOB46_002648"
     CDS             2097..2558
                     /locus_tag="NOB46_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI1059548.1"
                     /translation="MTSYFGKKIALFQSEVKSQKEALSIIATCLYQTGLVKDSFAENV
                     LKREEVFPTGLLINDVGIAIPHTDAEHVNDSQIAFMSLKTPVTFYEMGTADKEISVSL
                     IFMLALKEPHAQLEMLQKLITMFQKKEVVQKLRAVNNTEEYYQIIEKEGFV"
     gene            2582..3928
                     /locus_tag="NOB46_002649"
     CDS             2582..3928
                     /locus_tag="NOB46_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI1059549.1"
                     /translation="MLDLLQKFVDLGSIVVLPILIFVFGLILGTKPSKAFISALTVGV
                     GFVGLNLVIDLLTNSLGPAAQAMVERFGLNLTTIDVGWPAAAAISYGTVLGSLAIPVA
                     IVVNVLLIIVGLTKTLNVDIWNIWHAAFVASLVYAVTNDFAMGMLATVIYTMMILLFG
                     DILGPIINKFYGFPNITFPHGTSAPGFVFALPLNWLFDRIPGLKDWHADPETIQKRFG
                     IFGDSTVMGFLIGLVMGILAGYDVAGIGQLAVKTGAVMVLMPKMVALLMEGLTPISES
                     ANSFVQKRFPGRELYIGMDAALSVGHPAVLSSSLILVPITILLAVILPGNTTLPFGDL
                     ATIPFLICLMAAVFGGNIIRTILGGTIYMVTILYITSWVAPFLTKAAQGANFDLQGHS
                     SVTAMAEGGLWTTLLYVGGAKLFGYFALVGIGLIITGLLFYVNRILPKRAAKQTEA"
     gene            3951..4235
                     /locus_tag="NOB46_002650"
     CDS             3951..4235
                     /locus_tag="NOB46_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1059550.1"
                     /translation="MKKLLIMCGTGVATSTVVTGKVKEWLKSKGLENEVKLYQSKVAD
                     EIGKIDDYDIVVSTTVVPDNIKDKVIMGLPLLTGIGIDGLFDEIEAKIKA"
     gene            4262..5089
                     /locus_tag="NOB46_002651"
     CDS             4262..5089
                     /locus_tag="NOB46_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HCI1059551.1"
                     /translation="MLVTTKEMFEKAQKENYAIPAANFFDLDSARTFVEVAEKMQKPL
                     ILAFAQAHIEECPLEEAALIATYLAKKASVPVALHLDHGQDEEIIKQAIELGFTSVMI
                     DASQDEIETNIRRSKAIAEYAHERGVVVEAEIGHVGTGNSYEFKETTDTIYTEVEEAA
                     RFAKETGVDSLAVSIGTAHGQYKGTPKISFERLEEIKNEVSIPLVLHGGSSSGDENLH
                     KCAVSGINKINIFTDFITAAMDVINEEKPEDYFTLKRLANQAIADTLSHYYEVFATK"
     gene            5102..5797
                     /locus_tag="NOB46_002652"
     CDS             5102..5797
                     /locus_tag="NOB46_002652"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI1059552.1"
                     /translation="MRTVRKPFFVVNPKSYLYGEQALKLAKTADQLAAAYDIDIIFTC
                     QHVDVRLIKEQTTQLIVSVQHIDGIVPGRGMGHVLPEGVVAAGAEATFLNHAERPLSV
                     SELCDAVKRAKELGLLTIVCANSLEEAKLVASLKPDVMVCEPTELIGTGQASDISYMI
                     QTNEAVRKMDPEIFVLQAAGISTVADVRKALDSGADATGGTSGIVCAKDPVDTLKAMI
                     EEVSKWKKEQSTK"
     gene            5794..6309
                     /locus_tag="NOB46_002653"
     CDS             5794..6309
                     /locus_tag="NOB46_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016380999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HCI1059553.1"
                     /translation="MITYTEQLVLTSNGQRVTYHNITEQVKEIVAKSGIKNGICLVQS
                     PHTTCSVIFEEFMHDLDFNGDEFLQVDLNRILDRIIPRELTENTDYRYPGPKHLDFLL
                     SLDDPDYAGDAGTILNGDAHIRASFFGASENFIVKEEILMTGTVGSIYFIDFDQNRVR
                     NRKCHILVMGE"
BASE COUNT         2149 a          986 c         1375 g         1976 t
ORIGIN      
        1 ttaaaaaaat tgtcgtgagt tttactgaca tcaaaaagta tagggtcata ataatctgtt
       61 ccacattaat gtggaacaga ttacgtattg atctttagtg agaaaaactc tatgatatag
      121 acaaggaaaa cgttttctga ggtgatgatg gatgttatca aagcgcgaga gtcagttaat
      181 tgaattactt ttagaggagg agaattttca accagcaagt ttctttagtg aaaaactcaa
      241 tgtttcgaat aaaacaattt atcaagatat tcagaagctg ggacagttcc tgaatcgttt
      301 tgagttaaaa attgaaaaaa aacctcgcat ggggatttac ttaattggaa cgtcaactaa
      361 aaaaaatgat gccaaaatat ttatcactag taaagaagct atgtcaacaa aggtaaagta
      421 tagttcaaat tatcgtagag tgtacttatt cgccaatcta atttttaaaa cggataaaaa
      481 aagatatgag tattttgaaa aaaagttttt tgtcagtatt gcaactttgc gtaaggacta
      541 tgaagaaatc atcaaatatt gtcggttagc tgggattagg attacttcaa atcatgtaat
      601 agacacacaa aaaacacctg aagagttgat ccagcggaca tttgttaatt attttgaaaa
      661 aaacatcggt gtagggaatg aaaagtgtca atatcacttt gtttttgatc aagcgatggt
      721 taagtttgtg gatgattttg taaaaaattt ttaccaacag tctaagcagc aaccaacaaa
      781 ttatattgtc cattcactca aactttcgtt gttgacgttg attggtcgag taaagcatgg
      841 ctaccattca caaacaaata aaaatccttt gtttgtcgaa ataaagaaaa tggaattata
      901 tatggtggca ctagattttt caaatggggt caaagatgaa ttgaattgtt cctttacgat
      961 aaatgatctt tactttattt gttcgttgtt tatgggacat ggagtgagac cgtttgtgaa
     1021 tctggcaacc catagtcaac aaatcatgga gaccaccaaa caattcattc aagatatgtc
     1081 gacactggtt gagaaggatt tggggcaaga tagtcagctg cttcaatctc tatttgccca
     1141 tattgagcca atggtttatc ggttgcaaat ggggattacc attaaaaatc ctttaaaaga
     1201 ggatatcatt cggcaataca gcacaatgta tacgctagca acttactgta ttccaaaatt
     1261 ggaaaaagca atggggatca gagtaacgga tgatgaaatt acttttttga ctattcattt
     1321 tcagttagct tttgaaaaaa ttgtgaatac gaagcatgtt tttcttattt gtccaacggg
     1381 gttgggaact tcgcaattat tatttcagcg tattcgtcat agttctccta gtaccgtagt
     1441 ctatgaagtg attgatgttc aaaagttgca ggattacaac ttagatagtg tcgatttgat
     1501 tatttcaaca gtcaaattag aaaatgagta tcaaacgccg gttatttatg ttcgaccatt
     1561 accaacgaaa gaagaaattg cattgattaa tcgtcatctt cttaccttga atcaacaaga
     1621 caatacattt ttaccatcca ttgcaccgga taaaacgatt ttaaagaaat atttgaagga
     1681 tggttggatg tttttgaatc aagattttga tagtagagaa tctgtacttt ctttcatcac
     1741 tgagaaatat aaagaagaac aattagtaaa ggataatttt cttgaggttg tacttcaaag
     1801 agaaaaacta ggagctaccg gactttcatc aggcgtagcc atcccacatg caaatcctaa
     1861 atatgtagtc aaaacaaaaa tttctattat cactctaaaa aacaaaatta cttggggaga
     1921 tgtggatata agggttgttt tattcttagc gattgcagaa gaagatatga ttcaagtgaa
     1981 aaatatgatt gcactacttt atgatgtctt tgtctcacct gagagaataa aaagtattgc
     2041 aagtaaagaa acaaggaatg agattattaa cgaaattata ggaaagagga agtaagatga
     2101 cgagttattt tggaaagaaa attgcattat ttcaatctga ggtaaagagt cagaaggaag
     2161 ctttatcaat tattgcaact tgtctatatc aaacaggttt agtgaaggat tcgtttgcag
     2221 agaatgtact gaaaagagaa gaagtgtttc ctactggctt attaatcaat gatgttggga
     2281 ttgctatacc acatacggat gcagaacacg tgaatgattc tcaaattgca tttatgtcat
     2341 tgaaaacacc agtaactttt tatgaaatgg gaactgcaga taaggaaatt tcagttagct
     2401 tgatcttcat gttggcgttg aaagaaccac atgcacagtt agaaatgtta cagaagttaa
     2461 ttacgatgtt tcaaaaaaaa gaggtggttc aaaagcttcg agctgtaaat aatactgagg
     2521 agtattatca aattattgaa aaagaaggat tcgtttaata accattttga gggggagcat
     2581 tatgttagat ttattacaaa aatttgttga tctcggatca atcgttgtat tgccaatctt
     2641 aatttttgtt tttggtttga ttttaggaac aaaaccgagt aaggctttta tttcagcatt
     2701 aacggttggt gttggatttg tcgggttgaa tttagttatc gatttattga ccaatagctt
     2761 aggaccagca gcacaagcga tggttgaacg ttttggacta aacttaacaa ccattgacgt
     2821 tggttggccg gcagcagctg cgatttctta tggaaccgtt ttaggtagtt tggcgattcc
     2881 agtagctatc gtagtcaatg tgttattaat tattgttggc ttaacaaaaa cactgaatgt
     2941 tgatatttgg aatatctggc atgcagcatt tgttgcttca cttgtctacg cagtaacgaa
     3001 tgactttgca atgggcatgt tggcaacggt tatttataca atgatgattt tattgtttgg
     3061 cgatatttta ggaccaatca tcaataaatt ctatggattt ccaaatatta ccttcccaca
     3121 cggaacatca gcacctgggt ttgtttttgc cttaccttta aattggttat tcgataggat
     3181 tccaggattg aaagattggc atgcagatcc agagacgatt caaaaacggt ttggcatctt
     3241 tggtgattca acagtcatgg gctttttaat tggtttggtt atgggaattt tagctggcta
     3301 tgatgttgcg ggaatcggtc aattagcggt gaaaactggt gctgtaatgg tcttaatgcc
     3361 taaaatggtg gcacttttaa tggaaggctt aacacctatt tcagaatcag caaattcatt
     3421 tgttcaaaaa cgtttcccag gaagagaatt atatatcgga atggatgccg cattgtcagt
     3481 aggacaccca gctgtattgt cttcttcgtt aatcttagtc ccaatcacga ttttattagc
     3541 agtgatttta ccaggtaaca caaccttgcc tttcggtgat ttggcaacta ttccattctt
     3601 aatttgtttg atggcagctg tctttggtgg aaacattatt cgaacaatct taggtgggac
     3661 gatctacatg gtcaccattt tatacatcac ttcatgggtg gcaccatttt taacaaaagc
     3721 agcacaaggg gcaaactttg atttacaagg acattcatca gtaactgcga tggcagaagg
     3781 tggactgtgg acaacacttc tatacgtggg tggtgcaaaa ctatttggtt actttgccct
     3841 agtcggaatt ggtctgatta ttacaggctt actattctac gtgaatcgca ttttacctaa
     3901 aagagcagct aaacaaactg aagcttaata caaaatagga gagatgacag atgaaaaaat
     3961 tattaattat gtgcggaaca ggtgtggcta cttcaacagt ggtaacagga aaagtaaaag
     4021 aatggttgaa atcaaaagga ctcgaaaatg aagtgaaact atatcaatca aaagttgctg
     4081 atgagattgg caaaattgat gactacgata ttgtggtcag tacgaccgtg gttcctgaca
     4141 acattaaaga taaagtaatt atggggcttc ctttattaac cggaattggc attgatgggt
     4201 tgtttgacga aattgaagcg aagattaaag cctaaaaaat acttgaaaag aaggtaatca
     4261 aatgttagtt acaacgaaag agatgtttga aaaagcgcaa aaagaaaact atgcgattcc
     4321 ggcagcaaac ttttttgatt tagattctgc aagaaccttt gtagaggttg cagaaaaaat
     4381 gcaaaagcca ttaattttag cctttgcaca agcgcatatt gaagaatgtc ctcttgaaga
     4441 ggcagcgtta attgcaacat atttagccaa aaaagcaagt gttccagtag cacttcattt
     4501 ggatcatgga caagatgagg aaatcatcaa gcaagcaatc gagcttgggt tcacttctgt
     4561 gatgatagat gcttcgcagg atgagattga aacaaatatt cgtcgttcaa aggcgattgc
     4621 ggaatatgct catgaaagag gcgttgtggt agaggctgag attggacacg tgggaacggg
     4681 aaatagttat gaatttaagg aaaccacgga caccatttat accgaagtgg aggaagcagc
     4741 acgttttgcg aaagaaaccg gcgtcgattc attggcagtt tcgataggta cggctcatgg
     4801 gcaatacaaa ggaacaccga aaatcagctt tgagcggttg gaagaaatta aaaatgaagt
     4861 ttcaattcca ttagtgttgc atgggggctc atcatctggt gatgaaaatc tccacaaatg
     4921 tgctgtttca gggatcaata aaattaatat ctttactgat tttatcacag cagcaatgga
     4981 tgtaattaac gaagaaaaac cagaggatta ttttacactt aaacgattag cgaaccaagc
     5041 gattgcggat acgttatcgc attattacga agtatttgca acaaaataga ggagggttct
     5101 catgagaaca gtaagaaaac cattttttgt ggttaatcct aaatcttatt tgtatggtga
     5161 acaggcattg aaactagcaa aaacagcgga tcaattagct gcagcatacg acatcgatat
     5221 catttttact tgtcaacatg ttgatgttcg gctaattaaa gaacagacaa cgcagttgat
     5281 tgtgagtgtt caacatatcg atgggatagt ccctggtaga gggatgggac acgttttacc
     5341 tgaaggcgtt gtagcggctg gagcagaagc gaccttcctt aatcacgcag aacgtccttt
     5401 atcggttagt gagctgtgcg atgccgtcaa gcgagcaaag gaacttggtc tattgactat
     5461 tgtttgtgca aattctttag aagaggctaa gctcgtagct tccttgaaac ctgatgtgat
     5521 ggtttgtgag cctacggaat taataggtac aggtcaagca agtgacattt cttatatgat
     5581 tcaaaccaat gaagctgtac gcaagatgga tcctgaaatt tttgttctgc aggcagcagg
     5641 gatttcaacg gtagcagatg ttcgcaaagc acttgattcg ggggctgatg caacgggtgg
     5701 aaccagcggg attgtttgtg ccaaagatcc tgtggacaca ttgaaagcga tgattgaaga
     5761 agtaagtaaa tggaaaaagg agcaatcgac aaaatgataa cttatactga gcaacttgtt
     5821 ttgacttcaa atggacagcg agtgacgtat cataatatta ccgaacaagt aaaagaaatt
     5881 gtggcaaaaa gtgggataaa aaatggcatt tgtcttgttc agtcgccaca tactacttgt
     5941 tcagttattt ttgaggaatt catgcacgat ttagatttta atggggatga atttttacag
     6001 gttgatttaa atcggattct tgatcgaatc attcctcgag aattaacgga aaataccgat
     6061 tatcgttatc ctggtccgaa gcatcttgat ttcttgctgt ccttagatga tccagattat
     6121 gctggtgatg ctggaacgat tttaaatgga gatgcacata tccgagcatc attcttcgga
     6181 gcaagtgaaa atttcattgt caaagaggaa atactaatga caggaactgt cggctccatt
     6241 tatttcattg attttgatca aaaccgtgtt agaaatcgaa aatgccatat tttagtaatg
     6301 ggtgaataga aaagtaataa gaaacaaaca tttgggaaac taattgaatg atcacaccta
     6361 taaaaattaa tacgaaagat aatagagtca agtccagact cctgtgtaaa atgctataca
     6421 atgtttttac catttctact tatcaaaatt gatgtatttt cttgaagaat aaatccattc
     6481 atcatg
//
LOCUS       DAIGUC010000097         5999 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.101, whole genome shotgun sequence.
ACCESSION   DAIGUC010000097 DAIGUC010000000
VERSION     DAIGUC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.101"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..797)
                     /locus_tag="NOB46_002654"
     CDS             complement(<1..797)
                     /locus_tag="NOB46_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1059554.1"
                     /translation="MTFAIYAYLKEKNNLFLWISLYLAFFIFDNTIIYMTEFLNSFAQ
                     SYDQVFMSAPAVKTIIFMGNAFFSISILAELQKEKLSPLHYALLLALAVWMITIPLMD
                     NSAFKVWLYYLGNQLFLFYLGIYCWRGTKKDVPLLNKHYLKQLMFINLFFSILIIIED
                     SFVIFNVDQYSSLVTKIYNRSVSEDIFSIVICVLLLHFFIKKYQPQKEKTQKQDTSLL
                     IQDFCQDHQFTQRETEIFILLLSHRTNQEIADQLFLSLGTVKTHVHN"
     gene            1123..2142
                     /gene="ptcA"
                     /locus_tag="NOB46_002655"
     CDS             1123..2142
                     /gene="ptcA"
                     /locus_tag="NOB46_002655"
                     /EC_number="2.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine carbamoyltransferase"
                     /protein_id="HCI1059555.1"
                     /translation="MGKKDFITTENYTKEEIQQIVDLSLKIKAAIKNGFYPPLLKNKV
                     LGMIFQQSSTRTRVSFETAMTQLGGHAEYLAPGQIQLGGHETIEDTSRVLSRLVDILM
                     ARVERHHSVYDLATNATIPVINGMSDFNHPTQEIGDLCTMIEHLPAGKKIEDCKVSFI
                     GDATQVCFSLGLIATKMGMEFVQFGPEGFQLNEDHRARLDAICKDSGGSYTISDQIDV
                     IEGSDFVYTDVWYGLYEAELSEEERMRIFYPKYQVNTDLIKRAGKQAKFMHCLPATRG
                     EEVTDEVMDGPNSICFDEAENRLTSIRGLLVYLMRDYAEKNPIDETKKAAAKKDLEAL
                     LGETF"
     gene            2379..3416
                     /locus_tag="NOB46_002656"
                     /pseudo
     CDS             2379..3416
                     /locus_tag="NOB46_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355588.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            3646..4050
                     /locus_tag="NOB46_002657"
     CDS             3646..4050
                     /locus_tag="NOB46_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI1059556.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAKEAHAFCPYSKATRGNIDVEVTIVE"
     gene            4183..5226
                     /locus_tag="NOB46_002658"
     CDS             4183..5226
                     /locus_tag="NOB46_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059557.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEQAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTTTGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            5241..5804
                     /locus_tag="NOB46_002659"
     CDS             5241..5804
                     /locus_tag="NOB46_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCI1059558.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
BASE COUNT         1916 a         1030 c         1255 g         1798 t
ORIGIN      
        1 atattgtgga catgagtttt aaccgttcct aatgaaagaa agagctggtc agcaatttcc
       61 tgattggttc gatgtgacag tagcaatata aaaatttccg tttctcgttg agtaaactgg
      121 tgatcctgac aaaagtcttg aatcaagaga gaggtgtctt gcttttgtgt tttttctttc
      181 tgaggttgat attttttgat aaagaagtgc agtaataaaa cacatataac aatcgaaaaa
      241 atatcctctg agacactacg attataaatt tttgtcacta aggagctata ttgatcgaca
      301 ttgaaaatca cgaaactatc ttcaataatg atcaaaatac taaagaagag attgatgaac
      361 atcaattgct ttaaatagtg tttgttcagc aaaggtacat ccttttttgt tcctcgccaa
      421 caataaattc ctaggtaaaa caggaagagt tgattgccca gataatagag ccagacttta
      481 aaggctgaat tatccatcag tgggatggta atcatccaaa cagccaaagc aagcagtaaa
      541 gcataatgga gaggggaaag tttttctttt tgtagttcgg caagaataga aatggaaaaa
      601 aaggcgtttc ccataaaaat aatcgtttta actgctggcg cactcataaa tacttgatca
      661 taactttgtg caaaggaatt gaggaactcc gtcatataaa taatcgtgtt atcaaaaatg
      721 aagaatgcca aatacaaact gatccagaga aataagttgt ttttttcttt taaataagca
      781 taaatagcaa aagtcatcgt gattgaatat agaatgatca atagaatgtt gtaaacaaaa
      841 atagctatcg tattgaatcc cctttcattt ttttccttac ctcaaatttc ttattttaat
      901 tataacaccg atttttttat ctttactttt aattcctata aacttccttc taaacttttg
      961 taaacccttg gaaaataaat ggtttatatc caaaaataaa ccagcctgta gcacgtatag
     1021 atcggcaatg ataacgttta caactaataa cttatcgtaa actctcactt tttttcctaa
     1081 agtgaagatg caaagcaaac aaattactta ggaggttcca ttatgggaaa aaaagatttt
     1141 attacaactg aaaattacac gaaggaagag attcaacaaa ttgttgacct gtcattgaaa
     1201 atcaaagcgg ccatcaagaa tggtttttat cctcctttgc taaagaacaa agtgttaggg
     1261 atgattttcc aacagtcttc taccagaacg cgggtttcgt ttgaaacagc aatgacacaa
     1321 ttagggggac acgcagaata tctagcacca gggcaaattc aattgggtgg tcatgaaacg
     1381 atagaagaca cgagccgagt tctttctcgt ttagttgata ttttgatggc tcgtgtggaa
     1441 cgtcatcata gtgtgtatga cttagcaacg aatgccacga tcccagttat taacggtatg
     1501 tctgacttca accacccaac gcaagaaatt ggcgatcttt gcaccatgat cgaacatctt
     1561 ccagcaggca aaaaaattga agactgcaag gtttccttta ttggagatgc cacacaagtc
     1621 tgtttctctt taggattgat tgcaacaaaa atgggaatgg aattcgttca atttggacca
     1681 gaagggttcc agttaaacga agaccatcgc gcacgactag acgcaatttg caaagattct
     1741 ggtggctcct atacgatatc cgatcaaatc gatgttatcg aaggttcgga ttttgtttat
     1801 acagatgttt ggtatggact gtatgaagct gaactatcag aagaggaacg catgcgtatt
     1861 ttttatccta aataccaagt gaatacggac ttgataaaac gtgctgggaa acaagcgaaa
     1921 tttatgcact gcttgcctgc cactcgtggg gaagaagtca cagatgaagt catggatgga
     1981 ccgaactcga tctgttttga tgaagcagaa aatcggttga cttcgattcg cggtctctta
     2041 gtgtacttga tgcgagatta tgcggaaaaa aatccaatcg atgagaccaa aaaagcagcg
     2101 gctaaaaaag acttggaagc tttgctaggt gaaacatttt agacgcaaga gatgaggaaa
     2161 ggaaataatc tgcgtatcat gacgatgcgt gaggattgtc tctgttctag aggaggggct
     2221 aacgatctga aaatcgattc tttctagcag aatcttgatc tcacactaat gtagctttta
     2281 tgccgcacta gaaatcatac gaggtgagtc cgcaggttac aagaatcgtt caatcgctgg
     2341 tccaacctta ttcccttgta ccggaaagga agaaaacaat gggagaaaag aaaaaattta
     2401 gtttgatgag tgctatatta tctgttattt gtgttgtatt tgtggcagaa gcggctgcac
     2461 cggtagcagc aatcggaaat tcacaatttt tttggtggat ctttttattg attgcattcc
     2521 ttttgcccta tggattgatc tcgtcagagt taggaacaac ttatatcggt gatggcggta
     2581 tctatgattg ggtgacacaa gccttcggac atcgctgggg atctcgcgtt tcttggtatt
     2641 actggattaa ttatccactg tggttagctt ctctagcagt agtctgccct gatttattga
     2701 tgacgatcac aggcagcgaa ttttcaacag ctgctgctat catgatcgaa ctgatcttta
     2761 tatggatcat tgtttggatc agtttttatc cggtcagtga cagtgtgtgg attttgaatg
     2821 gagcagctgt tatcaaaatg ctgctggcaa tcttgattgg tggcttaggt ctctatactg
     2881 cgtttactaa gggtgtggcg aatgagttta ctctttcttc catgctgcca agtttcaatt
     2941 taaatagttt gtcctttatt tcagtaatca tttttaactt attaggattc gaagtgattt
     3001 gtacattcgc gaatgatatg gaaaatccta aaaagcaaat ccctcaatcg atcattgccg
     3061 gtggactggt gattgcagct atttacattt tttctgcatt cgggatcggt gtagcaattc
     3121 ctacggatca gattagtaca ggcagtggat tgatggatag ttttaagtta ttgacaggat
     3181 caacaggcgg ctggttcatt atttcgatgg cctttttatt cttactgaca ttgtttggca
     3241 atatgatttc ttggtcgtta ggggttaaca atactgcttg ttatgcagcc gaaaatgacg
     3301 atatgccgaa agtatttgcc aaacgcagca aaaaaaacgg catgcctact ggtgcggcga
     3361 ttatgaatgg tattgttgct tctatcattg gtgcgatcat cgttgttgct gtagtatcat
     3421 ttttcttggg acgttcaaga ggttaatcgt caaatatatc agcaatttta cctattatct
     3481 taaggagcag cttttcgctg cttctttttt tgtatagata aactgcttct atcactgatc
     3541 atcgatgttg tctaactgat gtcgccgaat gcaagcatta cctttgccag attaaaaaat
     3601 actcgttaca cttaatatag aacgacgaaa gaaaggatga tctcaatgaa aaaaatgtac
     3661 gaaacagcaa tgatcaatcg tggaggccgt gatggcgagg ttgaggcacc aaacggaagt
     3721 atgcacatga agatcgaccg cccaggaatc catagtgaag ggacaaatcc ggaacaactt
     3781 tttgcggctg gatacgcatc ttgcttcaac ggcgcggttc aacacatgct ggaagaaaat
     3841 aatcttgagt ctgattctga agtcaaagca cgggtatctt tatttcaatt agaagatggg
     3901 ggctaccaaa tcggggttgt tttagaagtt tctttgccag gacttgagaa ggaccaagca
     3961 gagaaaatcg caaaagaagc ccacgcattt tgcccatact ctaaagcaac aagaggcaat
     4021 attgatgtgg aagtgactat agtagaataa gggattctta atgttactat aaatgagatt
     4081 atgaaagatc ctataaagaa acgctagtaa aagaaacatg tagttacggt aattaatagc
     4141 ggtatatgta cgattgatcg aatagaacaa ggaggcaaaa aaatgacaca gcgggtagca
     4201 ataatgattt tagtgttgct ggtcattggc ctccttgttt actatgtcct aaagtttaag
     4261 cattggaagc agcaacggat acatcaggat attgaaaaaa agttaaaacg gtatcctatt
     4321 gttcaagcag cttgggaaca ggctgaagca aaacaatata acattcctgg attaacagaa
     4381 acaagaatgg tggtgccgga aaccggcgaa aatgaggttt gtcaatggat gacgccgcaa
     4441 gggttggctt tttctcaaga ttttgtgttt atttctgcct actgctatga ccatcagcat
     4501 cattctatta ttcatgtact ggatagagaa acaggacagc cgatcaaact gctgatttta
     4561 cctaaacggc cacatgtagg gggcttagta tatgatacaa aacgggaact tttatggttg
     4621 acaaccacag gatctgctac tggacgagta gccgctttac gtttgatcga tatcttagca
     4681 gatacatctg aagagacggg acagccaatc gcttattggc tgacaactga tctctcagag
     4741 attccacaag catcgtattt gactcaaaac aatgatcaac tggtatctgg caacttcaca
     4801 ctaaaaggtg aaggacagtt gactttctat ctattgccga cgatagctga aatgaaaaca
     4861 gcaattcgcc gcaaagacaa aatccaacca accgtgacaa tgagcagaaa aacatctgat
     4921 aagattcaag gtgtggcttt ttatggccat tatctcttag ccagtcgttc ttatggtcct
     4981 tatacctcgg aactcttagt gtccgagcgg gactctccta gccggatcct aaaacgaatc
     5041 aaatttccac cgtatttgga acaaatcgtt gttgtagaag atcgtctagc agtattgttt
     5101 gaaagtggcg ccgcagcgta tcgcgagaaa gccaatcctg tgttagccaa tgttttatta
     5161 ctagacttag caacgttgct tcatgcaaat aagcgtccca aaaagattgc tgcaactaaa
     5221 aaatagtcgg acaactcaag atgatcactg ttgttcataa agaacgacaa gaaaaatcat
     5281 ctagcgatgt tcgactatgg gtttatttag gaagtatttc tactaagatt caatatggct
     5341 atacagattc ggcgaaaaaa caaggcaatg ttaagttttt gagaatcaca gatatacaag
     5401 agggacgtgt aaattggtcc agtgtgcctt actgtgatat tagtaattct aaactagttg
     5461 atttaagatt ggaagaaaat gacattttga tagcaaggac aggaggaact atgggaaaaa
     5521 gtttcttggt taaggaaata agtgaggaat ctgtttttgc ttcttacttg attcgaatta
     5581 ggttagttga gaaattatta tcagaatacg tagactgctt cttagactcg ccattatatt
     5641 ggaagttatt agaaaaaatt tcttacggaa ctgggcaacc aaatgtaaat ggtacaaatt
     5701 tatctaaact acttatacca ttaccacctt tagaagaaca acaacgcatg actactaaaa
     5761 tagaaatgat aagaagatct attcgtagaa tcaattttga gtaaatataa cggacctagc
     5821 atccatttta taccagatga tgctaggtct attatttata ttttatggaa tttaattgat
     5881 ttgttctagt gttttaatat tattacgaca gtaaaaaaat agtttgattc ttctaacatg
     5941 aatgaccatc tagaagtgga aatgtataaa agatttattt tatgaagttt tcctaatat
//
LOCUS       DAIGUC010000098         5983 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.102, whole genome shotgun sequence.
ACCESSION   DAIGUC010000098 DAIGUC010000000
VERSION     DAIGUC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.102"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(48..917)
                     /locus_tag="NOB46_002660"
     CDS             complement(48..917)
                     /locus_tag="NOB46_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HCI1059559.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(1209..2819)
                     /locus_tag="NOB46_002661"
     CDS             complement(1209..2819)
                     /locus_tag="NOB46_002661"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HCI1059560.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4012..5352)
                     /gene="glnA"
                     /locus_tag="NOB46_002662"
     CDS             complement(4012..5352)
                     /gene="glnA"
                     /locus_tag="NOB46_002662"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HCI1059561.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(5380..5772)
                     /locus_tag="NOB46_002663"
     CDS             complement(5380..5772)
                     /locus_tag="NOB46_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI1059562.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         1755 a         1278 c          982 g         1968 t
ORIGIN      
        1 caaaagtcgt tctccattcc tatatatcgt atctgttatg tggatgctta cgctttgtta
       61 gctgaaccga accagtcgat atgagattta gcatcttcaa cgattgctgc tttacctgga
      121 gctaataatt tacgagggtc gaatccttta ccttctttat ctttaccagc ttcgatatat
      181 ttacgagtag ctgcagcaaa tgataattgg aattcagtgt taacatttac ttttgagata
      241 cccattgaga tagctttttc gatttgatct tgaggaatac ctgatccgcc atgtaatact
      301 aaaggcatgt ctggacctac agcatcagca attgcttgta agtggtcaaa agctaatcct
      361 ttccagtttt ctggatattg accatggatg ttaccgatac cgcaagctaa gtagtcgata
      421 cctgtagcaa ccatttgttt gcattcttca atatcagcta attcgccgtt accgatgatt
      481 ccgtcttctt ctccgccgat tgaaccaact tcacattcaa ctgagatacc ttttgcatgt
      541 gctttttcaa caacgtcttt agctaatttc aagttttctt caaatggtag atgtgaacca
      601 tcgaacatta ctgaagtata gcctaattcg atacattcca aagcagcttc gtaatcacca
      661 tggtctaagt ggatagcaac tggaacagtg atgttcattg cttcaactaa atcagtgatt
      721 aaatctttac agattttgta accacccatg tatttagctg cacccattga tgtttggata
      781 agtactggtg cttgttttgc ttcagccgct tcaaggattg cttgagtcca ttccaagttg
      841 tttgtgttga atccgccgac agcgtaaccg cctttacgag cagcttttaa aaattcagct
      901 cctgatacta ctggcataat aaaattcctc ctaagttttg taaaactaaa tttgttaaga
      961 caattcttaa ccaacgaccc tattttacca aacatttcgg tagttttcta ctaaaatcaa
     1021 tgaaaatgaa aattttcaag aagttttttg caaaaaataa aatatccaat agcgctttaa
     1081 tcgaaaaaag tcttttgctt tctatctttt ttcctacaaa taataacaaa tcagaaaaag
     1141 agaaaagtga caagaaaatt gcttatcccc ttctcttgct acttttctct ttctatcaag
     1201 ttcaaaaatt attttgtttc gtgatctgct aatgatgctc cgacaaatgc tttgattaat
     1261 ttttgcgggc gatttggacg agaaatcaat tctgggtgga attggcatcc cacaaagaat
     1321 tttttctctg gcagctctac gatttctact aaacggttat ctggtgagac acctgaaaag
     1381 actagccctt gttcttcaaa caattgacga tatttgttat tgaactcata gcggtgacgg
     1441 tgacgttctt gcacaacatc ggctccatca tatgcttcag ccgtcttcgt tccttttttg
     1501 attttacatg ggtataatcc aaggcgtaaa gttccaccca aattctcgat gttttcctga
     1561 tcagccatta aatcaataat attgtttgct gtatctggat tcgtttcagc tgatgacgca
     1621 tcttctaatc caacgacgtt acgtgcaaat tcgacacaag ccatctgcat accaagacaa
     1681 atacctaaaa acggaacgtc attttcgcga gcataacgaa tcgcttcgat tttcccttct
     1741 actccgcgat caccaaatcc accaggaacc aagattccat ctgcgtcttt caaacgttct
     1801 tctacatttt ctctcgttaa ttcttgtgct ttgatccaat cgatctcgat gtctgaatta
     1861 taggcgaaac cagaatgttt caatgcttca actactgaga tatatgcatc tggtaactcg
     1921 acatatttac cgacaagcgc aatccgtact tttttcttca agttcaagac acgttcttct
     1981 aattctttcc attctgtcat gtctgcttct ggtgtatcta gttttaaatg gtcgcaaaca
     2041 atttgatcca ttccttgtgc ttgtaaaact aatgggatgg agtaaagtgt atctacatct
     2101 ggcgactcga taactgcttc tggttcgaca tcacaaaatt gtgccaattt gtttttcacg
     2161 ctttgagaaa caggttgctc tgtacgtacc accaaaatat tcggttggat acctaaacca
     2221 cgtagctctt ttacactgtg ctgcgttggt ttagttttca tttctccagc agctttcaag
     2281 taaggaatca atgttgtatg gatatacata acattatctg taccgacatc tgctttcatt
     2341 tgacgaagtg cttcaaggaa tggcaaagat tctatatccc ctactgttcc ccctacttct
     2401 gtaatgatca catctgaatc agtcatttta gctgctcgca tgattttttc tttgatctca
     2461 tttgtaatat gaggaataac ttgaacagtt gctcccaagt attcgccctt acgttcttta
     2521 cgcaaaactt cagaatagat ttttcctgtc gtcacgttgg agtatttgtt caaattgatg
     2581 tcaataaaac gttcgtagtg gcccagatcc aaatctgttt cagcaccatc atctgttacg
     2641 aatacttctc cgtgctgata tgggctcatc gtccccggat ccacgttgat gtatggatca
     2701 aatttttgga tagttacttt taagccgcgg tttttcaata agcgtcctaa agaagctgca
     2761 acaatccctt ttccgattga tgaaacgaca ccgccggtca caaaaatata ttttgtcata
     2821 agttcaaaaa ctccttttta atttatgtgc aggaaaagtc tcagacaata aacaaagctc
     2881 cctattcttc aataagaata gggagccgaa atttctgtaa acttctgacc ctctaaaagg
     2941 gtgcccaagg tgtataatac aagctgacta agggaaagtc aagtactcaa atgaatacta
     3001 tccgcttaca attttttctt tttcgatatc ctttgagaaa ttatttctta agtcctttat
     3061 gagtgcaaaa aaaatttaac ccacataata agcttgatat aaacatagct aacgttaaac
     3121 ctaagcaaat cagaaaatcg ttactgaaaa attttaagtg aaataataga taaaaaaata
     3181 aaacaaacat tatgatagat aatatcccac ctaacaaaga actacttttt cctacttgca
     3241 gcaacagttt atatagctta tcgtagaaac aatctttttc tttcaccctt atttacctcc
     3301 tttacgtaaa aaacgtagtc cacagttctc ggatttttgg catatctttt ctattaaata
     3361 atatcaaaaa caaaacaatt ccactaattt tttcaaagat gacctttttt tcaacaaaag
     3421 tgccttgtag ggattcattg aaggtaacga atcacataag taaaaaataa ggagatgcga
     3481 caaaagtcgt gcctccttat ttctaaataa acggtgttct cctgccaact cctcggtcac
     3541 aagtcacaat atccatcaaa catgagaagc tgtttttgaa attatttctt gtgattcgga
     3601 gttaaatggt aggctcacaa cctctggata aacggtattc aaaagccagt ttctcggtat
     3661 taagccaaat ttatgcaaaa atgtagaaag ccattttcac aaaatttttc ttaatactcg
     3721 aaactaaacg tctttttcaa aacctcttgg taaacggtgt tcaaaagctt gcatctgcgg
     3781 taataagttc agccaattca aaaacaagaa aagctgtttt tgcttggcta ttcttattac
     3841 ttgttgcagg gcagcttttt cacaacctct ccactaaacg gtgttcaatc agctgaccct
     3901 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt tttccgttag tttctctaat
     3961 actcaggtca aaacgctgat ttcacagcct ctaattcacg gtattcctgt tttaataaag
     4021 ttctagatat tgttctcttt cccactcgga aacagtttgt ctgaatgccg cccattcgag
     4081 acgttttgct tcaacaaaat ttgagaagat atgttgtcct aatgcgtcaa tcattacatt
     4141 atccttacgc aattctttga tagcattatg gatagttgaa ggtaagtcct ggatatgtgc
     4201 agcttctctt tcttcctcat ccattacata aatgttacgg tcaacagctg ctggcggtgt
     4261 gatctgatta cggataccgt ctagtcctgc ttgcaacaat actgccattg ccaagtatgg
     4321 gtttgcagat ggatcaactg accgcaattc caaacgtgtg gataaaccgc gagattctgg
     4381 tacacgtact aatggcgaac gattacggcc actccatgcg acataaacag gcgcttcata
     4441 acctggaacg agacgtttat aagaattgac tgttggattg caaacggctg tgtaggcacg
     4501 agcatgtttc agcaaaccac ctaagaaatg ataagctgtt tcacttagtt ccaattcacc
     4561 gtctttatca tagaaaacat ttccttcatc attgaacaaa gacatattgc aatgcatacc
     4621 agaaccattg atcccaaata acggtttcgg catgaaagtc gcgtgaagtc catgcttgcg
     4681 tgcaatcgtt ttgacaacga gcttgaaggt ttggatatta tcacaagcat ctaccacatc
     4741 tgcatattta aagtcaattt catgctgtcc tggcgctact tcatgatgtg aagcttccac
     4801 ttcaaagcct agactttcta attccaacac gatgtcacgg cggcaatttt cacctaaatc
     4861 tgttggtgca aaatcaaaat aaccaccttt atcattcaag gtcgttgtga tcccaccgtc
     4921 ttcgtctaat ttaaataaga agaattctgg ttcaggtcct aaattgaaag aggtaaaacc
     4981 aaggtcgcgc atatctttca atgctcgttt caaattcccg cgaggatcgc cggcaaatgg
     5041 tgtcccatcc ggattataga tatcacaaat taaacgagca acttttccat gagcactttc
     5101 ccacgggaag atcatccaag tggagagatc tggatacaaa tacatatcgc tttcttcaat
     5161 tcgaacaaat ccttcaatcg aagaaccgtc aaacatcatt ttattttcta atactttgtc
     5221 gatctggctc actggaactt ctacattttt gatcgtacct aagatgtctg tgaacatcaa
     5281 tcgtaaaaat cgtacgtttt cttcctcaat gattcgtttg atttcttcac ctgttatctg
     5341 tttctttacc atggtatccc tcttcctttt ttaatttatt cagtcaaaga attgtctttg
     5401 caatccttgc gactgataat gacctgtttt gcttaaccca ccttgcgcca aaatctcatc
     5461 acgaaaaatt tgtcgaacgt catgatctgt caacggcttc ttgttttttg cttcttgttt
     5521 tttcgcctgt gccatttcgt atacacgttt gatcccagcc atattcaatc cctctgaaag
     5581 atagtcttta atctcaagca acatatcaat atcattcagc gaatacatac gtcggtttcc
     5641 ttcgcttcgt tccggatgaa ctaaatcttg ttcttcataa tagcgaattt gccgagcaga
     5701 caaatcagtc agcttcataa ctgtaccaat tggaaatacg gacatagatc ggcgcaattc
     5761 cttttctccc atcagacgtc ccctttcgtt ttataagttg gctaaagtgt accaattaaa
     5821 aaaaatattg tcaactgcat atgttaggtt ttctaacatg agatctctat tttttataaa
     5881 ataacaaaaa aataagaaca caaaaaaggt atctagttga ttttcgtacc agataccttt
     5941 tattttttat tatactgtac tatcctttat tagtgttttt att
//
LOCUS       DAIGUC010000099         5856 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.103, whole genome shotgun sequence.
ACCESSION   DAIGUC010000099 DAIGUC010000000
VERSION     DAIGUC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.103"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="NOB46_002664"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="NOB46_002664"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCI1059563.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="NOB46_002665"
     CDS             complement(1172..1867)
                     /locus_tag="NOB46_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCI1059564.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="NOB46_002666"
     CDS             complement(1880..2596)
                     /locus_tag="NOB46_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HCI1059565.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="NOB46_002667"
     CDS             2926..3531
                     /locus_tag="NOB46_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HCI1059566.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLCEHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="NOB46_002668"
     CDS             3856..4179
                     /locus_tag="NOB46_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCI1059567.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="NOB46_002669"
     CDS             4361..5731
                     /locus_tag="NOB46_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCI1059568.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
BASE COUNT         1665 a         1154 c         1096 g         1941 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gtgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttt
//
LOCUS       DAIGUC010000100         5781 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.104, whole genome shotgun sequence.
ACCESSION   DAIGUC010000100 DAIGUC010000000
VERSION     DAIGUC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.104"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(96..698)
                     /locus_tag="NOB46_002670"
     CDS             complement(96..698)
                     /locus_tag="NOB46_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059569.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            821..1021
                     /locus_tag="NOB46_002671"
     CDS             821..1021
                     /locus_tag="NOB46_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059570.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            1033..1359
                     /locus_tag="NOB46_002672"
     CDS             1033..1359
                     /locus_tag="NOB46_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059571.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            1512..2564
                     /locus_tag="NOB46_002673"
     CDS             1512..2564
                     /locus_tag="NOB46_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI1059572.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            2640..2858
                     /locus_tag="NOB46_002674"
     CDS             2640..2858
                     /locus_tag="NOB46_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059573.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            2845..5523
                     /locus_tag="NOB46_002675"
     CDS             2845..5523
                     /locus_tag="NOB46_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059574.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            5514..5711
                     /locus_tag="NOB46_002676"
     CDS             5514..5711
                     /locus_tag="NOB46_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059575.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
BASE COUNT         2224 a          758 c         1075 g         1724 t
ORIGIN      
        1 tatcgtgcac cgctttttgt tgtgtacttt tgtattgaca taactaatct ctccaatctg
       61 ataacttggc gagttggctg attgaataat tagttttatt gaagttttga tattaatcga
      121 gctgttatct ctctttttag attgttaacc tgtacttggg ttaagttgcc aaataactca
      181 gattctaact cttttctttc atcgatattt aagtttaaag ctttattaat aaacttcttt
      241 tgtttggcaa atagaatcgt gtattcaaag gagtcctcta gaatactttt taaaaaaaga
      301 aagtcggagt catcttcttg aagtttgact tcaagtaaag aagtcatgga aaagtataga
      361 ttagataatt cagtaaaata atctgagtca agactggcaa tattcttgac tattttgtcc
      421 tttttttcta aacgagcagt ttttattcta tcaagattag gttgttctat ggaatttgtt
      481 tcgtctaatc ccatcaaata acttacagga acatggaaat aatcagcaag gatattccat
      541 gtttcagtat ttctaggatt tcgctcacca cggtaatagt tcgtaagagt tgtatagtta
      601 ataccagttt ctgtactaat ttgtttaatg gtctttttac tggaatcaat ataaaatttt
      661 attctattca aagtaacgcc ccctatagta aattccaaac tattatagca tgaaaaccac
      721 aaattgagta atattttaat tgatattact cgttttgtgg tttaaaatgt gcttattaag
      781 ataaaaacca caaagtgaat aatttgaaag gaggcgctga atgataactc ttaatgatca
      841 attcattaga agcttaagaa gacatagagc cgatcttata cttactaaaa acgatgcagc
      901 aaaattgata ggtataaatc ggaaaacata tgtcaaaatc gaaaatggga gcaaagaaag
      961 tattagagca tctacttatc aaaagttggt aaattggtta cttaatgatt tgaaaatcta
     1021 aataaataca acttggcgag ttggctgatt gaagaaatag aaaatgagag gagaaaaata
     1081 atggatgcag gaattacagt aatgttagat aaacaacaaa cgaatcaatt gaaaaattat
     1141 gtttttgaaa tgacaaaaga ggctattgat caagcaagaa ttgataccgg attagaaaga
     1201 ccatttctaa aaggaaaaga gatggctaaa tatttgaatg tatcatatac aacttttttg
     1261 aaatttaaaa gaatgggatt gccagttatt ttattagaaa aaatggagtt gttttcaaaa
     1321 gaagaatgca aaaaatggat attgagtcat caaatttaaa aaacacctcg ttttttaaat
     1381 ttgatgaagt agaaaaaatt aaaaagagtg ttcccgtcag tttgcagatc gggggaacac
     1441 tcaataataa agttctgaga aaactttatt tgaatctatt atagcaaata aaatcagaag
     1501 caggtgtgac aatgaatgaa aaagaagttg aaagcttagt tgaaaagcaa ggctattcta
     1561 attctgatat atatgcagaa ttatactatc aatatcctat ttttttaaac gtaaatgaaa
     1621 aatataagaa aatgaaacta agttctaagt tagtttatat gttactaaaa gatagaaata
     1681 gactttcatt gaaaaataac ttgtatgatg agaatcaaaa aatttttttg atatttgaaa
     1741 tcaaaaatct cgtagaaatt tcgggaatgt caaaaaatac aatcttatca gcactagatg
     1801 aacttcaaaa agttaaactt cttgtgaaaa gaaaaaatgg cttcaataaa agtaaaatgc
     1861 aaatgttccc aaatttttat tatttgttaa agcctgttct gtgcaaagat gatgtttata
     1921 aaattaataa gataacccat caagaaaata gacaaaaaaa cttgatagtt caaaatttga
     1981 actatggaac aaatcaatat tctgttgata attcaaaatt tgaactatgc gacacatcaa
     2041 tgaaaacaag agacaaaaac aattttgctg atagttcaaa aaatgaacta gaattatata
     2101 agtcttataa agatagtaaa gatattaaag aatcacataa tgatgatctt cttgaatcac
     2161 tttcaactaa aaataataaa ttagatgaag aattgatcga aacatttatt gaagaaaatc
     2221 ttcttaaaca aatatgggga gaaagtattg tgaattgctt aaaactggct agcaatagtg
     2281 attatcgtca attcgacaac tggtacaaaa aattcaaata tgcgattaga tctgctgaaa
     2341 aagaacaaaa aattcaactg aaaattatct atgaaatttg taataacaag tattttgtag
     2401 atcatgttag agaacagcta tcaatgactt tacgtgactt gatacgaaga gcaaaaacag
     2461 atcatcgtat caaacaaaaa gacgattata tctttgcttc tctaaaaaat aaagcgttag
     2521 aactaattga attgcaaatc agcgaaggaa tagataagca ataagaatag aattgagtca
     2581 aatgaaatgg aggggtatct ccacttcatt tgagaacttt gaatatagga ggggttattt
     2641 tgattaaaaa tcgtttaata gatcaagttt ggtgtctaga tcaaaataca gatagtctcg
     2701 aattaatcga gactatttgc ttcaacacta tagttctcga tttaagagct gaaaatgata
     2761 attgtgtaac tcatgtcata attaatcaaa aaatggctca gaagctctct gagagcctca
     2821 gaaaatgggc taagggaggt aacgatgaaa ataattgaaa aaaagattgc caataaaaaa
     2881 ataaattggt tggttgttaa ttttcttgtt ctgatagcta tgattatttt tacaagtaat
     2941 attgctcatg cgagtatttt caattggttt gatgacacaa aaagtcaaac agagtttttg
     3001 aataattctc tttatagacc ttacctaaaa aagtacaatg gagatttcct tagtcagttc
     3061 gggatttggc tcggatgggc tgtggtaaaa ggcatgttta ctgtgacaga ttcgattcaa
     3121 aatatgattc cagatgtgct ggatttgttc aatttcattg aaagtacagg gctaaataat
     3181 gtttatcaat cagccgtaaa tacaattgtc attggattaa tgatcctttc attgatgttt
     3241 gttggttaca aaatgattac tggaaaagga acagtggatt taaaatcggt tggaatgaac
     3301 gtagtgatgt ctatagcatt aatactttta atgccaacca tgatttctag tggtattcaa
     3361 tttgctaaaa cattttataa ggactctact acgattacaa attcagatga cggagtcgct
     3421 tggtcattga taaaacaagg agtaacagat ttagcatata ttaataaaac agatcagtac
     3481 tcaagcattg ataaaacgga ggatcgaaat aatttaacac gaaaaaattt tcaacagacg
     3541 gatctcacac aagtgttaac ggataaagtg attgataaat tggaaaaaga aaatccaatt
     3601 gcggacaatc ttcgttatga attagttgaa aattctaata atgaatttgt tgctacaaag
     3661 ttttctgaca acttcttatc aacattttct gatagcttga aatcaggcta ttaccgatac
     3721 caagcaaatc tatgggggat ttcaattggg ttgacagcgt tagcaatcgc ctatgtgttc
     3781 agcgcgtttg tgatcattac agcaatacta gaacttgcat ttaaacgtgt gttaggtgtt
     3841 cttgtttttg caacagatat tgagacagga cagcgttcaa aagttgttct atcagatatt
     3901 ctacaatgtt acttaactgt tgggtttcaa ggatttgggt tatcaatgtt tgctatgttt
     3961 atcaattttc tgaactcagg acaaggtatc tcaacaaata tttttataaa aacaattgct
     4021 tatatctgtg ccgtttttgt tttaatcaaa ggcagtggaa cagtcatgag atactttggt
     4081 gttgatattg gactcaaaga aggctatggg caacttgctt ctgcttttgg aatgggcgca
     4141 atgctgttta gaaaaggatc aaatggattt aatcgtgcta aaggaagcgg agaaggagaa
     4201 gatcgaaaac cagaaaagaa tttcggcgaa actctatcaa aaaaagctgg caaaactgga
     4261 agagctttgg gatatgccca tgaacgtgga ttatccggtt tagcttcaga tggagctaca
     4321 atggctagtg aaagagcaac aaaaccattt aagagtatgc gtgatatagc taatgatacc
     4381 aagaataagt ttaaagaagg tttagatgat ggtacagtgt ccgctattaa taaaaatagc
     4441 aaacctatgt tagctaaaaa taaagaagat gaaactggaa aatatgctga ttccgtgcca
     4501 acacgtcttt cagatagaaa agatggtgct aaagttgaaa atgccgatag aattatgtct
     4561 agttctgaac gtatgcgtga agcaatgaaa aataatgctg aatcgaataa taatcctgca
     4621 agcgcaattc agcaaaaagt ccaacaagat attgaagaac gtaaaaatgc tatgcacggt
     4681 caagctaagt ctgctgaaga attaattaat cagaagcgtc atgaagcgaa atacacgcct
     4741 gaagcaatga atcgcgagga aataatgtta aggaaacgtg tagaagggcg gacaggcgct
     4801 aatattgacg gaaaagaagc gttgaccaaa gaaagaattc aagaagctaa aaattcaaat
     4861 acaggattag aaaaattagt caaagaaaat ccacaaaatt ctacaagtag tcatggtggc
     4921 cgatcagtag atgtccgaga aaatattcaa ggttcactga atggtcatgt tggacggaat
     4981 gttgatgtaa gagagaattt acaaagttct tcaaatgctc aaggtactaa gacaattgat
     5041 gttcgagaaa atctgcaaag tagcagtaca agtcaaccaa aaacagtaga tgttcgagaa
     5101 aatgtacaaa attctacaag tagtcaaggg tttaaatcag tggatgtccg agagaatgtg
     5161 caaggtagca gtgcaagtca accaaaaaca gtagatgtcc gagaaaatgt acaaagttct
     5221 acaagtagtc aaggattcaa aacagtagat gttcgggaga acattcaaaa agatagtgga
     5281 gaaatgaaag aaaaaacaca aaaaatcaat atcgttgaag acagaaagtc agcgaaaaaa
     5341 tttgattcaa atcatgaaac agtgattatt gatagtgaaa tccgtgaaaa tgataaggga
     5401 tcaaaatcaa gacgaagatt cacttatgaa gacaatgagt tattcagaga tacacttaat
     5461 gatcctaatc cacttttcga taatttatta agaaataaaa gggggggatt gtcatgcaat
     5521 taattctaaa gattagtacg catgatttct tagaacttga cgaattatgt gaatcagtaa
     5581 agaacgcaac aaatgaaaaa atcacggtca ctaattatat tgaactgatg attcaagaag
     5641 aattaaagat gaaaaatgaa atagagagca atttcaaatg ttgctctcta gaaaaaaatg
     5701 tgaggggata atcaatggat gataaacaaa aaatgtacga aaaaaatcgc aaacatagtg
     5761 aggccttaaa ttttcgtgtc g
//
LOCUS       DAIGUC010000101         5769 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.105, whole genome shotgun sequence.
ACCESSION   DAIGUC010000101 DAIGUC010000000
VERSION     DAIGUC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.105"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..500)
                     /locus_tag="NOB46_002677"
     CDS             complement(<1..500)
                     /locus_tag="NOB46_002677"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059576.1"
                     /translation="MVEILKEITTYEIIEKTTGLTCYTYQQANEKYRLHFFCYVFDNQ
                     DELLANYEEINDQIAYSFQSQLKRKIERWNIYFFLFVKAKVAKPIKASIEQDKYATRK
                     VIVDNFREFATNDAQKEAQKEAQKEAQKNKIQKRLLLNLEQTKPVKKLAKDERQNDEK
                     IIHLLA"
     gene            complement(516..1355)
                     /locus_tag="NOB46_002678"
     CDS             complement(516..1355)
                     /locus_tag="NOB46_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059577.1"
                     /translation="MYVEREGKCYLTGIITKLQSAGQQGIVEGIHIAHIVAFFLEEFD
                     IMLVPRCLNDFSEYLASIINELREVGGQENKLIFLIEKCYRECFSDITPKLIHNRLSD
                     YLFLPSQKNEDYTNKFLWIAWLEILLYKLLQTNIAFEIDDCFKLLTQEKERAGIHVLF
                     TNHLTLDRFIGSLFRSTLYDKLDKQDVLFVTNQRRKFRGGSIAKREQIEGIVVNIDHP
                     EVSDRLTIDNPNEKKLFPIVHVDYIENEIDQILHDTKGLTAVEFSQRFPEELTRLFEE
                     IAN"
     gene            complement(1808..2902)
                     /locus_tag="NOB46_002679"
     CDS             complement(1808..2902)
                     /locus_tag="NOB46_002679"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059578.1"
                     /translation="MQGQDCNEREMITVKALPAYDGDCLIVQYGEEDQRTNLFVDGGQ
                     GQQVVRQLKEEIATISQKGECIDLLVLTHIDADHIRGFLSLFSQSSFDKSCIKRVFFN
                     SRKLLSQKFDTKVVYDDQLEIVQEKSEISFKQGESFDRYLENLRIEKMTVIDNSCQPK
                     LLNGAKMTILTPDEASLRKLYTDWEKAIQKETRDQLISGRNVNHQGSVEELIKKAFQE
                     DRAVANGSSISFILEYEGKRLLMLADAHPSTVTAKLKELYGEKELHFDLVKVAHHGSK
                     ANTSDDLLKQIECENYLISSNKGNRHGFPHKEALSRIVYHNYTKKRPTNFYFNYSDAS
                     EGLFTNEEIKKYGIQLIKKKMNERVLTIDI"
     gene            complement(3321..3731)
                     /gene="arsC"
                     /locus_tag="NOB46_002680"
     CDS             complement(3321..3731)
                     /gene="arsC"
                     /locus_tag="NOB46_002680"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HCI1059579.1"
                     /translation="MKKIYFLCTGNSCRSQMAEGYARQLLSASDVEIKSAGIETHGLN
                     PRAVQVMAEDGIDISNQTSDLIDQDYFTQADLIITLCGDAKDKCPTIPVGVQHIHWDL
                     TDPAQAVGTEAEITSAFRKTRDRIKAMVIELKNQ"
     gene            4285..4848
                     /locus_tag="NOB46_002681"
     CDS             4285..4848
                     /locus_tag="NOB46_002681"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059580.1"
                     /translation="MFGFIALMFFLPLTKTHADVTVTNDCTDPSHSFTASINADNGKD
                     VSSDYYKVTVGQTESWRRNDPRGHILAIVYLEQLRTYYTPTNAAYSFKDGKLYSQGST
                     TEITPLKVETNSLVTRSMNVNMINLSTSLTTVSLSKWKSGGSTDYFALNHLDSETWSR
                     NDDPRGFLVSVLYNGGFSKEYIYYLPI"
     gene            4920..5769
                     /locus_tag="NOB46_002682"
                     /pseudo
     CDS             4920..5769
                     /locus_tag="NOB46_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341471.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1740 a         1243 c          927 g         1859 t
ORIGIN      
        1 tctgctaaca aatggatgat tttctcatca ttttgccgct catccttagc cagtttcttt
       61 actggttttg tctgttccag attcaataat aatctttttt gaattttatt tttttgtgct
      121 tctttttgtg cttctttttg tgcttctttt tgcgcatcat tagtagcaaa ttctcgaaaa
      181 ttatccacga tcacctttct ggttgcatac ttgtcttgtt caatactggc tttgattggc
      241 ttcgctactt tggctttgac aaaaagaaaa aaataaatat tccatcgttc aatcttcctt
      301 tttaattgac tttgaaaact gtaggcaatc tgatcgttga tttcttcata gttggctaat
      361 aactcatctt gattatcaaa tacataacaa aaaaaatgga gtcgatactt ttcgtttgct
      421 tgttggtacg tgtaacaggt caatcccgtc gttttttcta ttatttcata cgtagtgatt
      481 tcttttaata tctctaccat tgttacctac ctccattagt ttgcaatttc ttcaaacaaa
      541 cgagttaact cctctggaaa cctctgagaa aactcaacgg ctgttaaccc ttttgtgtcg
      601 tgtaaaatct gatcaatttc attttcgata taatcgacat gaacaatagg aaataatttt
      661 ttttcattgg gattatcaat cgttaaccga tcagaaactt ctggatgatc gatgttcacg
      721 acgattccct caatttgttc tcgcttggca atactcccac cccgaaattt tctcctttga
      781 ttagttacaa acaaaacatc ttgtttatcg agcttgtcat aaagtgtact tctaaataaa
      841 ctcccaatga aacggtcaag tgttagatga tttgtaaata atacatggat accagctctt
      901 tccttttcct gagtgagtaa tttgaaacaa tcatcgatct caaaagcaat atttgtttgt
      961 aataacttgt aaagcaagat ctccagccaa gcgatccaca agaatttatt ggtataatcc
     1021 tcatttttct gagaaggaag aaacaggtaa tcacttaacc gattatggat caatttaggc
     1081 gttatgtcgg aaaaacattc acgataacat ttttcaatca gaaaaatcag cttattttct
     1141 tgtccaccta cttctcgtaa ttcatttatg atagatgcca aatattcact aaaatcattc
     1201 aagcaacgag gtaccagcat gatatcaaac tcttctaaaa agaaagcaac gatatgtgcg
     1261 atatgaatcc cttcaacaat tccttgttgc cccgctgact gaagtttcgt aataatccca
     1321 gtcaaataac acttcccttc tctttcgacg tacactcctg atcctgagca acctcgtatg
     1381 ttctcatact ccgtgttgtt agacgatcct atttcattgt ccagtaccaa tttaaaaata
     1441 tctggcttac tgatttgagt tgcctttcct cgataaggag ttccaccgtc ttctttcata
     1501 cactctggat aaccataaaa tacgatttct tgcttatttt ctggttccat tataagcagt
     1561 tcaggataac ctttttttac cttcactttg ataatcgcta aatctagact atctgagcat
     1621 cttggcggtt ctaagatttc tagttcagat tgggtataat caaacagttt gaagtcatta
     1681 attgtttccc caaccacaca atgttttgcg gtgatcacaa aacccgtttc acaatcctgc
     1741 tgatacaaca aacctgaacc ataagtattg gttcctctaa tattcactga taactcttca
     1801 aaatcattca tatgtcaatc gttagtaccc tctcattcat ttttttcttg atcaattgaa
     1861 tcccgtattt ttttatttct tcatttgtaa ataacccctc actcgcatcg gaataattaa
     1921 aataaaaatt cgttggtcgt ttttttgtgt agttgtggta aacaatcctt gataaggctt
     1981 ctttgtgcgg aaaaccatga cgattcccct tatttgaact aatcaaataa ttttcacact
     2041 caatctgttt taataaatcg tcactagtat tcgctttact cccatgatga gccactttta
     2101 ccaagtcaaa atgcagctct ttttccccat atagttcttt taacttcgca gtgacagtac
     2161 ttggatgagc atctgctaac atcaacagtc gtttgccttc atactccaat ataaagctaa
     2221 tactgctccc atttgcgaca gcgcgatctt cttggaaagc ttttttgatc agttcctcta
     2281 cgcttccctg atgattgaca tttcgaccgc tgatcagttg atccctggtt tctttttgaa
     2341 ttgccttttc ccaatctgta tataatttcc ttagacttgc ttcatcaggt gtcaaaatcg
     2401 tcatttttgc cccattgagt aatttgggct gacaagaatt gtcaataact gtcatctttt
     2461 caatcctcaa attctccaaa taccgatcga aagactcccc ttgtttaaaa ctaatctctg
     2521 acttttcttg aacgatctcc agttgatcat cataaacaac ctttgtatca aacttttgcg
     2581 ataacagctt tctagaatta aaaaacactc gtttaataca tgacttatca aaactcgact
     2641 gagaaaacaa actcaaaaat ccccgaatat gatcggcatc aatatgtgtc aaaaccagta
     2701 agtcaatgca ctcgcctttc tggctaattg ttgcaatttc ctctttcaac tgcctaacaa
     2761 cttgttgtcc ttgacctcca tcgacaaaca gattcgtccg ttgatcttct tctccatact
     2821 gaacaatcaa acaatcgcca tcataagcag gtaaagcttt cactgtaatc atttctcttt
     2881 cattgcagtc ctgtccctgc aatctcctcc ttcttctgct ttcttttcgc tgatcttgtt
     2941 attctttact aaccaaaatc acacacaata aacttctatt catttgttat tggcactgga
     3001 attcagctga caagaagagc tttcagtcca ttagttaatt gcgcgaaata cactcttttc
     3061 tttcttatct tactccccat aacattgtta ttgtaaataa attttgattt ttaaacgcca
     3121 agcattctca taaccagaaa taattgcttg attcataact cgccaaataa ttgagaaggc
     3181 gaccaaaaaa tagcacaagc aaaaaaagcc agcaagacca ttttaaggct tgctgacttc
     3241 aattcttgat tgttaaaatt tagcactata cagacaaatg aagctcaaat gatcactcaa
     3301 ttcccaaaaa atactgactc tcactggttc ttgagttcaa ttaccattgc tttaattcta
     3361 tctcttgttt ttctaaaagc tgatgttatt tctgcttcgg ttccaactgc ttgtgcgggg
     3421 tctgttaaat cccaatgaat gtgctgaaca cctacaggaa tcgtcggaca tttatctttt
     3481 gcatctccac aaagcgtaat aatcaagtct gcttgtgtaa aataatcctg atcgatcaaa
     3541 tcagacgttt ggtttgaaat atcaattcca tcctcagcca taacctgaac cgctcgtgga
     3601 ttcagtccat gagtttcaat acctgcgctt ttaatttcca catccgaggc agataataat
     3661 tgacgtgcat atccttccgc catttggcta cgacaagaat ttcccgtaca taaaaaataa
     3721 atttttttca tttttatttc tcctcctgga tatgagcatt caatatagct cggtcattat
     3781 tttattctct aactaaaagc aagcatacag gaatttttgt aggaaagcat caaaaaagag
     3841 tgaaatgatt gaaaagttac gtcatcaatt atcagtttgg tatgttttgg ccatcagttc
     3901 tgatcttctt tttacctgat aaataataaa tggcattatc catggatcgc ctaaaattga
     3961 agaaaattca tcatattcga tgtcatgaat catttcctaa aagaattttt ttactaacga
     4021 atgctaaatg aacgctttgt tttaaacggt agtttgaaga accttattct attgaaagaa
     4081 gctagaataa ccgtagctat tagcacccca cccataattt cactacattt ggttttatac
     4141 taaaaaaatg aaataaattg attgattgaa cacattgaaa cctaaacttg ttcctttaaa
     4201 cttaaattgt aagcgaagat cgtttacata aattatatta aagggaggaa taccataaaa
     4261 aaaaaattac cattggtcag cctattgttt ggtttcattg ctttaatgtt tttcttacca
     4321 ctaaccaaaa cacatgctga tgtcaccgta acaaacgatt gtacagatcc gtcacattca
     4381 tttacagctt ccattaacgc agataatgga aaagatgtct cgtcagacta ctacaaagta
     4441 acagttggac aaacagaatc ttggcgtaga aatgatccta gaggccatat tttagccatt
     4501 gtttatttag aacaacttag gacctactat actccaacta acgctgccta ctcttttaaa
     4561 gatggaaaac tttattccca aggtagcaca acagaaatca ctccgttaaa agttgaaaca
     4621 aattcgcttg ttacgcgaag catgaacgtt aacatgatta atctttctac aagtcttacg
     4681 acagtatcgt taagtaaatg gaaaagtggc ggatcgacag actactttgc gctaaaccac
     4741 cttgatagtg aaacttggag cagaaatgat gatccaagag gctttttagt ttcagtccta
     4801 tataatggcg gattctcaaa agaatacata tattatttac ctatataaat tgagttaaat
     4861 tgtattcgtt tttcctccta taggcgtata ctaaagaaaa cacttgagga gtggggaaca
     4921 tggaaacaga acgccaaatc cgtgaattgg aaaaagcgat gaatacgaca gacaaccgcc
     4981 ggttgtacga gcgtttcctg gcagtcaagt tggttcttga aggccacacc cggaaagaag
     5041 ccgggcacac catcggccgc gacgagcata ctgtcagcca ctatgtgaaa aactactgcc
     5101 ataatggaat ccaaggttta gtctccaaaa aacaaagcgg acgaccttca cggctgacag
     5161 atgaacagga agcggaactg gtccaaatcg tcgcctacca cactccggag gaagtaggtt
     5221 tcaaatcccg tgccaattgg acattggcga ttgtgtgtga cctgattctc cgggaatgga
     5281 gttatggata tacgcaaaaa ggcgtggcgg acctccttca ccggctagga ctaagctgga
     5341 cccgtccgac gtataccctc aaaaaagcgg attccaagaa acaacaggta tttttggaag
     5401 aaaccttccc gagcctaaaa aaaaattgct gaatagcgat attgaccacc tcctattcga
     5461 ggacgaaacc atgatccggg attaccaagc cattggctgc acctggtttc tccgcggcca
     5521 ccagcgaaaa atccccactt atggacaaca caaaggggta aaattgatag gcaccttgga
     5581 ttatgaaacc ggtcggatca tttgtacaga agaaggggca tacgacgcag cggccttcct
     5641 ccgttttctg gagcggacgt tgcgggaata ccccaccgga aaaatcgtga tggtattgga
     5701 taatgccctt atccaccacg ccaagctgat ccagtctttt cttgaagaaa acgctaggcg
     5761 cctggcact
//
LOCUS       DAIGUC010000102         5466 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.106, whole genome shotgun sequence.
ACCESSION   DAIGUC010000102 DAIGUC010000000
VERSION     DAIGUC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.106"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            118..1107
                     /locus_tag="NOB46_002683"
     CDS             118..1107
                     /locus_tag="NOB46_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI1059581.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="NOB46_002684"
     CDS             1089..1550
                     /locus_tag="NOB46_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI1059582.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLVLMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="NOB46_002685"
     CDS             1600..2064
                     /locus_tag="NOB46_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1059583.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="NOB46_002686"
     CDS             2078..2827
                     /locus_tag="NOB46_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059584.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="NOB46_002687"
     CDS             2827..3657
                     /locus_tag="NOB46_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1059585.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="NOB46_002688"
     CDS             3657..4304
                     /locus_tag="NOB46_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1059586.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="NOB46_002689"
     CDS             complement(4402..5178)
                     /locus_tag="NOB46_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI1059587.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5260..5403
                     /locus_tag="NOB46_002690"
                     /pseudo
     CDS             5260..5403
                     /locus_tag="NOB46_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1871 a          739 c          974 g         1882 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaat tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tatcgtaaag ttatataact ttataatacc tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtattaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattagtttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgtatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttcataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgactcca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgt taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtagat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaataa aagattaaga tataaatata aatgaactag tctttgacta accaatgccc
     5281 gcttttgaaa gaaaacaaat tcattctgtt ttaagtaaaa atccttatgt taccactcat
     5341 tctgaagggg atgagcctta tcgctacttg gttgtggaac caagcgataa gacaatttta
     5401 taaattcaat attaattaaa ataaaaacaa acaaagtaga ttattttact ttgtttgttt
     5461 ttttat
//
LOCUS       DAIGUC010000103         5415 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.107, whole genome shotgun sequence.
ACCESSION   DAIGUC010000103 DAIGUC010000000
VERSION     DAIGUC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.107"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(152..427)
                     /locus_tag="NOB46_002691"
     CDS             complement(152..427)
                     /locus_tag="NOB46_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HCI1059588.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(399..1352)
                     /locus_tag="NOB46_002692"
     CDS             complement(399..1352)
                     /locus_tag="NOB46_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1059589.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1964..3457
                     /locus_tag="NOB46_002693"
     CDS             1964..3457
                     /locus_tag="NOB46_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HCI1059590.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3592..3888
                     /locus_tag="NOB46_002694"
     CDS             3592..3888
                     /locus_tag="NOB46_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI1059591.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            3989..4840
                     /locus_tag="NOB46_002695"
     CDS             3989..4840
                     /locus_tag="NOB46_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059592.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            4861..5144
                     /locus_tag="NOB46_002696"
                     /pseudo
     CDS             4861..5144
                     /locus_tag="NOB46_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1864 a          834 c         1009 g         1708 t
ORIGIN      
        1 atttagtata gtaaaaacta gaaacaataa aatttgtgaa tgttgtatac ccccaaacaa
       61 tacacatatt ttgaaggatt aggattaata aagctaaaaa tatagtaagt atactaaata
      121 tatttactat atctagtata cttactatat tttaatcttt tgatcgtcta ttatatataa
      181 tccgttcctc gtcgtttaaa gtatcaacat aggcgtccat tgcaagtttg actatttcat
      241 acataggaat atcttttgca taactaagat cccgaatggt ttttagtacg ggaggatcta
      301 cttgaactgg ttttctttct ttcgcagtgt actttcgttc ccctaactcg acattaatat
      361 catctttaat tgaaatatct tcagcaccaa ttttcttctt atctttgttc gttggtaata
      421 atgccattta gtttaatctc ctttccaaga ggtaggatat gattggccat tgagtcagca
      481 tatttaggtg tataatcaaa tccttcaata tcaccatgtt gttcatagta ttcaattctt
      541 tcttctaatt ctgtaaagat gtctgcaaaa atagcccacc atcttcgatc tacataatca
      601 tttaattgga taccattctc accatacatt tctaaccgat ccgagccttt aacaatgctt
      661 ttaaaaatgt ttgattcacc atacttatca attgtttttt gatagtttgc gtgttgagag
      721 gaacgtcgca ctgagaaaag aacaggcaaa attccaatga tttgaagatg agactcttca
      781 aaattcgtga caatcggaac taaaacttta ttaataaaat cttctgttcc ttccattgcg
      841 taccgtttta attcttgcat tgcaataata taatctgcag cagttaagaa tgcacgaacc
      901 acattatctg ttgatggtgg gcagtcgata aagatataat cgaaattttt tctcaattct
      961 tctaaaggtt taatgaaggc caatgatctc ttacgacgat caggatattt ttcggacaag
     1021 tattcattaa gttcttcaga tccaggagag ccagccataa tatataaatg tggacttact
     1081 tgagtaatac ctgaaaccca gtcccctttt ttgattgctg cagacatgga tcgatcaaag
     1141 ctagtaattt gatacgttga tccaatgttg gaagtagtat ttctttgttg gtcataatca
     1201 attagcaaca cgtctttttc aaaaagttga ctagaaacaa tcgctaataa atcattgtct
     1261 gtagtcttac caatgccgcc ttttctacct gtaagcatta caacttttcc tagtttatct
     1321 gatgttttaa atgcagtccg taagttttcc atagttccct ccaatttcct atactaaata
     1381 tatttagtat acttcatata cttaatatat tcgatatatc taatatactc caaattgata
     1441 agaattcaga ctttataagg aatatagtgg atatactaaa tatatttgct atattcagta
     1501 tatcagatat attcaaaatg tcaaaatata tttgtgcgtt ttgcgttgac aatttagagt
     1561 gaaaagaggt aaacttaatt ctatagaaac cacagataat tcactattta caaagtagca
     1621 aaagcagtgg tactctttaa acagaaaaat tacataaaaa aaagagacgg aaataattga
     1681 ttttagcaga atcaattatt tctgaatcac atggttagga catgtgttca cgctcgtctc
     1741 aagaatatgt aagtagctac caactactta tattaaaagt tgatcggata ccttttccga
     1801 ttgcctttat tctaccaaaa aaaggcgagc aactcaacag aagaaagttt atttagtgta
     1861 cttaaattaa atattcttaa acactgaaga gagaacacat actatggctg agattaaagc
     1921 taaactgtgt tctctttttg tttgagaaag gacgttacaa tcgatgttga gcgaaattta
     1981 ttcagctatt cttaaaaacg gcttacgtac atacaaatat cgaaacagca ccatgaaacc
     2041 tgcaggtcat attgattcca gtaggagtgg tgctatcttt gcgtaccgta gcaagcaatt
     2101 aatgaatgtt gggcgtggta tggtcattac ttcggaagaa gctattttag agaacgaaaa
     2161 gaaactaacg cattggacac ctaataccta tcgctttggt acttatgcgg atgattatcg
     2221 aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa atcaacacat ttgtagttga
     2281 tatcgattca aaagagaacc atcaaggcga aattatttta gcctgtttag atcaagtggg
     2341 ctacatgcca acgctaattt tagaatcaga tcatggttat caagtttatt ttgtactaaa
     2401 gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg atcgatgtag caaaaaaaat
     2461 ttcaaaaaca attcgtctac agttggctga aaaattgtcc ggagtggatc taggatgtaa
     2521 ccacttcgga attgctcgat tcccacaaga aaataatatt gtttttaaag aaatgaacta
     2581 tcagtattct tttgctgact ggattcaatg gtcgatgaag cttgaatcag atcaaaaaac
     2641 aaaagaagat cgagaacgaa aactaattgt ctttcctgag aaaaaagaaa ttcgtcaagt
     2701 agatgaaccg tggttcgata tgttacttca taaagcaaac atcgtcggcg gagaaggacg
     2761 tcttggtcga aataatgtga ttttcacgct ttctttagct tattactctt caggttatgc
     2821 attggatact tgcgaataca atatgttcac attcaacgaa cggttacagg aaccgctatc
     2881 tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct ggtaattatc aagcagcaag
     2941 cagagaattc attattgaat tgtgccagca atgggtttca ccaaccttaa aaaataatga
     3001 tctgttcatt caacgacgtg gctggtggaa atttaaaaag ccacgagatc aaagaaaata
     3061 tagtcataaa aatgaatgga aagaagatct attggcttat ctaagcgaaa aaagtcttgc
     3121 tagtgagcct tatttgaacc tgtcaaaaaa agaattggct tcacaactaa cgatgcccaa
     3181 gcgaacactt gataagatct taaatgagtt acgagaggag aataaagtct tctacaaggt
     3241 aacacgagga agaaatggcg gaatgatcat tgcttcagtc aaaacgttgt tcgcgagggt
     3301 tattcaacta agtaaagaaa agagactaga ttattcaaca aggatcacag aggtatttgg
     3361 actcaacgag agcttagtag aagagacatt tagacaatta tcaaccccct tgaaccctct
     3421 taaagaagtg aatctttttg aagtagatac aggttgaaaa ataaaaggtg caaattgccc
     3481 tatacaatat atctatgata cttctgtagg tgttgctccc tttgcctagc tacgtgtagg
     3541 tggtatactt ataactgcgt atgcagtctt atgtatcatg gaggaagttg tatgtcgtta
     3601 aaaaattatg tctattcaca tcctgttaat gtgtttatca ttggtcgttt gggattatct
     3661 gtggaagtgt tctgtgagct ttatggtttt aagcagggga ctttgtcttc ttgggttacc
     3721 agggaaaaaa cagttgcttc tttgccgatt gagtttcttc atgggttgtc cttagcttct
     3781 ggggagacta tggatcaggt atatgattgt ttgtgtgtgt tagagcagga gtatattgag
     3841 tataaaatag ctaacgagtt aagaaaaagg aagaagtata tccagtagta gtttttattt
     3901 acttaaaaaa ttggttcatt gagcaaccta tcgctgctaa agtagcaaag gaaaacgtta
     3961 aaggaaagaa tttagggaag aaatcgaaat gaaatcggac gactggattg aacacacctg
     4021 gcttcctctg aaaagaaata gcaaacgaaa gaaattttgg gtattgcaat tatggccatt
     4081 aggaaaactt tgtagttacg gggcacgact tattcttgat ttaaccgttt actcgattgg
     4141 agtatttgga acggcttatt acttgataaa tgatcccaat aggattgcag catcagacat
     4201 ttttacagtg ctaatgacgt tgatttttgt catgctattg tctattttta ctcaattagt
     4261 catgcaattt accaggcaaa aattaacagc aggaaaactt ttcaaaagcc tattcgattt
     4321 aattgttgta aatgcaattc tagcgacttt aataaaacaa attgaacaat ctggaagaac
     4381 aacaaaagga gtgaaggatt ttttattgac gtttattcac tttgtaaatg gacacatgta
     4441 tttgtttgaa gtgggtatta ttctcttttt tgtcgggtat gtatccacga aacttattaa
     4501 acgttcaatt gaaaaagaaa ttgaaattga cctgattccg acacttcttg gttatgagta
     4561 caatgttgat tttggaagat atgacgaatt gatcaatacg gatatcgttc acacgagtat
     4621 ccatgaatct actgttaagg gcatcagatc tattttaaaa aatggccagg aaatgaaagc
     4681 aatagatcga agaaaagaga tctacaattt ttatgaagtc gaagcaagcc tacgatatgg
     4741 catcggaaaa ttgtggttag atggaagtaa tattcgtcaa aacaaaccat acattttttg
     4801 gaacagtagt gatttagaac ttccaatgaa agataaataa ttatggagaa tcgtttgaaa
     4861 atgattcctc tatacaggat tgtgcttata gttggcatgg agttaaaaac cttaaagaag
     4921 gagcagttat tcaaagtgaa agaacgtcat aatcagttac tatgtagtaa aacgggtacg
     4981 atgaacattg aataccgaac agaatattta gaattaacga atcaaactga ttttttgttg
     5041 attcgaaagc aacaagagca agaaaaaaat taatggctac ttatagccaa ttgattgatg
     5101 aatgggaaca attcaaggaa tctaaaattc cagaacgtct ctaaaagcct ttatttgtaa
     5161 agagcataag gaaacgtggg aacacttttt aaaaaaagtg ttccaatagg ctgtgcctat
     5221 tacgtttctc aaaaataaat gtgggaacaa aatatttaaa aataggatag tgaaaggata
     5281 gtgaaggata gtaaaaggag ggtagtagga tagcaaaaag gataggctcc ttttcgctat
     5341 cctttttaaa ttggaggaat taatatggaa gtaagaataa gaaatgtgga tgagaaaatc
     5401 gtaagagaaa ttgat
//
LOCUS       DAIGUC010000104         5357 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.108, whole genome shotgun sequence.
ACCESSION   DAIGUC010000104 DAIGUC010000000
VERSION     DAIGUC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.108"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            23..694
                     /locus_tag="NOB46_002697"
     CDS             23..694
                     /locus_tag="NOB46_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1059593.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            753..1193
                     /locus_tag="NOB46_002698"
     CDS             753..1193
                     /locus_tag="NOB46_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059594.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1205..1873
                     /locus_tag="NOB46_002699"
     CDS             1205..1873
                     /locus_tag="NOB46_002699"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI1059595.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1937..2560
                     /locus_tag="NOB46_002700"
     CDS             1937..2560
                     /locus_tag="NOB46_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HCI1059596.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2616..3002
                     /locus_tag="NOB46_002701"
     CDS             2616..3002
                     /locus_tag="NOB46_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HCI1059597.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3215..4606
                     /locus_tag="NOB46_002702"
     CDS             3215..4606
                     /locus_tag="NOB46_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCI1059598.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1776 a          883 c         1124 g         1574 t
ORIGIN      
        1 tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata ctctgattga
       61 gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc atttttcacc
      121 agagttccat ctagaggggc taacattagg agaaatctat caagcagaag ggctgtcggc
      181 tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata tcgagctttc
      241 tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa tgatcgatac
      301 aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc gttatcaaat
      361 agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa aaagcttttt
      421 aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga aaaaatatcc
      481 aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc atcgttttat
      541 acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca catttcgagt
      601 agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa atcggaatgt
      661 ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg atttttttgt
      721 cataataaat attagatgat ggaggagata atatgatgca aacatggtta gaaaggctaa
      781 tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa tttgatcagt
      841 tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt tggttgccct
      901 atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt cgtttcctat
      961 caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat cttgatagag
     1021 tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat cgaaaaagtt
     1081 atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa ggaaaaggac
     1141 gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt taagggagaa
     1201 aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg aaaattactg
     1261 gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag cagttgccgg
     1321 tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg ttttgaaacg
     1381 tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc ttcctataat
     1441 aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa acaaagataa
     1501 gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat atacggaagt
     1561 tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg atccgcattt
     1621 gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct tatggcaaga
     1681 tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc atggtaatag
     1741 catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg atacgatcga
     1801 tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa ttctggacaa
     1861 aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag aagcaaagga
     1921 atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat tgtttgatac
     1981 gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta tcagtatgga
     2041 caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga tcaatgaatc
     2101 aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag aaagtacgga
     2161 agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag acaacggcgg
     2221 tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt taaaagaaca
     2281 tcgattggca catctgattg aggaagtagt agggatcgat caggactttc ctcgtaaacc
     2341 tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa cagacacgat
     2401 gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag tcgctacttg
     2461 tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg taggaaatct
     2521 gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt caaaggagat
     2581 atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga caaaaagaag
     2641 ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa acagatttga
     2701 aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa catagcatcg
     2761 taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct ggaagtgtga
     2821 gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc acacaagaag
     2881 aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct tatgaggtga
     2941 cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa aaacaagaat
     3001 agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt ttttattact
     3061 aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa aagtcactga
     3121 aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta cttccttcga
     3181 tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca cagttttagt
     3241 ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc gccatacaaa
     3301 attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg gtctgcttca
     3361 attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga tcgggattgt
     3421 aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt ttatttcgat
     3481 cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta gtgcgactgt
     3541 attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg gttcaacaat
     3601 gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag cacgaatctc
     3661 tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc agattttatc
     3721 ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa gtacgattgg
     3781 agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa gaaaagcgcc
     3841 aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca ttatgcggat
     3901 cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga caaacgtttt
     3961 ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg cttcttacgt
     4021 agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa aagtcaatcc
     4081 aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt cacgttcaag
     4141 tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag tagatgatgc
     4201 aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct gtgctggcgt
     4261 ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg tctttagttt
     4321 ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg tagctggagt
     4381 cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact tgccagtagc
     4441 aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta cagcagtaaa
     4501 cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag atttagatcg
     4561 cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa aaagaggttg
     4621 tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag tttctcaaat
     4681 ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg aataagaggt
     4741 tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata gttcctcata
     4801 ttttacgttt ggttgagctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
     4861 aggtcgtgag cctgccgttt cactctgagt cacaaagagc aatttcaaaa aatagcttct
     4921 catgtttgtt gaatattgtg tcttgtgacc gaggagttgt caggagaaca ccgtttacca
     4981 gaggttgtga cttgttttta gtcacgacct ctttttttat ttattccata taaatacaca
     5041 ttatttattc cgaaaagtga aagcgcaaat aacaaaaaca accaacttat ttattattaa
     5101 agaaaagcgt atttaagtag gacgattctg ttgagagctt tcgtagattt tcccattttc
     5161 ctatggtaaa ctgacaaagt tgagaatgtt agaacagatc gtttagtcta atggtgataa
     5221 gtcaagatga aatttaagat tttctttatt gagtaatatg ttttgaagcg cacgaaacta
     5281 gacccgatca aaatcaaatt tttttcgggt tgattcaagg atttgcgtca ataacggatt
     5341 gttatttctc tatcaca
//
LOCUS       DAIGUC010000105         5030 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.109, whole genome shotgun sequence.
ACCESSION   DAIGUC010000105 DAIGUC010000000
VERSION     DAIGUC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.109"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(142..1086)
                     /locus_tag="NOB46_002703"
     CDS             complement(142..1086)
                     /locus_tag="NOB46_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCI1059599.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDMD
                     KQVTFIEGDVSDSQLMERIMKEYQFAYIFHLAAVASVADSVERPVETHRVNFDSALLL
                     LELARKYQSNLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKAEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILSGMERYLKTEI"
     gene            complement(1220..2611)
                     /locus_tag="NOB46_002704"
     CDS             complement(1220..2611)
                     /locus_tag="NOB46_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HCI1059600.1"
                     /translation="MLNERFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFVINIFIQFS
                     FIALSGSRTTLVCLLITTFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAHAWAHVPHITEVKKDTSDSSGTTSSNKVDLKRPDTDSGDVSNLRFELWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKALRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            2737..3147
                     /gene="tagD"
                     /locus_tag="NOB46_002705"
     CDS             2737..3147
                     /gene="tagD"
                     /locus_tag="NOB46_002705"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HCI1059601.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGHFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            3323..3736
                     /locus_tag="NOB46_002706"
     CDS             3323..3736
                     /locus_tag="NOB46_002706"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059602.1"
                     /translation="MISISHSIKELFTIKDKNIEINSFQETFYKDKKAIVIEGPLVRT
                     FRHCLFCKESAKQIEKNGKKISMIILNRSGNKQTYLRLRKQHYHCQSCGKYFTAHTYL
                     VAPSCFISKQVHYTILEELTERQALKTIAKRCDFQ"
     gene            3893..4150
                     /locus_tag="NOB46_002707"
     CDS             3893..4150
                     /locus_tag="NOB46_002707"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059603.1"
                     /translation="MTFCPAGEKKDLIAYFMRFTRKAHMGVRYIVTDMNAPYFSLVKE
                     PFPNAQIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKCQRHL"
     gene            4237..>5030
                     /gene="istA"
                     /locus_tag="NOB46_002708"
     CDS             4237..>5030
                     /gene="istA"
                     /locus_tag="NOB46_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI1059604.1"
                     /translation="MRKDIREGVMIYVINEIKPNYAALAKQYDCDYRTVKHAYEEAQV
                     KESKPPERKKRPSKLDPYREIIQDKIKDQCSAYSIFKFIEHKGFGGSYSLVKTYCRQI
                     KQAKVHKATVRVEHSPGLSAQVDWKEDMRLISNQGEIFEFNIFLYVLPYSKKKYVTLT
                     FDRKQDTLFECLDDAFYQTGGVPKEIWFDNMKTVVDHSRSQFSKPHFNKRFYAFSKDA
                     GFTPIACRPFRPQTKGCVEALARTVDRLRVYNHEFYDAVELCHLVN"
BASE COUNT         1747 a          908 c          791 g         1584 t
ORIGIN      
        1 aagttctctt tttcatgtaa aatatttaat tatatatttc ctaaataaaa agtaaaacaa
       61 gaattaaata gttggttata caactttaat tcttgtttta ctttttagaa ttatttatcc
      121 aaagatgcaa tcattttttc atcaaatttc tgtctttaaa taccgttcca ttccgctcaa
      181 tatatcaaat ttaggctgat agcctaaaga acgaattttt gaaatatccg ctaaggaatc
      241 acgaatatcc cctgaacgct ccgcttcata tttaagcgct agctctgttc ctaagatttg
      301 atcaattgaa tggatcaatt caagtagcgt agtgcttttt cctgtaccga cattgaattg
      361 ctgtcctaaa gctttttctt ccttggcaac aagtaaaagt gcttgtataa catcttctat
      421 ataaacaaag tctctagact gactcccatc gccaaataaa gtaaattccg ctttttctcc
      481 tgccaattgt tttttgtaac gatccactag aatcgaaatg actccgctat atggagagtt
      541 tggattttga tttggaccat aaacgttaaa aaatcggaca gcactagtcg gaacatcata
      601 taaatgacag taatccaaaa catattgttc tgctgcaaat ttatcgatag catatggtgt
      661 taatggacgg atgactgatt cttctttttt tggcagtgtt ggttcatcac cataaactgc
      721 agctgatgaa ctaaatacta atcgttttaa attagattga tatttccgtg ctaactcaag
      781 caataaaagc gcactgtcaa aatttacacg atgtgtttct acaggccgtt ctacagaatc
      841 tgccacacta gctacagcag ctagatgaaa aatataggca aactgatatt ctttcatgat
      901 tctttccatc aattgagaat ctgatacatc cccctcaatg aaagtcactt gtttatccat
      961 atccaagttt tctttttttc ccattgataa atcgtcaact actacgattt tgttttcttt
     1021 tcccaaataa ttcgctagcg ttgaaccgat aaaaccagct ccgccagtaa tcaatatagt
     1081 gtccatcaaa ttcactccaa ttgcacattt tcgtatcaaa taatattagt ttaccatttt
     1141 tatattgtaa aaactataaa atttgttgaa gttgggataa ctagttttct tttctacttt
     1201 catataccta aaaatagttt caattagtta ctccttcttc tttagatata gttttttgga
     1261 tagaacccag atatccccaa aaaataaatg aacctatcgt actaaccaaa atgagttctg
     1321 tgataaataa tgccgaaact gctattgtaa gaatcattaa aatagcaaaa aagtgcttat
     1381 cttttactag atttggttgt gtgaaacaat aacgcaaggc tttaaagcat tggataaata
     1441 agaaggttaa caatgtcaat agacctaatc ctcctgtagc agccatcact aagaaaataa
     1501 aattatgagc agttaaagta tcttttccca ttaatgtata tggtagttta tcatgtgcat
     1561 attcaatata gtagcctgga gaacctccgg atatcggctt actcttgaat atttcaattg
     1621 cacttttcca aagttcaaac cttaaattag aaacatcccc gctatcagtg tcagggcgtt
     1681 ttaaatcaac tttattgctg ctagttgttc ctgatgaatc agatgtatct ttttttactt
     1741 ctgtaatatg cggaacatgt gcccatgcat gagcagttat atctgttaca taatacatcg
     1801 caattatact tagcaatcct actactaatg cagttagcca tctttttaaa gtattagttt
     1861 taagaaaacg actactataa cttgtaaaga aactaaaaac aaaagttgtt attaataaac
     1921 aaactaatgt ggtgcgtgaa cccgataaag caataaacga gaattgaata aaaatattaa
     1981 ttacaaaaaa tattttaaat agaagattta aatgcttgta agtgaccaaa taatatatag
     2041 caataatgat gacgattaat gatataaccg caccaaaatt tggatctgta tatacaccaa
     2101 ataaacggtt gcctaaccac cctaaacgaa ctgggtaata cttatatttt attggaattt
     2161 ttatgccata ttgaatgaca aaccagtata atgatactaa attagctaaa aaccatacca
     2221 atgaaagtat ccaggtaaat actttgaaaa aaaagttact actatagtct ttgccaaact
     2281 gataaatcat aaagaaaaag attaattgcc acatgattaa cttaatattt tcgctatatc
     2341 catattttaa attcattaaa ctgcttacta gcatcgcgcc aataaaagca attaatagcc
     2401 aatcatattt ttttagattt ttttctctaa atgcaataat tgcatctata atgatcaaga
     2461 caactcccgc tattccagca ggccaaaaaa gtaaagtatc atatctagta ggtaatagta
     2521 aatacgggcc tattgctcgt aacattaaaa taaaaccaaa ataaataaaa taccaacctt
     2581 tcacatattt taaaaatctt tcattcaaca tttttcctcc atccacctat ttctcataaa
     2641 tatttcttat cctttttagg ataaactggt cctttcaatt ctaacaaaaa aatgctaaac
     2701 taacaatgta tattaatgaa tttcgagagg tgaaagatga aaagagtaat tacttacggt
     2761 acctttgatt tgcttcatta cgggcatatc aatttactga aacgagcaaa acaatacgga
     2821 gactatctta ttgttgccct ttctacagat gaattcaatt ggaatgcgaa acaaaaaaaa
     2881 tgttatttta gttatgaaaa aagaaaacag ttacttgaag ctattcgcta cgttgattta
     2941 gttattcctg aagaaaattg ggaacaaaaa gtaaaagata taaaagaata ccatgcagat
     3001 tatttcgtga tgggcgatga ttgggctgga cattttgatg aacttgaaca actaacagat
     3061 gcacaagtga tttatttacc aagaacacct gagatctcta caactcaaat aaagaacgaa
     3121 cttaattctt taaatagtga taaataatat tttttaaaca ataaaagaac aatatatctg
     3181 gataagacgt aaaaaaatgg ctctataatt tctaggactg atagaatttt ctgtcggtcc
     3241 tagatttttt gtaaaaaaaa acagacataa aaaaattccg atagaataga gtcgtctaaa
     3301 acatcaatct gaaaggaagt ttttgatatc catttctcat tctatcaaag agctcttcac
     3361 tattaaagat aaaaatattg aaattaattc ttttcaagaa actttttata aggacaagaa
     3421 agccatcgta atcgaaggtc cattagttcg cacttttaga cattgtctat tttgtaaaga
     3481 atctgcaaag cagatcgaga aaaacggcaa gaagatttca atgattatct taaatcgcag
     3541 tgggaataaa caaacctatt tgcgtcttag aaaacaacat taccactgcc aatcatgcgg
     3601 gaaatatttt actgctcata cgtatcttgt cgctccttca tgttttattt cgaaacaagt
     3661 tcattacacg atattagaag agttgaccga gcgtcaagca ttaaagacaa ttgcgaaacg
     3721 ttgtgatttt cagtaacgac agttcaacgg acattatctg ctctatcggc aacgctgcga
     3781 cagaagctag actatttacc tcattgttta ctattcgacg agtttcgctc tctttcaatt
     3841 ttccatggga agttctcctt ttcttgtatg aattgagaga cagggaagct ctttgacatt
     3901 ttgtccagcc ggagaaaaaa aagatttgat tgcttatttc atgcgtttta caagaaaagc
     3961 tcatatgggg gttcgataca ttgtcacaga tatgaatgcc ccttattttt cattagtcaa
     4021 agaacccttc ccaaatgcac aaatcatcat tgattgcttt cacattgggc aacacttgaa
     4081 caagtttttc gatcgtgttc gaaaacgtgt gatgaagcag ttgaatcaaa aatgtcaacg
     4141 gcacctttaa aatgtaggaa aacggcaatt taaaattgtt ggtttaccta catttttgta
     4201 tgctcttctt atcccaaatg aaatggaggc tcagggatga gaaaagacat acgcgaagga
     4261 gtgatgatct acgtgatcaa tgaaatcaaa cccaattatg ctgcactagc aaaacaatac
     4321 gactgcgact accgaacagt taagcatgct tacgaagaag cccaagttaa agaatcaaaa
     4381 cctccagaac gtaagaagcg tccaagtaag ttagatccct acagagaaat catccaagac
     4441 aaaatcaaag accaatgcag tgcttacagc attttcaagt ttattgagca caaaggattt
     4501 ggaggaagct acagtttagt aaagacctat tgtcgccaga ttaagcaggc gaaagtacac
     4561 aaggcaaccg tccgagtcga acatagccct gggctttctg ctcaggttga ctggaaggaa
     4621 gatatgcgac taatcagtaa tcagggcgaa atttttgagt tcaatatctt tttgtacgtc
     4681 ttgccatatt ccaagaaaaa atatgtcaca ctaactttcg accgaaaaca agacacactc
     4741 tttgagtgct tagatgatgc gttttatcaa accggtggcg ttcccaaaga aatctggttc
     4801 gataatatga agacagtcgt tgaccattct cgtagtcagt tttccaaacc gcatttcaac
     4861 aaacgttttt atgctttcag taaggatgcc ggcttcacac caattgcctg tcggccattt
     4921 cgtccgcaaa caaagggctg tgtcgaagct ttagccagaa ctgttgaccg cctacgggtc
     4981 tataatcatg aattttatga tgccgttgag ctgtgtcatt tagtgaataa
//
LOCUS       DAIGUC010000106         5018 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.110, whole genome shotgun sequence.
ACCESSION   DAIGUC010000106 DAIGUC010000000
VERSION     DAIGUC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.110"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..863
                     /locus_tag="NOB46_002709"
     CDS             <1..863
                     /locus_tag="NOB46_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059605.1"
                     /translation="QGLQKKFGKFQALKDVSFTVNAGEVVGFIGPNGAGKSTTIRTLL
                     GIINRDEGDVQIFGKDVWKDSLEIHKRISYVPGDVALWGSLTGGEIIDLFIKLHGGGS
                     KAKRDYLIKRFELDPKKKAKGYSKGNRQKVGLIAALSVESDLYILDEPTSGLDPLMEA
                     VFQEEVEKIKNDGKAILLSSHILSEVERLADKVAIIRRGEVVETGTLDELRHLTRSTV
                     TLVTEGDIEKLATLSGVHDFVQKDGKATFSADNEAMNTILTEATKLGVTKIESVPPTL
                     EDLFMRHYEG"
     gene            887..2500
                     /locus_tag="NOB46_002710"
     CDS             887..2500
                     /locus_tag="NOB46_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI1059606.1"
                     /translation="MNEKFARWNVLFIQYVKRDWKKIIVWVLGLGLFSGAFVPAFEEI
                     AKGQGLLGMFETMQNPAMISMVGPTPIKIGTDYTLGAMYAQEMLLFCGLFAMIISALH
                     VVSHTRKEEELGLTELVRSFRVGRQANSLAVISEMLLINLLLGLLIGGLMMSFGVKTI
                     DAEGAFLFGGSIALAGIIGGVLALVMSQIMATSTGATGSTLSLIGLLYIVRAGTDVSN
                     LDLSMFNPMGWIYLTYPFTENNWLPLLFALIFSLVFTVLAFVLEEHRDMGAGYLPERE
                     GRATAKKSLLSVPGLFFKINKGVMIGWLIAFVVMGAAYGSIYGDMQVFLGGNELMKQM
                     FTQSGVSIEESFTATIMMVMIGLVTILPIAVVNKLFAEETRLHLSQLYVTKITRGQLY
                     WTTIFLAIFAGVVGIGLASAGLGGTAISAMKNESTMDLTDFLAAGYNFLPSILFYIGL
                     AALALGWLPKFGKVIYAYLGYSFALNYFGGILDLPDWFSKTAIQSWIPRLPMEKFDGT
                     IFAVITVISIVFLFVGYLGYKRRDMVEGA"
     gene            complement(2572..3084)
                     /locus_tag="NOB46_002711"
                     /pseudo
     CDS             complement(2572..3084)
                     /locus_tag="NOB46_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337518.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            3347..3463
                     /locus_tag="NOB46_002712"
     CDS             3347..3463
                     /locus_tag="NOB46_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta-toxin"
                     /protein_id="HCI1059607.1"
                     /translation="MVQNQHQETPEFKAIQQKLESLQPPTPPIPKTPKLPGI"
     gene            complement(3726..4463)
                     /gene="erm(B)"
                     /locus_tag="NOB46_002713"
     CDS             complement(3726..4463)
                     /gene="erm(B)"
                     /locus_tag="NOB46_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI1059608.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(4588..4671)
                     /locus_tag="NOB46_002714"
     CDS             complement(4588..4671)
                     /locus_tag="NOB46_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCI1059609.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
BASE COUNT         1547 a          869 c          992 g         1610 t
ORIGIN      
        1 tacaaggctt gcaaaaaaaa tttggtaaat tccaggcgtt gaaagatgtc tcattcacag
       61 taaacgccgg tgaagttgtt ggttttatcg gaccaaatgg agcaggaaag tcaacgacga
      121 tccgtacact gctaggaatc atcaacagag acgaaggaga tgtccaaata ttcggaaaag
      181 atgtttggaa agatagtcta gaaatccata aacgaatttc gtatgttcct ggagatgttg
      241 ctctttgggg cagcctgact ggtggagaga tcattgatct atttatcaaa cttcatggcg
      301 gcgggagcaa agcaaagcgc gattatttaa tcaaacgatt tgaacttgat ccaaagaaaa
      361 aagccaaagg ttactctaaa ggaaatcgtc aaaaagtcgg tttgattgct gcactttcag
      421 ttgaatctga tctgtatatt ttagatgaac cgacttcagg actagatcca ttgatggaag
      481 cagtattcca agaagaagta gaaaaaatca aaaatgatgg caaagcgatt ctattatctt
      541 cacatatttt aagtgaagtt gaacgattag cagataaagt agcaatcatt cgacgtggag
      601 aagtagttga aacaggtaca ttagatgaat tgcgtcattt gactcgctca acagttacat
      661 tggtgacaga aggcgatatt gagaaacttg cgacgctctc tggcgtgcat gattttgttc
      721 aaaaagacgg caaagcaact ttttctgctg acaatgaagc gatgaatacg attctgaccg
      781 aggcaaccaa attaggtgtg acaaaaatcg aatctgtacc gccaacgctt gaagatctat
      841 tcatgcgtca ttacgaaggc tgattgtcgg aacggaggaa aagaaaatga atgaaaaatt
      901 tgcccgttgg aacgtattgt tcattcaata cgtgaaacgc gattggaaaa aaataattgt
      961 ttgggtttta ggtttgggtt tgttctcagg agcatttgta ccagcatttg aagagattgc
     1021 taaaggacaa ggtcttttag ggatgtttga aacgatgcaa aatccagcga tgatctcgat
     1081 ggttggacct acaccaatca aaataggtac ggattatact ttaggagcga tgtatgctca
     1141 agagatgttg ctgttttgcg gattgttcgc aatgattatc tcagcacttc atgtggtgag
     1201 ccacacgcga aaagaagaag aattaggttt gactgaattg gttcgctcat ttcgagtagg
     1261 acgacaagcc aattcattag ctgttatcag tgagatgctg ttgatcaatc ttttattagg
     1321 tcttttaatc ggcggactca tgatgagttt tggtgtaaaa acgattgatg ccgaaggagc
     1381 tttcttgttc ggaggatcaa ttgcattggc gggaattatc ggtggtgtat tggcacttgt
     1441 gatgtcgcag attatggcga cttctactgg agcaaccggc tcgacattaa gtcttatagg
     1501 acttttgtat atcgtgcgcg ctggaacaga tgtgtctaat cttgatttat caatgttcaa
     1561 tccaatggga tggatttact tgacctatcc tttcacagaa aataactggc taccattatt
     1621 atttgctttg atttttagtc ttgtttttac cgtacttgcg tttgtgttgg aagaacatcg
     1681 cgacatgggc gcaggttatc ttcctgaacg agaaggacgt gcgacggcga agaaatcact
     1741 actttctgta cctggtttgt ttttcaagat taataaagga gtaatgattg gttggctgat
     1801 cgcatttgtc gttatgggag ctgcgtatgg ctccatttat ggagacatgc aagtctttct
     1861 tggcggaaat gaactgatga aacaaatgtt cactcaatct ggcgtttcca ttgaagaatc
     1921 ctttacggca acgatcatga tggtaatgat tggattagtc acaatcttgc caatcgcggt
     1981 ggtcaataaa ttatttgcag aagaaacaag actgcatctg agtcaactgt atgtaacgaa
     2041 gattacgcga ggccaattat attggacaac gatattttta gctatttttg ctggagtcgt
     2101 aggtattggc ttagcatcag cgggattagg tggaacggcg atttctgcga tgaaaaatga
     2161 atcgactatg gatctgaccg atttcttagc tgctggatac aattttctcc cttccatctt
     2221 attttatatt ggtttggctg ctttagcgtt aggctggttg ccaaaatttg gaaaagtaat
     2281 ctatgcttat ctaggctatt cctttgcttt gaattatttc ggcggaatct tagatttgcc
     2341 ggattggttc tcaaaaactg caattcaaag ttggattcca cgcttaccga tggaaaaatt
     2401 tgatggaacg atttttgcag taattactgt tatcagtatc gtcttcttat ttgtcggcta
     2461 tttaggatac aaacgccgtg atatggtaga aggcgcttaa aaattgaatt tctaaaaaac
     2521 cgttcatatt tacgaaagtc gatttgagcg gtttttttat ggcttcaatt gtcaaattaa
     2581 gtgcaacgat tcattaaaaa atacttcata aggggttttc caatttagac atttccgtgg
     2641 tcgcgtgttt aatttattcg cccattcttg aatttgacta tcgaaaatac ctgaaatatc
     2701 ttcacctttg ggtgaatatt ctcgtaataa accattagta ttttcgtttg taccacgttg
     2761 ccatggagca tgtggatctg gaaaatacac tttagtgcca tttaattcta gcgttattcg
     2821 actatgttgg gagaattctt ttcctctatc gggtgtaacg gttttacatt tatcttctcc
     2881 tacatttctt agtagattga tcatacaatc aaccacattt ttagagattt tcttttcaac
     2941 cttaccaagt agggagaaac gagatctacg atcgactaga gttacaatac gagccctacc
     3001 tgttttaccg gctacagtat cagcttccca attaccaatc tcaaggcgct cattggcagc
     3061 agatggcctt tcatggatct tattgtatgc agatgatcca atgacagcta gggcaccacc
     3121 aaaacaagcg catgatattg ttgtcaaaaa cttaccgacc aatttagaaa cccttcataa
     3181 aacgggctta tttagcgata taaggcttta caatagagaa ggagtgaaac tctattcaag
     3241 cttagaaacg ccttccatta gtccgaaaga gaccttagaa agagaattaa atcgtaaagt
     3301 atcagggaaa gaaattcaac cgactttgga gagaatagag caaaaaatgg ttcaaaatca
     3361 acaccaagaa acccctgaat ttaaagcaat tcaacaaaaa ttggaaagct tgcagccacc
     3421 tacaccacca atacccaaaa cacctaaact tccaggtatt taaaccttaa aaaaggaaaa
     3481 gagtagttac caaaaaacgg taactactct ttttttataa aaacatttcc tcatgttggg
     3541 gtcccgagcg cctacgagga atttgtatcg ataagaaata gatttaaaaa tttcgctgtt
     3601 tttttctaat ttcattttga ggtgaattaa ttggtagtta ttagaggtgc cctataccta
     3661 ataatttatc tacattccct ttagtaacgt gtaactttcc aaatttacaa aagcgactca
     3721 tagaattatt tcctcccgtt aaataataga taactattaa aaatagacaa tacttgctca
     3781 taagtaacgg tacttaaatt gtttactttg gcgtgtttca ttgcttgatg aaactgattt
     3841 ttagtaaaca gttgacgata ttctcgattg acccattttg aaacaaagta cgtatatagc
     3901 ttccaatatt tatctggaac atctgtggta tggcgggtaa gttttattaa gacactgttt
     3961 acttttggtt taggatgaaa gcattccgct ggcagcttaa gcaattgctg aatcgagact
     4021 tgagtgtgca agagcaaccc tagtgttcgg tgaatatcca aggtacgctt gtagaatcct
     4081 tcttcaacaa tcagatagat gtcagacgca tggctttcaa aaaccacttt tttaataatt
     4141 tgtgtgctta aatggtaagg aatactccca acaattttat acctctgttt gttagggaat
     4201 tgaaactgta gaatatcttg gtgaattaaa gtgacacgag tattcagttt taatttttct
     4261 gacgataagt tgaatagatg actgtctaat tcaatagacg ttacctgttt acttatttta
     4321 gccagtttcg tcgttaaatg ccctttacct gttccaattt cgtaaacggt atcggtttct
     4381 tttaaattca attgttttat tatttggttg agtacttttt cactcgttaa aaagttttga
     4441 gaatatttta tatttttgtt catgtaatca ctcctgaagt gattacatct ataaacaaat
     4501 acagaagtta aacgatttgt ttgtaatttt agttatctgt ttaaaaagtc ataagattag
     4561 tcactggtag gaattaatct aacgtattta tttatctgcg taatcactgt ttttagtctg
     4621 tttcaaaaca gtagatgttt tatctacata acgcatttgg aataccaaca tgacgaatcc
     4681 ctccttctta attacaaatt tttagcatct aatttaactt caattcctat tatacaaaat
     4741 ttttaatgca ctatcaacac actcttaagt ttgcttctaa gtcttatttc cataacttta
     4801 gggttaacca tacgcaagac caatcactct cggacaatac tcatgatttt aatgataaaa
     4861 tccatgttaa acccatagat aagaaataca cctgcaataa ccgttacctg tttgtgccaa
     4921 tttaaaaatg caccactttt ttataattaa aacggttgaa aactgtacca ctaataactc
     4981 acaatagaga gatgtcaccg tcaagttaaa tgtacaaa
//
LOCUS       DAIGUC010000107         4953 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.111, whole genome shotgun sequence.
ACCESSION   DAIGUC010000107 DAIGUC010000000
VERSION     DAIGUC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.111"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(148..1110)
                     /locus_tag="NOB46_002715"
     CDS             complement(148..1110)
                     /locus_tag="NOB46_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI1059610.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1112..2551)
                     /locus_tag="NOB46_002716"
     CDS             complement(1112..2551)
                     /locus_tag="NOB46_002716"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI1059611.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNKNWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2736..4682
                     /locus_tag="NOB46_002717"
     CDS             2736..4682
                     /locus_tag="NOB46_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HCI1059612.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1603 a          824 c          803 g         1723 t
ORIGIN      
        1 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacaagttga
       61 caactccttt ttgtttacaa atcaattgga tatctacaaa ttgtattttc taacgaattt
      121 tatagacatt aaaaaattaa tttaacgtta aatacttcct ccagaaagta ttgagattgg
      181 taaaatataa tccttatttg tcttttcgcc tttaattttt ttcagaagaa tatcaacaat
      241 aagacttgca atttcatcaa ttggttgtct tattgttgtc aattgtggga aaaatttctc
      301 aataaaagag gtaccatcgt atccaataat ttttaaatct tctgggatat taagtttaag
      361 ttgatgagca attttcatag tgagaatggc tgttaaatca tcagaaacaa aaataccatc
      421 tggtttgtga tttataatag ttgactttat ttccatttca cgacggatag tagacagatt
      481 attaggaatt ttgaaaattt ttccatttgg attttgaaaa gaaaaaccta gtgcacgtaa
      541 ttctgtggga gaatccgtgt tatcatttcc tgtaatcata atggtatttt gacaaccatt
      601 tttttgtaaa gtcttagctg caagttttcc cccttcaaag ttatctgaag aaacaatgga
      661 aacattagga gctaaatttc tatcaaaagc aacaataggt gctctcacac gctcataatc
      721 agcaattcca agattatggc ttgatgagat tatgccatca acttggttgg cttcaagcat
      781 ttcaatgtat tctctctctt tagcaggatc attttgacta ttgcaaataa tcgttttata
      841 tccatgttta aataactcta tttcgagata ctcaatgagt tcagagtaaa agatattact
      901 aatattagga aaaataagac caataagctg aggtgacttt ccttgaagtc cacgtgctaa
      961 attatttggt ttataaccaa gagttttcat agcttcatga actttttgtt ttgttttttc
     1021 tgataaatat cccttattat taatgacgcg tgaaacggtt gttgggctaa ctccagctaa
     1081 ttcagcgaca tcagttaatt ttgctaccat tttaatattt taattcaaag tattttccag
     1141 taggttcgcc tgatttgatt tgaataccat tttggtgatt ttcagggaat acacgactag
     1201 taaacacttt ttctccttta ttaataaaaa tctcaatgat tgagttatct acaaaaatgt
     1261 tagcagttgt ttctttagta tcaattgagc attcacgaat cgtaccaaag tcagtggcat
     1321 attgaatgcc tgctttgctg cgatctaaaa taatttttcc ttctttggta tctacaatca
     1381 agctaagtcc atttccttta ctatcagaga aaagaagtaa ctccgatttc tgatttggag
     1441 gaaaagttag ttcaagctca taagtattat ttgtttctgc ttttgctgta aattgttcag
     1501 aactagcacg taatgatgta atagcttcta ctggatattg gtaaagttta ccatctttta
     1561 ttgaaagttc ttttacaaga ctcattgctc cctgataatc atacttatca gttggataat
     1621 cgatatcagg tagtccaatc caactgacaa tcagagcacg accatcagga gtattgaatc
     1681 cttgagtcgc atacgcttca aatccataat caagattttg aatttctgaa gcgcccacaa
     1741 gttttacttt ttctatgtca agcgattgac agatcttaaa agtattcgga tagatattcc
     1801 cataatttag ctcagattta tccaaccctt gaggacaata aatgagaaca ggttttttgt
     1861 ctacaaatac tagatttgga cactcaatca tgtattctga accagtgccg ccaaaatcaa
     1921 ggttgccaac ttcctcccat gtttccacgt tattgtcatc cgctttgtaa agtttgataa
     1981 agcctgattt ttctaaattt tgtgctccaa caatcgcata caattgtcct tcataattaa
     2041 acatttgtgg atcacgaaaa tgatcagtta catcagcagg tttatgaata agaacattct
     2101 cacctttcgt aatgttgtag tctttatcca tccatgctcc gatttgaagt gtatcacgtt
     2161 cccaattttt atttcgaacg tttcctgtat agagtaagaa tagattcccc tctatttcat
     2221 atgcagaacc ggaataagcg ccgtggctat ctcgttttgt gtctggaaga agttctgctc
     2281 ctgttacatg aaaatgaact aaatcatctg attcattgtg tacccattct ttcaacccat
     2341 gagcagctcc aaatggccaa ttttgataaa aaagcgtata ttttccgtta aaaaaagaaa
     2401 aaccattagg atcgtttaac aatcctgttt taggttcgat atgatagcta gcacgccaag
     2461 gtgatcgttt tacattatcc ttaattttat ccatctcatc tttagtccaa tcagaataag
     2521 cacgatatcg tatttctcga ggtaagttca tattttactc cttcaattta tctttttaca
     2581 actagtatgg taaacgtttt ccgttgaaaa atcaatcatt tcatttaaaa aaataaacta
     2641 tatgacaaac gtttgacata tttttaagat atgctaaaat aaatttgcat ttcagtgaac
     2701 cgttttcacg taaaaataaa aaaggagtga ttcgaatgaa ttacagtaaa gtagcttccg
     2761 acgtaataca agcggtcgga aaagataacc ttattgcagc tgcacactgc gctacacgtc
     2821 ttcgtctcgt actaaaagat gacacgaaag tgaatcaaaa agctttagac gaaaatccag
     2881 atgtgaaagg cacatttaaa attgatggac aatatcaagt gattatcggt gcaggtgatg
     2941 ttaatttcgt ttatgacgaa cttatcaaaa aaactggact ttcggaaatt tcaacagatg
     3001 atttaaaaca aattgctagt aaagataaaa aattcaaccc cattatggca ttaattaaat
     3061 tattatcaga tatttttgtt ccaattatac ctgcccttgt tgcaggtggt ttattaatgg
     3121 cattacaaaa ctttttaaca gctgctggac tttttggacc aaaatcaatt gaagaaatgt
     3181 atcctgcgat tgaaggtatt tcctcaatga tccaactgat gtccgctgca ccattcatgt
     3241 tcttaccaat tttagtaggt atttcagctg ctaaacgttt tggagcaaac caatttcttg
     3301 gtgctgcaat tggtatgatc atgacaacac cagatcttgg tggctcaact gaatattgga
     3361 atatttttgg ttatcatgtt tcacaaacaa actatgctta tcaagttatt ccagttttag
     3421 cagctgtttg gatattatct atattagaaa aattctttca taaaaaattg ccatcatcta
     3481 ttgactttac attcacgcca ttattatcag taatgattac tggatttttg actttcacag
     3541 ttattggccc tgtaatgtta ttgttgtcta atggaattac agacattatt gtttggctat
     3601 ataacactac tggatttatt ggaatgggta tttttggagg aacatattca cttatagtca
     3661 tgactggttt acatcaatca tttccagcta ttgaaactca attactttca gcgtggacaa
     3721 atggtatcgg acatggagac tttatctttg tagttgcatc tatggcaaac gttgctcaag
     3781 gtgctgcaac atttgccatt tggttcttaa ctaaaaattc taagacaaaa agtcttgctt
     3841 cctctgcggg tgtctcagca cttcttggaa ttacagagcc tgccttgttc ggagttaact
     3901 taaaataccg ctttccattc ttttgtgctt taattggttc aggaattgct acagcagtag
     3961 caggattact taaagtagtt gctgtttcac ttggttcagc aggtttcttg ggatttcttt
     4021 caattaatgc aacatctatt ccattttacg tattgtgtga attgattagc tttgtagttg
     4081 cttttgcaat tacttacttc tacggtaaaa caaaagctgc tggtatcttt aaagcagaag
     4141 aaattgctga acaaacacca gttaattctt caaaagtagc aacaacagat ccaatatcta
     4201 ctgatgttga atcaacacaa acaaaagttt catcagaaac aattgttagt cccatttctg
     4261 gtaaagtgat tagtctttct tcagtaaatg atccagtctt ttcatcagaa gctatgggaa
     4321 aagggattgc cattaaacca aatggaaaca cggtccattc tccagtagat ggtactattc
     4381 aactcacgtt tgaaactgga catgcttatg gtattaaatc aaataatggt gctgaagttc
     4441 taattcatat tggtattgat actgtatcaa tgggaggaaa aggatttaca caaaaagtta
     4501 ctactaatca aaaagttaga aaaggcgata ttcttggagc atttgaccgt tcaatgattg
     4561 agaaagaagg tcttgatgat acaacaatga ttattgtgac caatacttcg gattattcag
     4621 aagtaaatat agtagctgaa aatacagtca ctgagggtac tgatttactt gaaatcaaat
     4681 aaatatattt ccctgagtaa agatggaatt ttctttccaa aatcaaataa tatagattaa
     4741 tcaaatattt gagaataaca ttttatttaa tcttttcata tatcaattgt atgaaaaatt
     4801 attagaattt taaaaaatga taaaaattca aaaagaaaaa atagtagtta tttacttgtc
     4861 atgttactaa ataaaaaaat aatttaaata tgatatatag tcatttattt agtgatttca
     4921 ttctaaaata aagggagaaa tgtctatgct ata
//
LOCUS       DAIGUC010000108         4930 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.112, whole genome shotgun sequence.
ACCESSION   DAIGUC010000108 DAIGUC010000000
VERSION     DAIGUC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.112"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            84..971
                     /locus_tag="NOB46_002718"
     CDS             84..971
                     /locus_tag="NOB46_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI1059613.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1111..2037
                     /gene="cysK"
                     /locus_tag="NOB46_002719"
     CDS             1111..2037
                     /gene="cysK"
                     /locus_tag="NOB46_002719"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCI1059614.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2273..2719
                     /locus_tag="NOB46_002720"
     CDS             2273..2719
                     /locus_tag="NOB46_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI1059615.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2992..4344
                     /locus_tag="NOB46_002721"
     CDS             2992..4344
                     /locus_tag="NOB46_002721"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HCI1059616.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4515..4802
                     /locus_tag="NOB46_002722"
     CDS             4515..4802
                     /locus_tag="NOB46_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059617.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1694 a          813 c         1030 g         1393 t
ORIGIN      
        1 attaaaagta taatttaatt aattaagttt gttttaagaa gagaactttt tattaagttt
       61 ttttattttg aggaggaatt tgaatgcaag agctgaagac ccgcagtgcc cggcaccata
      121 gacctaaaag aaaaatggtg atcaataaaa aagcgattgc tcctttaatt ggaacgagtc
      181 ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca gatgaacaag
      241 gatctcaaac agtcgctgat cctcaagcgt ttatcgatca aatcggctgg tctgcgtcag
      301 aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg ttgttggaaa
      361 gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc ggtgtgaaag
      421 gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaaac ggacaatggg
      481 taacgatgaa tgagccattc cgaaaatatt cttcttattg ggaatccttc caagaccatg
      541 cgaatgttct tcgttcaacc agtttttcca cgggcgatta tcattatgct ggcgtgtgga
      601 aaagcaatac aacaagtttt tatgatgcaa cagcgtactt gacaggtcgt tatgctaccg
      661 atccaaatta tggggccaaa ttgaactcat tgattaatac ttataattta acccgttttg
      721 atacgccatc aacaggttcg gctacaacaa ccacaagtac aacaacaacg actactacga
      781 cgacttcaac gtcatcatct tcaacaacag atgtaaatac aaataatggt cagacatata
      841 cagtcgtgtc aggtgatacg ctatgggata ttgcacaaaa atttggcatg tctgttgatg
      901 atctaatggc gaaaaatggc atgtctatgt ccagttattc tttattagtt ggtcaagaac
      961 taaacgtttg atttagataa aaaggcaaag aaattaccat atatggtata tctttgtctt
     1021 ttttttgcta gtcaaagacg aatcactcgc cataaatgaa cagattgtat tatgataagt
     1081 aagaagagca aagacaagga ggaattgaag atgacagcta tctataactc agtcaccgaa
     1141 ttgattggca aaacgccaat cgtcaaatta aataaaatcg taccagaaga ttcagcagat
     1201 gtttttgtaa agcttgagtt ttttaatcca ggaggaagtg taaaagatcg tattgcttta
     1261 agtatgatag aaaaagcaga acacgatggt ctactgaaac caggtgatac tatcattgaa
     1321 cctacttctg gaaatacagg aatcggattg tcgatggtag gagttgcaaa aggatataaa
     1381 gtaatcatcg tgatgcctga gacgatgagt atcgaaagac gtttattgat gaaagggtac
     1441 ggcgcagagt tgattttgac tcctggtgcg gatggtattt ctggatcaat cagagaagca
     1501 gaacgtttgg caaaagaaaa cggctacttt ttaccattac aatttgaaaa tgaagcaaat
     1561 cctcttgtgc atgagaagac gactggtcct gagatacatc aagcatttgg agtaaatggc
     1621 ttggacgcgt ttgttgcagg tatcggtaca ggaggaacga tcactggcgc tggccgagaa
     1681 ttaaaacgtg tgtatccgaa aatcgaatta atcggggtag aaccagcaga atctgctatt
     1741 ttagaaggga aagaagcggg acctcacaaa atccaaggaa tcggtacagg ttttgttcct
     1801 aaaacactgg atacttctgt gtatgataaa gtcctttcta ttagtggaga cgaagcgatg
     1861 gaaacagcta gagaagttgg gcgaaaagaa gggattttag taggcatctc atctggcgct
     1921 gcaattgctg ccgcgctaaa agtcgcaaaa gaattaggaa aaggcaagaa ggtattagct
     1981 gtggttcccg acaatggtga acgttattta tctacagccc tttaccaaga gatataaggc
     2041 acttggtttt tctccagata ggtttatgta aaaaactttt aaagatgaaa agaacacaca
     2101 aaaatttatg atgagaaaaa ttatttgaat agagacgtag aatagtgaac gcgactgttt
     2161 tacgtctttt ttcattaaaa tacaataaaa ttgaattttc ttttcatgtt aagtggattt
     2221 taaaatgtaa aaatagtatg ataagacgag aataacaacg tggggtgttt acatggaaaa
     2281 taagttagtc gaagaggtta tcgaaaagtt aaaaaaagag aacattcgaa tcacacctca
     2341 acggtacgcg gttttagaat atttgattga acatcattcc catccaacgg ctgatgagat
     2401 ttataaagca cttgaacatc ggtttccaaa tatgagtgtt gcgactgttt acaataacct
     2461 tcgcttattt acttcgattg gatttgttca agaaatgaag tacggcgatg cttctagccg
     2521 atttgatttc agttcaaagc gtcattatca tgtaatttgt gaaaactgcg gtaagattgt
     2581 tgattttcat tacccagggc ttgaagatat agaaatggct gcaagcagac tgactgattt
     2641 tgagattaat gaacatcggt tggaattgta tggactctgt ccggattgta aagagtcagc
     2701 aaaaaaggcg caaatgtaaa aacagtttct acaagtgtta tacctaaaaa aagctagctg
     2761 tgtaaaaaaa acgctagctt ttttattttt ttgtctttta ttcacaatct tagatataaa
     2821 agtgaatatt attaaaataa gaatcttgta gatattgggt tcttatgctt gaaaaggaat
     2881 gaaactacaa acaaaccttt gtgaattcac aagcattaaa ctgttgtatc cgttttattt
     2941 ctgttatagt agttttgtcg aaggacaaaa tgttaatcgg agggaccata aatgaaagta
     3001 gtagtaattg gctgtactca tgcaggtact gcagctgtaa aaagtatttt aaaaaatcat
     3061 ccagaagcag aagtgacagt atatgaaaga aatgacaata tttctttctt atcttgcggt
     3121 atcgcacttt atgtcggcgg agtagtaaag gacccagcag gcttgttcta ctcaaatcct
     3181 gaagaattat cttcattagg agcaacagtt aaaatggaac acgatgtaac agacgtcgat
     3241 acagaaaata aaacagtaac ggcaaaagat ctgaaaacag gagaaacaga aacggtttct
     3301 tatgataaat tagtgatgac aactggttca tggcctatta tcccaccgat tagtggaatc
     3361 gatgcgaaaa atgtactcct atgcaaaaac tacaatcaag caaatgaaat tattgcacaa
     3421 gcgaaagaag caaaacgtgt agtaattgtt ggtggtggat atatcggtat tgaattagta
     3481 gaagcttttg tcgaatctgg aaaacaagtg acattgattg atggattaga tcgcatcttg
     3541 aataaatatc tagataaacc attcacagat atcttagaaa aagaattgac agaccgcggt
     3601 gttactcttg cgctaggcga aaatgttact gaatttatca cagatgaaga aggaaaagtg
     3661 aaacaagtag ctacaccaac agatacattt gatacagata tggtcatttt atgtgtgggc
     3721 ttccgtccaa atacaaaact gatcgaagga aaagtagata cactgccaaa cggggcaatc
     3781 aaagtgaatg aatacatgca gacaagtaat ccagacattt ttgcagctgg agactctgca
     3841 gtagtcaact acaatccaag tggcacgcaa aactatattc ctttggcaac aaatgccgtt
     3901 cgtcaaggtt tgcttgtggg aaataacttg acagatcata aaatggcgta tcgtggtact
     3961 caaggaactt caggacttta cctatttggc tggacgatcg gttcgacagg tgtgaccaaa
     4021 gaaagcgcaa ctttgaacga tctagaagtc caagcgactg tatttgaaga taattatcgt
     4081 ccagagttca tgccaactac tgaaaaagta atgatggagc tagtctatga aaaaggaacg
     4141 aatcgtatcg taggtgctca gttcatgtcc aaatacgaca ttacacaatc agcaaatacc
     4201 atgtctttag ctgttcaaaa taaaatgact gtagaagatc tcgcactttc agatttcttc
     4261 ttccaaccac attttgaccg cccatggaat tacttgaacc tacttgcaca agcagcgcta
     4321 ggcgaaatcg aaactgcaca ataaagaaaa agggttgtga cacaattttg tcacgaccct
     4381 ctgtcttttt ttgtgaaaag tacaattagt tgtctttctt cgaatttttt gtcacaataa
     4441 gcagcaaaga taaagctgtt acataaaaga acaagcagct ttatttgatt ttgaaaagaa
     4501 aggtgagaaa gaagatgaat aaagaatatt ttgtccaaca agatgcattt ttagaagatt
     4561 ataaaagtgc ttcgaagaaa ttaacgatca atattgatga gttggcagat caagtactct
     4621 ctcagttgaa tgaaacgcaa gaggaatatt acacgatgcc agcaaatgac gccaaagata
     4681 atgtttctca tcgttttcct ttcagtagac gcatctactc agatgaaaat gacggcacat
     4741 tgaatacaga gtacacatat gaaggtcagc catatgtgct agaaactgat gatgatcttt
     4801 aaagacagtt tttgaaaagg ccgctcatcc ttaagtgatg acaaaaaatc atcacaatta
     4861 ccgatgactg tctctttact atcttttaat cagaaaaagg ggttatgaca agctttgtca
     4921 accccttttt
//
LOCUS       DAIGUC010000109         4909 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.113, whole genome shotgun sequence.
ACCESSION   DAIGUC010000109 DAIGUC010000000
VERSION     DAIGUC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.113"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..183
                     /locus_tag="NOB46_002723"
     CDS             <1..183
                     /locus_tag="NOB46_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI1059618.1"
                     /translation="QRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLS
                     RTQRRFEGTLRYSLGY"
     gene            270..1124
                     /locus_tag="NOB46_002724"
     CDS             270..1124
                     /locus_tag="NOB46_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI1059619.1"
                     /translation="MENSLYLVKEPNTHLRDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINEQKYYLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGELVEYY
                     LKEIGVGKENLTFKVENLNSFKGIIFETLSYDQDNLISELSRQTQVYKFLELLLNSAS
                     YLKEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKSDMGISI
                     KEYISEIKLSIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGAYRKRRL
                     GLGIINGE"
     gene            1221..3470
                     /locus_tag="NOB46_002725"
     CDS             1221..3470
                     /locus_tag="NOB46_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI1059620.1"
                     /translation="MYKNNEMNIIYRSENQQFHLFNQEISYIFKISDDGKLLHLYYGE
                     NLPDNDYTHLIEMHHRPMTTYRKENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLTDFIYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3473..4648
                     /locus_tag="NOB46_002726"
     CDS             3473..4648
                     /locus_tag="NOB46_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1059621.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4651..>4909)
                     /locus_tag="NOB46_002727"
     CDS             complement(4651..>4909)
                     /locus_tag="NOB46_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI1059622.1"
                     /translation="GITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQN
                     FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1706 a          714 c          898 g         1591 t
ORIGIN      
        1 caaagaaaaa cagttgagac tgttttttct tccttagaaa aattaggttg tcaaaatttc
       61 aactcacgtt ctgttaaagg gctagagagt agatttgaaa gcatattact ggcttacagt
      121 gttctattaa gtcgaacaca acgacgtttt gaaggaactt tgagatattc tttaggatat
      181 taaaattaac tagcaccacg ggtgatatta tgtaataata taaacatgat gaaacaaaaa
      241 ttatccaaat ctaacttagg aggactaata tggaaaattc tctatattta gtgaaagagc
      301 ctaataccca tttgagagat tgttacttta atttttgtgg atactcaaaa acagaaccta
      361 gacatagttt tggaccagct attcgagaac agtacttaat acacatagtc ttagaaggtg
      421 aaggttatta ttcaattaat gaacaaaaat actatctgaa aaaaggacaa ggttttgtga
      481 ttccaccagg agtatctact ttctatcaag cagatgaaaa aaatccttgg tcgtatgtat
      541 ggttgggatt aagtggagaa cttgtagaat actatctaaa agaaatcggt gttggaaagg
      601 agaatcttac ctttaaagtc gaaaacttaa attcttttaa aggaataatc tttgaaactt
      661 tatcttatga tcaggataat ctaattagtg aattatccag acaaacacaa gtttataaat
      721 ttttagaact cctcttgaac tcagcgagtt atttgaagga agggataatt actaaaaaga
      781 tgaatccttt tgttcgtcaa acaattgaaa taatacgtga gaatgcgtat caaaaattat
      841 ctgttaaaga tattgctgtc agtctatcga tacacgaaaa ttatttatca cgattgttta
      901 agagtgatat gggaatatca ataaaagagt atatcagtga aattaagctt tcgattgcaa
      961 atgacctact atcatcaact gaatattcaa ttcagcaaat cagtgataag ataggattct
     1021 caacagttca atctttttct aaagctttca agaaggccaa tggtgtttca cccggggcgt
     1081 atcgaaaacg taggttaggt ctaggaatca ttaatggtga ataaactaaa catttgattt
     1141 tgataaatat tcgttacttt aaacgcttac tatttatgta agcgtttttt ataatgcaat
     1201 aaagaagtgg aggagagcgt atgtataaga ataatgaaat gaatattatt tatcgatcag
     1261 aaaatcaaca atttcatttg tttaatcagg agataagtta catttttaaa atatcggatg
     1321 atggtaaatt actgcattta tattatggtg agaacttacc agacaacgat tatactcatc
     1381 taattgagat gcaccatcga cctatgacta cttatagaaa ggaaaacgat ttattatact
     1441 ccctagagca cttgaaacaa gaatttcctg aatatggtac aacagatttt agacatcctg
     1501 ccatttcact actacagaaa aatggctctc gtctaacaga ttttatctat caagggtacg
     1561 aagtggaaga aggaaaacca aaattagaag gtttacctgc tacctatgtt gataataatg
     1621 atgaaagcaa aacattgaaa gtttatattt tagattcagt tacaaatgtt caagtagaat
     1681 tattatatac aatttataga gattatcctg ttattactcg tagcgcgcga gttatgaata
     1741 aaggaaaaga tattcaaata atcgagaata ttagcagttt atcattggat ttacccgatg
     1801 caaattatga atggcaacaa ttatctggtg cttggggtag agaaagaact attaagtcgc
     1861 gtactttaca acaaggaatt caatcaatcg aatctactcg aggtatttca agccatcagc
     1921 ataacccatt tgttacttta aaaagaaaaa atactgatga aaatcaagga gaagctattg
     1981 gtgcagcact agtttactca ggaaacttct taattcaagc agaagtagat acatgggatg
     2041 ttactagact acaagttggc atcaatccat ttggatttaa ttggaaactc aatccaggag
     2101 aaatatttac agcaccagaa gcgattctgg tttattcaag taagggttta aatgccatga
     2161 gtcaaacttt tcatcaacta tttagaaaac gcttagctcg tggtaagtgg cgagaaaaag
     2221 accgtcctgt cttaattaat aattgggaag caacatattt tgattttgac gaagaaaagt
     2281 tggtaaatat tgctaaaaaa gcatttgatg ttggtattga attatttgta ttagatgatg
     2341 gctggtttgg agaaagagaa aacgattgtg caggattagg agattggcat gtaaatccta
     2401 aaagactacc tagaggaatc ggcagccttt cagaaaaaat tcgtagtttt ggtatgaaat
     2461 ttggtttatg gtttgaacct gaaatggtga ataaggatag tgagttatat cgcacacatc
     2521 cgaattggat tatttctaca cctaatcgaa aacctaatca tggtaggaac caatatgtat
     2581 taaattttgg gttagatgag gttgttgaaa atattttcga tcaaatgtgt aaaatcattg
     2641 atgaatcaaa cttagattac attaagtggg atatgaatcg tccattgact gatgtatttg
     2701 acagtcactt gtcagcagat caacaaggag aagtattcca cagatatgta ctaggcgtat
     2761 atcgcttata tgaaaaactt ataacaaaat atcctaacat actatttgag tcttgttcat
     2821 caggtggtgg gcgctttgat cctggaatgc ttcactatgc acctcaagct tgggctagtg
     2881 atgattcaga tgcaattgaa aggttaaaaa ttcaatatgg aactagtatg ctgtatcctc
     2941 tttcgtctat tggtgctcat gtatcaattg ttccaaatca tcaaacaaac cgtataacac
     3001 ctataaaaac tagaggaaat gtagcttttt ttggtgcatt tggatatgag cttgacttaa
     3061 atgaattaag tgaaggcgat ttgaggattg taaaagaaca aattgccttt tataaaaaat
     3121 atagaaccat aattcataat ggtacttttt atagactatt atcaccattc gatgatgata
     3181 atcaaaccgc gtggatggtt gttagtcatg ataagaaaac ggctattgtt gctcattata
     3241 aaacattaaa tgaggtaaat gctccttacc gccgactgaa attaaaaggg ttagataatg
     3301 acggacttta taatgtagga caaaatagtt tgcgatctgg aatggaattg atgagagcag
     3361 gactagtctg ttcagatgca tctagtggac aaataaatga tcagaatcga cgcccagaaa
     3421 catttgattt tgattccaag atttgggtta taacacagga ggaaaagtag agatgaataa
     3481 ccaaaaaagc ttacttcaaa aaggagcaat cttaagtatt tcactaatgt taacaagctc
     3541 tcaagcaatt aatggtgtta ttccacaaat gaaacagtct ttggggatat cacaaagtca
     3601 aagtgaactt ttaggaactg caccaagtat aactgttatt ttgtttatct tattatctag
     3661 ttactttgcc aaaagaatag gaatgaaaaa gacaataatt ttaggtttat tattagctgg
     3721 tataggagga attattccag tatttacagc taccttccaa accgttctta ttagtcgagt
     3781 aatattaggt gccggtttag gagtatataa ttcattggct gtgacatata tcagctcttt
     3841 atactctggc aatactagag caacgctatt aggtattaga aattcaatgg aagctttagg
     3901 tcagacaatc cttatttttc ttgctggagt tttagtgaac attaattgga cggcttcgtt
     3961 tttagtctat gcaattgcgt ttcctgtagc tctcttattc gcgctaaaag ttcctgaaat
     4021 tagagatgaa aatagtgaca tacctgaaaa tcatgtaaaa gaaaagatga atccaatggt
     4081 ttttgcccta gttctatttg caatcttact cgtaatgaat agtattgcta tttctgtacg
     4141 atttgcatca attgcaactg aaattaaagg ggtaaacttt aatgctagta actatttagc
     4201 tctaatgcct atcttaggaa tactagcagg atttatgttt ggaccaataa ataagtggat
     4261 aggaaaagga accctatact tgggaattat attctttata atttcaaatt tgttaattgc
     4321 tgtgtcaaac ggtaatatga cgttcctgct aacgggttta tttttatcaa gtataacagg
     4381 atcatggtgc ttcccattta tctttagtaa cttagataaa gtcactacaa agaatacaat
     4441 taattttgct acttcattga tttttattgg ctgtaatatt ggtaatttta tagctcctat
     4501 tgctatgcaa ttagcacaat ttctaacaag aagtacaaat ttgactgctc cattttttgt
     4561 attcgcagga atatttattg tgatcctatt tgtaacattt tttgcgacaa ataaaaaaaa
     4621 tactagagta acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
     4681 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
     4741 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttctaa
     4801 ggaagaaaaa acagtctcaa ctgtttttct ttgttttcca agtaagctgt ggtctagttt
     4861 ttctgattta tccatgtttt tacgtggcgg aacggatata gtaatgccc
//
LOCUS       DAIGUC010000110         4866 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.114, whole genome shotgun sequence.
ACCESSION   DAIGUC010000110 DAIGUC010000000
VERSION     DAIGUC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.114"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            164..715
                     /locus_tag="NOB46_002728"
     CDS             164..715
                     /locus_tag="NOB46_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HCI1059623.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1391..1645
                     /locus_tag="NOB46_002729"
                     /pseudo
     CDS             1391..1645
                     /locus_tag="NOB46_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1715..2227
                     /locus_tag="NOB46_002730"
     CDS             1715..2227
                     /locus_tag="NOB46_002730"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059624.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2224..3261
                     /locus_tag="NOB46_002731"
     CDS             2224..3261
                     /locus_tag="NOB46_002731"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI1059625.1"
                     /translation="MISFSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
     gene            3421..3597
                     /locus_tag="NOB46_002732"
                     /pseudo
     CDS             3421..3597
                     /locus_tag="NOB46_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            3652..4866
                     /gene="aph(2'')-I"
                     /locus_tag="NOB46_002733"
                     /pseudo
     CDS             3652..4866
                     /gene="aph(2'')-I"
                     /locus_tag="NOB46_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
BASE COUNT         1840 a          719 c          932 g         1375 t
ORIGIN      
        1 aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc
       61 ccagcttaaa tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga
      121 accgaagagc gagcaagaca ggaacgagag aacaaacata ctcatgaaaa gactagaggc
      181 ttcgacctcg aactttaata ataagttaga tgtttttgaa gaaaagacta agcatgcaag
      241 attaaacttt gaaacaactg caaagcacta tattaaacga cttgatgaag ataatttgaa
      301 attagatttt caacaagcta ttcaagatga attaagcgat actaaagacg aaatacgtga
      361 agtgacgaaa caagcgagag aagaaacaaa agagtataaa gaaatcttag aaagtaaaat
      421 aaaagaccat aacaaagtgg ttgataaatc gaatacagcg ctaaaagtga tgacaaaagg
      481 cgttacaaat atattttttg tgctaattat ttttgtactt gtaatgcttg tgacaggtcc
      541 gataggtcat ttctttggta ttgaacattt atatagcttt attaatggtt ttattgatga
      601 ccacgaaagt gcatggcgat atttgatgtt gatactttat gcagtaccct atgtattctt
      661 cgctatcatt ctgtggctca tagcattgtt ttttagagta tttaatgacc tttaggtaga
      721 tttatatata aaaagggcta aatacgcaaa ataccccctt aaaatgcaaa ataaatgcaa
      781 ataagggggt aactccttat gaaaaaacaa ctaatagtat tataacacgt ttttatgccg
      841 agaaaactta ttggttggaa tgggctatgt gttagctaac ttgttagcga gttggttgga
      901 cttgaattgg gattaatccc aagaaagtac caactcaaca acacataaag ccctgtaggt
      961 tccgaccaat aaggaaattg gaataaagca acgaaaggag ttgagtaaaa tgagtgagaa
     1021 aacgaagaaa atcattcgag tatcattagc tttttcacaa gtagtagtgc aatcattgat
     1081 agtttattat acttaccagc aatataaatt atctaaagag aattaagttt tgattatgta
     1141 ataagttttg gtactaaaaa agacttgatc taattagacc aagtcttttg ttagtgttat
     1201 attaataaca aaataaaaat aagaagtcgc tcactccccg accaaagttt gtgagcaaaa
     1261 taaacagtcg atgtttgttt cttaattgta tatcttgata ttaaacgatt taagattatt
     1321 cttcaagata tatattcgca aatgtaattg gaaaagcgac ttcttaaaca aaattaagga
     1381 gtcgcttttt atggcaaaaa taacgaaaaa tgagcaagaa aatttggtgg aaaattacac
     1441 aaaaaaaccg gcgtactcta atagccggtt agacgcacat ttcgtgtgca cttctaatcc
     1501 gaaattgagc tttgacgcta tgacgatagt cggaaacctt aataaaaaca gcgctaaaaa
     1561 gctatccgat tttatgagtt tagatccaca aattagactt tgggatatac ttcaaacaaa
     1621 atttaaagct aaagcactac aagaccccct atgttaggct agttgtcgta taggataata
     1681 agttataata aagactatac ggaggatgat taccatgaca aataaaaaca atgaacgtta
     1741 ctctaccgaa ctgaaagcga cagccatcaa gaaaatgatg ccacccgaaa atagggggat
     1801 tcgccaatta agtcaaactt tgggcattcc agaagcgact ctttgttctt ggcgtaaaaa
     1861 agctagaatt caagggaata ctacacccgg aacgaaaaaa aatgtcgaaa aatggtcaag
     1921 tgaagataaa tttttaattg tgatggaatc attctcaatg aaccaagtag aacttgcgga
     1981 atattgccga aagaagggct tatttaaaga acaaattgag gcttggaaga aaacgtgctt
     2041 atctgcgaat gaacaggaag aaaatcgaac gagagaactt gcaactgaac taaaagaaga
     2101 gaaaaaacaa gcgcgtcaat tagagaaaga attacgtcat aaggaaaaag cattagcgga
     2161 agccgctgct ctcttattac taagaaaaaa agcacacgcg atttgggggg accaagagga
     2221 agaatgattt cattttcaga tcgcaaacaa gctgttgaac ttattcaaga agccaatcgc
     2281 aatggggccc gtctcaccta tgcctgtaat gagctgaata ttagcgttcg aacctacgaa
     2341 cgatggacgc gtgaaggtac gatagcgcat gatcaacgcc ctttggcgaa acgtcctgta
     2401 cccaaaaata aactgacgga tcaagaacgc gaaaaaataa tagaaaccgt ttcaaaaaaa
     2461 gaatttatga atttgccacc tagccaaatt gtaccaaaac ttgcggattg ctcgatttat
     2521 attgcatcag agtctagctt ctatcgtgta ttgcgagaaa aaaatatgca acatcaccgt
     2581 ggccgaagtc aagtttcaca aaaacgcata ccgccaagtc accttgcgac gaagccaaat
     2641 gaagtttgga cttgggatat tacttggcta aaaggtccaa taaaaggact cttttaccgg
     2701 ttatatctca tcattgattt atttagccgt aaaatggtag gctgggagat ttgggaatca
     2761 gaagaagctc gtcatgccga aaaacttatt aaacagacgg tgcttaagga acgtatccaa
     2821 ggacagccgt tggttttaca ctccgataat ggcagcccta tgaaagccgc gacttttcaa
     2881 gtcttactcg aaaaattagg aattcaaagt tcttattcaa gaccacgagt gagtaatgac
     2941 aatccttatt cggaagcggc tttccgaacg ttaaaatatc gaccagaata tcccaataac
     3001 ggctttaaaa caatagatga tgctcgaaaa tggacgaaag agtttgtcga ttggtataac
     3061 gattctcatt tgcatagtgg gattcaattt gtgtctcctg cagcgtgtca tgaaggacga
     3121 catctcgcta ttttagagaa acgaaagcag gtttacgagg acgctaaaaa gcgccatcct
     3181 gaacgctggt caaaaggtgt tcgaaattgg actccacatc aatcggtggc gttgaatcct
     3241 ttaaaagaaa cagaaagtta acaggagcat aatctttcaa gattatcaaa taaccctcgt
     3301 cacccaatag gggaaaaagt tattcttccc ctattggata acgaggccaa ccgaccatag
     3361 ggaggttctg ctttttgata ggtggaaaat aaaaatacga caactatatt gacaaacacc
     3421 gaccatcgtc cagtaaagag acgcaataaa ttctatcgaa gtttacgcac tgcctctaca
     3481 acgattaaag gcatggaagc catccgagga ttatataaga aaacccgaaa agaaggcact
     3541 ctcttcgggt tttcggtctg tactgaaatc aaggtattat tgggaatccc agcttaaatc
     3601 atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac cgaatcatta
     3661 aaaaaacatt atacagagcc ttgggaagat gaagttttta gagtaattat tgaatataac
     3721 aatgttccta ttggatatgg acaaatatat aaaatgtatg atgagttata tactgattat
     3781 cattatccaa aaactgatga gatagtctat ggtatggatc aatttatagg agagccaaat
     3841 tattggagta aaggaattgg tacaagatat attaaattga tttttgaatt tttgaaaaaa
     3901 gaaagaaatg ctaatgcagt tattttagac cctcataaaa ataatccaag agcaataagg
     3961 gcataccaaa aatctggttt tagaattatt gaagatttgc cagaacatga attacacgag
     4021 ggcaaaaaag aagattgtta tttaatggaa tatagatatg atgataatgc cacaaatgtt
     4081 aaggcaatga aatatttaat tgagcattac tttgataatt tcaaagtaga tagtattgaa
     4141 ataatcggta gtggttatga tagtgtggca tatttagtta ataatgaata catttttaaa
     4201 acaaaattta gtactaataa gaaaaaaggt tatgcaaaag aaaaagcaat atataatttt
     4261 ttaaatacaa atttagaaac taatgtaaaa attcctaata ttgaatattc gtatattagt
     4321 gatgaattat ctatactagg ttataaagaa attaaaggaa cttttttaac accagaaatt
     4381 tattctacta tgtcagaaga agaacaaaat ttgttaaaac gagatattgc cagtttttta
     4441 agacaaatgc acggtttaga ttatacagat attagtgaat gtactattga taataaacaa
     4501 aatgtattag aagagtatat attgttgcgt gaaactattt ataatgattt aactgatata
     4561 gaaaaagatt atatagaaag ttttatggaa agactaaatg caacaacagt ttttgagggt
     4621 aaaaagtgtt tatgccataa tgattttagt tgtaatcatc tattgttaga tggcaataat
     4681 agattaactg gaataattga ttttggagat tctggaatta tagatgaata ttgtgatttt
     4741 atatacttac ttgaagatag tgaagaagaa ataggaacaa attttggaga agatatatta
     4801 agaatgtatg gaaatataga tattgagaaa gcaaaagaat atcaagatat agttgaagaa
     4861 tattat
//
LOCUS       DAIGUC010000111         4803 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.115, whole genome shotgun sequence.
ACCESSION   DAIGUC010000111 DAIGUC010000000
VERSION     DAIGUC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.115"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            5..862
                     /locus_tag="NOB46_002734"
     CDS             5..862
                     /locus_tag="NOB46_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI1059626.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQRRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            884..1393
                     /locus_tag="NOB46_002735"
     CDS             884..1393
                     /locus_tag="NOB46_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI1059627.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1430..1831
                     /locus_tag="NOB46_002736"
     CDS             1430..1831
                     /locus_tag="NOB46_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059628.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1943..2296
                     /locus_tag="NOB46_002737"
     CDS             1943..2296
                     /locus_tag="NOB46_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059629.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2330..2773
                     /locus_tag="NOB46_002738"
     CDS             2330..2773
                     /locus_tag="NOB46_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI1059630.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2790..3875
                     /gene="uxuA"
                     /locus_tag="NOB46_002739"
     CDS             2790..3875
                     /gene="uxuA"
                     /locus_tag="NOB46_002739"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI1059631.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3868..4581
                     /locus_tag="NOB46_002740"
     CDS             3868..4581
                     /locus_tag="NOB46_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI1059632.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         1659 a          734 c         1083 g         1327 t
ORIGIN      
        1 ggaaatggct gaaataatgg ataatcaaac aggtgctcct gaagaaatca cgaaaaaaga
       61 tgtaacaaaa gcctatctga gatggcattt tgcaaacgaa attcctcact cttttgaacg
      121 ttacttggcg ccatcactac tatacggaat gatgccaatc ttgaaaaaac tttataaaga
      181 tgaagactct ttaaaagcag catataaacg gcagttactg ttcttcaaca ctcaattaag
      241 ctggggtggc ggtgtgatta ctggcctaat gtcttctatg gaacagcgaa gagcagaaga
      301 agagtatgaa gaaaaagaga tcttgatgca ggatgacttg atgtataaca cgaaagcggg
      361 attgatgggg gcactagcag gaatcggaga tgcaatcgat tcaggaaccg tccaatatat
      421 ttttatcgca atcgcggtac cttgggcaca acagggaagt cctttaggcg cactttttcc
      481 ttttatctgc tttgggttgt atcaggtttt actaggggta tttttcgcaa gacaagcttt
      541 cactatgggc cgtaatgcta caggcctaat gcaaaacact ggtgttcaga cagcgattga
      601 aatgctatca gttttagggt tgtttatgat gggggtgctt gcgggaaact atgtaaaagt
      661 agaatcttca ttgaaatttg cgatatccgg acgtgagttt gttatccagg aaattcttga
      721 tcaaatcgtg ccagggatat tacctttagc tgtcgtaatg ggtgtgtact tgttctatac
      781 gaaaaaagga ttgaaagtca cacaagcatt attatggctg actggaatat taattgtgct
      841 agcaggaatc ggtattttat aaaaagaagg gaacgtgaat aagatgggtg tagtcaattt
      901 agcgcgtgtg gatgagcgtt tgatccatgg gcaagtaatg gtaacgttat ctcaaaaaag
      961 tggagtgaat tccatttttg ttgtagacga agttgtagca aaagataaat ttatgagaga
     1021 tctttacaaa aatgcaggaa gccgtacagg acaaaaaaca attgtcatta caccagagaa
     1081 agctaaattc tattgggatg aatatcaatt taaagaatac aattgtattt tgatcgcaaa
     1141 aacagtccaa acgatttacg acttagtaaa acacggaatc cccatggaag aattgaatat
     1201 tggagggatt gctcaaaaaa atcctgatac agatctttta gtgacgaaat ctgtttattt
     1261 aaataaatca gatgctgaaa aattgaaaga aatgaatgaa caatatggcg taaagaatat
     1321 ttattttcaa gccactccat ctgcacctaa aacaggatta aaagatgtat tgaacaagtt
     1381 tgatttgtca taaacaaatg cttagaaaaa agataaagag ggcgaaaaaa tgaagaagaa
     1441 cgagctgttt cgtgattggg aatttcgtta tcgctatatt taccgtaagc gccgtacaaa
     1501 aaagagtaaa cagcgttttc tttcagcatt agtatcagat atttacagta tgagaacaga
     1561 tgtgacagtc attgcttacg atacgctagc ctaccgatca aaaaatattt atgttggaga
     1621 tatcgaaaaa gcagagaaag ttatctgtac ttattacgat acacccgttc atgcattagg
     1681 aagttatttc atgtttgatt ggaaagacca aaggaaaaaa acaatctact ctatattatt
     1741 gtccttcatt ttgttgttca gtttaggttg gtggggaatg atgatatata acaaaaatcc
     1801 tcatcacgta ttcgatctgc tatccgtata aacaggtatc actgtactag catttgggag
     1861 ctactttttc ttattgggaa aagcagctcg cggatggcct agcagacaaa cttttattcg
     1921 aaatacttca tccatattaa cgatgctaga aatgatccgt acgattgatg atccgagtgt
     1981 agcgtatgcg tttgttgatg aaggctgtta tggagaaaag ggcttagaca gcgtgagatc
     2041 gggtatgaaa aaagaggcta ttctttttta tctagactct gttggggcag atacaccgct
     2101 acagttttcg ggaaattatt tttcaaataa agaacagtgg ctgaaacaag ttgataagtt
     2161 gaaagaaaaa aacgtcaatt atatttttag tgcaagaaaa aagcaagcgc agttcttcta
     2221 tttgaccaaa acagatttac gagggaaaac atttaattgg caaaatgcca atcagattat
     2281 tgctcttttt cgataagtaa aaagtgcaaa acaaggagtg agaagactaa tgttggaaat
     2341 catgatcgtt acacatggta agttgagcga aggactgaaa gatgcggcgg aagtaattgt
     2401 cgggacatcg agccatattg aaacaatgtg cttagagtct ggggaggaca tccaaacatt
     2461 cggagagaag gtcaaagaaa aattaactat gatcaacaca gcagaaccca tgctagtatt
     2521 tgttgatcta attagcgcaa gtccgtacaa tcaagcgctc ttggcagtca atgaactgac
     2581 tgaagaaaag aaagcagcca cttatgtcat agggggcgtg aatctgccaa tgttgttaga
     2641 agcaatcaat catcagatgc ttcacacacc gatagaagaa gcggtggaac aaattgtcaa
     2701 acaaggaaaa gataatttaa ctgtttggca tgcttcagcg gaagaaaaaa aattagatga
     2761 ggacgatttt tagaaggaag gctgaaaaga tgaagtgggg atttagatgg tatggtgaaa
     2821 aaggggattc gatcccatta aaatatgttc gccaaatacc gggaataaat gggataattg
     2881 gaactttgct gactaaaatg cctggagatg tttgggagat ttcagaaatt gaggagttga
     2941 aagcatctgt tgagagccaa ggactggaac tgcttggaat tgaaagtgta gcgatccacg
     3001 atgcaatcaa ggcagggaca gatgaacgag attactatat tgataactat atacgaacaa
     3061 tcaaaaactt gtctcgatgt ggggttcgat tgatttgtta tagcttcaaa ccaatttttg
     3121 gatgggcgaa aactgatttg tttaatgaaa acaacgatgg aagctattct cttttatacg
     3181 atcagaaaat cgtcgatcag atggagccag gagaaatgta tcaattgata cacagccagt
     3241 caaagggatt caaattgccg ggttgggaag aagaacggtt gaaaaaattc gctcagctgg
     3301 aaaaactgta tgaaggaatg accgaagaag aattatttga aaatctgact tattttttag
     3361 aaaaagtgat tccagtgtgc gaaaaagcag atgtaaaaat ggctatccat ccagatgatc
     3421 cgccatggga actttttggt tttcctagag tgacgaaaaa tcttggcgac ttgaagaaaa
     3481 ttctaaatgc agtagattct ccatataatg gactaacgct gtgcacagga tctttagggg
     3541 caaatccgga aaacgattta gttgaaatca tccatgaggt aggttcgcgc atccattttg
     3601 tccacttcag aaacgtggag tttttaggag aaagaaagtt caaagaaacg gcacatccct
     3661 ctacagaagg ctcccttgat atgtatcata ttatgaaagc gttggtgcaa gaagggttcg
     3721 acggtcctat acgccctgat catggtagaa ccgtgtgggg tgaagtggct atgcctggat
     3781 atggcctgta tgatcgtgca atgggactca cttacatgca aggtctatat gaggcgataa
     3841 gtaaggaaaa accactggga gagcattatg aataaaatca agctcttcat ctttgatatg
     3901 gatggccttt tattagaaac tggacgttta gcttatcgtg cttatgtaaa atcagcacaa
     3961 aagtatgatt atgaaatgcg taaggaagtc tattatttac taactggcca aacagaaatg
     4021 gcgataagag aacaaatggg cattttgtac ggagaagatg ttccatatat caaatggcga
     4081 gaagcaatca atcaatataa agaaaaaatc gtgaaagaag ataagagagt atatacgaaa
     4141 aaaggagcag aagaaatttt atcttttgca aaagaaagag gaatccatac aatcgtggct
     4201 tcgtctaata cacgggtaaa agtagaaatg tatttaaaaa tggaaaatct atatgccttg
     4261 tttgatcaaa tcatttcagg ggatgatgta aaaaaaggaa agccggaacc agagatcttt
     4321 ttgaaagctt gttcaaaaat gaatattcct ccaagtgaag cacttgtatt tgaagactcg
     4381 attgcaggga tcgaagcagc aaggcgagcg ggcattttgt cttttctcat caaagatcat
     4441 ttgatagggt tgcccgatca taatgggaag cataagttga aagtagatgt aagtttatat
     4501 gaatccaata aagcagacta tgaattttat gacctgcatc aagcaaaacg atttttagaa
     4561 agtaaagggt tgtatctcta ataaagagga ctattttcta gtcctcttta tttattgtcc
     4621 tgcacgactg agggaacaga tgaaaaagaa gtaatttttt attttgaagt atctacctta
     4681 tttgtagtga acaatttaga acaaacacaa aacgcatcta ctgttatcta ccagtagatg
     4741 cgtttaaaga gaagaacgag aatcgtccat atgagggttt ccactcctta tgcagatttt
     4801 ttt
//
LOCUS       DAIGUC010000112         4788 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.116, whole genome shotgun sequence.
ACCESSION   DAIGUC010000112 DAIGUC010000000
VERSION     DAIGUC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.116"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            564..989
                     /locus_tag="NOB46_002741"
     CDS             564..989
                     /locus_tag="NOB46_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059633.1"
                     /translation="MICKNKKKIIAIIASFSLIFSTACTVLLTNNANVEAASSSYKHN
                     HAGYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPGIISLVFGSAVSA
                     NNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            1019..1183
                     /locus_tag="NOB46_002742"
     CDS             1019..1183
                     /locus_tag="NOB46_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059634.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
     gene            2141..3118
                     /locus_tag="NOB46_002743"
     CDS             2141..3118
                     /locus_tag="NOB46_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1059635.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     YFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQNKALELVNQQIYSEKDPTSLQEKIKEQKRKLELL
                     QQLEELERKQNNLNKENKEINEQIPDNNSDIPPELKKGLLDNLQNLFKE"
     gene            3128..3625
                     /locus_tag="NOB46_002744"
     CDS             3128..3625
                     /locus_tag="NOB46_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059636.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNIIYLKKE
                     AVTTITKVLSGNEPGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQLALETQ
                     QKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQSKTEKKW
                     WQFWQ"
     gene            4001..4282
                     /locus_tag="NOB46_002745"
     CDS             4001..4282
                     /locus_tag="NOB46_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059637.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
     gene            4284..4700
                     /locus_tag="NOB46_002746"
     CDS             4284..4700
                     /locus_tag="NOB46_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059638.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPATNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1757 a          817 c          786 g         1428 t
ORIGIN      
        1 aaaaaaaaaa gaaaaatccg cttctgcgaa ttcttctttt ttcattttgg ggcgctgccc
       61 taatccctaa gtcccggtta ttcaatagca tggaaactca aagaataaga cgttccctgg
      121 aataaaaaaa aggctgctcg ttcgagcagt ccatacatag gaaaatgaaa aaacgacgtc
      181 ccttactgag aaacgctatt aaacttttaa caaatcctct aaaaaataac aagtctttaa
      241 aaagtgaccg gtaaaaatgc acaaagaact aaaaaagaga aattgcatca aatcaagcat
      301 tagaagctag taactagcta gaccaattga aaatcacaaa gtgagcgcct gtatctattg
      361 ctacaggcgc tacttggcat agtcgacatt atgtcaacaa gaatttaata taacatattt
      421 ttctagtttg ttataacaat gccactctaa caaaaatgta agcattatcc ttattaaaag
      481 ctccttgaca aggactatac cttttatttt atgattttta catagaaaac gttttctcta
      541 ttttttgttt agaggtgatt tttatgattt gcaagaacaa gaaaaaaatt attgctatta
      601 ttgctagttt ctctttgatt tttagtactg catgtactgt cttattaaca aataatgcta
      661 atgttgaagc tgcaagctct tcttacaaac ataatcatgc tggttataga tgttacaaaa
      721 tgagttatta tgtaagtcct tctaaatgca aacaattggc tcgccaaact aataaactta
      781 ataccgtctc agctattgca aactttattg gactatctgg attaacaccg gggattatat
      841 cattagtttt cggatcagca gttagtgcta ataatgtatt tgttacagcc gctagaagag
      901 gaaaaggcgt tcaattaaat tatattgccc attttagtaa taccactacc tataattata
      961 gttctaacca aaattatgtt ataaaataat taaaacttta aactaggagg aatgctttat
     1021 gaaattaaca aaaattgctg taattttagc tgttattgct ggcattattt tatattttgt
     1081 attgcctgct aatcaattct tcctttactt tggaatacct gcgattttaa tagtaaatgg
     1141 cgtaagaatc tttgaacaac gaaaaaaatg tagctctacc taatcgttac aaaacaacaa
     1201 tttcaccttc ggtgaaataa gcgaaacttt acaaaaagtg gctagcaaat gctagccttt
     1261 tttgtattgt agagcgtgaa ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1321 aagcggttat ttgcaccaaa tacctccgta tttggctagc aatccttcta aaaaatacac
     1381 ctatcgatca gagtcaaaac aaatcaattt tcgagtgagc gaatccgaat ttgcaaagct
     1441 gaagctttgc aaatgagtgt gccggcttcc gtaaaaatac atatggctat aatttgcgtt
     1501 ttaaggcgtt ttaaacgttc tggtatataa ttataccaaa acaactttaa aacgccttag
     1561 atctaatttt agaggtctta tagaacattt tagggttgtt agggcttgcc ctgaccgcct
     1621 gtaaggcgct ttgagaacaa gataagggtt ttatactaag actgtcttaa aacggcttaa
     1681 acaaacgctc agaacttttc aaaggagttc tttatgaact gtttttaagc aaaggagcct
     1741 ttaggcgact gcgcagtata atgtgagagc gtagcgatca cacattttta gtgaccgtag
     1801 ggagcgagtt tcccagttta gaaaaattcg cgaacttgtt tgaggaaaaa agcaggagtt
     1861 ttttaggcgg gaaattttgc ctcctctttt ataatctctt tttaaacctc tttttaaacc
     1921 tctttaccgt cggctgtatg cttactctcc caaggtgtgc agaatctttt gggggtcttt
     1981 ttgtctgttt ttaggggtct ttttgtctgt ttttaggggt ctttttgtct gtttttgggg
     2041 gtctttttgt ctgtttttag gggtctttaa ttaggggctt gacccctatt agaaagctct
     2101 ttataatttt gttaagtagt taatcttgaa ggaggatttt atggcaaatg aaattgtgaa
     2161 ataccaccat gaattaaata cgattccttt acgcaaattt acgtcagtag aaatgaattt
     2221 attcttctct atagtatcta gaatgcgtga cgtaggcgat aaaaaagtac aatttacatt
     2281 cgaacaatta aaagatttaa gcaattataa agcaactgca aatgttcgat tcatagatga
     2341 tttagaaaca acgtatgaca aattaatgga tttacgtttt ggtagaagaa gtgctgacgg
     2401 tttgcaacgt gaacgatttg ttttatttaa tcaatttaaa atcgatggaa aagctgatat
     2461 tccttttgct gaaatacaag tccatgagaa agccttaccc ttacttaata atcttgaaga
     2521 atgggttcga tattctctcc aacaattcaa tgaattagaa agcagttatt ccaaaaccat
     2581 gtttagatta ttaaaacaat acagaaccaa aggaattgcc tatttttcaa aagaagactt
     2641 tcatgaatta cttgatatcc ctaaaagtta tagagaaagt gatataaata aaaaaattat
     2701 aaagcctatt cgccaagaac taaccgcaat cttcaaaggt ctgacaatca aaaagaaata
     2761 cggaaaagga agaggaaaac ctgtcattgg ctatcaattc acgtttaaac ctgaaataaa
     2821 aaaagcagac gactttaata aacacgcacc aacaaaagaa gaacaaaata aagctttaga
     2881 actagttaat caacaaattt actctgaaaa agaccccact tcattacaag aaaaaatcaa
     2941 agaacagaaa cgaaaattag aacttttaca acaattagaa gagctagaaa gaaaacaaaa
     3001 taatctgaat aaagaaaata aggagattaa cgaacaaata ccagataaca attccgatat
     3061 tcccccagaa ttaaaaaaag gcttactaga taatcttcaa aacttattta aagaataagg
     3121 ggtttttatg acagataaaa ctatcaaaga attagcagat attctaggtg tttcaaaaga
     3181 taaagtgaag tatcaactga ggaaattacc tagtaatttt acctacaaaa aaggaaatat
     3241 tatctacctg aaaaaagaag cagtaacaac aattacaaag gttttatcag gtaatgagcc
     3301 gggtaactta cctagtgaat tacctgattc attacctacc gattacctac tcaaggagat
     3361 tgaaactaag aataatcata ttgaagaaaa agataggcaa attgaaaaac ttcaactagc
     3421 tttagaaaca caacaaaaat tactcgacca gcaacaacaa ctcaccctgc aagccaacca
     3481 acaaatcgag aaactgcagg aacaactaca gttgacttat acggaagaat cttcggaaaa
     3541 taaatcaacg actctttctg aagaaacaga atcgatagaa aaacaatcaa agacggagaa
     3601 aaaatggtgg caattctggc aataaaacca gcaatttaaa ttaataaaaa ttgctggttt
     3661 tattcttctt tttgcttttg cgagcagagc aacatgggcc catgttgcga tattttggtg
     3721 gcgccccaat ccccgttttt tcgttgaatc ttactcggac tgcactcgtt ttacagctga
     3781 tttttctgaa ttttgaaaga gcataaggaa acgtggtatc actttcttac gaaaggtgct
     3841 agataagctg tgcctatcac gtttctcaga aaaaaatttg ctatcacttt tttgccattg
     3901 tggctaggct atgtatagtg ttttggcgaa aaatagctat acaaatacta tatttgtatg
     3961 atatacataa attatatact gatacgaaag gaaaatttcc atggacattt tagttcgaaa
     4021 tatcaatccc aaaattatta caagaataga taaacgttgt caggaactaa caaccaaaac
     4081 gggcaaaaaa tggagtcgaa atcaatacct aaaaatttta atcgaaaacg attttgacca
     4141 cgaacttatg aattacaaaa aagatcaatt cgatttatta ttcgaaaaat ttattgccat
     4201 tcaagcagaa aatacgaaca tactaaatga ctatgttcac acaaacaacc aactcattga
     4261 aacacttatc ggaggaatat aacatgagaa aaacttctgt tcaaaaacac gtaacccttt
     4321 atcccagtca cgttgacgtt ttagattcca tcatcgaaaa aaatccagac gtcaacaatt
     4381 attcagaagc cattcgcttt ttatgtatga gttatgaacc tgctaccaat acaaccacaa
     4441 ccagtaacca agcaaaactc aatgccatgg gaaaagaaat ttctatcatg acagaaatca
     4501 tggcagaatt tgctgattta tatctaaaag atactggtgt tcttatcggt acaaattcta
     4561 aagtatatca agaagtgaaa gaaaaaattg aaaatcaact caatccttcc cgacgaaatc
     4621 aacccaaaaa tcgtcaaaaa gaaaccaatc aaacctttac ttctggaaat tttgacccaa
     4681 caaactttct aaaaagataa aaaaagaaac cgaaaaataa aaaaattcct cgatttcttt
     4741 ttagggatcg gtcttccagc aagatttgca agttggtacc aacttgcg
//
LOCUS       DAIGUC010000113         4528 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.117, whole genome shotgun sequence.
ACCESSION   DAIGUC010000113 DAIGUC010000000
VERSION     DAIGUC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.117"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..437)
                     /locus_tag="NOB46_002747"
     CDS             complement(<1..437)
                     /locus_tag="NOB46_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1059639.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAVRIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVY"
     gene            751..1173
                     /locus_tag="NOB46_002748"
     CDS             751..1173
                     /locus_tag="NOB46_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059640.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1183..1386
                     /locus_tag="NOB46_002749"
     CDS             1183..1386
                     /locus_tag="NOB46_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059641.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            1716..2333
                     /locus_tag="NOB46_002750"
                     /pseudo
     CDS             1716..2333
                     /locus_tag="NOB46_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            2507..2716
                     /locus_tag="NOB46_002751"
     CDS             2507..2716
                     /locus_tag="NOB46_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059642.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            2923..3123
                     /locus_tag="NOB46_002752"
                     /pseudo
     CDS             2923..3123
                     /locus_tag="NOB46_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3223..4524)
                     /locus_tag="NOB46_002753"
     CDS             complement(3223..4524)
                     /locus_tag="NOB46_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059643.1"
                     /translation="MENSAFIMKLNDILSPIAAKIGNQRHLKAISSGMMFGLPFIVIG
                     SFFLIFANPPINIDKYNPDTANIFMKFMASWKDFAVANYDLITAPYNLTMGIIGFISV
                     FGIAFSLANEYKINPSMNGMVASVIYLMVCTPVEEGAINLNFLGTNGLFVAIIIGLLV
                     VEINRLFEVKNIKLKLPDTVPPMVATFINMLVPLLTNIFIFYGINLIFLAATNKIFPE
                     AVMEVLTPATNIAGSLGGFLLIVTLGNILWLFGINGSSIIFPIVFTLGMAQTGLNAEQ
                     LANGETMTHLMNLQMFRISVLGGAGGTLGLVLLMMRSKVPEYRTIGKLSLVPGICSIN
                     EPVIFGLPIVFNPILAIPFLITPIISLLLTYFAQQLGWIGIGFIVDPSFTPFFAQAYL
                     SSMDWRNILFCLLLIVISIFIYYPFFKVMESNKTKLVDEKL"
BASE COUNT         1585 a          708 c          847 g         1388 t
ORIGIN      
        1 ttataaactc catttgcttt cgcaatttta atgccttgcg cctggcgtcg tttagattcg
       61 gtacgctctt gttcagcgat catggccaaa atttggatga tcagatcctt aatgaattta
      121 tccaggagag ggttgccaat tgcttcagcc atgatcggta gactggtgat gattagctgt
      181 acgtttttct tctttaggta attgactgaa gcgatgatct cgtcgtaatt tcttccaagt
      241 cgatcaatag cttccacaat aaaaatgtct tgatctcgga cgaaatccaa tgcttcttgg
      301 aaaacaggtc gatgagtaat cgttgcgccc gattgtttct cgatgaaaat tctcactgca
      361 ccgaattttt tcatttcttc aatctggcgt tgttcatttt gatcgatgga tgagacacgt
      421 atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaat acaccctaat
      481 catacacgat aaaaccagat ttttcaatgt tgtggtcgtg tctagttagg gtatacctta
      541 tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt taaatggcaa
      601 tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat taaaaatata
      661 ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta agaaaacgtt
      721 ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt atctttaggt
      781 attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc tgatagtaca
      841 aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga taggaacgga
      901 atagccattg gtaacccaac taacgactta actgttactg aaaattattt aatagtttct
      961 ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat gatttttgat
     1021 aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa aagaaatggt
     1081 tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa caattggatt
     1141 gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga atttgtgaac
     1201 acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc gaaagaagaa
     1261 tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa atcaatttct
     1321 aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata tcaaaaagaa
     1381 aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa ttgaaagtgt
     1441 tcataaaatc acccatttct ggacactttc tgtcattttt atatttaatt ggcacagttt
     1501 tttctaatta tttgtcatat tcatagtcaa ctatagctac aaaagcaact aattttggag
     1561 atagattgag atatttaaaa atctatcatg aaaaattagt tgcttttgtc acttagcgct
     1621 gaaaatttat gccatttatc tagaaaaatg acaacagagt tgggcaacag aatttaaaaa
     1681 tgatccggat ttcagaattt taaaggagtt ttattatggc gaaaattggg tatgctcgag
     1741 taagcagctt agattaaaat ttagaccgac aattagaatt attatcagag tgtgataaaa
     1801 tttttagtga taaagcaagt gggaaagata ccaatcgaga aggatttcaa gaaatgatga
     1861 aattcatacg tgaaggtgat attgtcgttg tgacagaatt aaaacgactt gaacgaaata
     1921 acaaagagct aacagaaacg atgaatttaa ttcagctgaa gaaagctaca ctggaagttt
     1981 tgaatttgcc agcgttaaca ggtatcactg atgataattt acgtcgatta cttaataact
     2041 taattatcga actatacaag taccaggccg aagaagaacg tcggtatatt cgcgaaacgc
     2101 aacaacaagg aattgcactc gctaaagcaa aagggaaata caagggaggt acgccaaaat
     2161 atcgtgagaa tgatccgcga cttcaattag catttaattt gtttttgact agatctacag
     2221 ataaagaagt tgaagagcta acagggatta atcgtagaac gtttagaaga tatcgaatga
     2281 aacatggtat tactaatgaa gttagggagc aaaaaaataa atctttcagt tgaggctaat
     2341 ataattttgc aagaaaggga tttttatgaa agaaattaga ttttcaaatc aaaatatgca
     2401 gaattactat aatgaaatta tgaatatgga aactagtgaa ttgaatttaa ttatagccga
     2461 aaaaaaagtt gcattggata ggaataaaaa cttattaaat gtagttatga tctgttatat
     2521 ttcatttcta atactaggtc ttccacaagc agtgtttcct gaaatgtttt ctggagactg
     2581 gggtattgtc agctattcta tattaacatt gattgctatg gttttaggta cttcatttta
     2641 taatgctttt gtaagtaagc atgttgagga atatgaagta ttaatgtact taaaagagaa
     2701 aaaaacaagt aattaatatg agaacaccac gcatagtttt tattttgaga tatcctagaa
     2761 tgaaacacat taagaacgaa agcaaagcaa aagacggcag aacttctact accttctaag
     2821 ttttttcata tttgtttgtt atgctataca tagatctgca taattagact tgcgctgccc
     2881 gttattgaag tttcaggcag cgctcttttt gggggatcga taatggaaga agaaaaaata
     2941 tttgagaaac gctggcagct agcatcaagt gaacaaagag caagatacaa taatttgatc
     3001 acctcctacc ccactgttga ctagacatat aaggaaaaga aatacttact ttggctgtgc
     3061 cagttagata tagatacctt tgaaacattt gaagtgatcc tagataaaat taaacagaat
     3121 tgatcagaaa caagcgaagc cttctctcgg ttcgcttgtt ttgctattta ttagttggct
     3181 cagggcaatt ctaagctcgt ttgaaagaaa accgaatgac gactatagtt tttcatctac
     3241 taattttgtt ttattgctct ccatgacttt aaaaaatgga tagtagatga agatgctgat
     3301 gacgatcaac agtaggcaaa agagaatatt gcgccagtcc atacttgaaa gataagcttg
     3361 tgcaaaaaaa ggtgtgaagg aaggatcgac gataaatcca atcccaatcc atcctagttg
     3421 ctgagcaaag taggtcagca ataatgaaat gatgggcgta atcaaaaatg gaattgccaa
     3481 aatagggtta aaaacgatag gtaatccgaa aatcactggt tcgttgatgg aacagattcc
     3541 aggaaccaat gacaattttc caattgtgcg atattcgggt actttgcttc gcatcatcaa
     3601 taaaaccaaa cccaaagtac caccggctcc accaagtaca gaaatacgga acatttgtaa
     3661 gttcattaag tgtgtcatgg tttcaccatt tgccagttgt tcagcattca aaccagtttg
     3721 agccattccc aatgtaaaga cgatagggaa aataattgac gagccattga taccaaatag
     3781 ccataggatg ttacccaaag tcacgatcaa taagaaacca cctagactgc cagcgatgtt
     3841 cgttgctgga gtcaggactt ccatcaccgc ttcagggaag attttgtttg ttgctgccaa
     3901 gaaaatcaga ttgatgccat aaaagatgaa tatatttgtc agcagtggaa cgagcatatt
     3961 gataaaggtt gctaccatgg gtggaactgt atctgggagt ttcaacttaa tattttttac
     4021 ttcaaatagt cggttgattt ccactactag caagccgatg ataattgcga cgaacaatcc
     4081 gtttgtccca aggaaattaa gattgatggc accttcttcc actggtgtac aaaccattag
     4141 ataaatgaca gatgcaacca tgccattcat ggaaggatta attttgtatt cattggcaag
     4201 ggaaaatgca atgccaaaaa cactaatgaa tccgatgatt cccattgtca aattataagg
     4261 ggctgtgatg agatcataat ttgctacggc aaaatctttc cagctggcca taaatttcat
     4321 gaaaatatta gctgtatctg gattgtattt atcaatattg atgggtggat ttgcaaaaat
     4381 cagaaaaaaa gaaccgataa caataaaggg taggccaaac atcataccgc tggatatagc
     4441 ttttaggtgg cgctgattac ctatcttggc tgcgatgggg ctaagtatgt cattcagttt
     4501 catgataaac gcagaatttt ccatataa
//
LOCUS       DAIGUC010000114         4461 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.119, whole genome shotgun sequence.
ACCESSION   DAIGUC010000114 DAIGUC010000000
VERSION     DAIGUC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.119"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            574..1008
                     /locus_tag="NOB46_002754"
     CDS             574..1008
                     /locus_tag="NOB46_002754"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059644.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="NOB46_002755"
     CDS             2298..3221
                     /locus_tag="NOB46_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1059645.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="NOB46_002756"
     CDS             3237..3776
                     /locus_tag="NOB46_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI1059646.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DAIGUC010000115         4430 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.120, whole genome shotgun sequence.
ACCESSION   DAIGUC010000115 DAIGUC010000000
VERSION     DAIGUC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.120"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(543..2048)
                     /locus_tag="NOB46_002757"
     CDS             complement(543..2048)
                     /locus_tag="NOB46_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI1059647.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="NOB46_002758"
     CDS             complement(2045..2731)
                     /locus_tag="NOB46_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI1059648.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQFKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB46_002759"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB46_002759"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCI1059649.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          918 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgaattggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DAIGUC010000116         4386 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.121, whole genome shotgun sequence.
ACCESSION   DAIGUC010000116 DAIGUC010000000
VERSION     DAIGUC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.121"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            2..74
                     /locus_tag="NOB46_002760"
     tRNA            2..74
                     /locus_tag="NOB46_002760"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="NOB46_002761"
     tRNA            78..150
                     /locus_tag="NOB46_002761"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="NOB46_002762"
     tRNA            155..225
                     /locus_tag="NOB46_002762"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="NOB46_002763"
     tRNA            238..311
                     /locus_tag="NOB46_002763"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="NOB46_002764"
     tRNA            323..394
                     /locus_tag="NOB46_002764"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="NOB46_002765"
     CDS             660..1853
                     /locus_tag="NOB46_002765"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCI1059650.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="NOB46_002766"
     CDS             1983..3455
                     /locus_tag="NOB46_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI1059651.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="NOB46_002767"
     CDS             3538..4326
                     /locus_tag="NOB46_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCI1059652.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
BASE COUNT         1282 a          732 c         1021 g         1351 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 atagga
//
LOCUS       DAIGUC010000117         4375 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.122, whole genome shotgun sequence.
ACCESSION   DAIGUC010000117 DAIGUC010000000
VERSION     DAIGUC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.122"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(83..1051)
                     /locus_tag="NOB46_002768"
     CDS             complement(83..1051)
                     /locus_tag="NOB46_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI1059653.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1500..2906)
                     /locus_tag="NOB46_002769"
     CDS             complement(1500..2906)
                     /locus_tag="NOB46_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI1059654.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPNLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQTAVKERESVSDELRYISRQREE
                     NEREKALVASERVKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            complement(3127..3489)
                     /locus_tag="NOB46_002770"
     CDS             complement(3127..3489)
                     /locus_tag="NOB46_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059655.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENATMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDGLFGVITNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3493..3831)
                     /locus_tag="NOB46_002771"
     CDS             complement(3493..3831)
                     /locus_tag="NOB46_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059656.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3810..4229)
                     /locus_tag="NOB46_002772"
     CDS             complement(3810..4229)
                     /locus_tag="NOB46_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059657.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4222..4362)
                     /locus_tag="NOB46_002773"
     CDS             complement(4222..4362)
                     /locus_tag="NOB46_002773"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059658.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1251 a          978 c          603 g         1543 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga gggggctgtt aatttttccc
     1021 actcatttat gatcgtgcct tttttactca aattttgttc ctcctcaaag aaaaagagac
     1081 ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc aaaaaatctc
     1141 tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg agctagtgcg
     1201 attagtttcc gtaaaggtcg agaacgtgtc cagcgttgct cgactttatt tttttgctct
     1261 tttttcagtt tatttatttg ataactcaat aatagcactt ctctttagct atgcaaatat
     1321 ccaaaaaata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta acgctaggtt
     1381 ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt agtggtttag
     1441 ccgtcaactc cttatcctcg gcacaaaccg cctccggtac cgttgactgc acatcgtaac
     1501 taccactcga tctcatcttc agaacgctct aatttacgct gtgagacgtt ttgacgataa
     1561 aataaggttt tctcctgctc taacacttct aattcctcag aaagccccat atccttttct
     1621 gcaagaccaa aacggataga caaacgagtg atcgattttt gaaatgcgtt ttttaatcgc
     1681 tctaaacgct ggcgtaaaga gcgattttct tctttcagct ttttattttc cacttgtaaa
     1741 tctgctaatt gttttctacc agacaaatga cgctcttctt ccaatgtagc tacatactca
     1801 tttaattctg tattttgctc aagcatctgt aaatattgct cactcatgtt atcagcattt
     1861 ctcttggcat ttgttgctct cgtagctcgt tgatacaaat caacaaaatc attcccagat
     1921 aaatgatacg aaccatcagg aagcctcttg aaactttcta aaggaacaat atctttttgg
     1981 aaaatgaccg ccatctcttt ttttacattc agcatatttt tcttctcttc ttcaatcttc
     2041 actctctcag aagccaccag agccttttct cgctcatttt cttctctttg cctagaaata
     2101 tacctcaact catcagaaac gctctcacgc tcttttacgg ccgtttgacg caattctgaa
     2161 atctcgctca tgatttcttt atattcgtga acatctttga ttttgttagt accgactaac
     2221 tcacgctccc aaccaaaatc tgccatcaaa cgttcaattg actcaacttc ctgattccta
     2281 aaattattcc aaatcactcg accattctct ttatctgctc gtaaaccctg ctgttgcaag
     2341 gctttgttaa aacttggttg cttttgaaca ccccgtttat acccttcagc aacaggaaca
     2401 atattcaaat gcaggtgcgg acttacttcg tcattatgaa taacagcatt gtagacggat
     2461 aaattaggat tccgttcttt aaattctttg aaatattcaa ctaaaatttt gttggcaatc
     2521 actcgatttt gttctgcttg ttgttccgat atgccagtag aagaaccatc atcacgagta
     2581 gtacgaaaat catcaagagt accaatttgc acgataaatt ctcgctgtgg ttccaatttt
     2641 ttatccttgc gaacctttgc taaatagtcc tcgatttttc tatcggctct tttctgcttt
     2701 gcattatatt tttctacggc ttcaccgaat aattcttcat atttttcacg aatatttgtt
     2761 tgttctaaat agatattttc atccgatttt gtgaaatcaa tatgcttatg ccagtcattg
     2821 attttttggc tatcagttaa ctcacgatta ttatgagaaa tgcttgtatt ctttgttccc
     2881 tttttgaacg aaatactgaa ccccaagtta aaaccctcct tcggctgtcg ctaataaaaa
     2941 gagtgtaaac ctttctgtta ctctttgtca aagagtaaca ttttcctaat tgtgacatgg
     3001 ctgtcacaat tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag
     3061 gagccgaaag cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat
     3121 aatcgcttat cgtaaattca cgtcattaaa tattgacgta aatttactct cactcatctg
     3181 acttttctta ttcgttatca ctccgaataa gccgtcagat tcatcgggat aatctcgttc
     3241 gcttggcgct gatttttcat cagcaagcca ctcattatcc actgtttttt cgtgttgctg
     3301 atcgtcagaa attgacgata accaccgctc aaaatcagca aaagattcaa acccaaaacg
     3361 cttgcgaaga gccttgccca ttgtagcatt ttctttctca atcaagcgtt ttttctgttg
     3421 acgaagtttc gcttgttctt tttttaattt ttcttcttgc gctttaatat ctgctaaagt
     3481 cattcccata aactacatct ccttttcttt ggaattaata acggaaattt ggtttaactg
     3541 cataacatga ctcattaatt tcaaccaaaa ttctttttct gattcatcag ttgtttgcgc
     3601 taaatgctta tgaacaaatt cattagtcaa aactgaagat tttgctaaat cagcattgat
     3661 aaccgagttg agaacatcca taattcgttc aagcatttca ctataattat cttcatccgg
     3721 caaattcaaa taatcagcta accgttcata catcaattca attctatcga ctgtttcttc
     3781 tctcaaatca attttatcca tgtcacacct cacttccaga attgccacca ttttcgattt
     3841 tttaattctt gattttctag taacaactga tcgttttttt gttgctgaag caaagtcaat
     3901 ttttgttggt cacgaatcat ttccgttaat tcagaaatat gcctatcttt ttccgctaat
     3961 tgttcacgca aaaattcatt ttctttttct aacgggaaat cattgcctgc atcattgacc
     4021 ggtaaatcac cagtcaattg accacctttt gaccgataaa ttgaccgcac aacaccaatc
     4081 aattccttgt ctaacatgat aaccccatta tctttatacc gagcaaggtc ataacctgca
     4141 ttgaccagtt gattgcgcac tgtattttta gatataccca actcatcagc aaggtttttt
     4201 atggtcattt tttctggcaa atcagtcatt atcttctccg ttactttcag ctaccccata
     4261 aacatattta acagcatgct tagggataat gattggggaa tcaattttat tatttttcaa
     4321 aatcaactca tactgcgtta catcaagtaa cttaccggac atttttttgc tatcc
//
LOCUS       DAIGUC010000118         4335 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.123, whole genome shotgun sequence.
ACCESSION   DAIGUC010000118 DAIGUC010000000
VERSION     DAIGUC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.123"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..665)
                     /locus_tag="NOB46_002774"
     CDS             complement(<1..665)
                     /locus_tag="NOB46_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HCI1059659.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENE"
     gene            780..2492
                     /locus_tag="NOB46_002775"
     CDS             780..2492
                     /locus_tag="NOB46_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059660.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            2495..4267
                     /locus_tag="NOB46_002776"
     CDS             2495..4267
                     /locus_tag="NOB46_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059661.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         1339 a          753 c          922 g         1321 t
ORIGIN      
        1 tgctcgtttt ctcttctttt attttgttgg cataagcctt caatataggt ttgtgcactc
       61 gttagaaaga gtgctttttc attcaattct gcatgggact gcatactttc tttaaatccc
      121 tctaattgat tttcaactac ataattacgc ataaatagaa ctgtttcttt caaaaattca
      181 tttccgtcca taattttttg tcgaagctgc tgttcatgct gctgatccat taactgtcca
      241 atcaataaat tgtggagaga ggcaatggcc tgatgacttt gggtgactga aaatccttca
      301 cgaacaagta attggatcat ttgctccaaa tgttctaatc gactcggaaa agcgggcaca
      361 gtattgattt ctaattctgc cccacaaggg aaacgtgtat aaaggtcata gtaattttcc
      421 atatactgca gcaactgttc attccaaggc aaagttggat ctggaagcgc taattcttct
      481 tccattgttt cagccatttt ttgcaagagc tgttgtttgt ttttgaaata ccaatataaa
      541 gcaggtgctt gaacatgaat tctgtttgcg atgtttcgca tggaaagctg cgaaagagct
      601 tgtgtttcag ccaggatatc aaaggcggcc tgaatgatga ttgcttgaga aagctttatt
      661 tccattttat caacctcgtg tattgcatta tctttttaaa catggtaaat tgttagtcgg
      721 tctaatttta cagtgttaaa ttagtcctgt caatttaaac aaaggggtgt aatcaacgaa
      781 tgaaattaat cttacgacat gcgaaaaaat ataaagtagc tgtttttatt tccttgctgt
      841 ccgtagcagt catggttgca gcagcattat ggcaacctaa gttactacag caagtattgg
      901 aagctattat tacagaagat aatgatgaaa tgaaaacaat tggtatttac ctgatcagtc
      961 tggctttgct aggattagcc gcaggtgtaa cgaacacgat tttctctgca aaagtagctc
     1021 aaggcgtaag tgcagatatc cgagaagaag catttcgaaa gatccagaca ttttcatttg
     1081 gaaatatcga acagttctct gctggaaatc ttgttgttcg tctaacaaat gatatcacgc
     1141 aaatccaaaa tttagtgatg atttctttgc aatcactttt tcgaattcca ttcttattta
     1201 ttggtgcctt cattttagct atgatcacga tgccgcaatt atggtggatc atcgtagcgc
     1261 ttatcgttac ggtatttctg attacggcac tttcatttac aaggatgggc aagcacttca
     1321 tgatcattca aaaactgatt gatcgtgtga atagcattgc aaaagaaaac ttactaggga
     1381 ttcgtgtagt gaaatctttt gtacaagaag aaaaccaatt gaagtcattc agcaaagtaa
     1441 gtgaggactt aacaaaacac aacatcatag tcggtacatt attttctgtg atgatcccgt
     1501 ccttcatgct ggctgccaat ttggctgtgg ttggggcgat cttttttgtg agcgatcttg
     1561 ttaaagatga tcctacgtta attggtggaa ttgcttcatt catgaactac ttgatgcaga
     1621 ttatgatggc aatcattatt ggcggaatga tgatgatgat gacttcaaga gcagccgtat
     1681 cgctgaagcg gattgcggaa attttagatg ctgaaccaga tcttacttat ttagacgttc
     1741 cagaacaaga gttgacgggt tctgtcactt ttgaccatgt ttcttttcgt tatcctggtg
     1801 aggatacaga tacgcttaaa gatatcagct tttctatcaa acctggagaa atggttggta
     1861 tcgtcggggc gactggtgcc gggaagtcaa cactagcaca attgatccct cgtctatttg
     1921 atccgacaga aggcaaagtt gaagtaggtg gtgtagatct tcgtcaagta aatgaaaaga
     1981 gtttaagaca aacggtttcc tttgttttgc aaaaagcaat tttattctca ggaacgattg
     2041 ctcaaaactt gcgccaaggg aaaaagaatg caacagaaaa agagatggaa catgcttctt
     2101 ctattgctca agcaaaagaa ttcatcgaaa agttatctga tcgttacgaa gcaccaatag
     2161 aagaacgtag cagtaacttt tctggtggtc aaaagcaacg tttatccatt actcgtggcg
     2221 ttatcggtaa tccaaagatc ttgatcctag atgacagtac gagtgcactg gatgctcgct
     2281 ctgaaaagct ggtccgagaa gcactcgatc gagatttgaa gggaacaacg acgattgtca
     2341 tcgcacaaaa aattgcttct gttgtcaaag cagaccgcat cttagtattg gatgaaggca
     2401 gattagtcgg cgaaggaacc catgaggaat tggtagctgg aaaccgtgtc tatcaggaaa
     2461 tctttgaaac tcaaaaagga acggaggagt aagtatgact gatctaataa aagcaagtaa
     2521 atttttctat cactatttga agcggtacaa actctccttt ttctttatct ttatcacagt
     2581 gatcattgct acctatctac aagtaaaggc acctcaatac atcggggaag cttttcaaga
     2641 attagctaat tacgtaggag gcttgatgca aggcgtagac gataaaagca aatttgtttc
     2701 tgtaatatgg aaactcttgc tgttttatgt actagctagt gcagccaact ttatctatag
     2761 tattttgttc acacaagtag tagggaagtc aacgaaccga atgcgtatcg gtctattcaa
     2821 caaattggaa aaattgacga tccgtttctt tgattctcat caagacggtg aaattttaag
     2881 tcgttttacc agtgacttag ataatattca aaatagtttg aaccaagctt tgcttcaagt
     2941 catcacgaat gctgttttac ttgtcgggat cttgatcatg atgttccgcc aaaatgtaga
     3001 gttagcttgg gctacaattg cttccactcc agtagccgtt ttgatagctg tcttgattat
     3061 ccgcaaagca cggaaatatg tggatcttca gcaagatgaa gtggggaaac taaatggtta
     3121 tatggatgaa aaaatcagcg gacaacgtgt catcatcaca aatggcttac aagaagaaac
     3181 gattgaagga ttcttagagc ataatcaaag tgttcgcgaa gcaaccttca aaggacaagc
     3241 ttattctggt ctactatttc cgatgatgca aggaatgtca ctggtcaata cagcgatagt
     3301 tatctttttc ggcggctggt tagcattaaa tggtgatttg gaacgttcgg tggcattagg
     3361 cttagttgtg acattcgtcc agtattcaca acaatattac caaccactga tgcagatttc
     3421 atctggatac agcatgatcc aattagcgat tacaggggca agacgattga atgaaatatt
     3481 tgatgaaaaa gatgaagtca aaccagaaaa cggtaaagca tttgatggtg ttgaaaaagg
     3541 tcttgcgttg cagcacgtag attttggtta ttctccagaa aaactagtct tgaaagatgt
     3601 ctcgatcaat gtggacaaag gagaaatggt tgctcttgtt ggtccaacag gatcggggaa
     3661 aacgacgatc atgaatctgc taaaccgttt ttacgatgtc aatgatggtt cagtagtcat
     3721 cgatggaata gatatccgag attatgatct tgatgcatta cgtagacatg taggaatcgt
     3781 tttgcaagaa tctgtattgt tctccggaac gatcaaagac aatatcacat tcggcaaacc
     3841 ggacgcttca gatgaagaag tcatcaatgc agcaaaacaa gcgaatattc atgacttcat
     3901 catgacgtta gaaaaaggtt atgatacaga gatatccgaa gaaaataact tattcagtac
     3961 aggtcaaaag cagttgatca gtattgctcg aacgatcatc acaaatccat ctttattgat
     4021 tttggatgaa gcaacaagta atgtagacac ggtaacagaa gcaaggatcc aaaaagcaat
     4081 ggatgaagca atcaaaggaa gaaccagctt tgtgattgct caccggctga aaacaatctt
     4141 gaatgcagat agaatcgttg tcttgcgtga tggggaagtc attgaagaag gcagtcatca
     4201 tgagttatta gcagaaaatg gattttatgc ggaactttat cataatcaat ttgtatttga
     4261 aagttaaatt aaaagaacct cgttataacg gggttctttt tatatatttt atgttgtttg
     4321 tttttataag gggca
//
LOCUS       DAIGUC010000119         4299 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.124, whole genome shotgun sequence.
ACCESSION   DAIGUC010000119 DAIGUC010000000
VERSION     DAIGUC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.124"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..430)
                     /locus_tag="NOB46_002777"
     CDS             complement(<1..430)
                     /locus_tag="NOB46_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI1059662.1"
                     /translation="MTYVFLPKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISV
                     FGDVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILAVATVGLYGIGDCI
                     FTGLFSINTNESSWNLSTWIHNTGSGLGYAGFLLFPLLLVL"
     gene            complement(488..1540)
                     /locus_tag="NOB46_002778"
     CDS             complement(488..1540)
                     /locus_tag="NOB46_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI1059663.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(1553..2491)
                     /locus_tag="NOB46_002779"
     CDS             complement(1553..2491)
                     /locus_tag="NOB46_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI1059664.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(2941..3591)
                     /locus_tag="NOB46_002780"
     CDS             complement(2941..3591)
                     /locus_tag="NOB46_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059665.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(3691..4200)
                     /locus_tag="NOB46_002781"
     CDS             complement(3691..4200)
                     /locus_tag="NOB46_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HCI1059666.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
BASE COUNT         1388 a          907 c          619 g         1385 t
ORIGIN      
        1 gcagaacaag taacaatggg aaaagtagaa agcctgcata gcctagccca gaacctgtat
       61 tatggatcca agtcgataga ttccaagagc tttcattcgt attgatactg aataacccag
      121 taaaaataca atcacctatc ccatataaac caactgttgc aacagcaagt attgcaagtg
      181 tttttgatgt tccaacaaat aggtgataca acgcaggcaa cgaaagaaca aaaaaaagtc
      241 cagatacaac tgaccagacc aagaaagcac gtctgactgg actatctacg tcaccaaaca
      301 cactaattac ggtagtcatt tgattcagtt tgggataaaa aaggccaagg atatacggtg
      361 tcgataaatc actaatcaca cctaataata aaaaataaaa accatatttt ggcaaaaaaa
      421 cgtaagtcag atgttgttga catctcactt acgcatccat tgattgaaaa tttcttagta
      481 aaatctacta gcctaaaaat ttgaagactt cttctcgatc atacagttta aatactttct
      541 cgcataaaaa ttgagtaatt agtgccgcaa aaacagggat gactaaccaa caaagaacaa
      601 caagaaagcc atttagccct gcatctaaag aagccaacgg accaacaagt ccgaccacac
      661 cgaaaccagc agaagcaggc gtacctgaaa tagaaaatag agcgacagga atagctgtaa
      721 tcactgcact aactaaacaa ggaataagaa tcacaggttt tctaaataga ttaggcatca
      781 tcatcttcat agcgcctaaa gcaatcgcaa ttgtcacacc tgacttatta accttccaag
      841 agttcactac taaaacaaaa gtggttgcag ctacgcccat cgcagccgca ccagcagaaa
      901 caccatctag ttggattgcc attccgattg ctactgttga aataggagag ataatcaaaa
      961 aggcaaagga acaaccaatc aagatagaca ttaacagcgg ttgtaaggta gtgaagttat
     1021 taatcaatga tccaattgca gaagtaattg ctgttacaaa agggaataaa taaaaaccaa
     1081 gtaaacctgc acctacacct acaacaatcg gtgttaacac aatcgacact gacccaaaac
     1141 tatttccaat cagtaaaatc agcccgacag caatcgatgc tgtcagcatc gtattaataa
     1201 tatcgcctgt accagcacca acgtaaacac ccgtttcacc caaatcaggt gtgaatttga
     1261 ctacaccaga accaacaaaa gaagctccgg ctacaaccat cattctcatc ggatcaaatc
     1321 caaattgtaa ggcaatcaaa ccaccaatga tcaaaggtgt tgctaattga aaaataactg
     1381 ctaactgtgc gatcgttacc gcaaagggat acgcactaaa atattttaaa atagcaccta
     1441 atactgcatt aggaatcaat ccaataatga ttcctgttgc tgtaccagcg aggactttat
     1501 tcagaaaaat tttcggtgat attttttgtg aagtttccat tcaatctctc ctttatttta
     1561 cgttcaaact atcttctttt gcatggacaa gctcagtcaa gaaatcacaa taaggcgtcg
     1621 caacaccata tttcttccct tttctagaaa ttgcgccatt gatataatcg atttctgtta
     1681 atcgatggtt cttaatcaag tcttgataca ttgaaggata atgtaaccca attgtttccg
     1741 ggtcaaaaca agattcacaa tgtgcaatga cttctgggac atctagttca atcttctcta
     1801 ctgctgctac tttggcaaac tcattgacaa tcgtcgccac cattttatga gcagtcgatg
     1861 tttttcctag ctcagccata ttaacgtcta agattgtgca tagtccgttc attgttccgt
     1921 tcacacatgc tttgcgataa atagaatagt gaatattgtc agaaaaatga gcatttaatc
     1981 ctgattcaga caatttgtct gctaattttt ttgcagctgc ttcttttcca tcacctaaat
     2041 tttgtaattc tactgaacca cttccaaata atttgacctg accaggacct tcaagacctg
     2101 ccgtccacat ggtatttcca atatagatat tttccattgg tacaaatttc tcaataatat
     2161 cttcatgccc gataccattt aatagacata agacctctgt atcttttttg attaatgatt
     2221 ggatatcctg cagcattttt tccagctgca tcgctttggt aaatagaata atcagatcaa
     2281 cttgatcttc tttttctact tcggattgaa gaacgattgg tagttttgct tctacctctt
     2341 taccattaaa atttgcttgt aatccatgtt ctttgatttg ttggacatgt tctgcccagc
     2401 catcgattaa taatacttcg ttcccacttt ggtgaagcat taacccaaag cgacttccca
     2461 ttgcgccagc gcctgcaatt gctattttca ttgattcttc ctcctttttc tttctattat
     2521 acttatttga gaatcatttc acaaccttgt tttgttattc ttctcttatt tatcatgttt
     2581 atatccacca ttcaagttat tttatcagca aatcaataaa actggaatag aatcccaatt
     2641 tcatcgtaag agaaactaga ctagcaataa gaaaatagaa acattcatag aaaaaacctc
     2701 actcctctga ttataaaaga gggggcatta acctcgtgta tactaaaacc ttccattcat
     2761 tcgatggatg attttctttt tgtgaaaaaa tattcattgt agtacgatgt tgcgcaacac
     2821 agacggatgg tattgcttat tatttattaa aatcgaacaa tacacttatt caaaaacttc
     2881 tttcccagat tttcttccat ttttacagtt ataactagta ttatcatgaa aaatagcctt
     2941 ttattgtcta tgggaataat aatttaaaat tggtactttt ttattaatta gttcatcgcc
     3001 caataatctc tccagtttct tagcatctcc tgactcaacc ggaattatcc aagcccagtc
     3061 caaataattt tttaaaatct catcatattt tgcaaatatt tcattgccat attccgtcct
     3121 taaaattata ttttcagtgc cagacaagtg atttgtattg agttgataaa aaagatctcc
     3181 atctaaaaaa atatcattag aagaagattt ccccacagta atgaccattc catcagctct
     3241 atgtgttaca tacaaataat tgtatgacct catttcacct aatgaatcaa ttatttcttg
     3301 ccctttagct ctaatatatt gatctctatt acctatctca ctcttattta acaaaagttt
     3361 tttcatgtca aatttaatcg gctgttttat ttttgtaaat tcgcttctac tactaatcca
     3421 atccgagatt aatttttcaa catgtcccag agtaaactct gatttattcg ctaaatactt
     3481 tttttgttgt attaaagaca tctttccccg aagctcaaaa ttgagcctac atcgattctc
     3541 tatctcttca aaaagcatct tatcttcatc attcttatat tcatcattca taaaaccaat
     3601 ccagctcctc gattaagata atattttaat ctcatacaaa aactagctct catcaaaaca
     3661 accattgttt tgatttctca tgaaatttct ttatactttt ctccgattat aaattcctaa
     3721 ccccttgaga aaattacgca tatatttatc tccgcaaggc ttaaaatttc gttggccttc
     3781 ttttctcaaa aatgccccga tttcgccttt tgatggatag atttctgcct cagcaaaaac
     3841 gtctaaaata tcatcagtgg tcatagacaa ggcgattttt aattttttta gcaacacatt
     3901 gttgatatat ttgatttcct tgcttttttg cggcgtgtct actatcggct tatctttttg
     3961 cggaccacgt gccaagagaa tcaggccatt taggaatgcg tcaaaaactt ggttgttgat
     4021 ggttttttca tacacattat tttctgcatt atctttgttc ttatcctgta ctttggtcag
     4081 taccgcctga gcttcttctt tagtcagtgg tacaccgcct agctcaaaag ctttaatcaa
     4141 atccgtatct ttcaaatcaa tcgcataacg caatcgcaat aacctatcat tgttattcat
     4201 ttgttcctcc gaagtattta gtctttactt tcttacgtac tttttgtctt gctaagattt
     4261 ttaggatcaa tgataaaaac cgcatcactt atgataagg
//
LOCUS       DAIGUC010000120         4157 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.126, whole genome shotgun sequence.
ACCESSION   DAIGUC010000120 DAIGUC010000000
VERSION     DAIGUC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.126"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            179..775
                     /locus_tag="NOB46_002782"
     CDS             179..775
                     /locus_tag="NOB46_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI1059667.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="NOB46_002783"
     CDS             899..2698
                     /locus_tag="NOB46_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI1059668.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESMKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="NOB46_002784"
     CDS             complement(2976..3188)
                     /locus_tag="NOB46_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059669.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="NOB46_002785"
     CDS             3650..3799
                     /locus_tag="NOB46_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059670.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="NOB46_002786"
     CDS             complement(4052..>4157)
                     /locus_tag="NOB46_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1059671.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1229 a          707 c          728 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagta tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAIGUC010000121         4145 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.127, whole genome shotgun sequence.
ACCESSION   DAIGUC010000121 DAIGUC010000000
VERSION     DAIGUC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.127"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..765
                     /locus_tag="NOB46_002787"
     CDS             <1..765
                     /locus_tag="NOB46_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059672.1"
                     /translation="IILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAE
                     YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQ
                     GLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIY
                     APQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVC
                     LTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            875..925
                     /locus_tag="NOB46_002788"
                     /pseudo
     CDS             875..925
                     /locus_tag="NOB46_002788"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            959..2335
                     /gene="tet(L)"
                     /locus_tag="NOB46_002789"
     CDS             959..2335
                     /gene="tet(L)"
                     /locus_tag="NOB46_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCI1059673.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2930..3241
                     /locus_tag="NOB46_002790"
                     /pseudo
     CDS             2930..3241
                     /locus_tag="NOB46_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            3376..4023
                     /locus_tag="NOB46_002791"
     CDS             3376..4023
                     /locus_tag="NOB46_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HCI1059674.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         1364 a          562 c          778 g         1441 t
ORIGIN      
        1 attatacttt ctttcttagg gaaagtacaa atggaagtga ttagtgcact gttgcaagaa
       61 aagtatcatg tggagataga actaaaagag cctacagtca tttatatgga gagaccgtta
      121 aaaaatgcag aatataccat tcacatcgaa gtgccgccaa atcctttctg ggcttccatt
      181 ggtttatctg tatcaccgct tccgttggga agtggaatgc agtatgagag ctcggtttct
      241 cttggatact taaatcaatc atttcaaaat gcagttatgg aagggatacg ctatggttgc
      301 gaacaaggat tatatggttg gaatgtgacg gattgtaaaa tctgttttaa gtatggctta
      361 tactatagcc ctgttagtac cccagcagat tttcggatgc ttgctcctat tgtattggaa
      421 caagtcttaa aaaaagctgg aacagaattg ttagagccat atcttagttt taaaatttat
      481 gcgccacagg aatatctttc acgagcatac aacgatgctc ctaaatattg tgcgaacatc
      541 gtagacactc aattgaaaaa taatgaggtc attcttagtg gagaaatccc tgctcggtgt
      601 attcaagaat atcgtagtga tttaactttc tttacaaatg gacgtagtgt ttgtttaaca
      661 gagttaaaag ggtaccatgt tactaccggt gaacctgttt gccagccccg tcgtccaaat
      721 agtcggatag ataaagtacg atatatgttc aataaaataa cttagtgtat tttatgttgt
      781 tatataaata tggtttcttg ttaaataaga tgaaatattt tttaataaag atttgaatta
      841 aagtgtaaag gaggaattaa ttatgaagtg aaatgaatgt aacagggttc aattaaaaga
      901 gggaagcgta tcattaaccc tataaactac gtctgccctc attattggag ggtgaaatgt
      961 gaatacatcc tattcacaat cgaatttacg acacaaccaa attttaattt ggctttgcat
     1021 tttatctttt tttagcgtat taaatgaaat ggttttgaac gtctcattac ctgatattgc
     1081 aaatgatttt aataaaccac ctgcgagtac aaactgggtg aacacagcct ttatgttaac
     1141 cttttccatt ggaacagctg tatatggaaa gctatctgat caattaggca tcaaaaggtt
     1201 actcctattt ggaattataa taaattgttt cgggtcggta attgggtttg ttggccattc
     1261 tttcttttcc ttacttatta tggctcgttt tattcaaggg gctggtgcag ctgcatttcc
     1321 agcactcgta atggttgtag ttgcgcgcta tattccaaag gaaaataggg gtaaagcatt
     1381 tggtcttatt ggatcgatag tagccatggg agaaggagtc ggtccagcga ttggtggaat
     1441 gatagcccat tatattcatt ggtcctatct tctactcatt cctatgataa caattatcac
     1501 tgttccgttt cttatgaaat tattaaagaa agaagtaagg ataaaaggtc attttgatat
     1561 caaaggaatt atactaatgt ctgtaggcat tgtatttttt atgttgttta caacatcata
     1621 tagcatttct tttcttatcg ttagcgtgct gtcattcctg atatttgtaa aacatatcag
     1681 gaaagtaaca gatccttttg ttgatcccgg attagggaaa aatatacctt ttatgattgg
     1741 agttctttgt gggggaatta tatttggaac agtagcaggg tttgtctcta tggttcctta
     1801 tatgatgaaa gatgttcacc agctaagtac tgccgaaatc ggaagtgtaa ttattttccc
     1861 tggaacaatg agtgtcatta ttttcggcta cattggtggg atacttgttg atagaagagg
     1921 tcctttatac gtgttaaaca tcggagttac atttctttct gttagctttt taactgcttc
     1981 ctttctttta gaaacaacat catggttcat gacaattata atcgtatttg ttttaggtgg
     2041 gctttcgttc accaaaacag ttatatcaac aattgtttca agtagcttga aacagcagga
     2101 agctggtgct ggaatgagtt tgcttaactt taccagcttt ttatcagagg gaacaggtat
     2161 tgcaattgta ggtggtttat tatccatacc cttacttgat caaaggttgt tacctatgga
     2221 agttgatcag tcaacttatc tgtatagtaa tttgttatta cttttttcag gaatcattgt
     2281 cattagttgg ctggttacct tgaatgtata taaacattct caaagggatt tctaaatcgt
     2341 taagggatca actttgggag agagttcaaa attgatcctt tttttataac aggaattcaa
     2401 atctttttgt tccattaaag ggcgcgattg ctgaataaaa gatacgagag acctctcttg
     2461 tatctttttt attttgagtg gttttgtccg ttacactaga aaaccgaaag acaataaaaa
     2521 ttttattctt gctgagtctg gctttcggta agctagacaa aacggacaaa ataaaaattg
     2581 gcaagggttt aaaggtggag attttttgag tgatcttctc aaaaaatact acctgtccct
     2641 tgctgatttt taaacgagca cgagagcaaa accccccttt gctgaggtgg cagagggcag
     2701 gtttttttgt ttcttttttc tcgtaaaaaa aagaaaggtc ttaaaggttt tatggttttg
     2761 gtcggcactg ccgacagcct cgcagagccc acctttacga agtaaagtat agtgtgttat
     2821 actttacatg gaagttgtac cgaaatattg tgttgtgaag tctatataat tttaaaatta
     2881 tgaagtctat atacgtgcgt aaagatattt aaagagatta aaaataataa aaataaaaat
     2941 tgaattaaaa agagatatgg ttgattattg gaacgattgt tttaatgatt tacatatatt
     3001 acaaccagat tggaaaacta tcgaacgtac ttctgataga gcaatggttt ttatgttgtt
     3061 gaatgatgaa gaagaatggg gaaaattaga aagacgtact aagaataaat ataaaaaatt
     3121 aattaaagaa atatctctaa ttgatttaac tgatttaatg aaatcgactt taaaagcgaa
     3181 cgaaaaacaa ttgcaaaagc agattgattt ttggcaacgt gaatttagat tttggaagta
     3241 aagtaacttt gttttataca aaatgttact ttagtataat taacgtttaa gaggtgacac
     3301 aatatatgaa aaaatcagag gattattcct cctaaataca aagagataag atgaaattta
     3361 ggaggaaaat tatatatgac ttttaatatt attaatttgg aaacttggga tagaaaagaa
     3421 tattttaatc attatttcaa tcaacaaaca acttacagtg ttactaaaga atttgatatc
     3481 actttactta aaagtatgat aaaaaataaa ggatatgaac tgtatcctgc tttgatttat
     3541 acaattgtaa atattataaa tcaaaataaa gtatttagaa caggaattaa tagtgaggga
     3601 aatttgggtt attgggaaaa attaaaccct ttatatacag tctttaataa agaaactgaa
     3661 aaattttcta acatttggac agaatcaaat gttagtttta attcttttta taatagttat
     3721 aagagtgact tacttgaata taaagataaa aatgaaatgt ttcctaaaaa accaatacct
     3781 gaaaacacag ttcctatttc gatgattcct tggattgatt ttagttcatt taatttaaat
     3841 attggtaata atagtagatt cctattgcca attattacaa taggtaaatt ttatagtaag
     3901 aataataaga tctatttacc agtctcattg caagttcatc atgcggtatg tgatggttac
     3961 catgtttcat tatttatgag tgaatttcaa aatatagttg atagtgtaaa tgaatggatt
     4021 taaatctaaa ataactttca taaacttaag taattatgat atttataagt ttatagcaac
     4081 taccattttt ggttgctggt gttttgattt tgaatttggt tttgaactta tggactgatt
     4141 tattc
//
LOCUS       DAIGUC010000122         4034 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.128, whole genome shotgun sequence.
ACCESSION   DAIGUC010000122 DAIGUC010000000
VERSION     DAIGUC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.128"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            73..234
                     /locus_tag="NOB46_002792"
     CDS             73..234
                     /locus_tag="NOB46_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCI1059675.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="NOB46_002793"
     CDS             253..1530
                     /locus_tag="NOB46_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1059676.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="NOB46_002794"
     CDS             1540..2196
                     /locus_tag="NOB46_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059677.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="NOB46_002795"
     CDS             2196..3572
                     /locus_tag="NOB46_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1059678.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..>4034
                     /locus_tag="NOB46_002796"
     CDS             3702..>4034
                     /locus_tag="NOB46_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1059679.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1612 a          440 c          704 g         1278 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catc
//
LOCUS       DAIGUC010000123         3970 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.129, whole genome shotgun sequence.
ACCESSION   DAIGUC010000123 DAIGUC010000000
VERSION     DAIGUC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.129"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..356
                     /locus_tag="NOB46_002797"
     CDS             <1..356
                     /locus_tag="NOB46_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI1059680.1"
                     /translation="EIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKS
                     LEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGN
                     VFKIEYTKKRQRLAY"
     gene            591..827
                     /locus_tag="NOB46_002798"
     CDS             591..827
                     /locus_tag="NOB46_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059681.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            834..2786
                     /locus_tag="NOB46_002799"
     CDS             834..2786
                     /locus_tag="NOB46_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI1059682.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2858..3355)
                     /gene="dfrG"
                     /locus_tag="NOB46_002800"
     CDS             complement(2858..3355)
                     /gene="dfrG"
                     /locus_tag="NOB46_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI1059683.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3585..>3970
                     /locus_tag="NOB46_002801"
     CDS             3585..>3970
                     /locus_tag="NOB46_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI1059684.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVE
                     PSKPEQREMLLDALLEISDSDPLLRY"
BASE COUNT         1415 a          640 c          697 g         1218 t
ORIGIN      
        1 ccgaaattgt aatcaaacag aaggtagaac tgtatcctaa tatgtgtgtg acgaacttta
       61 ccgaatctga acaatgggat acggtaatag agggaaacga tgacctttta gagaaatata
      121 tgtccggtaa atcattagaa gcattggaac tcgaacaaga ggaaagcata agatttcaga
      181 attgttctct gttccctctt tatcatggaa gtgcaaaaag taatataggg attgataacc
      241 ttatagaagt tattactaat aaattttatt catcaacaca tcgaggtccg tctgaacttt
      301 gcggaaatgt tttcaaaatt gaatatacaa aaaaaagaca acgtcttgca tattaagtag
      361 ttcagttttg gagtacaaaa agtgaaaatg taaacctaaa tgagtatcaa attgcaactg
      421 aatttgatac tcgtttttta ttgttaaatc aacgtttgtt gttaatttac accacaaaat
      481 gtaagttaaa atgtatataa aaatgcgaac gtgaaataat tattgtagga atgcaaattg
      541 gtgtgttaaa atggttacaa tttactaagc aaaaaggggt gcattttcct atgcaatttc
      601 ttgagccaaa aaataagaac gctaagtctg tggattggga aatatcagag caagtaaggg
      661 tgatagttaa gcaatacgct gaatatgcag agcgtactga aagcgaagca gtggatgaat
      721 tcttattgaa cattttagac gataagaagt ttattgaatg gattgccaac aagcgaagta
      781 ataagcggat tgttgaaaaa atgggtatca aagatagagt gggttgatag acaatgacca
      841 agcttaaaag attagccacg aaggaagatg aaattgtaga tgttaaaatt ccgatttcaa
      901 acgaagaatt aaaagatagg gctaaacaat atgatttatt aactccaaaa cgatttgcaa
      961 caaggtataa caaaatgttg ttcttgccaa cgtcttttaa atggaacggt tctgaatatc
     1021 ccattcaata taattactgc atcaatccgt tttgttgtaa ttttgggaaa gaacagcaca
     1081 aattcaaaga tgtaaaaggg aaaccaagtc gatataaaat gactggtagt tccaaagata
     1141 aaggtcataa aggtatgtac tgcaatgaca atcctattgg cagaggtgta tcgcaaaact
     1201 gtacagtaac ccctttatct aattggtctg ttgttgaaga aattaaacgc cttatagaaa
     1261 tcaatagcat ccaagatgtt gagccagatt atcaatttca taaagaaggc tgctcggaag
     1321 aagaatcaac cccattcaat gagccgaagc aattttacaa aagggggaaa agtaggggca
     1381 aatctcaacg ctatcaatgt aaggcgtgta agaagttcac taatgttcta ccaaaaagag
     1441 aagaaaccac tacttatcac caacaaaaga acaccattct tccaatgttc gctaagatgg
     1501 ttgttggaag ggtttcagtc agtcgtactt gtgatatttt aggaattgga gttggaacct
     1561 actatcataa gctggagtgg ctgtataggc gttgtttgga gtttttagaa cgatatgaga
     1621 cacaacccct tcaaacaaag aaatttaacg agatgtggct taatacggac aagatgcact
     1681 actacctaaa taacgtccgt aagaaaggac aaggttcaaa gaaatatacg gggtttgaag
     1741 accttaatat gcaaacgtat atagttgtat ctgctgaggt cttatcaaga tatgtgttcc
     1801 gttctgatgt tgcctatgat tggaatattt caatggatga attaaatgaa gatacaagaa
     1861 aattcaaaga agaccatctc aatactttta gtcgtaaaaa tgataggtta gattggtctt
     1921 attatccaca agaaccatcc gctaacgata gcgaaaatag gaatgcttat cttcacgaat
     1981 tagggaaaat tactaatagg agtagatttg tcgatggttt aaatgttgat gctccttata
     2041 ctacaactgc tcactattgg ttaattaaac aaatggttaa tgccgacgaa tggcgaatga
     2101 ttagtgatga tgacttctct attagaaacg ccttttatag agtattcacg aaagaattaa
     2161 ggttgagcga tgcacatcat tttatttgcc aagttaacaa gacgaaaagc agaaaacaat
     2221 gcttaaaaga attcggacaa gcaaaagcag aactgctcga ttggggagat atcagaggat
     2281 tcaaaacaaa gtttctacgg actttggcat ctcattatct aactgaatta ctaacaagtc
     2341 atcaattcca cgaagaggct attagtaaag atggagaaag atatcgcaaa tatgccgata
     2401 accctatcaa acatccatta gccactaagg ataaaggatt ttattcagtt gattgtagaa
     2461 cggatttatc tgctctggaa ccaaacgaaa tcgcaaagat gctattaaat gttaatgacc
     2521 attcgaccaa tagctttatt caacagataa gacgttatat atcatctctt gaaagaccat
     2581 taacaacagc tcgtggtgat aagaagagct atatttacgc taacttcaat ccgaagtatg
     2641 ctcaatttgc gattacaatt ctaagaactt actacaactt ttgtcgccct tttaaatcag
     2701 cggataaaaa ggttttgaca cctgctcaaa gattagggat tacagataaa caatttgatt
     2761 ggaaagatat aatttatttc aaatgacaaa aagagcttgg agtaatccca agctcttgtg
     2821 ctttatcttt actgttcttc ttcaattaac gcacccgtta actcaataag ttttttcttt
     2881 catatacatg aaaatagtag ttatacggat ttttatcatt ctttatccct ttttgggcaa
     2941 atacctcatt ccattcctca taattcactt ctggaaaaaa agtatctcct tcgaattcat
     3001 gatgtatttt tgtgatgtac attttctcaa cataagggaa aaacaaatta taaatctgtt
     3061 ctcctccgaa aataaaaatt tcttcttcgt ttttacataa ctcaaaaaca tcttctattg
     3121 aatgaacaat ttcacaacca ttaaaggtaa accccttatc tctcgtcaga ataatatttc
     3181 ttctgtcagg taaggctctt ccgattgatt caaggttctt cctacctaat attatcggat
     3241 gtccctttgt agtattttta acatattccc agtccttggg aatcctccaa ggaatgtcat
     3301 tctctttgcc aatcactcta ttcttatcca tcgcagcaat caaagaaact ttcatttata
     3361 acacagcctt tttaactaat ttaccatcta atttcttatt tctatcaaaa aaccttttct
     3421 cattatcctg cccgttagtt gaataagcaa ttttttctat aagttatatt atcataatac
     3481 cacaaaatca caaattttca ttcaattatc attttcaatt gcattttata aatcattttg
     3541 tatgtaattt ggtatgtaag ttaaaatgaa aaaagtagtc cattttgaag tacattttgt
     3601 cattttgtac tccaaaactg aactacttac ttgcatatat acgcctttat agtggagtac
     3661 tacatttacg agattcggtt agagtatcag aaaaagaaaa aataaaagtt acagaaatgt
     3721 atacttcaat aaatggtgaa ttatgtaaga ttgatagagc ttattctgga gaaattgtta
     3781 ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg agatacaaaa ctattgccac
     3841 agagaaaaaa gattgaaaat ccgcaccctc tactacaaac aactgttgaa ccgagtaaac
     3901 ctgaacagag agaaatgttg cttgatgccc ttttggaaat ctcagatagt gatccgcttc
     3961 tacgatatta
//
LOCUS       DAIGUC010000124         3939 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.130, whole genome shotgun sequence.
ACCESSION   DAIGUC010000124 DAIGUC010000000
VERSION     DAIGUC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.130"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..716)
                     /locus_tag="NOB46_002802"
     CDS             complement(<1..716)
                     /locus_tag="NOB46_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1059685.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLY"
     gene            877..1566
                     /locus_tag="NOB46_002803"
     CDS             877..1566
                     /locus_tag="NOB46_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI1059686.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            1580..3082
                     /locus_tag="NOB46_002804"
     CDS             1580..3082
                     /locus_tag="NOB46_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI1059687.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3095..3571
                     /locus_tag="NOB46_002805"
     CDS             3095..3571
                     /locus_tag="NOB46_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1059688.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKYGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(3668..3778)
                     /locus_tag="NOB46_002806"
                     /pseudo
     CDS             complement(3668..3778)
                     /locus_tag="NOB46_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1308 a          549 c          713 g         1369 t
ORIGIN      
        1 atataaagtt gtgatatttt tccagctaaa gatccaccat taagaaattc ttcaatggct
       61 gtttgtaaaa ctaagtctgc agactttcct ataggtgaat gaatatagtt agttatagca
      121 ataatttttg cgccattttt tttagctatt ttcaatgaat cataagtatc tttcgttttc
      181 ccagataaag aaaaaatgat tactaaatca ttaactgtta ataaagaagc gacttgggct
      241 tgaaaatgag ggtctagtac agcttttgct tgaactccta cgcgaagaaa catattttct
      301 aaatcaagac tagtatttcc actagatccc actccaaata tatatatgtt ttttgattga
      361 gtgatcattt taatggcttc attcaatttt tcttcgtcta aaagcctaat agtggaatag
      421 agagcttctg ttaaactatt agcaatttca tcatagtact ttacactagt cggatgttct
      481 tttttttgac taaagtcttc ctttgcaatt tcaattttta aatcagaaaa accagaaaaa
      541 ccaatttttt gacaaaagcg aataatagta gcatcgccaa cttttgtgtt tttcttaata
      601 tcactcatcg tactataaat aatagttttc ccagaattta aaataaaatc agcgactttt
      661 ttttcagact tcgttaaaaa tggataattt tctttaatta aatagatata actcatacaa
      721 actcctctac aatttcaact tttctccatt atactccaaa ataataaaaa aaactcctaa
      781 atactccatt tttatcttta cttttatgaa agcggatgct atattgtttt tggagttgtt
      841 atccaaaaat aataaaaaat tggagtgttt aggataatgg ataaaaagag gtttttagat
      901 cttatttcaa aaggtttgat tgtttcctgt caagcattac ctggtgaacc attttacaaa
      961 gaggaagaaa gtttaatgcc ttattttgct ttggctgctc aaagggctgg agcagttggt
     1021 atacgtgcaa attctgttcg agatattatt gaaattagaa agtgtgtatc attaccaatg
     1081 attggaatta ttaaaagaga ttatccacca gaatctccat tcattactgc cactatgaga
     1141 gaagtagatg aattagtaga aaccggtgtt gaggtaatcg ctcttgattg cactcttaga
     1201 aatcgacatg atggactatc tataaattct tttattacta aaataaaaga aaaatatcct
     1261 catcagttat ttatggcaga tatttctaca tttgaagaag gcaaaaatgc atataaagca
     1321 ggaatagatt ttgtaggaac tactttaagt ggatatactg aggaaagtaa aaaacaagat
     1381 gggccagata tagatttgat taaaaaattg gtagaagaag ggatttgtgt aattgctgag
     1441 ggaaggattc atactccaga acaagcaaaa gagataaaaa aaataggagt tgcaggtatt
     1501 gttgtgggtg gtgctattac tcgaccacag gaaattgcat caagatttgt taaagcatta
     1561 agttaggggg agaaataaaa tgtttaaaaa attttcacaa ttaggacgcg ctttcatgtt
     1621 accaattgct atattaccag tagccggatt actattggga ctgggaggag cgttaacaaa
     1681 tgagagtgct ataaatgctt atccattttt agatcaaccg tggttgcata caattttaag
     1741 tattatgagt tatgctggaa atgcagtttt tgcaaaccta gcactaattt ttgcaattgg
     1801 tattgctgta ggacttgcaa atggagataa aggaacagct ggtttagctg gtggagtagc
     1861 ttatttagta tatactgcaa ctattagtgg gtttcttgaa cttttttcag caaaagatgc
     1921 aacactagat acaggtgtag tgggatcaat tgttgttggt ggtactgttg catttttaca
     1981 caatcgttat agaaaaattg aattaccaca attcttaggt ttttttggag gatcaagatt
     2041 tattccgatt gtttctagtt tagctgcaat cattattggt tctttctttt atttaatttg
     2101 gccaccaatt caaaatggtt tagtagttgc tggtgaacaa attgcccaaa tgggtagttt
     2161 aggaactttt ttatatggtt ttttattacg tttaacaggt gctgttggac tacaccacac
     2221 catttaccct ttgttctggt atacatcttt aggtggtacc gaaactgtag ctggatcaac
     2281 aattgctgga gcccaaaata ttttctttgc ccaactagct gatccaaacc acactggtct
     2341 gtttacttat ggtactagat tttttgcagg aagatttgca acaatgatgt ttgggttacc
     2401 agcagcatgt tatgcaatgt atcgtgcaat tcctaagaaa aatcgtaaaa agaatggtgg
     2461 gctttatttt agcggggccc ttacatcatt tttaactgga attactgaac cagttgaata
     2521 tatgttttta tttgttgctc cttggcttta tgtgattcat gcattcttag atggattatc
     2581 tttttatttt gctgatatct taaatattcg tgtagggaat tccttttcag gtggtttgat
     2641 cgacttttta ttattcggtg tacttcaagg gaatgacaaa actaattggt taaaattaat
     2701 tccttttggt attgcatggg catttatata tttctttgtt tttacattct ttatcaaaaa
     2761 atttaaggta gctattcctg gaatggaaga agaatcagaa gttcattctg aaaaagtaat
     2821 aaacaaaaat acatcattac atgaagagtc tcttatcatt attgaagctc ttggtggaaa
     2881 agaaaatatt gagtctgttg aagcttgtgc aactcgtttg cgtgttgctg ttacaaatgg
     2941 ggagattatt caaaaacaaa caataaaaga cactggtgca actgctgtct tcgaagtgaa
     3001 gggtggcatc caagctgttt ttggagggaa agctgactta ttaagtcaag aaatcaatca
     3061 aatattagga aaagataatt aggaggtttt taatatgttt gaaattttca aaaagaaaaa
     3121 acaagaaact ttttatgcac cttgttccgg aaaaatcatt tccatcacag aagtaaatga
     3181 tcctgtcttt tcacaaaaat tactaggtga tggttttgcc gtcatacctg atggttcaaa
     3241 aatttatgct ccattggctg gtcgagtaac aaatatattt cctactaaac atgctattaa
     3301 tataaaaagc aactcaggca ttgattattt gattcatatt ggaattgata cagttgaatt
     3361 acaaggagag cctttttcga tttgtgttca agaaaatgat gaggttactc ctgaaacctc
     3421 gttggttgat gtggattttg acaaaataat aaaatatggt aaagatactt ctgttatagt
     3481 tgtttttccg gagaaaaatc agttcaatga tttaataata gataatggtc gaattgctca
     3541 tgggaattca tgtggaaaaa tcacttttta aaaaagtgta tataaaaagc tataaaataa
     3601 gctaaatagg atatttgtca aatgaagttg gtgaacagaa agaactgttt tctttctgtt
     3661 cattttttta ttttattagt aatgattccc catgccaaat catgatccgt aatttaaagt
     3721 tataaaagct tcgaaatcca ttggcatttc gttggaatac cttgatatga ttattcaaat
     3781 ataaaatata gagagaagag agagagggaa gatatttata aagggcaaag ttatgtttac
     3841 tcaacttagg aaatagaaat agatcaattt atattctctt gtcaatcgaa tatgaacctt
     3901 agcactatat accaaatata gtaaaatgct gaaagatgt
//
LOCUS       DAIGUC010000125         3894 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.131, whole genome shotgun sequence.
ACCESSION   DAIGUC010000125 DAIGUC010000000
VERSION     DAIGUC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.131"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..353)
                     /locus_tag="NOB46_002807"
     CDS             complement(<1..353)
                     /locus_tag="NOB46_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059689.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRT"
     gene            complement(613..1161)
                     /locus_tag="NOB46_002808"
     CDS             complement(613..1161)
                     /locus_tag="NOB46_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059690.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1162..2019)
                     /locus_tag="NOB46_002809"
     CDS             complement(1162..2019)
                     /locus_tag="NOB46_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI1059691.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2305..2592)
                     /locus_tag="NOB46_002810"
     CDS             complement(2305..2592)
                     /locus_tag="NOB46_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1059692.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(2582..2911)
                     /locus_tag="NOB46_002811"
     CDS             complement(2582..2911)
                     /locus_tag="NOB46_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1059693.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2988..3260)
                     /locus_tag="NOB46_002812"
     CDS             complement(2988..3260)
                     /locus_tag="NOB46_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI1059694.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3260..3523)
                     /locus_tag="NOB46_002813"
     CDS             complement(3260..3523)
                     /locus_tag="NOB46_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1059695.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            3757..>3894
                     /locus_tag="NOB46_002814"
     CDS             3757..>3894
                     /locus_tag="NOB46_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI1059696.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT         1165 a          784 c          498 g         1447 t
ORIGIN      
        1 aatgttctta ctgcctcttc cacactaatt tcttcgttca atttcactaa taatacttga
       61 tctcgcttat tataatcgct ttcatttatc ctaagagtca aatctttttc caccataact
      121 tttacaccca ataaattttg cggtttattt ttctctgttg aaattctttg tgtagccttt
      181 aaactgacaa ttagctcatt gggtacatac tctatttgag agtcatctaa ttggctcata
      241 atcctttctt tttggttagt atctgcagtt acttgtttag tatgagccat gaacccaaac
      301 atactcaccc caacaaccaa tcctaaatat attttctttt taaacttttt catctacatc
      361 tcctcctaat agttttattt tagagttagc tctattactt atttactaac tcaacaacag
      421 attatcatac acttgttaat gaaatcacaa tatctcatta aaacacaccc taaaatcata
      481 accgttccta tgctcatttt ttggattttt taatcacgta accagaaaaa taaatcccct
      541 ctatttcacg caaatcaaag aagaactaag taactaccgt ttaaaggtag ttacttagtt
      601 cttctttgat tattatctaa ctttattatt cattccccac cctttgcgca gtgagtcttc
      661 ggtatcttgt tttatctgac tggtagttct tattatttct ccacgatcat ctaattctgg
      721 aacaattgga tatttttctc tgaacaagtc tagttctttc accacgtcat taaacaaatc
      781 ttgcttatct tcttgcgtaa gattctgttt aatatactca tctaaagctt ttctaagcaa
      841 ttcatctctt gtcatattag tctcatactt ttctactaaa actctggaag tcgcatttaa
      901 caaagtcgac agttttaaag gatgcttggt ggaataaacc ttatcaaact ttctgattgg
      961 tgcgccaact ttttttgttc ttcctctact ctgtctttca acattggagg aagtttttat
     1021 ttcttgaact tggtgcactt ctaattgctt attttcagat ggtgtaattg cttgctgctt
     1081 tttctttgct tctgcttctt tttttatttt ggcgagtcct ttgttgttcc caaaaatatc
     1141 aagtcctttg atgtcagcca attactccac ctccgcatac caattctcgt gttcttccaa
     1201 ttctttcaaa atactgataa ataattcgtg gcttttgcga tcccattgtt ttaagagacc
     1261 tttctttgtc ttctccatcg taatacctga tccgtcgtat cgttttaagc gcgcattttt
     1321 gagtacaaca tttttaatca aatgttcccc ataaatctct tgggcttgtt tatacatttc
     1381 ctgatctact gcgtcaccgc tttccaacat gaaaggaata acaccagcaa catataaatt
     1441 tgtatcaaat tctttcacaa aaaagtccat atactcaaga tattgcatcg catttctcat
     1501 cgattttact tgggtctgta agacgacgat tgcccaatcc gcaatgtaca tcgcggattt
     1561 actatataca gaaatagaag gtgggacatc taaatagatg acgtcaaact catcaaataa
     1621 tggttctagc ttttctttca tatatttgaa ttgggataat gaatcattat attggtcttt
     1681 gatccaatca tcatacattt caaaggacat gtctgctgga agtatataga ggttattgat
     1741 tactttatag acagcctctt taggtggaag attgtttatc aacacgtcag tcacagtatt
     1801 ttcgtaaaca atcggttcac cttctccgcc tccttcttcg ttagtgaagt tcatatgcgt
     1861 taagttcatc acatcagaag tatttccttg catatccaag tcaattatca aggttctttt
     1921 tccttcatta actgctgatt caaaccctaa catttgcgcg cacgtacttt tacctacgcc
     1981 acctttaaaa ttaccgatta catatttctt cgctaccacg ttcctacctc ttttctttta
     2041 gcaatattca tttgatacta ttataacata tttattttta gttactacca aaaaaaagat
     2101 atatatgtac taccttataa ttaataagta aaaggtagta cataaataag gaaaagctga
     2161 aatatattga tttatagctt tcctcaaagt aatgacgtta tttaatttat cgagaagcag
     2221 agaatactcg cgactttagt catgtagatg aatcagatct tcgataaaaa agaagccgtc
     2281 cttcttaaga acgacaacaa atcactagat taattttttc aactgttcat aaaagttttc
     2341 atgcgttcca cataacaata ctggaataac cttgttttct ataatctcgt aagctactct
     2401 atatgttgtg cccgcatatt tgaacccact agaccaaata cctgataaat ccccagtttt
     2461 ttgttcaccc ttatatggat caatcgcaat ttcatcataa attaaattca aaaatttttc
     2521 tttcaatggc ttctctttta gcttttttaa atacttaatg acatgttttg aaggaacgat
     2581 ttcataagcc aatttctgtt gccaactcct ctttagtcat tactttagaa ttagtaagtg
     2641 tatcttcagc aatatctcta aaggaagaat gcattttgtt ttttctattc ttaaattcta
     2701 caagaatctc atctttatcg tagccttctg caattatatc agacaaaata tcttcgctaa
     2761 aatcataaaa ttctttttgt ggttcaacaa attcataaag aataccattc tctaccaact
     2821 ttgcttcaac ttcgactcca ttaggaacat taaaatcttt aggtactgtc aacatgattg
     2881 aattgccttg ttttcttgtt tttgtaatca tttaaatccc tcatttctaa cagtatgtaa
     2941 ttacttagta aatacattat accacgagat aatgtattta caagtaatta ctgtgactcg
     3001 taatgcgtcc ttgctgaata aatttcaacc acgtgttcat cttcatctac cttataaaca
     3061 acccggtgtt gtctattcaa tcttctagaa tacctacctt catgtgtagg ttttaacttc
     3121 tcaaatgatt gggtagggag atagggatct tcctttaaag tctgaataac cttctcaaat
     3181 tgaggtttca aattagactg tttgattttc tttaaatcag ctttagccga gtttttaatc
     3241 atcacagaat agttattcat tataagttat cccaatcaat ttcatcaaca ttagtaaatc
     3301 cactatcatc tttttctcgc ttacgaacaa cacccaaagt gcctatttgc tcaagtaata
     3361 gcgtttcttt gattgctttc caatcatcca aaccaataag caccgcatta ttttcactgc
     3421 gctcactaat gatttcaatt tccgtatgat tctcatttac atctttcaac aacttataaa
     3481 aatttttccg tgctgagcta ggatttaaga ctgtttttgc catatctact ccccctctaa
     3541 tttatatctc cattctaacg tacttaatta agtacgtaaa ttcgattgtt ttgtttaaat
     3601 tggagtacca aaacagcatt gtaaagtgtt atccgtttcc tttatacccg tggtgctagt
     3661 taattttttc ctagaggaaa atgtctaaac atgttggtaa atcaacaaaa aaacgcatag
     3721 agtagtctca aaactcccaa gaaatgagga ctacatatgc gttcatcaaa atatactgaa
     3781 cattatacag atacttttat aacattcaag gaaattatga gaactgtttc taacatatac
     3841 cacaattgtg taccagataa gattaaaaac cgaagaaata ctgatcaact gaag
//
LOCUS       DAIGUC010000126         3876 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.132, whole genome shotgun sequence.
ACCESSION   DAIGUC010000126 DAIGUC010000000
VERSION     DAIGUC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.132"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(716..3865)
                     /locus_tag="NOB46_002815"
     CDS             complement(716..3865)
                     /locus_tag="NOB46_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HCI1059697.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          635 g         1362 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccct
//
LOCUS       DAIGUC010000127         3754 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.133, whole genome shotgun sequence.
ACCESSION   DAIGUC010000127 DAIGUC010000000
VERSION     DAIGUC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.133"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            40..783
                     /locus_tag="NOB46_002816"
     CDS             40..783
                     /locus_tag="NOB46_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI1059698.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            798..1790
                     /locus_tag="NOB46_002817"
     CDS             798..1790
                     /locus_tag="NOB46_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI1059699.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            1802..2539
                     /locus_tag="NOB46_002818"
     CDS             1802..2539
                     /locus_tag="NOB46_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI1059700.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            2529..3251
                     /locus_tag="NOB46_002819"
     CDS             2529..3251
                     /locus_tag="NOB46_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI1059701.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(3335..>3754)
                     /locus_tag="NOB46_002820"
     CDS             complement(3335..>3754)
                     /locus_tag="NOB46_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCI1059702.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         1186 a          651 c          807 g         1110 t
ORIGIN      
        1 gttttttgtt attcatatta gaagaaagga ggtaacaaaa tgaagaaaaa tctttatcca
       61 gcagtcagta tggcattcat tttaattatt tggcagattg ttgtcatagt ttggaaaata
      121 cctgccttta ttttacccgg acctgctgct gtattttctg cattagcggc agatgcacaa
      181 gtattacttt cccattctgt cacgacatta aatgaagcag tgcttggttt ggtaatagct
      241 agcgttcttt cttttattac tgccttggca atggattatt ggaagttttt agaaatgtct
      301 ttttatccgt tactagtgat ttcacaaatg ttgccaatca tggtgttagg gccattactt
      361 accctatggt ttggtttcgg tatgcttcca aaagtgatcc ttgttgtctt gataagctat
      421 tttccgatcg tagtttcttt ttcggataca ttgaggaaag tatcaaaaga gcaaatcatc
      481 tttttgaaaa cgatgggggc agatacaggg aagatttatc gaatatataa aataccagcg
      541 ggtttatccg gcttcttttc cggtttaaaa gtggctgcta cttattgtgt cagcggagca
      601 gtcgttggag aatggctaag cgctcaagca ggcttagggt attacatgat acgcgtaaaa
      661 aacagctacc agatcgataa agtttttgct gcgatcattt gtgtcattct attgagttta
      721 ttgctgaatg gcgcttgttc attattgaaa aaagggtatt atcgtatgct ttatattttt
      781 taagagaagg ggatcaaatg aaaaaattat ggcttttatt accgctactg ttgcttttat
      841 ccgcttgtgg cactgcaaaa gaaacaagta gcaaacaaga aataaaggat ttgaaaaaag
      901 tgacacttgt tttggattat gtaccgaata ctaatcatac tggcatctac ctagcaaaag
      961 aaaaaggcta ttataaagag gctggtttaa atgtccaaat catcgaacca ggagataatt
     1021 cgacaagtat tggtctagta ggtgcggaca aagcacaatt tggtgtaagt tatcaagaag
     1081 atgtcactta tgctcacgca gatggacaga atataccagt caaagcaatt gctacagtga
     1141 tcaaacataa tacttctgga ttcgccaccc tatcagacag taacatccat tcaccaaaag
     1201 attttgaagg aaaaacatat gcaggttggc aaagtccaag tgaagaagct gtcttaaaag
     1261 ctgtgatgga aaaagacggc ggggactttt caaaactgac aatggtagga agcaatggag
     1321 aagggccaga aagcttagga aaatcctcag atatccaatg gtactttgaa ggttgggata
     1381 tgatcaaagc aaaagaagcg ggtattgaac taaactatat cccattgaaa gaattagatg
     1441 aacggttaga ttactatact ccggtaatta ttacgaatga tcaactgatc aaaagtgatc
     1501 cagaattggt acagtctttt atggatgcca cgaaaaaagg ctatcaggaa gctattaagg
     1561 atccaaatga cagtgctaaa ctgttgcaaa aatatgcaaa agaaaatgat cggacgtttt
     1621 tagaagaatc acaagcattc ttgtcaaaaa attatacgga tgatcctgag aattggggat
     1681 tgatggaaga aaaagtttgg cgcaattata cagcttttat gcaggaaaac ggattgatca
     1741 agcaagatgt accttcgcaa gaactattca ctaatcagtt tataaaatag gagtgataga
     1801 tatgtcaatc caaatcagcc acttgaatgt agtcattgaa aacctgaaaa tattagaaga
     1861 catccatttc actatcccta aagatacctt tacatcgatt gtcgcgccaa gcggagccgg
     1921 taagtcaaca ttgctgaaaa ctttaacagg agtccagcct atgacttctg gaacgatcaa
     1981 agtagacgat caaaaagtaa ctggtctcca tacagcattt agttatatgc cgcaagaaga
     2041 tatgttactt ccttggctga gcgtctatca aaacgttacg ttatatcaaa aaatcaatca
     2101 tctaacaatc aatgaagaac aagtaaggga ttatctggat atctttgggt taaacggcta
     2161 cgaacatttt ttgccggaac aattatctgg cgggatgaag cagcgaacgg ccttgttacg
     2221 aacaatcatg aatccttctt cttacttgct tcttgatgaa ccatttggag cgttagatgc
     2281 tatgaccaga gggcagatgc aagactggat gttgaagctg cctaaaaaag caaagcggac
     2341 tactttactt gtgacgcatg atatcgaaga agcaatttat ttatcagaca ggattcttgt
     2401 gctttccgcc cgtccggcac atgtgattgc tgagattcaa gtgcctgaaa aacgacggtc
     2461 acgtgaatgg ctactgcagc aatcagagtt gaagcaaacg atttatcagt tattggcagg
     2521 tgaattagat gttaagtgat gctcattgtc atttagatgg gagtcagagt ttagcactcc
     2581 ttcagcagga acacacgatt ttgacgatca tcaattgtga ttcgccagaa gaatggaagg
     2641 aaaacagaca gcttgcagca agtaagactc aagccttaag ttacggtatc catccttgga
     2701 aagcagatag ctatacgttt gaacaagttg agcctttttt gaaaaaagca aggatcatcg
     2761 gtgaaatagg gttagataat atttggacga atgtaccgat gactacacaa aaaaaagtat
     2821 ttgagcgaca gcttgctttt gcagccataa atgagaaacc tgttgtactg cacacaaaag
     2881 gatgcgaaaa agagatctta aattatatcc aagcttaccc taatcactat ttgatccatt
     2941 ggtattcttc tttggactat caacaagact atattgattt aggctgttat ttcagcattg
     3001 gtcttgattt gaaaaagaat ccagcagtct ggcaactagc taaagcagtc ccaatcgacc
     3061 acttacttat tgaaacggat ggactacatg cagcagagtg ggctttaggg gggatttttt
     3121 cagaaaaaga ttatgtctca ctgcttgaag aacagttaaa gacaatcgct gagatcaaag
     3181 agctatcagt tgaagaagtt aaaaaaaata cttatcaaaa cttggaacgt ttcattagat
     3241 taggtaaata aaaaagagat gtgacacaac tagtgtcgca cctctttttg gctttctttg
     3301 tataaaagta aactgtttga ttaataaatg aatcttagta ccaaccgttt gcttcccaga
     3361 atgctttcgc cgcttcccaa gaaccataac gtgaagtaac atattgttct gctactcttt
     3421 cttggtttgc agcagagtag tcaccattta agtaagaaga atctaattgg taacgtccga
     3481 tgtaacgtcc gttcgttgct gtgtaagaac cgcttgattc tttttgtgcg atccattctt
     3541 ttgcagagct tgtgcttgct ggagtagcag cagtttctgt tacagcagga gcaggttgtg
     3601 tttcagcaac aggcgctgct tgtttttccg tttgaaccgt ttcttgtaca acaggttgtt
     3661 cagcttggac tggtgcttct tgaacggctg cttgaggttc agcagctgct tgtgcagagc
     3721 cttctgttgg gattgttaat tgttgtcctg agta
//
LOCUS       DAIGUC010000128         3666 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.134, whole genome shotgun sequence.
ACCESSION   DAIGUC010000128 DAIGUC010000000
VERSION     DAIGUC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.134"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(130..429)
                     /locus_tag="NOB46_002821"
                     /pseudo
     CDS             complement(130..429)
                     /locus_tag="NOB46_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
     gene            617..1786
                     /locus_tag="NOB46_002822"
     CDS             617..1786
                     /locus_tag="NOB46_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1059703.1"
                     /translation="MNDFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            2091..2783
                     /locus_tag="NOB46_002823"
     CDS             2091..2783
                     /locus_tag="NOB46_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI1059704.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKIHNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            3211..3603
                     /locus_tag="NOB46_002824"
     CDS             3211..3603
                     /locus_tag="NOB46_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059705.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
BASE COUNT         1430 a          470 c          569 g         1197 t
ORIGIN      
        1 taaaatcttg atttaactag tttttttctc tcgtcttttt tatagatatg tataccttcg
       61 aaaagacaag aaataaaata gaaatacctg tttagtgcaa aatgagaaga atctttttta
      121 attcatagtt tataatttat ggatttctga tttagtcgta ggtgcatttt taatggtatc
      181 agctaccgga caagtacgat caataaatgc gataaaatct gaaatctctt catcagtatt
      241 atcagcttca atataaaatt tagatacgat tgcagaatag cctattttag ctgctttatt
      301 ttttcctata aaaccatcag gatctaatac tccatctatc tctacacgga tatcgtttaa
      361 atttatgccc tgcactttag cgaaagaccg agctacaata actttacatg ctccaagaga
      421 ggctaataat aagtattgga gatggtgcga agtaagattg ataaaaaatg gataaaggat
      481 tagatttaat acaatgtctt atcacgattc taatgatttg atgagagtgt aaaatatttt
      541 gtgtaaatag aaaaaaggaa gtcccttctg tagaatagag ttaccacaac acattcacag
      601 aaaagaggac ttccatatga acgattttac tacagaaatt atggaaacac taatcaataa
      661 aggtgattta gatgaattat ttcgatgtca tttagaatta gctgttaatt cattattgca
      721 ggctgaatta acagcttttc ttgattatga aaaatatgat cgtgctgggt tcaattcagg
      781 taattcccgt aatgggaatt attcacgttc attcagaaca gagtatggag aattaaattt
      841 ggtgattcct agagatagaa atggtaagtt ttctcaacaa actttacctg cttataaaag
      901 aaccaatgac tctttagaaa ccactattat tcagctattt caaaaaggaa ttactatgtc
      961 tgaaatctct gaattgattg aaaaaatgta cgggcatcac tatacgccac aaaccatttc
     1021 aaatatgact aaaatagttt ctgaagatat tattgccttt aaagaaaggt ccttagaatc
     1081 cagatactct gttattttta tggatgctac tcacattcct ttaaaaagac aaactgtttc
     1141 aaaagaagca gtttatattg taattggcat tcgattagat ggaaccaaag aggttcttgg
     1201 gtttagtctt gctccaactg aatctgctta tgtttggaaa gagattcttc aagacctaaa
     1261 agaccgtggt ttaaaagagg ttttattagt cgtaactgat ggtttaagtg gcattaacga
     1321 tagtattcat agtgtttatc caaatgctca atttcaacaa tgttgtgtcc atatatctag
     1381 aaatatcgct cataaggttc gtgttagtga tcgacaagaa atctgtagcg atttcaaatt
     1441 agtttatcaa gcaagttcaa aagaagaagc aaataatcaa ataaggttta tgatagataa
     1501 atggaaaaag cagtatccac gagtggttaa attgctcatg aatcctgcta tattaacctt
     1561 ttataatttc cctccgtcaa tcagaagaac tatttattca actaatttga ttgaaggttt
     1621 taacaaacaa ttaaagaaat ataccaaaag aaaagagcaa tttcctaatg aagaatctct
     1681 ggagagattt ctagtatctc aattcaacaa ctataatcaa aagtttctat gccgagttca
     1741 taaaggtttt aaagaaatac atgatacatt agaatcaatg ttttaacttg atcaacagaa
     1801 tgggcttttc catttacaca taattcttga cgcaacctat tctggaaact tacaaataaa
     1861 agcttattct tcagccacct tcgggtggtt attttttata aaaaaatgta aaaaaatatt
     1921 gatacataaa taaattagtt gtagtaaata gttttagaat tgaatttctc tatccttttt
     1981 aaataatttt ttagacaaaa aacagaaagt gtctaaagaa agcttgacga agaaaataat
     2041 ttttaataac ttatttaagg taagaaaatt ttttgaagga gaagataaaa gtgagaaaaa
     2101 agattattat taatgctgga gtaattatag gattgatgtt agtaattttc tccggaaagc
     2161 aatatgctga taatatttta ttatggggag gggaagataa tattgaaaag atccacaaca
     2221 atttaactat attagacaca gctctagaaa ataaagagca aaaaattagt attttaaatt
     2281 cacaattgtc ttcaaacaac caaactcttg aacaactaag aactaatatt gaagtttcca
     2341 aacaaaaagt ggcatcttta gaaaacgaca agaatcaatt agtatcagag aaaactaatt
     2401 tagaaaatca attgtcagca aaagactctg aattgcaagg aaaacaaaat gaaattaatg
     2461 cgaaaataga cgaaattaac caaaaagtag ctgaaataaa tcgattaaat agcgattgga
     2521 ataatcgttt acaaaatgaa aagaacaaat ttaatgaaga acaatctact attaatagtt
     2581 taaaccagca aattaatcaa atgttgagtg aaaaaaataa cattcaaaat caactgcaag
     2641 ctactcagca aaagctagaa gaagaaaagt caaaaaatag tagtttgaat aattacattg
     2701 aaaagcttca aaaagctaaa aatgatgtag aggataccgc aaataaagca caacaaattg
     2761 taaatgaaca tacaatccaa tagatatagt tttaatttaa caaatggtat gtttggagat
     2821 aatgagatag aatataaatg tcataatatt atacaatcta aacaccgttt ccttttctat
     2881 ttttgatgac atcagtatat agctactcga aagagtagtc tttttattat tctcgcttat
     2941 tattgatatg aaaatttcga tttgacaaaa ggtaccgaat aattttgtaa tatgaattat
     3001 tatcaagaag taattatgat gataacatat ggaaactagt tagtaataat cacaggtgat
     3061 taaacttttg aacgacttgt aattctatat tttttctttt aagtaaaaaa tataggtgag
     3121 tttttttgac ttcatattta taataaagac acgtaaatca attatttttc attttacttt
     3181 aactaataat gtttatttgg agggattatt atgttagatg atagattgac gtgttctaat
     3241 tgtggtacat tattttacta tgaggaagtt agaaatattg taaaacatag aaaaaaagaa
     3301 atgcctatac gttgtccaaa ttgcaatgaa gttattaagc gaaagttgtc tcatggttat
     3361 tttgtcagct acgaactata tgaagaaagt aaaataaatc tgaaaaaaaa accaaaatac
     3421 tataaaaatt tgaaaactgg agctattata actgaaaaag aatttaaaaa tttagtgact
     3481 gaagaagaaa gcaggtttta taatttgtct ggtaatattt gccctggatt tatggatcag
     3541 attattgaaa atgagtcaat tgaatcaatt gaaaactatg ttcctgttga cttaccaaaa
     3601 tagaaaaaat aatcctgttt ttacagtgaa ttattttaat tttgattttc aataaaaata
     3661 tattac
//
LOCUS       DAIGUC010000129         3219 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.136, whole genome shotgun sequence.
ACCESSION   DAIGUC010000129 DAIGUC010000000
VERSION     DAIGUC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.136"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            50..1438
                     /locus_tag="NOB46_002825"
     CDS             50..1438
                     /locus_tag="NOB46_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HCI1059706.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3219
                     /locus_tag="NOB46_002826"
     CDS             1776..>3219
                     /locus_tag="NOB46_002826"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCI1059707.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1183 a          505 c          583 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaag
//
LOCUS       DAIGUC010000130         3189 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.137, whole genome shotgun sequence.
ACCESSION   DAIGUC010000130 DAIGUC010000000
VERSION     DAIGUC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3189
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.137"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            2..586
                     /locus_tag="NOB46_002827"
     CDS             2..586
                     /locus_tag="NOB46_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI1059708.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(663..1856)
                     /locus_tag="NOB46_002828"
     CDS             complement(663..1856)
                     /locus_tag="NOB46_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI1059709.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1920..2300
                     /locus_tag="NOB46_002829"
     CDS             1920..2300
                     /locus_tag="NOB46_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCI1059710.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2374..2736
                     /locus_tag="NOB46_002830"
     CDS             2374..2736
                     /locus_tag="NOB46_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059711.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1076 a          521 c          606 g          986 t
ORIGIN      
        1 tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg ttatcaaaac
       61 aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga cggttcaaaa
      121 tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc gcgttattcc
      181 tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg aaagtattta
      241 tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg gagctttatc
      301 tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa ataacacaaa
      361 tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag aaatcattga
      421 agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct ttggacatgt
      481 actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc cacaagaccg
      541 acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg gtatggtacg
      601 gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt tgaataaatg
      661 atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag taaagtttct
      721 tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa cgtgatgcca
      781 ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg gtcgtctgaa
      841 atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat tattctcact
      901 ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc tagataagga
      961 atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc aatcagtcca
     1021 aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc agctttcatc
     1081 tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa agtcttggtt
     1141 gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag catggaagta
     1201 aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag aatcacttga
     1261 tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac acgccctcca
     1321 ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat ttttttctcc
     1381 atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct tcgaacgatg
     1441 tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc atgaatcaaa
     1501 atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt taacacacca
     1561 cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg ttcccaatga
     1621 atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc atgtttgatg
     1681 tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc tgctacccac
     1741 aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt tacactttct
     1801 gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc agtcattttc
     1861 gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga gggaagtaga
     1921 tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag ccttatggcg
     1981 cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa gtacaatccg
     2041 gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca gttcagatca
     2101 tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta gaaaaaacaa
     2161 atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt aagatcggat
     2221 ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct gaactagaac
     2281 ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga atttttatgt
     2341 aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt tgctggtaca
     2401 attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat tgatgacaag
     2461 ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa tatacttaat
     2521 ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga attgacaaat
     2581 acacatatta aagaggaaaa tgttccgttg tttgtctttg aaactgaaca aaagaatcaa
     2641 agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg ctctgttctt
     2701 ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc gaacaaagaa
     2761 gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac aatgaaatgt
     2821 tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa acggttgtat
     2881 aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa tttatagttg
     2941 accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga tgttatatca
     3001 catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg ataagataac
     3061 tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa cttcaaaaaa
     3121 gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag atttcgaaaa
     3181 acgaaatcg
//
LOCUS       DAIGUC010000131         3149 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.138, whole genome shotgun sequence.
ACCESSION   DAIGUC010000131 DAIGUC010000000
VERSION     DAIGUC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.138"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..1133)
                     /locus_tag="NOB46_002831"
     CDS             complement(<1..1133)
                     /locus_tag="NOB46_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI1059712.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL
                     HPNMCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQY"
     gene            complement(1149..1265)
                     /locus_tag="NOB46_002832"
     CDS             complement(1149..1265)
                     /locus_tag="NOB46_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCI1059713.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(1510..2442)
                     /locus_tag="NOB46_002833"
     CDS             complement(1510..2442)
                     /locus_tag="NOB46_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI1059714.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            complement(2439..>3149)
                     /locus_tag="NOB46_002834"
     CDS             complement(2439..>3149)
                     /locus_tag="NOB46_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI1059715.1"
                     /translation="PPNSLSTEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGG
                     FLGYVANRGNKYTFELAQSFSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVT
                     QYLVTTEFDDDTVQAIMDEALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPR
                     TAQQQYDVTQHIPLSEAQAGDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYAD
                     LTSPYWQQHLVGAGRIKQ"
BASE COUNT          891 a          650 c          529 g         1079 t
ORIGIN      
        1 taatattgta gaagcgggtc actgtcggag atttctaaaa gtgcatcaag taacatttcc
       61 ctttgttgag gtttgctcgg ttcaacagtt gtttgcagca gagggagcgg attttcaatt
      121 ctctctctct gtggcaatag ctttgtatct ccaagaacac tatttagctt caaaaactca
      181 ttttgcaaaa taacaatttc cccggaataa gccttatcaa ttttacataa ttcaccattt
      241 attgaagtat acatttctgt aatttttatt ttttcctttt ccgatattct aaccgaatcc
      301 cgcaaatgca ggattccgcc ataaaggcgt acatatgcaa gacgttgtct ttcttccgaa
      361 tattcaattt tgaagacatt tccgcaaagt tcagacttct ttctgtatgt tgatgaataa
      421 aatttattcg ttatcacttc tataagctgc tcaatcccta tgttgctttt tgcgcttcca
      481 tgataaacag ggtacaagga gcaattctga aatcttctga tttcctcttg ttcgagttct
      541 aatgcttcta atgatttacc ggacatatat ttctctaaaa ggtcatcatt tccttctatt
      601 accacatccc attgctcagg ttccgtacag ctcatcacac acatattagg gtgcagctct
      661 actttctgtt tgattataat ttccatagaa agtttctctt taatatcctg ataaaccgtt
      721 gataaatcaa ttccattttg gtcaatctta ttgataaaaa agattgtggg aatccccatt
      781 ttcctaagtg catgaaataa tatacgagtt tgtgcttgta cgccatcttt tgcagaaatc
      841 agtagaattg ccccatctaa aactgataat gaacgatata cttctgctaa gaaatccata
      901 tgtcctggcg tgtctatgat gttcaccttc gtattttccc actgaaaaga ggttattcct
      961 gtctgaattg taattcctct ctgacgttct aaaagcgtat tatccgtcct cgttgtacct
     1021 ttgtccacgc ttcctaattc tgtaatcgct ccactgttat ataataagct ttctgttaag
     1081 gtagtttttc ctgcatcaac atgagctaaa actccaatat taataatttt catgtgattt
     1141 tcctccattc aaaaacccaa aagggcataa aaatcccagt gataaatact tttatcactg
     1201 ggatttttat gcataaccat aggtatacaa agcatacaga tattctctgg atactttaga
     1261 atcacatgat aaaggtattc ttaaactggg tacaaaaaac taagccctcc taaaaaagga
     1321 catctaatta tttgttcctg ctatcaaatt gacagtttat ttaagaatac cttgccgcat
     1381 atttattaac tccttttaaa tagtcactta aataatagca cgtaagagca tatttgtaaa
     1441 ggaatctcca attttttatc aaaaagagta catgattaca aagtatctgt aatcatgtac
     1501 caatatttgt tattttacaa tcttccaatt actcccgttc ttttcaagta ccaaatcaaa
     1561 ttgagatacc tgcgttgctt tggtctgctg gtcgatatac tccactgtca gcgataccgt
     1621 gacttgatta tccttacgat tgtgaatagg atttaccagt tcttgaaaga tgtactcttt
     1681 tccgattggt tttaatatcc cgtcattcac atagtaggaa agttcactgg ctgtcgctgt
     1741 aggatagagc ttgaagaacg tcgttaaaaa ctcattgatt tcattggttg taatggaatc
     1801 aaccgtcccc tcactttcaa tggcttttgg tttataactt gatttcttag gtatgttggt
     1861 aatggtcgga ttcttaacca gtaccatatt tccagaacca tctacataga cactcactat
     1921 ataagcagag tggacggtct ttgtattttc tccctctgta atgagctggt ctacactgta
     1981 ggttacatta aactcattgt cgccagttgg ctctaccgtc catatctgaa atcctcttac
     2041 agaagacgat acaggaatat ctttgcgtac tgtatcaaca ttgagagctt gaagttcatc
     2101 tgtcagatag ccttttagac tttccattcg attatcaatg gacttatcgg attgctccca
     2161 tgaatagtag actttcgcaa agttctctac aaaattttct acatgatgag tatcaacgta
     2221 ttccttttct atgatagttg tttcgtgaat agtatgagta tctatagctg taaagtgctt
     2281 gaatatcgca aagctgaaac taagccctaa aagtacccac aaggcaatca caaccttttt
     2341 atgaggattg accttataga cacgaggttt cttttccttt ggtatctgtt tttctttatt
     2401 ctgatttttt ctaaatttca tcattaaatc ttcctttctc attgtttgat tcgtcctgct
     2461 cccactaaat gctgttgcca gtaggggctt gttaagtcgg cataaccgat tgggtcgcct
     2521 gcatgaaaca tacggttatt gccaaggtat atcccaacat gagtaatata agagccagcg
     2581 ttataggtag aatgaaagaa aaccaaatcg ccagcttgtg cttccgatag tgggatatgc
     2641 tgggtcacat catattgctg ttgtgcggtt cgtggtaagt taattccagc ttttccatac
     2701 gtccattgtg tcagtccgct acaatcaaaa gaagtagtcg gggaagctcc accgtaaacg
     2761 tatcgccagc cctcatattt cagtgcttcg tccatgatgg cttgtaccgt atcatcatca
     2821 aactctgttg tgacaagata ctgcgttacc agttgcacat aaaacatatt gccatagttg
     2881 tatcgccagc ccccattgat aggtatggct atgggattgg ggtaagacac tttttcgcca
     2941 cctgaatact cttttgagaa actttgagcc agttcaaagg tatatttatt tccacgatta
     3001 gccacatacc ctaagaaacc accaccataa ttgtaggact ggataaccga ttctaaatct
     3061 acactgagcc tttcgctact ggctaataat tcactgaaat acttcacacc ttgcttaatg
     3121 gattcttctg tactcaatga attaggtgg
//
LOCUS       DAIGUC010000132         2908 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.139, whole genome shotgun sequence.
ACCESSION   DAIGUC010000132 DAIGUC010000000
VERSION     DAIGUC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.139"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..330)
                     /locus_tag="NOB46_002835"
     CDS             complement(<1..330)
                     /locus_tag="NOB46_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepB"
                     /protein_id="HCI1059716.1"
                     /translation="MNKNITKARHFGFLLYPESIPENWREQLESLGVSMAVSPLHDMD
                     EKTNKKDWTSSDVIRNGKHYVKPHYHVLYIARNPVTIESVRKKIKRKLGNNSVAHLEI
                     IDHIKGSY"
     gene            complement(1047..1226)
                     /locus_tag="NOB46_002836"
     CDS             complement(1047..1226)
                     /locus_tag="NOB46_002836"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059717.1"
                     /translation="MEKDIYKQLTRQIQKEKEKGLLDHLDELELKADEINKNRMSAKE
                     KGIKLKDSSLQSDKS"
     gene            complement(1351..1596)
                     /locus_tag="NOB46_002837"
     CDS             complement(1351..1596)
                     /locus_tag="NOB46_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059718.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLKYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1941..2225
                     /locus_tag="NOB46_002838"
     CDS             1941..2225
                     /locus_tag="NOB46_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059719.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            2228..2644
                     /locus_tag="NOB46_002839"
     CDS             2228..2644
                     /locus_tag="NOB46_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059720.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNQPKNHQKGTNKTVTSSNFDPTKFLKR"
     gene            complement(2732..>2908)
                     /locus_tag="NOB46_002840"
     CDS             complement(2732..>2908)
                     /locus_tag="NOB46_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepB"
                     /protein_id="HCI1059721.1"
                     /translation="QEYGITNQRDVVDVIASNSNLFRMMFDANYQNGFRPQYAKRIDS
                     ETGEMIEGVNKHVE"
BASE COUNT          882 a          583 c          433 g         1010 t
ORIGIN      
        1 atacgagcct ttgatatggt caattatttc taagtgagca accgaattat ttcccaattt
       61 tctcttgatt ttctttctta cgctctcgat tgttacagga ttgcgagcaa tataaaggac
      121 atgataatgt ggctttacat aatgcttacc gtttctgata acatcactac tagtccaatc
      181 ctttttattt gttttttcgt ccatatcgtg taacggacta accgccattg atactcctaa
      241 gctctcaagc tgttctctcc aattctctgg aatagattcg ggatatagta aaaaaccaaa
      301 atgtctagct ttcgttatat tcttattcat gatatactta cctcaattga acactatcag
      361 ttaagcggaa acggtgcgcc aacacatatg tttctgctct ttttttgcgc tcaatttcct
      421 ttctctgatt ttttcaagtc ttctgttact agcaatttaa catatgtcga catactcaaa
      481 cttttgtctt ttgctttttc ctcaagtttt cgcttaattt cactcggtaa aattactacc
      541 agtctttctg attccgccat gcctttcagc ccctttagtt aattgttaat atcatggtaa
      601 acttttgaca actgtattgt caatattttt ttctattttt caaaacggcg gtcaaaacgg
      661 cggtcaaatg gcggtcgaaa aaaaaaggct ctatccattg gtacagtaag gataaagcac
      721 tttttggcac aaaaattggc actcggcaca ctatgggggg gtcgtagtag cccccccaga
      781 ttttccaaat tccaaatttt ttccaaaaat tttccagcgc tatcgctcgg caaatcaaga
      841 ccgtaccttt ttgaaaaaag gcaccccaaa aactttccac tcgccgttaa ggcgtcaaga
      901 acgttcccta tggtcacctt cttgtgtttc cagcttttgg gttttgttta tagccgtcaa
      961 ctccttaaag cctcaaagag acgctaagag ggcttattag cctctctaag cgtctctaat
     1021 tcgatttacc gttgaccgca cgttatctag cttttatcgc tttgcaacga cgaatcttta
     1081 agttttatac ctttttcttt tgctgacatt ctgtttttat tgatttcatc agcttttagt
     1141 tctaattcat ctaaatgatc tagtaagcct ttttcttttt ccttttgaat ttgtcgggtc
     1201 aattgtttat aaatatcttt ttccatcccc catcgcctcc ttaaaagcta ttattattcg
     1261 atttaagacg ttttatttag tttttggtgt tatttcattg gtccaagcta aaaaactctt
     1321 agaagcgatt ttagagccat ttaaacccac ttaattatat tctccatgaa attcgctcca
     1381 tgcgtcaaaa gctgcgtctg aaattccgcc gtcttcgttc actagttgca ttaatttttc
     1441 caacgatcgt tttctttcgg gcgtcatatt tttatatttc aacaattttt cgtctgttaa
     1501 atcgaacttg attgcttgaa ttgcttgctc taatttttct aagttttgaa aatattcgta
     1561 aggaaatttt tccatttttt ctttctccag tctcacaatt tttctagaaa taaaatcact
     1621 tctttgccgt ctatactctc aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc
     1681 gtgcattttt aaatttggtt atcgatcaca cgtgcagcac tcccccccga attttaaaga
     1741 gcataaggaa acgtggtatc actttcttac gaaaggtgct agataggctg tgcctatcac
     1801 gtttctttga aaaaaatttg atatcacttt ttcgccatcg tggatagctt atgtatagta
     1861 ttttggcaaa aaacagctat acaaatatag tatttgtatg gtatacataa attatacata
     1921 attgcaaaag gagatttttt atggacattt tagttcggaa tattgatcca aagtttgttg
     1981 caacaataga caaacgttgc caagaactca cgaataaaac aggagaaaaa tggagtcgaa
     2041 ataaatatct aaaagtttta atcgaaagtg attttgaccg tcaacttacg acttacaaaa
     2101 aagaccaatt cgatttattg ctcgataaat ttattgctat ccaaacagaa aatactcaaa
     2161 tattaagcga gtatgtctac acaaataatc aaatcattga aatgcttatc ggaggaatga
     2221 tataaccatg agaaaaactt ctgtccaaaa acatgttact ttgtacccta gtcatgttga
     2281 cgttttagat tccatcatcg aaaaaaatcc agatatcaat aactactcgg aagccattcg
     2341 ctttttatgt atgagttatg aacccgatac caacacgacc actaccagca atcaggcaaa
     2401 actaaatgct atgggaaaag aaatttccat catgactgaa atcatcgcag aattcgctga
     2461 tttatatcta aaagatacag gcgttcttat cggcacaaat tctaaagtat atcaagaagt
     2521 gaaagaaaaa atcgaagcta aactaaatcc atcaaatcga aatcaaccaa agaatcatca
     2581 aaaaggaaca aacaaaacag tcacttctag caatttcgac ccaactaaat ttctaaaacg
     2641 ataaaaaaca gataggagtt attcctatct gttttttatt tcccaatatt ctattttttc
     2701 attccaagca gttaacggaa gttttcgata tttattcgac gtgtttattc acgccttcaa
     2761 tcatttctcc agtttcagaa tctatccttt ttgcatattg cggccgaaat ccgttctggt
     2821 aattagcatc aaacatcata cggaaaagat tgctgtttga agctatgaca tcaacaacat
     2881 ctctttgatt agtgattcca tactcttg
//
LOCUS       DAIGUC010000133         2888 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.140, whole genome shotgun sequence.
ACCESSION   DAIGUC010000133 DAIGUC010000000
VERSION     DAIGUC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.140"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(28..1454)
                     /locus_tag="NOB46_002841"
                     /pseudo
     CDS             complement(28..1454)
                     /locus_tag="NOB46_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1697..2152
                     /gene="tnpA"
                     /locus_tag="NOB46_002842"
     CDS             1697..2152
                     /gene="tnpA"
                     /locus_tag="NOB46_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HCI1059722.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYRRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2417..2515
                     /locus_tag="NOB46_002843"
                     /pseudo
     CDS             2417..2515
                     /locus_tag="NOB46_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2738..>2888)
                     /locus_tag="NOB46_002844"
     CDS             complement(2738..>2888)
                     /locus_tag="NOB46_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HCI1059723.1"
                     /translation="QEPTESKRHRAQGIIKIAKRMFSIKGVLSYTVLIQKIPNHLVYK
                     NNVED"
BASE COUNT          886 a          518 c          533 g          951 t
ORIGIN      
        1 cttttttcat gctctaaaat gatattttta cacaactatt acggttgttt tacgaaattg
       61 gacgggactt tgccagttta atttctgttt tatccgttca ttattgtagt aatagatata
      121 gctatcgatg gctgatttta attcctcgaa acagttataa actttcccgt gaaaaatctc
      181 ttgttttaat aagccaaaaa aattctccat aagtgaatta tctaagcagt tccctttccg
      241 agacaggctt tgaaagattt tgtactcctt caatttgttt ctataagctt tcatttgata
      301 cgcccaacct tgatctgagt gaaacgtacg acgataagga caatcgttag tggtctggat
      361 agcttactcc aaactttcca ttaccgctaa tgcattgggc ttttcagaga tacgatagga
      421 taaaatctca ctattgaaca tatccataaa aggatctaga tacaatttct tttgacggat
      481 aatgcctttg gcatccactt catggtattt aaattcagtt gtatccgtcg tgattttctg
      541 atggcagata ctggtgtaga aacgacgatg gatccgattt ttggctactg ctccgacttg
      601 tcctcgataa gaattgtagc gccgtgattt acgtgtgtat gtcgttactt ttattcctag
      661 cttcttgatc aggcgctgaa ctttcttttt attgatagag aaaccgcggt ttcttagttc
      721 attggtcatc cgtaaacagc cataatcctt gtgcttctcc cgaattttaa gcatttccgc
      781 ttcaatctct tgatctggat ttttacggtc caatcgtttt tgccagtaca taaaggttgc
      841 cttagggaac tttaaagttt ctagaagctc aactaattta aacggtcctc ggaggcttgc
      901 gatgattcgt gcgattgctt cattcgtcgt tgttgggctt cctgttttcg cagcttcctc
      961 aattctttta aagaggcatt ttcaatttga agggaacgga ctcgtttctc caactcctcg
     1021 atgcgttcac gttctttaga cgttgcttta gttgtagatt ttttcttatt tttgggttca
     1081 tatttcttag acaagatagg tggacatcct ttcgtttttg agagtccatc gatcccaccc
     1141 tcacggaatt gatgcatcca actagcgatc aaattagggt tgttcatgtt aagtgtgttg
     1201 gcaacttcac gataggacag ctcacttgtt agatataact ctatcgcatc cagcttaaat
     1261 tgaacagaat attttttctt ttgtcgcttt cttactagac cctcttcacc aaattcttga
     1321 taggcattga tccagcgctt cacttgtgat ggaaccttaa tggaatactt ctttgccaga
     1381 taatcacttc cgcctttacc atccaaataa tcatgaacga tctttaattt aagttcaaaa
     1441 gtatacttag ctataaaaaa taccgacctc caaaagttag attttttggt ctaacttttg
     1501 ggggtcggta caaaacttaa aagttttaga cccttttatt ttcttaatga cttcagtcag
     1561 ttttgtgcgt aaagcgtgcg aaacaagaaa accgcgcgtt tctacgcgtg gaagaagtat
     1621 ctttagcgat aaaaactcct ttcgatatac tagtgagtgg ctaccaaccg ctcatcagat
     1681 cgaaaggagt tttttcatgt caaatgacga taaaagttta gcatatactc gttggaattg
     1741 taagtatcat attattttta caccaaaata tcgacgaaaa gtaatctatg ggcaattacg
     1801 aaaagatctt ggaaaaatac ttaggaagtt gtgcgaaatg aaagatgtgg aaatcataga
     1861 agcacatgca atgctagatc atattcacat gcttgttcga gtaccaccaa aaatatgtat
     1921 atccagtttt atggggtatc tgaaaggtcg tagtgcggta ctaatccacg agcagcacgc
     1981 aaatctcaaa tataaatacg gaaacaaatc cttttggtcg aagagatact atgtgagtac
     2041 agtcggattg aatcaaaaga caaatgaaaa atacatccgt gaacaagaag ctgatgatcg
     2101 cattcgatat attataagta aaagagagta cgtagaacca tttaaaaaat aaagagaagt
     2161 aagtgagtga agatgagcag ttggcggtct tttaaaaatc cccttttaag gggcagcgag
     2221 tgtcgacccc ttctaggggg attaaaaata cacccgtcct cacgggtgta tgggttactg
     2281 atagacttga ttttaactgg tgtcagaaac ttatgtccag aaagggtgat gaaattttgg
     2341 caatttacgg ctattcaaga attagcacaa gcaaccaaga ttacaaaaca caaattcaaa
     2401 cattagaaaa tgctggcgca gaaataatct tcctagaaaa tcactggatt atcgaacacc
     2461 tttggaagta tttttgagtt acgtaagtat tgatgatctg tctaacttaa tttgacaatt
     2521 aagagtatat ttacttcaga tggtaaggca acaaaataaa atacaatagg cagatgaact
     2581 aataaataaa atctgtatta aatacagata aattaatata aaaatcaaaa ggatcataaa
     2641 cttttaacaa gtgatgaaat gggtggaaat tgattcttat agacagtttg tctcataaca
     2701 ttgaagtatt ttgcaatttt agcattgaaa cactttttta atcttcaacg ttgttcttat
     2761 aaacaagatg attgggaatc ttttgaatta acactgtata gcttagaaca ccctttatag
     2821 aaaacattcg cttagcaatc ttaataattc cttgtgcccg atgtcgttta gattcagtag
     2881 gttcctgc
//
LOCUS       DAIGUC010000134         2865 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.141, whole genome shotgun sequence.
ACCESSION   DAIGUC010000134 DAIGUC010000000
VERSION     DAIGUC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.141"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            95..1054
                     /locus_tag="NOB46_002845"
     CDS             95..1054
                     /locus_tag="NOB46_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="HCI1059724.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINF
                     LKEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPIS
                     CSVRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEF
                     GHIEGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFK
                     SITFDCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQ
                     VDQAFISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
     gene            complement(1487..2059)
                     /locus_tag="NOB46_002846"
     CDS             complement(1487..2059)
                     /locus_tag="NOB46_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1059725.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2075..2680)
                     /locus_tag="NOB46_002847"
     CDS             complement(2075..2680)
                     /locus_tag="NOB46_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HCI1059726.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          918 a          581 c          471 g          895 t
ORIGIN      
        1 gccgattgta aaattaagct agacaaataa ataagccatt cgtgctacac tcaaaatgta
       61 attccgacta aagaaaacat aggagtgatc acgaatgacc tacacccatc ttaccacgga
      121 tgaactggtg atgatagagt cttactacca ccaaaacatc aaaattgtga aaattgctga
      181 gtacctgaaa cgatctcgaa caccgattta taacgtcatt aatttcttga aagaaggcca
      241 tacggccctc gaatactacc aacagtataa agaaaataag aaacggtgtg gcagacgaaa
      301 catcgtcttg ccaaagaaac aacagtccta cattaaagaa aaaattgccc aaggctggac
      361 gccagacgtt atcattgggc gtaaagagaa accaatcagc tgttccgtaa gaacccttta
      421 tcgccagttc aaggaaaagg tgttcgatga atcgactttg cccatgaagg gtaagcggaa
      481 accaaatgga catcaagaac gccgaggaaa acaggctttt aaacggaata tcgttgaaag
      541 agaaactgat tacccgacat ttaaagaaga gttcggccat atcgaaggcg ataccattgt
      601 aggcattcat cataagagtg ctgtcataac tttggtagaa cgtctatcga aaatcatcat
      661 caccttgaag cccgaggggc gcaaggcgat cgatattgag aatactctga accactggtt
      721 tggatcgatt cccagacatt tatttaaatc cattaccttt gattgtggga aagaattctc
      781 taattggaag gctttaagta accaacatga catcgctatt tatttcgctg atccagggac
      841 tccttcgcaa cgagcactga atgaaaattc caatggcttg ctgcgaaaag atggtctgcc
      901 aaaaaacatg gattttaatc aagtcgacca agcttttatc tcttcagtgg cgaataagag
      961 aaacaatatt ccacgaaagt ccttggatta tcaaacaccc ctggaagtat ttatgagtta
     1021 catgaatgaa gatattttgt ctagcttaat ttgacaaatc aaattattta aaactttgca
     1081 acagaacctt agcagcagtg ctgattttta tgatagttat ttggttctta aatgaaagat
     1141 ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca atagattatt
     1201 tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg aacgatatgt
     1261 gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc taatatagta
     1321 agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca cattttttga
     1381 gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag actcatatct
     1441 agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa ctttcttcaa
     1501 ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct tcaacttcct
     1561 tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt gtgattgttg
     1621 ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt tttccttctt
     1681 gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac gtccgtgtca
     1741 ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg atcgttacgt
     1801 tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga gcaaatcgat
     1861 caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc tgattgaatt
     1921 ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc ttctctacgc
     1981 cgttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt gagacacgtg
     2041 catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc gtatactcag
     2101 aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg cgatcgtcaa
     2161 ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt atgggacttc
     2221 gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca actttttgca
     2281 attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt ccttctcgaa
     2341 atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa gaagtttgtg
     2401 gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca aatcgaaaat
     2461 ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata tccgaaaata
     2521 gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca tttatttttc
     2581 cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc ttagccaact
     2641 caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc cttaacttta
     2701 tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt tatgtgtcaa
     2761 aaactattaa gtttctgacc ctctacaaaa ttcacaatag atataatcta ttgaaaattt
     2821 aaaagaagac aaaatagagt acagaaaatg ttttctgtac tctat
//
LOCUS       DAIGUC010000135         2492 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.142, whole genome shotgun sequence.
ACCESSION   DAIGUC010000135 DAIGUC010000000
VERSION     DAIGUC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.142"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(367..1659)
                     /locus_tag="NOB46_002848"
     CDS             complement(367..1659)
                     /locus_tag="NOB46_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1059727.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1933..2193)
                     /locus_tag="NOB46_002849"
     CDS             complement(1933..2193)
                     /locus_tag="NOB46_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059728.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          844 a          465 c          382 g          801 t
ORIGIN      
        1 tgtatgggct actctgtgat acttattagc cattaaacta ttttacccac atagcatata
       61 ttttgaaatc gttcattccg taaattcaac taaatatgcc taaaaaaata aaaaatctaa
      121 gatagaataa gatttattca gtcttagatg gatttatagc aactttttcg taacaacttt
      181 aaaaaatacg aaaagaaaga gctgttttac tctgactacg ttgctaaatt gtcgtttaat
      241 cattcattta aaccaaatct ttttttatag aattcgtttt aatcctcctg aatccaaaaa
      301 ctatgaaaac cgtaattaaa tagttaagag tttttaacca ccataattct ctcggctatt
      361 ttgaaatcag ataaattttg atcggacaca tagttgaata aacctaccgt tgttacggaa
      421 ggtaaatcgc atacttttca ttctagagga gaaggtctcg ttgatcatta actgattaag
      481 caccatagcc cagttttgaa ttcgaccacc tgaccacttc gcgtgtaatt ctttcgtgcg
      541 taaataaagt agttttagga gtgcattctc attagagaac gctccttttt ttgtgacttt
      601 tctgaagctg gagtggacac tttcaaccgc attggtagtg tacataattt ttcgaatggc
      661 actaccataa tcaaatagtt gttcaacatg tgcaaagttc cgtttccaga catctacagc
      721 accagaataa tgagaccacc gattttgaaa actgtcaaaa gcagcatgtg cagcgtttag
      781 agaagaagca ccgtagaact ttttcatatc tcggcagact tccttatagt ccttacttgg
      841 aatatagcgc aatgcatttc gaacaagatg aacaatacag cgctgaacaa ttaccgatgg
      901 aaagatcgct tttgcgcctt cttcgaggcc agaaacaccg tccatcgaaa tgaaaaagac
      961 atcttcgaca ccacgtgctt tcagttcatc aaatacttgc atccagcgat ttttagattc
     1021 tgtttgattt aaccataatc ctaaaatctc cttatttcct ttgagatcat agccaagaat
     1081 ggtgtataca gcatattctt tggcttcata attttctcgt aaagtaacat acatacaatc
     1141 aacgaataga aaggcataac actttgctag ggggcgggct tgccattctt ccaattcagg
     1201 aaggacagcg tcagtgatat ctgaaatcat ttcatgggaa atatcaaagc cataaatagc
     1261 ttcgacggtt gcggcaatat ctcgttgact cattcctcgt gcatacatgg aaagaacctt
     1321 cccttcgatg tcggagacat ctcgttttct cttaggaatt aactctggtt caaaggaagc
     1381 ttcccggtct ctaggaacat caatagctac ttcaccaaaa ctggttttaa gcgttttagt
     1441 tccatagcca tttcgacggt tatcgtgttc cttaggctct ttagaatggg catcataacc
     1501 taaatgatta ttcaattctc cttgaagcat tttttcaaaa aggggcccaa acacatcttt
     1561 caaagcatct tgcatgtcat cgacagattc aggttgatag gcattcagaa tggattcagc
     1621 taacttttcg gcatcaggat ttcttttctt tctagccatc gtgtaatcac ctcttgatct
     1681 tattgtagaa aaagaaaaac cgcgaagcaa ccacctgcct aggattaatg gttacttaca
     1741 cggtttatat tacactctca tcattaaaaa agtatctttc gatattacta aacaatgaaa
     1801 ttatctattt gaaatttaaa tctgataata tattgagtgt tccaatgagg gctttgatcc
     1861 tattatccat atctttttca gttttaatat tgatacacat tataagaaaa agaaactttt
     1921 ggttaattta tttcatccca gtgcaaaata taaaaaagta aaatagacca taggcaatag
     1981 attaacaatt aatataatac aagcaaatat tctattcatt gtatttctgc tttcaaaaag
     2041 ttctaatatt gaaagtataa ttccacaaat gcctataata agtatgggaa taagattaga
     2101 aaataacacc ccgagccaat ctgtgaaaat tactatattt actaatatcc ctattaacat
     2161 acctatcata tttattaaat caattttttt cattagatat ttctccttta ttaaatctga
     2221 agtacttata ttaaaataat tctaaactat ttacctcaaa aagtgcaata aattatttct
     2281 gaacaataaa atgatagtca aaacaaaaaa atattgttaa tcgttcagag ccatccgaga
     2341 gtgtaaaata ttttgtgtaa atgaaaaaat ccatacaaaa aaggaaggcg cttctgtaga
     2401 ataaagttaa cgacaaccaa ttcacagaaa agaggacttc cctatgaatg attttactac
     2461 agaaattgtg caaactctag tcactaaagg cg
//
LOCUS       DAIGUC010000136         2486 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.143, whole genome shotgun sequence.
ACCESSION   DAIGUC010000136 DAIGUC010000000
VERSION     DAIGUC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.143"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(1016..1306)
                     /locus_tag="NOB46_002850"
     CDS             complement(1016..1306)
                     /locus_tag="NOB46_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059729.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1514..2206)
                     /locus_tag="NOB46_002851"
     CDS             complement(1514..2206)
                     /locus_tag="NOB46_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI1059730.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          735 a          459 c          349 g          943 t
ORIGIN      
        1 acatacttgc aaagtaatac tacaattcct aacataatcg tagaatttaa taatttccat
       61 agcataaagt gtttagaaaa gaacattaag aatagttcta taataattct tgaactccat
      121 gtcttataat gttctatcga agcacccaaa tagccaagtt catctaatct acttgcataa
      181 actacgtcat ccgctctcat agtcggcata tacatattaa agagtaaaaa gataccccaa
      241 atccctatta gtaacaagat cagttctttg ttattcgtta tttttctatt atgtttgttc
      301 atttttatac tccttcttat atttcctaat agagtataac atagctttaa gcattactta
      361 aagataactt aaaagttatc ttttaaatac ttaattgtta aataccttat ttgatgcaaa
      421 agaaatctac gatagtcaac aaaaaaattt tcattatatc cagaaaaatt tttcttagtt
      481 aaggacctat ggattgcagt aatgcagaat tcgtcgaata aactgccaaa gacatacaat
      541 catattgctt ttaaaattga cgaacaagat atagattcgt ttgtctcaaa aatccaaatg
      601 ttaggtttaa ctgtcgaacc aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac
      661 ttttacgact atgataatca cctcttcgag ttacataccg gtactctcca ggaacgttta
      721 aaatcctaca attccactac ctgagactag taatgactag tctcttttta tggcctctga
      781 tccccccatt gagcgaatac taatagggct tcgaattgat ctgttcaatc tttaagcaat
      841 atccctcaaa tgagtttgga aagtttagtg attcatcaca aatacttaaa tacatgtagt
      901 tatatataga ttgaggttct tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg
      961 catccatctt tccaaaacaa gcggctagga catttttgtc tcagccgctt gttttctagt
     1021 ttattctttc atcttgtcgg accttttttc ttgggtatag acttttctca tattctacca
     1081 caattttggg tttccctaac acatgatagg atctcacaac aaattgcttt ctattattat
     1141 aataacctgt aacgactaac ttcatccctt cgtctacttc agctaggaag ttcaaactat
     1201 gggaagcaat caaacaattg accccattta aactgaaacg gatcaacggt ctggcactaa
     1261 cttgcaaagt acggatctta tctactgttc catatttttt ctccataacc ttcacctcaa
     1321 taccattata cgaacataca ttccctttgt aaagaagaaa ctctgtttta tctttttgac
     1381 tttttgtcta ttacctttct taaaatcata ttggcacttc ctgcgaagat gaaggacatg
     1441 tactaaaaaa aagaggcagc agtatagatt actgttgctt ctttactaat ttaggtttac
     1501 ttgttaagaa agattattta cgcaaatgtt cttcaacaat ttgctgagat ttatcagctg
     1561 tatcttccac ttcatctttt gctttttcta acttttgaat atattgtttc aagcttgagt
     1621 tttcagcagt tgcttcgtct aatttctttt gtgtatctgt taactgagtt tctacatttg
     1681 ttttttcttg tgtcagtgtt gcgatttgtt gattcaaacc atttacagta ttttgtaatt
     1741 ctgaaagttt tgcttgtgct tcttgtagtc ttgctgtcca atctgcattc agatgattga
     1801 tttcatcatt tttttggttg atctcatcta gtttgacatt gatttcattt tgtttgcttt
     1861 gtagttgtgc atccttgctg actaattgac tttctaagtt ttgtttttct gctgccgatt
     1921 gatttttttg gttttctaat tcatttactt ttgtttggta ttcttggaca tctgcctttg
     1981 aatcttgcaa tgtctgttct ttttgtgcta gtcgagcggt aagatctgta atcgcttgct
     2041 ctttatctgt caatgtatga tcaagctgtg tcagattctc attgattgta tcaatatctg
     2101 tctctccacc ccacaaaata atttcatttg cgtaccgcgt gcctgtgtag ccaattagac
     2161 atagaaatgc aacgacaatc ccaccagtaa taaatttctt tttcatttgc atagctcctt
     2221 aatccaatac ttttacatgc taaaagtaag tgatctcaaa cacaatgtca agcgttttta
     2281 aattacatat gtaattttaa tataaatact atcaaatact catttaatcc tcctttttta
     2341 tctatttaaa aaatcttttt tatagagaaa aatgcaggtt aatactttct taaataaata
     2401 tttatggtga acaaaaacaa aaaagcaagt tttattaaac gtaacccttt tcatttcata
     2461 gattactgta tttattacaa aaaacg
//
LOCUS       DAIGUC010000137         2422 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.144, whole genome shotgun sequence.
ACCESSION   DAIGUC010000137 DAIGUC010000000
VERSION     DAIGUC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.144"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..290
                     /locus_tag="NOB46_002852"
     CDS             <1..290
                     /locus_tag="NOB46_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059731.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(803..876)
                     /locus_tag="NOB46_002853"
     tRNA            complement(803..876)
                     /locus_tag="NOB46_002853"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(840..842),aa:Ile,seq:cat)
     gene            complement(1065..2084)
                     /locus_tag="NOB46_002854"
     CDS             complement(1065..2084)
                     /locus_tag="NOB46_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI1059732.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(2095..2301)
                     /locus_tag="NOB46_002855"
     CDS             complement(2095..2301)
                     /locus_tag="NOB46_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI1059733.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          740 a          466 c          405 g          811 t
ORIGIN      
        1 atgagacaca attatggttt aaatttgacc cttcgaatag atttatcaaa gatttttata
       61 aagtatggaa ttcagaagtt ttctttttag caatcgaaga tagcttatta atcaatctct
      121 actattctaa taagaactat ttcaaaattc ctgctgcgaa aactagaatg aagaaggatg
      181 tatacttttt gtttgatatc gtgactgacg tgccggacgc acgtagcgat catcggcgtt
      241 atgactatat aaagtatact ttcgttgatc cagaaagata caaagattaa agtaggctac
      301 ctaaaaaggt agcccggaac gaattttatc accatacttg tgaaaggaga tattttttaa
      361 gttagtatta agattgtgta atatgatgat atctatattt tatagtatca gtgctataaa
      421 atcaaaaata agtcactaat taactaccac tccaattgta agcctttttt ctcacttttt
      481 ttcaaaaata tggtatgcct tttaatagct tcaaatataa aagagtttaa agcgtaacac
      541 acttatgggg aagtggcttg gggtgcgctt taaactcttc tttattatca tctcacaatt
      601 taacccaaat gtctttctat ttaaaaatca aagtaaaact tttcaaatat acagaaatat
      661 aactatgtga aacatccttt cattaatcca taaaaggata cataaaaaag ccactcattt
      721 gagtggcaat gaagaaaagc tttagcttgt ataatactct tcaaaaaatt ctaacacaga
      781 acgattcaaa tggctacgtt aatgtaccct gtaggactcg aacctacgac cggacggtta
      841 tgagccgtct gctctgacca actgagctaa gggtactggt tgttgccaca taaagccata
      901 aacaatcaac cagtagaatg tgtggcaaca aacctgttat cgcatagctt ggagtgtgac
      961 tattatgggt gatagtgaag atatgcgata acatcactat tttatcgaat gatttttata
     1021 gttgtcaata tagttatgta atgctcctca acgaggagct atttttatcg tttaggaata
     1081 tttaaatacc aacgtttgtc atggaaatct tgcgcaccgc ctttagtgtt tccctctgga
     1141 tcattcgttg cccgcatcat gacatagact ttcttattag ggaagttacg catgttaaaa
     1201 gatacatgat agccaacatt tccagaagta ttataagctt gatttacatc tgatctataa
     1261 attccatcag ctcttactcg agctaattct ttcccagtat tgtaatccat aatgaagata
     1321 tactcgtatt tatagttagc aatgtgccat ccagctacat gcaaatttgc attttcgatt
     1381 tctccaaact gatcaatgtg ggcgtaattc gttccatctg tcagtgtagg attagctgca
     1441 ccagctcgtg ttggatcaat gacaggcttg ttttcagaag ttgttggatt ttcatcggta
     1501 aatccatgag ctaaatcata tgctaatttt tctttactta cgcccatttc agaaagataa
     1561 ccgtaaggat ctgtatgatc gccccagatg ttttgtgtta cccataaatg cgatttgatt
     1621 cccggttggt tataaggagt gtccaacgtt aatggaatac catatttcat tgctgaatct
     1681 ctagccaatt caacgtatgc cttgtagttt ttctcaaacg ttgctttatc atgtgtgtgt
     1741 tgtaactcaa tctgcacagg actgttggca ttagcatacg aaccagcacc gtactgtaca
     1801 taaccaggtt gaccgacttg ataaacaatt ccgccgtctc ccacaatata agcagtataa
     1861 gcgctagtcc atgaacgttg catatactgc gcttcattgc gtcctgttgc tgtttcatta
     1921 gccgtttcat gcagtaaaat atactgatta tttgctactt gtgagctacc ttcatttgcg
     1981 cccaaattaa attcattgtt gatagtatag gcaaatccgt taattggcaa taaaaaaaga
     2041 gccgttaaca ggctcatcgc agtaatagta attttctttt tcatatctat cctcctattt
     2101 atctgatgaa attttcttat acgttcgatt tgatacacct aaaatactcc ctagaaatgc
     2161 tccaaaacct gtaataatca tcaccgttat atctgtgtac cgccagttaa caccttttcc
     2221 gacaagaccg acaaaagtcg ctaaagcggg gataactact atagcgatcc atttcaaaat
     2281 atcaaaggtt ctattgttca tactatccac ctcccttcat tggttgggct actttctttt
     2341 tcaatcgctt gttttcttct atcaatattt ctctttctga aagcaaggca tcaatttgcc
     2401 cgtccagttg ttcaatttta tc
//
LOCUS       DAIGUC010000138         2403 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.145, whole genome shotgun sequence.
ACCESSION   DAIGUC010000138 DAIGUC010000000
VERSION     DAIGUC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.145"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            209..2071
                     /locus_tag="NOB46_002856"
     CDS             209..2071
                     /locus_tag="NOB46_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1059734.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2071..2403
                     /locus_tag="NOB46_002857"
     CDS             2071..2403
                     /locus_tag="NOB46_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI1059735.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          868 a          353 c          466 g          716 t
ORIGIN      
        1 taaaaaattt gaaaaagcgt ttgattattt atattacgac ttagtgcaat aaaaaacgct
       61 ttttaacagt acatgtagtc gtctttataa tagataaact ctgtaatatt agttaaaaag
      121 ctataagttg cacttagtta agtgcaaaca tttcatattg tcgttagttt agaaaacgct
      181 tatattagca atgtaaggag agatgataat gcagcagcta acaaaaagag aaaggcagct
      241 tttgatttac ttggtggaaa tgtctgaacc ggtaacaatc aaaaagttgg ctgaaaaaga
      301 aaatgttagt gttcggacga taaaatacga tctagatgat ataagagagt ggctgaatga
      361 gcggaagcaa gtcctatata gcaaacgtag tcagggaatt tggatgaata ttagtagctc
      421 tgatcgaatc aaattaaaaa gcgaattgat ggatgttaat cgttttgaaa tatttgcaga
      481 tcaaagtctc cgaatcaaac gtttactaat tatgctttta gtaacaaaag aagctattac
      541 tggaatgaaa atggccaacg cattagatgt cagcaaagat acgatcatga atgatttaga
      601 tgtgctggaa aataattttc ttaaggaagg attgaccttg aatcgtcagg cgcgaaaggg
      661 tttttggatc ataggagaag aacgtctagt tcgattaacg attgaagaga ttcttcaaaa
      721 agagttcacg gattatgaca tttataaatt aatgtcattg ttattgaatg gcggtgagac
      781 tgaatacttt gaaatgtatt ctgctactgc tacacctatc caagaggtat ttaatcaagt
      841 aatcattcga atgcgacact tactggaatt tgaaaatcta gagaaactga attacgcgga
      901 attactaaat attctgattc gagtgacaat tgctaccgtt cgcttacgca aagaggctac
      961 gattggtcgt tatcaattgg ttgctgaaca agaattagac aaaaacgatc tttcttatcg
     1021 cgtcatgcag caggtctttg attattatca gttgccactg ttcgaggatg aatatcatta
     1081 tatctatagt gatacattcg acacgattca ccagcaagac gtcatgaaac tagttgagaa
     1141 tgtgatttat aaagtaagta aagcaatcaa ccattctttt tatcaagatc cacaattgtt
     1201 gacgaatctg tatgctcatt tatccatgcg attatcgaga aagaaaaaat ttgtcaatga
     1261 atataatcct tttaaagaag atatcaagca gaaatacccg gaattatttg atgcgatcaa
     1321 gcaagcagtt cgacaagaaa taagtgaaca aaatattctg atcaatgatt ctttcgtggc
     1381 atatattgcc ttacactttt tggtttccta cgaaagagaa gaagatctac gaagcgttag
     1441 agccgtctac atttgttcaa cagggttggg tgtgactagt ctgatcaagc aaaagatcaa
     1501 tgaagaatta aataatatca ctatcgtggc atttgcttca gtattgaatg cgcaagaaat
     1561 gattgctacc aaagatcctg atttggtgat tagtattttt ccaattaatg gcatcgatcg
     1621 tcctttcatc aaagtccatc cattacccac tgaacaggac ttgaaaaaaa ttcaacaaat
     1681 aataaaaaaa atacttgctt cttccaatca gcaggaaagg cataacttga atcttagaga
     1741 aacgtccatc aataaagata ctttagaaga ctttagcaag gaattgattt tgaaagctta
     1801 tacgatttat gaacgtttac ttgtcatttt ggaagcagaa ttgatccaag aatatcgaga
     1861 agcttttttg cttcatgtat tcttaatggt tcatcgtatc acatttgatc aacaatatat
     1921 ggcagaaggt cgtcaagtag accagattat tttagacaaa ggaacactgg taggaaaaat
     1981 cgaagcagtt tttgcagaaa ataatttagg aatcaatcag tcagaaatca gtgcattatt
     2041 ctcatatata aaagaaggag cgtcaagtta gtgaaaatgt cagacgaggc tttaaaaatt
     2101 atcgaggaaa gtcaaaatcg ggaaaagtta aaacaagtga ttgatctaat tgaagagcga
     2161 ttagtagaac atgctattgt accaaccgag ttgcagtgga ccattctaat taatcacttg
     2221 aatgagatgc tgaaacgttc tcaaagaaag gaaacgattc ccgtagtcga tcgggatttg
     2281 ttcaaagaag tatccaaaga agccataact atttctgatg aaatagttag aagtatcggt
     2341 aatttaaccg atgatgaaat atatgttttg tcgattcatt ttgaaacagc aaaaaataat
     2401 taa
//
LOCUS       DAIGUC010000139         2293 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.146, whole genome shotgun sequence.
ACCESSION   DAIGUC010000139 DAIGUC010000000
VERSION     DAIGUC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.146"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(51..1598)
                     /locus_tag="NOB46_002858"
     CDS             complement(51..1598)
                     /locus_tag="NOB46_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HCI1059736.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="NOB46_002859"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="NOB46_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HCI1059737.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="NOB46_002860"
     CDS             complement(2043..2237)
                     /locus_tag="NOB46_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059738.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          644 a          477 c          408 g          764 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agt
//
LOCUS       DAIGUC010000140         2285 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.147, whole genome shotgun sequence.
ACCESSION   DAIGUC010000140 DAIGUC010000000
VERSION     DAIGUC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.147"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..1127
                     /locus_tag="NOB46_002861"
     CDS             <1..1127
                     /locus_tag="NOB46_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1059739.1"
                     /translation="SVRLYVRKDENGKQEYYVKKGFKTEKEAKLHEARKKVEIEDTGY
                     HKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFGNKSISKITPVHCQN
                     AVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPKREKKENENYFSLEE
                     LKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFEEQLMYVRKSYATIR
                     NEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQARELLQFGINTNTKN
                     QLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFRHTHATLLLEGGASI
                     KETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            complement(1216..1608)
                     /gene="rpsI"
                     /locus_tag="NOB46_002862"
     CDS             complement(1216..1608)
                     /gene="rpsI"
                     /locus_tag="NOB46_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI1059740.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(1624..2067)
                     /gene="rplM"
                     /locus_tag="NOB46_002863"
     CDS             complement(1624..2067)
                     /gene="rplM"
                     /locus_tag="NOB46_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCI1059741.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
BASE COUNT          749 a          418 c          417 g          701 t
ORIGIN      
        1 atagtgtccg cttgtatgtt cgtaaagatg aaaatggaaa gcaagaatac tatgtaaaaa
       61 aagggtttaa aactgaaaaa gaagccaagt tacacgaagc aagaaaaaag gtcgagattg
      121 aagataccgg ctatcataag ccttctaatg acttgtttat aacagtgtat gaagaatggt
      181 tgccttctta taggaatcgt gtacaagaaa cgacatatca acgtacaaaa gaccttttcc
      241 gcttgcatat actaccaaaa ttcgggaata agtccatttc taagattact cctgttcact
      301 gtcagaatgc agtcaatgaa tgggctttaa aattcaagaa tatcaaacag cttaagtctt
      361 acagctctca aatatttgag tatgccattt ttgcagagct attacaccga aatcctatgg
      421 caaatacaaa tctaccaaag cgggaaaaga aagaaaatga aaattacttt tcattagaag
      481 aactaaaagc tttttgggat attctcaata aagaagagcc tttaaaacat attttaatct
      541 tccagctttt gattactact ggtatacgta aaggagagct agctgctctt cattggtctg
      601 acatttattt tgaagaacag ctaatgtatg ttagaaagag ctatgcaact attcgaaatg
      661 aagagaagaa tgcaagaaga aaaactgtca ggattcaaaa aaatacaaaa aatatatctt
      721 ccgaacgaat attaccaatt gatgcacaaa ctattgaaat gttaaaaatc tggaaaaaag
      781 aacaagctcg agagcttttg cagtttggca taaatacaaa tacaaaaaat caacttatct
      841 ttacctatgt aaatgcagac ggtgacatta atcaaccttt gcatgcggac tattcaaata
      901 atatattgaa acgtttagag aagaaatata aatttaagca cgttactatt catggattcc
      961 ggcacactca cgctactctt ctactagaag gtggagcaag tatcaaagaa acacaagatc
     1021 gattgggtca taaaaatgct gaaactaccc ttaacactta ttctcatgtt actgaaaaag
     1081 ctcaacgaaa tgcgttagaa aaattcattg cttacactgg tttataatat tgtcattacc
     1141 tttctcatta ccagaacgaa aaaaagacac cttctcgcaa tgagaaagtg tctgaaatcg
     1201 ttggtataac aacgattaac gttttgaaaa ctgtgaagct ttacgtgctt tcttaagacc
     1261 tggtttttta cgttcgacca tacgtgcgtc acgagtaagt aagccagcac gtttaagagc
     1321 taaacggaag tcaggatcaa cttctagcaa tgcacgagcg ataccatgac ggatagctcc
     1381 tgattgtcca gcgtatcctc cgccgtttac gttaacaaat acgtcatatg cgccttttgt
     1441 ttcagtaaca gcgaaaggtt gattgattac ttcacgcaag tcagcatgtg gaatgtattc
     1501 ttcaacatct tttttattta cagtaatttt gccagttcct ggtactagac gtacgcgagc
     1561 aactgcgttt ttacgacggc ctgtgccgat atattgaact tgtgccaatg aaattccctc
     1621 ctattagatt aagtttgtga tgtctaaaac ttctggttgt tgtgctgcat gtggatgttc
     1681 tgctccaccg tatacgttca attttgtaaa ttgtttgcgg cctaaagtgt ttttaggaag
     1741 catacctttt acagaagttt cgatcaaacg acgagaattt ttagcacgca attcgccagc
     1801 agtgattgat ttcaatcctc ctgggtagtt gctgtgacgg taataaattt tgtcagtcgc
     1861 ttttttacct gttaatttca ctttgtctgc attgatgacg atgacgaaat cgccagtatc
     1921 caaatgaggt gtgaaagttg gtttattttt accacgtagt acagatgcaa caactgttga
     1981 aagacgtccc aatggaacat cagttgcgtc tactacatac catttacgtt ctacttcgcc
     2041 tggtttggcc atatatgttg tacgcacgtt attttcctcc aatttaagtt ctgatgtttg
     2101 acatacactt cgagtttccg gggctctttg tggggcaaac aataccattt aacatattac
     2161 ccgctaatct agtcaatgtc aacgtttttc tgcttgattg aaaaatttat atgaaacttt
     2221 acttcttttc tttcttttat ataaaagggt cgtttcctgt caaaatgaaa aacaaaaaga
     2281 ggctg
//
LOCUS       DAIGUC010000141         2138 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.149, whole genome shotgun sequence.
ACCESSION   DAIGUC010000141 DAIGUC010000000
VERSION     DAIGUC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.149"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..93
                     /locus_tag="NOB46_002864"
     CDS             <1..93
                     /locus_tag="NOB46_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI1059742.1"
                     /translation="RGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            72..359
                     /locus_tag="NOB46_002865"
     CDS             72..359
                     /locus_tag="NOB46_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCI1059743.1"
                     /translation="MIGNPSLNHRYRKGFYSLFKTLQQNQNTNSYQAAILTAVNLGGD
                     TDTTAAVTGALAGILYGGEVIPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            428..694
                     /locus_tag="NOB46_002866"
     CDS             428..694
                     /locus_tag="NOB46_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI1059744.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            684..953
                     /locus_tag="NOB46_002867"
     CDS             684..953
                     /locus_tag="NOB46_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1059745.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(1212..1478)
                     /locus_tag="NOB46_002868"
     CDS             complement(1212..1478)
                     /locus_tag="NOB46_002868"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059746.1"
                     /translation="MSRRSLEAHSISQLVGVRNGKNVAQNQKIQLREPGMGSYRFLIR
                     RSWSYASTDSFKSFWPFRVGKNGEVSRLGGGTQPTKVTATGEGT"
     gene            1660..2109
                     /locus_tag="NOB46_002869"
     CDS             1660..2109
                     /locus_tag="NOB46_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI1059747.1"
                     /translation="MYNEKKIVDIVTLKMVVAEKSLPIEKVRSSFEVGNWLIEEIGDY
                     AQEHPALLCLNTKNEITHFSIVHVGTLNQSVAHPRCIFQRAILANAARIMISHNHPSG
                     NTTPSENDIQFTNRLIKAGEVMGIELLDHIIVGQKKYLSLREEGYWN"
BASE COUNT          699 a          406 c          460 g          573 t
ORIGIN      
        1 cgaggattat ataagaaaac ccgaaaagaa ggcactctct tcgggttttc ggtctgtact
       61 gaaatcaagg tattattggg aatcccagct taaatcatag ataccgtaag ggattttatt
      121 ctttatttaa aactttgcaa cagaaccaaa atacgaatag ttatcaagca gccatattga
      181 ctgcggtcaa tttaggaggg gatactgata ctactgctgc cgtaactggt gctcttgcgg
      241 gtattcttta cgggggtgaa gtgatccctg aaaattggag aaaatcgctt caaaatgacc
      301 agcttcttaa aacgatcagt cagagatttt gcgataccgt gctatctcaa agaatttgaa
      361 taatggatat gatgcaaatc ttgtttgtac taacgttgta ttgacaaaaa ggattttatt
      421 tagtacaatg ttagtacaaa tgatgaacgg aggtagaatc atgtctcaat caaccattac
      481 atttaggatt cccgacgatg aaaaagaact ggtattagaa tatgcaaaag cacacaattc
      541 ttcattgacc gaactttatc gaaatgctgt actggataaa atcgaagatg aaatcgatct
      601 acggacttta cggagtgcaa ttgaagtttc caaagagaaa aaagagagtg gtatttctca
      661 agaggaaatg gagaaactgc taaatgaatt ataaagtcat ctacatgccg caagcccaga
      721 agcaattaaa aaaaatggac agaaaccaag ctaaaataat tgtcgcctgg atcagaaaga
      781 atttagaaaa cacgactgac ccgcgtcagc acggaaaagg tttgactgga aataagagtg
      841 gggaatggcg ctatcgaatt ggaaactatc gaatattggc taatatttgt gattctgaaa
      901 ttgaaatcca gatattctca attggacata gaagtacaat atataaaaga taaccgtttt
      961 tggaacgaag tagagtttcg aaagtcaatg tataatcttt tgaattttgc ataataccac
     1021 aggtagaaac tacccgatac tatcggttgg tttctgcttt tttatttggt cttgaagaag
     1081 aaaacgagtg atctgtggca aagaaagaaa caaaaaaagg acaaaactgt tgcttcgcct
     1141 gcggtgcagt cgcccctggc tcaaagcgca acagtttttt tggctagtgg caaggtctaa
     1201 ctgcttgttg gctacgtgcc ttcgccagtc gcagttacct ttgttggctg cgttcctccg
     1261 ccaagtcggc tgacctcacc atttttgcct acgcgaaaag gccaaaagga tttaaaggaa
     1321 tccgtcgaag catagctcca acttctccgg atcaaaaagc ggtaggaacc catgccgggt
     1381 tcccttagtt gaattttttg gttttgcgct acatttttac cattgcggac gccgactagc
     1441 tgcgaaatag aatgagcctc caggctacgc ctactcattc tacttctcgc aagtggcttc
     1501 gccaggcggc aagggcaagc aatgtgctac gcacccttgc cgcctgactg ctgcatggta
     1561 aaagcttcgc aacaaaacgc aaaaaattca gcctttggct accgctgtgt agcgcaaaga
     1621 ccaaaaggag aaggtcaaaa aatggaacca actacagtta tgtataacga aaagaaaatt
     1681 gttgatattg tcacactcaa aatggtagta gccgaaaaaa gtttgcctat tgaaaaagtg
     1741 agaagttcct ttgaggttgg aaattggttg attgaagaaa ttggtgacta tgcacaagaa
     1801 caccctgcgc tactttgtct gaatacgaaa aacgaaatta cccatttttc aatcgttcat
     1861 gtgggaacat tgaatcagtc agttgctcac ccacggtgca ttttccaacg tgctatattg
     1921 gcaaatgccg ctagaattat gatttcacat aatcaccctt caggaaacac aacacctagt
     1981 gaaaacgata ttcagtttac caatcgatta ataaaagccg gtgaagtgat gggcattgaa
     2041 ctacttgacc atattattgt cggtcaaaag aagtaccttt ccttacgtga ggaaggttat
     2101 tggaactaac gattaagact gcctgataat aaggcagt
//
LOCUS       DAIGUC010000142         2130 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.150, whole genome shotgun sequence.
ACCESSION   DAIGUC010000142 DAIGUC010000000
VERSION     DAIGUC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.150"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..74
                     /locus_tag="NOB46_002870"
     CDS             <1..74
                     /locus_tag="NOB46_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059748.1"
                     /translation="NQICEITNVSRASLYRKLSEVNN"
     gene            288..983
                     /gene="vanR"
                     /locus_tag="NOB46_002871"
     CDS             288..983
                     /gene="vanR"
                     /locus_tag="NOB46_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI1059749.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            961..2115
                     /locus_tag="NOB46_002872"
     CDS             961..2115
                     /locus_tag="NOB46_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI1059750.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          715 a          397 c          452 g          566 t
ORIGIN      
        1 taaatcaaat ttgtgaaatt actaatgtat ctagggcttc attatacagg aaattatcag
       61 aagtgaataa ttagccattc tgtattccgc taatgggcaa tatttttaaa gaagaaaagg
      121 aaactataaa atattaacag cctcctagcg atgccgaaaa gccctttgat aaaaaaagaa
      181 tcatcatctt aagaaattct tagtcattta ttatgtaaat gcttataaat tcggccctat
      241 aatctgataa attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa
      301 tacttattgt ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg
      361 agaattatac ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt
      421 ctgagattga ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct
      481 gtcaaaaaat aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag
      541 aggtagataa aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc
      601 gcccactgga gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg
      661 gagtaaagga gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca
      721 cccatgagtg ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac
      781 tgcgaatcct ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga
      841 tatggggcga cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt
      901 tgcgcgaaaa aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg
      961 ttggttataa aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac
     1021 atgtatatcg ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg
     1081 atccgaggga aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat
     1141 cacctggacg cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt
     1201 tatgtggcga ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca
     1261 aaatactttg acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa
     1321 attgagcttt ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact
     1381 ctggaaaagc gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg
     1441 tacttggcgc acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt
     1501 gacgaggctc cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac
     1561 aaagcgtatc gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta
     1621 caaacgataa cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc
     1681 gatgaatttt atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag
     1741 gatctgaccg tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa
     1801 aacgccgctg catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg
     1861 gatgtggtgt caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc
     1921 atatttgaaa agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga
     1981 cttggattgg cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa
     2041 agcaatgata actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat
     2101 aaaaggaggt cctaagagat gtatataatt
//
LOCUS       DAIGUC010000143         2074 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.151, whole genome shotgun sequence.
ACCESSION   DAIGUC010000143 DAIGUC010000000
VERSION     DAIGUC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.151"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            13..972
                     /locus_tag="NOB46_002873"
     CDS             13..972
                     /locus_tag="NOB46_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI1059751.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(1095..2069)
                     /gene="bsh"
                     /locus_tag="NOB46_002874"
     CDS             complement(1095..2069)
                     /gene="bsh"
                     /locus_tag="NOB46_002874"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI1059752.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          722 a          353 c          319 g          680 t
ORIGIN      
        1 gagtgagtac aaatgaccta tacccatctt acaacggatg aacttgtaat aatagagtct
       61 tatttcaaaa tgaatcaatc tgttgctaaa actgcccatt gcttgaatcg ttcaagacaa
      121 acgatccata aagtatatct gttcttcaag caaggaaaat cagccttaga atattatcaa
      181 cagtataaga aaaacaaatc aaactgtggt agacgtccgc ttgttttacc cgaggaacaa
      241 tcagaatata ttcaaagaaa ggttgttcaa ggatggacac ccgatgtgat tgttggtcgt
      301 gcagcgtttc ctattagttg ttctgctcgt accatttatc gtatgttcaa aaaggggcta
      361 tttgattctt ctgacttacc gatgaaaggc aagcgtaaac cgaatggaca tcaagaaaga
      421 cgtggaaaac aaactttccg ccgctctatt catgaacgtg aaaaggatta tagccaattc
      481 tcaaatgagt ttggtcacct tgaaggtgac actatcgtag gtctgaaaca taaaagtgct
      541 gtaattacct tagttgaacg attatcaaaa gttatcatca cattgaaacc gtgtggtaga
      601 caagcgattg atattgaaaa aaaattaaat caatggtttg aatctgtacc gaaaaaccta
      661 ttcaaatcca tcacttttga ttgtggaaag gaattttcaa attggaaaca gatcagtaat
      721 gtcaatgata ttgccattta tttcgctgat ccaggaacgc cgtctcaaag aggcctaaac
      781 gagaattcta acggattgtt acgtagagat ggtttattga aatctatgga tttcaattca
      841 gtagatgaat tttttattca atctgtcgca tctaaacgaa ataatattcc tagaaaatca
      901 ctggattatc gaacaccttt ggaagtattt ttgagttacg taagtattga tgatctgtct
      961 aacttaattt gacaattaag aagttaaaaa cattacaaaa aagacaagga tatcacatca
     1021 agaaaaaatg ttttgaaaat atctttgcct ttttgtatta tatctatatt aaataatcaa
     1081 tcacaacaca ttaactaatt tatatattta atttgttgtt tttctataat tggataacta
     1141 attaacttat gactatctaa gtcttcttta ttcatatcaa ttgcagtaat ttgactgtct
     1201 tcatatgttc gataataata gattcctttg tcaacattgc aacaagaaga ataaattgta
     1261 tattcatatt ttccatcacc aacatcacac aaaccttttt gttgttctac tgaacctaag
     1321 atatggaaaa attgactaat actttctgac tctgaatctc cagatacaga attcagcttc
     1381 gtaaaagtcg ctttaacaaa acgagatact gaggataaat ctccaggcaa gcctatccct
     1441 cccataccgc ggctataggc attcaaactt atttgatttg aaaaattatt tttaggagtt
     1501 tcactcgata agacacgata attgtttaaa ttaaataatt gatagtcaaa tgaaggatta
     1561 ttggtaagaa cgcccacagg gttatcatat atatgaagtc catctttcat actttcaatg
     1621 acaattgatt tttctttatc agctaatagc caatgtaaag gggataaagg aagttcatca
     1681 ctataattta tatttgctaa attgatattt tttaacaatt ttttagtttc tcctactgtt
     1741 gagcattgtc ctaaaatcca aggaataaat tcaaaaggag atacattgtc tttcccttct
     1801 tgtatttctt tataatcagc atacccagaa aaatttagcc cagccatact caatcctttt
     1861 tcatttgtcg catcgtaata aagagggtag tcagctatac cagcggcaat accaatcatt
     1921 gcataatgag tatccaaatc atttaccttt cgaaaattca acttataatt tcttggagta
     1981 acagtaacta cttcattgta agatatttca taatcaaaat tccttccaaa ataatgatca
     2041 cttgttacat aagtaataga cgtacacata gttt
//
LOCUS       DAIGUC010000144         2056 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.152, whole genome shotgun sequence.
ACCESSION   DAIGUC010000144 DAIGUC010000000
VERSION     DAIGUC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.152"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            493..714
                     /locus_tag="NOB46_002875"
     CDS             493..714
                     /locus_tag="NOB46_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059753.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="NOB46_002876"
     CDS             715..972
                     /locus_tag="NOB46_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059754.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="NOB46_002877"
     CDS             complement(1108..1710)
                     /locus_tag="NOB46_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI1059755.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="NOB46_002878"
     CDS             complement(1777..1932)
                     /locus_tag="NOB46_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI1059756.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAIGUC010000145         1994 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.153, whole genome shotgun sequence.
ACCESSION   DAIGUC010000145 DAIGUC010000000
VERSION     DAIGUC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.153"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            127..1851
                     /locus_tag="NOB46_002879"
     CDS             127..1851
                     /locus_tag="NOB46_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI1059757.1"
                     /translation="MKKKLLTLFLVMSFSIVLSVYYNTIVFSEQINYTEEQYNIEKEK
                     ALKVGYSEEQFKQIMEIPTNLSNENSETRIVNYTMTSNQTKVINKAMEQIGKPYEWGA
                     SGPNSFDCGGLVKYVYKQAVNIELPMGTTNQEQYGTEVSLNSLKPGDLLFYGNRGATY
                     HVGIYKGNGVMIHAPQPGETVKEVNIQYFYPNFAKRILPDEPDYPYIDYNKMVTVTKA
                     WSIWNDLQFSHEIKKAIIGDNYKIGKVYTNPENNNKYGEILVSNKVYGYINFYAVKEL
                     TSVQINRYLTSKDSGQPTWGNLECTISKGQTTKDKIYFVKGAYNLGDGKYLYSIYKDQ
                     DSSEWLGYLKAHVSLAYTPIEEINKNVTVTKNWSIWNNLQWEKEIEKPQIGSVFSARL
                     KLTNVSNNAVYYKLYKSGKFYGYINAEAVKDLTTTKLNKYVTFSVNNEDFWSSLDVNY
                     SKGKTERGRVFYISISYNTADNQPIYSVYTDETCTEWRGYYKGNNFEDTQITMLENKS
                     VKVTKSGYTVWGDLNFWTKSGISNTGDIYTTDRKFYNFTNNAYYYELKKDGRVYGYIN
                     SEAAVEMN"
BASE COUNT          783 a          241 c          348 g          622 t
ORIGIN      
        1 agtttgtaac aaacatatat tttttatatt acaatatttc aacaaattaa aaaaaattat
       61 atcttcttaa acaatgataa tattaaaatg caagcgcttg taaaaaataa ggagaagagg
      121 taaaaaatga agaaaaaact attaacttta tttcttgtga tgtctttctc aatcgttttg
      181 agtgtgtact acaatactat tgttttttca gaacaaataa actacacaga agaacagtat
      241 aatatagaaa aagaaaaagc tttaaaagtt ggttatagtg aagaacagtt taagcagatt
      301 atggaaatac ctacaaattt atcaaatgaa aatagtgaaa caagaatagt aaattatact
      361 atgacttcta atcaaaccaa agtcattaat aaagcaatgg agcaaattgg aaagccatac
      421 gaatggggag catcgggacc aaattctttt gactgtggtg gtttagtgaa atatgtttac
      481 aaacaagctg taaatattga actgcctatg ggaaccacca atcaagagca atacggtaca
      541 gaggtaagtt taaattcact taagcctggt gatttattat tttacggcaa tcgaggtgca
      601 acttatcatg taggtatata taaaggtaac ggtgtaatga ttcatgcacc gcaacctgga
      661 gaaactgtaa aagaggttaa catacaatat ttttatccta actttgcaaa aagaattttg
      721 cctgatgaac ctgactaccc ttatattgac tataataaaa tggtaactgt tacaaaagct
      781 tggtcaatat ggaatgattt acaatttagt catgaaatta agaaagctat tattggagat
      841 aattacaaga tagggaaggt ttatactaat ccagaaaata ataataaata tggagaaata
      901 ttagtaagta ataaagtata tggatacatt aatttttatg ctgttaaaga gttgacctct
      961 gttcaaataa acagatattt aacttctaaa gatagtggtc aaccaacttg gggaaatcta
     1021 gagtgtacta taagtaaagg acaaactaca aaagataaaa tatattttgt taaaggagca
     1081 tataatttag gggatggaaa gtatctatat tctatttata aagatcagga ttcctctgaa
     1141 tggttagggt atttaaaagc acatgttagt ttagcctata ctcctattga agaaattaat
     1201 aaaaacgtaa ctgttactaa aaattggtcg atttggaata atctacaatg ggaaaaggaa
     1261 attgaaaagc ctcagattgg ttctgtattt tcagctagat taaagttaac caatgtatcg
     1321 aataatgctg tctattacaa gctttataaa tctggaaaat tttatggtta tatcaatgct
     1381 gaggctgtca aagaccttac aacaacaaag cttaataagt atgttacatt tagtgttaat
     1441 aatgaagatt tttggtcttc tttagatgta aattattcaa aaggaaaaac tgaaagaggc
     1501 cgagtatttt acattagtat ttcatataat accgcagata accaaccgat ttattcagta
     1561 tatacagatg aaacatgtac ggaatggcga gggtattata agggaaacaa ctttgaagac
     1621 actcaaatta ctatgcttga gaataaaagc gtgaaagtaa caaaaagtgg gtatacagta
     1681 tggggagact tgaatttttg gactaagtca ggaatatcga acacaggaga tatatacacc
     1741 actgaccgaa aattttataa ttttaccaac aatgcttact attatgaatt gaaaaaagat
     1801 gggagggtct atggctatat aaatagtgaa gcagctgtag agatgaacta aaatattgct
     1861 gtcccttaat cttatggggc agcaatattt ttatattatt aatcattttt ctgaagcgag
     1921 ggtagaagaa ttaatcaata gtttttcttg ttttgtaata taatagttta attaccaaaa
     1981 attatttaag taaa
//
LOCUS       DAIGUC010000146         1979 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.154, whole genome shotgun sequence.
ACCESSION   DAIGUC010000146 DAIGUC010000000
VERSION     DAIGUC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.154"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(325..528)
                     /locus_tag="NOB46_002880"
     CDS             complement(325..528)
                     /locus_tag="NOB46_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059758.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSVKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(728..1744)
                     /locus_tag="NOB46_002881"
     CDS             complement(728..1744)
                     /locus_tag="NOB46_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI1059759.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          559 a          459 c          308 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat aatcgcttat
      661 cgtaaatcca cgtcactaaa cattgacgta aatttactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DAIGUC010000147         1858 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.155, whole genome shotgun sequence.
ACCESSION   DAIGUC010000147 DAIGUC010000000
VERSION     DAIGUC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.155"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..614)
                     /locus_tag="NOB46_002882"
     CDS             complement(<1..614)
                     /locus_tag="NOB46_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059760.1"
                     /translation="MTETKFIQDPWSKMTTRNGLRGDEAISALQKSIRRGKEKEACEF
                     AYEMYITSPQFEEKLWRRLLAISVEDVGMGNPMAAIMINNLNAMRKEFQYNESDRAMY
                     FFHAIRYLCQSEKDRSSDLLKNIVIKSFAMGYIPEIPDIALDKHTVRGQAMGRGSEHF
                     LHEASKVIPQAKVDNDYKEQYEKIIETYDPDHVVPSTFSFNPWQV"
     gene            655..1347
                     /locus_tag="NOB46_002883"
     CDS             655..1347
                     /locus_tag="NOB46_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI1059761.1"
                     /translation="MDVEMLIDKYQLNDSEAEVLRFMKKNRQSLKNIGIRDVAKASYV
                     STATIINMAKKIGYSGYSELVFALGNSQSDITMPSTFSNEEKEAFIHLMSAYRDKRIM
                     ILGSGFSQNLANYFSESLNLYGFRATANSHLEFLRQQVQQDILLFIISNSGDTVRLAE
                     LAKIANDHFIDVIAFVGQKNSKIGTLATLTISTETYIPQKISDYQPNLFFGTTLNQFE
                     LLLSAALKAIYK"
BASE COUNT          571 a          348 c          331 g          608 t
ORIGIN      
        1 acttgccaag gattaaatga aaacgtactt ggcacgacgt gatctggatc ataggtctcg
       61 atgatttttt cgtattgttc cttgtagtca ttatcaactt ttgcttgggg gatcacttta
      121 cttgcttcat gcaaaaagtg ttctgaacca cgccccattg cctgtccccg aacagtatgt
      181 ttatccaacg caatatcagg aatttctgga atatatccca tagcgaaact cttgataaca
      241 atgttcttaa gtaaatccga tgaacgatct ttttcagatt ggcataggta acgaatcgcg
      301 tggaaaaaat acatcgcacg atcggattca ttgtattgga attctttgcg catggcgttt
      361 aagttattga tcatgatggc ggccatagga ttgcccatgc ccacatcctc aacactgatc
      421 gccaatagcc ttctccagag tttctcttca aattgtggtg aggtgatata catttcataa
      481 gcaaattcac atgcttcttt ttcttttcct cgacgaatcg atttctgtaa tgctgagata
      541 gcttcatctc cacgtaagcc gttacgggta gtcatttttg accacggatc ttgaataaat
      601 ttcgtttctg tcataatata atactcctat tagataaaat ttgaggtgaa tcttatggat
      661 gttgaaatgc ttatagataa ataccaactg aatgactcag aagctgaagt cttacgattt
      721 atgaaaaaaa atcgtcagtc tttaaaaaat attgggattc gtgacgttgc caaagcatcg
      781 tatgtttcta ctgcaacgat tatcaatatg gcgaagaaaa ttggatattc cggttatagt
      841 gagttggtat ttgctctagg aaacagccaa tctgacatta cgatgccaag cacattctcc
      901 aatgaggaga aggaagcatt catacattta atgtctgcgt atcgcgataa acggattatg
      961 attcttggct caggtttttc gcaaaatcta gccaattatt tttcggaatc tcttaatcta
     1021 tatggatttc gtgcgacggc caatagtcat ttagaatttc ttagacagca agtgcaacaa
     1081 gatattctgc tttttattat ttccaattct ggtgatacag ttcgattagc cgaattagct
     1141 aaaattgcga acgatcactt tatcgatgtg atcgcatttg ttgggcaaaa aaattcaaaa
     1201 atcggtacgc tggcaacatt aaccattagc acggaaacct atattccaca aaaaatatct
     1261 gattaccaac caaatctttt ctttggcacg acactgaatc aatttgagct tttgttgagc
     1321 gcggcgctga aggctattta taaatagaag aacgctgtgg ccactgtttc ttcaaaatct
     1381 agtataaaga atcttcttta gaatgtaatt gttttctgtg tgttctgaac atgtttagga
     1441 atttccaaac ttgtttagaa aactttctca ttccctccgc tgtagaattg aactcacata
     1501 aaaaacatct aaaccaaaat atctacaagc ttggaaagga taataggttg ttattaaaaa
     1561 taatttttat tcctgaacct gaataattca tagctttaat tctttggcac attttattga
     1621 aatatgtatc actaatatcc ctatcaactg attttgacta aaaagttact tcaaacattc
     1681 actgttcaaa aatattgagg aataaatttt gggtgtaagg cattttgagc atacttctcc
     1741 ctggataact tcccagtaaa aaaatcgtta gattgttgga ttagatccat tgactgcctc
     1801 gcctcaggcg agcaaagacc ctgtagaatt cattctgata cacatgataa ctagataa
//
LOCUS       DAIGUC010000148         1795 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.156, whole genome shotgun sequence.
ACCESSION   DAIGUC010000148 DAIGUC010000000
VERSION     DAIGUC010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.156"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..447
                     /locus_tag="NOB46_002884"
     CDS             <1..447
                     /locus_tag="NOB46_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI1059762.1"
                     /translation="NLCVELNNEVSQSTDQTPDERWQTNEKEHLHPYQKNLLNPYFED
                     FIRRKVTKEEMVIFRKCRYSVAPRYIGKEVEIELSDKEDQVQIYYNGELIRSHPLTTK
                     QLNYHEEDYFQILKSDVMSHKEDDGIRAYTRESLKQYDLVEVADEE"
     gene            437..1177
                     /gene="istB"
                     /locus_tag="NOB46_002885"
     CDS             437..1177
                     /gene="istB"
                     /locus_tag="NOB46_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HCI1059763.1"
                     /translation="MKNSHYQELMTNLETLGLNHMREYVPNYIEVANREELSLTEALL
                     ELTRREVDHQNKQKMNRVVARARFSKRTSLEEFDFAFQPSINKREVLDLRHMGFVEKH
                     ENLVFIGSPGVGKTHLTIALGIEACRQGYRTLFITCHELLLRLRTAYEKGTLERVLKR
                     YARYDVLIIDEIGYLPIQKQEADLFFQLLAMRYEHRSTIITTNIVLSRWGELFQSSEI
                     AAAILDRLVHHVKVFKITGKSYRMRDKI"
     gene            1587..1751
                     /locus_tag="NOB46_002886"
                     /pseudo
     CDS             1587..1751
                     /locus_tag="NOB46_002886"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          579 a          369 c          351 g          496 t
ORIGIN      
        1 aacctttgtg ttgagttaaa taacgaggtt tctcaatcaa ctgatcaaac accagatgaa
       61 cgttggcaga cgaacgaaaa agagcacctg catccatacc aaaaaaacct tttgaatccc
      121 tattttgaag actttattcg ccgtaaagtc accaaggaag aaatggtcat tttccgtaaa
      181 tgcaggtact ctgtggcgcc tcgctatatc ggtaaagaag tcgaaatcga actctccgat
      241 aaagaagacc aagtacaaat ctattataac ggagaactga ttcggtcgca tccattaacg
      301 acaaaacagc tgaactacca cgaggaagac tatttccaaa tcttgaaatc cgatgtcatg
      361 agtcacaaag aagacgatgg aatcagagcg tatactcgtg aaagtctcaa gcaatatgat
      421 ctggtggagg ttgccgatga agaatagcca ttaccaagaa ctgatgacca acttagagac
      481 tcttggtttg aatcatatgc gggaatatgt tcctaactac atcgaagtgg ccaatcgaga
      541 ggagctttct ttaacggaag ctcttctcga gctgacacgc agagaagttg atcatcaaaa
      601 taagcaaaaa atgaatcgtg tggtggcacg cgcccgcttt tccaagagaa ccagcctgga
      661 agagtttgat tttgccttcc agccaagtat caataagcgc gaagtgctag acttaaggca
      721 catgggcttt gtggaaaaac atgagaactt ggtttttatc ggcagtcctg gtgtaggcaa
      781 gacacatctg acgattgcat tgggaatcga agcctgtcgt caaggctatc ggacactatt
      841 catcacctgt catgagctgc ttttgcgtct gcgaacagcc tatgaaaaag gtaccctaga
      901 gcgtgttctc aaacgatacg ctcgctatga cgtcttgatt attgatgaga ttggctatct
      961 tccgattcaa aaacaggaag ctgatttatt ctttcagctt cttgccatgc gctatgaaca
     1021 ccgctctacg atcattacga cgaacattgt cttatctcgt tggggggagt tgttccaaag
     1081 ttctgagatc gcagctgcca tccttgaccg tttagtacat cacgtcaagg tgttcaagat
     1141 cacaggcaag tcttatcgta tgagagacaa gatctaaagt gtcgattgtc gacaattact
     1201 attgccgaaa acctacattt ttatcctgcc caaaacctac aattttaagc tgcccttgac
     1261 atcaaaaaga cacttcacaa gctaagtgct atcgacaatt gaaacctttg tataaattac
     1321 ttctataatc agatgacgag ttggattata caacattcaa gaaatggcag aattttcaat
     1381 ggcgctattt aacagaaagt gaagtagttg attgtctacc ctcaatctct tatgaactta
     1441 aaatggctta gcagtattat caaaagctgc ttaacaatta tcacaagaaa cagctagcta
     1501 cttcgagaaa tgaccaaaga agttccctcg aaacttcact atcttaaaaa gcctttttca
     1561 tatctgaaaa aggcttttaa ctagcatttt cgaaaaagta ttttaataca aaattagaga
     1621 atcttcgcac acatatcaaa acattgaaac gatttgctta tggattttgc agttttacca
     1681 atatgcgctt gtggattttt ctaatcaacg ggttaataag ctatgcatta aaagctagta
     1741 aatcttacta actttgttga tcataaatga ccttatcagc ccgatttgac aaaga
//
LOCUS       DAIGUC010000149         1747 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.157, whole genome shotgun sequence.
ACCESSION   DAIGUC010000149 DAIGUC010000000
VERSION     DAIGUC010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.157"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(401..1612)
                     /locus_tag="NOB46_002887"
     CDS             complement(401..1612)
                     /locus_tag="NOB46_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003672456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI1059764.1"
                     /translation="MSFAVARMQKVKSGNLVGVGNHNQRNTDNHSNKDIDVERSHLNY
                     DLVNRTENYKRDIEQFINDNKSSSRAVRKDAVLINEWIITSDNPFFKDKDDKEIKDFF
                     DTAKSYFADKFGDNNIRYAQVHLDETTPHMHLGIVPFNDEHKLSAKTVFNRQALQAVQ
                     DELPKYLNERGFELERGEKGSERKNLTVPEYKKAKDELKEITTTLEQRKSEVLALSND
                     KAPTIKKESLDLKDETKTVKVPSGETIGIGKLRHEFMKNEERKTGNVIIPESKLNAVI
                     KSYEELYKANEKLKNYAETDLPKEITRVKEKYRELAKDYNRLVRKSNQNIETLEELEK
                     ENKSLKNEIKGIYKGFNQFMENTLGATVGQAKKLMNNLMSEVKEFVKGGEFEKIHRNE
                     TKTRDRDELSR"
BASE COUNT          457 a          383 c          255 g          652 t
ORIGIN      
        1 tttaatcttt ttatctattt ggacaatgga caatggacac atggggggtg tcgtagtgcc
       61 cccatgtttt ttcgctccaa aaattcccat gttttttcgc cccctgctcc cactaaattt
      121 ccaaataata aaaccgtggg ctattcgccc acacccaaca agcgcaaagc gcttgacctt
      181 gcctctgaaa agcaacttga taactgcatt cgtttctttc cgtcgtctta gcaaaagcta
      241 aacaactcaa aaaaagagat caagggtaaa tacactcact acgttcgccc ttgacctctt
      301 ttatttcgct gttttttacg catttgccga cgaaaagtaa acaatatgca gaattaccct
      361 agttttgata aaaaagcgct tagaacgcaa atatgagctt ctaacgactt aattcatccc
      421 tatctcgtgt tttagtttcg tttctatgaa ttttttcaaa ctctccacct tttacaaact
      481 ctttaacttc gctcataagg ttattcatca gctttttagc ttgtccaaca gttgcaccaa
      541 gggtattttc cataaactgg ttaaaacctt tgtaaatgcc cttaatttcg tttttaagcg
      601 acttattctc tttctctaat tcttcaagtg tttcaatatt ctgattactc ttacgtacca
      661 acctattgta atctttcgct aattcgcgat atttctcttt aactctagtg atttctttag
      721 gtaaatcagt ttccgcataa ttttttagct tttcatttgc tttatatagc tcttcatagc
      781 ttttaatcac tgcatttaat ttactttcag ggataattac atttcccgtt tttcgttctt
      841 catttttcat aaattcatgt cgcagcttac caatcccaat ggtttcgcca cttggtactt
      901 tgaccgtttt cgtttcgtct tttaaatcta aactttcttt cttgattgtt ggtgctttat
      961 cgttcgataa cgctaaaact tctgactttc gctgttccag cgtggtagtt atctctttta
     1021 attcgtcctt tgccttttta tattcaggca ccgttaaatt tttacgctct gacccttttt
     1081 cgccacgttc aagctcaaaa ccacgctcat ttaaatactt tggcaattcg tcttgtaccg
     1141 cttgtaaggc ttgacgatta aaaacagtct ttgctgatag cttgtgttcg tcattaaacg
     1201 gcacaattcc taagtgcata tgcggtgtcg tttcgtctaa gtgaacttga gcgtagcgga
     1261 tattattatc gccaaatttg tccgcaaaat atgatttcgc agtatcaaaa aaatctttaa
     1321 tttctttatc gtctttatct ttaaaaaatg ggttgtcaga agttatgatc cattcgttta
     1381 ttaatacagc atcttttctg acagcacgac tacttgattt attgtcgtta ataaattgct
     1441 caatatctcg tttataattt tctgtccgat tgaccaaatc ataatttaaa tgcgaccgtt
     1501 caacatcaat atctttgttg gaatgattgt ctgtatttct ctgattatga ttacctaccc
     1561 cgactaaatt tcctgatttt accttctgca ttctcgccac tgcaaatgac atgtaaacac
     1621 tcctaacttc ggcacaactt ccatgtaaag tataacccac tagacttatt tactacgttt
     1681 cataagtcat taatgcgtgt gctctgcgag gctagttttt gtgcaagcac aaaaaatgga
     1741 ctgaata
//
LOCUS       DAIGUC010000150         1491 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.160, whole genome shotgun sequence.
ACCESSION   DAIGUC010000150 DAIGUC010000000
VERSION     DAIGUC010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.160"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(75..159)
                     /locus_tag="NOB46_002888"
     tRNA            complement(75..159)
                     /locus_tag="NOB46_002888"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(123..125),aa:Leu,seq:caa)
     gene            complement(177..248)
                     /locus_tag="NOB46_002889"
     tRNA            complement(177..248)
                     /locus_tag="NOB46_002889"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(214..216),aa:Gln,seq:ttg)
     gene            complement(258..330)
                     /locus_tag="NOB46_002890"
     tRNA            complement(258..330)
                     /locus_tag="NOB46_002890"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(295..297),aa:His,seq:gtg)
     gene            complement(392..476)
                     /locus_tag="NOB46_002891"
     tRNA            complement(392..476)
                     /locus_tag="NOB46_002891"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(440..442),aa:Leu,seq:caa)
     gene            complement(497..567)
                     /locus_tag="NOB46_002892"
     tRNA            complement(497..567)
                     /locus_tag="NOB46_002892"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(533..535),aa:Cys,seq:gca)
     gene            complement(613..684)
                     /locus_tag="NOB46_002893"
     tRNA            complement(613..684)
                     /locus_tag="NOB46_002893"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(650..652),aa:Gln,seq:ttg)
     gene            complement(696..768)
                     /locus_tag="NOB46_002894"
     tRNA            complement(696..768)
                     /locus_tag="NOB46_002894"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(733..735),aa:His,seq:gtg)
     gene            complement(771..844)
                     /locus_tag="NOB46_002895"
     tRNA            complement(771..844)
                     /locus_tag="NOB46_002895"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(810..812),aa:Trp,seq:cca)
     gene            complement(851..931)
                     /locus_tag="NOB46_002896"
     tRNA            complement(851..931)
                     /locus_tag="NOB46_002896"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(895..897),aa:Tyr,seq:gta)
     gene            complement(933..1008)
                     /locus_tag="NOB46_002897"
     tRNA            complement(933..1008)
                     /locus_tag="NOB46_002897"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(973..975),aa:Phe,seq:gaa)
     gene            complement(1044..1116)
                     /locus_tag="NOB46_002898"
     tRNA            complement(1044..1116)
                     /locus_tag="NOB46_002898"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1081..1083),aa:Asp,seq:gtc)
     gene            complement(1126..1198)
                     /locus_tag="NOB46_002899"
     tRNA            complement(1126..1198)
                     /locus_tag="NOB46_002899"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1163..1165),aa:Val,seq:tac)
     gene            complement(1214..1285)
                     /locus_tag="NOB46_002900"
     tRNA            complement(1214..1285)
                     /locus_tag="NOB46_002900"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1250..1252),aa:Glu,seq:ttc)
     gene            complement(1300..1389)
                     /locus_tag="NOB46_002901"
     tRNA            complement(1300..1389)
                     /locus_tag="NOB46_002901"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1353..1355),aa:Ser,seq:gga)
BASE COUNT          433 a          386 c          337 g          335 t
ORIGIN      
        1 gatttggagg taattacata aaaacaaaaa aaatatagca actctctata agaaagttgc
       61 tatattgata attataccgg cggccggggt cgaaccggca cgtcctcaac ggacactgga
      121 ttttgagtcc agcgcgtctg ccaattccgc cacgccggca aatttaaaaa taataactgg
      181 ggtagctgga ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta ccgcttggct
      241 ataccccaag aataaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat
      301 ccggtgcgtt aaccacttcg ccacattcgc catcataaaa gatgttattt aatttctcaa
      361 taaaaaacta agatgaagac atcttagtca ataccggcgg ccggggtcga accggcacgc
      421 cctcaacggg cactggattt tgagtccagc gcgtctgcca attccgccac gccggcaagt
      481 tgatttatta gtactaaggc ggtaaccgga tttgaaccgg tgatgaaggt tttgcagacc
      541 tctgccttac cacttggcta taccgccatt atactattat caatctataa aataaagaat
      601 aaattataga aactggggta gctggattcg aaccaacgca tgagggagtc aaagtccctt
      661 gccttaccgc ttggctatac cccaagaata aaaagggcga atgatgggaa tcgaacccac
      721 gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc acattcgcca tggcaggggc
      781 agcaggaatt gaacccacac taacggtttt ggagaccgct gttctacctt taaactatgc
      841 ccctataaaa tggaggagag tggattcgaa ccactgaacc ctaaggaacg gatttacagt
      901 ccgtcgcgtt tagccacttc gctactcctc catggtggcg cgggacagaa tcgaactgcc
      961 gacacacgga gcttcaatcc gttgctctac caactgagct accgcgccat attttaaaat
     1021 tattaattga ataacaagaa cgacggttcc gacgggaatc gaacccgcga tctcctgcgt
     1081 gacaggcagg catgttaacc cctacaccac ggaaccagtt cattatggag gttaacggga
     1141 tcgaaccgct gaccctctgc ttgtaaggca gatgctctcc cagctgagct aaacctccaa
     1201 cattcaatta aaatgacccg tacgggattc gaacccgtgt taccgccgtg aaagggcggt
     1261 gtcttaaccg cttgaccaac gggccaggta aatttgctac ggagagtaag ggattcgaac
     1321 ccttgagaca gtttggcacc atctacatga tttccaatca tgctccttcg gcctctcgga
     1381 caactctcca gagtgaaaga agctcaatac tctttctcaa aatgagaact ccggcagtag
     1441 gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg a
//
LOCUS       DAIGUC010000151         1424 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.161, whole genome shotgun sequence.
ACCESSION   DAIGUC010000151 DAIGUC010000000
VERSION     DAIGUC010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.161"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..164)
                     /locus_tag="NOB46_002902"
     CDS             complement(<1..164)
                     /locus_tag="NOB46_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1059765.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTG"
     gene            319..567
                     /locus_tag="NOB46_002903"
     CDS             319..567
                     /locus_tag="NOB46_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005225422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI1059766.1"
                     /translation="MHWLWVLIVGAIIGLIAGAITNKGGSMGWIANIVAGLVGSAIGQ
                     ALLGSWGPQLAGMALIPSIIGAIIVVAVVSFFLGRSRG"
     gene            767..1171
                     /locus_tag="NOB46_002904"
     CDS             767..1171
                     /locus_tag="NOB46_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI1059767.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYRIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
BASE COUNT          453 a          236 c          316 g          419 t
ORIGIN      
        1 cccgtgttaa aaccaatgcg atcgtacttt tcgtaatcga ggaaagccgt taactccgtt
       61 ttgagaagcg tattgacagc tttttccaaa tggacacgga ataattcatt caaatcgcct
      121 ttgttcgcta gagtctttag aatttctgta gtaaaatcgt tcatatggaa gtcctctttt
      181 ctgtgaatgt gttgtggtaa ctctattcta cagaagggac ttcctttttt ctatttacac
      241 aaaatatttt acactctctt aagaagaagc gtaacataat atgtgtaata aatatttcac
      301 agaaagaaag agaaaattat gcattggtta tgggtattaa tcgtaggagc tattatcggt
      361 ttgattgccg gagcaattac aaataaaggt ggatcaatgg gatggatagc taacatcgtt
      421 gcaggtttag ttggttcagc aattggacaa gcattgttag gtagctgggg tcctcaatta
      481 gcaggaatgg ctttgattcc ttctatcatt ggtgcgatca tcgttgttgc tgtagtatca
      541 tttttcttgg gacgttcaag aggttaatcg tcaaatatat cagcaatttt acctattatc
      601 ttaaggagca gattttcgct gcttcttttt ttgtatagat aaactgcttc tatcactgat
      661 catcgatgtt gtctaactga tgtcgccgaa tgcaagcatt acctttgtca gattaaaaaa
      721 taatcgttac acttaatata gaacgacgaa agaaaggatg atctcaatga aaaaaatgta
      781 cgaaacagca atgatcaatc gtggaggccg tgatggcgag gttgaggcac caaacggaag
      841 tatgcacatg aagatcgacc gcccaggaat ccatagtgaa gggacaaatc cggaacaact
      901 ttttgcggct ggatacgcat cttgcttcaa cggcgcggtt caacacatgc tggaagaaaa
      961 taatcttgag tctgattctg aagtcaaagc acgggtatct ttatttcaat tagaagatgg
     1021 gggctaccga atcggggttg ttttagaagt ttctttgcca ggacttgaga aggaccaagc
     1081 agagaaaatc gcagaagaag cccacgcatt ttgcccatac tctaaagcaa caagaggcaa
     1141 tattgatgtg gaagtgacta tagtagaata agggattctt aatgttacta taaatgagat
     1201 tatgaaagat cctataaaga aacgctagta aaagaaacgc tagtaaaaga aacatgtagt
     1261 tacggtaatt aatagcggta tatgtacgat tgatcgaata gaacaaggag gcaaaaaaat
     1321 gacacagcgg gtagcaataa tgattttagt gttgctggtc attggcctcc ttgtttacta
     1381 tgtcctaaag tttaagcatt ggaagcagca acggatacat cagg
//
LOCUS       DAIGUC010000152         1424 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.162, whole genome shotgun sequence.
ACCESSION   DAIGUC010000152 DAIGUC010000000
VERSION     DAIGUC010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.162"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(150..1337)
                     /locus_tag="NOB46_002905"
     CDS             complement(150..1337)
                     /locus_tag="NOB46_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HCI1059768.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAIGUC010000153         1389 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.163, whole genome shotgun sequence.
ACCESSION   DAIGUC010000153 DAIGUC010000000
VERSION     DAIGUC010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.163"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            278..820
                     /locus_tag="NOB46_002906"
     CDS             278..820
                     /locus_tag="NOB46_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059769.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..1326
                     /locus_tag="NOB46_002907"
                     /pseudo
     CDS             976..1326
                     /locus_tag="NOB46_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414636.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
BASE COUNT          551 a          164 c          265 g          409 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccagatggaa tggcaacact ttttttgaca aaaattataa ggtgttgtga atgctgcggt
     1381 gttatggct
//
LOCUS       DAIGUC010000154         1364 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.164, whole genome shotgun sequence.
ACCESSION   DAIGUC010000154 DAIGUC010000000
VERSION     DAIGUC010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.164"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            82..>1364
                     /locus_tag="NOB46_002908"
     CDS             82..>1364
                     /locus_tag="NOB46_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HCI1059770.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAIGUC010000155         1338 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.165, whole genome shotgun sequence.
ACCESSION   DAIGUC010000155 DAIGUC010000000
VERSION     DAIGUC010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.165"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            72..>1338
                     /locus_tag="NOB46_002909"
     CDS             72..>1338
                     /locus_tag="NOB46_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HCI1059771.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIF"
BASE COUNT          453 a          253 c          256 g          376 t
ORIGIN      
        1 ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca actgagagga
       61 cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag aaagatttga
      121 tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc gtcgatgctg
      181 ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta gatggaaacg
      241 ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt gaacaataca
      301 atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa aactgtcgaa
      361 cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg aatcatgtca
      421 gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt gcgaaaaatt
      481 gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc tacttaccaa
      541 agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt tcgcacgctt
      601 ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa ttaattgatg
      661 tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc gctaatcctg
      721 aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt accaaacgta
      781 ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac atgaatcaag
      841 cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga cagaaaagtc
      901 aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca aacatcaacc
      961 attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt cttacggaag
     1021 cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg tatccctatt
     1081 ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc tccttattgg
     1141 cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac cttctgacct
     1201 atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa atagaagcga
     1261 agaataccca tataaagaca atgaaacgag tatcctacgg atttaaatca tttgagaaca
     1321 tgagaattag aatctttt
//
LOCUS       DAIGUC010000156         1323 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.166, whole genome shotgun sequence.
ACCESSION   DAIGUC010000156 DAIGUC010000000
VERSION     DAIGUC010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.166"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            746..1323
                     /locus_tag="NOB46_002910"
                     /pseudo
     CDS             746..1323
                     /locus_tag="NOB46_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738373.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          464 a          242 c          233 g          384 t
ORIGIN      
        1 cctcagttga acctaatgga aggcgtttgg aagtggctca aggaatcggt catcaacaat
       61 gttttttttg accacgtcca gaaaatcaaa cagtcggtcc gcggtttctt agccgatgta
      121 aacgagcgtc cccttgaggt gattgaccga ctgtgcgtgc ggatgtaaag tatttaattc
      181 aacctatata gcatacaata cctaggctac aaaaattttc tgacaatcag aaaagatgct
      241 atctatgatt gggatgaaac acagaaatta aaagtagtta atgtgattga ctactaagca
      301 tgaagaacca ttaaagcgat caaataataa ctaatgatga gcctagggag aaaagattcc
      361 ctaagctttt tcattaagta caaaaataaa taaccagtgt ttttgaaatt gaacttcaca
      421 caatagaaat accgtcttct aaagtataaa aaacgtttat aaagactatc cgcttattca
      481 ctcattttac agtacttttt ccaacctctt tctagacttc agccagctcc tccgctattc
      541 aagaactgat cgatattcca aagaaaaatt ccactatact tgactctaaa ataaaaaaaa
      601 tgaataaaat agtaaattag aatcattgaa aaatagtctg catcctttag acttaaattg
      661 taagcgaaaa cgtttacgac tatattatat taacaggagg aatatcatga aaaaaaaatc
      721 atcactggtc agtttattaa taggaatggt cgctttagcc atctttttaa tcccgaccaa
      781 agcagcacat gctgacgtca ctgtaacaaa cgattgtacg gacttttcaa gcatccaggc
      841 ttcaattaat gcgaattctt caggacaggg taacaccaat tacttcaata ttgaacctgg
      901 tcaatcagac tcttggagta gactttctcg tactgggttt atcttggcga ttgtccataa
      961 aggaatgcta agaacctatt atacgccaac gagtgcttct tactcttatt aagatggtaa
     1021 actttatcaa aaaaacaatt cagctgaaat cacaccattg aaagccgtag tattctctga
     1081 ggaaaaagct actaaaattg taaatatggt caatctctct gatggtacag ttcaggttgc
     1141 attaagcaaa tggaaaactg gcgggtatgc agattacttt gaactttctc gtccagccgt
     1201 tgagagctgg agcagaaaca atgatccaag aggcttttta gtttcattga gagctaaagg
     1261 cgaaatgaat gaatacatat attatttacc tagcattgaa aatatcggtg gaaattattt
     1321 aac
//
LOCUS       DAIGUC010000157         1188 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.169, whole genome shotgun sequence.
ACCESSION   DAIGUC010000157 DAIGUC010000000
VERSION     DAIGUC010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.169"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            141..398
                     /locus_tag="NOB46_002911"
     CDS             141..398
                     /locus_tag="NOB46_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059772.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="NOB46_002912"
     CDS             complement(630..1061)
                     /locus_tag="NOB46_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HCI1059773.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DAIGUC010000158         1093 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.170, whole genome shotgun sequence.
ACCESSION   DAIGUC010000158 DAIGUC010000000
VERSION     DAIGUC010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.170"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..1060
                     /locus_tag="NOB46_002913"
     CDS             <1..1060
                     /locus_tag="NOB46_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI1059774.1"
                     /translation="RTYLELKKQRFKCKACQRTFVADTSVAKKHCFISEKVRWSVVTR
                     LKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPKVLCFDEFKSVRGVSGAM
                     SFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWIVIDMYAPYVSLVKKLF
                     PKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLGKQLKRYWKLLQKDER
                     KLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFLYAVKERDYVSFEEL
                     LTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHIKVLKRNAYGFRSF
                     YNFKLRIMIRHGNALIFN"
BASE COUNT          343 a          228 c          206 g          316 t
ORIGIN      
        1 ccgtacctac ctcgaattga aaaagcaacg cttcaaatgc aaagcttgtc agcggacctt
       61 tgtcgcagat acttctgttg cgaaaaaaca ttgtttcatc agtgagaaag tccgctggtc
      121 tgtcgtgact cgtctgaaaa aaaatacctc aatgacagag atcgccgctc agaaaaatct
      181 atcggtctct tctgtttacc gtattatgaa gcgattttat cgtccgttga atccttttcg
      241 gacaccgtta cctaaggtac tttgttttga tgaattcaaa tcagttcggg gtgtttcagg
      301 tgctatgagt ttcatcatga tggatggaca aacacagcgc ttattggaca ttgtcgagaa
      361 ccgacaactg ccttttttaa aacgttattt tagtcatttt tcacgagaaa ttcgtgaagc
      421 ggtcgaatgg atcgtgattg atatgtacgc tccttatgta tcgctcgtta aaaagctgtt
      481 tccaaaagca cagctgatta ttgaccggtt tcacatcgtc caacatattg gtcgtacctt
      541 tcgcaatcat cgaatcaaag aaacgaacca actattaaaa agcaaagaac aaaaacacta
      601 tcaattaggt aagcaattaa aaagatactg gaaacttctt caaaaagatg aacgcaagct
      661 tgattatact cgacgccttt ggcgacctgg cttcaaagct catttaacag agaccgatat
      721 tgtggatcgc ttactgaaag ggagccctgc tttgcgtgta ggctatcagt tatatcaaga
      781 ctttctttac gctgtaaagg aacgagacta cgtatcgttt gaagaactac ttaccaataa
      841 tatcatgctt cccgaaggct atcagacgac cttgagaacg ttccagaaat ttctgccaca
      901 aatcaaaaat gctttacaac aaagttattc aaatggccca cttgaatgtc tgaacaacca
      961 tatcaaagtg ttaaaacgaa atgcatatgg ctttcgtagc ttttataatt tcaaattgcg
     1021 catcatgatt cgtcatggca acgcattgat tttcaactaa aaaagatcaa gaggaactga
     1081 tccacttgat ctc
//
LOCUS       DAIGUC010000159         1062 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.171, whole genome shotgun sequence.
ACCESSION   DAIGUC010000159 DAIGUC010000000
VERSION     DAIGUC010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.171"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(37..993)
                     /locus_tag="NOB46_002914"
     CDS             complement(37..993)
                     /locus_tag="NOB46_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059775.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DAIGUC010000160         1050 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.172, whole genome shotgun sequence.
ACCESSION   DAIGUC010000160 DAIGUC010000000
VERSION     DAIGUC010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.172"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            89..1024
                     /locus_tag="NOB46_002915"
     CDS             89..1024
                     /locus_tag="NOB46_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI1059776.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYTGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT          366 a          167 c          238 g          279 t
ORIGIN      
        1 gttataaaaa tgaacattgc atagtagaga ttctttgatt atactaattc aaggttatat
       61 gaaaaaagag aaatgagatg gatgatttat gaaactttgg atgaaaatcc ttttaggcgt
      121 cgctttagct ctgattgttg cgttagtgtt tgcagggaat tatttttata attatgctgt
      181 tgtgccttct gagaaagact ttttagacga agatacacct ggtacaacac agacatccaa
      241 agaaacggat gcacataaat ggtttagttc aaaagaaaac cgaagcgatt ggaccatcac
      301 ttcaaaagac ggtctgaaat tatcagcgat ttatcttcct gctgaaacga aaagtgaaaa
      361 aacagctctt gtggctcatg gctatatggg aaacgctgaa acgatgacca attacgcaaa
      421 gatgtttcat gatatgggtt acaatgtcct tgttcctgat gcaagaggac atggaaaaag
      481 cgaaggggat tacactggat ttggatggcc agagcgtaaa gactatgtac agtggataaa
      541 caaagtgcta gaaaacaatg gaaaatcgca agaaatcgtt ctatacggtg tcagcatggg
      601 agcagcaaca gttatgatga ctagcggaga aaaactacca gataatgtga aagcaatcat
      661 tgaagattgc ggttattctt ccgttcatga tgagcttgct tatcagctag acgatatgtt
      721 tagtcttcca gcatttccgc ttatgcaagt aacgagtcta gtgacaaaag tccgtgctgg
      781 ctactttttc ggtgaagcaa atgcagtgga acaattgaag aaaaaccagc gcccaatgct
      841 ctttatacat ggagacgaag atacatttgt accatttgaa atgttagata aggtctatcg
      901 tgcaacgaag ggaccaaaag aaaagtatgt tgtaaaagga gccgagcatg cggaagcata
      961 caagacagat cctgaaaaat atcagcaagt agtccaacaa tttttaagcc aatatgttca
     1021 ttgaacgagt ttaaaagtag gggatgaaaa
//
LOCUS       DAIGUC010000161         1035 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.173, whole genome shotgun sequence.
ACCESSION   DAIGUC010000161 DAIGUC010000000
VERSION     DAIGUC010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.173"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..>1035)
                     /locus_tag="NOB46_002916"
     rRNA            complement(<1..>1035)
                     /locus_tag="NOB46_002916"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAIGUC010000162          979 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.174, whole genome shotgun sequence.
ACCESSION   DAIGUC010000162 DAIGUC010000000
VERSION     DAIGUC010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.174"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            108..>979
                     /locus_tag="NOB46_002917"
     CDS             108..>979
                     /locus_tag="NOB46_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HCI1059777.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVT"
BASE COUNT          428 a          105 c          158 g          288 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaac
//
LOCUS       DAIGUC010000163          962 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.175, whole genome shotgun sequence.
ACCESSION   DAIGUC010000163 DAIGUC010000000
VERSION     DAIGUC010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.175"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..506
                     /locus_tag="NOB46_002918"
     CDS             <1..506
                     /locus_tag="NOB46_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059778.1"
                     /translation="LLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGR
                     KEICEDFKLVYQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRR
                     TIYSTNLIEGFNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQ
                     DTLESMI"
     gene            complement(846..>962)
                     /locus_tag="NOB46_002919"
     CDS             complement(846..>962)
                     /locus_tag="NOB46_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI1059779.1"
                     /translation="TIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          326 a          165 c          147 g          324 t
ORIGIN      
        1 ttttattagt agtgacagac ggattaagct gtattgaaga aagtatccat agtgtgtatc
       61 cgaatgccca atttcaacaa tgttgtgtgc atgtatctag aaatatcgct cataaagttc
      121 gtgttcgagg tcgaaaagaa atttgtgagg atttcaaatt ggtttaccaa gcgaattcaa
      181 aagaagaggc attggatcac atcgacttta tgactaggaa atggaaaaag cagtatccaa
      241 gagtcgtcaa tttactcttg aatcctgccc tattaacctt ttataatttc cctcacgcca
      301 tcagacgaac aatttattcg acgaacctga ttgaaggctt taataagcag ctaaaacgat
      361 atactcgaag aaaagaacaa ttccctaatg aagaatctct agagagattc ttcatttctc
      421 aatttaatca atataaccaa aaatttttag gtagaattca caagggattt aaagaaattc
      481 aggatacatt agagtcgatg atttaactgt aattaacaga atggattttc catttacata
      541 taattcttga cgctaccata atctaaataa ccatcatatt catctactac ttatataatt
      601 gagttttatt aaacttttta agtttctatt ctatcaaata tttaaacaat ctctgcatcc
      661 gaaaagacta cctcgtatag ttttactaac aatattttta ttagcgtgtt caaatcctga
      721 tttcttgtat caattatttt ctgttcactt tcaataagaa aaaagtcttt acttccatgg
      781 ataataataa gggttctgtt gcaaagtttt aaataaagaa taaaatccct tacggtatct
      841 atgatttaag ctgggattcc caataatacc ttgatttcag tacagaccga aaacccgaag
      901 agagtgcctt cttttcgggt tttcttatat aatcctcgga tggcttccat gcctttaatc
      961 gt
//
LOCUS       DAIGUC010000164          927 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.176, whole genome shotgun sequence.
ACCESSION   DAIGUC010000164 DAIGUC010000000
VERSION     DAIGUC010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.176"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            54..927
                     /locus_tag="NOB46_002920"
                     /pseudo
     CDS             54..927
                     /locus_tag="NOB46_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          362 a          153 c          177 g          235 t
ORIGIN      
        1 acagaaaaat taaggtgtgt agactagaag aaaacatacc aggaggaatt tttatgtcta
       61 agagaacacg aagaactttt tcacaagaat tcaagcaaca aatcgtcaat ctttacttag
      121 ctggaaagcc acgtgtagaa atcattcgag aatatgaact aacggcttca gcatttgaca
      181 aatgggtaaa gcaatctaaa acgagtggtt cattcaaaga aaaagataat cttacgcctg
      241 aacaaaaaga attgttagaa ctacgtaaaa gaaaccagca attagaaatg gaaaatgata
      301 ttttaaagca agcagcgctg atattcggac gaagagacaa gtaatcgatg cgaataagca
      361 tctttaccct atatcagcga tgtgcagaat attaggtcta tcacgtcagt cctattatta
      421 tcaatcaaaa ccaaagaaag acgaatcaga acttgaagaa gtagtcgctg aagaatttat
      481 ccgcagccga aaggcctacg gctcaagaaa aataaaaaaa gccttatcaa aacgaggcat
      541 tcagatcagc cgacgaaaaa ttagtagaat catgaaaaat agaggattaa aatcgagcta
      601 tactgttgct tattttaaag tacatcattc tacttgcaat gaagccaaaa cgacaaacgt
      661 attgaatcgt aaattcttaa gagacaaccc attagaagcg atcgtaacag acttgactta
      721 tgtacgagtc gggaaaaaat ggaattatgt ctgtttcatt ttggatctgt tcaatcgaga
      781 aattctcggc tattcttgtg gagaacataa agatgccgtt ctagtaaaaa aagcatttag
      841 ccgtatcaaa caacctctga cagaggttga gatttttcat actgatcgtg gaaaagagtt
      901 tgataaccaa gctattgatg aattatt
//
LOCUS       DAIGUC010000165          890 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.177, whole genome shotgun sequence.
ACCESSION   DAIGUC010000165 DAIGUC010000000
VERSION     DAIGUC010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.177"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            715..>890
                     /locus_tag="NOB46_002921"
     CDS             715..>890
                     /locus_tag="NOB46_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI1059780.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWG"
BASE COUNT          305 a          126 c          118 g          341 t
ORIGIN      
        1 aataattgta ttttctcttc ggtaaagttt gagttattaa ttttattgat tgaactggta
       61 aaaatgtcta caaaaatatt atttcgacta tcaatttttt gattttttta gtttggtact
      121 catagcccaa tcttttgaaa tgtaatagcg ctggtacttt tactctacta tcttcattat
      181 gtatcaagat aaaatctcct ttatataata tttccttcta taattacttt actttttaat
      241 cagcaatttg aagcaaacag attagtattt atcttaatgt gtaatacttt tcacgagtta
      301 caatctttat gtgaaatact gttggttttg aaggacttcg cctatttaag ttatttttaa
      361 cgaccaaaca gctaagattg cttgtagtta agtagcataa aacttccatt caattagatt
      421 cacacaaata attatatatt cttgatgatt ttagtttttc ttgtaaagaa tcaaaaatat
      481 gctttattag ttattttata accgattttt tcttttacaa tatataactc gaaatcgact
      541 actaattctc taaatcttca gttattgttt taatagtatt ttcggttgaa ataaagtata
      601 tatacccgtg gtgctagtta attttttcct agaggaaaat gtctaaacat gttggtaaat
      661 caacaaaaaa acgcatatag tagtctcaaa actcccaaga aatgaggact acatatgcgt
      721 tcatcaaaat atactgaaca ttatacagat acttttataa cattcaagga aattatgaga
      781 actgtttcta acatatacca caattgtgta ccagataaga ttaaaaaccg aagaaatact
      841 gatcaactga agcaacgcga tacagtgatt attgcttgtg ttatatgggg
//
LOCUS       DAIGUC010000166          870 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.178, whole genome shotgun sequence.
ACCESSION   DAIGUC010000166 DAIGUC010000000
VERSION     DAIGUC010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.178"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            123..>870
                     /locus_tag="NOB46_002922"
     CDS             123..>870
                     /locus_tag="NOB46_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HCI1059781.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDILEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVRTLNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRG
                     VHDVLLFITDGLKGMKDTIHQIYPKAKYQHC"
BASE COUNT          287 a          175 c          173 g          235 t
ORIGIN      
        1 ttttatataa taaaatgcaa tacttttcga gagtgtaaaa tattttgtgt aaatagaaaa
       61 aaggaagtcc cttctgtaga atagagttac cacaacacat tcacagaaaa gaggacttcc
      121 atatgaacga ttttactaca gaaattctaa agactctagc gaacaaaggc gatttgaatg
      181 aattattccg tgtccatttg gaaaaagctg tcaatacgct tctcaaaacg gagttaacgg
      241 ctttcctcga ttacgaaaag tacgatcgca ttggttttaa cacggggaat tctcgtaacg
      301 gctcctatga ccgtacggtc aagaccgagt acggggaact tcatctccag attccgcgcg
      361 accgcaacgg cgagttcaag caacagactg ttcctgctta tagacggacg aatgatatct
      421 tagaggagac cgtcattcac ctcttccgaa aaggtattac catgtcggaa atcgcagact
      481 tgattgagaa aatgtatggg catcactaca cgccccaaac catgtccaac atgactaaag
      541 tgctgactga agaagtaaat gcatttaaag ttagaactct aaatgataag tatgtcgcta
      601 ttttcatgga tgctacttat attcctttaa aacggcaaac cgtctccaaa gaagcaatct
      661 atattgccat tggtatacga gaagacggca ctaaagaagt actaagttat gcgattgctc
      721 cgactgaatc gacctacgtt tggaatgagt tgttacagga catttactcc agaggggttc
      781 atgatgtctt actgtttatt accgatggct taaaaggcat gaaagatacg attcaccaga
      841 tttatcctaa agctaaatac caacattgct
//
LOCUS       DAIGUC010000167          868 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.179, whole genome shotgun sequence.
ACCESSION   DAIGUC010000167 DAIGUC010000000
VERSION     DAIGUC010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.179"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            81..>868
                     /locus_tag="NOB46_002923"
     CDS             81..>868
                     /locus_tag="NOB46_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HCI1059782.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNI"
BASE COUNT          321 a          160 c          161 g          226 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatctt
//
LOCUS       DAIGUC010000168          867 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.180, whole genome shotgun sequence.
ACCESSION   DAIGUC010000168 DAIGUC010000000
VERSION     DAIGUC010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.180"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..210)
                     /locus_tag="NOB46_002924"
     CDS             complement(<1..210)
                     /locus_tag="NOB46_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI1059783.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="NOB46_002925"
     CDS             complement(309..623)
                     /locus_tag="NOB46_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059784.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..837)
                     /locus_tag="NOB46_002926"
     CDS             complement(691..837)
                     /locus_tag="NOB46_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059785.1"
                     /translation="MILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
BASE COUNT          285 a          172 c           90 g          320 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catcctt
//
LOCUS       DAIGUC010000169          856 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.181, whole genome shotgun sequence.
ACCESSION   DAIGUC010000169 DAIGUC010000000
VERSION     DAIGUC010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.181"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            661..>856
                     /locus_tag="NOB46_002927"
     rRNA            661..>856
                     /locus_tag="NOB46_002927"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          345 a          142 c          161 g          208 t
ORIGIN      
        1 gaattcctta ggcagctttt gctgtgtaga aaggaataaa taataacgaa agttcaaaag
       61 ctaatgccga ctattctaga cattaaagaa gacgaaaacg aacgataaag aaagaaaagt
      121 tatgaataat cgtttattga aaaaaacttg aaaaaataca aaaaattcgt tgaccaagct
      181 aaatttagtt ggtatattat tacttgtcca aaagacagaa gaaaatattt attcaaaaac
      241 ataacaaaaa agttattgac atgttactaa cgacatgata agataactga gtcgttaaaa
      301 aagaaccact tgcgaagctt gattctatcg aaaaaaactt caaaaaagtt cttgacaaat
      361 aacaaacgat aagttatgat aaatgagttg ccgaaagatt tcgaaaaacg aaatcgaaaa
      421 aaacttttaa aaaagagttg acaatcgctt gtctctctga tatgatataa aagttgctac
      481 ggcagccaaa aatgaatcgg gaaacactct cgatgaagta gacctttgaa aactgaacaa
      541 agtaagacaa accaaatgtg tagggcgtct tgattcaatt caagacaaca aacattttta
      601 acaagcaagc aatatgctag caaacaaatt gagcttaaca atcgcaagat tgttcgaact
      661 ttttatgaga gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa
      721 gtcgaacgct tctttttcca ccggagcttg ctccaccgga aaaagaagag tggcgaacgg
      781 gtgagtaaca cgtgggtaac ctgcccatca gaaggggata acacttggaa acaggtgcta
      841 ataccgtata acaatc
//
LOCUS       DAIGUC010000170          850 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.182, whole genome shotgun sequence.
ACCESSION   DAIGUC010000170 DAIGUC010000000
VERSION     DAIGUC010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.182"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(44..>850)
                     /locus_tag="NOB46_002928"
     CDS             complement(44..>850)
                     /locus_tag="NOB46_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HCI1059786.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIVTDL
                     TYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          227 a          202 c          159 g          262 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggtt tggttatcaa
      361 attcctttcc ccggtctgta tgaaaaagct tgacgtctgt taaagaatac ggtatccgtc
      421 caaaggcttc ttttaccaat gaggcatctt tcttctcacc acaggaataa ccaataattt
      481 ctcgattaaa caaatcaagt attaagcaga tataatgcca ctttttcccc acgcgaacat
      541 aagtaagatc cgtaacgatg gcttccaatg gctgttcttg tgtaaaggtc cgatctaata
      601 cattcgctgt tttcgcttca ttacaagctg ttcgttgccc tttaaaatga gcgatcgtat
      661 aggtagatgt caatccgcgg cgtttcatga ttcgaccgat tcggcgccga ctgagttgaa
      721 gcccacgctt tgctaaacac ttcttcaatt ttcgggtacc gtaagccttt cggtttcgaa
      781 taaactcttc ctgaacgatc tcttctaagt cggactcatt ttcgatcggt ttcgcttgat
      841 aatagtaggt
//
LOCUS       DAIGUC010000171          834 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.183, whole genome shotgun sequence.
ACCESSION   DAIGUC010000171 DAIGUC010000000
VERSION     DAIGUC010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.183"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            120..>834
                     /locus_tag="NOB46_002929"
     CDS             120..>834
                     /locus_tag="NOB46_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI1059787.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLSVDDKVHPLKLSWSIDRITIVG
                     KLKENIYYHTPNDVLILDFEQLMRLNEGNGYLRSVSNNGWQLLDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKNFIHDLFIEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRNGKLETAYWGSRSSERQIRMYNKKLEQEKKRKIVPKEIVSWWRLEMQ
                     LRRGKATDWHAMVRESLDSF"
BASE COUNT          279 a          117 c          180 g          258 t
ORIGIN      
        1 acgaatattt ttaggtttct tcaagactag agattttttg gtaatgaatt tttaagagtt
       61 acgtgaactt ttgaaaattc tttccagaag tctctttttt ctttgaggag gaactaaatt
      121 tgagtaaaaa aggcacgatc ataaatgagt gggaaaaatt aacagccccc tctaacaggc
      181 ggttaagtgt tgacgataag gtacaccccc taaaattaag ttggtcaatc gatcgaatta
      241 caatcgtcgg aaaactgaaa gaaaatattt attatcacac tccaaatgat gtgttgattt
      301 tagattttga acagcttatg cgcctaaatg aaggtaacgg ttatttaaga tctgttagta
      361 ataatggttg gcagttgtta gaccaacatg aagagaatat tgcttatatt gaaattttaa
      421 aatggcaaga ggggaaaggg cgtatagact tcaatccgaa taagattagt caattcttag
      481 ctagttccat gaaaaatttt attcatgatt tgtttatcga acctcacttt tcacgtgcag
      541 atattgcttg cgacattatc gatgtacctg atgagtttat tacacaatat cgggtagttg
      601 atccagtttc ttttaagcct atttatggac ggaatggaaa attagagacg gcatattggg
      661 gatctcgctc ttctgaacgt caaattcgga tgtataataa aaaactggaa caagagaaga
      721 aaagaaaaat tgtgccaaaa gaaatcgtga gttggtggcg gttagaaatg cagctaagac
      781 gtggcaaagc aacagattgg catgcgatgg ttcgggaaag tttagatagc tttg
//
LOCUS       DAIGUC010000172          797 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.184, whole genome shotgun sequence.
ACCESSION   DAIGUC010000172 DAIGUC010000000
VERSION     DAIGUC010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.184"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            100..630
                     /locus_tag="NOB46_002930"
     CDS             100..630
                     /locus_tag="NOB46_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059788.1"
                     /translation="MISDNKWEINLKRFISEYIYTIETKSSFSLNEDSDPLKKYTIQC
                     KKNKDEKLFVIRPDLMKSNTHYIKEKPKDCDYIIISEANKTVFLIELKSSAQTSPAKE
                     ISEQIDGGYKWLQHLSFLTKYDFTEFSYKIIKVCCKFEARQDRKNLFKPNEYGIYNMN
                     GPKLDLRELYRKCNDL"
     gene            complement(625..>797)
                     /locus_tag="NOB46_002931"
     CDS             complement(625..>797)
                     /locus_tag="NOB46_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059789.1"
                     /translation="KGRPKLYSADTKNPQRRLVYENIVKDLNEGVSISKIAKNYNVTR
                     QTIYRIKKDLNL"
BASE COUNT          312 a           96 c          123 g          266 t
ORIGIN      
        1 aatttctaac atcagttatt atgataattt tgatgatgtc aattatgatt tacaggaaag
       61 atataatgat ttaatcgaag aattagagga gagaggagaa tgatttcaga taataaatgg
      121 gaaataaatc tcaaaagatt tatttcagaa tatatatata cgattgaaac taaatctagt
      181 ttttctctta atgaagacag tgatcctcta aaaaaataca ctattcaatg taagaaaaat
      241 aaagatgaaa aattgttcgt aataagacca gatcttatga agagtaatac ccactatata
      301 aaagaaaaac ctaaagattg tgactacatc atcataagtg aagcaaataa aacagtattt
      361 ctgatagaac ttaaaagctc agctcagact tcccctgcaa aagaaattag tgaacaaatt
      421 gatggtggat ataagtggtt acaacatctt agttttctaa caaaatatga ttttactgaa
      481 ttcagttata aaattattaa ggtatgttgt aaatttgagg caagacaaga tcgtaaaaat
      541 ctttttaaac ctaatgaata tggtatttat aatatgaatg gtccaaaatt agacttaaga
      601 gagttgtata gaaagtgtaa cgatctataa attcaaatct tttttaattc tatatattgt
      661 ttgtctagta acgttataat tctttgcaat ctttgaaata gagacgccct cattcaagtc
      721 cttaacgatg ttttcataaa ctaaacgtcg ttgaggattt tttgtatctg cactatagag
      781 ttttggacga cctttat
//
LOCUS       DAIGUC010000173          792 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.185, whole genome shotgun sequence.
ACCESSION   DAIGUC010000173 DAIGUC010000000
VERSION     DAIGUC010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.185"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(62..262)
                     /locus_tag="NOB46_002932"
     CDS             complement(62..262)
                     /locus_tag="NOB46_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI1059790.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          256 a          133 c          122 g          281 t
ORIGIN      
        1 aattttttcg tacaaaaaaa ccgtcttttc tttcgaaaag acggttaaaa gtcaattttt
       61 attaagcttt aacaatgttt gttgcttgag ggccacgttg accatcttca acatcgtaag
      121 acactgcttg gccttcttct aaagttttga agccgtcacc ttggatagct gaaaaatgtg
      181 caaatacatc atttccatct tcaccagtga taaagccaaa acctttgtct gcgttgaacc
      241 attttactgt accgttattc ataaataaat tcctcctgat acgtatcaat gtacgttttt
      301 tcgttgcaat aaatatttga taggcaaaag gagttttatc tatgtagata tatcgctcaa
      361 attacgtttc aaaatagatt actcatttaa tatatcatgc tttttctaat aacacaagga
      421 taatgcaatg aaatataaaa ttcattgtct tctattgtct tcgaatcgaa gaaaaagttg
      481 aataaccgcg attgattcac tttttgtttt cttgtttatt tgcttttatc tgcaactttt
      541 gactttaaaa tttcttaact atgaaaacct ttcaattggt ggtatactta taaatggaat
      601 ttcgttatca acgcgttcgt tgcctttcag caagtattta aagaaaggag aatggctatg
      661 acattctata acaaagatat acaatatcga gtaaccttgg atacagattt gaatctattt
      721 gtcgtttttg acaaagaaaa taccaatcat gtagcgacag gtgttacgat cgaacaagca
      781 gtgcaagaat ta
//
LOCUS       DAIGUC010000174          790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.186, whole genome shotgun sequence.
ACCESSION   DAIGUC010000174 DAIGUC010000000
VERSION     DAIGUC010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.186"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..781
                     /locus_tag="NOB46_002933"
     CDS             <1..781
                     /locus_tag="NOB46_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1059791.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          339 a          107 c          102 g          242 t
ORIGIN      
        1 agatatgcta gattactact attttgaaaa aaatttatca tataattatg taatacattt
       61 aaaaactttt acaggaatga tttttaaatt cgccaaccgt cgatatggat taaaatataa
      121 tcccgtaaat ggggtttctt tagcaagaaa acctaagaca aacgaagaaa taaaaaaaga
      181 aaaagatggt tatttatcaa aagaagaagt tcaaatgatt gctagtaaac aaaaaagttc
      241 acatcaacag tcacgttatt ctttaattac taaatttttg tttttaactg gactacgtta
      301 tggtgaattg atatctttga ctgaatctga ttatgatggt aataaaatta cggtttctgg
      361 tacttatgat tacgagttaa aaattaaaac aacaactaaa aatacaggtt cttatagaac
      421 cattgaatta tcaagtaatg ctaaagaaat catagatcaa ttaattgaag aaaacaaatt
      481 aattaagaat aataaagata aatacatttt catctctaaa aatggtaacc cgatatctat
      541 tcaagcatat aatcaatctt taagagcagt atccaaagaa ttaaacatag ataaaaaagt
      601 ttcttctcac atgttaaggc attcccacat ttctctactt acagaattag gaatcccatt
      661 aaaagccatt atggatcgtg taggacatga agattcaaaa acaacattaa agatttatac
      721 tcatacaact aaaaatatgc aaaatcaact agtagaaaaa ctaggaaaaa tagaaattta
      781 aattgcccct
//
LOCUS       DAIGUC010000175          790 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.187, whole genome shotgun sequence.
ACCESSION   DAIGUC010000175 DAIGUC010000000
VERSION     DAIGUC010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.187"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            123..>790
                     /locus_tag="NOB46_002934"
     CDS             123..>790
                     /locus_tag="NOB46_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI1059792.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEV"
BASE COUNT          285 a          124 c          143 g          238 t
ORIGIN      
        1 ttttacactc tcataaaaga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
      661 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
      721 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
      781 aagaagtttt
//
LOCUS       DAIGUC010000176          697 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.188, whole genome shotgun sequence.
ACCESSION   DAIGUC010000176 DAIGUC010000000
VERSION     DAIGUC010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.188"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(54..629)
                     /locus_tag="NOB46_002935"
     CDS             complement(54..629)
                     /locus_tag="NOB46_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI1059793.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          230 a          151 c          125 g          191 t
ORIGIN      
        1 aatgaaaaaa cagagccaga ttagcattat tttgctaatc cagctctgtt tattcagcct
       61 atttttcttt ttgaatatat caagcgttgg ggcaacatag tgatgactaa tgaaacaacg
      121 acgatagaca acaagcgatc aaggtagtct gtacccgcct gtaccaagat cacacttgtt
      181 gtctgactta aacctaaccc atgtaatagc tgaacgatca tactggatcc tgaggaggtg
      241 atcccgccaa ataactgaac ggtaatgatc gaagaaacga tcgttccagg taccgacaaa
      301 atcaaagcga gtaataacag tttcaagctg tttttatctt tgccgagata tcttggcaaa
      361 atcaatccag caagcaagcc tgtgagaatt tggattggcg aataatacag agaaaaaata
      421 tctgtagtca ctccacttaa aataccgctg gacaatcctg tcagcattcc aggtacaggc
      481 ccaagcaatg caccagcaaa aatcgttccg atagaatcga gatagattgg caaacgaagc
      541 cataaagcaa tcgttcctcc aatataattg atcccaatac acaaagccat cactgtaagt
      601 acgcgagttg ccattttgtt tttattcatt ttgttagccc atctttaacc tttccaaatc
      661 tttcataatc gtttcttctt gtgcatttaa aagaacg
//
LOCUS       DAIGUC010000177          693 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.189, whole genome shotgun sequence.
ACCESSION   DAIGUC010000177 DAIGUC010000000
VERSION     DAIGUC010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.189"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..617)
                     /locus_tag="NOB46_002936"
     CDS             complement(<1..617)
                     /locus_tag="NOB46_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059794.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNK"
BASE COUNT          209 a          112 c          106 g          266 t
ORIGIN      
        1 aatttattat tatcaatttt ttgtccatca gaaagaatcg caaagtccat aatacctaag
       61 tcaataccaa ttgtggaatt agttttaggt aattcgataa tttcttcttt acacaacaaa
      121 gaaatatagt atttaccgct agaatgacgt gatattgtag cagatttgat aatccctttt
      181 ggttgtctat gaagcttaat tcttactaat gacttcaatt taggaacttt gatgaattta
      241 ctatcaatca aagcaactgt accattttga ttattcgttg tataactctg aacaggattt
      301 ttcttacttt tgaaacgtgg aaatccaacg gatttatccc gaaaaaaatt cttgtatgct
      361 ttatctaaat taagttgggc attggctaaa gcaaggctat caatttcttt caaaaacgga
      421 aattctttct tgtatttagc tggtgtcgga aaagtcattt ttttagaaga atcattttta
      481 acttcttcat acgccttttt tcggtcatca agcattagat tgtagacctt acggacacaa
      541 ccaaaagatt tggcaaagaa gatttcttgt tcctctgttg gatagattct gaatttgtat
      601 gcttttagtt gttccataaa gttcacctac tttctattta tgattgtttc cttgattttg
      661 gatatacttc ttaatcacat caattggtgc gcc
//
LOCUS       DAIGUC010000178          693 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.190, whole genome shotgun sequence.
ACCESSION   DAIGUC010000178 DAIGUC010000000
VERSION     DAIGUC010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..693
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.190"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
BASE COUNT          240 a          112 c          108 g          233 t
ORIGIN      
        1 tctgaagctg tattaaatac agatagatta atataaaaat caaaaggatc ataaactttt
       61 aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttatctca taacattgaa
      121 gtgttttgca attttagcat tgaaacactt ttttaatctt caacgttgtt cttataaaca
      181 agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt tatagaaaac
      241 attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc agtaggttcc
      301 cgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt atttaagaga
      361 ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta cacgtttttc
      421 tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc aagaaccgta
      481 ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa taagctatca
      541 agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta ggtttagcta
      601 agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt tttctcttaa
      661 ttcaactgaa tcaatattat tgttttgttc ata
//
LOCUS       DAIGUC010000179          683 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.191, whole genome shotgun sequence.
ACCESSION   DAIGUC010000179 DAIGUC010000000
VERSION     DAIGUC010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.191"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            83..683
                     /locus_tag="NOB46_002937"
                     /pseudo
     CDS             83..683
                     /locus_tag="NOB46_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          259 a          117 c          114 g          193 t
ORIGIN      
        1 tccatgttcc ccactcctca agtgttttct ttagtatacg cctataggag gaaaaacgaa
       61 tacaatttaa ctcaatttat ataataggaa aaatttagcc gaatctgaag gaattagtag
      121 agttactcta tatcaatgga aaaacacggt tcttggaaag gattttccat tgcgtatgac
      181 tttaaaaaat caggaaaaac aaaaagagct acttttaaag gaagtagaag acttacaaaa
      241 acaagtacac caattacagc tcgaaaaagc attactcgaa ggagcggctg aactgctaaa
      301 aaaagaaaaa ggcgtcaatc ttctttgtct atcaaatcaa gaaaaaacga tattgattga
      361 tgccttacga aatcagttca ccttgaaaga gcttcttcaa cagctccagt tgcctaaaag
      421 cagctatttt tatcaaaaac aagcacttga gaaaccagat aagtattaca aagaacgtca
      481 attaattatc acgattttca atcataactt ctgtgcgtat ggttaccgta gaattgacca
      541 agctttaaaa aatatgggta aaaagctttc tgaaaaagtt gtacgtagat tgatgactga
      601 ggaaaatcta tttgttaaat tttctagacg aaaaaagtat tcttcgtatg ctggggaaat
      661 ttctcctgca caccccaatt tat
//
LOCUS       DAIGUC010000180          678 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.192, whole genome shotgun sequence.
ACCESSION   DAIGUC010000180 DAIGUC010000000
VERSION     DAIGUC010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.192"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
BASE COUNT          240 a          113 c           80 g          245 t
ORIGIN      
        1 caaattactt catcaaaaca ttgatataat ttttattata tcagtattta ttcttgatac
       61 ataaatgaga aaataaatac tttaaatcta ttgactacaa gtagtcatta agtcttcata
      121 agatgtacaa tatgacatta aaaaaataaa agcttacgac catccgttaa atctgacact
      181 aaataatgga ctgctttctt ttgtattagc aggttacgtt gactatgaat attcaccaga
      241 ttatttggag aaacctcttc aacacgagaa caatgatatt aattttagat ttgtctacga
      301 gtcaaaaagt aaaacatggt tagttgatca attaagcacg ataaacacaa gcttccatga
      361 attacctaaa cctgaaaatg aagttgagat ggtcattaaa atcttctaaa aaagaagcgt
      421 tgaaggggaa atattccttt caacgctctt ttttatatgc ttagaaacat aaataaattg
      481 tatactttct ttttagcccc tattactttt cacgaaaaat atcttttttt cgacgctagc
      541 gtttctctac ttctaatact gtacacagtt tttgtattat tgaaaaatta ctcattattt
      601 agcattaatc cacatcgttt tatcaatcga ccttcatact aaactacttt aaagtcatct
      661 tccttctcgt ttttcatt
//
LOCUS       DAIGUC010000181          673 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.193, whole genome shotgun sequence.
ACCESSION   DAIGUC010000181 DAIGUC010000000
VERSION     DAIGUC010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.193"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(5..90)
                     /locus_tag="NOB46_002938"
     tRNA            complement(5..90)
                     /locus_tag="NOB46_002938"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="NOB46_002939"
     tRNA            complement(107..178)
                     /locus_tag="NOB46_002939"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="NOB46_002940"
     tRNA            complement(190..262)
                     /locus_tag="NOB46_002940"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="NOB46_002941"
     tRNA            complement(280..361)
                     /locus_tag="NOB46_002941"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="NOB46_002942"
     tRNA            complement(369..441)
                     /locus_tag="NOB46_002942"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="NOB46_002943"
     tRNA            complement(445..517)
                     /locus_tag="NOB46_002943"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
     gene            complement(531..646)
                     /gene="rrf"
                     /locus_tag="NOB46_002944"
     rRNA            complement(531..646)
                     /gene="rrf"
                     /locus_tag="NOB46_002944"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          168 a          191 c          160 g          154 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataacttaa gcgtggcgac
      541 gtcctactct cacaaggggc aacccctcac tacaatcggc gctaagaagc ttaacttctg
      601 tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt ggtgttatct
      661 tttattgagt aaa
//
LOCUS       DAIGUC010000182          671 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.194, whole genome shotgun sequence.
ACCESSION   DAIGUC010000182 DAIGUC010000000
VERSION     DAIGUC010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.194"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            69..383
                     /locus_tag="NOB46_002945"
     CDS             69..383
                     /locus_tag="NOB46_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059795.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            376..>671
                     /locus_tag="NOB46_002946"
     CDS             376..>671
                     /locus_tag="NOB46_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059796.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRP"
BASE COUNT          275 a           98 c          113 g          185 t
ORIGIN      
        1 gggtaaatct ctgagggagc aagctcccta cagactccct cccaaaaaaa gaaaggtgga
       61 agaaaaaaat gaactatcca tattttaaag tctcggcttc agaagaaact aaagaaatat
      121 tcaacaattt ttacaaccaa aacaaaggaa tttttggttc aaaggcaaat atgtttcgtg
      181 ttatggtttc aaatttacca gtgttagcta gtccatcaaa taataaattt aatgatcctg
      241 aaagcattaa atttgaacaa aaaatttcag aactagaatc aatgataagt aatgaagtaa
      301 ttgaaaagct ggatgacatt gatcaaaagt tatcgtattc tctaaaaaac aaatacaaaa
      361 cggaggagaa aaaagatgtt taaagtttac ttcccgtttc agtggctcgt taaaggaatt
      421 cttttagtgc tactaggatt gattcttttt ggaagttatc taacaattaa agccagacat
      481 tttccagaag aaaagccaat aaaaattgta acaaaagatt taaaaatagg tgaaacttat
      541 caggcagatg gggttgaact aacatttaaa aatattgaag tgaccgaaaa aagaaatgaa
      601 tttgcacaac atgatcgtgt attacaagtg acctatacac ttataaatga tacagaaaat
      661 ccgatacgtc c
//
LOCUS       DAIGUC010000183          637 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.195, whole genome shotgun sequence.
ACCESSION   DAIGUC010000183 DAIGUC010000000
VERSION     DAIGUC010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.195"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            51..>637
                     /locus_tag="NOB46_002947"
     CDS             51..>637
                     /locus_tag="NOB46_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HCI1059797.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEA"
BASE COUNT          231 a          106 c          126 g          174 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccat
//
LOCUS       DAIGUC010000184          613 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.196, whole genome shotgun sequence.
ACCESSION   DAIGUC010000184 DAIGUC010000000
VERSION     DAIGUC010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.196"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            44..379
                     /locus_tag="NOB46_002948"
     CDS             44..379
                     /locus_tag="NOB46_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059798.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
BASE COUNT          241 a           68 c          108 g          196 t
ORIGIN      
        1 aatttcctag gaaaaatagt taacataaaa ggaatgaatt gttatgaaac aatatttaaa
       61 tgaatggaaa gcgatagagg ggtcattagt aacgcaaaga ataaaggaat tacctgattg
      121 cttagagaag gatcatttgt ttcaaatacg agaaatgttg aaaaaagaac agtttgatcc
      181 agaccaattt ttagtagtcg agtatccaac tattggagtg tactgttgta accatatcaa
      241 tgatggaaaa tattttatta ttcaggagta tggaggacag ttaactcctt tctatactac
      301 atgggaaatg agtgaagaag gaatcaataa ttttccatgt gaaagcatcg aagattcaat
      361 ttcacacacc gaatgttaat tgattataac tataaaaaag gattgaacat tatgttcaat
      421 ccttttttca atgaaatgtt ttccgccatt tcattgtttg gtgcgatttc tattttatta
      481 tatcaaaata aagagagatt ctaaagaaag aagagggaaa tatataaatc aagcgacagt
      541 atatttatta ttaaatgcta ttgtgagaat ataactaatt agtttaattt gaaagtaaat
      601 atacgctata aaa
//
LOCUS       DAIGUC010000185          584 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.197, whole genome shotgun sequence.
ACCESSION   DAIGUC010000185 DAIGUC010000000
VERSION     DAIGUC010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.197"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..489
                     /locus_tag="NOB46_002949"
     CDS             <1..489
                     /locus_tag="NOB46_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059799.1"
                     /translation="LSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLN
                     KLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIK
                     VDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMG
                     LA"
BASE COUNT          212 a           88 c          114 g          170 t
ORIGIN      
        1 ttgtctaggc gtgctttatt ggctaaaaat aaaggtacca atctatttga agctaaaaat
       61 tatcaaaaac aaaaacgcaa agtagctaga ttgcatgaaa aagtaatgaa tcaacgtact
      121 gattttctga ataagttgag tacagaaatg atcaaaaatc acgatattat ctgtattgaa
      181 gacttaaaca caaaaggtat gttgcgaaat cataaattag ctaaaagtat ttctgatgtt
      241 tcttggtcaa agtttgtgac taaattacaa tacaaggctg actggtatgg acgaaaaatc
      301 atcaaagtag ataaatggtt tccgtctagt cagatttgtt cagagtgcgg acataaagat
      361 ggcaagaaat ctcttgaaat tcgagaatgg acttgtcctg tttgtcatac tcatcatgat
      421 cgtgatatca atgctagtat caatattctg accgaaggtc taagactaca ttctatggga
      481 ttggcttaga tccaatcatc aagaaccgta ggaactacgg ggatagcttg gtaaataaga
      541 gacaccgctg ttagtaaaga aatacgctat caagtatgct ctat
//
LOCUS       DAIGUC010000186          583 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.198, whole genome shotgun sequence.
ACCESSION   DAIGUC010000186 DAIGUC010000000
VERSION     DAIGUC010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.198"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>583
                     /locus_tag="NOB46_002950"
     rRNA            <1..>583
                     /locus_tag="NOB46_002950"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          174 a          126 c          167 g          116 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc gga
//
LOCUS       DAIGUC010000187          579 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.199, whole genome shotgun sequence.
ACCESSION   DAIGUC010000187 DAIGUC010000000
VERSION     DAIGUC010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.199"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>579
                     /locus_tag="NOB46_002951"
     rRNA            <1..>579
                     /locus_tag="NOB46_002951"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          114 c          173 g          120 t
ORIGIN      
        1 aaagcacccc ggaaggggag tgaaatagaa cctgaaaccg tgtgcctaca acaagtcaaa
       61 gcccgttaat gggtgatggc gtgccttttg tagaatgaac cggcgagtta cgattgcatg
      121 cgaggttaag ttgaagagac ggagccgcag cgaaagcgag tctgaatagg gcgtttgagt
      181 atgtagtcgt agacccgaaa ccatgtgatc tacccatgtc caggttgaag gtgcggtaaa
      241 acgcactgga ggaccgaacc cacgtacgtt gaaaagtgcg gggatgaggt gtgggtagcg
      301 gagaaattcc aaacgaactt ggagatagct ggttctctcc gaaatagctt tagggctagc
      361 ctcggaattg agaatgatgg aggtagagca ctgtttggac taggggccca tctcgggtta
      421 ccgaattcag ataaactccg aatgccattc attcatatcc gggagtcaga ctgtgagtga
      481 taagatccat agtcgaaagg gaaacagccc agaccaccag ctaaggtccc aaaatatatg
      541 ttaagtggaa aaggatgtgg ggttgcacag acaactagg
//
LOCUS       DAIGUC010000188          568 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.200, whole genome shotgun sequence.
ACCESSION   DAIGUC010000188 DAIGUC010000000
VERSION     DAIGUC010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.200"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>568
                     /locus_tag="NOB46_002952"
     CDS             <1..>568
                     /locus_tag="NOB46_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI1059800.1"
                     /translation="KGKGRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVRE
                     IRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKL
                     AKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYK
                     EVPKHQHKRALVLTARKFTRLVDTLLRKH"
BASE COUNT          212 a          109 c          103 g          144 t
ORIGIN      
        1 aaaggaaaag gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt
       61 accatgagtt accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt
      121 ctcgtacgag aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa
      181 caagtaattg ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa
      241 gtctatgctg ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca
      301 aaattggcaa aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg
      361 caaaatacac ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct
      421 gccaactctg taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag
      481 gaggttccaa agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt
      541 ctggtggata cgctactacg taaacacc
//
LOCUS       DAIGUC010000189          558 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.201, whole genome shotgun sequence.
ACCESSION   DAIGUC010000189 DAIGUC010000000
VERSION     DAIGUC010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.201"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            144..>558
                     /locus_tag="NOB46_002953"
     CDS             144..>558
                     /locus_tag="NOB46_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI1059801.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLE"
BASE COUNT          221 a           77 c          104 g          156 t
ORIGIN      
        1 gaagtagaaa aagaatattt cgaatattgg atagaaaagc aaactagacc gggtacgaaa
       61 gaagagtatt cccaaaaagt tgatcggaat ttaattcact caattcagat tattgcaagt
      121 ttaaaagatg aggtgaaaca actttgggag ctactataac atcgaaagga cgcaagaaaa
      181 atttatcctc gctattacaa tatgcagcta atccttcaaa aaaagaaaaa tgtgttgcag
      241 tctcaggaat aaattgtagt gatgatagtg aggaagcact gcaagaaatg aatttagtac
      301 gtaccaagat gaataaatct aaagatatag cacaagcgtt tcatgttatt cattcgtttg
      361 ataagagtac ttctaaagag ttaagtattg ataaaatgca cgaaatagct gtcgaatttg
      421 cagagaaagc ttttccaaat tcgcaaatca ttgttgcaag tcacaatgat aaagatcatt
      481 ttcatagtca tcttgtcatt aataatatta acatggaaac atgtaaaagg ttgcgtattg
      541 accctaaaga tttagaac
//
LOCUS       DAIGUC010000190          526 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.202, whole genome shotgun sequence.
ACCESSION   DAIGUC010000190 DAIGUC010000000
VERSION     DAIGUC010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.202"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            6..398
                     /locus_tag="NOB46_002954"
     CDS             6..398
                     /locus_tag="NOB46_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1059802.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
BASE COUNT          208 a           35 c           92 g          191 t
ORIGIN      
        1 agtttatgga agaagtttta attgatgata atatggtttt tgatattgat aatttaaaag
       61 gatttcttaa tgataccagt tcatttgggt ttatagctaa agaaaataat aaaattatag
      121 gatttgcata ttgctataca cttttaagac ctgatggaaa aacaatgttt tatttacact
      181 caataggaat gttacctaac tatcaagaca aaggttatgg ttcaaaatta ttatctttta
      241 ttaaggaata ttctaaagag attggttgtt ctgaaatgtt tttaataact gataaaggta
      301 atcctagagc ttgccatgta tatgaaaaat taggtggtaa aaatgattat aaagatgaaa
      361 tagtatatgt atatgattat gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa
      421 tatgtataag aactttaata gatgatgatt ttcctttgat gttaaaatgg ttaactgatg
      481 aaagagtatt agaattttat ggtggtagag ataaaaaata tacatt
//
LOCUS       DAIGUC010000191          508 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.203, whole genome shotgun sequence.
ACCESSION   DAIGUC010000191 DAIGUC010000000
VERSION     DAIGUC010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.203"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(77..149)
                     /locus_tag="NOB46_002955"
     tRNA            complement(77..149)
                     /locus_tag="NOB46_002955"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
BASE COUNT          162 a          112 c           83 g          151 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaa
//
LOCUS       DAIGUC010000192          493 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.204, whole genome shotgun sequence.
ACCESSION   DAIGUC010000192 DAIGUC010000000
VERSION     DAIGUC010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.204"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..>493)
                     /locus_tag="NOB46_002956"
     CDS             complement(<1..>493)
                     /locus_tag="NOB46_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HCI1059803.1"
                     /translation="GELITLGRDKQSRKEKSQYVERTFSARKLGKRYSFESVSEQLEK
                     NLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQKQFSDREGDEKFIK
                     YDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTISIKKTDQKELFLP
                     AKGF"
BASE COUNT          142 a           97 c           60 g          194 t
ORIGIN      
        1 aaaacccttt gccggtagaa ataactcttt ctgatcagtc tttttaatag aaattgtttt
       61 acttttcgca ctacgtaaag tttgaggatt cacatccgta tgaagtttaa tcgtgtattc
      121 ttgatcatct tctaaagaca ttgtatttac aaaatgcttg tctacctctc gcaagaagtc
      181 atcatattta atgaattttt catcgccttc acggtcgcta aattgctttt gtgcgatgga
      241 atctaattcc acaaacggta catttaactc accagttttg taatttactc cactaattag
      301 cgacataact tgctctcttt ccatattaaa aaaatttttt atatgtgatt cttctaaatt
      361 cttttcaagt tgttcagaaa cagattcaaa tgaatatctt ttccctaact ttcttgcact
      421 aaaagtacgt tcgacatact gacttttttc ttttctagat tgtttatctc ttcctaaagt
      481 aattaactca cct
//
LOCUS       DAIGUC010000193          480 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.205, whole genome shotgun sequence.
ACCESSION   DAIGUC010000193 DAIGUC010000000
VERSION     DAIGUC010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.205"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            136..>480
                     /locus_tag="NOB46_002957"
     CDS             136..>480
                     /locus_tag="NOB46_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059804.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          214 a           65 c           69 g          132 t
ORIGIN      
        1 aacatttaca aaattagcta aagctgaaca atatagacga tctttagaat tgtcaaaaga
       61 ttaaatatat aaaaagcctt cgggcttttt cttttaacaa ttaataggaa cgtatattcg
      121 aaaggaatag aaataatgtg gttagaaaaa ataaatgaca aaaaatttaa gtacaccgaa
      181 cgttatacgg atcccttaac tgaaaaaaag agaaaagtgt ccgttacttt atctagcaat
      241 tcacgccaag cttggaatca agctaactta cttttgaatg aaaaaatcgc agaaaaaata
      301 aaacgaaatg aagaattacc actaactttt ggagaattaa aaactaaatg ggatgaaaaa
      361 tacaagccaa ctgtaaaaga aagttcctat cgaacaactc aggtttatct atcattaatt
      421 tcaaaatata taaaagatga tgtacttgta aaaaacgtta atagtaatct tatacaagat
//
LOCUS       DAIGUC010000194          460 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.206, whole genome shotgun sequence.
ACCESSION   DAIGUC010000194 DAIGUC010000000
VERSION     DAIGUC010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.206"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(20..91)
                     /locus_tag="NOB46_002958"
     tRNA            complement(20..91)
                     /locus_tag="NOB46_002958"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="NOB46_002959"
     tRNA            complement(113..200)
                     /locus_tag="NOB46_002959"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="NOB46_002960"
     tRNA            complement(225..298)
                     /locus_tag="NOB46_002960"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="NOB46_002961"
     tRNA            complement(312..382)
                     /locus_tag="NOB46_002961"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="NOB46_002962"
     tRNA            complement(384..459)
                     /locus_tag="NOB46_002962"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAIGUC010000195          451 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.207, whole genome shotgun sequence.
ACCESSION   DAIGUC010000195 DAIGUC010000000
VERSION     DAIGUC010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.207"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
BASE COUNT          143 a           90 c           68 g          150 t
ORIGIN      
        1 gacactcctc ttaatataca gtcctattgt ataaagtgtt actatataca tagtaactgt
       61 atacataaaa aaagtcaagt attagaaaaa agttcaaaag atcaagtgtg cgcttcgctc
      121 ccactcccct cgacgtttta gtagcctttc cctcacttcg ttcagtccaa gccaactaaa
      181 aagttttcgg gatacattct ccttctcttc ctaataatca attaaaattt taatctttat
      241 atttctgcta atcactcagg aaacagtaca gaaaaacaaa cacgtatcat agatataaat
      301 gtaatggcat agtgcgggtt ttattttcag cctgtatcat agctaaacaa atcgagttgt
      361 gtgtccgttt ttgggcgttc tgctagcttg tttaaagtct cttgaatgaa tgtatgttct
      421 aagtcaaaaa actctgacag cgcctttata t
//
LOCUS       DAIGUC010000196          448 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.208, whole genome shotgun sequence.
ACCESSION   DAIGUC010000196 DAIGUC010000000
VERSION     DAIGUC010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.208"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>448
                     /locus_tag="NOB46_002963"
     CDS             <1..>448
                     /locus_tag="NOB46_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HCI1059805.1"
                     /translation="DTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEFGHL
                     EGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFKSIT
                     FDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGL"
BASE COUNT          147 a           93 c           81 g          127 t
ORIGIN      
        1 tgacacacta ccgatgaaag gtaaaagaaa acccaatggc catcaggaaa aacggggaaa
       61 acaacagtat cagcgctcaa tccatgatcg acctgataat tatcctgatt tcaattctga
      121 gtttggtcac cttgaaggtg atacgatcgt tggcattcat cataaaagtg ccgtcattac
      181 tttagttgaa agattatcta aagtcattat cacgattaaa cccaacggcc gtaaggcatt
      241 agatattgaa actgccctta atcaatggtt ttctcgcttc cctaaaaact tctttaaatc
      301 tattacgttt gactgtggaa aagaattttc taactggaaa gccattagta accaacatga
      361 tattgatata tattttgcgg accctggaac accttctcaa cgcccattaa acgagaattc
      421 taacgggatt ctgcgtcgta atggactg
//
LOCUS       DAIGUC010000197          442 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.209, whole genome shotgun sequence.
ACCESSION   DAIGUC010000197 DAIGUC010000000
VERSION     DAIGUC010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.209"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>442
                     /locus_tag="NOB46_002964"
     rRNA            <1..>442
                     /locus_tag="NOB46_002964"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          100 a          112 c          142 g           88 t
ORIGIN      
        1 ttatggccac tctaacccgc accactaatc gtggtgggag acagtgtcag atgggcagtt
       61 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
      121 ttggaaatca ttcgaagagt gtaaaggcag aagggagctt gactgcgaga ccaacaagtc
      181 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gcatggaagg gccatcgctc
      241 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtc cacatcgacg
      301 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
      361 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
      421 tcggtcccta tccgtcgcgg gc
//
LOCUS       DAIGUC010000198          427 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.210, whole genome shotgun sequence.
ACCESSION   DAIGUC010000198 DAIGUC010000000
VERSION     DAIGUC010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.210"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..>427)
                     /locus_tag="NOB46_002965"
     CDS             complement(<1..>427)
                     /locus_tag="NOB46_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059806.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDEL"
BASE COUNT          125 a           76 c           87 g          139 t
ORIGIN      
        1 agttcatcca atgtgaaatc ttccgtcatg agtgaaatga gggttgcact aaaaagactc
       61 gtcgattcgt ctcgcatttc tcgagcaagc gtattacatt tgtacgttag attttcaaga
      121 aaatgttgct ttgtacgaat caattgctta ataagttgat agcgagtacg tgttaaacgc
      181 tgtaaggcca tgtatttctc ttctttgata ggggaagttg tgaatcgttg aatacgcaag
      241 aaatcagcga ttcttaatgc atcgtttcga tcagttttat tctcatcaaa catgcgacta
      301 aattgtttca cccgaaaagg attttcaatc gttacaagtg tgttgagctt ctttagtttc
      361 tcatcttcat gaaaaaacat ggaaggatgg aagctgtaca tggacgttga ctccatgcca
      421 atcacaa
//
LOCUS       DAIGUC010000199          416 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.211, whole genome shotgun sequence.
ACCESSION   DAIGUC010000199 DAIGUC010000000
VERSION     DAIGUC010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.211"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..>416)
                     /locus_tag="NOB46_002966"
     CDS             complement(<1..>416)
                     /locus_tag="NOB46_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI1059807.1"
                     /translation="AEKAFPNSQIIVASHNDKDHFHSHLVINNINMETYKRLRIDPKD
                     LERMRKINDQVLNEHGLESVNNEYYENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIE
                     ATLEKCEVNSFEDFSDHLAKEYNIEVYQFSKTNNKL"
BASE COUNT          122 a           68 c           58 g          168 t
ORIGIN      
        1 caagtttgtt atttgttttt gaaaattgat aaacttcaat gttatattct tttgccaaat
       61 gatccgaaaa atcttcaaaa gaattcactt cgcatttttc caacgttgct tcgatcgcat
      121 tttgcacaaa ctcttgataa ttaatttttc catatttcat cttagaagga tcgtttgaat
      181 aaagattggt tctcttttct aagttttcat agtactcatt attcactgat tcaagaccat
      241 gttcattgag gacttgatcg ttaatttttc gcattcgttc taaatcttta gggtcaatac
      301 gcaacctttt atatgtttcc atgttaatat tattaatgac aagatgacta tgaaaatgat
      361 ctttatcatt gtgacttgca acaatgattt gcgaatttgg aaaagctttc tctgca
//
LOCUS       DAIGUC010000200          398 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.212, whole genome shotgun sequence.
ACCESSION   DAIGUC010000200 DAIGUC010000000
VERSION     DAIGUC010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.212"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>398
                     /locus_tag="NOB46_002967"
     CDS             <1..>398
                     /locus_tag="NOB46_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059808.1"
                     /translation="INTLLRTELTAFLDYEKYDRTGFNSGNSRNGSYFRSIKTEYGEL
                     TLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIADLIEKMYGHHYTP
                     QTMSNMTKVLTEEVNAFKSRALNDKYVAIF"
BASE COUNT          145 a           73 c           65 g          115 t
ORIGIN      
        1 cgataaacac actcctacgg actgaattaa cggctttttt agattacgaa aaatatgatc
       61 gcactggttt taattcaggt aattcgagaa acggttctta ctttcgatca atcaaaaccg
      121 aatatggtga attaacattg gaaataccta gagatcgtaa tggtgagttt aaacaacaaa
      181 ctttaccagc ctacaaaaga acaaacgata cattggaaac cactattatc catttattcg
      241 aaaaaggtgt tacgatgtct gaaattgctg atttgatcga aaaaatgtac ggtcatcact
      301 atactccaca aaccatgtcc aacatgacta aagttctgac tgaagaagta aatgccttta
      361 aatccagagc cttaaatgat aagtatgtcg ctattttt
//
LOCUS       DAIGUC010000201          381 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.213, whole genome shotgun sequence.
ACCESSION   DAIGUC010000201 DAIGUC010000000
VERSION     DAIGUC010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.213"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(21..94)
                     /locus_tag="NOB46_002968"
     tRNA            complement(21..94)
                     /locus_tag="NOB46_002968"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="NOB46_002969"
     tRNA            complement(108..181)
                     /locus_tag="NOB46_002969"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="NOB46_002970"
     tRNA            complement(209..281)
                     /locus_tag="NOB46_002970"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="NOB46_002971"
     tRNA            complement(301..374)
                     /locus_tag="NOB46_002971"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
BASE COUNT          103 a          108 c           90 g           80 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat t
//
LOCUS       DAIGUC010000202          380 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.214, whole genome shotgun sequence.
ACCESSION   DAIGUC010000202 DAIGUC010000000
VERSION     DAIGUC010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.214"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..376
                     /locus_tag="NOB46_002972"
     CDS             <1..376
                     /locus_tag="NOB46_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI1059809.1"
                     /translation="ICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQD
                     LLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQK
                     FLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          146 a           70 c           57 g          107 t
ORIGIN      
        1 aatctgtgat gactttaagg ctgtttatca agctaactca aaagaagaag cgaatacctt
       61 cttatccggc atgattgaga aatggaagaa aaactatcct aaagtgacgc agtcactcat
      121 agaaaaccaa gacttattaa ctttttatga ttttccacct agcattcgta gaaccattta
      181 ctcaaccaat ctaatcgagt ctttcaataa gcaaattaaa agatacagcc gtagaaaaga
      241 gcagtttcaa aatgaagaat cactagaacg ctttctagtc agcatttttg atacatacaa
      301 tcaaaaattt ctaaacagaa gccataaagg ttttcaacag gtaaccgata cattagtttc
      361 aatgtttact gagtaactaa
//
LOCUS       DAIGUC010000203          375 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.215, whole genome shotgun sequence.
ACCESSION   DAIGUC010000203 DAIGUC010000000
VERSION     DAIGUC010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.215"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..132)
                     /locus_tag="NOB46_002973"
     CDS             complement(<1..132)
                     /locus_tag="NOB46_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI1059810.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DAIGUC010000204          323 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.216, whole genome shotgun sequence.
ACCESSION   DAIGUC010000204 DAIGUC010000000
VERSION     DAIGUC010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.216"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="NOB46_002974"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="NOB46_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HCI1059811.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT          100 a           49 c           51 g          123 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttg
//
LOCUS       DAIGUC010000205          321 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.217, whole genome shotgun sequence.
ACCESSION   DAIGUC010000205 DAIGUC010000000
VERSION     DAIGUC010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.217"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>321
                     /locus_tag="NOB46_002975"
     rRNA            <1..>321
                     /locus_tag="NOB46_002975"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          108 a           64 c           87 g           62 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac t
//
LOCUS       DAIGUC010000206          321 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.denovo.218, whole genome shotgun sequence.
ACCESSION   DAIGUC010000206 DAIGUC010000000
VERSION     DAIGUC010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.denovo.218"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            complement(69..321)
                     /locus_tag="NOB46_002976"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="NOB46_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAIGUC010000207        14066 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.065, whole genome shotgun sequence.
ACCESSION   DAIGUC010000207 DAIGUC010000000
VERSION     DAIGUC010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.065"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..251
                     /locus_tag="NOB46_002977"
     CDS             <1..251
                     /locus_tag="NOB46_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI1059812.1"
                     /translation="LEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAKSNIGIDN
                     LIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            486..722
                     /locus_tag="NOB46_002978"
     CDS             486..722
                     /locus_tag="NOB46_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI1059813.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            729..2681
                     /locus_tag="NOB46_002979"
     CDS             729..2681
                     /locus_tag="NOB46_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI1059814.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2753..3250)
                     /gene="dfrG"
                     /locus_tag="NOB46_002980"
     CDS             complement(2753..3250)
                     /gene="dfrG"
                     /locus_tag="NOB46_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI1059815.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3612..4652
                     /locus_tag="NOB46_002981"
     CDS             3612..4652
                     /locus_tag="NOB46_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI1059816.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4750..4938
                     /locus_tag="NOB46_002982"
     CDS             4750..4938
                     /locus_tag="NOB46_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI1059817.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4996..5349)
                     /locus_tag="NOB46_002983"
     CDS             complement(4996..5349)
                     /locus_tag="NOB46_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059818.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5880..6302
                     /locus_tag="NOB46_002984"
     CDS             5880..6302
                     /locus_tag="NOB46_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI1059819.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6299..6529
                     /locus_tag="NOB46_002985"
     CDS             6299..6529
                     /locus_tag="NOB46_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059820.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            7027..7227
                     /locus_tag="NOB46_002986"
     CDS             7027..7227
                     /locus_tag="NOB46_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCI1059821.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7254..8447
                     /locus_tag="NOB46_002987"
     CDS             7254..8447
                     /locus_tag="NOB46_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI1059822.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8515..10080)
                     /gene="guaA"
                     /locus_tag="NOB46_002988"
     CDS             complement(8515..10080)
                     /gene="guaA"
                     /locus_tag="NOB46_002988"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI1059823.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10139..11062)
                     /locus_tag="NOB46_002989"
     CDS             complement(10139..11062)
                     /locus_tag="NOB46_002989"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI1059824.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11258..11863
                     /locus_tag="NOB46_002990"
     CDS             11258..11863
                     /locus_tag="NOB46_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI1059825.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12171..13187
                     /locus_tag="NOB46_002991"
     CDS             12171..13187
                     /locus_tag="NOB46_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI1059826.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13328..>14066
                     /locus_tag="NOB46_002992"
     CDS             13328..>14066
                     /locus_tag="NOB46_002992"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HCI1059827.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEA"
BASE COUNT         4677 a         2461 c         2699 g         4229 t
ORIGIN      
        1 ttttagagaa atatatgtcc ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa
       61 gcataagatt tcagaattgt tctctgttcc ctctttatca tggaagtgca aaaagtaata
      121 tagggattga taaccttata gaagttatta ctaataaatt ttattcatca acacatcgag
      181 gtccgtctga actttgcgga aatgttttca aaattgaata tacaaaaaaa agacaacgtc
      241 ttgcatatta agtagttcag ttttggagta caaaaagtga aaatgtaaac ctaaatgagt
      301 atcaaattgc aactgaattt gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa
      361 tttacaccac aaaatgtaag ttaaaatgta tataaaaatg cgaacgtgaa ataattattg
      421 taggaatgca aattggtgtg ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt
      481 ttcctatgca atttcttgag ccaaaaaata agaacgctaa gtctgtggat tgggaaatat
      541 cagagcaagt aagggtgata gttaagcaat acgctgaata tgcagagcgt actgaaagcg
      601 aagcagtgga tgaattctta ttgaacattt tagacgataa gaagtttatt gaatggattg
      661 ccaacaagcg aagtaataag cggattgttg aaaaaatggg tatcaaagat agagtgggtt
      721 gatagacaat gaccaagctt aaaagattag ccacgaagga agatgaaatt gtagatgtta
      781 aaattccgat ttcaaacgaa gaattaaaag atagggctaa acaatatgat ttattaactc
      841 caaaacgatt tgcaacaagg tataacaaaa tgttgttctt gccaacgtct tttaaatgga
      901 acggttctga atatcccatt caatataatt actgcatcaa tccgttttgt tgtaattttg
      961 ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc aagtcgatat aaaatgactg
     1021 gtagttccaa agataaaggt cataaaggta tgtactgcaa tgacaatcct attggcagag
     1081 gtgtatcgca aaactgtaca gtaacccctt tatctaattg gtctgttgtt gaagaaatta
     1141 aacgccttat agaaatcaat agcatccaag atgttgagcc agattatcaa tttcataaag
     1201 aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg
     1261 ggaaaagtag gggcaaatct caacgctatc aatgtaaggc gtgtaagaag ttcactaatg
     1321 ttctaccaaa aagagaagaa accactactt atcaccaaca aaagaacacc attcttccaa
     1381 tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg tacttgtgat attttaggaa
     1441 ttggagttgg aacctactat cataagctgg agtggctgta taggcgttgt ttggagtttt
     1501 tagaacgata tgagacacaa ccccttcaaa caaagaaatt taacgagatg tggcttaata
     1561 cggacaagat gcactactac ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat
     1621 atacggggtt tgaagacctt aatatgcaaa cgtatatagt tgtatctgct gaggtcttat
     1681 caagatatgt gttccgttct gatgttgcct atgattggaa tatttcaatg gatgaattaa
     1741 atgaagatac aagaaaattc aaagaagacc atctcaatac ttttagtcgt aaaaatgata
     1801 ggttagattg gtcttattat ccacaagaac catccgctaa cgatagcgaa aataggaatg
     1861 cttatcttca cgaattaggg aaaattacta ataggagtag atttgtcgat ggtttaaatg
     1921 ttgatgctcc ttatactaca actgctcact attggttaat taaacaaatg gttaatgccg
     1981 acgaatggcg aatgattagt gatgatgact tctctattag aaacgccttt tatagagtat
     2041 tcacgaaaga attaaggttg agcgatgcac atcattttat ttgccaagtt aacaagacga
     2101 aaagcagaaa acaatgctta aaagaattcg gacaagcaaa agcagaactg ctcgattggg
     2161 gagatatcag aggattcaaa acaaagtttc tacggacttt ggcatctcat tatctaactg
     2221 aattactaac aagtcatcaa ttccacgaag aggctattag taaagatgga gaaagatatc
     2281 gcaaatatgc cgataaccct atcaaacatc cattagccac taaggataaa ggattttatt
     2341 cagttgattg tagaacggat ttatctgctc tggaaccaaa cgaaatcgca aagatgctat
     2401 taaatgttaa tgaccattcg accaatagct ttattcaaca gataagacgt tatatatcat
     2461 ctcttgaaag accattaaca acagctcgtg gtgataagaa gagctatatt tacgctaact
     2521 tcaatccgaa gtatgctcaa tttgcgatta caattctaag aacttactac aacttttgtc
     2581 gcccttttaa atcagcggat aaaaaggttt tgacacctgc tcaaagatta gggattacag
     2641 ataaacaatt tgattggaaa gatataattt atttcaaatg acaaaaagag cttggagtaa
     2701 tcccaagctc ttgtgcttta tctttactgt tcttcttcaa ttaacgcacc cgttaactca
     2761 ataagttttt tctttcatat acatgaaaat agtagttata cggattttta tcattcttta
     2821 tccctttttg ggcaaatacc tcattccatt cctcataatt cacttctgga aaaaaagtat
     2881 ctccttcgaa ttcatgatgt atttttgtga tgtacatttt ctcaacataa gggaaaaaca
     2941 aattataaat ctgttctcct ccgaaaataa aaatttcttc ttcgttttta cataactcaa
     3001 aaacatcttc tattgaatga acaatttcac aaccattaaa ggtaaacccc ttatctctcg
     3061 tcagaataat atttcttctg tcaggtaagg ctcttccgat tgattcaagg ttcttcctac
     3121 ctaatattat cggatgtccc tttgtagtat ttttaacata ttcccagtcc ttgggaatcc
     3181 tccaaggaat gtcattctct ttgccaatca ctctattctt atccatcgca gcaatcaaag
     3241 aaactttcat ttataacaca gcctttttaa ctaatttacc atctaatttc ttatttctat
     3301 caaaaaacct tttctcatta tcctgcccgt tagttgaata agcaattttt tctataagtt
     3361 atattatcat aataccacaa aatcacaaat tttcattcaa ttatcatttt caattgcatt
     3421 ttataaatca ttttgtatgt aatttggtat gtaagttaaa atgaaaaaag tagtccattt
     3481 tgaagtacat tttgtcattt tgtactccaa aactgaacta cttacttgca tatatacgcc
     3541 tttatagtgg agtactacat ttacgagatt cggttagagt atcagaaaaa gaaaaaataa
     3601 aagttacaga aatgtatact tcaataaatg gtgaattatg taagattgat agagcttatt
     3661 ctggagaaat tgttattttg caaaatgagt ttttgaagtt aaatagtgtt cttggagata
     3721 caaaactatt gccacagaga aaaaagattg aaaatccgca ccctctacta caaacaactg
     3781 ttgaaccgag taaacctgaa cagagagaaa tgttgcttga tgcccttttg gaaatctcag
     3841 atagtgatcc gcttctacga tattacgtgg attctacgac acatgaaatt atactttctt
     3901 tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg
     3961 agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa aatgcagaat
     4021 ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt ttatctgtat
     4081 caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt ggatacttaa
     4141 atcaatcatt tcaaaatgca gttatggaag ggatacgcta tggttgcgaa caaggattat
     4201 atggttggaa tgtgacggat tgtaaaatct gttttaagta cggtttatac tatagccctg
     4261 ttagtactcc agcagatttt cggatgctta ctcctattgt actggagcaa gcctttagaa
     4321 aagctggaac agaattgtta gagccatatc ttagttttaa agtttatgca ccacaggaat
     4381 atctttcacg ggcatataac gatgctccca aatattgtgc aaatatcgta aatactcaac
     4441 tgaaaaataa tgaggtcatt attattggag aaattcctgc tcgatgtatt caagattatc
     4501 gcaatgattt aacttttttt acaaatgggc ttagtgtttg tttagcagag ctaaaaggat
     4561 atcaggttac cactggcgaa cctgtttgcc agacccgtcg tctaaatagt cggatagata
     4621 aagtaagata tatgttcaat aaaataactt agtgcgtttt atgttgttat ataaatatgg
     4681 tttcttatta aataagatga aatattcttt aatatagatt tgaattaaag tggaaaggag
     4741 gagattgtta ttataaacta caagtggata ttgtgtccta tttgtggaaa taaaacaaga
     4801 ctacgaatac gagtggatac tatacttaaa aatttccctt tatactgccc caaatgtaag
     4861 aacgaaactt taattaatgt tcaaaaaatg aatataataa caatcaaaga gccagacgcc
     4921 aagacgcaga gccgataatt tgagaaatga aactctcatc ttatcggctc tttttgttta
     4981 tctgaatttt actgactagc cttcaatatt tcttgcttca ttgatacctt ttgctagtgc
     5041 ttccattaag gatagttctt tgtctgtaaa gctatccatg tatttttcta cctgtaacct
     5101 tcgagtgctt ttaatcaaat tatctgtagg taagaaaaat tcatcaatag atacatggag
     5161 taatgataca agatcataca gcacttgtgt acttgggtgt tgtcctttgt tttctatatt
     5221 tgttaaataa cgtgggtcaa tttcaatcat tgttcccact tgttcacgag tgagaccccg
     5281 tttcattcga gcctctttaa tcgctaaacc aacggctcta aaatcgtatt tatcttcttt
     5341 tttacgcata ctaaatcacc tctatacatt ttactgttcc tatataacca taaacaggta
     5401 tagaaaaaca tgttatatag tttatgagtt cctatagaac actgtggaat ttattaatgc
     5461 gatgaatcca atttcaaata gaaaggtcgc tgattttatt tacctataca actttataaa
     5521 atttagtcat actcctagaa agtagataaa attggcgact taatggaggg aaaagtcgcc
     5581 atgagaaaga taatctgtca tctagttctc ttaattaagt tcttatcaaa aaaacttatc
     5641 cacctgtact ggatagatat gaccatcaat gtggttttgc agattacata gatagaaaaa
     5701 tcaaagcata tgaacagaga aaacaatctg tttatgtgct tttttggtca cttaataaat
     5761 atcttttagg atttctcttc atttatgcaa caaatccccc gttcgtgtcg gggtttagta
     5821 tgaagggaga taaagaagca catgccactc cctttcacga cagaaagggg gtgaaaagca
     5881 tgaaaccatc ttcttttcaa gaaaccatag aaaatcagtt tgactatatc tgcaaacaag
     5941 ttattgaaga tgaacgaaaa gattacttca aacatctaga cagactatca gcaaaagaag
     6001 tctcgttttc tgatatagat aactaccttg tcaactcttt ttctactgtt gatacgtacg
     6061 tcactgattt ccaactattt aaattatttg gattaagaat caatgttgaa agtgatttat
     6121 taagtgaagc cctgcgtcat ctttcagaga aaaaacggaa cattatttta cttcattact
     6181 ttatggatat gagtgatgtg gagattgcgg agttactaaa tttgaatcgt tcgactgttt
     6241 atcgtcatcg aataagtgga ctagccatga ttaaagaatt catgaaggag tgtaaagaat
     6301 gaaaacagct tatccaaggg ttcccttccc cctcattgta aaggcgacag atggcgacgt
     6361 ggaagcaatt aatcagattg ttaaacatta tcgagggtat acctcaaaac gttcattacg
     6421 tcgcatgaca gacgaatatg gaaattctca tatggttatt gatgaaaccc tacgtggcag
     6481 aatggaaacg aaactcatct ctaagatttt atcgttcgaa attaaatagt cccatttttt
     6541 cgtggaagcg tgtcgaatcg tatccacgct tcccgatttg ggaggtttgt tattccatca
     6601 aagcatattg tgtgttcagt aggttttgat aggctaacaa gccaaacgtt ctttgacaac
     6661 caaataaagg caatcgaata cgtttcggta agaaaagagc tgatgaacta acacgccatg
     6721 acctacaaaa ttagtgagcg attcatgtta gtaattcgaa agtaatcttt agcaggattg
     6781 ctgccatgac tttcttatcg tgataatgat actcccgtat agccatagtc cgagcgttag
     6841 aagcgtcaca ggcaatgggt acggctacat gagaaccatg cagaagtgaa attcctgtga
     6901 gctttgctag agctgttcga ttgctaagat attcttctct tgtcagtgta ttattataaa
     6961 actatttgat ataattatag gtgaatattg gagttttcct agcctataat tgggaaagga
     7021 gtaataatga taacggtcac aaaaaaggat ttagttgagc taggatatgg aacttctttt
     7081 tcagcagaca tcataaaaaa agcaaaagaa ttgatgatta caaaagggca tatctactat
     7141 caatctcgaa agctagatag agtccctcgt gaagctgttg aagaaattct aggaattcgg
     7201 ttttcaaatg aaaacaggtc tgagtagttt ttgcacagta aggagtaaaa actatggtta
     7261 aagacccaat aaaaaaagca aagaatggaa cctattattt tcgtgcaaat ctaggttatg
     7321 attctaaagg gaaaaaaatt caaaaatatc gtagtggatt cactactaaa aaagaagcaa
     7381 gagaagaata ttcgaaactg ctattgatga aaccagaaga attaagtgag aataaggata
     7441 aaatgacgtt taaacattat atctttgaaa ttttccttcc atggtataag acacaggtaa
     7501 agctcagaac atatgaaaat cgcttaccaa ctattaagaa gcatttctct tattttgata
     7561 aaatggctgt ttccgatatt gagcctattg atgtgcaaaa ttggcaacta aaattatcaa
     7621 agaagtgtaa gtcttcttat gtaagagctg ttcaaggact attttcagtt gctatggatc
     7681 gagcaattgt ccttgggata accaccacaa atccatctaa gattattggc aatgtgaaaa
     7741 agcaaaagtc taaaattgaa ttttggacaa aagaagaatt tgaaaaagta atctctctaa
     7801 tttacaaaga agattactat caacactttt tatttatctc tctgtggttt ttatttatga
     7861 ctggaatgcg aattggtgaa gctactgcca ttcaatggga agatattgat tttgactcag
     7921 gagtactaac catcaacaaa acactctatt acaagaatca atcgaattat agatttgttg
     7981 aaccaaaaac aaaggcgagc gttcgtcata ttgtattaga taaatgcaca ttaacttatt
     8041 tatccgaatg gaaggaagta caacaaaatc taattcagac agactttgta atgagctata
     8101 acggtattcc tacccaaaaa catacactat catatgctat tgaacgctat gctaagctgg
     8161 ctggtatcca tcgaatcaga atccatgggt tacggcattc tcatgcttcc ttgttaatca
     8221 gtatgggaga aaatccactt atcattaaag atcgtctagg acacgaagat attgagacga
     8281 ctttaggaac gtatggacat ctttatccta acagtaattt cgaggtagct aacaaattaa
     8341 atggagccat ttcctttaaa gaagcaaaac aaaattatga tacttcacca aagaatcaat
     8401 ttactgtaga ctacttgcga aacaaagaaa tgaaaaaagt gcaataaaag tgcagtaaaa
     8461 agataagaag agccagaaac ccttggtata agaggatttc tagctctcct acaactattc
     8521 ccactccact gttgctggtg gtttagaagt gatgtcatac acgatacggt tgacgtgggc
     8581 tacttcgttt acgatacgta cagagatttt ttgcaagact tcccatggga tacgggcaaa
     8641 gtcagcggtc attccgtcga ttgaagttac agcacggata ccgactgtgt agtcgtaagt
     8701 acgtccgtca cccataacac cgacagagcg gatccctgga agaacagtga aatattgcca
     8761 gatatcacgg tcaagtccag cagctgcgat ttcttcacgc aagatagcat cagattcgcg
     8821 tacgatttct agcttgtctt cagtgatttc gccaagaaca cgaataccaa gaccaggacc
     8881 agggaatggc tgacgccaaa cgattgaatc aggcatgcct aactgagtcc ctaattcacg
     8941 gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat tcaaattgca tatcttctgg
     9001 cagtccacct acattatggt gagatttgat cgtctgtgct gtttctgtac cagattcgat
     9061 aacgtcagta tacaacgttc cttgtgctag gaaagagacg ccttcttcac cagcaagttt
     9121 tgttgcttcg tcatcaaaaa catatacgaa ttcattccca atgattttac gtttttgttc
     9181 tgggtcagat acacctttca acttgtctaa gaagcgatct cttgcatcga ctttgatgat
     9241 gttcaagccg aattttccgc ctagactttc cattacttgt tccgcttcgc ctttgcgtag
     9301 cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg atcgcttttt gtaaaagaac
     9361 cccaacgaca ctagaatcaa cgccacctga aagaccaagc aagacttttt tgtcaccaac
     9421 ttgttcacgg attttttcta cttgcatatc gataaagtta tccattgtcc agttaccttc
     9481 acagtgacaa acatcaaagg caaagtggcg cagcaattcg attccgtatt cggaatgacg
     9541 tacttctgca tggaattgga taccataaaa attacgtgtt gtgtcttgga tagaagcaat
     9601 cggacaatct ttgcttgttc cgactgtttc aaagccttca ggaactttag ttaccaagtc
     9661 accatggctc atccatactg tttgttgttt tggtgtttct ttaaacaaga cagcttgatc
     9721 gcttgttact tctaacaagg ctttcccata ttcgcggttt ttagcaggct ctacggaacc
     9781 gccaagtttg tacgtgatca attgcatacc atagcaaatc cctaatacag gaatacctaa
     9841 attgaagatc tcaggatcga tcccaaatgc attctcatca tatacactgt ttggtccgcc
     9901 agaaagaatg attccctttg gattcatcgc ttttacttct tctgcagtaa tgcggtggct
     9961 caataattcg gaaaagactc caagatcacg aatacgtctt gtgatcaatt ggttatactg
    10021 actaccgtag tctaatacga taatcttttc aacgttcgtc atatcggcaa cgtttgtcaa
    10081 atttattacc cctatccctt taaattttat ctcaaaatag tcaaactatt ttaaaatgct
    10141 aatattttcg catgaaaatc gaatcgatga tatgattttc agttttatgg agaattatat
    10201 cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt tttcaaattc acatttttcc
    10261 atacatcttt tgccatttta aaggcttctt cacgatctcc gatagcaaaa cgataataat
    10321 aattctctgg attttggaaa gccgtatcca gtaacgcacc aaaacgatcc aaataccatt
    10381 tttcgatcag cacgggatcg gcatcgacat agacagaaaa atcaaaaaag tcgctgacgt
    10441 agatttgctg attcgcaggt aattgaagcg tattgatccc ctcaacgatc aagatatcag
    10501 gctgctggat caattcgtac ttgtctggaa tgatatcata cacatcatgt gagtaaacag
    10561 gtacttttat ctcttcctga ccagatttta cacggttcaa gaaatcgatc agcatctcca
    10621 tatcataact ttcaggaaat cctttacggt ccatgattcc acgctctttt aatatacgat
    10681 ttggataaag aaatccgtca gtcgtgatca gctgaacgtt tcttcgtttg aaggtacgag
    10741 acaaaatcgt ctgcagcagt ctggctgttg tactttttcc aacggctaca cttccggcga
    10801 tcccgataat aaaaggcggt acttctacgt atttatgaag aaataaacct ttactcaaga
    10861 acaaagattc aaattctttc atataaagat aaatcagatg agcaagaggt acatagatat
    10921 ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt gatattatct agttcatctt
    10981 gtgtcaaagg tgcttgccca ttacgataaa attctcgcca ttcttctctt gccacacggt
    11041 agtagttcat tggatcattc atattagcct cctgcgttct cccatcaatg gaactatttt
    11101 aacacaaaat aaacgcaaac cccaccactt aagagagatt gccgatcttt ttgtataatc
    11161 tttataatag aaagaaacgg agtcttattc ttgacttgcg cacggataca taaaaggata
    11221 gactgttgtc atgaaagaaa tgagaaggat ggaagacatg acaaatcatt actattctga
    11281 acgcccagat acggcgcacg attttgaaca atgggctttt gagttaaaag gcagaacctt
    11341 tcaatttgta acagattctg gtgtattttc acgtgaaaca gtggattatg gttcacgtgt
    11401 cctgattgat gctttcgatt gggaagagtt acctgatgaa ggaaagatct tagatgtggg
    11461 atgcgggtat ggaccgattg ggttagcttt ggcatttgcg acacagcggt ttgttgaaat
    11521 ggtcgacatt aatgaacgag cggtaagtct agcgcaagga aacgcaaagc gtaaccaaat
    11581 cgaacatgtt gatatccatc aatcgaatat ctatgaagca gttcatgaag aaacctatgc
    11641 agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa gttgtacatg aaattttgac
    11701 aggcgcatat cctcggttga agaagggcgg tacactgaca attgtgatcc agaagaaaca
    11761 aggagcgccg agtgcgcaaa agaaaatgga agaaacattt ggtaatgcag aaatcgtcac
    11821 aaaagataaa ggatattata tcatcaaaag tgtgaaagaa taactagctg aaaaatagtg
    11881 gagcgacgaa agagtggaac tgggcgtgca tgtacgggta cgtatcagtt ctttttttgt
    11941 tgagaagttt ttaaaaacaa agaactattt tttcttcaaa aagaaatagt aggaacagag
    12001 tcgttgtttt ttacgataaa ataaataaga tacagaactt gtatagaagg ctgccaagtc
    12061 ggtagataaa ggaggttttt atcaaaaaac atactttcct tttttctcta ttcttttctt
    12121 gggggttttg gtacactgat agggaattta gatagaaggg agccaatagg atgaagctga
    12181 ccatcagaga tatcgcagaa atggcaggcg tatcagtaac aactgtctca cagattttga
    12241 ataacaaagg aagcagattt agtgataaga caagaaaaaa agtgttgtcg atcgtgaatg
    12301 aacatcatta taagcccgat tatttcgctt caaatgtgat caatcgacat tcaaagacca
    12361 tcggaatgat cgtccctgat gtcactgatt tcttcttctc caaactgatc gaaggtgtag
    12421 agagctattt gaatcctttg ggctatgtga tcatgttatg caattctcgt catagccaag
    12481 aaaatgagat caagtattta caagagcttt cccaccgctc agtggacgga atcttgctgg
    12541 ccacaccaaa tattttacct gagaaatatg cattagacag cggtttttat caaaaaatgc
    12601 caatcatttt aatcgatcgc ggattgaatc gtcgggataa cggacggctt atcgtaaagg
    12661 aatatgaggg cgcctatcaa gctgtttcgc tgtttattga aaatggccat acgaagatcg
    12721 gcatgctgaa ggaaaccact ggatactatc aattagaaga acgtttcaac ggatatcgtc
    12781 atgcgctgaa agatcatggc ctgcctttta atgggaaatt tgttgaacat ggagagttga
    12841 ctgtccaagg tggatatact gcatcaaaaa aattactcaa acataaagat atcacggcta
    12901 ttttttgcgg gaatgatgcc atggcgatcg gatgctatca ggcgatcgat gaattgggca
    12961 aaaaaatccc agaagatatc tcagtcatag gattcgatgg attaaagctg tcagaataca
    13021 tgattccgca attgacgaca gtgcagcagc caagttttga tattggattt tatgctgcac
    13081 gtttcctgat cgatacgatc gaatttcctc aaagaaaagt tccgaacaaa gtgttcgaaa
    13141 caaaattaat tattcgtgag agcgtaaaag tattgacaaa gggctaactc ggcggtatat
    13201 tgcttatgta agcatttaca aaggctagtt agtgcttttt ttatttttag taaaccagtt
    13261 tactaaagtg gtttaccttt cctaaaaata atgtataata ccgaatgaag acaaggagga
    13321 tcaggcaatg cgaatggtgg atctgattga aaaaaagagg gatggaaacg agctgtcgaa
    13381 agaggaaatc gagtacatcg tcacgaacta tacgaatgga aagattccag attatcaagt
    13441 cagtgcatta ttgatggcaa ttttttatca agacatgaca aatgaagaaa tcacgaactt
    13501 aacattggcg attgctaatt ctggtgatgt catcgatttg agttctcttg aaggaataaa
    13561 ggtagataag cattcgacag gtggcgttgg tgacacgacc acattgattt tagcccccct
    13621 agtagctagt gtcggagtga cagtggctaa aatgtctgga cgcggtctag gttacacagg
    13681 tggtacacta gacaagctag aagcaattcc cggatttcag atcgagcttt cggatgaaga
    13741 atttgtacgc attgttaatg aaagtaaagt agcggtaatt ggtcaatcag gaaacttggc
    13801 accggcggac aaaaaattgt atgccttgcg tgacgtcaca gcgaccgttg attctcttcc
    13861 gctgattgcc agttcgatta tgagtaaaaa aatcgcggca ggagcagatg caatcgtttt
    13921 ggatgtgacc actggagacg gtgctttcat gaagaacatc gaagatgcaa gacgtctggc
    13981 aaagaccatg acgagcattg ggaaactggc taaccgagaa acagtggcgg ttatctcaga
    14041 tatgtcagaa cctcttggcg aagcta
//
LOCUS       DAIGUC010000208         9863 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.082, whole genome shotgun sequence.
ACCESSION   DAIGUC010000208 DAIGUC010000000
VERSION     DAIGUC010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.082"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..517
                     /locus_tag="NOB46_002993"
     CDS             <1..517
                     /locus_tag="NOB46_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI1059828.1"
                     /translation="FSSSEPKTDLFFGATNNGRKERAESYKQEFIKRDVTTNYFILPH
                     RGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAH
                     YHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQ
                     YEYDLSSVENK"
     gene            complement(667..1608)
                     /locus_tag="NOB46_002994"
     CDS             complement(667..1608)
                     /locus_tag="NOB46_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI1059829.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1734..2855
                     /locus_tag="NOB46_002995"
     CDS             1734..2855
                     /locus_tag="NOB46_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI1059830.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3113..4615
                     /gene="eat(A)"
                     /locus_tag="NOB46_002996"
     CDS             3113..4615
                     /gene="eat(A)"
                     /locus_tag="NOB46_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI1059831.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4643..5209
                     /locus_tag="NOB46_002997"
     CDS             4643..5209
                     /locus_tag="NOB46_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI1059832.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5420..6481
                     /locus_tag="NOB46_002998"
     CDS             5420..6481
                     /locus_tag="NOB46_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI1059833.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6484..7380
                     /gene="murQ"
                     /locus_tag="NOB46_002999"
     CDS             6484..7380
                     /gene="murQ"
                     /locus_tag="NOB46_002999"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI1059834.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7394..9376
                     /locus_tag="NOB46_003000"
     CDS             7394..9376
                     /locus_tag="NOB46_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI1059835.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9441..>9863)
                     /gene="nrdI"
                     /locus_tag="NOB46_003001"
     CDS             complement(9441..>9863)
                     /gene="nrdI"
                     /locus_tag="NOB46_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI1059836.1"
                     /translation="SGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHENSDFTKETE
                     PFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNKNFNNQYCL
                     TAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         3216 a         1759 c         2151 g         2737 t
ORIGIN      
        1 tttttcttct agcgaaccaa agacggatct attttttggt gcaacgaata atgggagaaa
       61 agaacgagca gaaagctata agcaggaatt tataaaaaga gatgttacga ccaactattt
      121 cattcttcca catcgaggga atgaacaacc tggatatctt acttatgaag agtacctgaa
      181 aaaaacaggg gaatcgcgcg ggattctgga actgttgcgg gagggtcagc aaggagtgac
      241 tttgcggaca tttgaatcca tgtattttca aaagaaacta gtgacggata atcaagcgat
      301 tgctcattat catttttatc gtcctgaaaa tatttttttg cttcgagaac gtgatttaga
      361 tgaattaccg gaatttctgc atacaccatt taagccaatc ctatcagagc tattggaatt
      421 ttatgatgca gaaaattggg caaaacgatt tatcactaac gattccacta tttatgagca
      481 atacgaatat gacctctcct ctgttgaaaa caaataaaaa acctacattt tgaagagatt
      541 atgtactgaa acaaacaagc acaattctta tggcatcatg agagttgtgt tttctttttg
      601 atcttttatt gggcttaaaa aaagagaacc agctgctgat tcagctgatt ctcatcagag
      661 agccttttat tctgcgccaa ggattccttc ttttgcatgg actaattggg tcaaaaaggc
      721 acaatatggt gtagcaatat catatttttg tccttttcgc caaatggcac cattgatgta
      781 gtcgatttca gtcaaacgat ggtttttgat caggtcttgg tacatagatg ggtaatgcaa
      841 cccgatgttg tcaggatcat aagtagaagc aatatgttgg tacacttctt cttgatctag
      901 tatgattcct tcttttgctg cgatagaagc aaattcagat acgattgttc gaaccatgct
      961 ctctgccgct ttttgcgcgc ctagttcagc aatattacaa tccaaaatcg tgcataaacc
     1021 attcaatgtt ccatttacac aagcttttcg ccaaatggaa taacgaacgt tatggctata
     1081 gatcggattt aaatttgctt cttgaaagac ttctacaact ttttttgtaa atgcttcgcc
     1141 ttctggttcc aagttctcta gttcgatttc tccatcacct aacaatgtga cttttccggg
     1201 accagctaga ccagctgtcc acatcgtgat cccaaataag atatttttct ttggcacata
     1261 tttttccagt acatcttcat gacctaatcc atttagtaaa cacaaaacat aagtattgtc
     1321 agtaataatg gattggatcg aacaaaacat atcatctaat tgattggctt ttgttaatgc
     1381 tacgatcaag tccacgtgtt cgttgctttc gatgatttct tctggtgaat agattggcag
     1441 ttttgcgacc acttctttac cgttaaagtc agcaatcaac ccatttgtac gaatggcttc
     1501 aatgtgagca ggccaacgat cgatcaagag gacctcattt ccgctttgat gtagcatcaa
     1561 tccgattcgg ctgcccattg ctccggcccc agctattgcg attttcatgt tttttctctc
     1621 ctttattcaa tgagttccct tttagtatat agaaaaatgg aagaaaatag cattgttttg
     1681 tttgaaaaaa atgaaaaaaa gtgtcttact taagaagaaa gtgagggata cagatggata
     1741 ttttggcggc aattgattca tttaaaggaa gtgcttcttc atttgaacta aatcaggcag
     1801 ttctaaatgg ctgggaagat cgtaaaggaa gaaaaatcaa tgtgccgatt gcagatggcg
     1861 gagaaaatac tgcagaagca atctattacg cgctcagggg aacatggcgt accattgatg
     1921 ggatggatct cttattccgt cagcgaaaaa tcagctattt attgacaact tggcaaggaa
     1981 aaaacaccgc agtcatcgaa tctgcacaag cattggggtt agatctactt gataaaccaa
     2041 cggatcaaac tatccgactt gcttccagtt atgccttagg agaacttatt aaagatgcac
     2101 tgcttcaaga agtagaacaa attattgtca ctttaggagg aagcgggtgt agcgatggtg
     2161 gtctaggatt actccaatcc ttgggtgctt ctttagaagg gtacacagaa ggaaatcctt
     2221 tattatctac taaaaaactt cattttgatc gaagaaacgt tcttgtttct aaagtaaaat
     2281 tgattatcgc tgcagatgtt accaatccat atacaggtca acaaggagct gcttggcaat
     2341 ttggaagaca aaaaggagga atagatacga cgctagcttt cttagataaa caagcaggaa
     2401 agattgctca gcaaataaaa gatttctggg aggtggattt agatgatatt ccaggaagtg
     2461 gagcagcagg cggtattggt ggagcccttt ttttgttggg agcgaagatg gtttctggtt
     2521 tcgatttagt cagccaaatc actggattgg aaaaaaagat cgaacaagca gatgtcatca
     2581 ttacaggaga agggcggatc gatcagcaaa cgatccacgg aaaagttcca tacggtgtag
     2641 cagtgcttgc aaaaaaatat cgaaaaccaa taatcgctat ttgcggaagt agagaccaag
     2701 agctagaagg actttctgat tttctcccaa ttgtcttaag tattcatttg ggtccaatag
     2761 gtttagaaga agcaatggaa cacaggcaaa cattagaaaa aacaaaaatc ttaggacaga
     2821 cacttagcag atttttcacc atcctcccga agtagttgac aaaatcattt tctttatgct
     2881 atcgtaattt caaatatagg acaaagtgag ggatccgtgc attgaaaaat taagtcgatt
     2941 gatgaaagct gcattcagac tgtaccttgt ggagacaagg aagcagtgtg cagattttcg
     3001 ggattggctt ggttttttcg atgtatgggt ctttttgtgt gtatccaacc cttgcatcct
     3061 ctttagccag ttctgaaaat aggactggtc tttttttacg aggtgatgga aaatgtctaa
     3121 aatcgaaata aaaaatctga cattcggcta cgacagccaa ggcacattat tatttgaaca
     3181 agcaaatcta aattttgaca cacaatggaa actaggactt atcggacgaa acggtcgagg
     3241 aaagacaact ttactgaata ttctacaaaa caaactacct tatcaagggc aagtaatcca
     3301 tcagcaagaa tttgcctatt tcccgcaaca gacaaaagat aaagaacgtt taacctatta
     3361 cgtgttaaat gatattacgg attttgagat atgggaaatc gaaagagagc tccaattgat
     3421 gcaaacagat cctgaaatct tatggagaga attcagcaca ctatcggggg gagagaagac
     3481 aaaagtccta ctggcacttt tatttgtgga tgacactcat ttcccgttaa tcgatgaacc
     3541 aacgaatcat ttggatatct ctggtagaaa acaagtagcg gcttatttga aaaagaaaaa
     3601 acaaggcttc atcgtggtca gccatgaccg gggatttatc gatgaagtag tggaccatgt
     3661 tttagcaatc gaaaaaagtc aactggaact ttatcaaggg aatttctcta tctatgaaga
     3721 acagaaaaaa cttcgtgatg aatttgaaat ggctcaaaat gaaaaattga aaaaagaagt
     3781 cagtaggcta aagaaaacag cagctgaaaa agccgaatgg tctcgttccc gagaaggaga
     3841 taaaacaaag aaacaagtcg gattcatcga tactgaatct agacgagtga ataaaggagc
     3901 agtgggtgct gatgctgcac ggacgatgaa acgatccaaa gcaatcgtga atcggatgga
     3961 gacccagatc agcgagaaag aaaaactatt aaaagatatc gaatatatcg attctttgac
     4021 gatgaatagc caagcgtctc accataagcg acttttaagc gtagaagatc ttcaattagg
     4081 gtatgaaaat ctgttattcg agccaattca ttttacaatc gagcctcatc agcgggtggc
     4141 gatttcaggt cctaacggtg caggaaagtc atccattatc cattatcttc tgggggcatt
     4201 caacggcaag gttataggag aaaaatacca gccaaaacat ctgagcatta gttatgcaag
     4261 ccaaaattat gaagacaatc gaggaacgtt ggcggaattt gcagagaaaa accaagtaga
     4321 ctaccaagca tttttgaaca acctccgaaa gcttgggatg gaaagagatg tttttcataa
     4381 caagatcgag cagatgagta tgggccaacg gaaaaaagtg gaattggcta aatctttatc
     4441 acagccagct gaactatata catgggatga accattgaat tatttggatg tcttcaatca
     4501 agaacaatta gaacaactga tcttgaacgt gaaacctgcc atgttactag tggaacatga
     4561 tcaaaccttc ctggataaag tatctactga gattatttct cttgagagaa tctaaccctt
     4621 gtaatctcaa gaacaacaag gtatggttaa ggggaacttt gccaacgaag gagagaatca
     4681 catgctttat gtaacgagac acggagaaac aacttggaac gcacaaggat tagtttgcgg
     4741 acgggcagat gtgccgctga ctgaaaaagg acagatgcag gcacagaaac tagcagaaaa
     4801 ggtagtagat ttgcctgttc caatcacgaa aatcatccat tcccctcttc aacgagcaag
     4861 agatacagca caagcagttg ctgatcgtct cagcttgccg ctgaccgttg atgaacgatt
     4921 ggtagaaatg gattttgggg attatgatgg actgccaagc aaagatgaga actttcaaaa
     4981 agcacgttta gcgttcgctg tacgattccc aaatggggag tcagtcttag atgtgtatgc
     5041 acggatcgtt cctttattga aagaatgcat cgaagacgaa gaaaatgtct atctgttagt
     5101 ttgccataat gccttgataa gagtgatcaa tgcttatttt catccgatgc ctaatgaggg
     5161 gttctttaca ttcatggtag ataatacaga attggtttct tatgagtaat tatgtttttg
     5221 tgttatttaa ataaaatatt tcaaggcact gcttttgctt agcagtgcct tttttaggtt
     5281 atgacaattc ttttgataat ataaactcaa cctttagaaa tgaaatttaa ttattttaat
     5341 aaaagtattg aaattttgtt tctttagata tatactctag tcatagaaat gaagacggat
     5401 acagaaaaag agggataata tgtttggctt ttcaatattt atgaacgatt ctttgtcaga
     5461 agagaagaaa cagtatatcc gccaaatggc atccaatggc tttgtcggta ttttcacttc
     5521 catgcatata ccagaagatg atgtttcggc atatcaaaag cgattgatcg aactaggaag
     5581 cgaagcgaaa aagaataaac tagaattgat ggtcgatatt tcaggagagg cattggaacg
     5641 agcgggtttt tcattagaag atctaacgcc tttgaaagca attggtgtaa caggtttaag
     5701 aatggattat catatttcca atcagcagat tgccgactgg tcacatcaat tgaaaatcag
     5761 tttgaatgct agcacgatca cgcctaaaga tatcgatgaa ttgaaagaag cagaagctga
     5821 tttctcacag attgaagctt ggcataatta ttatccacgt cccgaaacag ggctggacaa
     5881 agaatggtat cagaaaaaaa atcaatggct caaaattcaa ggtctccttg tccaaggttt
     5941 tgtaccagga gatacagagt tgagaggccc actatatcaa ggattgccaa ctttggaaga
     6001 acatcgaggg atccatcctc ttgcaggcgc tctagatcta ttagcaagta acacggatat
     6061 tgtttacatc ggagatgcag gtctgtcaga aaacgttcag gagcaatttg cttctttcca
     6121 aaaagaacag acagtcttgc tccatacgga acctgtagat gaagaatttt acgaatatat
     6181 attagggaag catacgaatc ggcaagacga tgcaagagat gtcatacgaa gcgtagatgc
     6241 acgttttcga gagattccgc ctatcccagc aagaaataca gctacgcgta tgaaagggtc
     6301 tattacttta gataacgaaa agtatttgcg ctatatgggt gagatccaat taaccaaata
     6361 tgatttgcca gcggatgaaa aagtgaatgt agtagctaaa gttatcaaag aagagctacc
     6421 attgatcaac caaatcaaag ctggtatgaa ctatcaattt ataagaaaag aaggaagata
     6481 aaaatgagca aaatcaattt agagaaccta acaacggaac gcagaaacca agaaactttt
     6541 ggattagatg agatgagtat ttctcaagcc gttcaactaa tgaacaaaga agatcagaaa
     6601 gtggccgctg cggttgaaaa agaactgaca agtatcgaac cagtgattgc taacacgatt
     6661 gagtccttta aaaaaggtgg acgtctgatt tatatgggag ccggaacaag tggaagacta
     6721 ggtgtgttag atgctgctga atgcgtaccg acattcggtg tagaaccgga aatggtcata
     6781 ggtctaattg ctggtggaga agaagcaatg actgtagctg tcgaaggggc cgaagattct
     6841 tatgagctag ggcaagaaga tctaatcaag ctgaatttga caaaaaatga tatagttatt
     6901 ggtatcgcag ctagcggtcg tacaccatat gtgatcggtg gattagatta cgcaaaatcg
     6961 atcggtgctg tcacaggaac gatttcttgc aataaacaag ccgaaatcag taaacacgcg
     7021 gatttcccaa tcgaagtcga tgcaggtcca gaatttttga caggctctac tcgattgaag
     7081 tcaggaacag cacaaaaact tatcttgaat atgatttcta ctatcagtat gattggtata
     7141 ggtaaagtat tcaataactt gatggtcgat gtcaaaccaa caaatgaaaa actaatcgaa
     7201 cgctcaaaac gaatcatcat gcaagcgaca gaagctgatt acgaaacagc tgaaaagtac
     7261 tttgaagaag cagatcaaaa tgttaagctg gctatcgtca tgattttgac aaatagtgat
     7321 aaagaggaag ctcaagcaaa attagctgaa gcaaacggat ttgtaaaagg gaccttatga
     7381 gggggaaaag accatggcaa aaaacgaact gactttggaa gaactggcaa aacaaattta
     7441 taaaggggca ggcggcatgg gcaatgtaga aagcattgtc cactgcatga ctcgtgtgcg
     7501 tatgaagatc atcaatgatg atcttgtaaa tgtctctgaa ttaaaagcga ttccaggagt
     7561 gcttggtgta gtagaagatg aacagcttca agtcatcatc ggacctggga aagtgaacaa
     7621 agtagcacag caaatggttg atttggcagg cgtgaaatta ggagaaaaac tttcttctgt
     7681 aagtacagct acagcaaatt catcagcatc tggaaaagac cgtgtaaacg aacgggcaca
     7741 agaaatgaaa gcggcacaaa aatcgaaaca aaaaccatct aaaatcaaat cggtattaaa
     7801 agacatttct aatatctttg tgccaatgat tcctgcattt gtcggtactg ggatcgtggc
     7861 agggattgcc gcagttttag caaacttagt cacagccgga acacttgatg cagcaacatg
     7921 gcaacaatat atcgatgtga tgaacatctt gaaaaacggg atgtttagct acctagttat
     7981 ctatacaggt atcaatgctg cacaagtttt tggtgcaaca ccaactcttg gtggagttat
     8041 cggggccgtt gtgatgctga cagggatgaa tccggaagca ccactgaaaa acttatttac
     8101 tggtgaagct cttgcagctg gacaaggtgg gatcctaggt gtcatcttcg ctgtttggct
     8161 attgtcaatc gttgagaaaa aactgcataa agtagtacct gatgcggtag atatcatcgt
     8221 tacaccaact ctttcattga ttgccatcgg tctgattgaa attttcttca tcatgccttt
     8281 agcaggtttc atttctgatg gcatggtcgg tgggatcaac tgggtacttg gcgttggtgg
     8341 agcatttgcc ggcttcgttc taggcacatt attcttgccg atggttatgt tcggactgca
     8401 tcaaattttg actccaatcc atgtgcaaat gattgatgaa actggtcgta cgctattgct
     8461 tccaattctt gcgatggctg gtgcaggaca agtgggtgca gcattggcat tatggattcg
     8521 ctgcaaaaaa gataaagaat taacagaaat gatcaaagga gctttaccag tcgggatcct
     8581 aggaatcggc gaaccattga tttacggagt aacattacct ctaggacgcc catttattac
     8641 tgcttgtatc ggtggaggta tcggcggggc agtgatcgga atgatcggaa atgtcggggc
     8701 tatcgctatt ggaccttcag gagccgcttt gatcccattg atctctgacg gtaaatggtt
     8761 aggctacatc cttggattat tggcagctta tgctggtggc ttcgttgcta cattcttctt
     8821 cggtattcct aaagaccgtt tagaaaaaga agaattagcg actgaaacag ccacagtaaa
     8881 tgaagtgcct gaaaaagtag tacctcaaac ttcagctgaa agtgtgacta tcctctcatc
     8941 agttgctgac ggaacagttg tttctttaga taaagcaagt gatccagttt ttgcacaaaa
     9001 gatgatgggt gaaggctact ttgtagaacc agaaaacgga catatctatt ctccagttac
     9061 tggggtagtc agctctgtct tcccaacgaa acacgctatt gggatcacaa cgccaaatgg
     9121 tttagaaatc ttgcttcata tgggaatcaa cacagttgac ttaggcggta cgccatttga
     9181 tgtgaaagta acagaagggc agcaagtgac acctgatacg cttgtagcag aagctgactt
     9241 agaagcgatc aaagcagcag gcaaagaaac atccatgatc gtcttggtaa ccaatatgga
     9301 tcgtgtaaaa aactttgtct tggaaaaaac aggtaaagca aaagcaaaag cacctgtgat
     9361 ggatgtcaaa gcttaatatg atagaaacaa tagaaacgaa agaagaaact gaaatctatt
     9421 tttcagcttc ttctttttta ttatttattg ttttctgcta aaatctgata aattcgtgtc
     9481 acatcagatg gtgttccccg taattcataa tctgccaaga aaggaaagcc aaatgtttgt
     9541 gcatattgtt tggctgttag acaatactga ttattgaagt ttttatttcc gctaccgact
     9601 acaccaagac aaagtttatg attgtcttca tgttccagat attcacgcat cgtttcggtc
     9661 aagatttctg tatcaccgtt atctaaacca tttccgccgt ctaaataagt aggaacgaaa
     9721 gtaaaaaatg gttctgtttc tttcgtaaaa tcactatttt catggatttc ttttaaagta
     9781 acttcaggat tgacaggatc ttctgcatgc attttttcag catattctgc tagatgtttg
     9841 gcaaaggcac gcgtatttcc tga
//
LOCUS       DAIGUC010000209         7780 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.089, whole genome shotgun sequence.
ACCESSION   DAIGUC010000209 DAIGUC010000000
VERSION     DAIGUC010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.089"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            245..1213
                     /locus_tag="NOB46_003002"
     CDS             245..1213
                     /locus_tag="NOB46_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI1059837.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="NOB46_003003"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="NOB46_003003"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI1059838.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="NOB46_003004"
     CDS             2243..2851
                     /locus_tag="NOB46_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI1059839.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3279..4190
                     /gene="vanY"
                     /locus_tag="NOB46_003005"
     CDS             3279..4190
                     /gene="vanY"
                     /locus_tag="NOB46_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCI1059840.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4343..4828
                     /gene="vanZ"
                     /locus_tag="NOB46_003006"
     CDS             4343..4828
                     /gene="vanZ"
                     /locus_tag="NOB46_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI1059841.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5115..5444)
                     /locus_tag="NOB46_003007"
     CDS             complement(5115..5444)
                     /locus_tag="NOB46_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI1059842.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5749..6078
                     /locus_tag="NOB46_003008"
     CDS             5749..6078
                     /locus_tag="NOB46_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI1059843.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6068..6355
                     /locus_tag="NOB46_003009"
     CDS             6068..6355
                     /locus_tag="NOB46_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI1059844.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6634..7197)
                     /locus_tag="NOB46_003010"
     CDS             complement(6634..7197)
                     /locus_tag="NOB46_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI1059845.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2566 a         1297 c         1546 g         2371 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
     2941 atagtagata gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc
     3001 tgcggcaaga tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc
     3061 cattgtcaac aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc
     3121 atctacattg gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg
     3181 gcaaaacggc acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt
     3241 tcatacttcc aactatatag ttaaggagga gactgaaaat gaagaagttg ttttttttat
     3301 tgttattgtt attcttaata tacttaggtt atgactacgt taatgaagca ctgttttctc
     3361 aggaaaaagt cgaatttcaa aattatgatc aaaatcccaa agaacattta gaaaatagtg
     3421 ggacttctga aaatacccaa gagaaaacaa ttacagaaga acaggtttat caaggaaatc
     3481 tgctattaat caatagtaaa tatcctgttc gccaagaaag tgtgaagtca gatatcgtga
     3541 atttatctaa acatgacgaa ttaataaatg gatacgggtt gcttgatagt aatatttata
     3601 tgtcaaaaga aatagcacaa aaattttcag agatggtcaa tgatgctgta aagggtggcg
     3661 ttagtcattt tattattaat agtggctatc gagactttga tgagcaaagt gtgctttacc
     3721 aagaaatggg ggctgagtat gccttaccag caggttatag tgagcataat tcaggtttat
     3781 cactagatgt aggatcaagc ttgacgaaaa tggaacgagc ccctgaagga aagtggatag
     3841 aagaaaatgc ttggaaatac gggttcattt tacgttatcc agaggacaaa acagagttaa
     3901 caggaattca atatgaacta tggcatattc gctatgttgg tttaccacat agtgcgatta
     3961 tgaaagaaaa gaatttcgtt ctcgaggaat atatggatta cctaaaagaa gaaaaaacca
     4021 tttctgttag tgtaaatggg gaaaaatatg agatctttta ttatcctgtt actaaaaata
     4081 ccaccattca tgtgccgact aatcttcgtt atgagatatc aggaaacaat atagacggtg
     4141 taattgtgac agtgtttccc ggatcaacac atactaattc aaggaggtaa ggatggcgga
     4201 atgaaaccaa cgaaattaat gaacagcatt attgtactag cacttttggg gtaacgttag
     4261 ctttttaatt taaaacccac gttaactagg acattgctat actaatgata caacttaaac
     4321 aaaagaatta gaggaaatta tattgggaaa aatattatct agaggattgc tagctttata
     4381 tttagtgaca ctaatctggt tagtgttatt caaattacaa tacaatattt tatcagtatt
     4441 taattatcat caaagaagtc ttaacttgac tccatttact gctactggga atttcagaga
     4501 gatgatagat aatgttataa tctttattcc atttggcttg cttttgaatg tcaattttaa
     4561 agaaatcgga tttttaccta agtttgcttt tgtactggtt ttaagtctta cttttgaaat
     4621 aattcaattt atcttcgcta ttggagcgac agacataaca gatgtaatta caaatactgt
     4681 tggaggcttt cttggactga aattatatgg tttaagcaat aagcatatga atcaaaaaaa
     4741 attagacaga gttattattt ttgtaggtat acttttgctc gtattattgc tcgtttaccg
     4801 tacccattta agaataaatt acgtgtaaga tgtctaaatc aagcaatctg atctttcata
     4861 cacataaaga tattgaatga attggattag atggaaaacg ggatgtgggg aaactcgccc
     4921 gtaggtgtga agtgagggga aaaccggtga taaagtaaaa agcttaccta acactatagt
     4981 aacaaagaaa gcccaattat caattttagt gctgaggaat tggtctcttt aataaatttc
     5041 cttaacgttg taaatccgca ttttcctgac ggtaccccca aactaagatt tcatagatag
     5101 attttctgat aactttaaaa aacacgaata gcggaaagga tgtcttcatt cgctaaagag
     5161 taataaacta cttttccatc ttgacgtgat tttgccattc catgtttttt taaaaaacgt
     5221 aaatggtgtg acgttgtagc gacactagca gtaagtattt ctgctaaatc acagacgcac
     5281 atttccttat aggtttctaa agcatagaaa attttaattc tagaaaaatc gctgaaacat
     5341 ttccctaaca caagtaagtt tgaaaaatct ttttgatcca atttattttt tattccattt
     5401 actttttctt tatgtacgac agtcacttgg caaacttttt tcattcatct cacctcacat
     5461 tcaaacgatt atttgaatga agtataccta tttgatcact cttttgtcaa tctaccttaa
     5521 ttccaataca ctattataag caatttcatg tattgaagta aacttacttg caagtgcgtt
     5581 tttgattcca agttaaaaac atattattat tctacataat ttcctaatca aataaaactc
     5641 ctttgaaaat tgttctaaag gagttttatt attttgtatt tctactaaaa atagcgtaca
     5701 atgtaattac taagtaatta cgaaatgtaa aataatggag gaaataatat gattacaaaa
     5761 acaagaaaac aaggaaattc tattatgtta acggtcccta aagaattcga tgtgcccaat
     5821 ggtgttgaag tagaagctaa gcttgtagag aatggtatcc tttatgagtt tgtagagcct
     5881 aaaaaagaat tttttgattt tagtgaagat attttggctg atattctttc agaaggttat
     5941 agcaaacaag agatcttaaa agaatttaga aatagaaaaa atgcgttaac ttctgcattt
     6001 aaatctattg ctgaagatac tgttgcaaat tctaaaccga tgacaaaaga ggagttggca
     6061 gcagaaattg gcttatgaga ttctaccttc taaacacgta ataaagtatc taaaaaaatt
     6121 aaaagagaaa acattaaaag aacaattttt aacgataatt tatgatgaga tagcagttcg
     6181 tcctcattcg ggagaacaaa aaacgggtga tttatcagga atttgggcta ttggattcaa
     6241 gtatgcaggt acgacatatc gcgttgcata tgaaattaaa gataatgcag tgatacctat
     6301 cttactatgt ggaacgcatg aaaattttta tgaacaatta aaaaagatta ggtaagaacc
     6361 caatgtttca acttgagagg atagacgaca ctttaaaaga taatttttaa cagctgagag
     6421 ttgtaatacc ctataatttt aaaccactaa cctatatatt tatgaaaaat agaaaaaatt
     6481 aaaacgcatt ttaagcctct ttcaaattaa aagcttcatc cttatgcaca aagagggctt
     6541 aaaatgcgtt attttatatt gttttttagt aataataaaa aaatcactct aattctccca
     6601 taaatattat agattcctaa agattaaaat agattattcc ctattgtctt ttaagtagcg
     6661 gtagagtgtt gccttgctaa taccagtcat ttccgtaatt tcttttacgc tataaacctg
     6721 acttttatac aattttactg ctcgatcaac atctttctgg ttcactcgtg gacggccacc
     6781 tttacgacct ctcgcacgtg cacttttcaa accttctttg gtacgttcaa caattaaatc
     6841 acgttcgaac tgactaaatg cttggaagac agtcatcatt aagcgtccgt gaggcgtgct
     6901 ggtatcgaag ttttctttca agctcaccag cttaacatgg tgttcttcaa aataggtaac
     6961 aaggtcaatc aaatcctttg tactacgacc caatcgagaa aaactttcta caattaccgt
     7021 atctcccgga cgaattttat cttttaaacg atttagttgg ggacgaaccg ctttggttcc
     7081 cgtcattttc tcagttagga tttcattaca attttgttca ttgagtaagt ctaattgacg
     7141 atttagttct tgtgaacgtg tactcactcg ggcataacca taaatgtatc cactcatgct
     7201 tttcttcctt tcgtacttta attctggctt gattgtatca taaaagggag ttatagatac
     7261 atagttaatg caacaagtta tgatacaaaa tatgacctct tttatttaat aaaagaggtc
     7321 atttcatttt gtctcataat cgattgtttt tgatacgagt gtgtatacga aataaacaaa
     7381 aaaatcttaa gtaaatttct agatacctaa tttaatccta actagtgtat cctaaagtta
     7441 ataacgagtt tatcacaatg aaaattataa aatgctccca tattagatat aacatgcaat
     7501 atttgaatta gaactacaaa atttattcgt tttataaagt aaataatgtt gagatactaa
     7561 ggaatagaat attataagga attgagctga atgtattgga taaaaaaaga ataactttat
     7621 tagagatgga ctataaaaat gctcgtaatt ttcttctgaa gtctgaaagc tatttgaatg
     7681 ctcagctacc agaatatatt agttttgacg aaactttaaa atctgctaaa aaagttttaa
     7741 cttcgccgtt tgtataatta agcgagacaa ataaaaaagc
//
LOCUS       DAIGUC010000210         6319 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.100, whole genome shotgun sequence.
ACCESSION   DAIGUC010000210 DAIGUC010000000
VERSION     DAIGUC010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.100"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            11..2458
                     /locus_tag="NOB46_003011"
     CDS             11..2458
                     /locus_tag="NOB46_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI1059846.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            2688..3755
                     /gene="rlmN"
                     /locus_tag="NOB46_003012"
     CDS             2688..3755
                     /gene="rlmN"
                     /locus_tag="NOB46_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI1059847.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(3948..5051)
                     /locus_tag="NOB46_003013"
     CDS             complement(3948..5051)
                     /locus_tag="NOB46_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI1059848.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            5604..6152
                     /gene="aac(6')"
                     /locus_tag="NOB46_003014"
     CDS             5604..6152
                     /gene="aac(6')"
                     /locus_tag="NOB46_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI1059849.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2102 a         1088 c         1364 g         1765 t
ORIGIN      
        1 gggataataa atggcacaaa agaaacggcc tactaaaaaa aggaaaaaga cgaaaaaaac
       61 gaaaaagcaa aaacagcagc aggaacaaat gctgacgatt ggtgttgggt ttgccttgat
      121 tttatttgct gtcttcggct ttttaaaatt aggtttttta ggaatattga ttgcaaacgg
      181 ctttcggatc attgcaggaa atacttacca aatcctctgt cttttattag ccgtattagg
      241 attttggatt gtcattaaga atacagagtt ttcaattggt aaaaaccgac gctggtttgg
      301 cggcatactc ttttatttcg gtatcttatt attgttacat gcccatttat ttggcaaact
      361 ccatactggg gaaccaaata tcatggggac gacatgggat ttgttagcca gtgatataaa
      421 acaaagtcaa gtagacaata acgttggtgg tgggatgatt ggagcaatcc tttatcattt
      481 tacttacttc ttgattgcac agcctggaag ttatttagca gcagtgctat tactggcagg
      541 aggagcattc ctgttcagta atctggaagg ctatcagctg ttaaatggta tccaatcaat
      601 tggagaacga gtacaggaat tattggaagg tgatcctgcc aagcaagctc gaaagcaagc
      661 ggcaaaggaa gagagaatga aacagcgcgc agaagcgaaa gaagcaaggc gcttagctgc
      721 aaaagaagct gcagaaaaag aagctgcaga atatgagaag aaaaaagcgg tgagccagca
      781 aagggaaaat actgctgatg aatggcagga accagaaaat acagagccgg agcagctaag
      841 ttttgttcca atcgacagtt ttcaagaaaa tatccatcct gcgaatctag agaaaccagt
      901 accagataca ccaaaacaga ccaatacagc agaaggtttt tcagatgagt tgccagagga
      961 tgacggtacc tcattagaat ttgagattga agcagaacag gaaaatcaag actatgaatt
     1021 accgacagtt gatttgcttg attctatacc aactgtggat caaagtgatg agtataaaaa
     1081 aattgaaaaa aatatcggcg tattagaaca aactttccaa agtttcggtg tcgatgccaa
     1141 ggtcgtcaaa gccagcttag gaccatccgt cacaaaattc gaagtccagc cggctgtagg
     1201 ggtaaaagta agtaaaattg tgaacttaac agatgatatc gcgcttgctt tagcggcgaa
     1261 agatgtccgg atggaagcac cgattccagg taaatcactg attggtattg aagtaccaaa
     1321 tggaaagatc agtatggttt cctttagaga aatcatcgaa gcacaaccaa accacccaga
     1381 taaattacta gaagtacctt taggacgtga tgtttctgga cgggtacaaa cggctgatct
     1441 ttcgaagatg cctcacttac tcgtggctgg ttcgactggt agtgggaagt cagtagcaat
     1501 taatgggatt atcacaagta tattaatgcg tgctaagccc catgaagtaa aactgatgat
     1561 gatcgatccg aaaatggttg aattgaatat gtacaacggc atacctcatc tgttgacgcc
     1621 ggtcgtgacg aaccctagaa aagcagcgca agccttacaa aaagtagtac aagaaatgga
     1681 agaacgatat gaaaaattcg cggcaaccgg agtaagaaat atttctggtt acaatgaatt
     1741 tgttcaacag aaaaacttgg aaaacggaac gaaacatcca accttaccat tcatcgtagt
     1801 gatcgtagat gaattagctg atttgatgat ggtagccagc aatgaagttg aagatgcgat
     1861 tattcgttta gcgcaaatgg ctcgggcagc ggggattcat atgatcctag ctactcaacg
     1921 tccaagtgtg gatgttatca caggaatcat caaagcaaat gtaccttcca gaatggcatt
     1981 tgcggtatca agcggtacag attctcggac gatcattgat tctaatgggg cagaaaagct
     2041 cttagggcga ggagatatgc tattcttgcc aatgggtgag aataaaccga tccgtgtgca
     2101 aggagcattc atttctgacc acgaagtaga acgggtcgtt caatttgtta cagatcagca
     2161 agaagctcat tatgaagaga aaatgatgcc gacagatgaa gttgaaacga caggtgctcc
     2221 agaacagcca caagatgagc tgtttgaaga agcaaaagca cttgtcgttg aaatgcaaac
     2281 ggcaagtatt tcccttctcc aaagaagatt tcggatcggt tacaaccgag cagcacgttt
     2341 agtagatgaa ctggaagctc atggagttgt tggcccgtca gaaggaagca agcctcggaa
     2401 agtattcatt gagcaggaag aaacatcaga aacgttgccg gacgataatg acatgtaaaa
     2461 cttgtgtgat gaagggttga aaaacgaata accaataaaa agacaaggca tgatgatacc
     2521 aaaagaaaaa atggtttttt tccatctttt ctaatacggt atgatgtctt gtctttttag
     2581 tttttgtgag attaaagttc tattcgattt atttgtgaag tattgcatta aggaaatgaa
     2641 tcatgtatag tatgtagcga aactttgaga aaaagaggga aaatactttg gaaaaacagt
     2701 ccatttatgg cttgacgaat gaagaattaa tcaattggtt tatagaaaac ggcgagaaaa
     2761 aattccgagc tgcccaagtt tgggaatggt tgtatcaaaa acgtgtaagt aatttcacag
     2821 aaatgacgaa tctatcgaaa caattgatcg aaaaattatc ggagcatttt atcatcaatc
     2881 ctctaaaaca gatggtcgtc caagaagctt cggatggtac agtaaaatat ttgtttgaac
     2941 tccctgataa aaacatgatt gagactgtac tgatgagaca agaatatggc ttgtcagttt
     3001 gtgtgacgac acaagtagga tgtaatatcg gctgtacgtt ttgtgcaagc gggctgctca
     3061 aaaagaaccg tgatctgact gctggagaaa ttgttgcaca gatcatgatg gtccaacatt
     3121 attttgatga gcgcaatctt ggcgaacgcg tttcacatgt cgttgtaatg gggatcggtg
     3181 agccatttga taattacgac aatgtaatgg actttttgca tatcatcaat gatgccaaag
     3241 gattggcaat tggtgctcgg cacattacag tttccactag tggattagca cacaaaatca
     3301 aggaattcgc taataacggc ttgcaagtca atctggctat ttccttgcac gcgccgaata
     3361 atgaggtgcg aacatcgatc atgcggatca accgaagttt cccaattgag aaattgatgg
     3421 aagctgtgga tgagtattta gagaaaacaa accgtcgaat cacgtttgaa tatatcatgt
     3481 tgaatcaagt aaatgataga ccagagcatg cgcaacaatt agcagatcta ttaaaagata
     3541 agaaaaaatt agcatatgtc aacttgattc catataatcc agtcagtgaa catgatcaat
     3601 attctcgcag tccaaaagct gatgtattga gattttatga tgtattgaag aaaaacggcg
     3661 taaactgtgt gatacgtaaa gaacatggta cagatattga tgcagcttgc ggacaattgc
     3721 gaagcaagca aatgaaaaaa acagttgcca aataatcgta tcctactcgt tttttcaatt
     3781 accataaaag gagcagtttt cttaattaag gaactgttca acttaaataa gagaaaagat
     3841 tctatagcga aagctataaa gctttttttg acaagaaaaa ccctcatcaa gcaaagaaat
     3901 gtcctcaatt tgatgacagc ctgcttgatg ggggttttag caattattta actgattttc
     3961 ttatatcctt gctggctttc ttgtgtagca tgataagttt ctacgtcaag aatggcctgt
     4021 ttaaattttt ctcgggtgat ttcataaggc acatgtttaa tatcatttgt tgccatggct
     4081 ttatctaaga ttgcttctaa atcggtcgtg acattgagat tcatgtcggt taacgatact
     4141 ggaagttggt tctttttcat aaacacatag attttatcaa acaaatcgaa ctgctgatcc
     4201 atcatcaata aggtcagtac accataactg acagatgctc cgtgaaggta tccctccatt
     4261 ttttctagaa cagtcgtacc gtaatagaat gagtgtgcca tagcagaatt atagttattg
     4321 ttaactaaaa cagaaaccaa tccggtagta acaatgatat ccgaaacgac ttgttcaatt
     4381 gcatatgagg gacgatcgtc ggcactatct ttcaatgctt gcgtaccata agtcaagaga
     4441 cgatcaatgc acatttttcc gatttggatt cctaatctat ccgtgtagcc tagatcatcg
     4501 ccacgagcag aaaaagtaga ttcgacttct ttggataaag catcgccaat acctgcccat
     4561 aagtatttat caggtgcttc ggcaataatt gctgtatcaa tgaaggtgtg tacaggtggt
     4621 tttgaaggaa agaagagtcc gtccattacg ccttcttcgt tatagatgac acataccgca
     4681 gtgacgggcg aacagttcga accaatagtg ggaaaggtga agactggttt agctagtttt
     4741 tcaccaatga cttttacagt atcgcaagca cggccaccac cgactgcaaa caggacgtct
     4801 gctttttgga cactttcatg ctggatcaac tgttcaatat ttccataagt tgaattaccc
     4861 ccgtaccaga gactggcgac aacctctatt tcctgtgtca aagctacttt tattttgttt
     4921 tctgcctttg aaagtgcagt cttccctcca atcagcacta cttttgtccc atattctttg
     4981 acgattccat ttgctttttc atacgcatct gttccaatgg tataatttgg taagaaaaca
     5041 ctttgactca tattcatttc cttctttctt cgttgaaacg ggttaaaatt ttaaagagtg
     5101 atcgatctga ctgcggctgt agatggagta gaggtgaacc taagacagga taagtgatga
     5161 ataaggtggc atgaacacct tgaaatcatc aataagtatc ctaaaaacga acaagtacaa
     5221 aaacattgaa aacgacaata atgaattttt gttcctctta gtatttctac cgattccctt
     5281 tgcttttttg taattatcta aaaattctaa aaattaagat tattatatga aaacaggttt
     5341 tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat catgatgaac
     5401 aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt gaataaagtg
     5461 tttctgtata atttttttat tttataagta agataaataa tgaaagaata gagatactga
     5521 ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac tgttagaata
     5581 agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat aatccagtat
     5641 tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat ggagacagct
     5701 cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca gcggtagacc
     5761 aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca ggttgggaat
     5821 tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact cgattagtca
     5881 attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta ggtacggatg
     5941 atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca tttgataaag
     6001 tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa ttaggttata
     6061 aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt tggatggcaa
     6121 aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca gaagtaatca
     6181 gcttcaagaa ataagaagga atttacgaaa attacttctt gaatttttgt gaaattccaa
     6241 cttatttccg aagaagctac ttttggaaca ccgtgtacca gaggttgtga aaaagtcgct
     6301 tagtttcgag tagtaagaa
//
LOCUS       DAIGUC010000211         4465 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.118, whole genome shotgun sequence.
ACCESSION   DAIGUC010000211 DAIGUC010000000
VERSION     DAIGUC010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.118"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            416..1894
                     /gene="msr(C)"
                     /locus_tag="NOB46_003015"
     CDS             416..1894
                     /gene="msr(C)"
                     /locus_tag="NOB46_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI1059850.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1941..2387
                     /locus_tag="NOB46_003016"
     CDS             1941..2387
                     /locus_tag="NOB46_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI1059851.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2586..3101)
                     /locus_tag="NOB46_003017"
     CDS             complement(2586..3101)
                     /locus_tag="NOB46_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI1059852.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3218..4419
                     /locus_tag="NOB46_003018"
                     /pseudo
     CDS             3218..4419
                     /locus_tag="NOB46_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         1343 a          748 c          967 g         1407 t
ORIGIN      
        1 cggtagaaga aggttacgag tctgttcgtt tagcaccaga aaagatcact acgttcgaat
       61 aaaaggtttt cagttactat tcagtagcta ttgctttttt tgaatcgtgt gtggtaacct
      121 aataaaaaag gaggtcggaa aaatgactgc atcgatgaaa ttacgtttcg aacttttgaa
      181 taacaactaa ataaattcaa aagacatgta taaacaacaa tttcatggat ggagtatgtc
      241 cattttttcg aacgacagta gaataggtga aagctatgac agatttggtg atttagtcat
      301 agttatttcg ttcagagtag gaaaagatgt gatgcagttt ttttgcaaac agatttttct
      361 gctctttttt agtatcgata attgttgttt tacatgaaat aggagtgtaa aacatatgga
      421 aaatttagca gtaaatataa caaatctaca agtcagcttt ggcaaccagc tagaactatc
      481 tattgattct cttcgtgtct atcagcaaga tcgtataggg atcataggag aaaatggtgt
      541 cggtaaatcg actttgctca aactaatagc cggtgaactt tttcccgatc atgggaaaat
      601 ccaaacagag atcaccttca actacctgcc tcaattaacc tatctcgctg aagcaaagga
      661 cctaaatttg gaattagcca gtcatttcca gttaagactg gaagaaactt cagagcggaa
      721 atggagcgga ggggaagaac gaaagatcga gttgatacgt cttctttctt cttatgaaca
      781 agggatgctt ctagacgagc caacaaccca tctagataga aaaagtattg atcgactgat
      841 tgaagagctt cgttattatt atggtacgct ggtttttgtt agtcatgatc gctattttct
      901 agatgagcta gcatcgaaaa tctgggaagt aaaagacgga gaaatccgag agttttcggg
      961 gaattatagt gcctatctca ctcaaaagga attggagaaa aagactcagc tacgagaagc
     1021 agagtcgatc atgaaagaga aaaaacgatt ggaaaaatcg atccaagaaa agaaaaaaca
     1081 agcggaaaag ttggaaaaag tgtccagtaa aaagaaaaag caacaaatca gaccggatcg
     1141 gttgtcttcc tctaaacaaa aagacagtgt acaaaaagcc atccaaaaga atgcgaaaac
     1201 attagagaga agactccaaa aaataggaga aacaaccaag ccgcagcaga tgaaacaaat
     1261 ccgttttcca gtaccaaaat ctcttgaact ccacagccgc tatcccatca tgggacaaaa
     1321 tgtccaattg gaaagaagtg ggagaacatt actggtaaat ggtgattttc agttttcttt
     1381 aggtaaaaaa atcgcgattg tcggtgaaaa tggttcaggt aagacaacct tattagaaca
     1441 tatccgcaaa caaggagaag gaatccttct ctctccgaaa gtaagctttc aagtatatca
     1501 gcaaaagggt tatcaaatga catctgaaga atccatcatt cgttttgtca tgagacaaac
     1561 agagttttca gaatcgcttg tccgtagttt gctgaatcac ttagggtttg ctcaggaaac
     1621 tttgacgaaa ccgttatgta cattaagtgg gggagaagcg acccgtctga cgattgcttt
     1681 gctttttact aagccaagta atgtgttgct gttagatgaa ccgactaatt ttattgatat
     1741 ggcaacgatc gaagctttag agaagctaat gcaaatatat ccgggaacga ttttgtttac
     1801 ttctcatgat tcttactttg tcgagcgtac ggctgatgaa gtttatgaaa taaaagggca
     1861 gaaaataaaa aaagtactta cgagaaattt ttaaatgtgc tacgatgatt ttcgtgacaa
     1921 atttaaagga gtggtacaga ttgcctacaa ataaaaaaga aggaataatt tttacaacaa
     1981 tgatgtgttt tttgatggtc ttggggatga gcgcgtataa tttatggctg catcaagatc
     2041 ttcatttatc aagtttgttg attggtctag tgcctggatt cgtggtggct ttcattttgg
     2101 atgtcttcat catcggtgtg ctggcgaaaa aaattgcctt taaactacca gtaaatccag
     2161 aaagcaaggt ccaaatgatc ttaactattt catgcttgat ggttttagga atggtgacat
     2221 gtatgtcttt attcggtgtg atcatggaac aaggaatacc tgatcaatta ttctctgctt
     2281 atatgaatgc ttggaaaatg aatgtgattg ccgctttacc gttgcagttg atcatcgttg
     2341 gcccgctttc aagaagtgtg ctaaaagcaa ttcaaagtaa tgaatgatgg aacactgtta
     2401 tttgaaaaaa ggccttggca tgctttttgt catagtctct tgaatgcagt tctagaaaaa
     2461 tagtgatccg aacgataggt tttggcctgt cgttcggatc gctttttctt ttccaactgt
     2521 attgctcttt tattgaagat aatttgctct tcaatagata tttctagaaa ggttctgttt
     2581 atcccttact caaaaaactg ctgcatttgt tctcttactt gctgacacca ttggagttcc
     2641 tgctgacaaa gcataattct gcgctggatc acaacataac gtccaaattc ttgtttcttg
     2701 tctagcgaga ggtcattcaa ttttttttga tttttttgca tgattttgtt cagctgttgt
     2761 tctctagtga atagcagtcc agtagctgtt gttttatcga gcgtcgaaaa agcatagatt
     2821 tttgctagaa attcatcttt ttgcgtagga gcgggagttt cctctttgat ccattcctct
     2881 acaagagcac gtccttcatc agtcaagtgg tagatctttt tttgagagtg ctcgtctttg
     2941 tccaaaacgg tcacataacc ctgctggtct aacttggcaa gcgttgtata gatctgactg
     3001 tgatgggctt cccaaaaaat tgtgatcagc tgcttcaatt catacccaga acgtggtttg
     3061 gataaaagca cgcataataa tatataggct aaagtattca taaaaatcct acctctcgtc
     3121 ttattttctt tattatatca cagtaaagtt tccacgtttt acatgtgcat atttacatgt
     3181 aaaataaatc atgtatgatg ctaatagaga gaaagggatg gaaatattgg agaatcaaat
     3241 agatatacaa gaacaaacaa atgaagaaac aaaggggaaa agttcagcgc tagttgtagc
     3301 agctacctgt atgatcgctt ttatgggagt gggtctagta gacccaatct taaaaacgat
     3361 tgctgcacag ttaaacgcta cgccagctga aacgaccctg ttatttacta gttacatgtt
     3421 agtcactggt gtggtgatgc tatttacagg tttcttatct agtcggatcg gtttgaaaaa
     3481 acattgatga caggattgtt tatcatcgtt gtattcgctg gtcttggcgg attatctggg
     3541 aatatcggaa tgctgattgg gttacgtgcc ggctggggtg tcgggaatgc tttatttgtc
     3601 tctactgctt tagcaacgat cgtcagtatt ttagttggta acacagaaaa agcaatcatg
     3661 atgtatgaag cagcacttgg ctgcggaatg gctgttggcc ctctagtcgg tggggtcttg
     3721 ggcagtggtt catggcgtta tccatttttt ggggtagcat ttttgatgtt ttgcggtttt
     3781 atagccctag cggtactttt acctgaaact gagaaaccaa agagaaaagt aggcctttgg
     3841 gaaggtgtca aagcgttaag caatcataaa cttcgttcag ttggactaat cgcattgtta
     3901 tataatttcg gattctttac tttacttgcg tatgcgccat ttttattgat tggctattct
     3961 gaattagaag tcggttttgt attttttggc tggggtgtgc ttctggctat tgcttcgatt
     4021 ttcgttgcac cggctcttga gcggaagttt acgacttatc ggacaatttt agcagcattt
     4081 gtcttattca ttatttgttt gctgttatta ggagctggaa cttctatgcc agtccttgta
     4141 ccgatcagca ttgtgttagc aggatttttc caaggaatta tcaatacact gttgacgacg
     4201 attgctatgg aaataccagg tctgcaacga aacgttgctt cgtccagcta tagttttgtc
     4261 cgctttttcg gtggagcttt agcaccattt attgcaggtg tgattggtga acatattggt
     4321 gaaagctatg cgttttattt tgcaggtgcc attgttctta tcagtgtatg ttgtatcatt
     4381 tatcaccgta attattttgc tacaaatgaa gaagaataag aaatcagagg ttgtgaaaaa
     4441 gctgtcctgc atcaagtcat aagaa
//
LOCUS       DAIGUC010000212         4195 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.125, whole genome shotgun sequence.
ACCESSION   DAIGUC010000212 DAIGUC010000000
VERSION     DAIGUC010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.125"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            62..1981
                     /gene="tet(M)"
                     /locus_tag="NOB46_003019"
     CDS             62..1981
                     /gene="tet(M)"
                     /locus_tag="NOB46_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCI1059853.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL
                     HPNMCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2091..2141
                     /locus_tag="NOB46_003020"
                     /pseudo
     CDS             2091..2141
                     /locus_tag="NOB46_003020"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            2175..3551
                     /gene="tet(L)"
                     /locus_tag="NOB46_003021"
     CDS             2175..3551
                     /gene="tet(L)"
                     /locus_tag="NOB46_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCI1059854.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
BASE COUNT         1342 a          633 c          856 g         1364 t
ORIGIN      
        1 taaaagtatt tatcactggg atttttatgc ccttttgggt ttttgaatgg aggaaaatca
       61 catgaaaatt attaatattg gagttttagc tcatgttgat gcaggaaaaa ctaccttaac
      121 agaaagctta ttatataaca gtggagcgat tacagaatta ggaagcgtgg acaaaggtac
      181 aacgaggacg gataatacgc ttttagaacg tcagagagga attacaattc agacaggaat
      241 aacctctttt cagtgggaaa atacgaaggt gaacatcata gacacgccag gacatatgga
      301 tttcttagca gaagtatatc gttcattatc agttttagat ggggcaattc tactgatttc
      361 tgcaaaagat ggcgtacaag cacaaactcg tatattattt catgcactta ggaaaatggg
      421 gattcccaca atctttttta tcaataagat tgaccaaaat ggaattgatt tatcaacggt
      481 ttatcaggat attaaagaga aactttctat ggaaattata atcaaacaga aagtagagct
      541 gcaccctaat atgtgtgtga tgagctgtac ggaacctgag caatgggatg tggtaataga
      601 aggaaatgat gaccttttag agaaatatat gtccggtaaa tcattagaag cattagaact
      661 cgaacaagag gaaatcagaa gatttcagaa ttgctccttg taccctgttt atcatggaag
      721 cgcaaaaagc aacataggga ttgagcagct tatagaagtg ataacgaata aattttattc
      781 atcaacatac agaaagaagt ctgaactttg cggaaatgtc ttcaaaattg aatattcgga
      841 agaaagacaa cgtcttgcat atgtacgcct ttatggcgga atcctgcatt tgcgggattc
      901 ggttagaata tcggaaaagg aaaaaataaa aattacagaa atgtatactt caataaatgg
      961 tgaattatgt aaaattgata aggcttattc cggggaaatt gttattttgc aaaatgagtt
     1021 tttgaagcta aatagtgttc ttggagatac aaagctattg ccacagagag agagaattga
     1081 aaatccgctc cctctgctgc aaacaactgt tgaaccgagc aaacctcaac aaagggaaat
     1141 gttacttgat gcacttttag aaatctccga cagtgacccg cttctacaat attatgtgga
     1201 ttctacgaca catgaaatta tactttcttt cttagggaaa gtacaaatgg aagtgattag
     1261 tgcactgttg caagaaaagt atcatgtgga gatagaacta aaagagccta cagtcattta
     1321 tatggagaga ccgttaaaaa atgcagaata taccattcac atcgaagtgc cgccaaatcc
     1381 tttctgggct tccattggtt tatctgtatc accgcttccg ttgggaagtg gaatgcagta
     1441 tgagagctcg gtttctcttg gatacttaaa tcaatcattt caaaatgcag ttatggaagg
     1501 gatacgctat ggttgcgaac aaggattata tggttggaat gtgacggatt gtaaaatctg
     1561 ttttaagtat ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc
     1621 tcctattgta ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct
     1681 tagttttaaa atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa
     1741 atattgtgcg aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga
     1801 aatccctgct cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg
     1861 tagtgtttgt ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca
     1921 gccccgtcgt ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta
     1981 gtgtatttta tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta
     2041 ataaagattt gaattaaagt gtaaaggagg aattaattat gaagtgaaat gaatgtaaca
     2101 gggttcaatt aaaagaggga agcgtatcat taaccctata aactacgtct gccctcatta
     2161 ttggagggtg aaatgtgaat acatcctatt cacaatcgaa tttacgacac aaccaaattt
     2221 taatttggct ttgcatttta tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct
     2281 cattacctga tattgcaaat gattttaata aaccacctgc gagtacaaac tgggtgaaca
     2341 cagcctttat gttaaccttt tccattggaa cagctgtata tggaaagcta tctgatcaat
     2401 taggcatcaa aaggttactc ctatttggaa ttataataaa ttgtttcggg tcggtaattg
     2461 ggtttgttgg ccattctttc ttttccttac ttattatggc tcgttttatt caaggggctg
     2521 gtgcagctgc atttccagca ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa
     2581 ataggggtaa agcatttggt cttattggat cgatagtagc catgggagaa ggagtcggtc
     2641 cagcgattgg tggaatgata gcccattata ttcattggtc ctatcttcta ctcattccta
     2701 tgataacaat tatcactgtt ccgtttctta tgaaattatt aaagaaagaa gtaaggataa
     2761 aaggtcattt tgatatcaaa ggaattatac taatgtctgt aggcattgta ttttttatgt
     2821 tgtttacaac atcatatagc atttcttttc ttatcgttag cgtgctgtca ttcctgatat
     2881 ttgtaaaaca tatcaggaaa gtaacagatc cttttgttga tcccggatta gggaaaaata
     2941 taccttttat gattggagtt ctttgtgggg gaattatatt tggaacagta gcagggtttg
     3001 tctctatggt tccttatatg atgaaagatg ttcaccagct aagtactgcc gaaatcggaa
     3061 gtgtaattat tttccctgga acaatgagtg tcattatttt cggctacatt ggtgggatac
     3121 ttgttgatag aagaggtcct ttatacgtgt taaacatcgg agttacattt ctttctgtta
     3181 gctttttaac tgcttccttt cttttagaaa caacatcatg gttcatgaca attataatcg
     3241 tatttgtttt aggtgggctt tcgttcacca aaacagttat atcaacaatt gtttcaagta
     3301 gcttgaaaca gcaggaagct ggtgctggaa tgagtttgct taactttacc agctttttat
     3361 cagagggaac aggtattgca attgtaggtg gtttattatc cataccctta cttgatcaaa
     3421 ggttgttacc tatggaagtt gatcagtcaa cttatctgta tagtaatttg ttattacttt
     3481 tttcaggaat cattgtcatt agttggctgg ttaccttgaa tgtatataaa cattctcaaa
     3541 gggatttcta aatcgttaag ggatcaactt tgggagagag ttcaaaattg atcctttttt
     3601 tataacagga attcaaatct ttttgttcca ttaaagggcg cgattgctga ataaaagata
     3661 cgagagacct ctcttgtatc ttttttattt tgagtggttt tgtccgttac actagaaaac
     3721 cgaaagacaa taaaaatttt attcttgctg agtctggctt tcggtaagct agacaaaacg
     3781 gacaaaataa aaattggcaa gggtttaaag gtggagattt tttgagtgat cttctcaaaa
     3841 aatactacct gtcccttgct gatttttaaa cgagcacgag agcaaaaccc ccctttgctg
     3901 aggtggcaga gggcaggttt ttttgtttct tttttctcgt aaaaaaaaga aaggtcttaa
     3961 aggttttatg gttttggtcg gcactgccga cagcctcgca gagcccacct ttacgaagta
     4021 aagtatagtg tgttatactt tacatggaag ttgtaccgaa atattgtgtt gtgaagtcta
     4081 tataatttta aaattatgaa gtctatatac gtgcgtaaag atatttaaag agattaaaaa
     4141 taataaaaat aaaaattgaa ttaaaaagag atatggttga ttattggaac gattg
//
LOCUS       DAIGUC010000213         3632 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.135, whole genome shotgun sequence.
ACCESSION   DAIGUC010000213 DAIGUC010000000
VERSION     DAIGUC010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.135"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            388..471
                     /locus_tag="NOB46_003022"
     CDS             388..471
                     /locus_tag="NOB46_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HCI1059855.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            596..1333
                     /gene="erm(B)"
                     /locus_tag="NOB46_003023"
     CDS             596..1333
                     /gene="erm(B)"
                     /locus_tag="NOB46_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI1059856.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1596..1712)
                     /locus_tag="NOB46_003024"
     CDS             complement(1596..1712)
                     /locus_tag="NOB46_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta-toxin"
                     /protein_id="HCI1059857.1"
                     /translation="MVQNQHQETPEFKAIQQKLESLQPPTPPIPKTPKLPGI"
     gene            1975..2487
                     /locus_tag="NOB46_003025"
                     /pseudo
     CDS             1975..2487
                     /locus_tag="NOB46_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337518.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2559..>3632)
                     /locus_tag="NOB46_003026"
     CDS             complement(2559..>3632)
                     /locus_tag="NOB46_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI1059858.1"
                     /translation="VLALVMSQIMATSTGATGSTLSLIGLLYIVRAGTDVSNLDLSMF
                     NPMGWIYLTYPFTENNWLPLLFALIFSLVFTVLAFVLEEHRDMGAGYLPEREGRATAK
                     KSLLSVPGLFFKINKGVMIGWLIAFVVMGAAYGSIYGDMQVFLGGNELMKQMFTQSGV
                     SIEESFTATIMMVMIGLVTILPIAVVNKLFAEETRLHLSQLYVTKITRGQLYWTTIFL
                     AIFAGVVGIGLASAGLGGTAISAMKNESTMDLTDFLAAGYNFLPSILFYIGLAALALG
                     WLPKFGKVIYAYLGYSFALNYFGGILDLPDWFSKTAIQSWIPRLPMEKFDGTIFAVIT
                     VISIVFLFVGYLGYKRRDMVEGA"
BASE COUNT         1224 a          654 c          644 g         1110 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacct tttgtacatt taacttgacg
       61 gtgacatctc tctattgtga gttattagtg gtacagtttt caaccgtttt aattataaaa
      121 aagtggtgca tttttaaatt ggcacaaaca ggtaacggtt attgcaggtg tatttcttat
      181 ctatgggttt aacatggatt ttatcattaa aatcatgagt attgtccgag agtgattggt
      241 cttgcgtatg gttaacccta aagttatgga aataagactt agaagcaaac ttaagagtgt
      301 gttgatagtg cattaaaaat tttgtataat aggaattgaa gttaaattag atgctaaaaa
      361 tttgtaatta agaaggaggg attcgtcatg ttggtattcc aaatgcgtta tgtagataaa
      421 acatctactg ttttgaaaca gactaaaaac agtgattacg cagataaata aatacgttag
      481 attaattcct accagtgact aatcttatga ctttttaaac agataactaa aattacaaac
      541 aaatcgttta acttctgtat ttgtttatag atgtaatcac ttcaggagtg attacatgaa
      601 caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca accaaataat
      661 aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag gtaaagggca
      721 tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat tagacagtca
      781 tctattcaac ttatcgtcag aaaaattaaa actgaatact cgtgtcactt taattcacca
      841 agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg ggagtattcc
      901 ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccatg cgtctgacat
      961 ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc gaacactagg
     1021 gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag cggaatgctt
     1081 tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata ccacagatgt
     1141 tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca atcgagaata
     1201 tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca aagtaaacaa
     1261 tttaagtacc gttacttatg agcaagtatt gtctattttt aatagttatc tattatttaa
     1321 cgggaggaaa taattctatg agtcgctttt gtaaatttgg aaagttacac gttactaaag
     1381 ggaatgtaga taaattatta ggtatagggc acctctaata actaccaatt aattcacctc
     1441 aaaatgaaat tagaaaaaaa cagcgaaatt tttaaatcta tttcttatcg atacaaattc
     1501 ctcgtaggcg ctcgggaccc caacatgagg aaatgttttt ataaaaaaag agtagttacc
     1561 gttttttggt aactactctt ttcctttttt aaggtttaaa tacctggaag tttaggtgtt
     1621 ttgggtattg gtggtgtagg tggctgcaag ctttccaatt tttgttgaat tgctttaaat
     1681 tcaggggttt cttggtgttg attttgaacc attttttgct ctattctctc caaagtcggt
     1741 tgaatttctt tccctgatac tttacgattt aattctcttt ctaaggtctc tttcggacta
     1801 atggaaggcg tttctaagct tgaatagagt ttcactcctt ctctattgta aagccttata
     1861 tcgctaaata agcccgtttt atgaagggtt tctaaattgg tcggtaagtt tttgacaaca
     1921 atatcatgcg cttgttttgg tggtgcccta gctgtcattg gatcatctgc atacaataag
     1981 atccatgaaa ggccatctgc tgccaatgag cgccttgaga ttggtaattg ggaagctgat
     2041 actgtagccg gtaaaacagg tagggctcgt attgtaactc tagtcgatcg tagatctcgt
     2101 ttctccctac ttggtaaggt tgaaaagaaa atctctaaaa atgtggttga ttgtatgatc
     2161 aatctactaa gaaatgtagg agaagataaa tgtaaaaccg ttacacccga tagaggaaaa
     2221 gaattctccc aacatagtcg aataacgcta gaattaaatg gcactaaagt gtattttcca
     2281 gatccacatg ctccatggca acgtggtaca aacgaaaata ctaatggttt attacgagaa
     2341 tattcaccca aaggtgaaga tatttcaggt attttcgata gtcaaattca agaatgggcg
     2401 aataaattaa acacgcgacc acggaaatgt ctaaattgga aaacccctta tgaagtattt
     2461 tttaatgaat cgttgcactt aatttgacaa ttgaagccat aaaaaaaccg ctcaaatcga
     2521 ctttcgtaaa tatgaacggt tttttagaaa ttcaattttt aagcgccttc taccatatca
     2581 cggcgtttgt atcctaaata gccgacaaat aagaagacga tactgataac agtaattact
     2641 gcaaaaatcg ttccatcaaa tttttccatc ggtaagcgtg gaatccaact ttgaattgca
     2701 gtttttgaga accaatccgg caaatctaag attccgccga aataattcaa agcaaaggaa
     2761 tagcctagat aagcatagat tacttttcca aattttggca accagcctaa cgctaaagca
     2821 gccaaaccaa tataaaataa gatggaaggg agaaaattgt atccagcagc taagaaatcg
     2881 gtcagatcca tagtcgattc atttttcatc gcagaaatcg ccgttccacc taatcccgct
     2941 gatgctaagc caatacctac gactccagca aaaatagcta aaaatatcgt tgtccaatat
     3001 aattggcctc gcgtaatctt cgttacatac agttgactca gatgcagtct tgtttcttct
     3061 gcaaataatt tattgaccac cgcgattggc aagattgtga ctaatccaat cattaccatc
     3121 atgatcgttg ccgtaaagga ttcttcaatg gaaacgccag attgagtgaa catttgtttc
     3181 atcagttcat ttccgccaag aaagacttgc atgtctccat aaatggagcc atacgcagct
     3241 cccataacga caaatgcgat cagccaacca atcattactc ctttattaat cttgaaaaac
     3301 aaaccaggta cagaaagtag tgatttcttc gccgtcgcac gtccttctcg ttcaggaaga
     3361 taacctgcgc ccatgtcgcg atgttcttcc aacacaaacg caagtacggt aaaaacaaga
     3421 ctaaaaatca aagcaaataa taatggtagc cagttatttt ctgtgaaagg ataggtcaag
     3481 taaatccatc ccattggatt gaacattgat aaatcaagat tagacacatc tgttccagcg
     3541 cgcacgatat acaaaagtcc tataagactt aatgtcgagc cggttgctcc agtagaagtc
     3601 gccataatct gcgacatcac aagtgccaat ac
//
LOCUS       DAIGUC010000214         2209 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.148, whole genome shotgun sequence.
ACCESSION   DAIGUC010000214 DAIGUC010000000
VERSION     DAIGUC010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.148"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..115
                     /locus_tag="NOB46_003027"
     CDS             <1..115
                     /locus_tag="NOB46_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI1059859.1"
                     /translation="LFDSRFKTLQQNPVNQICEITNVSRASLYRKLSEVNN"
     gene            329..1024
                     /gene="vanR"
                     /locus_tag="NOB46_003028"
     CDS             329..1024
                     /gene="vanR"
                     /locus_tag="NOB46_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI1059860.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1002..2156
                     /locus_tag="NOB46_003029"
     CDS             1002..2156
                     /locus_tag="NOB46_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI1059861.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          740 a          408 c          467 g          594 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccct gtaaatcaaa tttgtgaaat
       61 tactaatgta tctagggctt cattatacag gaaattatca gaagtgaata attagccatt
      121 ctgtattccg ctaatgggca atatttttaa agaagaaaag gaaactataa aatattaaca
      181 gcctcctagc gatgccgaaa agccctttga taaaaaaaga atcatcatct taagaaattc
      241 ttagtcattt attatgtaaa tgcttataaa ttcggcccta taatctgata aattattaag
      301 ggcaaactta tgtgaaaggg tgataactat gagcgataaa atacttattg tggatgatga
      361 acatgaaatt gccgatttgg ttgaattata cttaaaaaac gagaattata cggttttcaa
      421 atactatacc gccaaagaag cattggaatg tatagacaag tctgagattg accttgccat
      481 attggacatc atgcttcccg gcacaagcgg ccttactatc tgtcaaaaaa taagggacaa
      541 gcacacctat ccgattatca tgctgaccgg gaaagataca gaggtagata aaattacagg
      601 gttaacaatc ggcgcggatg attatataac gaagcccttt cgcccactgg agttaattgc
      661 tcgggtaaag gcccagttgc gccgatacaa aaaattcagt ggagtaaagg agcagaacga
      721 aaatgttatc gtccactccg gccttgtcat taatgttaac acccatgagt gttatctgaa
      781 cgagaagcag ttatccctta ctcccaccga gttttcaata ctgcgaatcc tctgtgaaaa
      841 caaggggaat gtggttagct ccgagctgct atttcatgag atatggggcg acgaatattt
      901 cagcaagagc aacaacacca tcaccgtgca tatccggcat ttgcgcgaaa aaatgaacga
      961 caccattgat aatccgaaat atataaaaac ggtatggggg gttggttata aaattgaaaa
     1021 ataaaaaaaa cgactattcc aaactagaac gaaaacttta catgtatatc gttgcaattg
     1081 ttgtggtagc aattgtattc gtgttgtata ttcgttcaat gatccgaggg aaacttgggg
     1141 attggatctt aagtattttg gaaaacaaat atgacttaaa tcacctggac gcgatgaaat
     1201 tatatcaata ttccatacgg aacaatatag atatctttat ttatgtggcg attgtcatta
     1261 gtattcttat tctatgtcgc gtcatgcttt caaaattcgc aaaatacttt gacgagataa
     1321 ataccggcat tgatgtactt attcagaacg aagataaaca aattgagctt tctgcggaaa
     1381 tggatgttat ggaacaaaag ctcaacacat taaaacggac tctggaaaag cgagagcagg
     1441 atgcaaagct ggccgaacaa agaaaaaatg acgttgttat gtacttggcg cacgatatta
     1501 aaacgcccct tacatccatt atcggttatt tgagcctgct tgacgaggct ccagacatgc
     1561 cggtagatca aaaggcaaag tatgtgcata tcacgttgga caaagcgtat cgactcgaac
     1621 agctaatcga cgagtttttt gagattacac ggtataacct acaaacgata acgctaacaa
     1681 aaacgcacat agacctatac tatatgctgg tgcagatgac cgatgaattt tatcctcagc
     1741 tttccgcaca tggaaaacag gcggttattc acgcccccga ggatctgacc gtgtccggcg
     1801 accctgataa actcgcgaga gtctttaaca acattttgaa aaacgccgct gcatacagtg
     1861 aggataacag catcattgac attaccgcgg gcctctccgg ggatgtggtg tcaatcgaat
     1921 tcaagaacac tggaagcatc ccaaaagata agctagctgc catatttgaa aagttctata
     1981 ggctggacaa tgctcgttct tccgatacgg gtggcgcggg acttggattg gcgattgcaa
     2041 aagaaattat tgttcagcat ggagggcaga tttacgcgga aagcaatgat aactatacga
     2101 cgtttagggt agagcttcca gcgatgccag acttggttga taaaaggagg tcctaagaga
     2161 tgtatataat tttggctctt tgtcaaatga tgttggtaaa gagaaatct
//
LOCUS       DAIGUC010000215         1743 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.158, whole genome shotgun sequence.
ACCESSION   DAIGUC010000215 DAIGUC010000000
VERSION     DAIGUC010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.158"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            13..378
                     /locus_tag="NOB46_003030"
     CDS             13..378
                     /locus_tag="NOB46_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1059862.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEKLGG
                     KNDYKDEIVYVYDYEKGDK"
     gene            379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB46_003031"
     CDS             379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB46_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HCI1059863.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVY"
BASE COUNT          718 a          133 c          298 g          594 t
ORIGIN      
        1 attgatgata atatggtttt tgatattgat aatttaaaag gatttcttaa tgataccagt
       61 tcatttgggt ttatagctaa agaaaataat aaaattatag gatttgcata ttgctataca
      121 cttttaagac ctgatggaaa aacaatgttt tatttacact caataggaat gttacctaac
      181 tatcaagaca aaggttatgg ttcaaaatta ttatctttta ttaaggaata ttctaaagag
      241 attggttgtt ctgaaatgtt tttaataact gataaaggta atcctagagc ttgccatgta
      301 tatgaaaaat taggtggtaa aaatgattat aaagatgaaa tagtatatgt atatgattat
      361 gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa tatgtataag aactttaata
      421 gatgatgatt ttcctttgat gttaaaatgg ttaactgatg aaagagtatt agaattttat
      481 gatggtagag ataaaaaata tacattagaa tcattaaaaa aacattatac agagccttgg
      541 gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg atatggacaa
      601 atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac tgatgagata
      661 gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg aattggtaca
      721 agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa tgcagttatt
      781 ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc tggttttaga
      841 attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga ttgttattta
      901 atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata tttaattgag
      961 cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg ttatgatagt
     1021 gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac taataagaaa
     1081 aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt agaaactaat
     1141 gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat actaggttat
     1201 aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc agaagaagaa
     1261 caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg tttagattat
     1321 acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga gtatatattg
     1381 ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat agaaagtttt
     1441 atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg ccataatgat
     1501 tttagttgta atcatctatt gttagatggc aataatagat taactggaat aattgatttt
     1561 ggagattctg gaattataga tgaatattgt gattttatat acttacttga agatagtgaa
     1621 gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa tatagatatt
     1681 gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga aactattgtt
     1741 tat
//
LOCUS       DAIGUC010000216         1743 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.159, whole genome shotgun sequence.
ACCESSION   DAIGUC010000216 DAIGUC010000000
VERSION     DAIGUC010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.159"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            13..378
                     /locus_tag="NOB46_003032"
     CDS             13..378
                     /locus_tag="NOB46_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI1059864.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEKLGG
                     KNDYKDEIVYVYDYEKGDK"
     gene            379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB46_003033"
     CDS             379..>1743
                     /gene="aph(2'')-I"
                     /locus_tag="NOB46_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HCI1059865.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVY"
BASE COUNT          717 a          133 c          299 g          594 t
ORIGIN      
        1 attgatgata atatggtttt tgatattgat aatttaaaag gatttcttaa tgataccagt
       61 tcatttgggt ttatagctaa agaaaataat aaaattatag gatttgcata ttgctataca
      121 cttttaagac ctgatggaaa aacaatgttt tatttacact caataggaat gttacctaac
      181 tatcaagaca aaggttatgg ttcaaaatta ttatctttta ttaaggaata ttctaaagag
      241 attggttgtt ctgaaatgtt tttaataact gataaaggta atcctagagc ttgccatgta
      301 tatgaaaaat taggtggtaa aaatgattat aaagatgaaa tagtatatgt atatgattat
      361 gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa tatgtataag aactttaata
      421 gatgatgatt ttcctttgat gttaaaatgg ttaactgatg aaagagtatt agaattttat
      481 ggtggtagag ataaaaaata tacattagaa tcattaaaaa aacattatac agagccttgg
      541 gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg atatggacaa
      601 atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac tgatgagata
      661 gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg aattggtaca
      721 agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa tgcagttatt
      781 ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc tggttttaga
      841 attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga ttgttattta
      901 atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata tttaattgag
      961 cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg ttatgatagt
     1021 gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac taataagaaa
     1081 aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt agaaactaat
     1141 gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat actaggttat
     1201 aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc agaagaagaa
     1261 caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg tttagattat
     1321 acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga gtatatattg
     1381 ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat agaaagtttt
     1441 atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg ccataatgat
     1501 tttagttgta atcatctatt gttagatggc aataatagat taactggaat aattgatttt
     1561 ggagattctg gaattataga tgaatattgt gattttatat acttacttga agatagtgaa
     1621 gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa tatagatatt
     1681 gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga aactattgtt
     1741 tat
//
LOCUS       DAIGUC010000217         1309 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.167, whole genome shotgun sequence.
ACCESSION   DAIGUC010000217 DAIGUC010000000
VERSION     DAIGUC010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.167"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..>1309
                     /locus_tag="NOB46_003034"
     CDS             <1..>1309
                     /locus_tag="NOB46_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HCI1059866.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          553 a          101 c          224 g          431 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagatt
//
LOCUS       DAIGUC010000218         1205 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1183-ENTFAE
            SAMN29456777-rid14857683.guided.168, whole genome shotgun sequence.
ACCESSION   DAIGUC010000218 DAIGUC010000000
VERSION     DAIGUC010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456777
            Sequence Read Archive: SRR19916779
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361054.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361054.1
            Genome Coverage       :: 114x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 03:47:51
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,036
            CDSs (total)                      :: 2,969
            Genes (coding)                    :: 2,877
            CDSs (with protein)               :: 2,877
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 40 of 92
            Pseudo Genes (incomplete)         :: 41 of 92
            Pseudo Genes (internal stop)      :: 24 of 92
            Pseudo Genes (multiple problems)  :: 12 of 92
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456777-rid14857683.guided.168"
                     /strain="microbial"
                     /isolate="V1183-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-10-19"
     gene            <1..261
                     /locus_tag="NOB46_003035"
     CDS             <1..261
                     /locus_tag="NOB46_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI1059867.1"
                     /translation="FNDLHILQPDWKTIERTSDRAMVFMLLNDEEEWGKLERRTKNKY
                     KKLIKEISLIDLTDLMKSTLKANEKQLQKQIDFWQREFRFWK"
     gene            396..1043
                     /locus_tag="NOB46_003036"
     CDS             396..1043
                     /locus_tag="NOB46_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HCI1059868.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT          471 a          117 c          186 g          431 t
ORIGIN      
        1 tttaatgatt tacatatatt acaaccagat tggaaaacta tcgaacgtac ttctgataga
       61 gcaatggttt ttatgttgtt gaatgatgaa gaagaatggg gaaaattaga aagacgtact
      121 aagaataaat ataaaaaatt aattaaagaa atatctctaa ttgatttaac tgatttaatg
      181 aaatcgactt taaaagcgaa cgaaaaacaa ttgcaaaagc agattgattt ttggcaacgt
      241 gaatttagat tttggaagta aagtaacttt gttttataca aaatgttact ttagtataat
      301 taacgtttaa gaggtgacac aatatatgaa aaaatcagag gattattcct cctaaataca
      361 aagagataag atgaaattta ggaggaaaat tatatatgac ttttaatatt attaatttgg
      421 aaacttggga tagaaaagaa tattttaatc attatttcaa tcaacaaaca acttacagtg
      481 ttactaaaga atttgatatc actttactta aaagtatgat aaaaaataaa ggatatgaac
      541 tgtatcctgc tttgatttat acaattgtaa atattataaa tcaaaataaa gtatttagaa
      601 caggaattaa tagtgaggga aatttgggtt attgggaaaa attaaaccct ttatatacag
      661 tctttaataa agaaactgaa aaattttcta acatttggac agaatcaaat gttagtttta
      721 attcttttta taatagttat aagagtgact tacttgaata taaagataaa aatgaaatgt
      781 ttcctaaaaa accaatacct gaaaacacag ttcctatttc gatgattcct tggattgatt
      841 ttagttcatt taatttaaat attggtaata atagtagatt cctattgcca attattacaa
      901 taggtaaatt ttatagtaag aataataaga tctatttacc agtctcattg caagttcatc
      961 atgcggtatg tgatggttac catgtttcat tatttatgag tgaatttcaa aatatagttg
     1021 atagtgtaaa tgaatggatt taaatctaaa ataactttca taaacttaag taattatgat
     1081 atttataagt ttatagcaac taccattttt ggttgctggt gttttgattt tgaatttggt
     1141 tttgaactta tggactgatt tattcaggct ctttgtcaaa tgatgttggt aaagagaaat
     1201 cttag
//
